ライフサイエンスコーパス: voltage-gated sodium channel

1 n (c.4447G>A; p.E1483K) in SCN8A, encoding a voltage-gated sodium channel.

2 ic causes are mutations in Nav1.1 (SCN1A), a voltage-gated sodium channel.

3 rom wild-type and epilepsy-associated mutant voltage-gated sodium channels.

4 latus that delays inactivation of vertebrate voltage-gated sodium channels.

5 between activation and fast inactivation in voltage-gated sodium channels.

6 ing p38 MAPK-mediated negative modulation of voltage-gated sodium channels.

7 and fails to recruit neurofascin as well as voltage-gated sodium channels.

8 in the immature brain through alteration of voltage-gated sodium channels.

9 clusters for gliomedin, neurofascin-186, and voltage-gated sodium channels.

10 ibution from entry through NMDA receptors or voltage-gated sodium channels.

11 om tarantula venom able to inhibit the human voltage-gated sodium channel 1.7 (hNaV1.7), a channel re

12 The prominent role of voltage-gated sodium channel 1.7 (Nav1.7) in nociception

13 The voltage-gated sodium channel 1.7 (Nav1.7) plays an impor

14 ipheral expression of tetrodotoxin-resistant voltage-gated sodium channel 1.8 (NaV1.8) has been shown

15 , in mice, this effect is mediated solely by voltage-gated sodium channel 1.8 (NaV1.8).

16 The location of the gate in voltage-gated sodium channels, a founding member of this

17 Cone snail toxins are well known blockers of voltage-gated sodium channels, a property that is of bro

18 g shift of tetrodotoxin-sensitive persistent voltage-gated sodium channel activation.

19 annels, Kir2.1 and dORKDelta-C) or decreased voltage-gated sodium channel activity (using mutations i

20 NRG1 are primarily attributable to decreased voltage-gated sodium channel activity, as current densit

21 maging in rat slices, we find that dendritic voltage-gated sodium channels allow somatic action poten

22 The mutations in the coding region of voltage-gated sodium channel alpha 1 subunit gene, SCN1A

23 However, expression analysis of voltage-gated sodium channel alpha subunits revealed NaV

24 a2-subunits in the ventricle is to chaperone voltage-gated sodium channel alpha-subunits to the plasm

25 ts proposed biological targets include human voltage-gated sodium channels, among other membrane prot

26 inactivated conformational cycle in a single voltage-gated sodium channel and give insight into the s

27 sity accommodate the atomic coordinates of a voltage-gated sodium channel and of the beta subunit in

28 lication of thrombin did not alter transient voltage-gated sodium channels and action potential thres

29 te loss of nodal protein staining, including voltage-gated sodium channels and ankyrin G, occurs and

30 enous cannabinoids have been shown to target voltage-gated sodium channels and cannabidiol has recent

31 but allosterically coupled receptor sites on voltage-gated sodium channels and cause persistent chann

32 n II and to the pore module of domain III in voltage-gated sodium channels and enhance channel activa

33 s required for the interaction of FGF14 with voltage-gated sodium channels and neuronal excitability.

34 rs and not through NMDA receptors or through voltage-gated sodium channels and that the spine neck is

35 led the peptide's putative molecular target (voltage-gated sodium channels) and mechanism of action (

36 f the interactions between CBD and the NavMs voltage-gated sodium channel, and electrophysiology to s

37 eurofascin, neuronal cell adhesion molecule, voltage-gated sodium channels, and actin filaments.

