ライフサイエンスコーパス: wounding

1 ducing even minor levels of aggression (i.e. wounding).

2 t the typical mammal displays in response to wounding.

3 was performed on days 3, 7, 10, and 14 after wounding.

4 a similar manner in both genotypes following wounding.

5 growth and prevented new HF formation after wounding.

6 n was related to the intensity of mechanical wounding.

7 s also found to infiltrate human skin during wounding.

8 investigate mechanisms of calcium entry upon wounding.

9 ack by pests and pathogens or from damage by wounding.

10 read to neighboring cells, within seconds of wounding.

11 ficiency in restoring the skin barrier after wounding.

12 to hair loss and impairs regeneration after wounding.

13 such as flooding, nutrient deprivation, and wounding.

14 37 and dsRNA, a condition that mimics normal wounding.

15 ise only asynchronously with growth or after wounding.

16 g cells in the early phase within 24 h after wounding.

17 erentially expressed in response to parental wounding.

18 asite types but is not induced after sterile wounding.

19 inally resulting in immediate lethality upon wounding.

20 ls resembled the syncytia caused by physical wounding.

21 the regeneration of the new epidermis after wounding.

22 oduli of living cells during migration after wounding.

23 a robust LUC activity solely in response to wounding.

24 ial Ca(2+) uptake and mtROS production after wounding.

25 red for the response to fungal infection and wounding.

26 1A) has been implicated in fibrosis and skin wounding.

27 oth the nucleus and cytoplasm at 1 day after wounding.

28 nucleus in the dermis at 2 and 7 days after wounding.

29 erate epidermal covering following cutaneous wounding.

30 th an initial lag in recruitment early after wounding.

31 lso mainly enhanced by drought and little by wounding.

32 Arabidopsis thaliana subjected to mechanical wounding.

33 ferlin-containing vesicle behavior following wounding.

34 expression of genes involved in response to wounding.

35 ve movement of the epithelium in response to wounding.

36 but failed to accumulate JA or JA-Ile after wounding.

37 mes and release norepinephrine after scratch wounding.

38 es, 254 changed significantly in response to wounding.

39 RN1 increased the plant response to physical wounding.

40 ocyte-derived norepinephrine increased after wounding.

41 egeneration and early epidermal repair after wounding.

42 d in the corneal epithelium and stroma after wounding.

43 the interfollicular epidermis upon epidermal wounding.

44 = .04) in skin when measured 72 hours after wounding.

45 at precise times during the first week after wounding.

46 ing their inability to regenerate hair after wounding.

47 ate the in vivo role for IL-22 in acute skin wounding.

48 in's dermal compartment after full-thickness wounding.

49 ith time, maturing as early as 14 days after wounding.

50 tinopathy induced by high oxygen or by laser-wounding.

51 gly reduced rosette growth in the absence of wounding.

52 s, and accelerated neurite regeneration with wounding.

53 getative growth restriction after repetitive wounding.

54 tion during culm development or triggered by wounding.

55 OX3 and LOX4 control leaf growth rates after wounding.

56 g complex epithelial structures even without wounding.

57 ls and immune cells in the early phase after wounding.

58 (neutrophils) to the wound bed 24-48 h post-wounding.

59 rom Acomys and Mus musculus before and after wounding.

60 of the features of Ck1alpha reduction during wounding.

61 closure mostly completed by day seven after wounding.

62 ctivation as a response to tissue damage and wounding.

63 e wounded RHE (wRHE) in the first days after wounding.

64 ient mice failed to stimulate IL-1beta after wounding.

65 nerate de novo hair follicles following deep wounding.

66 llular matrix (ECM) formation by 3 days post-wounding.

67 he regulation of CCL2 and CCR2 after corneal wounding.

68 ted phenotype in skin keratinocytes prior to wounding.

69 on, oxidative stress, detergent exposure and wounding.

70 ophages, and epithelial cells in response to wounding.

71 egeneration of skin and hair follicles after wounding--a process known as wound-induced hair neogenes

72 Nucleotides released after scratch wounding activate purinergic receptors, leading to a dis

73 To date, nothing is known about how wounding activates DUOX.

74 Taken together, our results indicate that wounding alone activates the PO cascade in B. mori.

75 uced by real and mimicked herbivory, but not wounding alone.

