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1 Electrode (IAME) as the filtering capacitor, wherein 3-D printed lines of varying wt% of PEDOT:PSS hy
2 used for the pathway's enrichment analysis, wherein 37 enriched signalling pathways were obtained.
4 vicinal sp(3) C-H bonds has been developed, wherein a beta amine and gamma iodide are incorporated o
5 The resulting structures are brush polymers wherein a biomolecular graft is positioned at each monom
7 lates of consciousness is binocular rivalry, wherein a constant visual stimulus evokes a varying cons
8 remains difficult due to lack of modularity, wherein a device's output does not depend only on its in
9 we generated male and female transgenic mice wherein a disrupted cGMP-gated channel (CNG) gene can be
11 ropose a branching model of mTEC development wherein a heterogeneous pool of transit-amplifying cells
12 d spectroscopic evidence of a tunable system wherein a HO...pai interaction switches incrementally to
14 benefit, and an "effect-modeling" approach, wherein a model is developed on RCT data by incorporatin
15 ors are rotators that are activated by light wherein a molecular subcomponent rotates unidirectionall
16 HTE approaches: a "risk-modeling" approach, wherein a multivariable model predicts the risk for an o
17 ypertrophy is a context-dependent phenomenon wherein a myriad of biochemical and biomechanical factor
18 rmation proceeds via a radical-chain process wherein a nickel(I) complex serves as the chain-carrying
19 eatment effects as median risk ratios (RRs), wherein a null effect equals 1, with 95% credible interv
20 increasing demand for multiorgan transplant, wherein a patient with multiorgan disease receives >1 or
21 effect; instead, a hierarchical order exists wherein a primary site, a secondary site, and three tert
22 adian clock mechanism of protein homeostasis wherein a sacrificial pool of collagen maintains tissue
23 an be used to create single-electron devices wherein a single redox-active cluster is connected to tw
24 e evidence supports a multifaceted mechanism wherein a small amount of an initially formed metal hydr
26 scriptional chemoenzymatic labeling platform wherein a terminal uridylyl transferase (TUTase) was rep
28 chronic (metabolic endotoxemia) pathologies wherein aberrant TLR4/MD2 activation has been implicated
29 ther, these data are consistent with a model wherein activation of ASIC1A, particularly in neurons, i
30 ohol-exposed neural fold-stage chick crania, wherein alcohol causes facial deficits recapitulating th
31 dical relay chaperone strategy was designed, wherein an alcohol was transiently converted to an imida
33 and incorporated into a biochemical pathway wherein an initiator complex promotes trichome fate in a
34 on ignores extreme antagonistic interactions wherein an otherwise deleterious perturbation compensate
35 first time a circuit motif for PFC function wherein anatomically non-overlapping output pathways coo
37 fficient to generate a form of active matter wherein asymmetric filament disassembly preserves filame
39 e of "bacterial magneto-convection" results, wherein bacterial plumes emerge spontaneously perpendicu
40 es while showing expression differentiation, wherein BjuA.Galpha1 was the highly abundant transcript
41 ingle-nucleotide homology at the break site, wherein both ends of the discontinuous template strand a
43 ferromagnetic semiconductor Li(1+y)(Cd,Mn)P, wherein carrier is doped via excess Li while spin is dop
45 model of disseminated SEM cell-derived ALL, wherein CD19+ cells closely associated with nestin+ MSCs
46 a 'virtual-reality system for single cells', wherein cell behavior directly controls its ambient envi
47 g area of focus is on engineering consortia, wherein cell subpopulations work together to carry out a
50 stablished that EMT is a multistable process wherein cells exhibit and switch among multiple phenotyp
51 at similar final sizes [1-3], and "adders," wherein cells increase in size a fixed amount per cell c
52 sion in bacteria and yeast through "sizers," wherein cells of varying birth size divide at similar fi
