ライフサイエンスコーパス: wound

1 ducing even minor levels of aggression (i.e. wounding).

2 ices, their debit, and the dimensions of the wound.

3 he spillage of intestinal effluvium from the wound.

4 um chloride in the immediate vicinity of the wound.

5 in, but have been suggested to accumulate in wounds.

6 e healing and is a characteristic of chronic wounds.

7 ed cell division and expansion to regenerate wounds.

8 inflammation and impaired healing in chronic wounds.

9 ics demonstrates accelerated healing of skin wounds.

10 toin (PHT) treatment of experimental palatal wounds.

11 d to infect full-thickness porcine cutaneous wounds.

12 es in chronically UV-exposed skin or chronic wounds.

13 able human cells present at the site of skin wounds.

14 giogenesis and expedites healing in diabetic wounds.

15 generate ECM-producing myofibroblasts within wounds.

16 s also found to infiltrate human skin during wounding.

17 gly reduced rosette growth in the absence of wounding.

18 th an initial lag in recruitment early after wounding.

19 llular matrix (ECM) formation by 3 days post-wounding.

20 ophages, and epithelial cells in response to wounding.

21 t the typical mammal displays in response to wounding.

22 Neutrophil recruitment is delayed in early wounds (12 hours and day 1), whereas late wounds (day 7)

23 rapy treatment [EE]) group (n = 26), palatal wounds, after FGG harvest, received application of micro

24 n the control (sham) group (n = 27), palatal wounds, after free gingival grafts (FGG) harvest, receiv

25 lus end-binding protein EB1/EBP-2 around the wound and actin ring formation, dependent on ARP2/3 bran

26 t previous instrumental signs of penetrating wound and complete visual restoration after surgery.

27 m flies, C. macellaria, that invade necrotic wound and feed on dead tissue.

28 RNA sequencing analysis of 6,154 cells from wounded and unwounded mouse skin revealed that MCS-01 pr

29 Perpetual cycles of wounding and healing drive fibrosis in DDEB and RDEB, as

30 icated in the recovery from diverse types of wounding and organ loss.

31 mucosal repair after biopsy-induced colonic wounding and recovery from dextran sulfate sodium-induce

32 Abiotic and biotic factors cause plant wounding and trigger complex short- and long-term respon

33 C subset that rapidly infiltrates human skin wounds and comprises a major DC population.

34 ates the angiogenic process in normal dermal wounds and thereby delays healing, whereas the stimulati

35 rimary cultures were established, monolayers wounded, and repair assessed (+/-) azithromycin (1 ug/mL

36 ificant increases in granulocytes in chronic wounds, and we show that patients with the junctional fo

37 eter wound (posterior) and one 4 mm diameter wound (anterior), each 1-1.5 mm deep, were created on bo

38 As in wounds, arachidonic acid rapidly attracted leukocytes th

39 thelialization and stromal remodeling of the wounded area without the need for cadeveric donor cornea

40 oth cancer and wound healing and discuss how wounding, as in biopsy and surgery, might positively or

41 inflicted by insect herbivory or mechanical wounding at ET resulted in COI1-dependent stomatal closu

42 ls are lower in chronic ulcers than in acute wounds at the proliferative phase.

43 rompted researchers to re-examine the normal wound bed physiology, resulting in new approaches to MSC

44 rative capacity of resident cells within the wound bed to overcome stalled wound healing.

45 R/SFRP4 and CD31 in the regenerated diabetic wound bed with TWIST1 overexpression or silencing (piLen

46 Compared with that of DeltasarA infection, wound biofilm burden was significantly higher in respons

47 an established preclinical porcine model of wound biofilm infection.

48 cluding acute irradiation injury and ectopic wound biopsies.

49 Wounds, body weights, food consumption, nest scores, suc

50 y expressed in normal skin and increase post-wounding but are completely absent in TSG-6-null mice.

51 ntered in bacterial infection, inflammation, wounds, cardiovascular defects and cancer.

52 Appropriate wound care is also essential.

53 Wound care professionals rely heavily on images and imag

54 a steadfast but time-consuming component of wound care with limited technical advancements to date.

