ライフサイエンスコーパス: washout

1 ention was prolonged with (68)Ga-FAPI-4 (25% washout).

2 anterol 100/25 mug or placebo (7-day minimum washout).

3 2 weeks and placebo for 12 additional weeks (washout).

4 ences between WT and APP/PS1 mice after drug washout.

5 nd delayed Golgi reassembly after nocodazole washout.

6 ere counterbalanced, separated by a two-week washout.

7 yolk-free eggs per day, separated by a 4-wk washout.

8 down, and inhibition of TNF biogenesis after washout.

9 ss followed by sustained rebound sleep after washout.

10 eversible GABA-AT resynthesis following drug washout.

11 e IOP was obtained on 2 different days after washout.

12 , 1.9 at 1 min after injection) with a rapid washout.

13 ligand concentration and reversed upon drug washout.

14 nd a reduction of vesicle release even after washout.

15 .5 at 1 min after injection) and rapid brain washout.

16 ate and magnitude of the contrast uptake and washout.

17 arterial hypervascularity and portal venous washout.

18 residual receptor activation continued after washout.

19 and 20.9 +/- 3.0 mm Hg, respectively, after washout.

20 he need for hydrodynamic shear and selective washout.

21 oderate initial brain uptake and rapid brain washout.

22 to a randomized crossover design with a 4-wk washout.

23 oration of the normal walking pattern during washout.

24 maintained for 4 weeks, followed by a 1-week washout.

25 channel that would otherwise cause bacterial washout.

26 rin (control)/d for 8 wk separated by a 4-wk washout.

27 ligand but are recruited to IBs after ligand washout.

28 All subjects underwent a 1-month washout.

29 ls could be drug resensitized following drug washout.

30 placebo for 16 weeks, followed by an 8-week washout.

31 e improvements persisted even after a 2-week washout.

32 whereas all other tissue demonstrated rapid washout.

33 De novo infection can counter this washout.

34 and the urinary albumin excretion rate after washout.

35 Treatment periods were separated by a 14-day washout.

36 e oscillometry, and multiple breath nitrogen washout.

37 brain was high (~5 SUV) and followed by slow washout.

38 t baseline, after treatment, and during drug washout.

39 0.2 +/- 0.2 mmol/L; KD: 1.0 +/- 0.5 mmol/L; washout: 0.2 +/- 0.1 mmol/L; and HCLF: 0.3 +/- 0.2 mmol/

40 ergetic diets of 4 wk each separated by 4-wk washouts: 2 diets rich in SFAs (12.4-12.6% of calories)

41 s 39.79 +/- 70.85; P = .001), and AUC during washout (-49.36 +/- 47.42 vs 42.65 +/- 97.09; P = .001).

42 +/- 67.72 vs 89.44 +/- 145.32; P = .001) and washout (-5.64 +/- 130.71 vs 166.83 +/- 204.44; P = .002

43 extension enrolled 65 of the patients after washout; after 12 weeks, we did an interim analysis.

44 ed to mf abundance, suggesting that rainfall washout and air mass movement are important predictors o

45 ed to intervention or usual care followed by washout and crossover, with independent assignment of pa

46 t reactor failures (characterized by biomass washout and failure of ammonia removal) that were preced

47 cilitation were present even after sAPPalpha washout and inhibition of receptor trafficking or protei

48 Medication washout and MDIOP measurement were repeated at 12 and 24

49 s followed by SLT, 3-month delay followed by washout and SLT, or 6-month delay followed by washout an

50 ashout and SLT, or 6-month delay followed by washout and SLT.

51 mouth followed by 2 weeks of a no treatment washout and then 12 weeks of placebo; subjects in group

52 placebo followed by 2 weeks of no treatment washout and then 12 weeks of valACV 500 mg twice daily.

53 days treatment periods, separated by a 6-day washout, and 3 alcohol drinking paradigm (ADP) sessions.

