ライフサイエンスコーパス: whole

1 declining performance of the ejaculate as a whole.

2 work that considers a set of parameters as a whole.

3 itive to the layered magnetic structure as a whole.

4 tation pathway of the catalyst particle as a whole.

5 prove the survival of the LT population as a whole.

6 mechanical load acting on the MT array as a whole.

7 impacts invasion of the metapopulation as a whole.

8 eeper understanding of ADP-ribosylation as a whole.

9 vidual roots as well as the root system as a whole adapt to the pattern of water availability to maxi

10 Three new studies use a whole adult brain electron microscopy volume to reveal n

11 ovement of molecules, organelles, cells, and whole animals.

12 Whole apple (WA) consumption decreased serum total (WA:

13 We found that a whole-arm model, unlike classic models, successfully pre

14 presence of metaphosphates, reported here in whole bacterial cells for the first time, opens the path

15 Whole blood (WB) and platelet-rich plasma (PRP) were per

16 Whole blood concentrations of 13.5 umol/L (95% credible

17 gregometry), conventional coagulation tests, whole blood counts, and platelet flow cytometry were per

18 first epigenome-wide methylation analysis of whole blood DNA samples from a cohort of septic and nons

19 The whole blood ELISpot assay offers a significant advance i

20 paration-free point-of-care (POC) device for whole blood glucose colorimetric detection.

21 Whole blood recipients (2016-2019) were compared to a pr

22 Whole blood samples from patients treated for symptomati

23 then calculating hematocrit (Hct) values of whole blood samples with nominal content of 28%, 35%, 40

24 ive detection in spiked plasma as well as in whole blood samples.

25 nsitive detection of protein biomarkers from whole blood samples.

26 sources (venous vs capillary) and matrices (whole blood vs DBS).

27 fter isovolumic haemodilution, where ~20% of whole blood was removed and replaced with 5% human serum

28 (sepsis-2 definition), BC and PCR/ESI-MS on whole blood were positive in 14.6% and 25.6% of cases, r

29 ntrations in the gold standard (i.e., venous whole blood) and that DBS is a suitable tool for assessi

30 assess metabolite-corrected radioactivity in whole blood, plasma, and urine.

31 ble isotope (delta(13) C) analysis of thrush whole blood, provides favourable pre-migratory condition

32 in vivo half-life and suboptimal potency in whole blood.

33 fluids, including urine, saliva, serum, and whole blood.

34 Whole-blood dihydroceramides and ceramides were decrease

35 vation by both species, we performed ex vivo whole-blood infection assays and confrontation assays wi

36 Fingerstick whole-blood samples were collected from participants in

37 concerns, and significantly improved LS and whole body BMD compared to participants on vitamin D/cal

38 Similar improvements were seen for whole body BMD.

39 rrow adipocyte also has an endocrine role in whole body homeostasis through its varied secretome that

40 Patients received 2 whole-body (18)F-DCFPyL PET/CT scans (median dose, 317 M

41 to localize and classify uptake patterns of whole-body (18)F-FDG PET/CT images in patients with lung

42 rgan (eg, contractility and metabolism), and whole-body (eg, physical activity and appetite) levels.

43 Results: Whole-body activity was reduced on average by 66.7% (ran

44 Whole-body and neuronal-specific downregulation of enzym

45 F compared with an energy-matched control on whole-body and skeletal muscle insulin and anabolic sens

46 oth inflammation and malignancy and offers a whole-body assessment.

47 the regional trauma centre and subjected to whole-body computed tomography (WBCT) due to injuries.

48 Conclusion Whole-body diffusion-weighted MRI showed significant agr

49 (CaMKK2) is a key regulator of cellular and whole-body energy metabolism.