38 ts, at least in part, through its actions on voltage-gated sodium channels, and resurgent current may

39 urons, which express a unique combination of voltage-gated sodium channels; and (3) heterologously ex

40 Voltage gated sodium channels are key players in aberran

41 Mammalian voltage-gated sodium channels are composed of four homol

42 Voltage-gated sodium channels are critical determinants

43 ABSTRACT: Voltage-gated sodium channels are critical for neuronal

44 Voltage-gated sodium channels are critical for periphera

45 Activation and inactivation of voltage-gated sodium channels are critical for proper el

46 Voltage-gated sodium channels are crucial determinants o

47 Fast opening and closing of voltage-gated sodium channels are crucial for proper pro

48 Voltage-gated sodium channels are essential for electric

49 Voltage-gated sodium channels are important targets for

50 Voltage-gated sodium channels are inhibited by many loca

51 ate, we provide novel evidence that multiple voltage-gated sodium channels are involved in schizophre

52 In this study, we investigated whether voltage-gated sodium channels are involved in the develo

53 Voltage-gated sodium channels are required for the initi

54 Voltage-gated sodium channels are responsible for action

55 Voltage-gated sodium channels are subjected to S-palmito

56 Voltage-gated sodium channels are targets for a range of

57 However, when voltage-gated sodium channels are temporarily blocked, c

58 Voltage-gated sodium channels are the primary target of

59 The mechanism by which voltage-gated sodium channels are trafficked to the surf

60 Voltage-gated sodium channels are vital membrane protein

61 Variants in SCN10A, which encodes a voltage-gated sodium channel, are associated with altera

62 muscle channel (SCN4A), encoding the Nav1.4 voltage-gated sodium channel, are causative of a variety

63 These results show that BBG inhibits voltage-gated sodium channels at micromolar concentratio

64 l isoform of Neurofascin, Nfasc186, clusters voltage-gated sodium channels at nodes of Ranvier in mye

65 myelinated nerves requires the clustering of voltage-gated sodium channels at nodes of Ranvier.

66 myelinating Schwann cells, such as clustered voltage-gated sodium channels at the node of Ranvier and

67 deficient for exon 1b, PV interneurons lack voltage-gated sodium channels at their axonal initial se

68 e secretases also regulate the processing of voltage-gated sodium channel auxiliary beta-subunits and

69 GIC behavior, we addressed how the bacterial voltage-gated sodium channel (BacNa(V)) C-terminal cytop

70 es of members of a large family of bacterial voltage-gated sodium channels (BacNa(V)s) prevalent in s

71 Bacterial voltage-gated sodium channels (BacNavs) serve as models

72 omologous factors (FHFs) bound to axosomatic voltage-gated sodium channels bear an N-terminal blockin

73 Identified genes included voltage-gated sodium channel beta subunits, potassium ch

74 Mutations in SCN2B, encoding voltage-gated sodium channel beta2-subunits, are associa

75 nts revealed that Ae1a potently inhibits the voltage-gated sodium channel BgNaV1 from the German cock

76 teractions between scaffolding molecules and voltage-gated sodium channels, but the molecular mechani

77 tion, pyridine nucleotides also modulate the voltage-gated sodium channel by supporting the activity

78 f cone snails, known as mu-conotoxins, block voltage-gated sodium channels by physically occluding th

79 Key among them is the voltage-gated sodium channel complex.

80 Voltage-gated sodium channels comprise an ion-selective

81 also found alterations in the properties of voltage-gated sodium channel currents in Jedi-1 null neu

82 des (P<0.0001), with altered architecture of voltage-gated sodium channel distribution.

83 in a reduction in the fraction of available voltage-gated sodium channels due to insufficient recove

84 polychlorocyclohexanes and fiproles, and the voltage-gated sodium channel for pyrethroids and dichlor

85 complexes often considered independent: the voltage-gated sodium channel, gap junctions, and the car

86 T. urticae populations and a mutation in the voltage-gated sodium channel gene (F1538I) in 66.7% popu

87 n Culex quinquefasciatus display CNV for the voltage-gated sodium channel gene (Vgsc), target-site of

88 Missense variants in the SCN8A voltage-gated sodium channel gene are linked to early-in

89 gous loss-of-function mutations in the brain voltage-gated sodium channel gene SCN1A.

