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1 gnal from the RyR1 facilitates gating of the voltage-gated calcium channel.
2 acket (stj), an alpha(2)delta subunit of the voltage-gated calcium channel.
3 between the sigma-1 receptor and the L-type voltage-gated calcium channel.
4 g at sites in a transcript encoding a muscle voltage-gated calcium channel.
5 cooperation with the orthologue of an R-type voltage-gated calcium channel.
6 ggests that BsYetJ/TMBIM6 is a pH-dependent, voltage-gated calcium channel.
7 scription of these proteins as regulators of voltage gated calcium channels.
8 lta2 modulates the abundance and function of voltage-gated calcium channels.
9 mechanisms of direct G protein inhibition of voltage-gated calcium channels.
10 s, including subunits of GABAA receptors and voltage-gated calcium channels.
11 changes that led to abnormal inactivation of voltage-gated calcium channels.
12 kisspeptin neurons via a mechanism involving voltage-gated calcium channels.
13 ependent upon apoptotic calcium release from voltage-gated calcium channels.
14 ta3 modulates the expression and function of voltage-gated calcium channels.
15 r Ca(2+) levels due to Ca(2+) influx through voltage-gated calcium channels.
16 become widely used as an inhibitor of Cav2.3 voltage-gated calcium channels.
17 he spinal dorsal horn, via the inhibition of voltage-gated calcium channels.
18 synapse formation, dendritic morphology, and voltage-gated calcium channels.
19 tial segment was only partially dependent on voltage-gated calcium channels.
20 receptors and subsequently inhibiting CaV2.2 voltage-gated calcium channels.
21 ned, and it was inhibited by blocking L-type voltage-gated calcium channels.
22 ane proteins that includes gamma-subunits of voltage-gated calcium channels.
23 epends on the activation of T- and/or L-type voltage-gated calcium channels.
24 nism that confers adrenergic modulation upon voltage-gated calcium channels.
25 aracterized ICK-motif peptidic antagonist of voltage-gated calcium channels.
26 directly influencing the activity of L-type voltage-gated calcium channels.
27 etinal sensitivity through the modulation of voltage-gated calcium channels.
28 t chloride-mediated depolarization activates voltage-gated calcium channels.
29 , and this could be independent of ASICs and voltage-gated calcium channels.
30 icle fusion, also interacts with presynaptic voltage-gated calcium channels.
31 well known inhibition of Ca2+ entry through voltage-gated calcium channels.
32 by which beta-adrenergic agonists stimulate voltage-gated calcium channels.
33 (alpha(2)-delta) subunits (Type 1 and 2) of voltage-gated calcium channels.
34 were dependent on activation of postsynaptic voltage-gated calcium channels.
35 utoregulatory mechanism in Ca(V)1 and Ca(V)2 voltage-gated calcium channels.
36 hanisms and enter the cytosol mostly through voltage-gated calcium channels.
37 s in a calcium-dependent manner and binds to voltage-gated calcium channels.
38 the transient opening of different types of voltage-gated calcium channels.
39 mutated hippocalcin, mostly driven by N-type voltage-gated calcium channels.
40 This is the case for voltage-gated calcium channels.
41 e proteins that can bind and modulate L-type voltage-gated calcium channels.
42 seases, both genetic and acquired, involving voltage-gated calcium channels.
44 study the effect of LITAF on Cav1.2 (L-type voltage-gated calcium channel 1.2) channel expression, s
46 vern this unreliability include a paucity of voltage-gated calcium channels, a low probability of cal
47 e omega-hexatoxin-Hv1a (Hv1a) targets insect voltage-gated calcium channels, acting directly at sites
48 presynaptic action potentials (APs) activate voltage-gated calcium channels, allowing calcium to ente
50 ss typical presynaptic proteins, including a voltage-gated calcium channel (alpha1A), neural cell adh
51 criptional regulator of photoreceptor L-type voltage-gated calcium channel alpha1C subunit (L-VGCCalp
52 n of all deletions in the significant set of voltage-gated calcium channels among CNVs called from bo
53 nd 1 altering Ile770) in CACNA1D, encoding a voltage-gated calcium channel, among 43 APAs without mut
54 e distribution of trajectories recorded from voltage gated calcium channels and phospholipid anchored
55 y involving depolarization activating L-type voltage-gated calcium channels and a Ca-dependent kinase
57 terns are regulated by the interplay between voltage-gated calcium channels and calcium-sensitive pot
58 ential (AP) waveform controls the opening of voltage-gated calcium channels and contributes to the dr
59 gh affinity to the alpha(2)-delta subunit of voltage-gated calcium channels and is a substrate of the
61 nter cells via nontraditional routes such as voltage-gated calcium channels and N-methyl-d-aspartate
62 in synaptic function, and it is dependent on voltage-gated calcium channels and presynaptic calcium s
63 gh N-methyl-D-aspartate receptors and L-type voltage-gated calcium channels and requires the activity
64 re mediated by calcium influx through L-type voltage-gated calcium channels and ryanodine receptor-in
65 dies (most commonly targeting P/Q- or N-type voltage-gated calcium channels); and 15 patients, for an
66 or temporally patterned electrical activity, voltage-gated calcium channels, and CaMKII in modulating
67 equires activation of NMDA receptors, L-type voltage-gated calcium channels, and dendritic spikes.
