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1 ive protein-containing ordered nanomaterials with desired 2D and 3D organizations.
2 ficiently and precisely processed into gRNAs with desired 5' targeting sequences in vivo, which direc
3  catenated SJTU-219 or noncatenated SJTU-220 with desired acs net.
4 tic small molecule catalysts can be designed with desired active site composition but do not yet disp
5 important avenue for obtaining novel enzymes with desired activities and properties.
6 en conducted to find multifunctional ligands with desired activities at three receptors.
7               The identification of proteins with desired activities, especially from complex samples
8  the pathways most likely to yield compounds with desired activities.
9  a general approach to advanced NP catalysts with desired activity and durability control for practic
10 engineering modified FGF9 subfamily ligands, with desired activity for use in both basic and translat
11  identifying structural classes of compounds with desired activity in lieu of lone compounds.
12 s with experiments in the quest for surfaces with desired activity, an advanced concept in nanoscale
13  glycan structures for individual antibodies with desired activity, we have developed an effective me
14 nctional structures that bind target ligands with desired affinities in physiological concentrations
15 imal single chain fragment variables (scFvs) with desired affinity characteristics for incorporation
16 s (HSCs) is an alternative to create T cells with desired Ag specificity, because in this case expres
17 g devices must be fixed at desired locations with desired alignment.
18 linearized dynamics, sinusoidal oscillations with desired amplitudes and periods, and a complex wavef
19 nces made in the development of new polymers with desired and controllable properties.
20 e for breeding strategies to generate plants with desired architectural and nutritional characteristi
21 for integrating support cells into a conduit with desired architectures is wanted.
22 ereolithographic printing to form a scaffold with desired architectures.
23  method for the generation of antimicrobials with desired attributes.
24 molecular properties or design new molecules with desired attributes.
25 biomaterials of required mechanical strength with desired balance between stiffness and plasticity.
26 al design of photosensitive heterostructures with desired band alignment, three orders of magnitude e
27 mulated discovery campaign to find materials with desired band gap values.
28 ic biology to construct synthetic cocultures with desired behavior.
29 g the ability to rationally engineer operons with desired behaviors.
30 is unable to quantitatively produce aptamers with desired binding affinities and requires multiple ro
31 strategies for isolating customized aptamers with desired binding profiles.
32 practical use in the engineering of peptides with desired binding properties and will aid in the inte
33  also enables rapid design of novel aptamers with desired binding properties.
34  and dual-peptide functionalized Ti surfaces with desired biocompatibility or/and antimicrobial activ
35 the potential to uncover cryptic metabolites with desired biological activities that are hidden in mi
36 n developing and optimizing de novo peptides with desired biological activities, DBAASP offers severa
37 ls for the purpose of screening for peptides with desired biological activity.
38 ing moiety on their surface, or supplemented with desired biological activity.
39 o sort fluorescently labeled particles/cells with desired biological properties.
40 ed the chances for finding binding molecules with desired biological properties; however, achieving d
41 chniques are in development to load exosomes with desired cargo, such as proteins or miRNAs, to achie
42 zation of optoelectronic material candidates with desired carrier dynamics and optical properties.
43 nation of naturally occurring enzyme modules with desired catalytic properties.
44 new avenues for ML discovery of novel motifs with desired catalytic properties.
45 oughput biological data means that even data with desired cell lines, tissue types, or molecular targ
46 rement allows early selection of a cell line with desired characteristics (e.g., oligosaccharide prof
47 hts the potential for engineering organelles with desired characteristics for metabolic engineering.
48          However, generating stable droplets with desired characteristics typically requires labor-in
49 bilities to conveniently select participants with desired characteristics, and participants from diff
50 iate process conditions to produce a biochar with desired characteristics.
51 will help in the design of modified proteins with desired characteristics.
52  their abilities to synthesize nanoparticles with desired characteristics.
53 ed, prompting a search for novel AAV capsids with desired characteristics.
54                      The design of catalysts with desired chemical and thermal properties is viewed a
55 re, as well as generate candidate structures with desired chemical properties.
56 successfully generates stable, new materials with desired chemistry, symmetry and mechanical, electro
57  fuels a growing interest in developing MOFs with desired chemomechanical functions and presents deta
58 ynthesizing uniform inorganic nanostructures with desired chirality using a scalable method remains c
59 n the construction of discrete AuNP clusters with desired chirality.