76 ellipodia, focal adhesions, and repair after wounding, along with impaired H2O2 responses after expos

77 al kinase (JNK) signaling, which occurs upon wounding, also correlated with syncytium formation induc

78 o receive acute treatment (immediately after wounding and 24 hours later) with an aCT1 gel formulatio

79 Next, we treated RSRE::LUC plants with wounding and a range of rapidly stress-inducible hormone

80 In vitro wounding and collagen gel contraction assays were used t

81 nse to specific stresses and determined that wounding and drought differentially alter oxylipin profi

82 ocal microscopy, we showed that both aseptic wounding and Escherichia coli inoculation triggered macr

83 Both, wounding and exposure of 4T1 cells to SDF-1alpha not onl

84 Perpetual cycles of wounding and healing drive fibrosis in DDEB and RDEB, as

85 ally cleaved HCII forms were detected during wounding and in association with bacteria.

86 , preparing the body for situations in which wounding and infection may be more likely (social isolat

87 nces lymphangiogenesis following both dermal wounding and inflammatory challenge.

88 EGFR activation was maximal 15 minutes after wounding and localized in the migrating epithelial cells

89 lowground or toward damaged leaves following wounding and MeJA treatment to young leaves, suggesting

90 We found that upon wounding and methyl jasmonate treatments, MYB11 and ZML2

91 cultured epithelial cells was upregulated by wounding and neutrophil elastase.

92 icated in the recovery from diverse types of wounding and organ loss.

93 Airway epithelial responses to wounding and osmotic stress were assessed in primary air

94 Stimuli ranging from wounding and pathogen attack to the distribution of wate

95 n inactive form of JA that accumulates after wounding and pathogen attack, is unknown.

96 mucosal repair after biopsy-induced colonic wounding and recovery from dextran sulfate sodium-induce

97 s effect upon alveolar epithelial cell (AEC) wounding and repair remains poorly understood.

98 Blunted epidermal Ca(2+)(i) response to wounding and retarded wound healing were observed in the

99 arcomeric component, is strongly elevated by wounding and tissue injury.

100 Abiotic and biotic factors cause plant wounding and trigger complex short- and long-term respon

101 acellular space is triggered by insults like wounding and ultraviolet radiation, resulting in stimula

102 gular cycles of synchronous tissue shedding (wounding) and repair that occur during menstruation befo

103 many different signals including pathogens, wounding, and abiotic stresses.

104 antly among background strains of mice after wounding, and all correlated such that the highest Ptgds

105 ll molecule AMD 3100 abolished the effect of wounding, and decreased cell proliferation, collagen dep

106 Dorsal is activated on wounding, and Dif and Dorsal are required for the sustai

107 ion increased dramatically immediately after wounding, and down-regulation of transient receptor pote

108 vation in enterocytes following infection or wounding, and for ISC activation upon infection or deter

109 was dose-dependent, maintained by sequential wounding, and relative to distance.

110 cellular structure organization, response to wounding, and several immune-related terms.

111 se to challenges including oxidative stress, wounding, and shear stress.

112 ivated Tregs accumulated in skin early after wounding, and specific ablation of these cells resulted

113 scopy) and nuclear Atox1 are increased after wounding, and that wound healing with and without Cu tre

114 tal injury (such as UV exposure and physical wounding), apoptosis is an important mechanism regulatin

115 formation following JNK hyperactivation and wounding appeared to be direct disassembly of FA complex

116 ritically injured casualties within hours of wounding appears to be effective, with a minimal mortali

117 rabidopsis, AtCML37 is induced by mechanical wounding as well as by infestation with larvae of the ge

118 ML3 gene expression is promoted by wounding as well as by the phytohormone jasmonic acid an

119 oth cancer and wound healing and discuss how wounding, as in biopsy and surgery, might positively or

120 After wounding, Ash1l mutation leads to delayed re-epithlializ

121 are released from astrocytes in an in vitro wounding assay also induce COX-2 expression through a PL

122 Using a new tail-wounding assay to test the relationship between clot for

123 platform on which a reproducible electrical wounding assay was conducted to model RPE damage.

124 l substrate and restrained EC migration in a wounding assay.

125 e Sensing (ECIS) and reproducible electrical wounding assays to model and quantitatively study AMD.

