ライフサイエンスコーパス: weak acid

1 4) occurred as a byproduct of treatment with weak acid.

2 o induce the second proton addition from the weak acid.

3 of the Mn catalyst with phenol as the added weak acid.

4 rence for the protonated acidic form of this weak acid.

5 al strong ions, and albumin is the principal weak acid.

6 of prions by sodium dodecyl sulfate (SDS) in weak acid.

7 e dinitrogen is observed upon treatment with weak acids.

8 ange, proton transfer was "rescued" by added weak acids.

9 xclusion chromatographic (ICE) separation of weak acids.

10 tion enhances the detectability of traces of weak acids.

11 s KCl and membrane-permeable solutes such as weak acids.

12 vely involved in the generation of H(2) from weak acids.

13 apable of yielding the terminal hydride from weak acids.

14 f carbon dioxide, strong ion difference, and weak acids.

15 lity in response to sodium lactate and other weak acids (1-20 mM) were studied.

16 Complex 1 also reacts with weak acids A-H (A-H = phenylacetylene, 1,2-propadiene, p

17 carried out and the need to protonate a very weak acid, a dithiolane sulfur atom in the former, and a

18 the cytosol was alkalinized by removing the weak acid acetate.

19 fusion system was used to apply solutions of weak acid (acetic acid, CO(2)) or base (ammonia) to loca

20 the results indicate that acids, especially weak acids, acidify the taste bud and evoke depolarizati

21 The exogenous low MW weak acids act as a replacement general base in the hydr

22 We now report that purified human Hyal2 is a weak acid-active hyaluronidase.

23 Hyaluronidase (HYAL)-2 is a weak, acid-active, hyaluronan-degrading enzyme broadly e

24 species with stoichiometric quantities of a weak acid afforded H2 and the monoanionic cobalt-diaryld

25 The distribution pattern of weak acid and amine nitroxide spin probes across the cel

26 conversion into amidines by treatment with a weak acid and an external amine.

27 ) mechanism, based on the variable charge of weak acid and base groups, which may invert the protein

28 5'-MHC is an amphipathic weak acid and is distinctly different from the cationic

29 ), and F(-), also including Zn(2+)) by using weak acid and weak base ion-exchange resins in the prese

30 utral nonpolar and polar compounds and seven weak acids and bases (pKa = 3-5.2) selected from among i

31 n earlier observations whereby cell-permeant weak acids and bases can modulate fluid secretion in epi

32 odel able to describe the retention times of weak acids and bases in all possible combinations of org

33 ysis at the electrodes, buffering effects of weak acids and bases, and mass transport due to both dif

34 ly 7.4 of all test compounds, especially the weak acids and bases, by up to 100-fold.

35 1(NH)](+) is strongly affected by relatively weak acids and proceeds at 5000 s(-1) with an overpotent

36 d on a binary mixture of particles coated by weak acids and weak bases under externally controlled os

37 6-trisulphonic acid (HPTS) and changed using weak acids and weak bases.

38 l ionogenic organic compounds (IOCs) such as weak acids and weak bases.

39 ical properties of good water solubility (in weak acid) and stability at ambient temperature and degr

40 Furthermore, catalysis is possible using a weak acid, and the complex is stable for at least 4 h in

41 olytic conditions were modeled using HCCR as weak acids, and trans-{kappaC,N-(3,4,5-(F)3-C6H2)CH2N ho

42 ve potentials, was isolated through use of a weak acid (anilinium, pKa = 10.6 in CH3CN) to avert prot

43 competition experiments and the finding that weak acid anion adsorption increased with surface carbox

44 FNTs facilitate weak acid anion/H(+) cotransport, whereas AQP water chan

45 porter, which catalyses the active efflux of weak acid anions from the cytosol of adapted cells.

46 ive detection of both common anions and very weak acid anions is described.

47 The weak acids are converted to potassium salts that are ful

48 ods for the determination of pK(a) values of weak acids are described, a direct titration with dimsyl

49 The determinations of several strong and weak acids are presented along with factors that govern

50 rated not only from water but also from such weak acids as dimethyl sulfoxide and acetonitrile.

51 ll three types of films, consistent with the weak acid-base behavior expected of polymers assembled i

52 nging the fractional exposure of the cell to weak acid/base altered the gradient, as did changing the

53 s did changing the concentration and type of weak acid/base applied.

