ライフサイエンスコーパス: vitamin B

1 in pyrophosphate (TPP) is the active form of vitamin B(1) and works as an essential cofactor for enzy

2 of biofortification of crops with increased vitamin B(1) content to improve human health.

3 We summarize the importance of vitamin B(1) in plants from the perspective of food secu

4 This study shows the potential role of vitamin B(1) in the diurnal regulation of central carbon

5 Vitamin B(1) is also emerging as an important component

6 Moreover, vitamin B(1) is also vital for plants themselves, and it

7 Vitamin B(1) is an essential dietary component, and defi

8 The predominant source of dietary vitamin B(1) is plant-based foods.

9 In general, vitamin B(1) is well-characterized for its role as a coe

10 Fibromyalgia, low LDL levels, high vitamin B(1) levels and IBS before RYGB were independent

11 ere, we focus on the importance of thiamine (vitamin B(1)) in plant health and discuss its impact on

12 lant health, including the role of thiamine (vitamin B(1)), iron, and the plant immune system; how pl

13 and measured serial plasma concentrations of vitamin B(1), B(6), B(12), C and D, folate, selenium, zi

14 also contained 100 mg vitamin B-6 and 100 mg vitamin B-1) on vitamin B-12 status and neurophysiologic

15 Although Mtb can synthesize vitamin B(12) (cobalamin) de novo, uptake of cobalamin h

16 F were identical to experiments with TCM and Vitamin B(12) (epsilon(13)C(Vitamin B12) = -26.0 +/- 0.9

17 ), folate (n = 3), vitamin B(6) (n = 1), and vitamin B(12) (n = 14) levels, and the corresponding dat

18 alterations result in malabsorption of iron, vitamin B(12) (pernicious anaemia) and potentially other

19 the natural cobalt-corrins cobyric acid and vitamin B(12) , respectively.

20 er, the gamma and alpha AOA lineages rely on vitamin B(12) -independent MetE and B(12) -dependent Met

21 n (Nibl), a new transition-metal analogue of vitamin B(12) .

22 owed an improved bioavailability of 151% for vitamin B(12) and 109% for vitamin D(3) in comparison wi

23 The present work aimed at encapsulation of vitamin B(12) and D(3) by spray drying using experimenta

24 d a suitable medium to provide water soluble vitamin B(12) and fat soluble vitamin D(3) in single pro

25 Vitamin B(12) and other cobamides are essential cofactor

26 Vitamin B(12) and vitamin D(3) deficiencies are reported

27 o reveal different reduction mechanisms with vitamin B(12) as a model reactant for reductive dehaloge

28 Replacing the central cobalt ion of vitamin B(12) by other metals has been a long-held aspir

29 entally benign solvent, and the synthesis of vitamin B(12) component on the gram scale.

30 In humans, vitamin B(12) deficiency causes peripheral and CNS manif

31 Neuropathology of vitamin B(12) deficiency in the Cd320(-/-) mouse.

32 o investigate the pathologic consequences of vitamin B(12) deficiency.

33 provides a direct link among dietary folate/vitamin B(12) exposure, the activity of the enzyme methy

34 the first validated report on the content of vitamin B(12) in edible insects.

35 idation of a method for the determination of vitamin B(12) in mealworm (Tenebrio molitor larvae), cri

36 aboration that led to the total synthesis of vitamin B(12) is also discussed.

37 In humans, cobalamin or vitamin B(12) is delivered to two target enzymes via a c

38 Vitamin B(12) is the only known essential human micronut

39 Genetically higher vitamin B(12) levels were not associated with any stroke

40 Cobamides are a group of compounds including vitamin B(12) that can vary at the lower base position o

41 nt work, the Escherichia coli outer membrane vitamin B(12) transporter, BtuB, was spin-labeled, and d

42 of BtuB, the Escherichia coli TonB-dependent vitamin B(12) transporter, in whole cells.

43 Found levels of vitamin B(12) were 1.08 ug/100 g for mealworm, 2.88 ug/1

44 Supplementation of cultures with cobalamin (vitamin B(12)) increased nitrite oxidation rates and sti

45 ro experiments with reduced corrinoid (i.e., vitamin B(12)) mediated reductive dechlorination of CFC-

46 ophylls, hemes, siroheme, corrins (including vitamin B(12)), coenzyme F(430), heme d (1), and bilins.