60 t for the design of plasmonic nanostructures with desired chiroptical properties.
61 y to new assembled inorganic suprastructures with desired chiroptical response for wide-ranging funct
62 also aid in the design of synthetic heparins with desired clearance rates.
63 s useful for engineering synthetic materials with desired colors without laborious trial-and-error ex
64 ter-soluble nearly monodisperse nanocrystals with desired composition and architecture, including cor
65 rs to achieve high quality crystalline films with desired composition.
66 ent approach to fabrication of nanocatalysts with desired compositional distributions and performance
67 igned to produce protein-spinach ingredients with desired concentration of compounds and bioaccessibi
68 solid phase to furnish polydiacetylene (PDA) with desired control over the chiroptical properties.
69 l unable to provide automatic gene discovery with desired correctness.
70  manufacturing future energy-storage devices with desired deformability together with high performanc
71 uide the design of proteins and therapeutics with desired degradation and quality control properties.
72 -extracting process in fabricating membranes with desired desalination performance.
73 en the main RTSD for more than three decades with desired detection properties.
74 emission lines covering the visible spectrum with desired directionality, thus providing a promising
75 their potential to obtain combined therapies with desired drug release profiles.
76 ottom-up, molecular-level design of crystals with desired dynamic and mechanical properties at the ma
77 ynthesize relatively monodisperse nanoprisms with desired edge lengths in the 30-120 nm range.
78 d bone growth impairment without interfering with desired effects of GCs.
79 e been a major hurdle in designing therapies with desired efficacy and acceptable toxicity.
80 for kidney disease treatment can be achieved with desired efficacy and precision.
81    The ultimate goal is to obtain a material with desired elastic properties in as few iterations as
82 d for the preparation of electrode materials with desired electrical and electrochemical properties f
83 ly due to the lack of efficient active sites with desired electronic states.
84 provided robust antilymphoma efficacy, along with desired eradication of the bone marrow niche, such
85 ural operons and to design synthetic operons with desired expression level ratios.
86 ters and engineering synthetic gene circuits with desired expression properties.
87 teps required to obtain dendritic structures with desired features.
88 ein-protein interactions, design of proteins with desired flexibility or rigidity, and prediction of
89 on maps could guide design of novel proteins with desired function.
90 ers flexibility for direct functionalization with desired functional groups (e.g., -COCH3, fluorescei
91 posed of short organic chains and terminated with desired functional groups are attractive for modify
92 c residues permits synthesis of naphthalenes with desired functional groups.
93 ns reliably is critical for realizing states with desired functional properties.
94 esent results pave a way to design materials with desired functionalities at oxide interfaces.
95 ated a variety of pentasubstituted pyridines with desired functionalities for further chemical manipu
96 ic control to self-organized superstructures with desired functionalities is an important leap necess
97   Designing many nonrepetitive genetic parts with desired functionalities remains a difficult challen
98                   Designing genetic networks with desired functionalities requires an accurate mathem
99 phase evolution allow manipulating materials with desired functionalities, and can be developed via r
100 thesis of mechanically interlocked materials with desired functionalities.
101 for developing all-optical molecular devices with desired functionalities.
102 nge of possibilities for designing materials with desired functionalities.
103 nstruction of devices, systems and organisms with desired functionality based on modular well-charact
104                         Engineering proteins with desired functions and biochemical properties is piv
105  generating exosome-based immunotherapeutics with desired functions and properties.
106                However, engineering proteins with desired functions for practical applications remain
107 ing these models to generate novel sequences with desired functions remains challenging.
108 lding blocks for fabricating complex devices with desired functions.
109 cid sequences that fold into stable proteins with desired functions.
110 ction as a platform, to screen the positions with desired functions.
111 form the precise synthesis of nanostructures with desired functions.
112  making it challenging to design communities with desired functions.
113 n for engineering bespoke artificial viruses with desired functions.
114 ore conformationally stable helical peptoids with desired functions.
115 eptoids enable the future design of polymers with desired functions.
116 his resulted in identification of compound 4 with desired FXIa inhibitory potency and good oral bioav
117 lties and time required in generating models with desired genetic modifications.
118 suggests ways to engineer biological systems with desired genetic properties.
119 gineering cell lines to produce therapeutics with desired glycosylation patterns.
120 a useful tool for the development of strains with desired growth and production properties.