68 ve alternative splicing, much like the other voltage-gated calcium channels, and employed the transcr
69 ragile X mental retardation protein complex, voltage-gated calcium channels, and genes implicated in
70 pha2delta proteins are auxiliary subunits of voltage-gated calcium channels, and influence their traf
71 of ionotropic glutamate receptors and L-type voltage-gated calcium channels, and is dependent on down
72 ponses in each compartment were dependent on voltage-gated calcium channels, and somatic and nuclear
73 , which causes the depolarization, activates voltage-gated calcium channels, and ultimately elevates
74 ies in the serum (21.30 nmol/L) and P/Q-type voltage-gated calcium channel antibodies (220 pmol/L).
77 found that protein kinase A (PKA) and L-type voltage-gated calcium channels are crucial for the expre
85 ated almost entirely through Cav2.2 (N-type) voltage-gated calcium channels as blocking these channel
86 enes and their implications, with a focus on voltage-gated calcium channels as part of the disease pr
92 ese GABAergic neurons was not altered by the voltage-gated calcium channel blocker cadmium chloride t
93 in glutamatergic mEPSC was unaltered by the voltage-gated calcium channel blocker cadmium, and was a
95 xtual fear memory reactivation by the L-type voltage-gated calcium channel blocker nimodipine interfe
96 ens were blocked by targeted delivery of the voltage-gated calcium channel blocker omega-conotoxin GV
97 ven when the medium contains nitrendipine, a voltage-gated calcium channel blocker, but fails to occu
101 (CaM) with the IQ-recognition motif from the voltage-gated calcium channel Ca(v)1.2 (IQ), which adopt
104 forming subunit of the pre-synaptic neuronal voltage-gated calcium channel Ca(v)2.2/N-type, crucial f
106 report the presence of a splice isoform of a voltage-gated calcium channel (Ca(V)1.3) in the pigeon i
107 gnals produced by pH-sensitive activation of voltage-gated calcium channels (Ca channels) in photorec
110 P/Q-type Ca(2+) currents through presynaptic voltage-gated calcium channels (Ca(V)2.1) by binding of
113 Precise regulation of N-type (Ca(V)2.2) voltage-gated calcium channels (Ca-channels) controls ma
114 Leaner mice with a mutation in the P/Q-type voltage-gated calcium channel, Cacna1a, develop cerebell
115 ll biology in bystander neurons, as were the voltage-gated calcium channel Cacophony (Cac) and the mi
116 function, we show that reduced levels of the voltage-gated calcium channel, cacophony, mediate some o
118 , single-channel current amplitude of native voltage-gated calcium channels can be resolved accuratel
122 of known renal autoregulation mechanisms and voltage-gated calcium channels can maintain overall rena
123 e pore-forming alpha1A subunit of the CaV2.1 voltage-gated calcium channel, cause a number of human n
129 hysiological processes, and it is known that voltage-gated calcium channels (Cav) mediate calcium inf
130 FMRP was shown to directly interact with the voltage-gated calcium channel, Cav 2.2, and reduce its t
131 e pore-forming alpha1 subunit of the cardiac voltage-gated calcium channel Cav1.2 at Ser1928, suggest
134 ional and mechanical coupling between L-type voltage-gated calcium channels (CaV1.1) and the ryanodin
138 show that FMRP binds the mRNA of the R-type voltage-gated calcium channel Cav2.3 in mouse brain syna
139 rves as a key translational regulator of the voltage-gated calcium channel Cav2.3 under basal conditi
143 thesis that TSP4 activates its receptor, the voltage-gated calcium channel Cavalpha2delta1 subunit (C
144 rted CACNA1C (alpha 1C subunit of the L-type voltage-gated calcium channel; combined P = 7.0 x 10(-8)
145 ese resolutions) into the heteromeric L-type voltage-gated calcium channel complex volume reveals mul
147 Until recently we held the simple view that voltage-gated calcium channels consisted of an alpha1 su
148 electrical activity--mediated through L-type voltage-gated calcium channels--could suppress axon grow
151 synaptic strength was not due to changes in voltage-gated calcium channel currents or activation kin
152 requires a physical interaction between the voltage-gated calcium channel dihydropyridine receptor (
153 al muscle excitation-contraction coupling, a voltage-gated calcium channel directly activates opening
155 that produce delayed inactivation of Cav1.2 voltage-gated calcium channels during cellular action po
156 tion via GABA type A receptor activation and voltage-gated calcium channels during early postnatal de
157 enerin/ENaC sodium channel MEC-4, the L-type voltage-gated calcium channel EGL-19, and the Ca/calmodu
158 H caused a reduction in cacophony, a Type II voltage-gated calcium channel, expression and that genet
159 model takes into account calcium influx via voltage-gated calcium channels, extrusion through the ce
160 f four members of the sperm-specific CATSPER voltage-gated calcium channel family known to be essenti
161 n, for a member of the low voltage-activated voltage-gated calcium channel family, CaV3.1, a T-type c
164 CACNA1C gene (alpha-1C subunit of the L-type voltage-gated calcium channel) has been identified as a