53 ddition of the alkoxide to the aromatic ring wherein charge on the aromatic system is stabilized by t
54 ter 'superclusters' create nano-environments wherein clustered RFs activate target genes, providing a
55 en, but also may provide an opportune window wherein cognitive or behavioral interventions could be i
56 ependent patterns is microbial interactions, wherein community composition at a given time point affe
57 multimicrobial respiratory tract infections, wherein control of inflammatory exacerbations is a major
58 cur at a well-defined three-phase interface, wherein conventional heterogeneous catalyst layer struct
59 advective component to TT content exchange, wherein cyclic deformation of TT during diastolic stretc
60 coccus's nearest relative, Prochlorococcus - wherein decreasing genome size has coincided with a stro
62 hange of synaptic AMPARs in V1 L2/3 neurons, wherein deep synapses are potentiated more than superfic
63 e data presented are consistent with a model wherein defective MntABC results in decreased cellular C
64 ar brown adipose tissue (IBAT) mitochondria, wherein DeltaPsi is intrinsically low because of uncoupl
65 ght be useful in large epidemiologic studies wherein detailed structural assessment of osteoarthritis
67 exists with autoimmune disease development, wherein diminishing pathogenic effectors may benefit the
68 of the two key immunodominant IAV antigens, wherein direct infection drives optimal nucleoprotein (N
69 role of the cholangiocyte apical glycocalyx, wherein disruption of the glycocalyx with neuraminidase
70 osons includes a reverse transcription step, wherein dsDNA is synthesized from genomic RNA for subseq
71 the treatment of neuropsychiatric disorders wherein dynorphin is thought to contribute to the underl
72 the only known steady-state growth condition wherein E. coli significantly deviates from the adder, b
74 tions between agents as a best-response game wherein each agent negotiates to maximize their own util
75 through a sequential immunization protocol, wherein each new immunization optimally increases the pr
77 graphene to effectively migrate step-by-step wherein each step involves reversible bond breaking and
78 limited to a "one-color-one-target" approach wherein each target is encoded with a specific fluoresce
79 bivalent anti-HER2 antibodies were prepared wherein each varied in the orientation of the fusion dom
80 fine a mechanism for acneiform skin toxicity wherein EGFR/MEK inhibitors cooperate with the skin comm
81 ates toxicity, we designed PrP(C) constructs wherein either the cis-interaction or alpha-cleavage are
82 response is closely tied to flexoelectricity wherein electric polarization and electromechanical resp
83 h AD by generating stable HEK293 cell lines, wherein endogenous APH-1A and APH-1B expression was sile
84 advent of non-Hermitian topological systems-wherein energy is not conserved-has sparked considerable
86 an automation-enabled large-scale experiment wherein Escherichia coli strains were evolved in paralle
87 in body contains 10 disease-focused sections wherein every small molecule component utilized as part
88 itive operation performed by the hippocampus wherein existing mnemonic representations are retrieved
89 has traditionally been driven by empiricism, wherein experimentalists attempt to qualitatively recogn
90 hanisms of hyperglycemia-induced retinopathy wherein extensive proangiogenic alterations in blood ves
91 ation of the electrode is achieved at -1.2 V wherein Fc(+) is reduced to Fc thereby facilitating As d
92 oduction of T. gondii occurs only in felids, wherein fertilisation of haploid macrogametes by haploid
93 This perspective outlines clinical scenarios wherein findings on technetium-labeled cardiac scintigra
94 the TIRADS model referenced in Kwak et al., wherein fine-needle biopsy is recommended for TIRADS 4A
95 r type A receptor at the so-called T6' ring, wherein five threonine residues line the permeation path
97 tion of lithospheric thickness and rheology, wherein geometrically-regular, polygonal-shaped tessella
98 nding to 180 unique proteins were identified wherein >24% of them were described lentil allergens.
