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1 low pathologists to exclude 65-75% of slides while retaining 100% sensitivity.
2 (YL2) that fails to stimulate HCMV infection while retaining 30 to 80% of the activity of the wt prot
3 onformational distribution of the PTZ units, while retaining a certain degree of rotational freedom o
4  L43A mutation reduces temperature stability while retaining a ground-state structure similar to WT.
5 ance of a previous lower-throughput platform while retaining a high degree of flexibility, potentiall
6  TCRs had improved T cell activation potency while retaining a high degree of specificity.
7 xtract amaranth and quinoa starch from flour while retaining a high protein content, which gives thes
8 n and striking 237 nm effective Stokes shift while retaining a large quantum yield of 0.59.
9 nd differ significantly in helical geometry, while retaining a local conformation similar to previous
10 ses, ricolinostat selectively inhibits HDAC6 while retaining a low and tolerable level of class I HDA
11 ovide a dramatic jump in localized activity, while retaining a low dark-state background remains a si
12 vely lose their toxicity against human cells while retaining a potent antiparasitic activity both in
13 lar IC50 for NF-kappaB inhibition of 0.3 muM while retaining a potent EGFR kinase inhibition (IC50 =
14 oisomerization efficiency could be maximized while retaining a reasonable thermal stability of the me
15 osteric site affinity as compared with BQCA, while retaining a similar level of positive cooperativit
16 EN2) or more (CEN5) alternate CEN haplotypes while retaining a single haplotype at domestication loci
17 ther proteins were washed off with 3 M NaCl, while retaining AChE bound to Hupresin.
18 in during evolution of Drosophilidae lineage while retaining activity.
19  Alcids exhibit exceptional dive performance while retaining aerial flight.
20 ize a flexible loop between helices 3 and 4, while retaining affinity for the hGH receptor, we have e
21 elta(u) for release of acetate up to 7-fold, while retaining all the other excellent properties of th
22 tLX) that virtually eliminates all F results while retaining an excellent proportion of true positive
23  tether, and pendant substituted amido group while retaining an N-methyl group as a site for labeling
24 y and acquire an immunosuppressive phenotype while retaining anti-bacterial and wound-healing propert
25 m doxorubicin-induced neutropenia and anemia while retaining antitumor efficacy.
26  that significantly reduces spurious matches while retaining authentic fusion fragments.
27 P2 and to block its function in cancer, even while retaining binding capacity to WBP2.
28 red binding to heat-shock protein 90 (Hsp90) while retaining binding to RhoGEFs.
29 inflammation and recruitment of innate cells while retaining bioactive TNF to foster neutrophil circu
30 d serum stability and aggregation resistance while retaining bioactivity compared with native insulin
31 minimum detection levels, i.e., <1% to 4-6%, while retaining biochemical potency.
32 the fraction unbound to human plasma protein while retaining biochemical potency.
33 egy for designing proteins of high stability while retaining biological activity since it draws upon
34 in extracts enriched in selected polyphenols while retaining biological activity.
35 -amides to increase solubility and stability while retaining biological activity.
36 ovariates to correct for technical artifacts while retaining biological heterogeneity in genomic data
37 ion properties beneficial for 3D bioprinting while retaining biologically inductive properties suppor
38 ster and undergo spontaneous immortalization while retaining both Arf and p53.
39 hrough synthetic control of the composition, while retaining both structural and functional propertie
40 s that accommodate 25-residue loop insertion while retaining catalytic activity.
41                      Fab fragments of PG102, while retaining CD40 binding, did not induce TRAF degrad
42 and decrease non-specific protein adsorption while retaining cellular biocompatibility, transparency,
43 ons via a non-proliferative two-step process while retaining cellular plasticity.
44 rt organics to CO(2) for delta(13)C analysis while retaining chromatographic resolution.
45 of the total albumin in human plasma samples while retaining close to 100% for two of three therapeut
46 e N (2) expectation values over the ensemble while retaining closure and parallelism.
47 emplated spatially by A-tracts of B-form DNA while retaining coherent energy transfer.
48 ave experienced a temperature rise in summer while retaining cold winters to be dominated by parasito
49 source to avoid X ray-induced sample damage, while retaining comparable acquisition time to the synch
50  electrodes operating in liquid electrolytes while retaining comparable capacity, rate, and overpoten
51 imultaneous detection of both isomeric forms while retaining compatibility with shotgun proteomics.