166 ls within astrocytes is controversial, these voltage-gated calcium channels have been linked to calci
168 iomyocytes demonstrated that the anti-L-type voltage-gated calcium channel immunoglobulin G purified
171 pathway stimulated by the MOR that inhibits voltage-gated calcium channels in isolated terminals fro
173 receptor 2 (mGluR2) signaling, which acts on voltage-gated calcium channels in SACs, selectively rest
174 sential for estimating numbers of functional voltage-gated calcium channels in the membrane and the s
175 ell into the IQ domain portion of the Cav1.2 voltage-gated calcium channel, indicating a potential ro
176 ons in the ryanodine receptor but not in the voltage-gated calcium channel, indicating that these phe
177 dephosphorylation was prevented by blocking voltage-gated calcium channels, indicating that distinct
178 , there is a dose-dependent effect of L-type voltage gated calcium channel inhibitors on synchronous
179 stic view that second messenger signaling to voltage-gated calcium channels involved mainly phosphory
180 nding protein 1 (CaBP1) to the CaV1 (L-type) voltage-gated calcium channel IQ domain endows the chann
183 In summary, each vertebrate gene family for voltage-gated calcium channels is represented by a singl
184 ce that the alpha(2)-delta Type 1 subunit of voltage-gated calcium channels is the major binding prot
189 onin norepinephrine reuptake inhibitors, and voltage-gated calcium channel ligands in the treatment o
191 als across cell junctions and in stimulating voltage-gated calcium channels located in T tubules.
192 a C-terminal fragment of Ca(V)1.2, an L-type voltage-gated calcium channel (LTC), translocates to the
196 y, we found that BIN1 interacted with L-type voltage-gated calcium channels (LVGCCs) and that BIN1-LV
198 fects and suggest the cAMP pathway or L-type voltage-gated calcium channels may be viable targets for
200 which stimulates adenylyl cyclase and L-type voltage-gated calcium channels, may be one intracellular
201 rom Nematostella vectensis use a specialized voltage-gated calcium channel (nCa(V)) to distinguish sa
202 e, we found that the alpha2delta2 subunit of voltage-gated calcium channels negatively regulates axon
205 (AHPs) that were insensitive to blockade of voltage-gated calcium channels or chelation of intracell
207 were not dependent on calcium influx through voltage-gated calcium channels or on calcium mobilizatio
208 ium influx but did not require activation of voltage-gated calcium channels or presynaptic NMDA recep
210 mium (100 microM, a nonselective blocker for voltage-gated calcium channels), or a medium containing
211 synapses), the glutamate transporter, and a voltage-gated calcium channel, or if ASP cells lacked Sy
212 abolished by blockade of alpha4beta2 nAChRs, voltage-gated calcium channels, or intracellular calcium
215 In contrast, blocking the T-type or L-type voltage-gated calcium channel promoted the spontaneous c
219 psychiatric disorders.SIGNIFICANCE STATEMENT Voltage-gated calcium channels regulate important neuron
223 h affinity for the alpha(2)-delta subunit of voltage-gated calcium channels, several novel beta-amino
226 e disorder in animal models suggest that the voltage-gated calcium channel subtype Ca(V)1.3 has a rol
229 Neuron, Tedeschi et al. (2016) describe the voltage-gated calcium channel subunit alpha2delta2 as a
230 ched comparison subjects as well as aberrant voltage-gated calcium channel subunit protein expression
232 mechanical allodynia by regulating auxiliary voltage-gated calcium channel subunits alpha2delta-1 and
233 es between voltage-gated sodium channels and voltage-gated calcium channels suggest that the structur
234 It has been established that Ca(V)3.2 T-type voltage-gated calcium channels (T-channels) play a key r
235 ng human CaV3.3 alpha1 subunit, a subtype of voltage-gated calcium channel that contributes to T-type
236 g the Ca(v)2.1alpha1 subunit of the P/Q-type voltage-gated calcium channel that result in an overall
237 alpha2delta-1 is an auxiliary subunit of voltage-gated calcium channels that affects calcium-chan
238 he mechanism of dopamine activation requires voltage-gated calcium channels that are also present at
239 e-2 (EA2) is caused by mutations in P/Q-type voltage-gated calcium channels that are expressed at hig
240 n isolated by blockade of NMDA receptors and voltage-gated calcium channels, the absence of both tran
241 glycosylation including glutamate receptors, voltage-gated calcium channels, the dopamine D2 receptor
243 did treatment with nicardipine, which blocks voltage-gated calcium channels through which zinc enters
244 hibition: first, the action of Gbetagamma on voltage-gated calcium channels to inhibit calcium influx
245 y fiber terminals leverage distinct types of voltage-gated calcium channels to mediate short-term fac
246 les, and reduced fusion triggered by opening voltage-gated calcium channels under voltage clamp, with
247 mal motile cilia is not tightly regulated by voltage-gated calcium channels, unlike that of well-stud
249 tional flat surfaces may exhibit exaggerated voltage gated calcium channel (VGCC) functionality.