55 pulate this typically avascular region after wounding closely associate with this MAGP1-rich matrix.

56 and Tolvaptan, or V2R gene silencing reduced wound closure and cell viability of 786-O and Caki-1 hum

57 esis in the wound tissues results in delayed wound closure and healing.

58 TSG-6 plays an important role in regulating wound closure and inflammation during cutaneous wound re

59 We investigated how loss of TSG-6 affects wound closure and skin inflammation.

60 TSG-6-null wounds rescues both the delay in wound closure and the aberrant neutrophil phenotype.

61 0 from no suture group (nSG) showed complete wound closure at day 14 (P >0.05) and at 30 days, comple

62 rmis is decreased in mouse models of delayed wound closure intended to mimic old age, obesity, and al

63 Wound closure rates are significantly delayed in TSG-6-n

64 ng model, i.p. MV administration accelerated wound closure through recruitment of PD-L1-expressing my

65 tial advantages over sutures and staples for wound closure, hemostasis, and integration of implantabl

66 0.1%, while the cooked honey had incomplete wound closure, the vacuum-treated honey trended towards

67 vacuum-treated honey trended towards faster wound closure.

68 significantly more cells infiltrating their wounds compared with patients with recessive dystrophic

69 Wound complication was present in 27.3% of patients, wit

70 4-6.35), biologic mesh (3.1, 1.67-5.75), and wound complications (3.01, 1.69-5.39) were predictors of

71 significantly reduced risk for perioperative wound complications (Odds Ratio 0.400 [95% confidence in

72 d models were used to identify predictors of wound complications and hernia recurrence, respectively.

73 posite of surgical-site infections and other wound complications, and adverse skin reactions.

74 Secondary outcomes included other wound complications, composite of surgical-site infectio

75 s requiring biologic mesh were predictors of wound complications, whereas recurrent hernia repair (2.

76 llergic contact dermatitis, and incidence of wound complications.

77 omentoplasty for the prevention of perineal wound complications.

78 Surgical wound cultures and resistance data were obtained within

79 ly wounds (12 hours and day 1), whereas late wounds (day 7) show elevated neutrophil accumulation.

80 matoma, seroma, surgical site infection, and wound dehiscence), abdominal eventration, and hernia rec

81 ndicates that iNPWT also reduces the risk of wound dehiscence, skin necrosis, and seroma.

82 vidence suggests that iNPWT may also prevent wound dehiscence, skin necrosis, seroma, and hematoma.

83 ted protein kinases (MAPKs) MPK3 and MPK6 by wounding depends on the upstream MAPK kinases MKK4 and M

84 During S phase, Hmo1 protects under-wound DNA from Top2, while Top2 confines Pol II and Top1

85 f Enterococcus, which was also cultured from wound drainage.

86 ical incision (n = 816), or receive standard wound dressing (n = 808).

87 candidates for controlled drug release based wound dressing applications.

88 indicated that the prepared mat is a proper wound dressing for DFU management and treatment.

89 n 6.68% (50 of 749 patients) of the standard wound dressing group (odds ratio, 0.87 [95% CI, 0.57 to

90 s 13.2% [78 of 590 patients] in the standard wound dressing group; odds ratio, 0.84 [95% CI, 0.59 to

91 egative pressure over the wound, vs standard wound dressing not involving negative pressure (n = 763)

92 Here we describe the use of discarded wound dressings as a novel, cost effective, accessible,

93 om textiles to composites, and waveguides to wound dressings.

94 mulation of podoplanin-positive cells at the wound edge.

95 In this study, we show that in human wound-edge keratinocytes, the expressions of microRNA (m

96 e three-dimensional collagen architecture of wounded embryonic corneas, whilst identifying temporal a

97 expertise can lead to improper diagnosis of wound etiology and inaccurate wound management and docum

98 Female C57BL/6J mice underwent dorsal wounding following an established splinted excisional sk

99 tes is pathogenic and contributes to chronic wound formation.

100 to perform a floating ostomy to isolate the wound from the debit enteric.