54 PET scans indicated good brain entry, rapid washout, and a favorable metabolism pattern.

55 monstrated a favorable biodistribution, slow washout, and excellent performance with respect to the q

56 lication and receptor deactivation after ATP washout, and makes the receptor pore permeable to NMDG+,

57 reversed within tens of seconds after oxo-M washout, and not relieved by a strong depolarization, su

58 n, including the effects of drug taper, drug washout, and placebo administration on mood state.

59 inhalation for 2 weeks, followed by a 2 week washout, and then crossed over to the other arm.

60 r (ACV) for 7 days followed by 5 days of ACV washout, and then the viruses can remain dormant for ano

61 erenhancement, 0.85 (95% CI: 0.81, 0.88) for washout appearance, and 0.84 (95% CI: 0.80, 0.87) for ca

62 tis in patients undergoing arthroscopic knee washout are serious.

63 > 0.1 for change), indicating absence of a 'washout' artifact seen in larger mammals.

64 nce Index (LCI), measured by multiple breath washout, as a means to track disease progression in pres

65 ity were assessed using a cyclosporine (CsA) washout assay.

66 In nocodazole washout assays, FAs in arrestin-deficient cells were unr

67 tery-to-artery thromboembolism with impaired washout at border zones was a common mechanism in stroke

68 FEV1 improvement (absolute change from post-washout baseline at week 12: placebo-to-ivacaftor, 5.0 p

69 irst drug for 28 days followed by 28 days of washout before taking the second drug for 28 days.

70 were willing to undergo a 1-week medication washout before the study start, and could not have had i

71 iagnosed by WSI and TM with a minimum 30-day washout between methodologies.

72 sing a randomized crossover design with 2-wk washouts between phases.

73 diet sequence, feeding period, baseline and washout biomarker concentrations, age, acculturation, an

74 g) increased up to 24 h after injection, and washout by 96 h was not significant.

75 Medullary hyperosmolarity is protected from washout by countercurrent exchange and efficient removal

76 The median washout coefficient (K (2)) was significantly lower in m

77 pulse oscillometry, multiple breath nitrogen washout, CT (in selected participants), and questionnair

78 ng phase 3 slope analysis of multiple-breath washout data) and resistance at 5 Hz minus resistance at

79 perturbations that induce (99m)Tc-sestamibi washout, demonstrating proof-of-concept for an imaging a

80 We propose accelerating reservoir washout during ART by triggering sequential waves of pol

81 ver, poor pharmaceutical absorption and drug washout during normal voiding can limit sustained drug c

82 Upon centrinone washout, each cancer cell line returned to an intrinsic

83 edback was removed during either learning or washout, errors reappeared with performance immediately

84 TCF7L2, JMJD6, and c-Myc and following BETi washout exhibited rapid restoration of c-Myc and JMJD6.

85 Washout experiments confirmed the rapid dissolution of S

86 Washout experiments demonstrated a lack of complete clea

87 we used microfluidics-assisted fast tubulin washout experiments to induce microtubule depolymerizati

88 ising time-dependent affinity determination, washout experiments, and [(35)S]GTPgammaS binding assays

89 The change in IOP following washout for patients using 0 (n = 100), 1 (n = 705), 2 (

90 y in patients who received arthroscopic knee washout for septic arthritis in England between April 1,

91 eek treatment periods, separated by a 4-week washout) for 52 weeks.

92 E], peak signal enhancement ratio [SER], and washout fraction) and normal tissue features (background

93 ak SUV of 3-5, followed by a uniformly quick washout from all brain regions in HE subjects; slower cl

94 uptake around 5 min after injection and fast washout from nontarget regions.

95 vity, the elimination slope of radioactivity washout from the brain (k (E,brain)) was calculated.

96 vity, the elimination slope of radioactivity washout from the brain (kE,brain) was calculated.

97 Furthermore, (11)C-metoclopramide washout from the brain was estimated by determining the

98 ble kinetic properties, with relatively fast washout from the brain.

99 r and the elimination slope of radioactivity washout from the lungs (k (E,lung)) was 70% lower in Abc

100 n the striatum expressing hP2X7R, with rapid washout from the noninjected control striatum and other

101 ths after the treatment (patients had 4-week washout from their glaucoma medication before their aque

102 penetration, low tumor specificity and rapid washout from tumors.