52  simulations demonstrate computational gains while retaining competitive model selection and classifi
53 ducing the overall cost and time of analysis while retaining detection precision, making it suitable
54 ular Ca(2+), reminiscent of the naive state, while retaining differentiation ability.
55 nable both antigen and adjuvant dose sparing while retaining efficacy.
56 thereby minimizing potential adverse effects while retaining efficacy.
57 cyl and beta-syringyl ether-linked compounds while retaining either beta(R)- or beta(S)-stereospecifi
58 ficantly suppresses the thermal conductivity while retaining eligible carrier concentration over a wi
59 preserve the spatial cues in the speech ENVs while retaining/eliminating them from the TFS.
60 g from intrinsic immuno-stimulatory features while retaining excellent safety profile through the use
61  the active site, permitting novel functions while retaining existing function.
62 ating induction of proinflammatory cytokines while retaining expression of anti-inflammatory and anti
63 n of multiple profibrotic signaling pathways while retaining expression of renoprotective factors.
64 ifically ablated Tcf1 long isoforms in mice, while retaining expression of Tcf1 short isoforms.
65 xtraction solvent was reused for six cycles, while retaining extraction efficiency (up to 28%).
66 FcRn-expressing cellular monolayers in vitro while retaining FcgammaRIIIa binding and function, inclu
67                                              While retaining fidelity, H69 ribosomes exhibit much slo
68 ogation with light and macromolecular labels while retaining fine structure and native biological mol
69 C must thus be specialized to specific tasks while retaining flexibility.
70         The ribozyme was truncated to 96 nt, while retaining full activity.
71 imultaneously select for protease resistance while retaining function-first by degrading the starting
72 ultiple batch effects from t-SNE embeddings, while retaining fundamental information on cell types.
73 f snakes has lost hindlimb enhancer function while retaining genital activity.
74 ated mouse model that is susceptible to DENV while retaining global immune competence.
75  the high level of resistance to oseltamivir while retaining good fitness of viruses carrying I221L v
76 howed significant improvements in solubility while retaining good functional activity but displayed n
77 affold was optimized to subnanomolar potency while retaining good physical druglike properties.
78  improved survival in a mouse model of aGVHD while retaining graft-versus-leukemia effects, unveiling
79 ydroxymethylation prior to hypermethylation, while retaining H3K27me3.
80 can endure multiple rounds of lyophilization while retaining high biological activity.
81 gh breakage of bonds when strain is applied, while retaining high charge transport abilities.
82 lent thermal stability and storage stability while retaining high ductility.
83 f tens to hundreds of samples simultaneously while retaining high efficiency quantitation of microRNA
84 d, and grow to high titer in cultured cells, while retaining high immunogenicity.
85 ffusion, many SENs show remarkable stability while retaining high initial activities even for quite f
86 emission and increase in bandgap is observed while retaining high photoluminescence quantum yield.
87 we are able to suppress dark current density while retaining high responsivity in an ultrasensitive n
88 ial cells, pericytes and astrocyte end feet) while retaining high RNA integrity and protein post-tran
89 false-positive rates (FPRs) for good outcome while retaining high sensitivity for poor outcome.
90 egime is characterized by large fluctuations while retaining high sensitivity to external varying sti
91  system is dominated by internal fluctuation while retaining high sensitivity to externally varying s
92 logy can reach centimeters penetration depth while retaining high spatial resolution in biological ti
93 n sensitivity on novel substrates of kinases while retaining high specificity.
94 ic sensitivity than current 2-tier serology, while retaining high specificity.
95 -affinity monoclonal antibody (mAb) epitopes while retaining high-affinity mAb epitopes.
96     This ion swap led to enzyme inactivation while retaining high-affinity substrate interactions.
97 vity, to enhance selectivity for off-targets while retaining human beta-cell proliferation activity.
98 liferative capacity upon secondary challenge while retaining immediate in vivo effector capabilities:
99  goal of making pigs refractory to infection while retaining important CD163 functions.