121 transient chiral media in the visible regime with desired handedness upon the inhomogeneous generatio
122                Ultra-white SCS-derived CNCs, with desired hydrophilicity were 327.1 nm particles with
123      Efficiently assembling heterostructures with desired interface properties, stability, and facile
124 s as an express method for selecting sensors with desired kinetic characteristics.
125 Fbeta1 induction in keratinocytes temporally with desired levels.
126 ctive synthesis of aqueous organic solutions with desired liquid-solid phase equilibria could drive p
127 of complex three-dimensional (3D) structures with desired materials.
128 l recyclability built into their performance with desired mechanical and barrier properties, thus rep
129       In this study, alginate hydrogel foams with desired mechanical and radiological properties were
130 d to design and tailor these microstructures with desired mechanical responses under extreme environm
131 hemical modifications to construct materials with desired mechanical, biological, and structural prop
132 w therapeutic nucleoside/nucleotide prodrugs with desired metabolic profiles.
133  an 6000-fold improvement in ASBT inhibition with desired minimal systemic exposure of this locally a
134 es to predictably access conjugated polymers with desired Mn and highlights the importance of optimiz
135 ation of polymers that may be functionalized with desired moieties arrayed in a controlled fashion, t
136 abrication of other core-shell nanocatalysts with desired monolayer shells for various catalytic reac
137           The programs identify the vesicles with desired morphology and analyzes the data automatica
138  The program can automatically identify GUVs with desired morphology and perform intensity-based calc
139 ovements generated by electrical stimulation with desired movements yielded root mean squared errors
140 ot only easily identifies developing animals with desired mutations but also efficiently quantifies t
141 me 3 (ORF3), we constructed five HEV mutants with desired mutations in the ORF1 and ORF2 junction reg
142 stem can be used to rapidly engineer viruses with desired mutations to study the virus in vitro and i
143          Four blue-emitting thienyltriazoles with desired N and O coordination atoms were prepared in
144 vent such unintentional doping in structures with desired n-type conductivity.
145 This powerful tool uses a pre-existing guide with desired nanoscale features to direct the formation
146 esting, diverse, and unconventional peptides with desired nanostructure assembly.
147 y networks as leak propagation can interfere with desired network function.
148 e insights may assist in designing promoters with desired noise levels.
149  protein redesign can help engineer proteins with desired novel function.
150 s further optimization to obtain a candidate with desired nuclear magnetic resonance (NMR) properties
151 r constructing oscillating reaction networks with desired OCs.
152        The platform optimized nanostructures with desired optical properties by combining experiments
153 1 enables to construct nano/micro structures with desired optoelectronic properties.
154 oaches has enabled the creation of materials with desired organization of nanoscale components.
155 oves with widths as small as 40 nm and 60 nm with desired orientation and length are fabricated.
156 lization retaining their biological activity with desired orientation, to facilitate electron transfe
157 r, the Nash equilibrium may not always align with desired outcomes within the broader system.
158 chemical deposition, various solid materials with desired patterns can be produced.
159 pressure propels and stabilizes the nanofilm with desired patterns.
160  modular construction of foldable structures with desired performance and manufacturing scalability.
161 e complementary polymers can create products with desired performance but present challenges to end-o
162                            Finding molecules with desired pharmaceutical properties is crucial in dru
163 caffolds for the kappa-opioid receptor (KOR) with desired pharmacological activities.
164      The search for selective opioid ligands with desired pharmacological potency and improved safety
165 knowledge-based discovery of novel compounds with desired pharmacological properties.
166 puter-assisted "de novo" design of molecules with desired pharmacological properties.
167 g interleukin-1 receptor antagonist (IL-1Ra) with desired phase and amplitude.
168 ights and limitations for designing new GFPs with desired phenotypes.
169 n efficiently guide engineering of receptors with desired phenotypes.
170 penones enable background-free Raman imaging with desired photocontrollable features.
171 nce for designing new Eu(2+)-doped phosphors with desired photoluminescence properties.
172                  In principle, photoswitches with desired photophysical properties like high isomeriz
173 er structural classes of inorganic molecules with desired physical and chemical properties.
174 economical method to produce building blocks with desired physical properties for new generation of e
175  essential for the syntheses of nanocrystals with desired physical properties.
176 ost of the major pathogenic features of acne with desired physicochemical traits.
177  insights can be used to engineer antibodies with desired PK properties.