103 ciated with greater IOP rise upon medication washout: greater number of glaucoma medications, higher

104 All interventions induced (99m)Tc-sestamibi washout; hypoxia from 24.9 +/- 2.6% ID to 0.4 +/- 6.2%,

105 or protein low in BCAAs for 4 wk with a 2-wk washout in between.

106 uncoupled itself from the DNA following ETO washout, in an error-free manner.

107 for Golgi ribbon formation after nocodazole washout; in vitro, Mena and microfilaments enhanced GRAS

108 Key eligibility included washout IOP of 23 mmHg or more at time 0, IOP of 20 mmHg

109 The post-washout IOP was 16.2 +/- 2.2 mmHg.

110 cloud scavenging (as opposed to below-cloud "washout") is the main contributor to rain WSON.

111 ting yielded significantly faster uptake and washout kinetics than suboptimal heating in all organs f

112 ting yielded significantly faster uptake and washout kinetics than suboptimal heating in all organs f

113 Notably, single-dose treatment followed by washout leads to a prolonged reduction of tau levels and

114 Pre-pump obstruction was treated by washout maneuver in 9 cases (success rate, 100%), thromb

115 mpulse oscillometry (IOS) or multiple-breath washout (MBW) are associated with key asthmatic patient-

116 nically acceptable trials of multiple breath washout (MBW).

117 ts (80%) were able to undergo post-treatment washout measurements, and in these eyes, only 26.6% of e

118 g, exhaled nitric oxide, and multiple breath washout measures.

119 e imaging scan that was preceded by a 30-day washout (modified intent-to-treat population).

120 nd by using free-breathing dynamic (19)F gas washout MR imaging after inhalation of the gas mixture w

121 lung ventilation by using dynamic (19)F gas washout MR imaging in free breathing is feasible at 1.5

122 uine physical limit imposed by flow-mediated washout of active coagulation factors.

123 After a washout of all pre-study ocular hypotensive medications,

124 After a washout of all prestudy ocular hypotensive medications,

125 Washout of auxin and restoration of endogenous Plk4 leve

126 efforts, the whole world would experience a washout of benefit, amounting to almost 126.68-616.12 tr

127 Washout of Ceapins resensitized ATF6alpha to ER stress.

128 The consequential washout of CO(2), if cerebrovascular reactivity is impai

129 ibition was long lasting and not reversed on washout of DAMGO or by application of the mu-opioid rece

130 ase, resulted in first-order, time-dependent washout of deuterium from 6a.

131 on, whereas MRP3 was the key determinant for washout of gadoxetic acid at HBP (P < .001).

132 ble logistic regression analysis showed that washout of greater than 60 seconds was the contrast-enha

133 This effect was reversed following washout of HS38 and correlated with a reduction in the r

134 henotype upon regeneration despite confirmed washout of ionophores from tissue.

135 h established POAG were randomized to prompt washout of IOP-lowering medications followed by SLT, 3-m

136 re most predictive of HCC diagnosis, whereas washout of less than 60 seconds was the feature most pre

137 d triglyceride levels below 4.5 mmol/L after washout of lipid-lowering treatments.

138 ng applications and eliminating the need for washout of mislocalized sensor.

139 f those without FA treatment, suggesting the washout of NOB.

140 US contrast agents is valuable as the rapid washout of nonhepatocyte malignancies is highly contribu

141 Annual washout of ocular hypotensive medication was performed.

142 After a 1- to 3-week washout of phosphate binders, we randomly assigned 162 e

143 in gene silencing that can be reversed upon washout of the chemical dimerizer.

144 enefit of BPN14770 persisted two weeks after washout of the drug.

145 atory response was not affected by extensive washout of the drug.

