ライフサイエンスコーパス: volvulus

1 h age (equivalent to years of exposure to O. volvulus).

2 als were largely misidentified as Onchocerca volvulus.

3 h Ags from the parasitic helminth Onchocerca volvulus.

4 apable of inducing protective immunity to O. volvulus.

5 acted from the parasitic helminth Onchocerca volvulus.

6 species Wuchereria bancrofti and Onchocerca volvulus.

7 s of multiple ivermectin doses on Onchocerca volvulus.

8 er blindness), which is caused by Onchocerca volvulus.

9 s warranted to prevent obstruction or midgut volvulus.

10 es to the human helminth pathogen Onchocerca volvulus.

11 nous CV and SV, and 18% for transverse colon volvulus.

12 he goal of elimination of transmission of O. volvulus.

13 smitter-derived secretion metabolite from O. volvulus.

14 ailure to do so leads to gut malrotation and volvulus.

15 site representing the closest relative of O. volvulus.

16 ceived a clinical diagnosis other than cecal volvulus.

17 d split wall have high specificity for cecal volvulus.

18 r as biomarkers of treatment efficacy for O. volvulus.

19 complications of DPEJ, including small bowel volvulus.

20 ing enterocolitis, gastroschisis, and midgut volvulus.

21 obstruction is significantly associated with volvulus.

22 nutrition dependent were more likely to have volvulus (1.2 vs 22.2%, P < 0.001), shorter percent resi

23 us (19 [59%] of 32) than in patients without volvulus (11 [16%] of 68) (P<.001).

24 ts was significantly higher in patients with volvulus (19 [59%] of 32) than in patients without volvu

25 n were transition points not associated with volvulus (31 [46%] of 68 patients) (P<.005).

26 ctions (Wuchereria bancrofti = 6, Onchocerca volvulus = 33, Loa loa = 150, Mansonella perstans = 130,

27 erase from the parasitic nematode Onchocerca volvulus, a major cause of blindness in Africa.

28 ted that rOv-ASP-1, a recombinant Onchocerca volvulus activation associated protein-1, was a potent a

29 ously, and a soluble antigen extract from O. volvulus adult worms (OvAg) was injected into the cornea

30 In O. volvulus adult worms the Ov-SPI proteins are localized t

31 n and intracorneal injection with soluble O. volvulus Ags (OvAg), and that the inflammatory response

32 and injected intrastromally with Onchocerca volvulus Ags.

33 L3 and a recombinant L3-specific protein, O. volvulus ALT-1) which were significantly increased or ma

34 d significantly with age, although not to O. volvulus ALT-1, which may have unique L3-specific epitop

35 l punch' to knockout human infection with O. volvulus altogether.

36 6-100 years) with surgically confirmed cecal volvulus and 12 control patients were reviewed.

37 Diagnoses of O volvulus and antibodies to HNPs were made using lucifera

38 yosin from the tropical parasites Onchocerca volvulus and Brugia malayi.

39 Both recombinant O. volvulus and C. elegans cyclophilins were found to posse

40 Baseline statistical values for the cecal volvulus and control groups were analyzed by using a two

41 onse, and concurrent helminth infections (O. volvulus and intestinal helminths) may alter TT-specific

42 Coexisting volvulus and ischemia were diagnosed with low sensitivit

43 Here, we describe the chromosomes of O. volvulus and its Wolbachia endosymbiont.

44 Onchocerca volvulus and lymphatic filariae, causing river blindness

45 of the expressed sequence tag datasets of O. volvulus and other filariae identified four other member

46 a patient with short-gut syndrome caused by volvulus and severe cholestatic liver disease who underw

47 ochengi is the closest extant relative of O. volvulus and shares several key natural history traits w

48 dding syndrome is strongly associated with O volvulus and the pathogenesis is probably mediated throu

49 matodes Acanthocheilonema viteae, Onchocerca volvulus, and Brugia malayi, strongly supporting the con

50 superior mesenteric artery syndrome, midgut volvulus, and diverticula are presented.