101 jury cannot be considered recovered when the wounds have healed; instead, burn injury leads to long-t

102 ll as healthy volunteers to study effects on wound healing (NCT04045405; NCT03603431).

103 l characteristics that might reproduce pASCs wound healing ability.

104 persecreting hMSC lines as short-term, local wound healing agents with superior therapeutic efficacy

105 reservoir of bioactive molecules to support wound healing and bone regeneration.

106 Sustained cell migration is essential for wound healing and cancer metastasis.

107 ectrotherapy protocol may accelerate palatal wound healing and decrease patient discomfort after FGG

108 allmarks that might apply to both cancer and wound healing and discuss how wounding, as in biopsy and

109 tory cells, which are active participants in wound healing and fibrogenic processes.

110 r matrix protein that has important roles in wound healing and fibrosis.

111 d, in so doing, to promote barrier function, wound healing and hair growth, while limiting cancer dev

112 ion of ribosomal proteins, and initiation of wound healing and humoral immune responses.

113 epithelial homeostasis, tissue regeneration, wound healing and immune modulation.

114 ial role in organ development and repair, in wound healing and in numerous pathological processes suc

115 s learned from the significant literature on wound healing and macrophage response to implanted bioma

116 Wound healing and Matrigel invasion assay, sphere format

117 Besides applications to wound healing and metastatic cancer, these studies are r

118 significantly reduce both corneal epithelial wound healing and nerve density in diabetic mice.

119 ways underlying angiogenesis, fertilization, wound healing and regeneration.

120 ained popularity in the field of periodontal wound healing and regeneration.

121 w of the angiogenic process during cutaneous wound healing and the regulatory roles played by catecho

122 d drug/cell delivery, thrombus ablation, and wound healing are reviewed from these viewpoints.

123 r is introduced for analyzing a standardized wound healing assay by observing cell growth and quantif

124 xperiments of cell proliferation, apoptosis, wound healing assay, as well as reverse-phase protein ar

125 Using an in vitro wound healing assay, cell migration was evaluated 2, 4,

126 is evaluated on sparse real-world data from wound healing assays with varying initial cell densities

127 tissue and its up-regulation is required for wound healing but is also involved in fibrosis.

128 After surgery or traumatic injury, corneal wound healing can cause a scarring response that stiffen

129 The wound healing efficacy of the fabricated dressings was e

130 of reducing bacterial load and accelerating wound healing in an excisional wound model.

131 egulatory function of WDR26 in FPR1-mediated wound healing in intestinal epithelial cells.

132 In an excisional wound healing model, i.p. MV administration accelerated

133 Using an endoscopic biopsy-based wound healing model, we report that RvE1 is locally prod

134 ype 1 and 2 diabetic full-thickness splinted wound healing murine model enhanced the microcirculatory

135 ion of this mechanism in studies in vivo, in wound healing or angiogenesis, in which fibrin is contra

136 ective tissue shares features with mammalian wound healing or fibrosis.

137 and non-sutured sites display similar early wound healing outcomes and patient-reported outcomes.

138 to chemoattraction of cells critical to the wound healing process, eCRT induces abundant neo-dermal

139 ted for their potential to contribute to the wound healing process.

140 Reduced wound healing ratios and nerve densities were not fully

141 scaffolds have great potential for improving wound healing treatments by providing controlled drug de

142 may help to uncover and develop fat-related wound healing treatments.

143 wounds were created using an Algerbrush, and wound healing was monitored over time.

144 ved in the LCD1 patients, corneal epithelial wound healing was significantly delayed in TGFBI-R124C m

145 oteins associated with skin blood supply and wound healing were altered.

146 eview provides a brief overview of cutaneous wound healing with discussion on how extracellular matri

147 ferences were found for complicated perineal wound healing within 30 days (RR 1.30; 95% CI 0.92-1.82)

148 sed two pathway-focused RT-PCR gene arrays ("wound healing" and "neurogenesis") to evaluate tissue sa

149 iseases (e.g., cancer, heart attack, stroke, wound healing).