50 Whole-body exposures were carried out for 3 h/d, 7 d/wee

51 ly, weightlifting training profound improved whole-body glucose clearance and skeletal muscle insulin

52 ulin action in adipose tissue is crucial for whole-body glucose homeostasis, with insulin resistance

53 An automated whole-body high-uptake segmentation algorithm identified

54 onal SPECT/CT images were obtained after the whole-body images at 2 and 24 h if there was relevant up

55 Planar whole-body imaging was performed at 2 and 24 h after inj

56 In CON, the training intervention increased whole-body insulin action by 26% and insulin-stimulated

57 When compared with CON:CR, eTRF improved whole-body insulin sensitivity [between-group difference

58 were performed using tissue sections from a whole-body mouse pup.

59 ptors to investigate their role in affective whole-body movement perception.

60 There was only slight agreement between whole-body MRI and CT (Cohen kappa, 0.15).

61 dipose tissue segmentation is feasible in 3D whole-body MRI datasets and is generalizable to differen

62 cal evidence of liver metastases at baseline whole-body MRI, two participants were excluded because t

63 er, renal cell cancer, or leukemia underwent whole-body PET/CT imaging 90 min after injection of (18)

64 Human image data acquired on a conventional whole-body PET/CT system with a typical clinical protoco

65 Whole-body planar imaging was acquired at 1, 2, 3, 6, an

66 eofluoroscopy, ultrasonic vocalizations, and whole-body plethysmography were used to assess VF motion

67 a protein-rich meal on, protein absorption, whole-body protein turnover, and splanchnic amino acid m

68 Whole-body retention half-time averaged 198 +/- 75 h.

69 we exposed 6-month-old C57BL/6J male mice to whole-body space radiation and subsequently assessed the

70 iratory and cardiac motion is visible, and a whole-body survey.

71 ment over untreated controls and resulted in whole-body toxicity.

72 Yet, the implications of PSMA PET-derived whole-body tumor volume for overall survival are poorly

73 cells interact with synapses throughout the whole brain and are recognized as regulatory elements of

74 from the Allen Brain Institute, we generated whole brain and regional signatures of AMPAR subunit gen

75 different brain structures as well as in the whole brain of all mammalian species examined.

76 specific gene expression pattern across the whole brain, finding a distinct anterioventral-posteriod

77 generally, the pharmacological modulation of whole-brain activity.

78 Whole-brain analyses of cortical thickness were conducte

79 esian spatial generalized linear mixed model whole-brain analysis identified left V3/V3A as the area

80 poral cortex, and insula (Z > 2.3; p < 0.05; whole-brain corrected).

81 ght multivariate pattern classification, and whole-brain decoding with L1 or L2 regularization-each h

82 Leveraging a whole-brain electron microscopy volume, we studied the a

83 a particular, temporally dynamic pattern of whole-brain functional connectivity, and this encoding i

84 tivity magnetic resonance imaging to examine whole-brain functional networks in children and adults w

85 upon adaptive changes in the organization of whole-brain functional networks.

86 In worms, this reporter enables whole-brain imaging with faster kinetics and brighter fl

87 Remarkable progress has come from whole-brain models linking anatomy and function.

88 Results: Each radioligand gave high early whole-brain uptake of radioactivity, followed by a brief

89 Whole-brain voxelwise analysis revealed that activity re

90 ion cell plus inner plexiform layer (GCIPL), whole-brain, gray matter and thalamic volumes in patient

91 findings that a once-weekly 5-fr schedule of whole-breast radiotherapy can be identified that appears

92 Whole cell CRAC current is Ca(2+) -selective.

93 the specific turnover numbers of individual whole-cell biocatalysts.

94 We used a simple whole-cell coarse-grained model of cell physiology that

95 ion specifically in synapses, and not at the whole-cell level.

96 A multifaceted approach, including in vitro whole-cell patch recordings, in vivo single-unit recordi

97 By combining whole-cell patch-clamp and 2-photon laser scanning micro

98 her mutations in HEK293T cells and performed whole-cell patch-clamp electrophysiology.