146 In fact, washout of these chronically exposed cells for up to 1 m

147 The system described here achieved washouts of 1.5, 3.2, and 4.9 ms for NIST 612 glass, at

148 ng/ml concentrations of human Tg from needle washouts of fine-needle aspiration biopsies of thyroid n

149 the label-free detection of Tg in the needle washouts of fine-needle aspiration biopsies, at concentr

150 e tumor had classic arterial enhancement and washout on venous and delayed-phase computed tomography

151 At baseline following washout, open-angle glaucoma patients (n = 75) were admi

152 an adult; These effects were reversible upon washout or the addition of GLI or HMR1098.

153 anotransducer channels, recover upon blocker washout or tip link regeneration and can be replicated b

154 which demonstrated soluble contrast material washout over time.

155 parameters transfer constant (K (trans)) and washout parameter (k (ep)) derived from DCE MRI were com

156 The multiple-breath inert gas washout parameter acinar ventilation heterogeneity (Saci

157 with median and interquartile range of (19)F washout parameters.

158 After a 6-day washout, participants were crossed over to the treatment

159 After a 2-week washout, patients crossed over to the alternate therapy

160 In phase B, after a 2-week washout, patients were randomized to ezetimibe or evoloc

161 Following a minimum 7-day washout period (until the symptoms induced by the previo

162 itching to the other TNF inhibitor without a washout period after insufficient primary response to th

163 witching to a second TNF inhibitor without a washout period after primary failure to a first TNF inhi

164 ons were noted to persist following a 3-week washout period and corresponding restoration of circadia

165 ntly activated Notch followed by a prolonged washout period and observed that, in addition to decreas

166 the first intervention, followed by a 3 day washout period and then 5 days with the other interventi

167 or placebo for 4 weeks followed by a 2-week washout period and then crossover to the alternate treat

168 therapy for 4 weeks, followed by a 2-4 week washout period and then the other intervention for 4 wee

169 eek oral lead-in phase, followed by a 1 week washout period and, after safety assessment, three intra

170 n either an AB or BA sequence with a 10-week washout period at crossover.

171 Animals had a 7-day washout period before measures of hormone concentration

172 The mean washout period before the initiation of fingolimod was 2

173 twice weekly, each for 4 weeks with a 1 week washout period between crossover.

174 zed order for a minimum of 3 wk, with a 1-wk washout period between diets.

175 administered in a random order with a 28-day washout period between infusions.

176 orally in a crossover fashion after a 2-week washout period between treatments.

177 tween January 2004 and December 2014, with a washout period consisting of the 9 months before and aft

178 ed for a 10-week period followed by a 2-week washout period during which patients were bathed with no

179 as enhanced in LPS-trained MSCs, 3 d after a washout period following primary stimulation.

180 ervention phases were separated by a 6-month washout period for the installation of the system and fo

181 renia (N = 10) and after at least a two-week washout period from standard of care antipsychotics.

182 or men and women, respectively), with a 4-wk washout period in between the diets during which the sub

183 steroid for 1 to 2 weeks with a 1- to 2-week washout period in between.

184 00 mg BID for 14 days, or vice-versa, with a washout period in between.

185 randomized Latin square design study with a washout period of >/=14 d was conducted.

186 After the washout period of >/=28 d, the same participants consume

187 s who each completed 5 visits with a minimum washout period of 1 wk between testing days.

188 ional treatment for 26 weeks, separated by a washout period of 17 weeks.

189 vely] for 6 wk in a crossover design, with a washout period of 4 wk.

190 This injection was followed by a washout period of at least 3 days.

191 Medication conditions were separated by a washout period that was 7 days.

192 After a 4-mo washout period the participants switched diet.

193 the effect, followed by a randomised 4-week washout period to assess withdrawal effects.

194 Changes persisted during a 2 week washout period without weights.

195 y placebo for 8 weeks, followed by a 2-week "washout period" and then 8 weeks of the alternative trea

196 Following a washout period, 99 eligible subjects were randomly assig

197 LA and 0% GLA] for 4 wk, followed by an 8-wk washout period, before consuming the opposite oil for 4

198 After a 5-day washout period, five patients received 5 mg apixaban twi

199 or CD-TREAT for 7 days, followed by a 14-day washout period, followed by the alternate diet.