90 De novo mutations of the voltage-gated sodium channel gene SCN8A have recently be

91 caused by de novo missense mutations in the voltage-gated sodium channel gene SCN8A Here, we investi

92 eased in number in larvae that have a mutant voltage-gated sodium channel gene, scn8aa.

93 e mutation (c.5302A>G [p.Asn1768Asp]) in the voltage-gated sodium-channel gene SCN8A in the proband.

94 erity have been associated with mutations in voltage-gated sodium channel genes.

95 Although a gate residue in the eukaryotic voltage-gated sodium channel has been identified, the mi

96 Slow inactivation of voltage-gated sodium channels has been discussed to be t

97 The activity of voltage-gated sodium channels has long been linked to di

98 Mutations in brain isoforms of voltage-gated sodium channels have been identified in pa

99 Voltage-gated sodium channels have essential roles in el

100 The human voltage-gated sodium channel, hNa(V)1.5, is responsible

101 alanine 1486 (F1486del) in the human cardiac voltage-gated sodium channel (hNav1.5) is associated wit

102 A SIGNIFICANCE STATEMENT Na(v)1.6 is a major voltage-gated sodium channel in human brain, where it re

103 f variants in SCN5A, which encodes the major voltage-gated sodium channel in the heart.

104 Na(v)1.6 (SCN8A) is a major voltage-gated sodium channel in the mammalian CNS, and i

105 trocytes in vitro have been shown to express voltage-gated sodium channels in a dynamic manner, with

106 Human studies have firmly implicated voltage-gated sodium channels in human pain disorders, a

107 Na(v)1.7 and other voltage-gated sodium channels in mouse DRG are considere

108 now linked multiple human pain disorders to voltage-gated sodium channels, including disorders chara

109 hree disulfide bridges, is a pore blocker of voltage-gated sodium channels, including neuronal subtyp

110 Voltage-gated sodium channels initiate action potentials

111 Voltage-gated sodium channels initiate action potentials

112 Voltage-gated sodium channels initiate electrical signal

113 The Nav1.1 voltage-gated sodium channel is a critical contributor t

114 The ion translocation process seen in this voltage-gated sodium channel is clearly different from t

115 The voltage-gated sodium channel is critical for cardiomyocy

116 The NaV1.7 voltage-gated sodium channel is implicated in human pain

117 congenital insensitivity to pain (CIP); this voltage-gated sodium channel is therefore a key target f

118 Ion permeation through voltage-gated sodium channels is modulated by various dr

119 Inhibition of voltage-gated sodium channels is neuroprotective in prec

120 gia, the first human pain syndrome linked to voltage-gated sodium channels, is widely regarded as a g

121 Nav1.6 is the primary voltage-gated sodium channel isoform expressed in mature

122 The voltage-gated sodium channel isoform Na(V)1.7 is highly

123 at, while VPA is capable of binding to these voltage-gated sodium channels, it has a very different m

124 1-type sodium channels and to substitute for voltage-gated sodium channels lacking in many invertebra

125 utations in Nav.1.7, the main pain signaling voltage-gated sodium channel, lead to its truncations an

126 ive axonal potentials that are maintained by voltage-gated sodium channels, leading to a declination

127 hether manipulation of splicing of mammalian voltage-gated sodium channels may be exploitable to prov

128 e results suggest that altered processing of voltage-gated sodium channels may contribute to aberrant

129 ular determinants of toxin interactions with voltage-gated sodium channels may permit development of

130 Axonal voltage-gated sodium channel mRNA and local trafficking

131 The finding of voltage-gated sodium channel mutations in small fibre ne

132 The sarcolemmal voltage gated sodium channel Na(V)1.4 conducts the key d

133 ant mutations in the SCN1A gene encoding the voltage-gated sodium channel Na(v) 1.1.

