ライフサイエンスコーパス: whole-genome sequence

1 found that 41 carried mcr-9 (validated using whole genome sequencing).

2 landers with genetic information (imputed or whole-genome sequencing).

3 c coverage across the 670 cM/352.9 Mb cherry whole genome sequence.

4 n affected cat from the original colony, was whole genome sequenced.

5 nomic links using Mycobacterium tuberculosis whole-genome sequences.

6 , whole exome sequencing, and more recently, whole genome sequencing.

7 s, have not proved tractable with short-read whole genome sequencing.

8 he origin and evolution of this system using whole genome sequencing.

9 ncluding multilocus typing of five genes and whole-genome sequencing.

10 genetic test with whole-exome sequencing or whole-genome sequencing.

11 e readily selected, from single mutations to whole-genome sequencing.

12 sequencing panels as well as whole-exome and whole-genome sequencing.

13 lates were previously categorized via PCR or whole-genome sequencing.

14 have been analysed by both transcriptome and whole-genome sequencing.

15 etation of structural variants in the era of whole-genome sequencing.

16 rulence and antibiotic resistance assays and whole-genome sequencing.

17 osely related to the main outbreak strain by whole-genome sequencing.

18 variant by genome-wide association study and whole-genome sequencing.

19 ated sources in NYS were characterized using whole-genome sequencing.

20 Cultured isolates underwent whole-genome sequencing.

21 g with K1 open reading frame Sanger and KSHV whole-genome sequencing.

22 is evolutionary process, we interrogated, by whole genome sequencing, 25 samples collected at autopsy

23 Whole genome sequencing (30X) and digital droplet PCR (d

24 We whole-genome sequenced 446 colonic crypts from 46 IBD pa

25 The comparison of whole-genome sequences across 10 additional Formica spec

26 Whole genome sequencing alerted us to the existence of g

27 lerated short-read aligner, can compute WGS (whole-genome sequencing) alignments ten times faster tha

28 However, the wide adoption of whole-genome sequencing also poses new challenges for pu

29 Here we performed whole-genome sequencing analyses of 426 individuals-comp

30 Whole genome sequence analysis was performed on a subset

31 st-line approach, followed by a more refined whole genome sequencing analysis.

32 The combination of near to real-time whole-genome sequence analysis and epidemiology resulted

33 Whole-genome sequence analysis demonstrated the Houston

34 Here, through whole-genome sequence analysis of 172 indigenous African

35 The growth of ESBL-E was quantified and a whole-genome sequence analysis was performed.

36 ol on microbial strain safety assessment via whole-genome sequence analysis.

37 bility in MMR-deficient gliomas, single-cell whole-genome sequencing analysis of post-treatment hyper

38 region on canine chromosome 33, followed by whole-genome sequencing analysis that revealed a long in

39 cal Genome Reference Bank (MGRB), comprising whole genome sequence and phenotype of 2570 elderly Aust

40 The increasing availability of cancer whole genome sequences and functional genomics data from

41 ived from comprehensive sets of AMR genes or whole genome sequences and may not be suitable for use w

42 y ageing, but there is no public resource of whole genome sequences and phenotype data from healthy e

43 Whole genome sequencing and cytogenetics of experimental

44 ights into its biosynthesis were provided by whole genome sequencing and gene deletion studies, while

45 able SV discovery in non-model species using whole genome sequencing and report 15,483 high-confidenc

46 We sought to comprehensively investigate whole-genome sequence and RNA sequence from human bronch

47 ith different K1 open reading frame and KSHV whole-genome sequences and a different epidemiological c

48 ased caution to address systematic biases in whole-genome sequencing and alignment.

49 lts were confirmed using pathogen isolation, whole-genome sequencing and antibiotic susceptibility te

50 estion, fluorescence-activated cell sorting, whole-genome sequencing and data analysis.

51 lysis provides results on the integration of whole-genome sequencing and deep phenotyping for clinica

52 nd rarer kidney cancer subtypes, integrating whole-genome sequencing and DNA methylation data.