47 the family of enzyme cofactors that includes vitamin B(12)), is widely used for a variety of microbia

48 g Dehalococcoides whose growth is cobalamin (vitamin B(12))-dependent.

49 Hemoglobin, iron, ferritin, folate and vitamin B(12), in addition to many other laboratory indi

50 thylbenzimidazole (DMB), the lower ligand of vitamin B(12), involves five reactions catalyzed by the

51 The free radical-neutralizing vitamin B(12)-analog cobinamide completely prevents age-

52 Initially we confirmed expression of vitamin B(12)-internalization receptor (CD320) by Calu-3

53 omplexes with a new 'complexing excipient' - vitamin B(12)-targeted poly(ethylene glycol)-block-poly(

54 e aim of this study was to determine whether vitamins B(12), B(6), and folic acid lower homocysteine

55 icipants had vitamin B-12 deficiency (plasma vitamin B-12 < 148 pmol/L or MMA > 271 nmol/L), but none

56 as methylmalonic acid > 271 nmol/L or serum vitamin B-12 < 150 pmol/L.

57 m 0.4 to 7%), RBP (35%), selenium (70%), and vitamin B-12 (0.1%), yet for maternal intakes only a pos

58 Vitamin B-12 (cobalamin) deficiency may produce severe n

59 Poor vitamin B-12 (cobalamin) status is widespread in South A

60 vegans received either a placebo (n = 34) or vitamin B-12 (n = 42) toothpaste.

61 The tissue concentration of vitamin B-12 (P = 0.003), but not folate, and the activi

62 .62; 95% CI: 0.97, 4.28; P-trend = 0.02) and vitamin B-12 (quartile 5 compared with quartile 1: 2.08;

63 Low-normal concentrations of vitamin B-12 (VitB12) may be associated with worse cogni

64 of a single intramuscular injection of 10 mg vitamin B-12 (which also contained 100 mg vitamin B-6 an

65 included showed a decrease in mean or median vitamin B-12 across trimesters.

66 p (mean +/- SD change: 81 +/- 135 pmol/L for vitamin B-12 and 26 +/- 34 pmol/L for holotranscobalamin

67 ) in these populations, the relation between vitamin B-12 and birth weight (BW) elsewhere is unknown.

68 iologically active form of vitamin B-6), and vitamin B-12 and breast cancer risk in women with a BRCA

69 om serologic tests) had lower mean levels of vitamin B-12 and folate (data collected from 2009 throug

70 imed to evaluate whether the availability of vitamin B-12 and folate and the expression or activity o

71 Mean levels of vitamin B-12 and folate are lower in individuals with un

72 Vitamin B-12 and folate are micronutrients essential for

73 Vitamin B-12 and folate deficiencies in women and childr

74 ntly associated with anemia, but malaria and vitamin B-12 and folate deficiencies were not.The contri

75 There is evidence that low plasma vitamin B-12 and folate individually, as well as an imba

76 erum folate; P-interaction = 0.0078) for low vitamin B-12 and high folate status.

77 Non-Hispanic white persons had lower vitamin B-12 and higher MMA concentrations than non-Hisp

78 tion.Both postintervention concentrations of vitamin B-12 and holotranscobalamin and their changes ov

79 Low plasma vitamin B-12 and low plasma folate were each associated

80 d AF (OR: 1.97; 95% CI: 1.30, 2.97); but low vitamin B-12 and lower UMFA (OR: 1.69; 95% CI: 1.16, 2.4

81 he central 95% reference intervals for serum vitamin B-12 and MMA concentrations were widest for pers

82 enerally significantly associated with serum vitamin B-12 and MMA concentrations.