100 improve the PPV of a mapping based technique while retaining improved sensitivity and computational e
101 h resolution by removing projection artifact while retaining in-situ flow signal from real blood vess
102 rived cfDNA and short nuclear genomic cfDNA, while retaining information provided by standard dsDNA l
103 ulp3 knockout mice developed cystic kidneys, while retaining intact cilia.
104 recise size with near-neutral surface charge while retaining interior charged groups.
105 ully link the LDH molecule to those surfaces while retaining its activity.
106 physical properties of an engineered protein while retaining its advantages.
107 t state, tantalum flows like a viscous fluid while retaining its crystal lattice and remaining a stro
108 es to roll on, budding off more disciplines, while retaining its own identity.
109 dditional attribute such as biodegradability while retaining its pharmacological potency.
110 ) that utilized rhesus CD4 more efficiently, while retaining its resistance to antibodies and sera fr
111 ally detunes the resonator in transmit mode, while retaining its sensitivity-enhancing properties (tu
112 w does one distill and refine it into images while retaining its significant components?
113  misuse and diversion of daily buprenorphine while retaining its therapeutic benefits.
114 des similar manipulation capabilities as HOT while retaining its unique characteristics.
115 t information in our environment or our mind while retaining limited important relevant contents.
116 to increase bond stability by >40 degrees C, while retaining long-range order and crystal habit.
117 like) batteries show outstanding performance while retaining low cost, multifunctionality, versatilit
118  greatly improve discharged energy densities while retaining low loss and high charge-discharge effic
119 based on only 0.3% of the original data set, while retaining low-intensity isotope peaks, was accompl
120  salt and 47% other dissolved solids removed while retaining majority of the pigment ( approximately
121 mpact of reference bias when analyzing aDNA, while retaining mapping sensitivity and allowing detecti
122 sionality reduction of photoreceptor signals while retaining maximal chromatic information.
123 in principle, they are infinitely deformable while retaining metallic conductivity.
124 icant reduction in the computational burden, while retaining model accuracy and performance, practica
125 sulted in an increased cellulose hydrolysis, while retaining more than 70% functional stability.
126 mbly is a reduced representation of raw data while retaining most of the original information.
127 n with DSM-IV alcohol dependence (r(g)=0.82) while retaining most subjects.
128 cally incorporating long-term climate change while retaining much of the predictive power of a stable
129 nces allow electronic properties to be tuned while retaining nanofibrillar morphologies similar to th
130 in silica-core-gold-shell nanoparticle size, while retaining near-infrared plasmon resonance, and kee
131  deficient in its ability to bind Gbetagamma while retaining normal calcium-dependent Syt1 binding to
132 eered to reduce APC-associated bleeding risk while retaining normal cell-signaling activity, have sho
133                                              While retaining normal systemic iron levels, this model
134 transition (MET) and led to multinucleation, while retaining nuclear AR.
135 ormance because they learn new skills faster while retaining old skills more and because they have a
136  CRISPR GUARD reduces off-target mutagenesis while retaining on-target editing efficiencies with Cas9
137 voided and superior miscibility is provided, while retaining optimal pi-pi stacking to warrant effici
138 mproves the rank of near native predictions, while retaining or even improving the numerical efficien
139 ple mutations significantly reduce synergism while retaining other wild-type kinetic properties.
140 us RdRPs can result in functional innovation while retaining overall protein fold and quaternary stru
141 reducing the amount of presented information while retaining pathways of interest.
142 , which undergoes plus-end-directed movement while retaining physiological cargo interactions in the
143 al magnetic moment into an electrical signal while retaining picosecond temporal resolution.
144 e biased towards mesoderm and endoderm fates while retaining pluripotency.
145 the polar surface area of the P3 substituent while retaining polarity in the P2' side chain.
146 activity of HIV-1 RT in the micromolar range while retaining potency against RT variants carrying one
147 crease solubility and enable dose escalation while retaining potency.
148 ity and plasma-protein binding were improved while retaining potent anti-pseudomonal activity in vitr
149  that is devoid of its natural neurotoxicity while retaining potent oncolytic activity.
150 users through the steps of data integration, while retaining powerful features for more experienced u
151 pid-onset, long-term blockade of the channel while retaining pro-excitatory properties.
152 ty in order to reduce unwanted side effects, while retaining procognitive effects.