53 Whole-genome sequencing and phylogenetic analysis of 388

54 Whole-genome sequencing and SNP-level analysis was condu

55 The polyclonal nature of strains revealed by whole-genome sequencing and the apparent lack of epidemi

56 Data from whole-genome sequencing and transcriptome studies were t

57 Through a combination of whole-genome sequencing and transcriptomics, we showed t

58 Using whole-genome sequencing and tribal fishery sampling of C

59 itulates mutational signatures identified by whole genome sequencing, and will ultimately allow the s

60 th genomic data from whole exome sequencing, whole genome sequencing, and/or array-based imputation.

61 54 y [range 20 to 89+]; 70.6% European) had whole-genome sequencing, and were deeply phenotyped usin

62 Thus, using a cohort-based whole-genome-sequencing approach in the diagnosis of PID

63 Whole-exome and whole-genome sequencing are becoming financially feasibl

64 crobial resistance determination, such as by whole-genome sequencing, are required.

65 However, the increasing application of whole-genome sequencing as a diagnostic tool is leading

66 t suspected, adopting whole-exome sequencing/whole-genome sequencing as a first-line test should be c

67 tic resistance genes from various formats of whole genome sequences based on the CARD or ResFinder da

68 comprehensive descriptor of the organism, a whole-genome sequence-based ToL can be an empirically de

69 tions, and duplications were genotyped using whole-genome sequencing-based data.

70 ata to create the largest, to our knowledge, whole-genome-sequencing-based structural variant resourc

71 have been enabled by accurate comparisons of whole-genome sequences between parents and offspring.

72 into lineages and sublineages based on their whole-genome sequences, but little is known about the im

73 Whole-genome sequencing can be used to estimate subclona

74 Applying SigProfilerSimulator to 2144 whole-genome sequenced cancers reveals: (i) that most do

75 n testing for five lipid traits in two UK10K whole genome sequencing cohorts, hypothesizing that cis-

76 Whole-genome sequencing confirmed distinct species ident

77 Surveillance strategies based on whole genome sequencing could help with the early identi

78 Whole genome sequencing coupled with an outbreak-strain-

79 likely-gene-disrupting variants encoded from whole genome sequence data to ASD; however, this previou

80 We used the feline SNV array and whole genome sequence data to undertake a genome wide-as

81 expensive to obtain genotype data and indeed whole genome sequence data, the question then becomes to

82 read signals for potential SV breakpoints in whole genome sequencing data and proposes a probabilisti

83 Whole genome sequencing data did not identify a strain g

84 q and RNA-seq, and then integrate these with whole genome sequencing data from 232 OCs.

85 Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38

86 Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38

87 Whole genome sequencing data from cases and controls wer

88 The multi-tissue gene expression and whole genome sequencing data generated by the Genotype-T

89 ions will allow for better interpretation of whole genome sequencing data in the large number of pati

90 fill this gap, we extend TWAS to integrating whole genome sequencing data with transcriptomic data fo

91 Using the GTEx whole genome sequencing data, we identify 20,545 high-qu

92 o accurately assemble organelle genomes from whole genome sequencing data.

93 c health microbiology, the interpretation of whole-genome sequence data by nonspecialists becomes ess

94 Examining whole-genome sequence data describing a chronic case of

95 We analyzed whole-genome sequence data from 165 primary membranoprol

96 trophic lateral sclerosis (ALS) by analyzing whole-genome sequence data from 2,442 FTD/ALS patients,

97 in the rhesus macaque (Macaca mulatta) using whole-genome sequence data from 32 individuals in four l

98 Finally, we integrate this information with whole-genome sequence data from 375 individual mosquitoe

99 g of a rapid-flowering mutant was done using whole-genome sequence data from bulked DNA from a segreg

100 Applied to whole-genome sequence data from Plasmodium parasites, An

101 Genetic variants were examined using whole-genome sequencing data among survivors of African

102 Genomes (PCAWG) Consortium, which aggregated whole-genome sequencing data and RNA sequencing from a c

103 Short-read whole-genome sequencing data are often applied to large-

104 Utilizing high-coverage whole-genome sequencing data as part of the Trans-Omics

105 Our interrogation of the whole-genome sequencing data for 215 breast tumors catal

106 es and quality control measures for handling whole-genome sequencing data for mutational signature an

