ライフサイエンスコーパス: whole-genome sequencing

1 found that 41 carried mcr-9 (validated using whole genome sequencing).

2 landers with genetic information (imputed or whole-genome sequencing).

3 , whole exome sequencing, and more recently, whole genome sequencing.

4 s, have not proved tractable with short-read whole genome sequencing.

5 he origin and evolution of this system using whole genome sequencing.

6 clinical isolates were processed for BMD and whole genome sequencing.

7 e readily selected, from single mutations to whole-genome sequencing.

8 sequencing panels as well as whole-exome and whole-genome sequencing.

9 lates were previously categorized via PCR or whole-genome sequencing.

10 have been analysed by both transcriptome and whole-genome sequencing.

11 etation of structural variants in the era of whole-genome sequencing.

12 rulence and antibiotic resistance assays and whole-genome sequencing.

13 osely related to the main outbreak strain by whole-genome sequencing.

14 variant by genome-wide association study and whole-genome sequencing.

15 criptomics, and karyotyped using single-cell whole-genome sequencing.

16 ated sources in NYS were characterized using whole-genome sequencing.

17 Cultured isolates underwent whole-genome sequencing.

18 g with K1 open reading frame Sanger and KSHV whole-genome sequencing.

19 ncluding multilocus typing of five genes and whole-genome sequencing.

20 genetic test with whole-exome sequencing or whole-genome sequencing.

21 is evolutionary process, we interrogated, by whole genome sequencing, 25 samples collected at autopsy

22 Whole genome sequencing (30X) and digital droplet PCR (d

23 Whole genome sequencing alerted us to the existence of g

24 lerated short-read aligner, can compute WGS (whole-genome sequencing) alignments ten times faster tha

25 However, the wide adoption of whole-genome sequencing also poses new challenges for pu

26 Here we performed whole-genome sequencing analyses of 426 individuals-comp

27 st-line approach, followed by a more refined whole genome sequencing analysis.

28 Here, by whole-genome sequencing analysis of 2,658 cancers as par

29 bility in MMR-deficient gliomas, single-cell whole-genome sequencing analysis of post-treatment hyper

30 Whole-genome sequencing analysis revealed no increase in

31 region on canine chromosome 33, followed by whole-genome sequencing analysis that revealed a long in

32 Whole genome sequencing and analysis showed a reduced ge

33 Whole genome sequencing and cytogenetics of experimental

34 ights into its biosynthesis were provided by whole genome sequencing and gene deletion studies, while

35 able SV discovery in non-model species using whole genome sequencing and report 15,483 high-confidenc

36 ased caution to address systematic biases in whole-genome sequencing and alignment.

37 lts were confirmed using pathogen isolation, whole-genome sequencing and antibiotic susceptibility te

38 om a high-caries risk study population using whole-genome sequencing and assess their association wit

39 Whole-genome sequencing and centromere mapping combined

40 estion, fluorescence-activated cell sorting, whole-genome sequencing and data analysis.

41 lysis provides results on the integration of whole-genome sequencing and deep phenotyping for clinica

42 nd rarer kidney cancer subtypes, integrating whole-genome sequencing and DNA methylation data.

43 Representative isolates underwent whole-genome sequencing and had their virulence tested i

44 By combining whole-genome sequencing and phenotypic susceptibility da

45 Whole-genome sequencing and phylogenetic analysis of 388

46 Whole-genome sequencing and SNP-level analysis was condu

47 Using serial MRI/3D-reconstruction, whole-genome sequencing and spectral karyotyping-based s

48 The polyclonal nature of strains revealed by whole-genome sequencing and the apparent lack of epidemi

49 Data from whole-genome sequencing and transcriptome studies were t

50 Through a combination of whole-genome sequencing and transcriptomics, we showed t

51 Using whole-genome sequencing and tribal fishery sampling of C

52 itulates mutational signatures identified by whole genome sequencing, and will ultimately allow the s

53 th genomic data from whole exome sequencing, whole genome sequencing, and/or array-based imputation.