134 aploinsufficiency of the SCN1A gene encoding voltage-gated sodium channel Na(V)1.1 causes Dravet's sy

135 Mutations in SCN1A, encoding the voltage-gated sodium channel Na(V)1.1, are the most comm

136 sufficiency of the SCN1A gene encoding brain voltage-gated sodium channel Na(V)1.1.

137 Mutations in the gene encoding the cardiac voltage-gated sodium channel Na(v)1.5 cause various card

138 Voltage-gated sodium channel Na(v)1.5 generates cardiac

139 The function of the human voltage-gated sodium channel Na(V)1.5 is regulated in pa

140 tage-gated potassium channel K(V)1.3 and the voltage-gated sodium channel Na(V)1.7 as examples of tar

141 Gain-of-function missense mutations of voltage-gated sodium channel Na(V)1.7 have been linked t

142 Voltage-gated sodium channel Na(V)1.7 is a genetically v

143 The voltage-gated sodium channel Na(V)1.7 is believed to be

144 In humans, functional loss of the voltage-gated sodium channel Na(v)1.7 leads to pain inse

145 The voltage-gated sodium channel Na(v)1.7 plays a crucial ro

146 ansient receptor potential channel TRPA1 and voltage-gated sodium channel Na(v)1.7, that accompany al

147 FN for mutations in the SCN9A gene, encoding voltage-gated sodium channel Na(V)1.7, which is preferen

148 SCN9A encodes the voltage-gated sodium channel Na(v)1.7, which is present

149 The voltage-gated sodium channel Na(v)1.8 is known to functi

150 monstrates that two disease mutations in the voltage-gated sodium channel Na(v)1.8 that induce nocice

151 ination of a high-resolution 3D structure of voltage-gated sodium channel Na(V)Ab opens the way to el

152 ins, PIIIA, effectively blocks the bacterial voltage-gated sodium channel Na(V)Ab, whose crystal stru

153 Voltage-gated sodium channels Na(v)1.2 and Na(v)1.6 are

154 ch information learned in recent years about voltage gated sodium channel (Na(V)) subtypes in somatos

155 A biophysical analysis revealed voltage-gated sodium channel (Na(V)) currents in menthol

156 The cardiac voltage-gated sodium channel (Na(V)1.5) underlies impuls

157 Human nociceptive voltage-gated sodium channel (Na(v)1.7), a target of sig

158 n dissection, that the Silicibacter pomeroyi voltage-gated sodium channel (Na(V)Sp1) PD forms a stand

159 Peripheral sensory neurons express multiple voltage-gated sodium channels (Na(V) ) critical for the

160 trodotoxin (TTX), a neurotoxin that binds to voltage-gated sodium channels (Na(v) proteins), arrestin

161 Voltage-gated sodium channels (Na(V)) are indispensable

162 Voltage-gated sodium channels (Na(v)) underlie the rapid

163 alpha-toxins affect insect and/or mammalian voltage-gated sodium channels (Na(v)s) and thereby modif

164 The tremendous therapeutic potential of voltage-gated sodium channels (Na(v)s) has been the subj

165 Voltage-gated sodium channels (Na(v)s) initiate the acti

166 Voltage-gated sodium channels (Na(V)s) provide the initi

167 Voltage-gated sodium channels (Na(V)s) underlie the upst

168 nefarious effects result from inhibition of voltage-gated sodium channels (Na(V)s), the obligatory p

169 uit of novel subtype-selective modulators of voltage-gated sodium channels (Na(v)s).

170 s of sodium conductance across membranes are voltage-gated sodium channels (Na(V)s).

171 r the ion transport function mediated by the voltage-gated sodium channel, Na(V)1.2.

172 nce-conferring amino acid substitutions in a voltage-gated sodium channel, Na(v)1.4, are clustered in

173 Three voltage-gated sodium channels, Na(v)1.7, Na(v)1.8, and N

174 quantify isoflurane binding to the bacterial voltage-gated sodium channel NaChBac.