178 ve strategy for designing auxetic structures with desired porosity.
179 bout the rational design of partial agonists with desired potencies and maximum activities.
180 he first MTJ is driven to a resistance state with desired probability via a current or voltage that g
181 to synthesize new artificial systems endowed with desired properties and functions.
182 etic approaches used for obtaining materials with desired properties and the factors to be considered
183 esolution to support the design of compounds with desired properties and the interpretation of existi
184  researchers who aim to synthesize RNA pools with desired properties and/or experiment in silico with
185    Prediction and discovery of new materials with desired properties are at the forefront of quantum
186 g of the DRL agent, material microstructures with desired properties can be achieved by the framework
187                                Novel enzymes with desired properties can be created and selected from
188 overy of a novel RORy antagonist (SHR168442) with desired properties for a topical drug.
189 hnique that can be used to identify proteins with desired properties from both natural proteome and c
190  been developed to select or screen proteins with desired properties from libraries of mutants.
191 ach to construct customizable supraparticles with desired properties from molecular building blocks o
192 d to the identification of protein sequences with desired properties from various natural proteome li
193 e system upon adding selective nanomaterials with desired properties in a multicomponent mixture foll
194 ing system to identify novel SaCas9 variants with desired properties in human cells.
195  leverages fundamental mechanisms associated with desired properties in nature and adapts them to the
196 ic control to self-organized superstructures with desired properties is an important leap necessary i
197           The design of functional materials with desired properties is essential in driving technolo
198 cs is difficult, and searching for sequences with desired properties is labour-intensive and time-con
199                             Genetic elements with desired properties were isolated using biologically
200 ry evolution has generated many biomolecules with desired properties, but a single round of mutation,
201  regLM, a framework to design synthetic CREs with desired properties, such as high, low, or cell type
202 ial for the rational design of mechanophores with desired properties, yet SMARs in noncovalent mechan
203 that can be modified to generate polymerases with desired properties.
204  the construction of synthetic gene networks with desired properties.
205 o genes and genomes to create novel variants with desired properties.
206 rs to specify eukaryotic regulatory networks with desired properties.
207 tion relations and developing novel proteins with desired properties.
208 es to the selection of proteins and peptides with desired properties.
209 be an effective method for evolving proteins with desired properties.
210 elerate the design of interfacial structures with desired properties.
211 ons at a distance can yield variant proteins with desired properties.
212  proteins and peptides and to select members with desired properties.
213 tions of genes and to identify gene products with desired properties.
214 eloped to accelerate the design of molecules with desired properties.
215 ating microemulsions for a given application with desired properties.
216 the possibility of designing new biopolymers with desired properties.
217 ient descent and design biochemical networks with desired properties.
218 fs that can be stacked together into systems with desired properties.
219 tifying regions that correspond to molecules with desired properties.
220  materials, enabling the design of materials with desired properties.
221  optimal target sequences to produce systems with desired properties.
222 ign of other multicomponent material systems with desired properties.
223 may help in the rational design of compounds with desired properties.
224 e the discovery of optimal salt compositions with desired properties.
225 ftly designing antimicrobial peptides (AMPs) with desired properties.
226 ) approach in constructing robust structures with desired properties.
227 esigned to achieve this anisotropic behavior with desired properties.
228 onships and rationally design nanostructures with desired properties.
229 olbox used for generating metal nanocrystals with desired properties.
230 ctors is the key for tailoring nanoparticles with desired properties.
231 uired to design and prepare polyphosphazenes with desired properties.
232 tools can guide the search for new materials with desired properties.
233 ies in achieving subtype-selective compounds with desired properties.
234 enable the targeted preparation of materials with desired properties.
235 versity and for identifying protein variants with desired properties.
236 (HTS) is important for identifying molecules with desired properties.
237 s for effective endogenous bone regeneration with desired quality.
238 table and ecologically resilient communities with desired quantitative attributes.
239 yrins and could be used to engineer proteins with desired reactivity or functionality.
240 owledge, we could rationally design peptides with desired residues to manipulate peptide-graphene int
241 iscovering K(ATP) channel pharmacochaperones with desired reversible inhibitory effects to permit fun
242  imine reductase and nitroreductase variants with desired selectivity modifications, and a high-perfo
243              To inhibit pathogenic proteases with desired selectivity, monoclonal antibodies (mAbs) h
244 which could be used to design novel peptides with desired self-assembly properties, by tuning a few p
245               An array of metallic nanowires with desired separation and width determined by the appl
246 imers then enable the retrieval of molecules with desired sequences by PCR.