100 involves a reconfiguration of the epigenome, wherein H3K27ac and H3K9ac affect disease pathways by dy
101 Our results are consistent with a model wherein heme release from HasAp to the N-terminal plug o
104 acute hyperglycemia-induced hyperfiltration wherein increases in luminal glucose at the macula densa
105 ertebrate NMD is a complex, branched pathway wherein individual branches regulate specific mRNA subse
106 aling is a prevalent theme in cancer biology wherein individual molecules and pathways can have multi
107 us pneumoniae is a major cause of pneumonia, wherein infection of respiratory mucosa drives a robust
108 ntiation in complex and dynamic environments wherein instructive signals fluctuate on various timesca
109 chronic phase of gammaherpesvirus infection, wherein IRF-7 restricts the establishment of viral laten
110 stingly, p53 is frequently mutated in tumors wherein iron is often accumulated, suggesting that mutan
111 st a model of BP utilization by mutant SF3B1 wherein it is able to utilize non-consensus alternative
112 formation for the alphaN region of free Cre, wherein it packs in cis over the protein DNA binding sur
113 ature generalized to two depression samples, wherein it reflected general antidepressant medication r
114 c mapping with in vitro and in vivo studies, wherein it revealed timely tumor drainage and afforded d
116 the order of mutations at the pathway level, wherein it uses a probabilistic method to characterize t
117 PR as a broad-spectrum compensatory response wherein LBS and proteotoxic stress deploy divergent tran
119 h inhibitory actions of LGP2 binding to MAVS wherein LGP2 translocation to mitochondria releases MAVS
120 mammalian mechanism for membrane homeostasis wherein lipidome remodeling in response to dietary lipid
121 by selenium in FeMoco affords a unique probe wherein local Fe-Se interactions can be directly interro
122 ly, these results suggest a novel mechanism, wherein loss of type I receptor of TGF-beta triggers pro
124 ltimetallic phosphide CoMP(x) nanorods (NRs) wherein M can be controlled to be Fe, Ni, Mn, Cu, and th
125 (Acyrthosiphon pisum) male wing dimorphism, wherein males exhibit one of two morphologies that diffe
126 assembly of the CARMA1-BCL10-MALT1 complex, wherein MALT1 acts as (a) a scaffold to recruit componen
127 ic review was the threat of publication bias wherein many countries may not have documented their exp
128 were severely affected in feather follicles wherein MDV is shed, providing important information on
129 emerging paradigm for scientific discovery, wherein measurement instruments are augmented with decis
130 ed by incorporation of a hierarchical scheme wherein mental/emotional infrastructure interacts across
131 Neonatal mouse models of RSV were employed, wherein mice infected at 6-7 days of life were analyzed
132 ain solutions was suitable for spray drying, wherein microcapsules with smooth and spherical morpholo
134 drial hypothesis and offer a new perspective wherein mitochondria are analyzed not only from the OxPh
135 vel translation regulation signaling circuit wherein MNK1-eIF4E activity drives mTORC1 via control of
137 l-molecule interfaces enables a new paradigm wherein molecule-quantum dot constructs are used to syst
138 ental stimulus-response behaviors in biology wherein motile microorganisms sense light gradients to s
139 a host of human diseases, especially cancer, wherein mucin expression and glycosylation patterns are
140 tegy termed selective organ targeting (SORT) wherein multiple classes of lipid nanoparticles are syst
142 ) imaging reveals a crystalline intermediate wherein N-terminal nucleation domains exhibit motional d
144 use lung is established by domain branching, wherein new branches form laterally off the side of an e
145 ucture as opposed to unfluorinated analogues wherein NH...OC hydrogen-bonding interactions force benz
146 se in day and night temperature is observed, wherein night temperatures are increasing at a higher pa
148 vantages of 3D spheroids over 2D monolayers, wherein novel therapeutic targets were identified, such
150 iate progenitors during brain tumorigenesis, wherein oligodendrocyte-progenitor intermediates are abu
151 urce both in monoculture and in polycultures wherein on-going eco-evolutionary community dynamics wer
152 fy a new paradigm of multiscale measurement, wherein one can observe and probe macroscale and ecologi
153 the configuration Terfenol-D/CoFeB/Ni/PMN-PT wherein one desired mode exhibits a much higher tunabili
154 vel vicarious social defeat stress procedure wherein one mouse witnesses the physical defeat bout of
155 evealed two excited states of pyrene excimer wherein only one is directly involved in the resonance e