175 ABSTRACT: Voltage-gated sodium channel NaV 1.7 is required for acu

176 binds to the domain II voltage sensor in the voltage-gated sodium channel Nav and modifies its voltag

177 Voltage-gated sodium channel (NaV) mutations cause genet

178 Voltage-gated sodium channel (NaV) trafficking is incomp

179 metabotropic glutamate receptor-1 (mGluR1), voltage-gated sodium channels (Nav ) and glutamate trans

180 Ts3 binds to the domain IV voltage sensor of voltage-gated sodium channels (Nav ) and slows down thei

181 phibian prey, which select for TTX-resistant voltage-gated sodium channels (Nav) [12-16].

182 They are rich in voltage-gated sodium channels (Nav) and thus underpin ra

183 myelinated nerves requires the clustering of voltage-gated sodium channels (Nav) at nodes of Ranvier

184 heless, Nfasc140, like Nfasc186, can cluster voltage-gated sodium channels (Nav) at the developing no

185 We examined the repertoire of voltage-gated sodium channels (NaV) in fluorescence-sort

186 mans and other vertebrates, target conserved voltage-gated sodium channels (NaV) of nerve and muscle,

187 Voltage-gated sodium channels (NaV) play an important ro

188 and whether human SAN excitability requires voltage-gated sodium channels (Nav) remains controversia

189 ic tension, the thermal random motion of the voltage-gated sodium channels (Nav), which are bound to

190 Conotoxins act by inhibiting inactivation of voltage-gated sodium channels (Nav).

191 The beta1 subunit of voltage-gated sodium channels, Nav beta1, plays multiple

192 n the SCN1A gene, which encodes brain type-I voltage-gated sodium channel NaV1.1.

193 d by loss-of-function mutations in the brain voltage-gated sodium channel NaV1.1.

194 of an adjacent gene (SCN2A) coding for human voltage-gated sodium channel NaV1.2 (P = 9 x 10(-4)).

195 Mutations in SCN2A, a gene encoding the voltage-gated sodium channel Nav1.2, have been associate

196 Therefore, EC cells use Scn3a-encoded voltage-gated sodium channel NaV1.3 for electrical excit

197 ed a critical role for the regulation of the voltage-gated sodium channel NaV1.5 in the heart by the

198 We investigated the effect of LITAF on the voltage-gated sodium channel Nav1.5, which is critical f

199 SCN5A encodes the alpha-subunit of the voltage-gated sodium channel NaV1.5.

200 This is due to the voltage-gated sodium channel Nav1.7 (Scn9a), previously

201 ates that the expression and function of the voltage-gated sodium channel Nav1.7 are increased in a p

202 Mutations in the voltage-gated sodium channel Nav1.7 are linked to inheri

203 Human genetic studies have implicated the voltage-gated sodium channel NaV1.7 as a therapeutic tar

204 inflammatory pain requires the expression of voltage-gated sodium channel Nav1.7 but its significance

205 unction mutations in the SCN9A gene encoding voltage-gated sodium channel Nav1.7 cause congenital ins

206 Voltage-gated sodium channel Nav1.7 is a central player

207 Trafficking of the voltage-gated sodium channel NaV1.7 is dysregulated in n

208 The human voltage-gated sodium channel Nav1.7 plays a crucial role

209 Gain-of-function mutations of voltage-gated sodium channel Nav1.7 underlie dorsal root

210 Functional variants of voltage-gated sodium channel Nav1.7, encoded by SCN9A, h

211 iant in the second intracellular loop of the voltage-gated sodium channel NaV1.7, encoded by the SCN9

212 ndromes have been linked to mutations in the voltage-gated sodium channel Nav1.7.

