ライフサイエンスコーパス: voltage-gated @1 channel

1 y to regulate the expression and activity of voltage-gated ion channels.

2 much less is known about non-domain-swapped voltage-gated ion channels.

3 d and functionally relevant genes, including voltage-gated ion channels.

4 tructural framework for activation gating in voltage-gated ion channels.

5 urrent is reminiscent of an omega current in voltage-gated ion channels.

6 nsmitter receptors to the dynamics shaped by voltage-gated ion channels.

7 tics for LQTS because they are modulators of voltage-gated ion channels.

8 assemble with and modulate the properties of voltage-gated K(+) channels.

9 ated by an influx of sodium (Na(+)) ions via voltage-gated Na(+) channels.

10 ors, including the NMDA receptor (NMDAR) and voltage-gated Na(+) channels.

11 cooperation with the orthologue of an R-type voltage-gated calcium channel.

12 ggests that BsYetJ/TMBIM6 is a pH-dependent, voltage-gated calcium channel.

13 ibution from entry through NMDA receptors or voltage-gated sodium channels.

14 utoregulatory mechanism in Ca(V)1 and Ca(V)2 voltage-gated calcium channels.

15 s in a calcium-dependent manner and binds to voltage-gated calcium channels.

16 the transient opening of different types of voltage-gated calcium channels.

17 hanisms and enter the cytosol mostly through voltage-gated calcium channels.

18 mutated hippocalcin, mostly driven by N-type voltage-gated calcium channels.

19 This is the case for voltage-gated calcium channels.

20 e proteins that can bind and modulate L-type voltage-gated calcium channels.

21 changes that led to abnormal inactivation of voltage-gated calcium channels.

22 r Ca(2+) levels due to Ca(2+) influx through voltage-gated calcium channels.

23 tial segment was only partially dependent on voltage-gated calcium channels.

24 nism that confers adrenergic modulation upon voltage-gated calcium channels.

25 by which beta-adrenergic agonists stimulate voltage-gated calcium channels.

26 ee of the four derivatives are able to block voltage-gated potassium channels.

27 study the effect of LITAF on Cav1.2 (L-type voltage-gated calcium channel 1.2) channel expression, s

28 The voltage-gated sodium channel 1.7 (Nav1.7) plays an impor

29 , in mice, this effect is mediated solely by voltage-gated sodium channel 1.8 (NaV1.8).

30 by beta-adrenergic augmentation of Ca(V)1.2 voltage-gated calcium channels(1-4).

31 -activated potassium (BK) channels and Kv3.3 voltage-gated potassium channels accompanies the inabili

32 onal models may have the possibility to link voltage-gated ion channel activation to perception thres

33 However, expression analysis of voltage-gated sodium channel alpha subunits revealed NaV

34 from the aberrant expression and activity of voltage-gated ion channels, although the identification

35 n of all deletions in the significant set of voltage-gated calcium channels among CNVs called from bo

36 ts proposed biological targets include human voltage-gated sodium channels, among other membrane prot

37 e distribution of trajectories recorded from voltage gated calcium channels and phospholipid anchored

38 ential (AP) waveform controls the opening of voltage-gated calcium channels and contributes to the dr

39 Deconditioning was mediated by L-type voltage-gated calcium channels and is consistent with co

40 be explained by the varying distributions of voltage-gated ion channels and by morphological differen

41 In voltage-gated K(+) channels and the prokaryotic KcsA cha

42 BTX targets voltage-gated Na(+) channels and enables them to open pe

43 inactivated conformational cycle in a single voltage-gated sodium channel and give insight into the s

44 rs and not through NMDA receptors or through voltage-gated sodium channels and that the spine neck is

45 MDA, GABA-A, mGluR2/3 receptors and Nav, Cav voltage-gated ion channels) and demonstrated the ability

46 ponses in each compartment were dependent on voltage-gated calcium channels, and somatic and nuclear

47 e relationship among gating modifier toxins, voltage-gated ion channels, and the lipid membrane surro

48 f the interactions between CBD and the NavMs voltage-gated sodium channel, and electrophysiology to s

49 ies in the serum (21.30 nmol/L) and P/Q-type voltage-gated calcium channel antibodies (220 pmol/L).