150 nning, fragility, wrinkles, laxity, impaired wound healing, and a microenvironment conducive to cance

151 ding on the involvement of adipose tissue in wound healing, and may help to uncover and develop fat-r

152 for normal processes such as development and wound healing, but can go awry, as in oncogenesis and fi

153 gh cell plasticity underlying embryogenesis, wound healing, cancer metastasis and drug resistance.

154 fferent roles of fibroblasts in ECM biology, wound healing, diseases, and aging.

155 Striking similarities between wound healing, epimorphic regeneration and the progressi

156 gene expression in three settings: in vitro wound healing, live lymph node sections and a live tumor

157 rom bone marrow cells is required for normal wound healing, revealing a physiological role for this g

158 proliferation, colony formation, migration, wound healing, tumor growth, and lung metastasis.

159 and it is an essential step during cutaneous wound healing, which supports cells at the wound site wi

160 lteration resembling the remodeling phase of wound healing, with increased matrix metalloproteinase e

161 EMT is crucial to embryonic development and wound healing.

162 ion, cell dispersion, neuronal survival, and wound healing.

163 ined in the animal studies indicate a proper wound healing.

164 ers that coalesce into clots which assist in wound healing.

165 tiation and phenotypic changes in cancer and wound healing.

166 could be reactivated and play roles in adult wound healing.

167 s medically and/or electronically facilitate wound healing.

168 es of microcurrent electrotherapy on palatal wound healing.

169 /f)Lyz2(Cre+)) resulted in improved diabetic wound healing.

170 ion of inflammation, cell proliferation, and wound healing.

171 in vitro slows keratinocyte migration during wound healing.

172 L28 and IL-6 levels associated with improved wound healing.

173 the transcriptional landscape that influence wound healing.

174 glycoprotein 1 (LRG1) in normal and diabetic wound healing.

175 actor-beta (TGFbeta) play a critical role in wound healing.

176 lls within the wound bed to overcome stalled wound healing.

177 MoS(2) on integrins, cellular migration, and wound healing.

178 with the NPWT system in order to accelerate wound healing.

179 tial changes in collagen organization during wound healing.

180 FU, indicating a potential important role in wound healing.

181 the immune system is inextricably linked to wound healing/remodeling in the ischemically injured hea

182 stem cells (ASCs) have potential to improve wound healing; however, their equivalents from domestic

183 epared derivatives showed promising in vitro wound-healing activity.

184 We report on in vitro wound-healing and cell-growth studies under the influenc

185 l wounding in Hydra, suggesting that Hydra's wound-healing and self-organization capabilities may emp

186 The wound-healing assay demonstrated that, at concentrations

187 Subsequent in vitro wound-healing assays also confirmed that M2 and M13 acce

188 starting point for the development of novel wound-healing promoters.

189 y is thus due to an acute inflammatory-based wound-healing response that rejuvenates the infarcted ar

190 W amplitude, resulting in an increase of the wound-healing speed of up to 135 +/- 85% as compared to

191 Wound-healing was also impaired in PSW compared to contr

192 is able to differentiate chronic from acute wounds, identifying significant increases in granulocyte

193 de the first evidence that following corneal wounding immune cells are activated to travel along zonu

194 lated from a normally sterile site or from a wound in patients with necrotizing fasciitis or streptoc

195 ination of wound responses after laser-based wounding in Arabidopsis root.

196 tion in the endoderm also arise during local wounding in Hydra, suggesting that Hydra's wound-healing

197 critical for leukocyte recruitment following wounding in larval zebrafish,(6-9) where H(2)O(2) activa

198 Large skin wounds in adult mice can heal by regenerating new hair f

199 aphylococcus aureus infected delayed healing wounds in rats with DM2.

200 regarding diagnostics and management of burn wounds in veterinary patients and current knowledge is e

201 Wounding increased total free (288.1%) and bound (407.6%

202 n screw configuration, further increased the wound-induced accumulation of total free (296.6%) and bo

203 This localized auxin increase balances wound-induced cell expansion and restorative division ra

204 m cell persistence after injury, implicating wound-induced ERK activity in this response.