99 We performed whole-cell patch-clamp recordings of medium spiny neuron

100 Whole-cell patch-clamp recordings reveal that detection

101 Whole-cell patch-clamp recordings were obtained from Pur

102 obustly blocks anesthetic TREK-1 currents in whole-cell patch-clamp recordings.

103 Whole-cell recordings in basolateral amygdala (BLA) slic

104 ions were discovered [15], we used quadruple whole-cell recordings to screen connectivity within the

105 Using whole-cell recordings, we found that the alpha3beta4* nA

106 ytotoxicity and hemolysis assays, as well as whole-cell uptake and development of resistance studies.

107 Here, we compared the lipid composition of whole cells of the pigmented E. gracilis strain Z and tw

108 l view of ultrastructural variability across whole cells.

109 ermining the complete 3D organization of the whole chromatin polymer is an inverse problem.

110 ificantly lower for segmental as compared to whole-chromosome aneuploidies (70.8% versus 97.18%, resp

111 Contrary to the prevalent meiotic origin of whole-chromosome aneuploidies, we show that sub-chromoso

112 the first telomere-to-telomere assemblies of whole chromosomes.

113 4 and CYP1A2, matching effects observed with whole clementine juice.

114 mum angle of resolution visual acuity of the whole cohort was 0.2 (0.5).

115 The prevalence of lean NAFLD patients in the whole cohort was 13.9%.

116 Assessing the whole cohort, 0.39% of patients (10/2572) had 12 TET2 mu

117 The whole colon was then removed and stained to visualize si

118 providing growth/survival advantages for the whole community.

119 btained from the algorithm, by analyzing the whole CT scan, correlated with the diffusion lung capaci

120 ssibility of predicting total fat content in whole dried cocoa beans at a single bean level using hyp

121 This is one of the first whole-ecosystem experiments to involve replicated metage

122 yet we know little about how warming affects whole ecosystems.

123 must correctly reflect the influence of the whole environment.

124 Here we perform whole exome sequencing and gene expression analysis of m

125 ber status of genes and genomic regions from whole exome sequencing data.

126 We performed whole exome sequencing on this cohort and applied 2 hypo

127 Whole exome sequencing was performed on all patients.

128 number alterations, mutational signatures in whole exome, and tumor mutational burden in predicting N

129 als using targeted (n = 1914 microbiopsies), whole-exome (n = 655), and whole-genome (n = 88) sequenc

130 We performed whole-exome and shallow whole-genome sequencing to ident

131 pathogenesis, here we analyze whole-genome, whole-exome and/or transcriptome data from 702 neuroblas

132 addressing the use of targeted panels versus whole-exome sequencing (WES).

133 By studying whole-exome sequencing and whole-genome bisulfite sequen

134 Whole-exome sequencing at multiple time points reveal ac

135 Retrospective whole-exome sequencing confirmed a homozygous splice-sit

136 sequent genotyping and analysis of available whole-exome sequencing data of additional case/control s

137 Whole-exome sequencing identified a heterozygous nonsyno

138 Whole-exome sequencing identified hemi- and heterozygous

139 Whole-exome sequencing identified UV-signature mutations

140 We performed whole-exome sequencing in 222 OCD parent-child trios (18

141 To address this gap, we performed whole-exome sequencing in 58 men with unexplained meioti

142 Whole-exome sequencing of 159 prospectively resected pit

143 andidate genetic variants were identified by whole-exome sequencing of 2 patients with familial IMD.

144 stics of idiopathic NOA and SO, we performed whole-exome sequencing of 314 unrelated patients of Chin

145 Using whole-exome sequencing of samples from 20 PCa families,

146 By whole-exome sequencing, we identified rare homozygous ge

147 Here, by whole-exome/genome sequencing we identify heterozygous,

148 to study legacy effects, from tree rings to whole forests.

149 r intakes of cereal fiber, coffee, nuts, and whole fruits; and a higher ratio of polyunsaturated to s

150 nor changes in gene expression compared with whole-gene deletions for these COMPASS members.