54 54 y [range 20 to 89+]; 70.6% European) had whole-genome sequencing, and were deeply phenotyped usin

55 Thus, using a cohort-based whole-genome-sequencing approach in the diagnosis of PID

56 Whole-exome and whole-genome sequencing are becoming financially feasibl

57 crobial resistance determination, such as by whole-genome sequencing, are required.

58 However, the increasing application of whole-genome sequencing as a diagnostic tool is leading

59 t suspected, adopting whole-exome sequencing/whole-genome sequencing as a first-line test should be c

60 d 27 species from human donors and performed whole-genome sequencing assembly and annotation.

61 ients were tested by broth microdilution and whole genome sequencing at a central laboratory.

62 tions, and duplications were genotyped using whole-genome sequencing-based data.

63 ata to create the largest, to our knowledge, whole-genome-sequencing-based structural variant resourc

64 Whole-genome sequencing can be used to estimate subclona

65 n testing for five lipid traits in two UK10K whole genome sequencing cohorts, hypothesizing that cis-

66 Whole-genome sequencing confirmed distinct species ident

67 Surveillance strategies based on whole genome sequencing could help with the early identi

68 Whole genome sequencing coupled with an outbreak-strain-

69 read signals for potential SV breakpoints in whole genome sequencing data and proposes a probabilisti

70 Whole genome sequencing data did not identify a strain g

71 Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 3

72 q and RNA-seq, and then integrate these with whole genome sequencing data from 232 OCs.

73 Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancer across 38

74 Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38

75 Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38

76 Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38

77 Whole genome sequencing data from cases and controls wer

78 Mining RNA-seq and whole genome sequencing data from other species of the R

79 The multi-tissue gene expression and whole genome sequencing data generated by the Genotype-T

80 ions will allow for better interpretation of whole genome sequencing data in the large number of pati

81 fill this gap, we extend TWAS to integrating whole genome sequencing data with transcriptomic data fo

82 Using the GTEx whole genome sequencing data, we identify 20,545 high-qu

83 o accurately assemble organelle genomes from whole genome sequencing data.

84 uild accurate models to predict AMR based on whole genome sequencing data.

85 Genetic variants were examined using whole-genome sequencing data among survivors of African

86 Genomes (PCAWG) Consortium, which aggregated whole-genome sequencing data and RNA sequencing from a c

87 Short-read whole-genome sequencing data are often applied to large-

88 Utilizing high-coverage whole-genome sequencing data as part of the Trans-Omics

89 Whole-genome sequencing data can be used to distinguish

90 Our interrogation of the whole-genome sequencing data for 215 breast tumors catal

91 es and quality control measures for handling whole-genome sequencing data for mutational signature an

92 study for impaired spermatogenesis utilizing whole-genome sequencing data from 167 nonirradiated male

93 Using public whole-genome sequencing data from 2,606 samples from dif

94 Cancer Genome Atlas (TCGA), which aggregated whole-genome sequencing data from 2,658 cancers across 3

95 Cancer Genome Atlas (TCGA), which aggregated whole-genome sequencing data from 2,658 cancers across 3

96 f Whole Genomes Consortium, which aggregated whole-genome sequencing data from 2,658 cancers across 3

97 Genomes (PCAWG) Consortium, which aggregated whole-genome sequencing data from 2658 cancers across 38

98 Genomes (PCAWG) consortium, which aggregated whole-genome sequencing data from 2658 cancers across 38

99 We analyze whole-genome sequencing data from 268 patients to catalo

100 Using computational analysis of whole-genome sequencing data from 3,212 cancer patients,

101 We analyzed whole-genome sequencing data from 43 202 Icelanders.

102 Using whole-genome sequencing data from 519 unrelated individu

103 We collected germline whole-genome sequencing data from IMvigor211, a recent p

104 We applied SBMClone to single-cell whole-genome sequencing data from two breast cancer pati

105 ural variant caller utilizing low-depth (8X) whole-genome sequencing data generated by Oxford Nanopor

106 Although whole-genome sequencing data helped to personalize treat

107 hen using dense imputation from multi-ethnic whole-genome sequencing data in admixed Hispanics/Latino

108 a new theoretical framework that, applied to whole-genome sequencing data of healthy tissue and cance

109 feasibility of using Oxford Nanopore MinION whole-genome sequencing data of Mycobacterium tuberculos

110 Whole Genomes (PCAWG) Consortium, we dissect whole-genome sequencing data of over 2500 matched tumor-

111 high sequence and structural diversity from whole-genome sequencing data remains highly challenging.