156 Further, we postulate a Goldilocks model, wherein optimal glycan interactions can influence the CN
157 n arises from edge-initiated photooxidation, wherein oxidative attack is powered by photogenerated an
160 onstructed a "disease-disease" network (DDN) wherein pairs of diseases were connected on the basis of
161 l environment (VE) was created at room-scale wherein participants traversed a grid of ice blocks plac
164 knockout resulted in sex-specific responses wherein PDYN knockout decreased alcohol drinking in both
167 We report an edge-stabilization strategy wherein phosphine oxides passivate unsaturated lead site
168 aying around the gap, suggesting a mechanism wherein Pol recognises a pre-bent, partially-melted conf
169 of the H3K27M inhibitor and support a model wherein PRC2 becomes trapped at H3K27M-H3K27me3 boundari
171 ned by developing a seeded growth synthesis, wherein preformed Ag nanoparticles are used as nucleatio
172 n biological reaction in all domains of life wherein prenyl diphosphate donors transfer prenyl groups
173 for a combinatorial CTD phosphorylation code wherein previously installed modifications direct the id
174 dition was reflected in blood transcriptomes wherein prominent IFN signatures were only seen in criti
175 l Revolution was a positive feedback process wherein prosperity induced prosperity-promoting preferen
177 ese classes reveal a functional organization wherein putative dorsal areas show specialization for vi
178 ifically interested in the olfactory system, wherein recent experimental studies have reported the ex
179 y in cells lacking the lipidation machinery, wherein receptor-mediated clustering of upstream autopha
180 e temperatures often lead to coral bleaching wherein reef-building corals lose significant numbers of
181 ase by reducing the penetrance of risk loci, wherein resilience and risk loci operate orthogonal to o
182 ss commonly used variation on this approach, wherein resistant cells are selected by immediately expo
183 The visual circuit is topographic [5, 6], wherein retinal neurons target and activate predictable
184 mechanism in RF-mediated autoimmune diseases wherein RF may act as a precursor from which the ACPA re
185 mTOR-responsive neuronal autophagy pathway, wherein RILP integrates the processes of autophagosome b
190 this correlate consists of a population code wherein single cells multiplex representation of the con
191 as individual complexes, supporting a model wherein sister cohesion is mediated locally by a single
192 ver 1,600 individuals, we describe a pathway wherein sleep fragmentation raises inflammatory-related
194 is that a mechanistic framework has emerged, wherein Small Auxin Up RNA (SAUR) proteins regulate prot
195 have demonstrated size-based ion selectivity wherein smaller hydrated ions are preferentially electro
196 developmental defects, we engineered a mouse wherein Smc5 is conditionally knocked out (cKO) in the d
198 context of plant pathogens and their hosts, wherein specific host proteins 'guard' central cellular
199 t localization dynamics of SpoVM and SpoIVA, wherein SpoVM displays a longer residence time on the fo
200 ng from the nose down towards the lower HRT, wherein stationary cells interact with IAV which moves w
201 our previous molecular dynamics simulations wherein substrate binding to an allosteric site remote f
203 wounds as portals of entry into host tissue, wherein surface adhesins interact with the extracellular
204 n occurring through a positive-feedback loop wherein surface-deposited C3b participates in convertase
205 uniquely complex sociotechnical work system wherein surgical successes prevail despite pervasive saf
206 esults demonstrate a novel delivery paradigm wherein systemically injected cells release microparticl
207 support a general tau aggregation mechanism wherein tau's inherent surface activity and favorable in
209 is of a new heterocyclic system is described wherein the 2H-bis([1,2,3]triazolo)[5,1-a:4',5'-c]isoqui
210 ize spatial-coincidence in the third series, wherein the 5d(10) core approaches the valence 6s orbita
211 f the optimal mass transport (rOMT) problem, wherein the advection/diffusion equation is the only a p
212 ant set of experiments that reveal a pathway wherein the ALDH2 rs671 mutant is phosphorylated by AMPK
213 be a four-component variant of this process, wherein the alkyl halide is generated in situ, thus obvi
215 active cation-transporting principal cells, wherein the aquaglyceroporins localize to opposite plasm
216 odel for PCV2-endosomal membrane interaction wherein the ARM peptide externalizes from the capsid, it
217 due to an unusual beta-elimination reaction, wherein the azide anion acted as the leaving group.