83 We examined cross-sectional data for serum vitamin B-12 and MMA in adults participating in the NHAN

84 dy was to describe the distribution of serum vitamin B-12 and MMA in US adults, and estimate age-spec

85 40 compared with -0.036 +/- 0.544 mumol/L in vitamin B-12 and placebo groups, respectively; P < 0.001

86 and alpha1-acid glycoprotein (AGP) and serum vitamin B-12 and serum and RBC folate among nonpregnant

87 deficiency, iron deficiency anemia, and low vitamin B-12 and, in Kenya, a lower prevalence of folate

88 Folate and vitamin B-12 are essential micronutrients involved in th

89 ts (n = 30 in the placebo arm; n = 36 in the vitamin B-12 arm) completed the intervention.

90 Vitamin B-12 bioavailability is dose dependent and at a

91 min B-12 status was the reference group, low vitamin B-12 combined with high UMFA was associated with

92 - SD age: 73 +/- 3 y; women: 47%) with serum vitamin B-12 concentrations <120 pmol/L at screening.

93 serum MMA concentrations, but not with serum vitamin B-12 concentrations after controlling for covari

94 We studied folate and vitamin B-12 concentrations and activity, expression, an

95 lysis showed nonsignificantly lower maternal vitamin B-12 concentrations in LBW than in normal-BW inf

96 Plasma folate, PLP, and vitamin B-12 concentrations were categorized dichotomous

97 Plasma PLP and vitamin B-12 concentrations were not associated with bre

98 y community-dwelling Chileans with low serum vitamin B-12 concentrations who were consuming bread for

99 arian populations and that concentrations of vitamin B-12 decrease from the first to the third trimes

100 5% based on body iron), selenium (2.5%), and vitamin B-12 deficiency (0%) were low compared with defi

101 Nine percent of participants had vitamin B-12 deficiency (plasma vitamin B-12 < 148 pmol/

102 We could not examine the interaction for vitamin B-12 deficiency and high plasma folate, because

103 cused on exacerbation of clinical effects of vitamin B-12 deficiency and its role in neurocognitive h

104 Overt vitamin B-12 deficiency causes neurologic disturbances i

105 studies are needed to examine the effect of vitamin B-12 deficiency in the presence of high exposure

106 be given to identification and treatment of vitamin B-12 deficiency in this population.

107 Vitamin B-12 deficiency is widespread in many parts of t

108 Vitamin B-12 deficiency was prevalent and clearly associ

109 include elevated folate and, less commonly, vitamin B-12 deficiency, or other nutritional deficienci

110 he blood of vegans who are at higher risk of vitamin B-12 deficiency.

111 ss healthy older population with more severe vitamin B-12 deficiency.

112 Of infants, 11.4% were vitamin B-12 deficient and 31.7% marginally deficient at

113 Correlation coefficients between CRP and vitamin B-12 for WRA and PSC ranged from -0.25 to 0.16,

114 ulting from any form of folate intake affect vitamin B-12 function and its roles in sustaining health

115 se health effects other than those linked to vitamin B-12 function?

116 their changes over 12 wk were higher in the vitamin B-12 group (mean +/- SD change: 81 +/- 135 pmol/

117 6 mumol/L, respectively) were greater in the vitamin B-12 group than in the placebo group.

118 associated with a dramatic decrease of liver vitamin B-12 in 2 cases.

119 We confirmed the decreased vitamin B-12 in cord blood from NTD pregnancies.

120 The decreased vitamin B-12 in liver and cord blood and decreased expre

121 We suggest evaluating vitamin B-12 in the nutritional recommendations for prev

122 ng a standardized score for each study (mean vitamin B-12 insufficiency / cutoff value), which intern

123 Our review indicates that vitamin B-12 insufficiency during pregnancy is common ev

124 iew to assess 1) the worldwide prevalence of vitamin B-12 insufficiency in pregnancy and 2) its assoc

125 Vitamin B-12 insufficiency in pregnancy is high in certa

126 The pooled estimates of vitamin B-12 insufficiency were 21%, 19%, and 29% in the

127 is study was to assess whether folate and/or vitamin B-12 intake are asssociated with genome-wide cha

128 e regarding niacin, folate, vitamin B-6, and vitamin B-12 intake in relation to cognitive function is

129 ability of vitamin B-12 to tissues even when vitamin B-12 intake is adequate.

