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1 lizer was synthesized using iron salts and a weak base.
2  but not by inducing exchange or acting as a weak base.
3 colored allenic structure upon addition of a weak base.
4 les was corrected with low concentrations of weak base.
5 anic compounds (IOCs) such as weak acids and weak bases.
6 e pH that favors accumulation of cations and weak bases.
7 nts is abnormally sensitive to inhibition by weak bases.
8 iggered reactions of strong (photo)acids and weak bases.
9 fficking defects, which can be alleviated by weak bases.
10 nal evidence that carbon nanotubes behave as weak bases.
11  sensitive to pH in the manner observed with weak bases.
12  role in renal secretion of a broad array of weak bases.
13  proton pumping but not by endosome-targeted weak bases.
14 ubating CF respiratory epithelial cells with weak bases.
15 acid (HPTS) and changed using weak acids and weak bases.
16 rong bases (0.2 and 0.5 M KOH) and best with weak bases (0.01 and 0.2 M KOH).
17 hat in its variant forms can transport these weak-base 4-aminoquinoline drugs out of this acidic orga
18   Incubating unfertilized sea urchin eggs in weak bases activates nuclear centering, DNA synthesis, a
19 , but later experiments indicated that these weak bases also lead to increases in reduced pyridine nu
20 sassembly, since treatment of cells with the weak base ammonium chloride diminished the apoptotic res
21    Incubation of HeLa and CHO cells with the weak base ammonium chloride or the ionophore monensin, w
22  manner by treatment with the lysosomotropic weak base ammonium chloride, which raises intravesicular
23 n A and bafilomycin A1 or the lysosomotropic weak base ammonium chloride.
24 ut in a more effective way than weak acid or weak base and boosts mass spectrometry responses (signal
25 ning two effective buffering components: one weak base and one weak acid which have similar pKa at 25
26 rtments are not dependent on the presence of weak bases and are not inhibited by bafilomycin A1.
27 her perturbants of intraorganelle pH such as weak bases and inhibitors of V-type ATPases.
28  excess unlabeled transferrin and reduced by weak bases and metabolic inhibitors.
29 te intravesicular trapping of chloroquine (a weak base) and do not account for reduced drug accumulat
30 odified dibenzylideneacetone (dba) ligand, a weak base, and a strong oxidant are critical for obtaini
31 and wastewater are amphoteric, weak acids or weak bases, and, thus, their properties depend on local
32  exchange, SBA) to a tertiary amine version (weak base anion exchange, WBA) to determine the role of
33 g acid cation exchangers and strong base and weak base anion exchangers were evaluated as stationary
34 some de-acidification with, for example, the weak-base anti-malarial drug chloroquine prevents exogen
35 vant to the protonation and sequestration of weak base anticancer drugs such as doxorubicin.
36          In this issue of Neuron reveal that weak base antipsychotic drugs inhibit presynaptic functi
37 acids, where dissociation is suppressed, and weak bases as cations is possible.
38 ements, however, show that these amphipathic weak bases bind to phospholipid vesicles at the same con
39    The buffers in use contain a weak acid or weak base buffered by a compound with a dissimilar pK.
40                                  Exposure to weak bases can also inhibit aggregation and cell-type sp
41 n of proton donors in the form of protonated weak bases can be highly beneficial; (iii) the addition
42  demonstrate that the addition of aniline (a weak base) can control the acidity of PEDOT:PSS and enha
43  owing to the presence of hydronium ions and weak base cations.
44 e a cytotoxin, VacA, that in the presence of weak bases, causes osmotic swelling of acidic intracellu
45 e presence of an excess concentration of the weak base, CH(3)COOLi.
46 ontained a significant, additional amount of weak base character, about the same as the strong base i
47                                              Weak base chemotherapeutic drugs (e.g., anthracyclines a
48 to favor metastatic spread and resistance to weak base chemotherapeutic drugs.
49 orts that tamoxifen causes redistribution of weak base chemotherapeutics from acidic organelles to th
50               Drug-resistant cells sequester weak base chemotherapeutics in acidic organelles away fr
51 proto-ionophore monensin (10 microM) and the weak base chloroquine (40 microM) inhibited activation.