107 Using public whole-genome sequencing data from 2,606 samples from dif

108 Cancer Genome Atlas (TCGA), which aggregated whole-genome sequencing data from 2,658 cancers across 3

109 f Whole Genomes Consortium, which aggregated whole-genome sequencing data from 2,658 cancers across 3

110 Genomes (PCAWG) Consortium, which aggregated whole-genome sequencing data from 2658 cancers across 38

111 We analyze whole-genome sequencing data from 268 patients to catalo

112 We analyzed whole-genome sequencing data from 43 202 Icelanders.

113 We applied SBMClone to single-cell whole-genome sequencing data from two breast cancer pati

114 ural variant caller utilizing low-depth (8X) whole-genome sequencing data generated by Oxford Nanopor

115 hen using dense imputation from multi-ethnic whole-genome sequencing data in admixed Hispanics/Latino

116 a new theoretical framework that, applied to whole-genome sequencing data of healthy tissue and cance

117 feasibility of using Oxford Nanopore MinION whole-genome sequencing data of Mycobacterium tuberculos

118 Whole Genomes (PCAWG) Consortium, we dissect whole-genome sequencing data of over 2500 matched tumor-

119 high sequence and structural diversity from whole-genome sequencing data remains highly challenging.

120 836).Methods: We used admixture-mapping and whole-genome sequencing data to discover genomic regions

121 lassifiers have successfully been applied to whole-genome sequencing data to identify genetic determi

122 y in PAH we integrated deep phenotyping with whole-genome sequencing data using Bayesian statistics.

123 Here, we combine long- and short-read whole-genome sequencing data with recent assembly approa

124 Using matched whole-genome sequencing data, we associated several cate

125 and 60-80% of indels detected in human brain whole-genome sequencing data.

126 of structural variant (SV) breakpoints from whole-genome sequencing data.

127 otransposon insertions for both targeted and whole-genome sequencing data.

128 ross 2,658 tumors from 38 cancer types using whole-genome sequencing data.

129 We also applied our methodology to a TOPMed whole-genome sequencing dataset with 897 asthmatic trios

130 newly inferred D genes by analyzing diverse whole genome sequencing datasets and haplotyping heteroz

131 o test for genetic differences, we performed whole genome sequencing, deep mitochondrial DNA (mtDNA)

132 Unbiased whole genome sequencing demonstrates high specificity of

133 characteristics, and performed mycobacterial whole-genome sequencing, dormancy phenotyping and drug-s

134 he B10K ("Bird 10,000 Genomes") consortium's whole-genome sequencing effort, we have included 363 ann

135 It highlights the role of whole-genome sequencing, expanded phenotypic drug suscep

136 ts by RNA sequencing, followed by additional whole-genome sequencing experiments.

137 We performed whole genome sequencing for two American minks with Moyl

138 for the coral Acropora millepora We obtained whole-genome sequences for 237 phenotyped samples collec

139 A key goal of whole-genome sequencing for studies of human genetics is

140 r dysenteric diarrhea and endorse the use of whole-genome sequencing for sustained surveillance of NT

141 investigations with analysis of mumps virus whole genome sequences from 201 infected individuals, fo

142 These are the first HPV35 whole genome sequences from Zimbabwe, and these data fur

143 Here we analyse high-coverage whole-genome sequences from 97,691 participants of diver

144 (CAD) reference distribution was built using whole-genome sequencing from 1,522 Indian individuals, a

145 This study used imputed whole-genome sequencing from the Trans-Omics for Precisi

146 Whole-genome sequencing has enhanced surveillance and fa

147 As access to whole-genome sequencing has grown, greater amounts of mo

148 Short- and long-read whole-genome sequencing highlighted a duplication involv

149 While whole genome sequencing holds promise, it is not yet fea

150 ction and characterizing the viral load, RSV whole-genome sequencing, host immune response, and trans

151 onal strand asymmetry of indels across 2,575 whole genome sequenced human cancers.