54 this case, we observed increased activity if weak acid/base or neutral probes were used, while exposu

55 Acute displacement of pH(i) (superfusion of weak acids/bases) triggered rapid pH(i) recovery.

56 an in vitro human skin permeation study of a weak acid (benzoic acid) and a weak base (propranolol) a

57 e with the strength of the proton source for weak acids, but these apparent proton transfer rate cons

58 ring acidosis produced by application of the weak acid butyrate (30 mM).

59 Intracellular acidification, produced by the weak acid butyrate, application of CO2 at constant pHo o

60 c half of the protein; we suggest that these weak acids can affect proton transfers in the extracellu

61 lows the rapid quantitation of strong acids; weak acids can also be determined depending on pKa and i

62 s previously been shown that azide and other weak acids can influence proton transfers in the cytopla

63 Here, we demonstrate that BT2, a lipophilic weak acid, can act as a mitochondrial uncoupler.

64 cross the lipid bilayer when the hydrophobic weak acids, carbonylcyanide m-chlorophenylhydrazone and

65 The acid was used to regenerate weak acid cation (WAC) ion-exchange media used for water

66 EXS combines a weak acid cation exchange resin (WAC) to concentrate amm

67 Conversely, weak acids cause wild-type yeast to present nhx1Delta tr

68 suggest that an interfacial pK shift of the weak acid caused by the local electric field of photofor

69 be exploited for the treatment of cancer by weak acid chemotherapeutics.

70 rallel increase in tumor growth delay by the weak acid chlorambucil (CHL).

71 Protonation of 2 or 3 with various weak acids cleanly forms the parent arsinidene [(PN)(2)T

72 Transepithelial gradients of an alternative weak acid (CO2) produce pHo changes similar to SCFA.

73 lative electrolyte concentrations, and total weak acid concentrations.

74 acetic acid, was effective at 1.0 mm; and a weak acid control, benzoic acid, was ineffective.

75 gly acidic (pH </= 2) that suppresses eluite weak acid dissociation.

76 became possible after it was discovered that weak acids dramatically increase the rate of both the in

77 Similar concentration gradients for weak acid (e.g., CO(2)) occur across border zones during

78 fusion of acetate (salt of membrane-permeant weak acid), evoked a [Ca(2+)]i rise, independent of sarc

79 The addition of weak acids facilitates this reaction, whereas the additi

80 acid favors retention of configuration and a weak acid favors inversion of configuration.

81 oods, as it allows growth in the presence of weak acid food preservatives.

82 ith the conjugate bases of metal oxide based weak acids, generating multicompositional microboxes (Fe

83 atment of the putative iron(-I) complex with weak acids gives low yields of ammonia and hydrazine, de

84 react in various manners, including engaging weak acids (HA) in the reaction medium.

85 While weak acids have been shown to yield some pH sensitivity

86 Irrespective of lipophilicity, these ozonide weak acids have relatively low aqueous solubilities and

87 ive was capable of proton reduction from the weak acid [HPMe(2)Ph]BF(4) (pK(CD(2))(Cl(2)) = 5.7).

88 2H + HX --> NR2H2(+) + X(-)) and allows very weak acids HX (pKa >/= 7.0) that cannot normally be dete

89 ierarchical model provides support for using weak acid hydrolysis in the production of cellulose nano

90 g electrolyte (i.e., potassium iodide) and a weak acid (i.e., arsenious acid) as a function of the pH

91 rganic acids are composed of both strong and weak acids (i.e., pKa1 = 2.54, pKa2 = 6.19, and pKa3 = 7

92 The hydride complex (1) functions as a weak acid in D2O and partially dissociates into a rhodiu

93 ion potential but requires the presence of a weak acid in the solution for catalytic activity.

94 phy system to perform sensitive detection of weak acids in a second dimension.

95 mally metal(0) species before protonation by weak acids in acetonitrile.

96 ionizable organic chemicals (IOCs) that are weak acids in aqueous solution by fish can differ as a f

97 s H(+) reduction activity in the presence of weak acids in MeCN and evolves H2 upon protonation sugge

98 and exploitable determinant of the uptake of weak acids in the complex tumor microenvironment.