130 In the categorical model, vitamin B-12 intake was associated with 29 DMRs annotate

131 Vitamin B-12 intake was not associated with DMPs.

132 igenome-wide association study of folate and vitamin B-12 intake was performed on DNA from 5841 parti

133 tic loci that are associated with folate and vitamin B-12 intake.

134 Folate and vitamin B-12 intakes were calculated from food-frequency

135 The measurement of bioavailability of vitamin B-12 is etiologically important in deficiency bu

136 Serum vitamin B-12 is measured to evaluate vitamin B-12 status

137 aste enters the circulation and corrects the vitamin B-12 markers in the blood of vegans who are at h

138 Changes in vitamin B-12 markers were more prominent in vegans who r

139 The oral application of vitamin B-12 may prevent its deficiency if the vitamin i

140 ss the effect of parenteral replenishment of vitamin B-12 on the bioavailability.

141 nsistent correlations between CRP or AGP and vitamin B-12 or folate biomarkers, there is no rationale

142 Spearman correlations between CRP or AGP and vitamin B-12 or folate concentrations were examined, tak

143 ion when estimating population prevalence of vitamin B-12 or folate deficiencies in WRA or PSC.

144 Correlations between inflammation and vitamin B-12 or folate were weak, with no clear pattern

145 We tested vitamin B-12 plasma concentrations by using chemilumines

146 25 to 0.16, and correlations between AGP and vitamin B-12 ranged between -0.07 and 0.14.

147 Serum vitamin B-12 showed little, whereas serum MMA showed not

148 12 status, including a combined indicator of vitamin B-12 status (3cB12) and scores on the ASQ-3 and

149 transcobalamin, and a composite indicator of vitamin B-12 status (cB-12).

150 min into one variable [combined indicator of vitamin B-12 status (cB-12)].

151 00 mg vitamin B-6 and 100 mg vitamin B-1) on vitamin B-12 status and neurophysiologic function in eld

152 MMA in a healthy subpopulation with replete vitamin B-12 status and normal renal function.

153 or serum total folate > 74.1 nmol/L, and low vitamin B-12 status as methylmalonic acid > 271 nmol/L o

154 Asymptomatic Chilean elderly with poor vitamin B-12 status displayed improved conductivity in m

155 Insufficient vitamin B-12 status has been linked to poor neurodevelop

156 MMA reference intervals to better interpret vitamin B-12 status in epidemiologic research.

157 hildren.We measured the associations between vitamin B-12 status in infancy (2-12 mo) and the develop

158 and block construction scores, respectively.Vitamin B-12 status in infancy is associated with develo

159 The long-term effects of poor vitamin B-12 status in infancy need further investigatio

160 act for neurologic disease of moderately low vitamin B-12 status in older people is unclear.

161 We aimed to determine whether vitamin B-12 status is associated with electrophysiologi

162 ic function in asymptomatic elderly with low vitamin B-12 status or whether folate status affects res

163 e functioning in Nepalese children 5 y later.Vitamin B-12 status was assessed in infancy with the use

164 Vitamin B-12 status was assessed with the use of total v

165 Vitamin B-12 status was defined by combining vitamin B-1

166 eraction models, when high folate and normal vitamin B-12 status was the reference group, low vitamin

167 re was also no evidence of an association of vitamin B-12 status with clinical markers of neurologic

168 on of the coexistence of high folate and low vitamin B-12 status with cognitive function, utilizing v

169 d not show any association of any measure of vitamin B-12 status with either peripheral or central ne

170 e ASQ-3 and NEPSY II subtests.All markers of vitamin B-12 status with the exception of plasma cobalam

171 We examined dietary and plasma folate and vitamin B-12 status, and their interaction, in relation

172 europathy in the elderly, even with a normal vitamin B-12 status, especially if their folate intake i

173 odels, we estimated the associations between vitamin B-12 status, including a combined indicator of v

174 l as an imbalance of high folic acid and low vitamin B-12 status, may be associated with lower cognit

175 Serum vitamin B-12 is measured to evaluate vitamin B-12 status.

176 h folic acid exposures are combined with low vitamin B-12 status.

177 is associated with a progressive decline in vitamin B-12 status.

178 function in older people with moderately low vitamin B-12 status.