112 836).Methods: We used admixture-mapping and whole-genome sequencing data to discover genomic regions

113 lassifiers have successfully been applied to whole-genome sequencing data to identify genetic determi

114 y in PAH we integrated deep phenotyping with whole-genome sequencing data using Bayesian statistics.

115 Here, we combine long- and short-read whole-genome sequencing data with recent assembly approa

116 Using matched whole-genome sequencing data, we associated several cate

117 otransposon insertions for both targeted and whole-genome sequencing data.

118 personal genetics company 23andMe, Inc. and whole-genome sequencing data.

119 TypeTE - which genotypes Alu insertions from whole-genome sequencing data.

120 ross 2,658 tumors from 38 cancer types using whole-genome sequencing data.

121 and 60-80% of indels detected in human brain whole-genome sequencing data.

122 of structural variant (SV) breakpoints from whole-genome sequencing data.

123 We also applied our methodology to a TOPMed whole-genome sequencing dataset with 897 asthmatic trios

124 newly inferred D genes by analyzing diverse whole genome sequencing datasets and haplotyping heteroz

125 o test for genetic differences, we performed whole genome sequencing, deep mitochondrial DNA (mtDNA)

126 Unbiased whole genome sequencing demonstrates high specificity of

127 characteristics, and performed mycobacterial whole-genome sequencing, dormancy phenotyping and drug-s

128 he B10K ("Bird 10,000 Genomes") consortium's whole-genome sequencing effort, we have included 363 ann

129 It highlights the role of whole-genome sequencing, expanded phenotypic drug suscep

130 ts by RNA sequencing, followed by additional whole-genome sequencing experiments.

131 Whole-genome sequencing facilitated the detection of the

132 We performed whole genome sequencing for two American minks with Moyl

133 A key goal of whole-genome sequencing for studies of human genetics is

134 r dysenteric diarrhea and endorse the use of whole-genome sequencing for sustained surveillance of NT

135 We measured sperm mosaicism using deep-whole-genome sequencing, for variants both present in an

136 (CAD) reference distribution was built using whole-genome sequencing from 1,522 Indian individuals, a

137 This study used imputed whole-genome sequencing from the Trans-Omics for Precisi

138 Whole-genome sequencing has enhanced surveillance and fa

139 As access to whole-genome sequencing has grown, greater amounts of mo

140 Short- and long-read whole-genome sequencing highlighted a duplication involv

141 While whole genome sequencing holds promise, it is not yet fea

142 ction and characterizing the viral load, RSV whole-genome sequencing, host immune response, and trans

143 Whole genome sequencing in multiplex families, proband-p

144 re we address these challenges by performing whole-genome sequencing in a large PID cohort of 1,318 p

145 Whole-genome sequencing in one affected dog and its obli

146 d MFRP and PRSS56 testing in 20 families and whole-genome sequencing in one family.

147 We also show that Hi-C can supplement whole-genome sequencing in structure variant detection b

148 e generated and analyzed, and how SARS-CoV-2 whole-genome sequencing, in combination with epidemiolog

149 ts and saline flushes were highly related by whole-genome sequencing, indicating a common source.

150 scan of the entire cohort, in parallel with whole-genome sequencing, methylation, and other 'omics a

151 mCRPC biopsies, using targeted and low-pass whole-genome sequencing (n = 52).