50 Voltage gated sodium channels are key players in aberran

51 The opening and closing of voltage-gated ion channels are regulated by voltage sens

52 st commonly used pharmacological blockers of voltage-gated ion channels are well understood; however,

53 The EAG (ether-a-go-go) family of voltage-gated K(+) channels are important regulators of

54 EAG-like (ELK) voltage-gated potassium channels are abundantly expresse

55 Kv3.1 and Kv3.2 voltage-gated potassium channels are expressed on parval

56 ABSTRACT: Voltage-gated sodium channels are critical for neuronal

57 Voltage-gated sodium channels are critical for periphera

58 Fast opening and closing of voltage-gated sodium channels are crucial for proper pro

59 ate, we provide novel evidence that multiple voltage-gated sodium channels are involved in schizophre

60 In this study, we investigated whether voltage-gated sodium channels are involved in the develo

61 Voltage-gated sodium channels are subjected to S-palmito

62 Voltage-gated sodium channels are targets for a range of

63 ich includes oscillatory calcium signals via voltage-gated calcium channels as a key component.

64 enes and their implications, with a focus on voltage-gated calcium channels as part of the disease pr

65 These K2P channels, but not voltage-gated K(+) channels as in other parts of nerves,

66 myelinating Schwann cells, such as clustered voltage-gated sodium channels at the node of Ranvier and

67 deficient for exon 1b, PV interneurons lack voltage-gated sodium channels at their axonal initial se

68 nction, resembling prokaryote single-domain, voltage-gated Na(+) channels (BacNa(v)s) [4].

69 Bacterial voltage-gated sodium channels (BacNavs) serve as models

70 The alpha(2)delta-1 subunit of voltage-gated calcium channels binds to gabapentin and p

71 We have studied the regulation of voltage-gated calcium channels by MDIMP, which disrupts

72 is a psychiatric risk gene that encodes the voltage-gated calcium channel Ca(V)1.2.

73 forming subunit of the pre-synaptic neuronal voltage-gated calcium channel Ca(v)2.2/N-type, crucial f

74 report the presence of a splice isoform of a voltage-gated calcium channel (Ca(V)1.3) in the pigeon i

75 tors juxtaposed with presynaptic ribbons and voltage-gated calcium channels (Ca(V)1.3).

76 ll biology in bystander neurons, as were the voltage-gated calcium channel Cacophony (Cac) and the mi

77 , single-channel current amplitude of native voltage-gated calcium channels can be resolved accuratel

78 Mutations in pre-synaptic voltage-gated calcium channels can lead to familial hemi

79 of known renal autoregulation mechanisms and voltage-gated calcium channels can maintain overall rena

80 results of this autaptic action affect cone voltage-gated Ca2+ channel (CaV channel) gating through

81 lease-activated calcium modulator 1 but also voltage-gated calcium channel (Cav) 1 channels.

82 Here we show that the voltage-gated calcium channel CaV1.3 and the big conduct

83 encoding the alpha1A subunit of the P/Q-type voltage-gated calcium channel Cav2.1.

84 show that FMRP binds the mRNA of the R-type voltage-gated calcium channel Cav2.3 in mouse brain syna

85 rves as a key translational regulator of the voltage-gated calcium channel Cav2.3 under basal conditi

86 n 7 patients (6.3%): 3 (2.7%) had TPO-Ab and voltage-gated potassium channel complex (VGKCc) Ab, 2 (1

87 ociated with antibodies to components of the voltage-gated potassium channel complex (VGKCC-Ab-LE) of