179 symptomatic older people with moderately low vitamin B-12 status.

180 (MMA) is a specific functional indicator of vitamin B-12 status; however, concentrations increase wi

181 Parenteral replenishment of the vitamin B-12 store in deficient individuals prior to the

182 before and after parenteral replenishment of vitamin B-12 stores, from the kinetics of its plasma app

183 ate analyses, age, race/Hispanic origin, and vitamin B-12 supplement use were generally significantly

184 It is uncertain whether vitamin B-12 supplementation can improve neurophysiologi

185 r whether folate status affects responses to vitamin B-12 supplementation.

186 vegans who reported that they had not taken vitamin B-12 supplements.Vitamin B-12 that is applied to

187 they had not taken vitamin B-12 supplements.Vitamin B-12 that is applied to the oral cavity via toot

188 This effect may reduce the availability of vitamin B-12 to tissues even when vitamin B-12 intake is

189 The 776C-->G polymorphism of the vitamin B-12 transport protein transcobalamin gene (TCN2

190 tivity in myelinated peripheral nerves after vitamin B-12 treatment and an interaction with folate st

191 BW infants and higher odds of LBW with lower vitamin B-12 values (adjusted OR: 1.70; 95% CI: 1.16, 2.

192 Low vitamin B-12 was associated with cognitive impairment bo

193 Vitamin B-12 was measured by electrochemiluminescence as

194 Deficient compared with higher vitamin B-12 was significantly associated with lower cog

195 variates, high plasma folate and high plasma vitamin B-12 were each positively associated with global

196 l binding protein (RBP), zinc, selenium, and vitamin B-12 were measured at 5 mo (n = 163).

197 erum concentration biomarkers: folate, 0.49; vitamin B-12, 0.51; alpha-carotene, 0.53; beta-carotene,

198 We synthesized a stable isotope-labeled vitamin B-12, [13C]-cyanocobalamin, using Salmonella ent

199 regnancy body mass index, and plasma folate, vitamin B-12, and choline concentrations.

200 d biomarkers for iron, vitamin A, vitamin D, vitamin B-12, and folate from 0 to 35 d post-norovirus e

201 to types and amounts of CFBs and vitamin D, vitamin B-12, and folate status, or the relation between

202 Plasma folate, vitamin B-12, and methylmalonic acid (MMA) were assessed

203 including carotenoids, tocopherols, folate, vitamin B-12, and phospholipid fatty acids, were collect

204 n, serum iron, erythropoietin, serum folate, vitamin B-12, C-reactive protein, and interleukin-6.

205 micronutrient status (iron, zinc, vitamin D, vitamin B-12, folate, and fatty acid status)?

206 Among those with low vitamin B-12, high UMFA or high serum total folate was a

207 Among those with "normal" vitamin B-12, higher UMFA or serum total folate was prot

208 12 status was assessed with the use of total vitamin B-12, holotranscobalamin, and a composite indica

209 Treatment increased serum vitamin B-12, holotranscobalamin, and cB-12 (P < 0.001)

210 , there was no evidence of an association of vitamin B-12, holotranscobalamin, or cB-12 with any nerv

211 Serum and plasma concentrations of vitamin B-12, holotranscobalamin, total homocysteine (tH

212 whole grains, and legumes, supplemented with vitamin B-12, is nutritionally superior to diets includi

213 Vitamin B-12 status was defined by combining vitamin B-12, plasma total homocysteine (tHcy), methylma

214 significant group differences were found for vitamin B-12, retinol, linoleic acid (LA), alpha-linolen

215 A key pathway of this metabolism is the vitamin B-12- and folate-dependent remethylation of homo

216 arrier.We studied the effect of the use of a vitamin B-12-fortified toothpaste on vitamin-status mark

217 ons (especially persons aged >=70 y) who are vitamin B-12-replete and have normal renal function indi

218 centrations were considerably narrower for a vitamin B-12-replete subpopulation with normal renal fun

219 ignificantly correlated with MS activity and vitamin B-12.

220 he risks of anemia, iron deficiency, and low vitamin B-12.

221 min 2 (TCN2), which is referred to as active vitamin B-12.