126 inflicted by insect herbivory or mechanical wounding at ET resulted in COI1-dependent stomatal closu

127 eatment of the zone of injury at the time of wounding before scar formation.

128 y expressed in normal skin and increase post-wounding but are completely absent in TSG-6-null mice.

129 gulates induction of TGase2 expression after wounding but does not affect expression of the component

130 d cell migration over the denuded area after wounding but was rescued by increasing HuR levels.

131 educes angiogenesis in response to cutaneous wounding, but enhances lymphangiogenesis following both

132 cation is induced by external inputs such as wounding, but the molecular mechanisms that link this st

133 released from its cytoplasmic precursor upon wounding by a metacaspase that is activated by calcium i

134 l-specific T cells rapidly respond to tissue wounding by producing type 2 T helper cell (Th2) cytokin

135 servations indicate that cell mass lost upon wounding can be replaced by polyploidization instead of

136 1), nutrient deficiency (case study 2), and wounding (case study 3).

137 We show that skin wounding causes local production of mtROS superoxide at

138 te, salicylic acid, ultraviolet B light, and wounding, chosen on the basis of identified cis-regulato

139 pulate this typically avascular region after wounding closely associate with this MAGP1-rich matrix.

140 ic fruits and vegetables could be due to the wounding component of the biotic stress attributed to in

141 e induction of cellular migration by scratch-wounding confluent cell cultures, culturing under subcon

142 nation of bacteria, chronic inflammation and wounding cooperate to trigger skin cancer.

143 ted protein kinases (MAPKs) MPK3 and MPK6 by wounding depends on the upstream MAPK kinases MKK4 and M

144 Wounding downregulated B2AR, tyrosine hydroxylase, and p

145 recent study shows that, upon stretching or wounding, epithelia display a fast proliferative respons

146 t orchestrates plant defenses in response to wounding, feeding insects, or necrotrophic pathogens.

147 integrated into RSRE::LUC parent plant, with wounding, flg22, and freezing, established a differentia

148 which was highly upregulated in response to wounding followed by ethylene, methyl jasmonate and ABA

149 Female C57BL/6J mice underwent dorsal wounding following an established splinted excisional sk

150 TSG-6-null skin and increases further after wounding (from 12 hours to 7 days) before returning to b

151 As Arabidopsides are known to be induced by wounding, further experiments on wounded and non-wounded

152 ncytium formation, including that induced by wounding, genetic loss of FA proteins, or local JNK hype

153 Further, CsCCD4c was up-regulated by wounding, heat, and osmotic stress, suggesting an involv

154 n plants to those usually produced following wounding, herbivory and pathogen invasion.

155 Upon wounding, however, PKD1-deficient mice exhibited delayed

156 de the first evidence that following corneal wounding immune cells are activated to travel along zonu

157 the clade-C MAPKs MPK1/2/7, is activated by wounding in a MKK4/5-independent manner.

158 ination of wound responses after laser-based wounding in Arabidopsis root.

159 tem for measuring systemic responses to root wounding in Arabidopsis thaliana We found that root woun

160 mily members was markedly downregulated upon wounding in both young and aged mice, with an exception

161 glands in reconstituting the epidermis after wounding in humans.

162 tion in the endoderm also arise during local wounding in Hydra, suggesting that Hydra's wound-healing

163 critical for leukocyte recruitment following wounding in larval zebrafish,(6-9) where H(2)O(2) activa

164 as delayed at the 3(rd) and 7(th) days after wounding in mice that received EPA-rich oil when compare

165 t predicts new hair follicle formation after wounding in mice.

166 SD 4%) injuries but also allows for repeated wounding in microfluidic environments.

167 Following wounding in Mus the complement and coagulation cascades,

168 erlin-containing vesicles following cellular wounding in muscle cells and examine the role of microtu

169 and vesicle-organelle fusion in response to wounding in muscle cells.

170 a1 and beta3 were upregulated in response to wounding in NL corneal epithelial cells (CECs), whereas

171 Tissue regeneration upon wounding in plants highlights the developmental plastici

172 In an adult model of chronic wounding in zebrafish, we show that repeated wounding wi

173 Wounding increased total free (288.1%) and bound (407.6%

174 Our data show that skin wounding increases myeloid lineage-committed multipotent

175 Specifically, wounding induced both 12-OPDA and JA levels, whereas dro

176 Laser-wounding induced rapid recruitment of approximately 30 m

177 lso, caterpillar feeding, but not mechanical wounding, induced foliar RIP2 protein accumulation.