153  plausible time-sensitive physiologic states while retaining prognostic information in a dose-depende
154 f gamma oscillations at the stimulation site while retaining propagating waves of gamma oscillations
155 eoside and its ability to replace G residues while retaining proper folding.
156 ng helicase and polymerase encoding domains) while retaining protein coding.
157 e the production cost of V(3.5+) electrolyte while retaining quality that is adequate for high-perfor
158 r exciton functionalities by at least 10(4), while retaining quantum efficiencies above 50%, and demo
159 rotected and emissive configurations in situ while retaining qubit-qubit interactions, opening up pos
160 de polymorphism-based IBD detection methods, while retaining reasonable accuracy for IBD tracts as sm
161 folding simulations would be more economical while retaining reasonable accuracy, and provide feedbac
162 d coverage of the elderly improves outcomes, while retaining resources for detected cases provides fu
163 T2:ERG and PCA3 can avert unnecessary biopsy while retaining robust sensitivity for detecting aggress
164 eased d of the base alloy from 729 to 740 nm while retaining Rq from 1 nm to 3 nm.
165 ) Y37P exhibited enhanced antagonism of AMY1 while retaining selectivity.
166 imized contribution from white matter signal while retaining sensitivity in detecting gray matter sig
167 ide, and pomalidomide on LPM differentiation while retaining sensitivity to another known limb terato
168 lling strategy for reducing their complexity while retaining several desirable benefits such as activ
169 s for (99m)Tc-labeled MPS is highly feasible while retaining short imaging protocols.
170 ion and facilitates extracellular secretion, while retaining signaling capacity.
171 rate compared to other denoising algorithms, while retaining significantly more sequence information.
172 pient plasticity and elastoplastic behavior, while retaining similar levels of hardness; and nanoinde
173 tests, exhibiting improved statistical power while retaining similar, and reliable type I errors.
174 chloride simultaneously in the same lysosome while retaining single-lysosome information in live cell
175 ded confirmation and multiple pharmacophores while retaining solubility and oral bioavailability, and
176 t to the Paneth or enteroendocrine lineages, while retaining some stem cell activity.
177  enhances the sensitivity of TCR recognition while retaining specificity.
178 substantially reduced the number of features while retaining spiked QC compounds; however, a combinat
179 ve inference could potentially improve power while retaining statistical guarantees, especially those
180 errogate increasingly specific subphenotypes while retaining statistical power to detect genetic asso
181 the formation of robust endothelial networks while retaining statistically identical electrophysiolog
182 ability to bind an unknown cellular receptor while retaining substantial sialidase activity.
183 membrane integration via the Sec translocon, while retaining sufficient chemical and structural detai
184 tures and how these structures remain stable while retaining sufficient dynamics for functionality is
185 ion approach; however, balancing attenuation while retaining sufficient immunogenicity and efficacy h
186  from a sample solution in approximately 1 s while retaining sufficiently high concentration of a rel
187 f the 5'-phosphate from the phosphate pocket while retaining the 3' overhang in the 3' pocket.
188 d for more than 3 days and in a cost savings while retaining the ability of the clinician to obtain t
189 iant, CXCR4(QTY29), became more hydrophilic, while retaining the ability to bind its ligand CXCL12.
190 rmation of an insulating polydopamine layer, while retaining the ability to detect DA.
191                 To decrease such variability while retaining the ability to distinguish and enumerate
192 le guests with micromolar binding affinities while retaining the ability to effect turnover and catal
193  multiple antibiotic resistance determinants while retaining the ability to efficiently transmit and
194  mouse T cells, B cells and dendritic cells, while retaining the ability to enhance naive T-cell diff
195      To decrease variability between animals while retaining the ability to enumerate transmitted/fou
196 ormation transmission in a given environment while retaining the ability to quickly adapt to a new en
197     Tools that allow for in vivo EV labeling while retaining the ability to resolve cellular sources
198 , which increases the efficiency of sampling while retaining the accuracy of docking results.
199 able to overcome some of these disadvantages while retaining the advantages of both the systems.
200 tive power compared to a gene-level analysis while retaining the advantages of interpretability, robu
201 -squares (MCR-ALS), to circumvent this issue while retaining the advantages of multivariate analysis.
202 er than that of the ten competing statistics while retaining the appropriate type 1 errors.