200 After a 1-week washout period, patients crossed over to treatment B (pl

201 After a 2-week washout period, subjects received the alternate treatmen

202 sed nightly for 4 wk (T2) followed by a 1-wk washout period, then 4 wk (T4) using the alternate OA.

203 0 E% fat) for 4 mo each, separated by a 2-wk washout period.

204 ebo or PF-04958242 for 5 days separated by a washout period.

205 intervention periods separated by an 8-week washout period.

206 daily) in random order separated by a 2 week washout period.

207 ion, which was separated from the first by a washout period.

208 ir regular medication, followed by a 12-week washout period.

209 from rice and seafood following a three-day washout period.

210 as followed by a 6-week single-blind placebo washout period.

211 ne if changes were sustained during a 4-week washout period.

212 he 2 assessments were separated by a 6-month washout period.

213 ly consumed for 2 wk and separated by a 4-wk washout period.

214 that were separated by a 14-d habitual diet washout period.

215 switched to the other TNF inhibitor with no washout period.

216 r US diet for 24 d each, separated by a 28-d washout period.

217 rage (CB) for 8 wk each, separated by a 4-wk washout period.

218 ) twice daily for 6 months after a screening washout period.

219 ven sequentially for 50 d followed by a 50-d washout period.

220 e daily or placebo for 6 weeks with a 2-week washout period.

221 irectly observed therapy period and a 4-week washout period.

222 onometry before and after a protocol-defined washout period.

223 d with iohexol, after 3 years plus a 2-month washout period.

224 gle-site, randomized crossover trial with no washout period.

225 elation treatment was permitted with a 7-day washout period.

226 ries from total fat) for 28 d with a >/=2-wk washout period.Consumption of the cashew diet resulted i

227 od [IP]) or sequence 1-0 (6-month IP/3-month washout period/6-month CP).

228 nce 0-1 (6-month control period [CP]/3-month washout period/6-month intervention period [IP]) or sequ

229 terbalanced conditions separated by a 2-week washout period: (1) daytime (intake limited to 0800 h-19

230 golimod treatment may happen even with short washout periods (4 weeks) and may perpetuate despite ste

231 one of four different sequences with 2-week washout periods between medications.

232 rage, 9.2, 22.5, 46.3 and 91 mg . d(-1) with washout periods of 2 wk between each intake.

233 carefully selecting treatment durations and washout periods to assess incremental improvement in air

234 n pelvis motion and step width, separated by washout periods to detect the presence of potential afte

235 d) or control in Trial 2 (n = 25), with 4-wk washout periods.

236 -DASH diet) for 3 wk each, separated by 2-wk washout periods.

237 Challenges were separated by 28-day washout periods.

238 This phenotype was fully reversed during the washout phase and readily reproducible across institutio

239 pression were all reversed by the end of the washout phase, indicating that the metabolic alterations

240 performed on the last day of treatment, and washout-phase measurements occurred more than 27 d after

241 yocardial activity/blood pool integral), and washout rate were calculated.

242 l the cardiac autonomic measures (except the washout rate) was associated with reduced CFR.

243 f [(18)F]DOPA influx rate to [(18)F]dopamine washout rate, an index of presynaptic dopaminergic funct

244 ed signal intensity, T2 value, wash-in rate, washout rate, time to peak (TTP), mean apparent diffusio

245 d as the late heart-to-mediastinum ratio and washout rate.

246 assessed with heart-to-mediastinal ratio and washout rates was preserved in all patients at baseline

247 gate, which explains their exceptionally low washout rates.

248 ceptional selectivity and very slow compound washout rates.

249 h calculation of enhancement ratio (ER), and washout ratio (WR).

250 Following puromycin washout, relocalization of ATI mRNA at inclusions depend

251 were tested; all showed similar activity and washout resistance.

252 tistically with gadoxetic acid retention and washout, respectively, in the HBP.

253 esponses to KCl and carbachol treatments and washouts, respectively.