247 cale chemical species, such as nanoparticles with desired shapes and compositions, offers the excitin
248 vested in the construction of nanostructures with desired shapes and physical and chemical properties
249 tive for creating a wide range of structures with desired shapes.
250 , however, hampering efforts to design drugs with desired signaling profiles.
251 ly determined mechanism, we designed ligands with desired signaling profiles.
252 ble to fabricating particulate drug carriers with desired size and shape.
253 to produce liquid-metal-dealloyed structures with desired size and topologies.
254 sign of Experiments to achieve nanoparticles with desired size, polydispersity, loading efficiency, a
255 uidelines for producing surface nanodroplets with desired sizes by controlling the flow conditions.
256 ese efforts may help to better align success with desired societal values.
257 fficiently uncovered developmental enhancers with desired spatial and temporal expression patterns in
258 etal-semiconductor branched heterostructures with desired spatial configurations, i.e., twenty CdS (o
259  framework for selecting RNA-binding fingers with desired specifications.
260 t requires discovery of an antibody molecule with desired specificities and drug-like properties.
261 he engineering of highly active FAR proteins with desired specificities for the production of fatty a
262 trategies alone can be used to discover TCRs with desired specificities.
263                          Therapeutic T cells with desired specificity can be engineered by introducin
264 resent a novel platform for creating ligands with desired specificity, and they offer many potentiall
265 for synthesizing simple glycosylsphingosines with desired sphingosine lengths (d18:1 or d20:1) from i
266 ci C-H cyclization to forge the C20-C22 bond with desired stereochemistry at C20.
267 t success in designing Ca2+-binding proteins with desired structural and functional properties opens
268 s the growth of high quality epitaxial films with desired structural and physical properties.
269 hesis of processable nanostructured polymers with desired structural integrity.
270 In this paper, a nano-magnetic Heusler phase with desired structure parameters was successfully obtai
271 r the controlled synthesis of nanostructures with desired structures and crystallinity.
272 ances of obtaining supramolecular frameworks with desired structures and properties.
273 nal design and guided discovery of chemicals with desired structures and properties.
274 e predictive synthesis of metal nanocrystals with desired structures relies on the precise control of
275 ionship study of MDRR agents, some compounds with desired substructural features and activity were id
276 ii) modification of the hydrophilic surfaces with desired sugars.
277              The synthesis of pure delta-MoN with desired superconducting properties usually requires
278 the design of two-dimensional (2D) materials with desired superstructures.
279 down design of complex protein nanomaterials with desired system properties and demonstrates the powe
280 ular control networks to infer perturbations with desired systems-level outcomes.
281 d N-alkylaminooxy groups enables conjugation with desired target molecules via established chemoselec
282 n process for producing pea protein isolates with desired techno-functional properties for meat analo
283 ed parametric space for fabricating surfaces with desired temperature-dependent wettability.
284 lable wound dressings that can deliver drugs with desired temporal patterns.
285 herapies using IgEs must balance Ag affinity with desired therapeutic effect.
286                           Design of proteins with desired thermal properties is important for scienti
287  for manipulating and protecting the photons with desired time-reversal symmetry.
288 ly and efficiently discovering metamaterials with desired topological state.
289 ed complex fluids or living polymer networks-with desired topologies.
290 uccessful example of rational design of MOFs with desired topology, but also provides a strategy for
291 ul implementation of rational design of MOFs with desired topology, but also provides a systematic wa
292 huffling can direct the evolution of viruses with desired traits.
293 c approaches towards designing endosymbioses with desired traits.
294  context effects, design sigma(70) promoters with desired transcription rates, and identify undesired
295 prospective isolation of cell subpopulations with desired transcriptional profiles.
296 lowed a rapid generation of multiple vectors with desired transgenes inserted in the deleted ICP6 loc
297 ogrammable scaffold, which can be prescribed with desired valence modes and affinity types.
298 nally, we show our model generates molecules with desired values of specified properties while mainta
299 p PIMs can transform forward SAWs into waves with desired wavefronts and energy patterns, such as SAW
300 s to accelerate the development of cultivars with desired yield potential, quality, and enhanced adap

 
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