222 elders with normal plasma concentrations of vitamin B-12.

223 ntrations of biomarkers in choline pathways, vitamins B-12 and A, and essential fatty acids.A randomi

224 orus, potassium, folic acid, riboflavin, and vitamins B-12, C, and E, and by approximately 25% for se

225 and zinc, while maternal and newborn folate, vitamins B-12, D, and E, zinc, and iodine biomarkers wer

226 on colorimetric analysis allow estimation of vitamin B(2) concentration in milk.

227 re performed to develop prediction models of vitamin B(2) concentration in milk.

228 Until now, there are few information on vitamin B(2) concentration variability in milk.

229 ethod to enable enhancement of researches on vitamin B(2) content of milk and its variation factors.

230 a novel analytical method to quantify total vitamin B(2) in milk was developed and applied on 676 sa

231 an acid and enzymatic extraction followed by vitamin B(2) quantification by Ultra High Performance Li

232 s metabolite antigens derived from microbial vitamin B(2) synthesis to activate mucosal-associated in

233 t energy, mass, monounsaturated fatty acids, vitamins B(3,12) and D, choline, zinc, and selenium.

234 3.198 to 5468.184 +/- 106.859 ug/Kg, wherein Vitamin B(5), B(3) and B(2) were dominant.

235 sociated with tHcy (n = 18), folate (n = 3), vitamin B(6) (n = 1), and vitamin B(12) (n = 14) levels,

236 t play a critical role in the homeostasis of vitamin B(6) and amino acids.

237 O quantum dots (QDs) were decorated with the vitamin B(6) cofactors like pyridoxal 5'-phosphate (PLP)

238 accessibility of the PL, PN, and PM forms of vitamin B(6) in baby foods is lower in both gastric pHs.

239 accessibility of the PL, PN, and PM forms of vitamin B(6) in cereal-based baby foods an in vitro dige

240 idoxine (PN), and pyridoxamine (PM) forms of vitamin B(6) is different, considering that their bioacc

241 increase in genetically predicted folate and vitamin B(6) levels were 0.49 (95% CI, 0.34-0.71; p = 1.

242 egulating human PNPOx, whose crucial role in vitamin B(6) metabolism and epilepsy is well-known.

243 ed several metabolic pathways, in particular vitamin B(6) metabolism.

244 Analyses of vitamin B(6) pools found the high-levels of pyridoxine 5

245 eukaryotes, pyridoxal kinase (PDXK) acts in vitamin B(6) salvage pathway to produce pyridoxal 5'-pho

246 In this study, the PL, PN, and PM forms of vitamin B(6) were determined using HPLC in 13 cereal-bas

247 hate (PLP), the catalytically active form of vitamin B(6), takes place through the so-called deoxyxyl

248 We also found that higher intakes of vitamin B-6 (quartile 5 compared with quartile 1: 2.62;

249 mg vitamin B-12 (which also contained 100 mg vitamin B-6 and 100 mg vitamin B-1) on vitamin B-12 stat

250 rations in Kyn metabolism when investigating vitamin B-6 and health.

251 Dietary intake of vitamin B-6 and whole grains was directly associated wit

252 We evaluated the vitamin B-6 biomarkers PLP, pyridoxal, and pyridoxic aci

253 xal + PLP) ratio (PAr), a proposed marker of vitamin B-6 catabolism during activated cellular immunit

254 Inflammatory processes, including vitamin B-6 catabolism, could explain such findings.We i

255 of follow-up between sampling and diagnosis.Vitamin B-6 deficiency as measured by plasma PLP is asso

256 estigated long-term clinical implications of vitamin B-6 deficiency in stable outpatient RTRs.In a lo

257 s were observed for graft failure (P = 0.18).Vitamin B-6 deficiency is common in RTRs and does not se

258 In RTRs, vitamin B-6 deficiency was associated with considerably

259 Vitamin B-6 deficiency was defined as PLP <20 nmol/L, an

260 ons < ~20 nmol/L, a recognized threshold for vitamin B-6 deficiency.