88 Voltage-gated sodium channels comprise an ion-selective

89 Hence, the mechanism by which voltage-gated cation channels couple conformational chan

90 Here, we recorded the voltage-gated calcium channel current in nucleated patch

91 also found alterations in the properties of voltage-gated sodium channel currents in Jedi-1 null neu

92 The results support the hypothesis that voltage-gated ion channel distributions and morphology d

93 (2020) demonstrate that Ca(v)2-type voltage-gated calcium channels do not mediate presynapti

94 in a reduction in the fraction of available voltage-gated sodium channels due to insufficient recove

95 mutations in previously unreported HVCN1, a voltage-gated proton channel-encoding gene and B-cell re

96 Voltage-gated ion channels endow membranes with excitabi

97 H caused a reduction in cacophony, a Type II voltage-gated calcium channel, expression and that genet

98 Voltage-gated ion channels feature voltage sensor domain

99 The dominant role of Ca(V)2 voltage-gated calcium channels for driving neurotransmit

100 membrane containing the vectorially oriented voltage-gated K(+) channel for the activated, open and d

101 Voltage-gated potassium channels formed by KCNQ2 and KCN

102 acids in the voltage-sensing domain of most voltage-gated ion channels, forms a constriction between

103 Voltage-gated K(+) channels function in macromolecular c

104 ity, consistent with increased expression of voltage-gated potassium channel gene Kcna1 and decreased

105 n Culex quinquefasciatus display CNV for the voltage-gated sodium channel gene (Vgsc), target-site of

106 Missense variants in the SCN8A voltage-gated sodium channel gene are linked to early-in

107 gous loss-of-function mutations in the brain voltage-gated sodium channel gene SCN1A.

108 caused by de novo missense mutations in the voltage-gated sodium channel gene SCN8A Here, we investi

109 erity have been associated with mutations in voltage-gated sodium channel genes.

110 Voltage-gated proton channels (H(V)1) are essential for

111 Here we introduce roNaV2, an engineered voltage-gated Na(+) channel harboring a selenocysteine i

112 Here, we identify a family of voltage-gated "pacemaker" channels, HCNL1, that are exqu

113 ovement may occur during gating of the human voltage-gated proton channel, hH(V)1, but proton current

114 The human voltage-gated sodium channel, hNa(V)1.5, is responsible

115 The voltage-gated proton channel Hv1 is a member of the volt

116 The voltage-gated proton channel Hv1 regulates proton fluxes

117 In contrast to most voltage-gated ion channels, hyperpolarization- and cAMP

118 Voltage-gated Na(+) channel ( I(Na)) function is critica

119 LGI1-IgG-positive specimens had higher voltage-gated potassium channel-IgG immunoprecipitation

120 iomyocytes demonstrated that the anti-L-type voltage-gated calcium channel immunoglobulin G purified

121 receptor 2 (mGluR2) signaling, which acts on voltage-gated calcium channels in SACs, selectively rest

122 sential for estimating numbers of functional voltage-gated calcium channels in the membrane and the s

123 ependent on the presence of apically located voltage-gated cation channels in a population of electro

124 STATEMENT Changes in dendritic function, and voltage-gated ion channels in particular, are increasing

125 Rather, it is mediated by voltage-gated ion channels in the cone membrane and acts

126 eactivated, closed states of three different voltage-gated K(+) channels in hydrated phospholipid bil

127 tide from the Leiurus scorpion venom, blocks voltage-gated K(+)-channels in a unique example of bindi

128 oincident signals depends on the presence of voltage-gated Na(+) channels in the spine head, while NM

129 ty of the VLS, we analyzed the expression of voltage-gated potassium channels in rodent and primate b

130 A SIGNIFICANCE STATEMENT Na(v)1.6 is a major voltage-gated sodium channel in human brain, where it re

131 f variants in SCN5A, which encodes the major voltage-gated sodium channel in the heart.