203 depolymerization and deoxygenation of lignin while retaining the aromatic functionality are attractiv
204 ever, simulating realistically sized systems while retaining the atomistic description remains comput
205  those of silicon-based waveguide modulators while retaining the benefit of further device miniaturiz
206 ow ERAP1 can select peptides based on length while retaining the broad sequence-specificity necessary
207 applications requiring high-quality focusing while retaining the broadband/ultrashort characteristics
208 , low dissociation rate and reduced toxicity while retaining the capability of conjugating Ts1 with m
209 -positive DCs with aberrant immune functions while retaining the capability of proinflammatory cytoki
210 osensor to adhere onto the plasmonic surface while retaining the capability to undergo large structur
211 karyocyte maturation or platelet activation, while retaining the capacity for cross-correction in pat
212 g to 200 degrees C leads to a cycloreversion while retaining the COF crystallinity.
213 n in nuclear and multi-generational families while retaining the computational efficiency.
214 the complete (i.e. per-fragment) likelihood, while retaining the computational efficiently of the com
215  under challenging environmental conditions, while retaining the conformational flexibility necessary
216 urements based on the above X-ray techniques while retaining the coordinate system.
217 ajor histocompatibility complex restriction, while retaining the desirable antitumor properties of a
218  technique to selectively remove free PARP-1 while retaining the DNA-bound PARP-1, we demonstrate a d
219 ese engineered dimers do not expose the FLE, while retaining the EDE exposure.
220 tantly evolves to escape the immune response while retaining the essential elements needed to mediate
221 t could be used in further functionalization while retaining the excellent photophysical properties o
222 zation of dihydroxyspiropyran as a comonomer while retaining the excellent thermomechanical propertie
223 losed-loop control in biological experiments while retaining the flexibility needed for experimental
224 p classical mechanisms throughout the brain, while retaining the flexibility to investigate new mecha
225 or hetero-bivalent binding to the Env trimer while retaining the functional properties of the IgG1-Fc
226 e bonds to facilitate large-scale synthesis, while retaining the functionality of disulfide-bonded pe
227 tors to evade immune recognition by the host while retaining the immunomodulatory potential of their
228 o IgG4 equivalent to those of standard IgG1, while retaining the inability to trigger ADCC and CDC.
229 T), bimatoprost 0.01 % improved tolerability while retaining the intraocular pressure (IOP)-lowering
230 at of Barreto Lemos et al.'s quantum system, while retaining the latter's ability to image with undet
231 l ROS suppression should minimize the former while retaining the latter, which we achieved by express
232 ic simulation by several orders of magnitude while retaining the level of QM accuracy in describing t
233 gies, as the laf-net can fold into a 2D form while retaining the local geometry around each vertex.
234 lso, BLESS 2 showed at least 11% higher gain while retaining the memory efficiency of the previous ve
235  possess generalized prediction capabilities while retaining the model interpretability.
236 reate MOFs of increasing mechanical strength while retaining the MOP cavities.
237 aterial (black and white photographic film), while retaining the necessary precision to identify sulf
238 cantly enhanced from 10.3 to 11.7 mA cm(-2) (while retaining the open-circuit voltage and fill factor
239  multiple alternative transient interactions while retaining the overall binding and folding pathway.
240 ce binding and neutralization of Sudan virus while retaining the parental activity against EBOV and B
241 out asthma were lower for both RV-A and RV-C while retaining the pattern of gene expression and upstr
242  of these gene loci lose repressive H3K27me3 while retaining the permissive H3K4me3 modification.
243 reduce the risk for autoantigen presentation while retaining the phagocytic ability of homeostatic my
244 y, ghost cell production and membrane damage while retaining the pole localization.
245 emical properties of the designed inhibitors while retaining the potency for neural nitric oxide synt
246 a GO layer, which acted as the bio-receptor, while retaining the properties of the bottom layer of G,
247 most effective combination to remove albumin while retaining the protein of interest.
248 es the electron-density of the labeled cells while retaining the quality of the ultrastructure.
249 odel is proposed to reduce the resource cost while retaining the relevant ionic dynamics.