52                                          The weak base chloroquine promoted the release of HIV-1 Tat
53                                          The weak base chloroquine strongly inhibited (125)I-gp120 pr
54 MHC class I molecules was insensitive to the weak base chloroquine, but was blocked by peptide aldehy
55 tments that raise intragranular pH, e.g. the weak base chloroquine, the ionophore monensin and the va
56 ethyl aminomethane acts by increasing plasma weak base concentration and weak cations.
57              It has also been shown that the weak base Cs2CO3 can be employed with ligand 3, allowing
58                               The use of the weak base Cs2CO3 in Pd-catalyzed carboamination reaction
59     Dowd and colleagues have proposed that a weak base (cysteine) produces a strong base (oxygenated
60  cultured mammalian cells in the presence of weak bases (e.g., ammonium chloride), VacA induces the f
61          In this study, we demonstrated that weak bases (e.g., carbonates and phosphates) are able to
62                       Similarly, amphipathic weak bases (e.g., sphingosine) that reverse the negative
63 o a cocurrent receptor stream of water (or a weak base, e.g., dilute hydroxylamine), flowing through
64          These results support the idea that weak bases exert their effects by inhibiting acidificati
65 n analysis (MSFIA), with a selective resin ((weak base extraction chromatographic (WBEC) resin) enabl
66 adult Schistosoma mansoni by incorporating a weak base functional group in these compounds.
67                                              Weak base functional groups were not required for high a
68 ication of CO2 at constant pHo or removal of weak bases, greatly increased phasic contractions.
69 wing in vivo administration, supporting the "weak base hypothesis" that amphetamine reduces synaptic
70                 Varenicline was trapped as a weak base in acidic compartments and slowly released, bl
71 e reduced accumulation of protonated CQ as a weak base in the digestive vacuole of the erythrocyte-st
72                   In contrast, strengthening weak bases in the helix also interferes with splicing an
73                 Lactone enols are moderately weak bases in water with pK(BH) in the range of 3.9-8.1,
74                                 Some organic weak bases induce a detachment from inner lysosomal memb
75                         The pathway by which weak bases influence development is not understood.
76 lso including Zn(2+)) by using weak acid and weak base ion-exchange resins in the presence of ameloge
77 itic chloroquine accumulation mechanism is a weak base "ion-trapping" effect whereupon the basic drug
78 ng development, and the accumulation of this weak base is believed to be responsible for inhibiting f
79 eceptors, we examined whether [(11)C]dLop, a weak base, is ionically trapped in acidic lysosomes.
80                       First, as a lipophilic weak base, it partitions into acidic vesicles, resulting
81 ituents, a Cu(I) carboxylate complex and the weak base KOAc.
82 the ammonium analog [(14)C]methylammonium, a weak base, led to the proposal that members of this fami
83                             We conclude that weak bases like ammonia, potentially generated during H.
84 e-supported palladium(II)-aryl complex and a weak base, lysine amino groups underwent C-N bond format
85 ched by the addition of a membrane-permeable weak base, methylamine.
86 lds of the desired compounds, along with the weak base, NaOAc, in anisole at 120 degrees C.
87 even crucial unless protonation of extremely weak bases needs to be achieved.
88                               In contrast, a weak base (NH3) changes pHo with reverse dependence on t
89                           Application of the weak base NH4Cl alkalinized the cytosol and caused a dos
90  inhibited from entering cells by either the weak base NH4Cl or the cysteine proteinase inhibitor E-6
91 operty was demonstrated using lysosomotropic weak bases (NH4Cl, chloroquine, or methylamine) that inc
92 a2+]i induced by nigericin, monensin, or the weak base, NH4Cl, in the nominal absence of extracellula
93  brain-wide and subcellular distributions of weak-base nicotinic receptor ligands.
94  3.9-8.1, whereas the lactones are extremely weak bases of pK(BH) in the range of -10.5 to -17.4.
95              All recommendations issued were weak based on the quality of data.
96 parations of both nucleobases and weak acids/weak bases on these gradient stationary phases have been
97        However, most tests of neutrality are weak, based on static system properties such as species-
98 f intracellular compartments (lysosomotropic weak bases) on the infection and replication of Sindbis
99                          Alkalinization with weak bases or by removal of CO2 inhibited contractions.
100 everse Watson-Crick orientation, and forms a weak base pair with a thymine of the opposite strand.