213 Under physiological conditions, the voltage-gated sodium channel Nav1.8 is expressed almost

214 notoxins MrVIA, MrVIB, and MfVIA inhibit the voltage-gated sodium channel NaV1.8, a well described ta

215 ies have confirmed an important role for the voltage-gated sodium channel Nav1.9 in human pain disord

216 dromes, and variants of genes coding for the voltage-gated sodium channels Nav1.8 (SCN10A) and Nav1.9

217 nsfer (LRET) between the rat skeletal muscle voltage-gated sodium channel (Nav1.4) and fluorescently

218 des the alpha-subunit of the skeletal muscle voltage-gated sodium channel (Nav1.4).

219 Gain-of-function mutations in the voltage-gated sodium channel (Nav1.5) are associated wit

220 Cardiac voltage-gated sodium channels (Nav1.5) play an essential

221 ge-gated sodium channel (SCN5A gene encoding voltage-gated sodium channel [NaV1.5]) cause congenital

222 c evidence has clearly demonstrated that the voltage-gated sodium channel, Nav1.7, is critical to pai

223 multiple elements within the promoter of the voltage-gated sodium channel, Nav1.7, leading to a syner

224 The X-ray structure of the bacterial voltage-gated sodium channel NavAb has been reported in

225 enic mice, also cleaves the beta2-subunit of voltage-gated sodium channels (Navbeta2).

226 Voltage-gated sodium channels (NaVs) are activated by tr

227 Voltage-gated sodium channels (NaVs) are central element

228 Mutations in voltage-gated sodium channels (Navs) can cause alteratio

229 It is characterized by the dysregulation of voltage-gated sodium channels (Navs) expressed in dorsal

230 Voltage-gated sodium channels (Navs) play crucial roles

231 Voltage-gated sodium channels (Navs) play essential role

232 Improper function of voltage-gated sodium channels (NaVs), obligatory membran

233 in part due to changes in the properties of voltage-gated sodium channels (Navs).

234 ty resulting from point mutations within the voltage-gated sodium channel of the insect nervous syste

235 These results suggest that sanshool targets voltage-gated sodium channels on Adelta mechanosensory n

236 ptic drug carbamazepine was found to inhibit voltage-gated sodium channels only with external, but no

237 at paralog-conserved sites were enriched in voltage-gated sodium channels, particularly the alpha su

238 Voltage-gated sodium channels play a critical role in ce

239 KEY POINTS: Voltage-gated sodium channels play a fundamental role in

240 Whereas voltage-gated sodium channels play a well known and impo

241 ture of the open conformation of a bacterial voltage-gated sodium channel pore from Magnetococcus sp.

242 ut not blockers of AMPA/kainate receptors or voltage-gated sodium channels, prevented microglial outg

243 oltage dependence of the rat skeletal muscle voltage-gated sodium channel rNav1.4 expressed in oocyte

244 Mutations in the neuronal voltage-gated sodium channel SCN1A are associated with a

245 revealed that the didy mutation disrupts the voltage-gated sodium channel Scn1lab (Nav1.lb).

246 Mutations of the cardiac voltage-gated sodium channel (SCN5A gene encoding voltag

247 tiated and propagated by a single isoform of voltage gated sodium channels - SCN5A.

248 euritis at concentrations at which it blocks voltage-gated sodium channels selectively.

249 of organic cation selectivity of eukaryotic voltage-gated sodium channels showed a sharp size cut-of

250 perties were independent of modifications in voltage-gated sodium channels since 100 nM bifenthrin ha

251 ilayer affinity and in vitro activity at the voltage-gated sodium channel subtype 1.7 (Na(V)1.7), a c

252 Specifically, voltage-gated sodium channel subtype NaV 1.7 is required

253 tations in the human SCN1A gene encoding the voltage-gated sodium channel subunit Nav 1.1.

254 interneuron-specific and PV cell-predominant voltage-gated sodium channel subunit Nav1.1.

255 xpression of a human-specific isoform of the voltage-gated sodium channel subunit SCN4B was significa

256 CN10A, which encodes a nociceptor-associated voltage-gated sodium channel subunit, as a modulator of

257 ciated with the cleavage of Neuregulin and a voltage-gated sodium channel subunit.