219 effect spectroscopy (ROESY) NMR experiment, wherein the beta-d-glucose moiety of 1 was used as an in
221 s (cargo) and eventually fuse with lysosomes wherein the cargo gets degraded and resulting simpler bi
222 prompt us to present a revised model of CSS wherein the CCSSD:NTSD complex forms prior to ferric-sid
223 er provides a plausible regulatory mechanism wherein the cellular fate of tRNAs can be switched from
224 via a convergent fragment coupling approach, wherein the central seven-membered ring is synthesized a
226 a novel mechanism, supported by experiments, wherein the conserved Walker A arginine 'toggles' betwee
227 iors of the crystalline phases were observed wherein the cubic iron oxide crystals laterally expanded
228 into meaningful metabolic benefits in vivo, wherein the dynamics of insulin signaling and receptor r
229 ode separated by a porous solid electrolyte, wherein the electrochemically generated H(+) and HO(2) (
230 istinct yet potentially overlapping contexts wherein the elusive molecular function of the Memo domai
231 l, the resulting paradigm comprises a system wherein the extent of band bending induced by metal ion
232 1)(II)-N(4) sites via "noncontact pyrolysis" wherein the Fe precursor is not in physical contact with
233 ibe herein a path-dependent "history" effect wherein the film morphology generated in the second step
234 s suggest a mechanistic model for extrusion, wherein the formation of unilamellar vesicles involves c
235 These results support an emerging hypothesis wherein the H1 CTD serves as a nexus for signaling in th
237 ss of electric-charge-induced self-assembly, wherein the internal built-in field in the polar materia
238 degeneration exhibited a strong relationship wherein the IS/OS loss was 1.6-fold greater than that of
239 represent multiple pathways within the lens wherein the isomerization of aspartate residues in cryst
240 eae deploys a unique immune evasion strategy wherein the lacto-N-neotetraose termini of lipooligosacc
241 eability and structure-efflux relationships, wherein the linker length, stereoinversion, N-methylatio
242 tionally locked three-dimensional structures wherein the lone pairs of electrons on oxygen and nitrog
243 rmline partly by "transcriptional scanning," wherein the majority of genes are transcribed and theref
244 cal analyses suggest an electronic structure wherein the manganese atom remains Mn(III) and the OIM l
246 ceptor ectodomain in a T-shaped conformation wherein the membrane-proximal domains converge and conta
247 structures of a MdfA mutant E26T/D34M/A150E, wherein the multidrug-binding and protonation sites were
248 R-RAS signaling, and an AGO2-dependent phase wherein the mutant KRAS-AGO2 interaction is critical for
249 Rpt1 protein complexes into heavy particles, wherein the nascent protein complexes escape ribosome qu
250 oupling regime for many molecular aggregates wherein the nonequilibrium environment phonons play nont
251 These findings support a model mechanism wherein the NTD mediates allosteric coupling to ion grad
252 hibit a form of closed mitosis (dinomitosis) wherein the nuclear envelope (NE) invaginates to form on
253 he consequence of common-envelope evolution, wherein the original orbit is enveloped during the red g
254 d on previous research to synthesize a model wherein the OT, which may be more appropriately termed t
255 at background pressures [Formula: see text], wherein the overall energy in ions [Formula: see text] i
256 tic and diffusive limits for magnetophoresis wherein the paramagnetic particles either aggregate near
257 ransition-metal cobalt has been demonstrated wherein the pivaloyl group acts as a weakly coordinating