132 Na(v)1.6 (SCN8A) is a major voltage-gated sodium channel in the mammalian CNS, and i

133 Na(v)1.7 and other voltage-gated sodium channels in mouse DRG are considere

134 tricular action potential depends on several voltage-gated ion channels, including Na(V), Ca(V), and

135 now linked multiple human pain disorders to voltage-gated sodium channels, including disorders chara

136 ons in the ryanodine receptor but not in the voltage-gated calcium channel, indicating that these phe

137 , there is a dose-dependent effect of L-type voltage gated calcium channel inhibitors on synchronous

138 Voltage-gated sodium channels initiate electrical signal

139 nalogues vary in their selectivity for human voltage-gated ion channels involved in the ventricular a

140 The opening of voltage-gated ion channels is initiated by transfer of g

141 Conductance in voltage-gated ion channels is regulated by membrane volt

142 The Nav1.1 voltage-gated sodium channel is a critical contributor t

143 The voltage-gated sodium channel is critical for cardiomyocy

144 The NaV1.7 voltage-gated sodium channel is implicated in human pain

145 congenital insensitivity to pain (CIP); this voltage-gated sodium channel is therefore a key target f

146 Nav1.6 is the primary voltage-gated sodium channel isoform expressed in mature

147 The voltage-gated sodium channel isoform Na(V)1.7 is highly

148 at, while VPA is capable of binding to these voltage-gated sodium channels, it has a very different m

149 ovo missense variant in KCNA2, which encodes voltage-gated K(+) channel K(V) 1.2.

150 Pathogenic variants in KCNB1, encoding the voltage-gated potassium channel K(V) 2.1, are associated

151 eptor channel P2X purinoceptor 7 (P2X7), the voltage-gated potassium channel K(V)1.3 and the voltage-

152 hairpinin scaffold, which selectively blocks voltage-gated potassium channels K(v)1.3.

153 Aminopyridine (4AP) is a specific blocker of voltage-gated potassium channels (K(V)1 family) clinical

154 Voltage-gated potassium channels (K(v)s) are gated by tr

155 tion were linked to faster inactivation of a voltage-gated potassium channel, K(v)1.4.

156 Neuronal voltage-gated potassium channels (Kv) are critical regul

157 oss-of-function or a gain-of-function of the voltage-gated K+ channel Kv1.2, were described to cause

158 sine RNA editing in transcripts encoding the voltage-gated potassium channel Kv1.1 converts an isoleu

159 The gene encoding the voltage-gated potassium channel Kv1.1, KCNA1, was codon

160 for conditions treatable by blockade of the voltage-gated potassium channel Kv1.3.

161 The voltage-gated potassium channel Kv1.5 plays important ro

162 undertaken to assess the functions of select voltage-gated potassium channels (Kv1, Kv2, Kv3, and Kv4

163 d functional interaction between DAT and the voltage-gated K(+) channel Kv2.1 (potassium voltage-gate

164 The voltage-gated K(+) channel Kv2.1 has been intimately lin

165 The voltage-gated K(+) channel Kv2.1 serves a major structur

166 L-type voltage-gated calcium channels (LTCCs) are implicated in

167 y, we found that BIN1 interacted with L-type voltage-gated calcium channels (LVGCCs) and that BIN1-LV

168 Kv3 voltage-gated potassium channels mediate action potentia

169 The finding of voltage-gated sodium channel mutations in small fibre ne

170 The sarcolemmal voltage gated sodium channel Na(V)1.4 conducts the key d

171 sufficiency of the SCN1A gene encoding brain voltage-gated sodium channel Na(V)1.1.