151 ances of two commercially available kits for Whole Genome Amplification (WGA), PicoPLEX and RepliG we

152 Whole genome and exome sequencing followed by Sanger con

153 By sequencing the whole genome of MERS-CoV from persistently infected bat

154 Whole genome sequence (WGS) data could transform our abi

155 ived from comprehensive sets of AMR genes or whole genome sequences and may not be suitable for use w

156 tic resistance genes from various formats of whole genome sequences based on the CARD or ResFinder da

157 The availability of whole genome sequences was expected to supply essentiall

158 ility, Multilocus Sequence Typing (MLST) and Whole Genome Sequencing (WGS) analysis.

159 Whole genome sequencing (WGS), on the other hand, allows

160 rsity and characterization were performed by whole genome sequencing (WGS).

161 st-line approach, followed by a more refined whole genome sequencing analysis.

162 Whole genome sequencing data did not identify a strain g

163 We performed whole genome sequencing for two American minks with Moyl

164 Whole genome sequencing in multiplex families, proband-p

165 noma occurring on palms, soles or nail beds, whole genome sequencing of 87 tumors with matching trans

166 SWGA enables the successful whole genome sequencing of samples with low parasite den

167 Whole genome sequencing of select transformants demonstr

168 MIC, pDST and whole genome sequencing of the pncA, rpsA and panD genes

169 Whole genome sequencing revealed differences in putative

170 Whole genome sequencing was performed on 20 matched bloo

171 Whole genome sequencing was used to uncover a frame-shif

172 By parent-offspring whole genome sequencing, we estimate a mutation rate (3.

173 Using whole genome sequencing, we identified a heterozygous fr

174 sualize not only single genomic loci but the whole genome simultaneously.

175 ventricular cardiomyocytes and interrogated whole genome transcriptional responses.

176 ains and losses at the same areas across the whole genome.

177 4 microbiopsies), whole-exome (n = 655), and whole-genome (n = 88) sequencing.

178 sing 84,729,690 somatic mutations from 4,645 whole-genome and 19,184 exome sequences that encompass m

179 This is particularly challenging when large whole-genome and metagenome databases are involved.

180 By studying whole-exome sequencing and whole-genome bisulfite sequencing of cell free DNA (cfDN

181 LITAF-deficient cells, a second, subsequent whole-genome CRISPR-Cas9 screen identified the LITAF-lik

182 the ever-increasing quality and quantity of whole-genome data, evolutionary insight into origins of

183 Whole-genome deep sequencing-based analysis has revealed

184 We also provide evidence for a whole-genome duplication event in the lineage leading to

185 nalysis with yeast paralogs derived from the whole-genome duplication event.

186 Finally, we confirmed an ancient whole-genome duplication that took place in a common anc

187 research is the first study to characterize whole-genome expression in fibroblast cells obtained fro

188 eassuring de facto positive controls for our whole-genome gene expression discovery approach.

189 nd model organisms including body images and whole-genome gene expression profiles.

190 lity of the new implementation by building a whole-genome index of the 5008 haplotypes of the 1000 Ge

191 ntire protocol from tissue reception through whole-genome library generation can be accomplished in a

192 We performed a high-throughput whole-genome RNAi screen to identify novel inhibitors of

193 We analyzed whole-genome sequence data from 165 primary membranoprol

194 the same wards within 7 days were chosen for whole-genome sequencing (WGS) and a phylogenetic analysi

195 the genomic landscape of myeloma using deep whole-genome sequencing (WGS) and develop a model that i

196 Whole-genome sequencing (WGS) can support surveillance b

197 Here we perform whole-genome sequencing (WGS) of 103 UM from all sites o

198 ver, new sequencing approaches, particularly whole-genome sequencing (WGS), have dramatically changed

199 ased caution to address systematic biases in whole-genome sequencing and alignment.