152 i-locus tandem repeat analysis (n = 719) and whole-genome sequencing (n = 816) of Escherichia coli de

153 mpared with 33.6% for whole-exome sequencing/whole-genome sequencing (n=143) giving an overall yield

154 We use whole genome sequencing of 16 independent isolates to id

155 e analyzed 6.8 million variants derived from whole genome sequencing of 160 islet autoantibody positi

156 noma occurring on palms, soles or nail beds, whole genome sequencing of 87 tumors with matching trans

157 We performed whole genome sequencing of 97 trios of Ashkenazi Jewish

158 Here we have performed whole genome sequencing of consecutive M. tuberculosis i

159 Whole genome sequencing of germline DNA from 51 members

160 ished a robust SWGA approach that can assist whole genome sequencing of P. malariae, and thereby faci

161 Whole genome sequencing of paired isolates was used to i

162 SWGA enables the successful whole genome sequencing of samples with low parasite den

163 Whole genome sequencing of select transformants demonstr

164 AD, we performed a genetic screen from deep whole genome sequencing of the large NIMH family-based A

165 MIC, pDST and whole genome sequencing of the pncA, rpsA and panD genes

166 Through whole-genome sequencing of 13 melanoma metastases sample

167 We conducted whole-genome sequencing of 27 domesticated goldfish stra

168 hmania braziliensis species complex based on whole-genome sequencing of 67 isolates from 47 localitie

169 Therefore, whole-genome sequencing of 756 child-parent trios of Eur

170 Shallow whole-genome sequencing of 777 biopsies, sampled from 88

171 We conducted whole-genome sequencing of all 1,575 available GAS macro

172 We conducted whole-genome sequencing of all animals using an Illumina

173 Here we used whole-genome sequencing of clonal cell isolates that dev

174 Whole-genome sequencing of clonal organoids before and a

175 ngle-cell DNA sequencing technologies enable whole-genome sequencing of hundreds to thousands of indi

176 Since whole-genome sequencing of many crops has been achieved,

177 predictions of this hypothesis by performing whole-genome sequencing of multiple independent invasive

178 Here, Whole-Genome Sequencing of Mycobacterium bovis isolated

179 Whole-genome sequencing of NTTB isolates revealed varied

180 e used this workflow to perform targeted and whole-genome sequencing of small populations of cells (t

181 We performed whole-genome sequencing of the SKBR3 breast cancer cell

182 Whole-genome sequencing of uncultured eukaryotic genomes

183 dilution AST with seven antibiotics and for whole-genome sequencing of up to 5,000 isolates.

184 Using whole-genome sequencing of zebrafish mutants isolated in

185 We performed whole genome sequencing on isolates from early pediatric

186 We performed whole-genome sequencing on food and clinical isolates.

187 egion of a genome, are readily obtained from whole-genome sequencing or microarrays.

188 f this intervention in a model that compared whole-genome sequencing plus current practice versus cur

189 The large-scale availability of whole-genome sequencing profiles from bulk DNA sequencin

190 Whole-genome sequencing projects are increasingly popula

191 ly longer sequence reads, which when used in whole-genome sequencing projects have yielded better rep

192 al resistance (AMR), classic genotyping, and whole-genome sequencing results.

193 Whole genome sequencing revealed differences in putative

194 Whole-genome sequencing reveals the absence of off-targe

195 rehensive proteogenomics analysis, including whole-genome sequencing, RNA sequencing, and proteomics

196 Rapid whole genome sequencing (rWGS) of peripheral blood has b

197 was a randomized, controlled trial of rapid whole-genome sequencing (rWGS) or rapid whole-exome sequ

198 VAPOR retrieved references for 257 real whole-genome sequencing samples with a mean of >99.8% id

199 At present, based on whole genome sequencing, sequences and genes annotation

200 31 patients were examined by culture, qPCR, whole genome sequencing, serotyping, and reverse transcr

201 Large-scale whole-genome sequencing studies have enabled the analysi

202 for analyzing very large cohort and biobank whole-genome sequencing studies of continuous and dichot

203 as9-independent deamination and validate via whole-genome sequencing that YE1, a narrowed-window CBE