152 Whole genome sequencing in multiplex families, proband-p

153 re we address these challenges by performing whole-genome sequencing in a large PID cohort of 1,318 p

154 Whole-genome sequencing in one affected dog and its obli

155 d MFRP and PRSS56 testing in 20 families and whole-genome sequencing in one family.

156 We also show that Hi-C can supplement whole-genome sequencing in structure variant detection b

157 e generated and analyzed, and how SARS-CoV-2 whole-genome sequencing, in combination with epidemiolog

158 ts and saline flushes were highly related by whole-genome sequencing, indicating a common source.

159 scan of the entire cohort, in parallel with whole-genome sequencing, methylation, and other 'omics a

160 Recent studies have uncovered whole genome sequence of SARS-CoV-2 (causing COVID-2019)

161 The whole genome sequences of two salt tolerant (Pokkali and

162 e analyzed 6.8 million variants derived from whole genome sequencing of 160 islet autoantibody positi

163 noma occurring on palms, soles or nail beds, whole genome sequencing of 87 tumors with matching trans

164 Here we have performed whole genome sequencing of consecutive M. tuberculosis i

165 Whole genome sequencing of paired isolates was used to i

166 SWGA enables the successful whole genome sequencing of samples with low parasite den

167 Whole genome sequencing of select transformants demonstr

168 AD, we performed a genetic screen from deep whole genome sequencing of the large NIMH family-based A

169 MIC, pDST and whole genome sequencing of the pncA, rpsA and panD genes

170 Since the whole-genome sequence of an organism is, at present, the

171 Application of DeepMILO on variants from whole-genome sequences of 1834 patients of twelve cancer

172 Our study of the whole-genome sequences of 53 organisms showed a positive

173 We present the first whole-genome sequences of B. pseudomallei isolates from

174 Here we analyse whole-genome sequences of males from native populations

175 However, experimentally determining the whole-genome sequences of many diverse organisms was pra

176 Whole-genome sequences of seven phage susceptible A. bau

177 Whole-genome sequences of substrains make RCCs possible

178 Through whole-genome sequencing of 13 melanoma metastases sample

179 hmania braziliensis species complex based on whole-genome sequencing of 67 isolates from 47 localitie

180 Therefore, whole-genome sequencing of 756 child-parent trios of Eur

181 Shallow whole-genome sequencing of 777 biopsies, sampled from 88

182 We conducted whole-genome sequencing of all 1,575 available GAS macro

183 Here we used whole-genome sequencing of clonal cell isolates that dev

184 Whole-genome sequencing of clonal organoids before and a

185 Since whole-genome sequencing of many crops has been achieved,

186 Here, Whole-Genome Sequencing of Mycobacterium bovis isolated

187 e used this workflow to perform targeted and whole-genome sequencing of small populations of cells (t

188 We performed whole-genome sequencing of the SKBR3 breast cancer cell

189 Whole-genome sequencing of uncultured eukaryotic genomes

190 dilution AST with seven antibiotics and for whole-genome sequencing of up to 5,000 isolates.

191 Using whole-genome sequencing of zebrafish mutants isolated in

192 We performed whole genome sequencing on isolates from early pediatric

193 We performed whole-genome sequencing on food and clinical isolates.

194 and it can be applied to large cohorts with whole-genome sequence or SNP array data.

195 egion of a genome, are readily obtained from whole-genome sequencing or microarrays.

196 However, working with whole genomes sequenced over several years in different

197 f this intervention in a model that compared whole-genome sequencing plus current practice versus cur

198 The large-scale availability of whole-genome sequencing profiles from bulk DNA sequencin

199 Whole-genome sequencing projects are increasingly popula

200 ly longer sequence reads, which when used in whole-genome sequencing projects have yielded better rep

201 imultaneous analyses of germline and somatic whole-genome sequences provide the opportunity to identi

202 Using 76 whole genome sequences representing 21 orders spanning m

203 al resistance (AMR), classic genotyping, and whole-genome sequencing results.