172 Mutations in the gene encoding the cardiac voltage-gated sodium channel Na(v)1.5 cause various card

173 Voltage-gated sodium channel Na(v)1.5 generates cardiac

174 tage-gated potassium channel K(V)1.3 and the voltage-gated sodium channel Na(V)1.7 as examples of tar

175 Voltage-gated sodium channel Na(V)1.7 is a genetically v

176 In humans, functional loss of the voltage-gated sodium channel Na(v)1.7 leads to pain inse

177 ansient receptor potential channel TRPA1 and voltage-gated sodium channel Na(v)1.7, that accompany al

178 SCN9A encodes the voltage-gated sodium channel Na(v)1.7, which is present

179 monstrates that two disease mutations in the voltage-gated sodium channel Na(v)1.8 that induce nocice

180 Modification of voltage-gated Na(+) channel (Na(V) ) function by intrace

181 Skeletal muscle voltage-gated Na(+) channel (Na(V)1.4) activity is subje

182 can trigger postsynaptic local activation of voltage-gated Na(+)-channels (Na(v)s), that is a spine s

183 A biophysical analysis revealed voltage-gated sodium channel (Na(V)) currents in menthol

184 Peripheral sensory neurons express multiple voltage-gated sodium channels (Na(V) ) critical for the

185 trodotoxin (TTX), a neurotoxin that binds to voltage-gated sodium channels (Na(v) proteins), arrestin

186 Voltage-gated sodium channels (Na(V)) are indispensable

187 Voltage-gated sodium channels (Na(v)s) initiate the acti

188 The axon models included a wide range of voltage-gated ion channels: Na(TTXs), Na(TTXr), Na(p), K

189 ABSTRACT: Voltage-gated sodium channel NaV 1.7 is required for acu

190 Thus, influx of Na(+) via voltage-gated Na(+) channels (NaV ) has emerged as an im

191 Voltage-gated Na(+) channels (Nav ) modulate neuronal ex

192 Voltage-gated sodium channel (NaV) mutations cause genet

193 We examined the repertoire of voltage-gated sodium channels (NaV) in fluorescence-sort

194 mans and other vertebrates, target conserved voltage-gated sodium channels (NaV) of nerve and muscle,

195 and whether human SAN excitability requires voltage-gated sodium channels (Nav) remains controversia

196 ic tension, the thermal random motion of the voltage-gated sodium channels (Nav), which are bound to

197 by de novo gain-of-function mutations in the voltage-gated Na channel Nav1.6.

198 of an adjacent gene (SCN2A) coding for human voltage-gated sodium channel NaV1.2 (P = 9 x 10(-4)).

199 Mutations in SCN2A, a gene encoding the voltage-gated sodium channel Nav1.2, have been associate

200 ed a critical role for the regulation of the voltage-gated sodium channel NaV1.5 in the heart by the

201 We investigated the effect of LITAF on the voltage-gated sodium channel Nav1.5, which is critical f

202 ates that the expression and function of the voltage-gated sodium channel Nav1.7 are increased in a p

203 Human genetic studies have implicated the voltage-gated sodium channel NaV1.7 as a therapeutic tar

204 Gain-of-function mutations of voltage-gated sodium channel Nav1.7 underlie dorsal root

205 ies have confirmed an important role for the voltage-gated sodium channel Nav1.9 in human pain disord

206 nsfer (LRET) between the rat skeletal muscle voltage-gated sodium channel (Nav1.4) and fluorescently

207 Gain-of-function mutations in the voltage-gated sodium channel (Nav1.5) are associated wit

208 c evidence has clearly demonstrated that the voltage-gated sodium channel, Nav1.7, is critical to pai

209 Mutations in voltage-gated sodium channels (Navs) can cause alteratio

210 Voltage-gated sodium channels (Navs) play crucial roles

211 Voltage-gated sodium channels (Navs) play essential role

212 rom Nematostella vectensis use a specialized voltage-gated calcium channel (nCa(V)) to distinguish sa

213 e, we found that the alpha2delta2 subunit of voltage-gated calcium channels negatively regulates axon

214 Ca(2+)- and voltage-gated K(+) channels of large conductance (BK cha

215 Voltage-gated potassium channels of the KCNQ (Kv7) subfa

216 synapses), the glutamate transporter, and a voltage-gated calcium channel, or if ASP cells lacked Sy

217 at paralog-conserved sites were enriched in voltage-gated sodium channels, particularly the alpha su

218 Voltage-gated ion channels play important roles in physi

219 Voltage-gated sodium channels play a critical role in ce

220 The distinct ensembles of voltage-gated ion channels predicted to underlie the uni

221 In contrast, blocking the T-type or L-type voltage-gated calcium channel promoted the spontaneous c

222 this was attributable to interdependence of voltage-gated potassium channel properties.