258 of NPC1 using Trojan horse liposomes (THLs), wherein the plasmid DNA is encapsulated in 100 nm pegyla
260 cules is of interest in medicinal chemistry, wherein the preparation of structural variants of known
261 the Fenton reaction has been widely studied, wherein the primary species is the hydroxyl radical (OH)
262 ssembly, catalysis, and information storage, wherein the primary structure begets complex chemical pr
263 nted together with chemical kinetic modeling wherein the rate constants employed have been calculated
264 -C(O) bond cross-coupling reactions to date, wherein the reactivity is driven by ground-state destabi
265 e to the lower-symmetry Frank-Kasper phases, wherein the reconfiguration of the system into polyhedra
266 g economists, a comparable contrast is found wherein the reductionist shareholder primacy theory most
267 n this new pyridazine elimination mechanism, wherein the roles are reversed, a trans-cyclooctene acti
269 s relevant to the polypharmacology paradigm, wherein the same drug (methotrexate) binds to multiple n
270 d treatment of protein misfolding disorders, wherein the stabilisation of disease-associated states p
272 d expand the application scope to conditions wherein the trans-cyclooctene has limited stability.
273 enomenon observed in many bacterial genomes, wherein the two replication strands of the same chromoso
274 l responses under several stress conditions, wherein the unusual sensitivity to Mg(2+) can be indepen
275 est a composite-ligand model of P-Ag sensing wherein the Vgamma9Vdelta2 TCR directly interacts with b
276 and jalapeno pepper (Capsicum annuum) plants wherein the virus protects the plants from the vector of
277 water and associated industries is provided, wherein their unique features and promises are discussed
278 he resulting alpha-substituted NH-ketimines, wherein there is strong C=N -> B(pin) coordination, woul
279 with various advanced metastatic carcinomas, wherein these cells are transitioning between strongly e
280 analytes through a molecular-scale aperture, wherein they are interrogated by electrical or optical m
282 redefined BA signaling in health and disease wherein they may suppress inflammation on the one hand,
285 found to undergo reactions with isocyanates, wherein triflic acid promotes the formation of aromatic
286 chlorides using nickel/photoredox catalysis wherein trimethyl orthoformate, a common laboratory solv
287 ns enabled a radical-polar crossover pathway wherein two distinct electrophiles can be added across a
288 ce of a tandem aptamer arrangement (tandem), wherein two homologous aptamers interact with glycine an
289 dies support a cooperative mode of catalysis wherein two molecules of the urea catalyst engage the su
290 in uniparental inheritance of mitochondria, wherein two of the four spores formed subsequently conta
293 We therefore pursue an experimental strategy wherein we control local CO(2) availability on a Cu cata
294 The first is an intermolecular approach, wherein we designed several structural isomers to maximi
295 ensity functional theory (DFT) calculations, wherein we discerned high correlations amongst their cal
296 gy that we term learning-in-templates (LiT), wherein we first define a series of space group and stoi
297 g-in was used for sub-modulization analysis, wherein we identified 25 modules; ClueGo plug-in was use
298 e complex endogenous gut microbiome of pigs, wherein we resolve 355 metagenome-assembled genomes toge
299 roscopy (SPIM) and FRAP to create SPIM-FRAP, wherein we use a sheet of light to bleach a two-dimensio
300 s, a study using a unique post-mortem cohort wherein whole body autopsy reports and brain tissue were