254 e-related increase in myopia during phase 2 (washout), resulting in atropine 0.01% being most effecti

255 he LTP facilitation, persist after sAPPalpha washout, revealing a metaplastic capability of exogenous

256 up 2 and comparable multiple breath nitrogen washout S(acin) to control participants.

257 rformed to assess the gadobenate dimeglumine washout since the last gadolinium exposure.

258 = .002) and significantly reduced late-phase washout slope (P = .002) when compared with healthy cont

259 e first-pass peak (P = .011), and late-phase washout slope (P = .032), estimated by using the median

260 cant amount of drug (0.25%) leached into the washout solutions within 24 hours.

261 Following washout, subjects exhibited a strong and persistent afte

262 After a chloroquine washout, subjects, including treatment-naive infectivity

263 After chloroquine washout, subjects, including treatment-naive infectivity

264 s fast and uniform before whole-cell pipette washout, suggesting little voltage attenuation along the

265 died in vivo by use of the radioactive xenon washout technique after a hydrocortisone infusion (2 mg/

266 istribution derived from the multiple-breath washout technique.

267 CI determined by age-adapted multiple breath washout techniques and MRI studies were performed in 97

268 of HCC nodules classified as LR-3, and wide washout temporal range for LR-M observations are limitat

269 the slope of phase III of the single-breath washout test (S) of He (S(He)) and sulfur hexafluoride (

270 Multiple breath washout tests were performed at baseline, 1, 3, 6, and 1

271 tcome determined by multiple breath nitrogen washout that reflects ventilation heterogeneity in the m

272 After washout, the between-group difference in the mean iohexo

273 Upon inhibitor washout, the receptor is readily rephosphorylated.

274 After 4 weeks washout, the work protocol was repeated, and blood and b

275 eks; this treatment was followed by a 2-week washout, then the other study treatment was administered

276 llular TRE, we observed that, upon inhibitor washout, there was a rapid and dramatic regeneration of

277 Both uptake and washout time constants were faster (P < 0.01) in animals

278 curves were analyzed to calculate uptake and washout time constants.

279 ation rate (hyperemic index); SvO(2) yielded washout time of oxygen-depleted blood, rate of resaturat

280 sex, disability status, time on natalizumab, washout time, follow-up time, and study center).

281 ied by using volume defect percentage (VDP), washout time, number of breaths, and fractional ventilat

282 of breaths (r = -0.82; P < .0001) and median washout times (r = -0.77; P < .0001) with percentage pre

283 le undoubtedly a valuable research tool, the washout times and sensitivity of current technology have

284 found for the fluoroalkylamines such as fast washout times from the ESIMS system (ca. 30 min) and a 3

285 0 mg/dl and a 1.5-mg/dl increase from before washout) to one of six tenapanor regimens (3 or 30 mg on

286 ed four-way repeated-measures crossover with washout, to five boys (8-15 years) with ADHD.

287 ablation crater profiles [ACP]) and aerosol washout/transfer/ICPMS measurement (via single pulse res

288 P was measured in untreated subjects after a washout (up to 4 weeks) and eligibility phase.

289 Washout urine TFV concentrations and time to undetectabl

290 exhibit similar levels of IOP elevation upon washout, using standardized methodology to estimate real

291 he mean urinary albumin excretion rate after washout was 40% (95% CI, 0 to 80) higher with allopurino

292 ion, was slightly voltage-dependent, and its washout was accelerated by bovine serum albumin.

293 Control experiments confirmed that this washout was due to KR(0)-catalyzed isotope exchange of t

294 phosphate concentrations at baseline (after washout) were 7.32-7.92 mg/dl for tenapanor groups and 7

295 During washout when patients used conventional therapy, 7 patie

296 The treatments were separated by a 3-wk washout with AA-MFs.

297 y plethysmography, multiple-breath inert gas washout (with the tracer gas sulfur hexafluoride), and h

298 ight in-laboratory polysomnographies (1-week washout), with an epiglottic catheter, intramuscular gen

299 n of the recovery of fluorescence on agonist washout, with channel activation to a second agonist app

300 dies should carefully consider the length of washout within crossover designs.