223 id bilayer containing a vectorially oriented voltage-gated K(+) channel protein at high in-plane dens

224 these single membranes were dominated by the voltage-gated K(+) channel protein because of the high i

225 Presynaptic alpha(2)delta subunits of voltage-gated calcium channels regulate channel abundanc

226 psychiatric disorders.SIGNIFICANCE STATEMENT Voltage-gated calcium channels regulate important neuron

227 The Kv4 family of A-type voltage-gated K(+) channels regulates the excitability i

228 ry and inhibitory cell types, genes encoding voltage-gated ion channels responsible for depolarizing

229 molecular methods to determine how Kv3.4, a voltage-gated K(+) channel robustly expressed in dorsal

230 tiated and propagated by a single isoform of voltage gated sodium channels - SCN5A.

231 We show that currents mediated by the voltage-gated potassium channels Shaw (Kv3) and Shal (Kv

232 of organic cation selectivity of eukaryotic voltage-gated sodium channels showed a sharp size cut-of

233 The voltage-gated potassium channel subfamily A member 3 (Kv

234 Neuronal voltage-gated potassium channel subfamily Q (KCNQ) dysfu

235 e the measurement of the potency of block of voltage-gated potassium channel subtype 11.1 (K(v)11.1)

236 ilayer affinity and in vitro activity at the voltage-gated sodium channel subtype 1.7 (Na(V)1.7), a c

237 Specifically, voltage-gated sodium channel subtype NaV 1.7 is required

238 Gene mutations in L-type voltage gated calcium channel subunit genes are strongly

239 ched comparison subjects as well as aberrant voltage-gated calcium channel subunit protein expression

240 The effect of increased voltage-gated calcium channel subunit protein expression

241 mechanical allodynia by regulating auxiliary voltage-gated calcium channel subunits alpha2delta-1 and

242 They belong to the voltage-gated ion channel superfamily but their activiti

243 -gated proton channel Hv1 is a member of the voltage-gated ion channel superfamily, which stands out

244 s demonstrated for a photochromic blocker of voltage-gated potassium channels, termed CAL, and a phot

245 d cyclic nucleotide-gated (HCN) channel is a voltage-gated cation channel that mediates neuronal and

246 CLC-2 is a voltage-gated chloride channel that is widely expressed

247 Kv11.1 (hERG) is a voltage-gated potassium channel that shows very slow ion

248 glycosylation including glutamate receptors, voltage-gated calcium channels, the dopamine D2 receptor

249 med mode of action is via blockade of axonal voltage gated potassium channels, thereby enhancing cond

250 hibition: first, the action of Gbetagamma on voltage-gated calcium channels to inhibit calcium influx

251 We determined the structure of a voltage-gated sodium channel, two-pore channel 3 (TPC3),

252 P2 borrows a biophysical riff from canonical voltage-gated ion channels, using 2 gating charges found

253 However, in several voltage-gated potassium channels, using specific S4-S5(L

254 depend on NMDA receptors (nmdaLTP) or L-type voltage-gated calcium channels (vdccLTP).

255 tracellular Ca(2+) levels through the T-type voltage-gated calcium channel (VGCC) and mobilization of

256 Genetic polymorphisms of the L-type voltage-gated calcium channel (VGCC) are associated with

257 bicistronic expression may be common to the voltage-gated calcium channel (VGCC) gene family and may

258 he final coding exon (exon 47) of the Cav2.1 voltage-gated calcium channel (VGCC) gene produces two m

259 ddition to Gbetagamma-mediated modulation of voltage-gated calcium channels (VGCC), inhibition can al

260 ar calcium involves purinergic receptors and voltage-gated calcium channels (VGCC).