178 Silencing of Fos or of TGase2 aborts the wounding-induced mosquito killing of P. falciparum.

179 ffering, the amelioration of osmotic stress, wounding-induced sieve tube occlusion, and possibly loca

180 ormones abscisic and indole acetic acid, and wounding-induced up-regulation of the defence signalling

181 In conclusion, our study reveals that wounding induces a high degree of heterogeneity among fi

182 Membrane wounding induces dysferlin-containing vesicle-vesicle fu

183 Additionally, we found that acute wounding induces epithelial cell mmp9 expression and is

184 Wounding induces lysosome exocytosis and endocytosis of

185 nopoiesis, our results demonstrate that skin wounding induces Mo progenitor and Mo expansion independ

186 of this study was to determine whether skin wounding induces monocyte (Mo) expansion in bone marrow

187 Wounding induces the expression of VEFG, which may modul

188 results in epidermal inflammation, and skin wounding induces tumours.

189 upregulated coding genes mostly involved in wounding, inflammation and defense, whereas the downregu

190 Conversely, wounding inhibits BCR signaling and internalization by d

191 r, these results support the hypothesis that wounding inhibits P-type H(+)-ATPase activity, leading t

192 cated, e.g., 2D cell migration after scratch-wounding, invasion of cancer cells, and finally, myofibr

193 double-stranded RNA (dsRNA) released during wounding is both necessary and sufficient to stimulate W

194 atelet enhancement of lymphatic growth after wounding is dependent on the release of VEGFC, but not V

195 Our findings explain why wounding is linked to formation of ECM-rich scar tissue

196 n young skin, re-epithelialization following wounding is perturbed.

197 EFN secretion is commonly induced after wounding, likely owing to a jasmonic acid-induced cell w

198 Environmental challenges such as wounding, low temperature, oxidative states and pathogen

199 electrical signals, which can be induced by wounding, may also enable signalling over relatively lon

200 Data included demographics, wounding mechanism, injuries sustained, prehospital time

201 The lack of reproducible, high-throughput wounding methods has hindered single-cell wound repair s

202 mechanistic studies impossible with current wounding methods.

203 WST-1 proliferation and cell-wounding-migration assays were assessed in IEC-6 cells e

204 on and healing was also observed in a dermal wounding model with deletion of Mapk14.

205 wing an established splinted excisional skin wounding model.

206 After wounding, multiple cell types interact to form a fibrova

207 After wounding of an epithelium, the cells bordering the wound

208 Mechanical probe-induced micro-wounding of both endothelia and epithelia suggests that

209 Mechanical wounding of freshly-pruned canes drastically shortens th

210 ) fibroblasts is selectively increased after wounding of human skin.

211 In the present study, we found that wounding of rat ATII cells promoted increased associatio

212 ver a period of 2 weeks following mechanical wounding of the cultures and the responses were compared

213 Here, we show that laser wounding of the Drosophila embryo epidermis triggers an

214 Consequently, this needle-puncture wounding of the insect gut can be developed for screenin

215 The inevitable wounding of the roots caused by harvesting triggers an o

216 y abdominal inoculation coupled with aseptic wounding of the thorax.

217 This suggests that ice-nucleation-induced wounding of the wheat leaf provides additional openings

218 the present study, the effect of mechanical wounding on freshly-pruned canes was tested to increase

219 ains we could demonstrate that the effect of wounding on tumor growth and SDF-1alpha levels is host d

220 is genotypes that were damaged by mechanical wounding or by insects of various feeding guilds (pierci

221 mucosal repair after biopsy-induced colonic wounding or Dextran Sulfate Sodium (DSS)-induced mucosal

222 er several abiotic-stress conditions such as wounding or exposure to salinity, cadmium, and low tempe

223 Wounding or exposure to sphingomyelinase triggered endoc

224 that are generated in plants in response to wounding or flaming.

225 oes not support the concept of a significant wounding or immune response following biopsy in the abse

226 ns and also under multiple stresses, such as wounding or infection.