205 ells in the notochord bead and for promoting wound-induced proliferation required for efficient regen

206 ffering, the amelioration of osmotic stress, wounding-induced sieve tube occlusion, and possibly loca

207 lenged in vivo with the polybacterial bovine wound infection 'digital dermatitis', Zn/Cu-shellac adhe

208 ponse syndrome, sepsis, acute kidney injury, wound infection (superficial and deep), rate of intraope

209 yse both host and pathogen biomarkers during wound infection in near real-time.

210 ls, (ii) intradermal infection models, (iii) wound infection models, and (iv) epicutaneous infection

211 myositis and a clinically relevant S. aureus wound infection murine model.

212 opathy, cerebral radionecrosis) and surgery (wound infections, flap necrosis, fistulas,...).

213 ted because three patients developed delayed wound infections.

214 9a/b and miR-20a being crucial regulators of wound inflammation, the lack thereof may contribute to s

215 Transfer of cDC2s isolated from late-stage wounds into healthy skin was sufficient to induce itchin

216 Finally, in simulations of wound invasion, efficient collective migration is achiev

217 ultiple logistic regression model the factor wound irrigation with polyhexanide [odds ratio (OR) 0.44

218 xisting studies suggest that pNPWT on closed wounds is protective against the occurrence of SSI in ab

219 r diagnosis of wound etiology and inaccurate wound management and documentation.

220 Digital education on chronic wound management appears to be less effective than blend

221 MSCs face a variety of challenges within the wound micro-environment that curtail their survival afte

222 rotein-rich environment of a purulent animal wound model infected with drug-resistant bacteria.

223 restore saliva flow rate in a salivary gland wound model of C57BL/6 mice.

224 accelerating wound healing in an excisional wound model.

225 wing an established splinted excisional skin wounding model.

226 stration of Myr-CBD7 peptide on mouse dermal wounds not only blocked CCR10-eNOS interaction, but also

227 ver a period of 2 weeks following mechanical wounding of the cultures and the responses were compared

228 This suggests that ice-nucleation-induced wounding of the wheat leaf provides additional openings

229 al regulators, CCL2 levels were increased in wounds of diabetic mice, and subsequent experiments show

230 the eye and/or adnexa, open globes and open wounds of ocular adnexa, diplopia, superficial corneal a

231 Wounds on one randomly chosen side received 10% phenytoi

232 owed us to gain mechanistic insight into the wound perception and coordination of wound responses aft

233 Intravital biosensor imaging showed that wound peroxide and arachidonic acid converged on half-mi

234 ogenous FXIII was topically applied into the wound pocket of rats, eleven adhesive failures occurred

235 One 6 mm diameter wound (posterior) and one 4 mm diameter wound (anterior)

236 ng seedlings and allowing time to heal graft wounds prior to spring transplanting or double cropping

237 meters were analyzed inside tooth-extraction wound: proportion of newly formed bone (bone healing/BH)

238 ice and/or biliary stent only, regardless of wound protector use (odds ratio = 0.69-0.70, P < 0.001).

239 shing a simple wounding system, we show that wounding provokes a reorganisation of plasma membrane su

240 received 10% phenytoin USP and contralateral wounds received carrier alone.

241 lso confirmed that M2 and M13 accelerate the wound recovery process of Caco-2 cells at the concentrat

242 h diffusion of mesenchymal stem cells to the wounded region and their subsequent differentiation.

243 and connected component labelling to segment wound regions from natural images.

244 we show that Pavarotti also functions during wound repair and confirm that while Pavarotti, Tumblewee

245 rly relevant in biological processes such as wound repair and embryonic development where cell spread

246 Resolution of intestinal inflammation and wound repair are active processes that mediate epithelia

247 gator tails identifies a distinct pattern of wound repair in mammals while exhibiting features in com

248 Efficient wound repair is critical to reestablish the mucosal barr

249 We show that WDR26-mediated inhibition of wound repair is mediated through the inhibition of Rac f

250 ctors inducing greater bone regeneration and wound repair than wild-type growth factors, as well as r

251 ellular matrix during embryonic development, wound repair, and tumor invasion.