261 t for gating currents is well documented for voltage-gated cation channels (VGCC), and it is consider

262 ACh release is supported by P/Q- and N-type voltage-gated calcium channels (VGCCs) and negatively re

263 For example, presynaptic voltage-gated calcium channels (VGCCs) and postsynaptic

264 that pharmacological manipulation of L-type voltage-gated calcium channels (VGCCs) and purinoceptors

265 Here, we show that voltage-gated calcium channels (VGCCs) are critical for

266 sfer depend on the molecular organization of voltage-gated calcium channels (VGCCs) within the presyn

267 ade of NMDA-type glutamate receptors but not voltage-gated calcium channels (VGCCs), and can also be

268 te calcium current (I (Ca)) through neuronal voltage-gated calcium channels (VGCCs).

269 erties, density, and the spatial location of voltage-gated calcium channels (VGCCs).

270 ulation were mediated, in part, by dendritic voltage-gated calcium channels (VGCCs): pharmacological

271 These dimeric voltage-gated ion channel (VGIC) superfamily members hav

272 igm, placing it squarely in the framework of voltage-gated ion channel (VGIC) superfamily members in

273 Voltage-gated ion channels (VGICs) contain positively ch

274 haring a common architecture with archetypal voltage-gated ion channels (VGICs), hyperpolarization- a

275 proteins are affected as well, particularly voltage-gated ion channels (VGICs).

276 agnetic resonance imaging has linked chronic voltage-gated potassium channel (VGKC) complex antibody-

277 ies against the extracellular domains of the voltage-gated potassium channel (VGKC) complex proteins,

278 ped redefine antigenic components within the voltage-gated potassium channel (VGKC) complex.

279 In voltage-gated potassium channels (VGKC), voltage sensors

280 vates voltage-gated Ca(2+) channels (VGCCs), voltage-gated K(+) channels (VGKCs), and Ca(2+)-activate

281 osequencing genotyping and sequencing of the voltage gated sodium channel (VGSC) gene did not detect

282 Voltage-gated sodium channel (VGSC) beta1 subunits are m

283 Veratridine (VTD) is a voltage-gated sodium channel (VGSC) modifier that is use

284 Voltage-gated sodium channel (VGSC) mutations cause seve

285 ecent genetic studies have linked pathogenic voltage-gated sodium channel (VGSC) variants to human pa

286 Voltage-gated sodium channels (VGSC) are transmembrane p

287 We hypothesize that the voltage-gated sodium channels (VGSC) on the dorsal root

288 Notably, voltage-gated sodium channels (VGSC) that are crucial fo

289 agnitude shorter than the activation time of voltage-gated sodium channels (VGSC) would evoke action

290 that eliminated the onset response by moving voltage-gated Na+ channels (VGSCs) to closed-state inact

291 KCNQ2/3 (Kv7.2/7.3) channels and voltage-gated sodium channels (VGSCs) are enriched in th

292 ree-dimensional structure of the human KCNQ1 voltage-gated potassium channel VSD in the intermediate

293 tibody against the pore domain of the L-type voltage-gated calcium channel was consistently identifie

294 re, we demonstrated that microglial Kv1.3, a voltage-gated potassium channel, was transcriptionally u

295 ity filter landscape in a mutant that mimics voltage-gated K(+) channels, which provides a foundation

296 FXS field has thus far focused primarily on voltage-gated ion channels, while contributions from vol

297 Hv1 is a voltage-gated proton channel whose main function is to f

298 KCNE3 (MiRP2) forms heteromeric voltage-gated K(+) channels with the skeletal muscle-exp

299 on that directly predicted the response of a voltage-gated K(+) channel within a phospholipid bilayer

300 (2+) entry because of synaptic activation of voltage-gated Na(+) channels within the spine.