258 the central nervous system (CNS) containing voltage-gated sodium channels targeted by deltamethrin.

259 Thus, structural properties of eukaryotic voltage-gated sodium channels that are suggested by func

260 ed and likely to have evolved from ancestral voltage-gated sodium channels that are widely expressed

261 that heterologously expressed human cardiac voltage-gated sodium channel, the principle cardiac sodi

262 knockdown, alter splicing of the Drosophila voltage-gated sodium channel to favour inclusion of exon

263 um2 is able to directly bind the predominant voltage-gated sodium channel transcript (NaV1.6) express

264 We determined the structure of a voltage-gated sodium channel, two-pore channel 3 (TPC3),

265 Voltage-gated sodium channels underlie the rapid regener

266 mutation in SCN11A, which encodes the Nav1.9 voltage-gated sodium channel, underlies a human disorder

267 osequencing genotyping and sequencing of the voltage gated sodium channel (VGSC) gene did not detect

268 Voltage-gated sodium channel (VGSC) activity has previou

269 Voltage-gated sodium channel (VGSC) beta subunits signal

270 Voltage-gated sodium channel (VGSC) beta1 subunits are m

271 plasticity, we used brevetoxin-2 (PbTx-2), a voltage-gated sodium channel (VGSC) gating modifier, to

272 Veratridine (VTD) is a voltage-gated sodium channel (VGSC) modifier that is use

273 Voltage-gated sodium channel (VGSC) mutations cause seve

274 ecent genetic studies have linked pathogenic voltage-gated sodium channel (VGSC) variants to human pa

275 mutations L1014F and L1014S within the para voltage-gated sodium channel (VGSC).

276 -14) bind to the C termini (CTs) of specific voltage-gated sodium channels (VGSC) and thereby regulat

277 Voltage-gated sodium channels (VGSC) are transmembrane p

278 We hypothesize that the voltage-gated sodium channels (VGSC) on the dorsal root

279 Notably, voltage-gated sodium channels (VGSC) that are crucial fo

280 agnitude shorter than the activation time of voltage-gated sodium channels (VGSC) would evoke action

281 s to efficiently overexpress large mammalian voltage-gated sodium channels (VGSC).

282 f structural and functional relationships of voltage-gated sodium channels (VGSC).

283 sed to contribute to anesthetic effects, the voltage gated sodium channels (VGSCs) should also be con

284 ies of myelinated fibres, however, show that voltage-gated sodium channels (VGSCs) aggregate with cel

285 KCNQ2/3 (Kv7.2/7.3) channels and voltage-gated sodium channels (VGSCs) are enriched in th

286 Voltage-gated sodium channels (VGSCs) are essential to t

287 Voltage-gated sodium channels (VGSCs) are important for

288 Voltage-gated sodium channels (VGSCs) are responsible fo

289 benzyl-3-methoxypropanamide (LCM)) modulates voltage-gated sodium channels (VGSCs) by preferentially

290 We have recently demonstrated that voltage-gated sodium channels (VGSCs) in dorsal root gan

291 nodes of Ranvier are sites of clustering of voltage-gated sodium channels (VGSCs) in nervous systems

292 Voltage-gated sodium channels (VGSCs) regulate invasion

293 Clustering of voltage-gated sodium channels (VGSCs) within the neurona

294 thrombin effect on neuronal excitability and voltage-gated sodium channels was assessed using extrace

295 Kidins220 association with brain voltage-gated sodium channels was shown by co-immunoprec

296 acts on various targets in vitro, including voltage-gated sodium channels, was initially proposed as

297 cing the primary pyrethroid target site, the voltage-gated sodium channel, we show that point mutatio

298 rt toxic effects by altering the function of voltage-gated sodium channels, which are essential for p

299 in mammals, nine genes encode nine distinct voltage-gated sodium channels with different amino acid

300 Blockade of voltage-gated sodium channels with TTX and reverse (Ca(2