99 constraints associated with the reduction of weak acids in their ground state, thus offering a new pa

100 We find that the permeability of weak acids increases in the order of benzoic > acetic >

101 ive channel below pH 4.5, were absent before weak acid-induced heat activation of the mutant at pH 7.

102 monium acetate as a representative salt of a weak acid instead of saline for generator elution.

103 ication by CaCO3 is that starch may act as a weak acid ion exchanger capable of exchanging alcoholic

104 Interference from common weak acids is avoided by operating near pH 4.

105 ene, in the presence of lithium halide and a weak acid, is converted to 1-halotetrahydronaphthalene.

106 der palladium catalysis in the presence of a weak acid, isomerization to a 1-arylsulfonyl 1,3-diene o

107 As pABA is a hydrophobic weak acid, its uncharged form is membrane-permeant, and

108 dride complex ([(TSPP)Rh-D(D(2)O)](-4)) is a weak acid (K(a)(298 K) = (8.0 +/- 0.5) x 10(-8)).

109 The effects of the sodium salt of the weak acid lactate on tension and intracellular pH (pH1)

110 The weak-acid layer suppressed the competing hydrogen evolut

111 asured and controlled within an ~50-nm-thick weak-acid layer.

112 Subsequent addition of a weak acid liberates oxamide, which demonstrates that an

113 ice of water ICE was shown feasible for very weak acids like silicate and borate with a dedicated ele

114 e resulting phenolate to rebind protons from weak acids like water leads to rapid catalyst degradatio

115 It reacts with the weak acid lutidinium iodide to afford the eta(1)-allylic

116 er suggested mechanisms: (i) azide and other weak acids may function as proton carriers in the proton

117 salts (alkali metal salts of chloride) and a weak acid of common concern in water desalination (boric

118 orption and competitive interactions of five weak acids on a graphite surface was assessed in alkalin

119 investigation of the reduction of moderately weak acids on platinum reveals that they are reduced in

120 rter is not activated by oxidative, osmotic, weak acid or pH stress.

121 r mechanism but in a more effective way than weak acid or weak base and boosts mass spectrometry resp

122 The buffers in use contain a weak acid or weak base buffered by a compound with a dis

123 ackish water, and wastewater are amphoteric, weak acids or weak bases, and, thus, their properties de

124 proceed in a cooperative (strong anion then weak acid) or stepwise manner (weak acid then strong ani

125 actions and diffusion for solvent transport, weak acid permeation, and enzymatic reactions adjacent t

126 The addition of a large concentration of a weak acid-phenol-helps by cleaving one of the C-O bonds

127 gue, the [t-H2](+/0) couple is unaffected by weak acids (pK(a)(MeCN) = 15.3) but exhibits catalysis w

128 ed mechanism involves proton transfer from a weak acid (pKa = 7, where Ka is the acid constant) conce

129 Since free cyanide is a weak acid (pKa = 9.3), available protons compete for cya

130 notypes, yet it also confers a potential for weak acid preservative catabolism that the native S. cer

131 se is electrogenerated by the reduction of a weak acid (producing hydrogen) at a "submarine" ultramic

132 Herein, we have presented a weak acid-promoted tandem aza-Michael-aldol strategy for

133 The weak acid properties of papaverine hydrochloride were in

134 s, which makes the newly studied strong base-weak acid reaction essentially different from previously

135 Similar studies on strong (photo)base-weak acid reactions would also be of interest because ea

136 acellular concentration gradient of permeant weak acid readily induces pH(i) nonuniformity.

137 These weak acid-related chemicals are widely used as antifunga

138 nd bioavailability of emerging and classical weak acids released into natural waters.

139 activation might suppress the Mnl1-dependent weak acid response in dying cells.

140 Furthermore, the weak acid salicylate, which causes cytoplasmic acidifica

141 , an inducer of the soxRS system, and to the weak acid salt sodium salicylate (NaSal), an inducer of

142 cted differences in F15 oxidant, alcohol and weak acid sensitivities.

143 ping agent, we demonstrate that a variety of weak acids (silicate, borate, arsenite, cyanide, carbona

144 layed the withdrawal of a frog's foot from a weak acid solution by chemical or electrical stimulation

145 based approach provided accurate analysis of weak acid solution pH.