252 nd closure and inflammation during cutaneous wound repair.

253 he miR-17~92 cluster, are upregulated during wound repair.

254 ration in plants and distinguish between the wound-repair ability of the tissue and its formation dur

255 Reintroduction of TSG-6 into TSG-6-null wounds rescues both the delay in wound closure and the a

256 and (iv) in vivo temporal monitoring of the wound response in living zebrafish embryos.

257 Wound-response plant growth restriction requires the syn

258 nto the wound perception and coordination of wound responses after laser-based wounding in Arabidopsi

259 that chronic S. aureus biofilm infection in wounds results in impaired granulation tissue collagen l

260 Our observations suggest that the wound signaling involves the sensing of collapse of dama

261 nvolved in physiological processes including wound signaling, stomatal regulation, and pollen tube gr

262 solic Ca(2+) increases to propagate systemic wound signaling.

263 s wound healing, which supports cells at the wound site with nutrition and oxygen.

264 ent of PD-L1-expressing myeloid cells to the wound site.

265 integrated those findings with datasets from wounded skin and our transcriptomic data on cuSCC using

266 Wounded skin models were inoculated with bacteria and le

267 s in common between acutely UV-exposed skin, wounded skin, and cuSCC tumors, might enable us to ident

268 onic composition of their surroundings after wounding, specifically the concentration of sodium chlor

269 In the fly, wounding stimulates the rapid production of hydrogen per

270 present study, the sequential application of wounding stress and extrusion on total free and bound ph

271 Postharvest wounding stress in carrots induces the accumulation of p

272 in "small steps" of 5 mm, in an approximate wound-suture ratio of 1:10.

273 Here, by establishing a simple wounding system, we show that wounding provokes a reorga

274 Linear corneal wounds that traversed the epithelial layer, Bowman's lay

275 Incisional negative pressure wound therapy (n = 785), which involved a specialized dr

276 g 3D printing for use with negative pressure wound therapy (NPWT) in the management of enteroatmosphe

277 atients) of the incisional negative pressure wound therapy group and in 6.68% (50 of 749 patients) of

278 atients] in the incisional negative pressure wound therapy group vs 13.2% [78 of 590 patients] in the

279 port the use of incisional negative pressure wound therapy in this setting, although the event rate a

280 ither undergo prophylactic negative pressure wound therapy, with application of the negative pressure

281 ivated Draper then guides macrophages to the wound through the detection of an as-yet unidentified ch

282 ation tissue collagen leading to compromised wound tissue biomechanics.

283 gh amounts of interleukin 31 (IL-31) in skin wound tissue during the peak of itch responses.

284 induce neovascularization-mediated diabetic wound tissue regeneration.

285 rocirculatory blood flow and accelerated the wound tissue regeneration.

286 Impaired angiogenesis in the wound tissues results in delayed wound closure and heali

287 addition, this fast module does not control wound-triggered JA accumulation in Arabidopsis (Arabidop

288 Here we report that tissue and cellular wounding triggers rapid and reversible mitochondrial fra

289 controlled, sterile clinical settings where wounds urgently require protection from environmental an

290 m transcriptional responses in the immediate wound vicinity.

291 ng used to create negative pressure over the wound, vs standard wound dressing not involving negative

292 Wounding was applied by shredding carrots and storing th

293 Corneal epithelial wounds were created using an Algerbrush, and wound heali

294 The wounds were infected with methicillin-resistant Staphylo

295 Posterior wounds were left undisturbed to clinically evaluate heal

296 y, mice were euthanized and pelted to assess wounding with the pelt aggression lesion scale (PALS).

297 skin to regenerate instead of only repairing wounds with a scar, without perturbing development and h

298 paired neutrophil directed migration to tail wounds with an initial lag in recruitment early after wo

299 Greater Mpigi region used for infections and wounds, with 13 out of 16 species tested being validated

300 were formed in situ over stromal keratectomy wounds without sutures showed that they supported multi-