101  possible contribution to specificity is the weak base pairing and inherent instability of damaged si
102 ents with reporter assays, we establish that weak base pairing in both seed and 3' regions is require
103 able DNA stabilizing ability for maintaining weak base pairing interactions to facilitate primer exte
104 ew mechanistic insights into the kinetics of weak base PET imaging ligands and the subcellular mechan
105                             SOM sorption for weak bases (pK(a) 4.5-7) was stronger at pH 4.5 than at
106 0.05) further allowed us to develop a simple weak base-promoted N-alkylation method and a stereoselec
107 energy sampling to study the permeation of a weak base propranolol (PPL), and evaluate the impact of
108 on study of a weak acid (benzoic acid) and a weak base (propranolol) and their sodium and hydrochlori
109 ifferent from previously studied strong acid-weak base reactions.
110                                Hydrolysis by weak base renders AE permanently non-chemiluminescent.
111            Complexing this cluster with very weak bases reveals a redshift of 37 cm(-1) in the Au-H v
112 on of membrane impermeable ionic form of the weak base small molecules.
113                          Exposing cells to a weak base such as primaquine increases the pool of inter
114 total alkalinity of a sample that contains a weak base such as Tris (pK(a) = 8.2) is presented here f
115 thelial cells, but the presence of exogenous weak bases such as ammonium chloride (NH(4)Cl) enhances
116 of traditional mixed superacids to protonate weak bases such as CO2 can be traced to a competition be
117 eaction proceeds under mild conditions using weak bases such as Cs(2)CO(3) or K(3)PO(4).
118 grow in the presence of ammonium chloride, a weak base that blocks acid-dependent proteolysis of vira
119 grow in the presence of ammonium chloride, a weak base that blocks acid-dependent proteolysis of vira
120                  Ammonium chloride (AC) is a weak base that blocks disassembly of reovirus virions by
121 d in cells treated with ammonium chloride, a weak base that blocks viral disassembly.
122 se removal is also blocked by chloroquine, a weak base that neutralizes the acidic pH of the vacuole.
123                                        For a weak base that was tested in eluent pH either above or b
124                   All of these compounds are weak bases that accumulate in the acidic space generated
125 VMAT1-independent mechanism; they may act as weak bases that passively permeate secretory vesicle mem
126               LysoSensors are cell-permeable weak bases that selectively accumulate in acidic vesicle
127        Moreover even in the absence of added weak bases these mutants are delayed in aggregation and
128                 A pyridine N-oxide acts as a weak base to facilitate the formation of an alkynylgold
129  a strong base to recover xanthophylls and a weak base to recover astaxanthin--should be used for max
130  acetone, pyrrole, indole, or acrolein and a weak base to stereoselectively form 1,2-dihydropyridine
131 obenzene and in the presence of K(3)PO(4) as weak base, to afford the corresponding unsaturated amino
132                                          The weak bases trimethoprim and 4-phenylpyridine showed a si
133 ge in pHi was neutralized by addition of the weak base trimethylamine (TMA).
134  superfusion with 3 mM concentrations of the weak bases trimethylamine (TMA), ammonium chloride (NH4C
135 ixture of particles coated by weak acids and weak bases under externally controlled oscillations of p
136 utral reference compound, (v) the protonated weak base was strongly affected by different electrolyte
137                                  Trapping of weak bases was utilized to evaluate stimulus-induced cha
138                                        Among weak bases we screened, catalytic (10-20 mol %) 1,4-diaz
139 measurements, whereas release of fluorescent weak bases, which accumulate selectively within eosinoph
140  acid, the presence of low concentrations of weak base will prevent the effect of stray light.
141         Chloroquine (CQ) is a lysosomotropic weak base with over 60 years of clinical use for the tre
142         A cancer candidate, compound 1, is a weak base with two heterocyclic basic nitrogens and five
143     Hexafluorotropone was found to be a very weak base, with a conjugate acid pK(a) of -6.2 +/- 0.5.

 
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