204 ella Typhi isolates from India were found by whole genome sequencing to be closely related to the 201

205 Here, we used whole genome sequencing to characterise Pseudomonas aeru

206 Here we use C. elegans whole genome sequencing to systematically quantify the c

207 In this study, we used whole-genome sequencing to analyze a large collection of

208 ected by interview and combined with isolate whole-genome sequencing to determine likelihood of house

209 We use whole-genome sequencing to examine the origin and adapta

210 eruginosa bloodstream isolates and performed whole-genome sequencing to identify accessory genomic el

211 We performed whole-exome and shallow whole-genome sequencing to identify genes and pathways p

212 Here, we use whole-genome sequencing to investigate within-host micro

213 ediated by foldback inversions combined with whole-genome sequencing to study their formation.

214 ARO colonization on NF admission, we applied whole-genome sequencing to track the spread of 4 ARO spe

215 k, and environmental investigations and used whole-genome sequencing to type Listeria monocytogenes i

216 in L. japonica was elucidated by integrating whole genome sequencing, transcriptomic analysis and bio

217 Methods: Within a prospective multicenter whole-genome sequencing trial (NCT01855477), 69 mPC pati

218 were not randomized and received ultra-rapid whole-genome sequencing (urWGS).

219 g genomic data, particularly when annotating whole-genome sequencing variants against a huge database

220 Whole genome sequencing was performed in 197 probands wi

221 Whole genome sequencing was performed on 20 matched bloo

222 and detect potential transmission clusters, whole genome sequencing was performed on nasopharyngeal

223 Long-read whole genome sequencing was performed using Pacific Bios

224 ive RT-PCR primers/probe were developed, and whole genome sequencing was performed.

225 Whole genome sequencing was used to uncover a frame-shif

226 Whole-genome sequencing was performed on 388 isolates, i

227 Whole-genome sequencing was performed on blood-derived D

228 Using whole-genome sequencing we now identified a single rare

229 By parent-offspring whole genome sequencing, we estimate a mutation rate (3.

230 Using whole genome sequencing, we identified a heterozygous fr

231 Using clinical whole genome sequencing, we show that AR binding sites h

232 using a combination of short- and long-read whole-genome sequencing, we found no significant associa

233 Here, using whole-genome sequencing, we show that normal human endom

234 ingle nucleotide polymorphisms identified by whole genome sequencing were used to design a specific p

235 ility, Multilocus Sequence Typing (MLST) and Whole Genome Sequencing (WGS) analysis.

236 Whole genome sequencing (WGS) and antimicrobial suscepti

237 Using tumor and germline whole genome sequencing (WGS) and RNA sequencing (RNAseq

238 Whole genome sequencing (WGS) can potentially provide a

239 eration technologies, it is conceivable that whole genome sequencing (WGS) could be applied to routin

240 fic LINE-1 (L1Hs) insertions from short-read whole genome sequencing (WGS) data; however, they have l

241 Bulk whole genome sequencing (WGS) enables the analysis of tu

242 Whole genome sequencing (WGS) has enabled the discovery

243 For the analysis, we used whole genome sequencing (WGS) Human datasets for which t

244 from 2780 highly curated cancer genomes with whole genome sequencing (WGS) in 37 cancer types/subtype

245 s of somatic passenger mutations detected in whole genome sequencing (WGS) of 2606 tumours representi

246 We present SNVs discovered by whole genome sequencing (WGS) of three Moroccans.

247 Here, we perform whole genome sequencing (WGS) on 21 patients with prolac

248 Here we assemble a set of 719 deep whole genome sequencing (WGS) samples (mean 42x) from 47

249 Here we use whole genome sequencing (WGS) to investigate whether tre

250 present here an unbiased approach combining whole genome sequencing (WGS) with patient-induced pluri

251 Whole genome sequencing (WGS), on the other hand, allows

252 calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively.

253 ethods, but there are plans for implementing whole genome sequencing (WGS).

254 otypic antimicrobial resistance profiles and whole genome sequencing (WGS).