51 ne for diseases such as intestinal atresias, volvulus, and necrotizing enterocolitis.

52 rotizing enterocolitis, neutropenic colitis, volvulus, and sepsis.

53 Onchocerca volvulus antigen (OvAg)-stimulated peripheral blood mono

54 unoglobulin G4 to the recombinant Onchocerca volvulus antigen Ov-16 was modified to detect antibodies

55 ts IgG4 antibodies to recombinant Onchocerca volvulus antigen Ov16 with serum samples from patients w

56 The Onchocerca volvulus antigen Ov39 is cross-reactive with the retinal

57 cross-reactive antibodies to the Onchocerca volvulus antigen Ov39.

58 neal inflammation induced by Wolbachia or O. volvulus antigens containing Wolbachia is completely dep

59 olony-stimulating factor responses to all O. volvulus antigens unrelated to age.

60 and injected intrastromally with soluble O. volvulus antigens.

61 which Ags from the parasitic worm Onchocerca volvulus are injected into the corneal stroma.

62 Second, the bowel graft was prone to volvulus around the skeletonized donor portal vein.

63 ew the control and elimination of Onchocerca volvulus as a public health problem.

64 ed circulating nucleic acids from Onchocerca volvulus as an alternative to skin snips.

65 uld be guided by what is done for Onchocerca volvulus as there are no data for O. lupi.

66 a better understanding of the biology of O. volvulus as well as for the identification of novel targ

67 ae of the human filarial parasite Onchocerca volvulus, belongs to the family 18 glycosyl hydrolases a

68 To determine whether in utero exposure to O. volvulus biases a child's subsequent immune responses, c

69 O. volvulus blisterase expressed in insect cells has maxima

70 ssays with fluorescent peptides show that O. volvulus blisterase requires a P4 arginine and a basic a

71 s indicate that concurrent infection with O. volvulus can diminish the immune response to an unrelate

72 h the parasitic filarial nematode Onchocerca volvulus can lead to severe visual impairment and ultima

73 010 was retrospectively reviewed for colonic volvulus cases admitted emergently.

74 milar localization of the related Onchocerca volvulus cathepsin Z protein suggests that the function

75 We evaluated Onchocerca volvulus community microfilarial intensity and prevalenc

76 ivation, we injected a soluble extract of O. volvulus containing Wolbachia bacteria into the corneal

77 In addition, O. volvulus contains the rickettsial endosymbiont Wolbachia

78 mortality in cases of sigmoid (SV) and cecal volvulus (CV) taking into account preoperative and opera

79 gative for Mf: 16 (57%) were positive for O. volvulus DNA in the PCR-based assay.

80 s indicate that concurrent infection with O. volvulus does not prevent the development of a protectiv

81 loa, and microscopically misidentified as O. volvulus due to their superficially similar morphology.

82 hepsin L in the filarial nematode Onchocerca volvulus, eggshell and cuticle, suggests that some of th

83 rtant option for achieving and sustaining O. volvulus elimination.

84 or emergent procedures for malrotation with volvulus, esophageal foreign body, and ovarian and testi

85 s undergoing procedures for malrotation with volvulus, esophageal foreign body, ovarian torsion, or t

86 oreover, several of these highly distinct C. volvulus evolutionarily significant units (ESU) are like

87 ng an intrastromal injection of a soluble O. volvulus extract.

88 ve laurel wilt vectors in avocado, Xyleborus volvulus (Fabricius) and Xyleborus bispinatus (Eichhoff)

89 endosymbiotic Wolbachia in B. malayi and O. volvulus filaria are dependent on TLR2-TLR6 interactions

90 d were frequently complicated by small-bowel volvulus (five of 14) and bowel ischemia (six of 14).