200 However, the increasing application of whole-genome sequencing as a diagnostic tool is leading

201 Cancer Genome Atlas (TCGA), which aggregated whole-genome sequencing data from 2,658 cancers across 3

202 Using matched whole-genome sequencing data, we associated several cate

203 As access to whole-genome sequencing has grown, greater amounts of mo

204 Using whole-genome sequencing of zebrafish mutants isolated in

205 VAPOR retrieved references for 257 real whole-genome sequencing samples with a mean of >99.8% id

206 We performed whole-exome and shallow whole-genome sequencing to identify genes and pathways p

207 ARO colonization on NF admission, we applied whole-genome sequencing to track the spread of 4 ARO spe

208 Methods: Within a prospective multicenter whole-genome sequencing trial (NCT01855477), 69 mPC pati

209 g genomic data, particularly when annotating whole-genome sequencing variants against a huge database

210 landers with genetic information (imputed or whole-genome sequencing).

211 crobial resistance determination, such as by whole-genome sequencing, are required.

212 using a combination of short- and long-read whole-genome sequencing, we found no significant associa

213 ated sources in NYS were characterized using whole-genome sequencing.

214 hetic pathway genes are impacted by a recent whole-genome triplication event.

215 Employing whole-genome, exome, transcriptome, and methylation sequ

216 neuroblastoma pathogenesis, here we analyze whole-genome, whole-exome and/or transcriptome data from

217 Here we produced and analysed whole-genome, whole-transcriptome and DNA methylation da

218 Established methods for whole-genome-sequencing (WGS) technology allow for the d

219 Thus, using a cohort-based whole-genome-sequencing approach in the diagnosis of PID

220 T)], TERT mRNA expression by RNA-sequencing, whole-genome/exome sequencing, and clinical covariates i

221 Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Ca

222 m 1,188 donors of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Ca

223 Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium(2) of the International

224 nome dataset from the Pan-Cancer Analysis of Whole Genomes (PCAWG) project in a time-efficient and un

225 le myeloma evolution in a large cohort of 89 whole genomes and 973 exomes.

226 he genetic basis for phenotypic evolution as whole genomes continue to populate the tree of life.

227 Here, we sequenced the whole genomes of 24 individual pigs representing 22 bree

228 of pairwise nucleotide differences among the whole genomes was found to be 788.690 with a diversity i

229 scribed spacer regions, and for 4 others the whole genomes.

230 r the determination of the two mycotoxins in whole grain samples (wheat and maize).

231 Higher intakes of whole grains and dietary fiber have been associated with

232 When considered jointly, highest intake of whole grains with the highest intake of dietary fiber sh

233 However, a diet based on vegetables, fruits, whole grains, and legumes, supplemented with vitamin B-1

234 greater consumption of healthy plant foods (whole grains, fruits, vegetables, nuts, legumes, tea and

235 33) > LT (4.10) > RT (3.90) whereas, Spanish whole green olive (SP2) showed more phenolics (20.72).

236 cy for %FFML to predict weight regain in the whole group (beta: 0.041; 95% CI: -0.001, 0.08; P = 0.05

237 The whole group of antipsychotic-naive patients had lower le

238 We performed whole gut transit, bead latency, and geometric center st

239 ells was predictive of progression along the whole IA-continuum.

240 the predominant compound in almond skin and whole kernel but it was not found in deskinned kernels.

241 high-resolution 3D model of molecular marked whole laryngeal cancer by optimizing the currently avail

242 reference genome, limiting the potential of whole metagenomics.

243 broad-band absorption/emission covering the whole mid-infrared wavelength(11-15).

244 branous, cytoplasmic and nuclear antigens in whole mouse organs and embryos, human biopsies, organoid

245 lance assessment: triads, subgroups, and the whole network.

246 r adults from two independent cohorts, using whole-night electroencephalography.

247 ts are aggregated to larger scales (e.g. the whole North Sea), to total catches rather than individua

248 al conditions (temperature, roasting, use of whole nuts, screw speed and nozzle diameter), and compar

249 or elucidating developmental lineages at the whole organism level.