261 lored the association between plasma folate, vitamin B-6 in the form of pyridoxal 5'-phosphate (PLP),

262 PLP influences long-term outcome.We compared vitamin B-6 intake and circulating PLP concentrations of

263 1.8-12.1 y) after transplantation], the mean vitamin B-6 intakes in RTRs and healthy controls were 1.

264 Higher plasma concentrations of the vitamin B-6 marker pyridoxal 5'-phosphate (PLP) have bee

265 e of Kyns as potential markers of functional vitamin B-6 status across 2 large cohorts.

266 We have previously shown that vitamin B-6 status affects the kynurenine (Kyn) pathway

267 he association of plasma PLP with functional vitamin B-6 status and explored the potential associatio

268 our analyses of novel markers of functional vitamin B-6 status and vitamin B-6-associated oxidative

269 Low vitamin B-6 status has been related to increased risk of

270 uch findings.We investigated 3 biomarkers of vitamin B-6 status in relation to CRC risk.This was a pr

271 Worse functional vitamin B-6 status in RTRs is independently associated w

272 tive and specific indicator of intracellular vitamin B-6 status is obtained.

273 Vitamin B-6 status is routinely measured as pyridoxal 5'

274 thionine with lifestyle factors and impaired vitamin B-6 status on mortality need further investigati

275 n B-6-deficient RTRs have a worse functional vitamin B-6 status than do healthy controls and vitamin

276 XA ratio was used as functional biomarker of vitamin B-6 status with a higher ratio reflecting worse

277 ored the potential association of functional vitamin B-6 status with long-term mortality in RTRs.In a

278 :XA (HK:XA), an inverse marker of functional vitamin B-6 status, and PA:(PLP + pyridoxal) (PAr), a ma

279 PLP was used as direct biomarker for vitamin B-6 status, and the 3-HK:XA ratio was used as fu

280 2.14; 95% CI: 1.48, 3.08) than a sufficient vitamin B-6 status, independent of potential confounders

281 h a higher ratio reflecting worse functional vitamin B-6 status.Median PLP, 3-HK, and XA concentratio

282 nd oxidative stress and an inverse marker of vitamin B-6 status.Plasma PLP concentrations were associ

283 ntrols (47% male; age 54 +/- 11 y), baseline vitamin B-6 was measured as plasma PLP by high-performan

284 sphate (PLP; the biologically active form of vitamin B-6), and vitamin B-12 and breast cancer risk in

285 emiologic evidence regarding niacin, folate, vitamin B-6, and vitamin B-12 intake in relation to cogn

286 bumin, calcium, iron, ferritin, cholesterol, vitamin B-6, and vitamin D (data collected from 2009 thr

287 by safe and inexpensive interventions (e.g., vitamin B-6, B-9, and B-12 supplementation).

288 In contrast, thiamin, vitamin B-6, calcium, iron, and zinc had linear or quadr

289 Dietary intakes of vitamin B-6, magnesium, and zinc were below the Estimate

290 Vitamin B-6, whole grains, processed meats, and foods fr

291 markers of functional vitamin B-6 status and vitamin B-6-associated oxidative stress and inflammation

292 increment: 1.50; 95% CI: 1.21, 1.86) in RTRs.Vitamin B-6-deficient RTRs have a worse functional vitam

293 amin B-6 status than do healthy controls and vitamin B-6-sufficient RTRs.

294 B vitamins [vitamins B-6, B-9 (folate), and B-12] play important rol

295 on treatment for preserving total folates or vitamin B(9) in watercress (Nasturtium officinale R.

296 R1 can present activating and non-activating vitamin-B-based ligands to mucosal-associated invariant

297 l subset in mammals that recognize microbial vitamin B metabolites presented by the evolutionarily co

298 The antigen-presenting molecule MR1 presents vitamin B-related antigens (VitB antigens) to mucosal-as

299 hermore, concentration-dependent addition of vitamin B-related metabolite ligands of MR1 reduced TCR

300 MR1 presents vitamin B-related metabolites to mucosal associated inva

301 c association provides further evidence that vitamin B supplements are not chemopreventive for lung c

302 protein 1 (MR1) presents metabolites of the vitamin B synthesis pathways to mucosal-associated invar

303 cause of the high prevalence of supplemental vitamin B use, any possible increased association warran