255 rsity and characterization were performed by whole genome sequencing (WGS).

256 With the advent of whole genome-sequencing (WGS) studies, family-based desi

257 the same wards within 7 days were chosen for whole-genome sequencing (WGS) and a phylogenetic analysi

258 the genomic landscape of myeloma using deep whole-genome sequencing (WGS) and develop a model that i

259 We performed whole-genome sequencing (WGS) and pan-genome analysis on

260 Here, we performed whole-genome sequencing (WGS) and viral capture-based se

261 Here, we leverage whole-genome sequencing (WGS) and whole-genome bisulfite

262 Whole-genome sequencing (WGS) can improve assessment of

263 Whole-genome sequencing (WGS) can support surveillance b

264 Whole-genome sequencing (WGS) costs are falling, yet, ou

265 Ig characterization cannot be extracted from whole-genome sequencing (WGS) data due to the inherent c

266 Whole-genome sequencing (WGS) data from 853 rhesus macaq

267 th BDQ- and DLM-resistant phenotypes using a whole-genome sequencing (WGS) data set from a collection

268 d comparison of P. aeruginosa isolates using whole-genome sequencing (WGS) data.

269 Whole-genome sequencing (WGS) has emerged as a powerful

270 Whole-genome sequencing (WGS) identified preincarceratio

271 tabolic relevance through high-depth (22.5x) whole-genome sequencing (WGS) in 1328 individuals.

272 Here we used whole-genome sequencing (WGS) in a national health syste

273 Whole-genome sequencing (WGS) is now routinely performed

274 liability of this assay was confirmed by the whole-genome sequencing (WGS) of 10 base editors in rege

275 Here we perform whole-genome sequencing (WGS) of 103 UM from all sites o

276 We undertook whole-genome sequencing (WGS) of 660 pneumococcal isolat

277 Whole-genome sequencing (WGS) of cfDNA allowed ultra-sen

278 (SV) in neuroblastoma using a combination of whole-genome sequencing (WGS) of tumor-normal pairs (n =

279 The dataset consisted of 386 whole-genome sequencing (WGS) samples.

280 Whole-genome sequencing (WGS) surveillance of clinical b

281 We apply whole-genome sequencing (WGS) to identify non-coding mut

282 Recently, labs have applied whole-genome sequencing (WGS) to investigate this furthe

283 l serotyping results by latex agglutination, whole-genome sequencing (WGS) with PneumoCaT, and DNA mi

284 ver, new sequencing approaches, particularly whole-genome sequencing (WGS), have dramatically changed

285 comparative genomic hybridization (CGH) and whole-genome sequencing (WGS), have greatly advanced the

286 inical specimens, we compared phenotypic and whole-genome sequencing (WGS)-based detection of resista

287 ariation to whole-exome sequencing (WES) and whole-genome sequencing (WGS).

288 CR) was performed for specific pathogens and whole-genome sequencing (WGS).

289 of high throughput SNP-based genotyping and whole-genome sequencing (WGS).

290 issue samples based on low-coverage clinical whole-genome sequencing (WGS).

291 edium-throughput genotyping (31,811 SNPs) or whole-genome sequencing (WGS, 8.7 million SNPs).

292 ebsiella oxytoca infection was identified by whole-genome sequencing (WGS; later found to be part of

293 Established methods for whole-genome-sequencing (WGS) technology allow for the d

294 r the solubility limit were then analyzed by whole genome sequencing, which revealed prevalent point

295 wered in recent years by the availability of whole-genome sequencing, which has allowed a new focus o

296 Whole-genome sequencing, whole exome-sequencing and tran

297 semble methods using both real and synthetic whole-genome sequencing, whole-exome sequencing, and dee

298 sion medicine study with a goal to integrate whole-genome sequencing with deep phenotyping.

299 n-day microbe hunters are combining pathogen whole-genome sequencing with epidemiological data to enh

300 ing a restoration genomics approach based on whole-genome sequencing with replicated space-for-time s