250 -organelle, single-cell, tissue section, and whole organism levels.

251 in antimalarial drug discovery, against the whole organism.

252 mic information guaranties reproduction of a whole organism.

253 e/loxP and Tet-On/Tet-Off systems can affect whole-organism physiology and function due to off-target

254 reatic islet, consisting of 1-2% mass of the whole pancreas, has long been believed to be regulated i

255 The scaling exponents of whole-plant metabolic rate vs body size numerically conv

256 ral networks (CNNs) have been applied to the whole PPG signals as input.

257 cral spine to hinder the dorsal slope of the whole presacral series caused by the wedged sacrum.

258 al emotional behaviors by "calming down" the whole PrL.

259 The whole process followed the PRISMA statement.

260 pure water droplets is too small to host the whole process.

261 After prostatectomy, the fresh whole prostate specimens were imaged in patient-specific

262 work is applied to extract features from the whole protein sequence.

263 We expanded our analysis across whole proteomes and found that other characterized immun

264 The dynamic range covers the whole range of clinically relevant concentrations of the

265 emia and neonatal AA was observed across the whole range of maternal mid-gestation glucose concentrat

266 werful approach to study Mtb metabolism as a whole, rather than just individual enzymatic components,

267 f PCS and PPCS crudes rates over time in the whole region, accompained by a progressive enhancement o

268 Although the whole representative data characterizing the immune and

269 ehensive transcript profiles of Brachypodium whole-root system at four developmental stages.

270 outcomes, while corn and soybean yields and whole-rotation economic returns improved significantly u

271 Mean number of primary rugae in the whole sample was 4.35 (SD, 0.98) on the right and 4.33 (

272 tegies for adding 3% black quinoa (either as whole seeds or as a fiber-rich fraction of quinoa from i

273 We found that whole semen significantly reduces the potency of antibod

274 Whole-slide histology images contain information that is

275 ative to age-matched controls, the levels of whole SN triglycerides were correlated with inflammation

276 in patients with cirrhosis encompassing the whole spectrum of disease (compensated, acutely decompen

277 Clinical trials using whole-sporozoite-based vaccination approaches such as th

278 er protein that binds to SMCR8 such that the whole structure resembles an eye slip hook.

279 ays a vital role in the stabilization of the whole structure.

280 The whole surface of the microspot BDD electrode was found a

281 and analysis tools, we show that, within the whole system (beyond the droplet stage), macroscopic int

282 As a whole, this study presents a new computational framework

283 cilitating their specific isolation from the whole tissue as live cells.

284 Despite whole tissue biopsy studies that have advanced the mecha

285 rts lens function, we have developed a novel whole tissue imaging system using conventional confocal

286 This study examined tubulin acetylation in whole-tissue homogenate, plasma membrane, and lipid-raft

287 CD38 mediated the eNAD metabolism in whole tissues, but CD38 did not appear to be functionall

288 etation of changes in the transcriptome as a whole to predict disease progression.

289 dentify a broadly useful gene panel based on whole transcriptome technology.

290 Here we produced and analysed whole-genome, whole-transcriptome and DNA methylation data for 208 pai

291 with human stem cells is investigated using whole-transcriptome sequencing (RNA-seq).

292 Whole-transcriptome sequencing by RNA sequencing (RNA-Se

293 ar system are occluded for the first and the whole tumour vasculature is destroyed for the latter.

294 thereby affecting ecosystem processes of the whole tundra region.

295 re present in all tested recombinant HAs and whole viruses and can be specifically targeted for unive

296 Whole volume of the abdominal and lumbar paraspinal musc

297 40-fold faster than curve fitting, obtaining whole volume perfusion maps in just over 10 s.

298 e dendrite integrates excitatory inputs as a whole, we combined anatomic quantifications of the affer

299 (less than 0.2%) in the food matrix such as whole wheat flour.

300 deaths related to population ageing for the whole world, as well as in 55.3% (84/152) of countries f