250 ptor potential vanilloid (TRPV) 4 and L-type voltage-gated calcium channel (VGCC) and an increase in
251 tracellular Ca(2+) levels through the T-type voltage-gated calcium channel (VGCC) and mobilization of
252 lves two major calcium-binding proteins, the voltage-gated calcium channel (VGCC) and the vesicular p
254 he baldness associated with mutations in the voltage-gated calcium channel (VGCC) Cav1.2 underlying T
255 al for exocytosis, also controls presynaptic voltage-gated calcium channel (VGCC) function dictating
256 ed we report that HFS persistently depresses voltage-gated calcium channel (VGCC) function in Fil ter
257 f cell types has shown that Rem2 can inhibit voltage-gated calcium channel (VGCC) function, while stu
258 bicistronic expression may be common to the voltage-gated calcium channel (VGCC) gene family and may
259 he final coding exon (exon 47) of the Cav2.1 voltage-gated calcium channel (VGCC) gene produces two m
261 located in an intronic region of the L-type voltage-gated calcium channel (VGCC) subunit gene CACNA1
262 ac encodes an alpha1 subunit of a Drosophila voltage-gated calcium channel (VGCC) that is required fo
263 emphasized the importance of the T-type low-voltage-gated calcium channels (VGCC) in different cance
265 ddition to Gbetagamma-mediated modulation of voltage-gated calcium channels (VGCC), inhibition can al
268 : N-methyl-d-aspartic acid (NMDA) receptors, voltage gated calcium channels (VGCCs), neuronal nitric
270 allow somatic action potentials to activate voltage-gated calcium channels (VGCCs) along the entire
271 fied their ability to activate L- and N-type voltage-gated calcium channels (VGCCs) and delineated th
272 ACh release is supported by P/Q- and N-type voltage-gated calcium channels (VGCCs) and negatively re
274 that pharmacological manipulation of L-type voltage-gated calcium channels (VGCCs) and purinoceptors
275 ised [Ca(2+)](i), mediated by influx through voltage-gated calcium channels (VGCCs) and release from
276 resynaptic activity, postsynaptic potential, voltage-gated calcium channels (VGCCs) and UNC-43, the C
280 , as observed at all other synapses studied, voltage-gated calcium channels (VGCCs) couple membrane d
283 tivity-dependent potentiation of presynaptic voltage-gated calcium channels (VGCCs) underlies 3,4-dia
284 Reducing calcium influx by blocking R-type voltage-gated calcium channels (VGCCs) with Ni(2+), or b
285 ere, we show that chronic blockade of L-type voltage-gated calcium channels (VGCCs) with nifedipine d
286 sfer depend on the molecular organization of voltage-gated calcium channels (VGCCs) within the presyn
287 ade of NMDA-type glutamate receptors but not voltage-gated calcium channels (VGCCs), and can also be
288 vity depend critically on proper function of voltage-gated calcium channels (VGCCs), whose activity m
294 ulation were mediated, in part, by dendritic voltage-gated calcium channels (VGCCs): pharmacological
295 In contrast, whereas CP55,940 inhibited voltage-gated calcium channels via CB(2) receptor activa
296 tibody against the pore domain of the L-type voltage-gated calcium channel was consistently identifie
299 thus suggest a selective coupling of N-type voltage-gated calcium channels with calcium-activated po
300 ts the identity and cellular distribution of voltage-gated calcium channels within dopaminergic neuro