204 Whole genome sequencing revealed differences in putative

205 s and phylogenetic analyses of five-gene and whole-genome sequences revealed two groups, both of whic

206 Whole-genome sequencing reveals the absence of off-targe

207 Rapid whole genome sequencing (rWGS) of peripheral blood has b

208 was a randomized, controlled trial of rapid whole-genome sequencing (rWGS) or rapid whole-exome sequ

209 test this hypothesis through the analysis of whole genome sequences sampled from admixed Latin Americ

210 VAPOR retrieved references for 257 real whole-genome sequencing samples with a mean of >99.8% id

211 At present, based on whole genome sequencing, sequences and genes annotation

212 31 patients were examined by culture, qPCR, whole genome sequencing, serotyping, and reverse transcr

213 Large-scale whole-genome sequencing studies have enabled the analysi

214 We analyzed whole genome sequences to identify Piezo1 variants and t

215 ella Typhi isolates from India were found by whole genome sequencing to be closely related to the 201

216 Here, we used whole genome sequencing to characterise Pseudomonas aeru

217 Here we use C. elegans whole genome sequencing to systematically quantify the c

218 We used whole-genome sequences to compare genomes from periods b

219 In this study, we used whole-genome sequencing to analyze a large collection of

220 ected by interview and combined with isolate whole-genome sequencing to determine likelihood of house

221 eruginosa bloodstream isolates and performed whole-genome sequencing to identify accessory genomic el

222 We performed whole-exome and shallow whole-genome sequencing to identify genes and pathways p

223 ediated by foldback inversions combined with whole-genome sequencing to study their formation.

224 ARO colonization on NF admission, we applied whole-genome sequencing to track the spread of 4 ARO spe

225 in L. japonica was elucidated by integrating whole genome sequencing, transcriptomic analysis and bio

226 Methods: Within a prospective multicenter whole-genome sequencing trial (NCT01855477), 69 mPC pati

227 lating agents, as well as in whole-exome and whole-genome-sequenced tumors identified signatures high

228 were not randomized and received ultra-rapid whole-genome sequencing (urWGS).

229 d with conventional RT-PCR based methods and whole genome sequenced using the Illumina MiSeq platform

230 g genomic data, particularly when annotating whole-genome sequencing variants against a huge database

231 The availability of whole genome sequences was expected to supply essentiall

232 Whole genome sequencing was performed on 20 matched bloo

233 and detect potential transmission clusters, whole genome sequencing was performed on nasopharyngeal

234 Long-read whole genome sequencing was performed using Pacific Bios

235 ive RT-PCR primers/probe were developed, and whole genome sequencing was performed.

236 Whole genome sequencing was used to uncover a frame-shif

237 Whole-genome sequencing was performed on 388 isolates, i

238 Whole-genome sequencing was performed on blood-derived D

239 Using whole-genome sequencing we now identified a single rare

240 However, analysing the nuclear whole genome sequence, we observe likely large rare or u

241 By parent-offspring whole genome sequencing, we estimate a mutation rate (3.

242 Using whole genome sequencing, we identified a heterozygous fr

243 Using clinical whole genome sequencing, we show that AR binding sites h

244 Using over 15,000 whole-genome sequences, we find that negative selection

245 unction copy number (JCN) across 2,778 tumor whole-genome sequences, we uncovered three novel complex

246 using a combination of short- and long-read whole-genome sequencing, we found no significant associa

247 ingle nucleotide polymorphisms identified by whole genome sequencing were used to design a specific p

248 We performed whole genome sequence (WGS) analysis of lung function an

249 Whole genome sequence (WGS) data could transform our abi

250 ility, Multilocus Sequence Typing (MLST) and Whole Genome Sequencing (WGS) analysis.

