ライフサイエンスコーパス: wobble base pair

1 n interacts with N7 of the cleavage site G.U wobble base pair.

2 state using a steric filter fashioned from a wobble base pair.

3 d duplex at an A-U base pair adjacent to the wobble base pair.

4 NMR data and modeling indicated a T(a).T(d) wobble base pair.

5 n both sides by cis Watson-Crick G/C and G/U wobble base pairs.

6 5'-U-U-3'/3'-G-G-5' non-symmetric tandem GxU wobble base pairs.

7 rmediate that involves DNA-base flipping and wobble base-pairs.

8 oaching that of its natural analogue, a G-T (wobble) base pair.

9 tion of miRNA base pairing or by creation of wobble base pairing.

10 on or by an artificial tRNA not dependent on wobble base-pairing.

11 ribozymes suggest that a pair of tandem G:U wobble base pairs adjacent to the reactive center consti

12 containing a bulged nucleotide adjacent to a wobble base pair also was primarily affected by non-near

13 The control duplex contained a G-U wobble base pair and also a G-A mismatched base pair.

14 Urd was substituted in one duplex at the G-U wobble base pair and in the second duplex at an A-U base

15 other hand, recognizes the TG mismatch as a wobble base pair and penetrates the DNA with three aroma

16 These sites contain a G-U wobble base-pair and a downstream uridine which is cleav

17 bove the average value and those between the wobble base-pairs and the flanking Watson-Crick base-pai

18 one containing a central G-T mismatched or "wobble" base pair, and one in which the thymine in this

19 er, interactions between adjacent codons and wobble base pairing are key.

20 ues for five terminal mismatches adjacent to wobble base pairs are also reported.

21 Adjacent GxU wobble base pairs are frequently found in rRNA.

22 crystallographic studies showing that tandem wobble base pairs are good binding sites for metal hexaa

23 ly occurring RNA hairpin sequences closed by wobble base pairs are reported.

24 G.U wobble base pairs are the most common and highly conserv

25 Guanine-uracil (G.U) wobble base-pairs are a detrimental lesion in DNA.

26 Previous investigations have shown that such wobble base-pairs are more prone to base-opening than th

27 he templating base, Poliota accommodates the wobble base pair better than the Watson-Crick base pair.

28 The former is most likely due to wobble base pairing between ClU and G, which may be more

29 side chain plays a pivotal role in excluding wobble base pairs between template pyrimidines and purin

30 n an accurate but inefficient manner with a "wobble" base pairing between C and O(6)-MeG.

31 cted that the free G-N2 amino group in a T:G wobble base pair can form two individual hydrogen bonds

32 The wobble base pairs contribute to the catalytic rate enhan

33 he ribozyme and the data here show that this wobble base pair destabilizes neighboring base pairs on

34 ycetes, the new tRNA circumvents inefficient wobble base-pairing during translation.

35 plets, which dominate bystander editing, G*U wobble base pairs effectively mitigate off-target events

36 ostatic potential at the major groove of G.U wobble base pairs embedded in RNA helices, suitable for

37 The G.U wobble base pair formed between a (15)N-labeled strand a

38 nces of the type GGXANmAYCC, where XY is the wobble base pair, GU or UG, and the underlined loop sequ

39 e modified base pair in the structure adopts wobble base pairing (hydrogen bonds between [POB]dG(N1)

40 econciled by possible tautomerization of the wobble base pair in mRNA-tRNA.

41 e reaction pathway and the significance of a wobble base pair in promoting the robustness of the acti

42 laRS) has depended predominantly on a single wobble base pair in the acceptor stem, G3*U70, mainly on

43 reases the stability of duplexes closed with wobble base pairs in an idiosyncratic manner.

44 ructure and the importance of two tandem G:U wobble base pairs in the template domain were studied by

45 The G.U wobble base-pair in the acceptor helix of Escherichia co

46 The G.U wobble base-pair in the acceptor helix of Escherichia co

47 a G.C replacement were reversed by a distal wobble base-pair in the anticodon helix.

48 However, G:U wobble base-pairing in this region interferes with activ

49 d, to a lesser extent, guanine residues from wobble base-pairs in hairpin stems.

50 ed 5ns molecular dynamics simulations on G.U wobble base-pairs in two different sequence contexts, TG

51 The helical distortions and wobble base pairing induced by the covalent binding of P

52 ults establish a new paradigm of inefficient wobble base-pairing involving GAU codons as an evolved s

53 pseudoknot sequence and found that a single wobble base pair is critical for function.

54 Importantly, the mcm(5)s(2)U(34).G(3) wobble base pair is in the Watson-Crick geometry, requir

55 G.U wobble base pairing is tolerated as a match for both RNA

56 at the negativity at the major groove of G.U wobble base pairs is determined by the combined effect o

57 n is bound in the major groove of the tandem wobble base pairs, is precisely positioned by the ribozy

58 spite of the presence of two adjacent G x U wobble base-pairs located at the center of the helix.

59 nt for elongation and that it is the U50.G64 wobble base pair, located at the same position in the TP

60 mately 1.5 kcal/mol and the d(G x T) reverse wobble base-pair more stable by approximately 0.5 kcal/m

61 2 genome excision leads to the disruption of wobble base pairing of SsrA due to site-specific recombi

62 air (on the guanine containing strand) and a wobble base pair (on the strand containing the difluorot

63 polymerase active site and the asymmetry of wobble base pairs, provides a plausible explanation for

64 ent upon the position and orientation of the wobble base pair relative the bulged nucleotide.

65 RO-seq reveals that thermodynamically stable wobble base pair (rG*dT) and free binding energy strongl

66 xes containing symmetrical tandem GxU or GxT wobble base pairs show that nearest-neighbor sequence de

67 om A-form helix occur where the guanine of a wobble base pair stacks over a purine from the opposite

68 -thymine mispairs may be associated with its wobble base pair structure.

69 Proton NMR suggests that wobble base pairing takes place between the 3'-T of the

70 Incorporation of 6MI yields wobble base-pairs that open more readily than their guan

71 ure, including a protonated adenine-cytosine wobble base-pair, that positions the cytosine base 5' to

72 or both of the bulge nearest neighbors was a wobble base pair, the free energy increment for insertio

73 In this wobble base pair, the G forms two hydrogen bonds with U

74 Mutation of the U50.G64 wobble base pair to C50:G64 or U50:A64 base pairs increa

75 translation speed including mRNA structure, wobble base pairing, tripeptide motifs, positively charg

76 ingly, when combinations of Watson-Crick (or wobble) base pairs were introduced in these positions, c

77 However, the wobble base pairing, where T pairs with G instead of A,

78 However, the wobble base pairs, where U in RNA (or T in DNA) pairs wi

79 Combining wobble base pairing with a circularized format of the CL

80 d melting temperature for duplexes closed by wobble base pairs with 3' single or double-nucleotide ov