91 Seven patients had volvulus; four had bowel ischemia.

92 ne protease in the development of Onchocerca volvulus fourth stage larvae (L4) by testing the effect

93 Other O. volvulus genes showed homology only to predicted genes f

94 We describe O. volvulus genome variation in 27 isolates from the early

95 ant DNA repeat families identified in the O. volvulus genome were also evaluated.

96 Thus, in utero exposure to O. volvulus has a long-term effect on the child's subsequen

97 sfully the complete life cycle of Onchocerca volvulus has hindered progress towards unravelling the p

98 CT demonstrated signs of volvulus in four of six patients with ischemia.

99 une response to the filarial worm Onchocerca volvulus in humans.

100 rotective immunity against larval Onchocerca volvulus in mice depends on the development of a Th2 imm

101 e immune response to the larval stages of O. volvulus in mice immunized with irradiated larvae.

102 or adaptive protective immunity to larval O. volvulus in mice.

103 Ts and neutrophils were visualised around O. volvulus in nodules excised from untreated patients but

104 lbachia bacterial endosymbiont of Onchocerca volvulus in these reactions, serum samples collected bef

105 t of a protective immune response against O. volvulus in TLR4-mutant mice is not due to loss of Th2 i

106 thogenesis is probably mediated through an O volvulus induced autoantibody response to multiple prote

107 inth that causes river blindness (Onchocerca volvulus) induces eosinophil recruitment to the corneal

108 ment of Onchocerca volvulus infection, 40 O. volvulus-infected Ghanaians were randomized to receive p

109 Stratification of the O. volvulus-infected group into two groups representing lig

110 cytokine, and antibody response to TT of O. volvulus-infected subjects (n = 19) and comparable nonin

111 unts were examined in 2 groups of Onchocerca volvulus-infected subjects after ivermectin treatment.

112 Onchocerca volvulus infection has been associated with impaired cel

113 general perception has been that Onchocerca volvulus infection is well on its way towards extinction

114 immune response, the effect of concurrent O. volvulus infection on the immune response to tetanus tox

115 may render the child more susceptible to O. volvulus infection postnatally.

116 humped pattern with host age, patterns of O. volvulus infection vary markedly with locality.

117 y and its potential mechanisms in Onchocerca volvulus infection were examined by analyzing cytokine a

118 vaccination in 193 subjects with Onchocerca volvulus infection with 85 comparable noninfected contro

119 reactions after the treatment of Onchocerca volvulus infection, 40 O. volvulus-infected Ghanaians we

120 th OV-16 improved serologic assessment of O. volvulus infection, a current unmet need toward the goal

121 bits high sensitivity and specificity for O. volvulus infection, and has great potential as a tool fo

122 an current methods for diagnosing Onchocerca volvulus infection, and it overcomes many difficulties i

123 are critical for establishment of Onchocerca volvulus infection, the third-stage larvae (L3) and the

124 jor cause of visual impairment in Onchocerca volvulus infection.

125 ve antitetanus response, although heavier O. volvulus infections are able to alter the magnitude of t

126 ith responses in 43 subjects with chronic O. volvulus infections.

127 und also to completely inhibit molting of O. volvulus infective L3 stage larvae.

128 ilation, band slippage, perforation, gastric volvulus, intraluminal band erosion, and port- and band-

129 Colonic volvulus is a rare cause of bowel obstruction in the Uni

130 Colonic volvulus is a rare entity associated with high mortality

131 Infection with Onchocerca volvulus is associated with the prevalence of severe vis

132 Targeting the Wolbachia in O. volvulus is effective in clearing microfilariae in the s

133 an individuals from an area where Onchocerca volvulus is hyperendemic have been monitored for infecti

134 The life expectancy of adult O. volvulus is reduced by approximately 50% and 70% after 3

135 When cecal volvulus is suspected, the absence of distal colonic dec

136 The filarial nematode Onchocerca volvulus is the causative organism of river blindness.

137 ria bancrofti) or onchocerciasis (Onchocerca volvulus) is doxycycline.