251 Whole genome sequencing (WGS) and antimicrobial suscepti

252 Using tumor and germline whole genome sequencing (WGS) and RNA sequencing (RNAseq

253 Whole genome sequencing (WGS) can potentially provide a

254 Bulk whole genome sequencing (WGS) enables the analysis of tu

255 For the analysis, we used whole genome sequencing (WGS) Human datasets for which t

256 We present SNVs discovered by whole genome sequencing (WGS) of three Moroccans.

257 Here, we perform whole genome sequencing (WGS) on 21 patients with prolac

258 Here we assemble a set of 719 deep whole genome sequencing (WGS) samples (mean 42x) from 47

259 present here an unbiased approach combining whole genome sequencing (WGS) with patient-induced pluri

260 Whole genome sequencing (WGS), on the other hand, allows

261 calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively.

262 ethods, but there are plans for implementing whole genome sequencing (WGS).

263 rsity and characterization were performed by whole genome sequencing (WGS).

264 With the advent of whole genome-sequencing (WGS) studies, family-based desi

265 int information, or structural variants from whole-genome sequence (WGS) data.

266 the same wards within 7 days were chosen for whole-genome sequencing (WGS) and a phylogenetic analysi

267 the genomic landscape of myeloma using deep whole-genome sequencing (WGS) and develop a model that i

268 We performed whole-genome sequencing (WGS) and pan-genome analysis on

269 Here, we leverage whole-genome sequencing (WGS) and whole-genome bisulfite

270 Whole-genome sequencing (WGS) can improve assessment of

271 Whole-genome sequencing (WGS) can support surveillance b

272 Whole-genome sequencing (WGS) costs are falling, yet, ou

273 Whole-genome sequencing (WGS) data from 853 rhesus macaq

274 th BDQ- and DLM-resistant phenotypes using a whole-genome sequencing (WGS) data set from a collection

275 d comparison of P. aeruginosa isolates using whole-genome sequencing (WGS) data.

276 Whole-genome sequencing (WGS) has emerged as a powerful

277 Whole-genome sequencing (WGS) identified preincarceratio

278 tabolic relevance through high-depth (22.5x) whole-genome sequencing (WGS) in 1328 individuals.

279 Here we used whole-genome sequencing (WGS) in a national health syste

280 Whole-genome sequencing (WGS) is now routinely performed

281 Here we perform whole-genome sequencing (WGS) of 103 UM from all sites o

282 We undertook whole-genome sequencing (WGS) of 660 pneumococcal isolat

283 Whole-genome sequencing (WGS) of cfDNA allowed ultra-sen

284 (SV) in neuroblastoma using a combination of whole-genome sequencing (WGS) of tumor-normal pairs (n =

285 We apply whole-genome sequencing (WGS) to identify non-coding mut

286 l serotyping results by latex agglutination, whole-genome sequencing (WGS) with PneumoCaT, and DNA mi

287 ver, new sequencing approaches, particularly whole-genome sequencing (WGS), have dramatically changed

288 comparative genomic hybridization (CGH) and whole-genome sequencing (WGS), have greatly advanced the

289 ariation to whole-exome sequencing (WES) and whole-genome sequencing (WGS).

290 CR) was performed for specific pathogens and whole-genome sequencing (WGS).

291 of high throughput SNP-based genotyping and whole-genome sequencing (WGS).

292 issue samples based on low-coverage clinical whole-genome sequencing (WGS).

293 edium-throughput genotyping (31,811 SNPs) or whole-genome sequencing (WGS, 8.7 million SNPs).

294 ebsiella oxytoca infection was identified by whole-genome sequencing (WGS; later found to be part of

295 Established methods for whole-genome-sequencing (WGS) technology allow for the d

296 r the solubility limit were then analyzed by whole genome sequencing, which revealed prevalent point

297 semble methods using both real and synthetic whole-genome sequencing, whole-exome sequencing, and dee

298 ces per submission and the analysis of a new whole-genome sequence will take approximately 1 min.

299 n-day microbe hunters are combining pathogen whole-genome sequencing with epidemiological data to enh

300 ing a restoration genomics approach based on whole-genome sequencing with replicated space-for-time s