146 such as limestone and marble, are soluble in weak acid solutions and therefore particularly vulnerabl

147 onization (ESII) method are very similar for weak acid solutions, but with voltage on, the ion abunda

148 e findings help advance our understanding of weak acids sorption by carbonaceous materials.

149 2) the permeability coefficients (P) and the weak acid strength (pK(a)-values) determine the dynamic

150 Here we report that MNL1 regulates weak acid stress responses.

151 rotein kinase are intrinsically resistant to weak acid stress, in that they do not need to spend a lo

152 bility of C. albicans mnl1 cells to adapt to weak acid stress, indicating that Mnl1 and Nrg1 act anta

153 e element (SLE) that imposes Mnl1-dependent, weak acid stress-induced transcription upon a lacZ repor

154 ationary phase cell death during exposure to weak acid stress.

155 long-term adaptation of C. albicans cells to weak acid stresses and compromises their global transcri

156 hich the central histidine is uncharged, and weak acid substrate anion protonation occurs in the vest

157 ng photobase, with the water solvent and the weak acid succinimide.

158 Weak acids such as 4-methoxybenzoic acid and 2-pyridone

159 Protonation occurs even with weak acids such as acetic acid, and the process remains

160 rate is restored upon adding azide or other weak acids such as formate and cyanate.

161 For the product aldols, even weak acids (such as ammonium chloride) or protic solvent

162 zenedithiolato)][Fe(CO)3]2 has revealed that weak acids, such as acetic acid, can be used.

163 Weak acids, such as hydroxamic acids, bind in their neut

164 luoroacetic acid, and to a lesser extent, by weak acids, such as water.

165 osed to proapoptotic or pronecrotic doses of weak acid, suggesting that Ras-pathway activation might

166 lective visible-light-driven generation of a weak acid (sulfinic acid, in nitrogen-purged solutions)

167 wim normally and show wild-type responses to weak acids supports the existence of additional chemosen

168 ids to measure pH associated with any of the weak acid systems studied here.

169 ion is the use of fluorinated tetrazole as a weak acid tecton and a tetra-substituted imidazole precu

170 Azide and formate, the smallest of the weak acids tested, are the most potent activators.

171 nts was more recalcitrant (<=23% released by weak acids) than in Fe(III)-reducing systems (~60% relea

172 DNA damage was reduced by incubation with a weak acid that lowers the pHi to the same extent as thro

173 nghaus gas sensor suffers interferences from weak acids that can cross the GPM as gases and change th

174 lification of sour taste and may explain why weak acids that produce intracellular acidification, suc

175 ng anion then weak acid) or stepwise manner (weak acid then strong anion).

176 e, or at room temperature in the presence of weak acids, these complexes epimerize at the stereogenic

177 (X = Cl, 1; X = I, 3), whereas addition of a weak acid to 2 allowed us to intercept the hydrido-halid

178 (cis-1), readily dimerizes on treatment with weak acid to give the 1,2-difurylethylenes, trans- and c

179 o [(Tp)MoFe(3)S(4)(S-p-tol)(3)](2)(-) and by weak acids to [(Tp)MoFe(3)S(4)(SH)(3)](2-).

180 strong hydrogen bond donors but sufficiently weak acids to avoid deleterious protonation of the trans

181 l scheme using optical fingerprints from all weak acids to measure pH associated with any of the weak

182 ion factors and does not require the classic weak-acid transcription factors War1 or Msn2/Msn4.

183 onsidered in spectroscopic investigations of weak acid transport in vesicular suspensions.

184 ls of only -0.44 to -0.71 V depending on the weak acid used.

185 is region, a substantial rate enhancement by weak acids was clearly evident.

186 this study, Sap C (initially protonated in a weak acid) was inserted into multilamellar vesicles (MLV

187 protonated Sap C (initially protonated in a weak acid) was unable to produce well-oriented POPS bila

188 ses, the separations of both nucleobases and weak acids/weak bases on these gradient stationary phase

189 a strong acid buffer, the CEC separation of weak acids, where dissociation is suppressed, and weak b

190 ere grown in propionate, a membrane-permeant weak acid which acidifies the cytoplasm.

191 buffering components: one weak base and one weak acid which have similar pKa at 25 degrees C (within

192 died, which upon irradiation, changes from a weak acid, with a pK(a) of 7.8, to a strong acid, which

193 basic enough to add another proton from the weak acid without the third electron.