138 ate that CD4(+) T cells mediate sustained O. volvulus keratitis by regulating eosinophil recruitment

139 To examine the role of IFN-gamma in O. volvulus keratitis, C57BL/6 and IFN-gamma(-/-) mice were

140 rated that in the murine model of Onchocerca volvulus keratitis, neutrophils and eosinophils are recr

141 antibodies directed against a recombinant O. volvulus L3 cysteine protease that was cloned and expres

142 been found to be critical for molting in O. volvulus L3 larvae.

143 ophoric activity was capable of affecting O. volvulus L3 molting and that the presence of both activi

144 t of each of its biological activities on O. volvulus L3 molting was investigated.

145 solates were clustered in the O. fasciata-O. volvulus lineage and were well separated from other fila

146 a small number of patients infected with O. volvulus, M. perstans, or W. bancrofti showed positive i

147 Using a mouse model of Onchocerca volvulus-mediated keratitis (river blindness), the prese

148 Conversely, expression of ICAM-1 in O. volvulus-mediated keratitis was significantly reduced af

149 Our results demonstrate that NATOG tracks O. volvulus metabolism in both worms and humans, and thus c

150 achieving sustained clearance of Onchocerca volvulus MF from the skin (P = .024).

151 ment for achieving sustained clearance of O. volvulus MF from the skin (p=0.024).

152 examination for the detection of Onchocerca volvulus microfiladermia (2 of 218 samples positive by b

153 nd enumeration of (skin-dwelling) Onchocerca volvulus microfilariae (mf) using the skin snip techniqu

154 individual level, between infection with O. volvulus microfilariae and bilateral blindness was exami

155 ivermectin treatment in Ghana has reduced O. volvulus microfilarial intensity and prevalence, but sub

156 We have shown a direct relation between O volvulus microfilarial load and host mortality in a comp

157 roon found an association between Onchocerca volvulus microfilarial load in childhood and risk of dev

158 he edible operculated land snail Cyclophorus volvulus (Muller, 1774) is a good example since it shows

159 Midgut volvulus (n=11) was the most common cause in the PG foll

160 Volvulus (N=17) and ischemia (N=17) were the most freque

161 mall-bowel obstruction (n=68) or small-bowel volvulus (n=32) were retrospectively identified.

162 ng's disease, necrotising enterocolitis, and volvulus neonatorum in 23 (45.1%) each.

163 isorder, induced by antibodies to Onchocerca volvulus or its Wolbachia symbiont, cross-reacting with

164 r 15 highly repeated targets from Onchocerca volvulus (Ov) and 11 from Onchocerca ochengi.

165 munophenotyping approach to study Onchocerca volvulus (Ov) population diversity.

166 ructures and a protein present in Onchocerca volvulus (OV).

167 from the human parasitic nematode Onchocerca volvulus, Ov-SPI-1, was identified through the analysis

168 rganization recommends monitoring Onchocerca volvulus Ov16 serology in children aged <10 years for st

169 isolated from the human parasite Onchocerca volvulus (OvCYP-16).

170 uses of Brugia malayi (BMRV1) and Onchocerca volvulus (OVRV1) shows that these viruses are abundant i

171 itional significant independent predictor of volvulus (P<.05).

172 proved the specificity for cross-reactive O. volvulus patient sera (100% sensitivity and 100% specifi

173 duction in the percentage of adult female O. volvulus positive for Wolbachia) is 91%-94% on average,

174 ted for (1) Loa MFD in blood samples, (2) O. volvulus presence by SST, and (3) Immunoglobulin (Ig) G4

175 g of an existing drug with impact against O. volvulus provides promise in the hunt for new therapies

176 ely, a Glu(124) (C. elegans) or Asp(123) (O. volvulus) residue present in a critical position.

177 of filarial infections caused by Onchocerca volvulus, resulting in Onchocerciasis or river blindness

178 According to the results, C. volvulus s.l., as currently recognized, consists of thre

179 ts of three distinct species in Thailand: C. volvulus s.s., C. occultus sp. nov., and C. borealis sp.