250 2 to evoke pneumonic plague in a mouse model while retaining the required immunogenicity needed for s
251  flexibility of the main His-beta-Ala chain, while retaining the rigidity conferred by the Zn-imidazo
252 rtesian-FRONSAC improves accelerated imaging while retaining the robustness and flexibility critical
253 nctionally demethylate expressed gene bodies while retaining the role of MeCP2 in chromatin organizat
254 thenticated, authorized and encrypted manner while retaining the same characteristics of standard Bit
255  RNA (let-7 microRNA family members) targets while retaining the same signal generation region.
256 antly improves the response time (~20 times) while retaining the stability and repeatability in addit
257  the K(+) ion sites partially by Li(+) ions, while retaining the structural integrity and accessible
258 ely protect the magnetic core from corrosion while retaining the superior contrast effect for MRI in
259 devoid of key chromatin interaction domains, while retaining the SWI/SNF-like helicase region.
260 o as FLASH tends to spare the normal tissues while retaining the therapeutic effect on tumor.
261 llular ligand-binding domain of the receptor while retaining the transmembrane and tyrosine kinase do
262 ior to elephant ivory and selected plastics, while retaining the visual appeal of a naturally occurri
263 dispersed as small ion clusters in a matrix, while retaining their ability to be processed in solutio
264 rance by foregoing germinal center responses while retaining their ability to function as antigen-pre
265 ng capability of traditional acoustic lenses while retaining their advantages in terms of 3-D underwa
266 from pluripotency towards primitive endoderm while retaining their capacity to re-enter self-renewal(
267          Irrespective of the digestion time, while retaining their capsid structural integrity, B1(V)
268  twisted and folded to multiple deformations while retaining their electrochemical performance.
269  adenocarcinomas undergo collective invasion while retaining their epithelial glandular architecture
270       Those neurons adapt to frequent sounds while retaining their excitability to rare sounds.
271  provides control over cellular permeability while retaining their favorable spectroscopic and photor
272 rally pattern protein release from hydrogels while retaining their full activity.
273 rates that can resist mechanical deformation while retaining their function of the bioreceptors and a
274 ogy may involve a significant size reduction while retaining their functional capabilities.
275 rejuvenation can be achieved in bulk samples while retaining their glassy structure.
276 ngs or neutral molecules larger than 3.4 nm, while retaining their high permeances to organic solvent
277 nvolved--qubits--communicate to other qubits while retaining their identity.
278 tterances by reversing the order of phonemes while retaining their identity.
279                                              While retaining their mechanical properties and remainin
280 nd macrophages release specific metabolites, while retaining their membrane integrity.
281 ited enhanced synthesis of HSC niche factors while retaining their mesenchymal differentiation capaci
282 capturing membrane proteins on chip surfaces while retaining their native conformation.
283 at reduce their negative psychological costs while retaining their positive societal benefits.
284 ition of thrombin and APC for both variants, while retaining their properties as contact system inhib
285 r to reduce the overall weight of structures while retaining their required strength.
286 lpha) and immunomodulatory (IL-10) cytokines while retaining their suppressive capacity.
287 nize into organoids that self-renew in vitro while retaining their tissue-of-origin commitment, genet
288 als that reduce their environmental toxicity while retaining their useful antibacterial properties ca
289 s using magnetic ionic liquid (MIL) solvents while retaining their viability.
290 hydrogen bond donor and acceptor groups, all while retaining their Watson-Crick geometries.
291 t of molecules associated with axonal damage while retaining transcription factors modulating neuropr
292 evice, and (iii) single-photon transmission, while retaining transverse structure, over 400 m of few-
293 ulation of constitutive proteasome subunits, while retaining unaltered immunoproteasome subunit expre
294  they are intrinsically thermally insulating while retaining useful properties of perfect crystals.
295 aches to the rational attenuation of VSIV NV while retaining vector immunogenicity and have led to id
296 ty compared to the gold-standard (N-MePhe)4, while retaining very high transport values.
297  is defined by their ability to secrete IL-1 while retaining viability, yet it is unclear how IL-1 ca
298 rtially recreate a complex antibody epitope, while retaining virus viability.
299 lacks the phylogenetically conserved stem P1 while retaining wild-type activity.
300 s subtilis that allows tRNA(Ile) mischarging while retaining wild-type Ile-tRNA(Ile) synthesis activi

 
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