180 ars (IQR 6-10); 232 (97%) participants had O volvulus-specific antibodies and 157 (65%) had autoantib

181 Onchocerca volvulus-specific antibodies were present in all patient

182 While the serum levels of O. volvulus-specific immunoglobulin G (IgG), IgG subclasses

183 cipants testing positive for antibodies to O volvulus-specific proteins and concentrations of Ov16 or

184 with L. loa, Mansonella perstans, Onchocerca volvulus, Strongyloides stercoralis, or Wuchereria bancr

185 e caused by the filarial nematode Onchocerca volvulus that affects more than 37 million people, mainl

186 e caused by the filarial nematode Onchocerca volvulus that can lead to blindness and chronic disabili

187 patterns of human infection with Onchocerca volvulus (the cause of river blindness) in different con

188 ltered the global distribution of Onchocerca volvulus, the agent of river blindness, and further popu

189 implicated in the development of Onchocerca volvulus, the causative agent of onchocerciasis.

190 antigen of the parasitic nematode Onchocerca volvulus, the causative agent of river blindness in huma

191 cludes filarial pathogens such as Onchocerca volvulus, the cause of human onchocerciasis, or river bl

192 Efforts to control Onchocerca volvulus, the etiologic agent of river blindness, have b

193 es against antigens prepared from Onchocerca volvulus third-stage larvae (L3), molting L3 (mL3), and

194 Mice immunized with irradiated Onchocerca volvulus third-stage larvae developed protective immunit

195 our population dynamics model of Onchocerca volvulus transmission.

196 zymes that are likely to be essential for O. volvulus viability.

197 essed the relations between infection with O volvulus, visual acuity, and host mortality with data ob

198 ere present, the specificity for small-bowel volvulus was 100%.

199 Colonic volvulus was found to be the cause in 63,749 cases (1.90

200 rly exposure to or infection with Onchocerca volvulus was investigated in an autochthonous focus caus

201 Xyleborus volvulus was not repelled by methyl salicylate (MeSA) or

202 All phylogenetic trees revealed that C. volvulus was polyphyletic and comprised of three clades

203 Importantly, the chitinase OvCHT1 from O. volvulus was recently discovered, however, its exact rol

204 14 cases of malrotation with obstruction or volvulus were described (4.9%), of which 2 "symptomatic

205 Taxonomic boundaries for C. volvulus were examined and clarified using a combined mo

206 Transition points associated with volvulus were less likely to be located more than 7 cm a

207 that infect the filarial nematode Onchocerca volvulus were previously found to have an essential role

208 s to adult and infective larval stages of O. volvulus which are age related are consistent with the a

209 h Ags from the parasitic helminth Onchocerca volvulus (which causes river blindness).

210 Extracts of Brugia malayi and Onchocerca volvulus, which contain Wolbachia, directly stimulated h

211 induced by the filarial nematode Onchocerca volvulus, which harbors endosymbiotic Wolbachia bacteria

212 m the filarial parasitic nematode Onchocerca volvulus, which is transmitted by the blackfly vector Si

213 TLR4-mutant mice were immunized against O. volvulus with irradiated third-stage larvae, and it was

214 ography (CT) in the diagnosis of small-bowel volvulus, with surgical findings as the reference standa

215 essed the effect of targeting the Onchocerca volvulus Wolbachia endosymbionts with doxycycline for th

216 he corneal stroma, and that TLR2 mediates O. volvulus/Wolbachia-induced neutrophil activation and dev

217 hypothesized that protective immunity to O. volvulus would not develop in C3H/HeJ mice which have a

218 With the genomes of L. loa, Onchocerca volvulus, Wuchereria bancrofti, and Brugia malayi availa

219 is being conducted in areas where Onchocerca volvulus, Wuchereria bancrofti, and L. loa are coendemic