227 investigated in Norway spruce saplings after wounding or inoculation with the fungal pathogen Ceratoc

228 g the perception of an abiotic stress event, wounding or pathogen infection, from its initial site of

229 ed is even more acute after tissue damage by wounding or pathogenic infection.

230 g in Arabidopsis thaliana We found that root wounding or the application of glutamate to wounded root

231 Here we demonstrate that after wounding or ultraviolet type B irradiation, melanocyte s

232 cumulation of tuberonic acid (12OH-JA) after wounding originates partly through a sequential pathway

233 her more acute molecular responses to UV and wounding overlapped with molecular signatures of cuSCC.

234 se to biotic and abiotic influences, such as wounding, pathogen attack, and cold acclimation, but als

235 Here, through an 8-year study of wounding patterns, territorial behaviour, and agonistic

236 nvolved in plant stress responses, including wounding, perhaps to evoke plant defense.

237 ative clonal analysis reveal that, following wounding, progenitors divide more rapidly, but conserve

238 shing a simple wounding system, we show that wounding provokes a reorganisation of plasma membrane su

239 reys in the lakes is calculated by surveying wounding rates on lake trout (Salvelinus namaycush), and

240 Mechanical wounding reduced fibroblast aromatase activity but incre

241 ow these processes are coordinated following wounding remained unclear.

242 Restoring homeostasis after wounding requires the coordinated actions of epidermal a

243 nal signature reminiscent of a JNK-dependent wounding response, while mating-or injection of virgins

244 ycosylating, and acylating activities in the wounding response.

245 o lignin biosynthesis as part of its natural wounding response.

246 nelle functions, and is related to touch and wounding responses.

247 Wounding resulted in a decrease of preformed 12-oxo-phyt

248 Cutaneous wounding resulted in loss of epithelial marker E-cadheri

249 Corneal epithelial wounding resulted in significant delay in recovery of th

250 he cotyledon-to-root JA signal velocities on wounding, revealing two distinct phases of JA activity i

251 ed that Arabidopsides are highly abundant at wounding sites in both wild-type and fer mutant leaves.

252 onic composition of their surroundings after wounding, specifically the concentration of sodium chlor

253 In contrast, upon wounding, stem cell progeny from multiple compartments a

254 In the fly, wounding stimulates the rapid production of hydrogen per

255 , demonstrating their plasticity to adapt to wounding stimuli.

256 present study, the sequential application of wounding stress and extrusion on total free and bound ph

257 ruits can be triggered by the application of wounding stress in a distant tissue and this accumulatio

258 Postharvest wounding stress in carrots induces the accumulation of p

259 crop in field conditions, a preharvest leaf wounding stress was applied to study the production of p

260 under both pathogen infection and mechanical wounding stress.

261 In wounding studies, Wfdc1-null mice exhibited an elevated

262 However, little is known about how wounding, such as following surgery, biopsy collection o

263 onsive enhancers during development and upon wounding suggests cooperation with distinct TFs in diffe

264 Here, by establishing a simple wounding system, we show that wounding provokes a reorga

265 , salicylic acid, and gibberellic acid or by wounding, temperature, and light, factors known to affec

266 in the abdomen and additionally showed that wounding the cuticle of the abdomen results in decreased

267 In Caenorhabditis elegans, wounding the epidermis triggers an immune reaction and a

268 , modulates hair follicle regeneration after wounding the skin of adult mice.

269 inhibits intestinal epithelial repair after wounding, the mechanisms that control Stim1 expression r

270 Upon wounding, the number of epidermal and dermal monocytes a

271 After wounding, the P2Y2 receptor mRNA expression increased, a

272 urrounding tissue, and that after surgery or wounding, the resulting RI mismatch between the activate

273 Our work shows that, immediately after wounding, there was a dramatic cytoskeleton remodeling c

274 Following full thickness wounding, there was no migration of tdTomato-labeled cel

275 ssociation between the duration of time from wounding to arrival at Landstuhl Regional Medical Center

276 after cellular damage caused by pathogens or wounding to induce innate immunity by direct binding to

277 hinery that directs repair, we applied laser wounding to live mammalian myofibers and assessed transl

278 3 link the earliest events of mammalian skin wounding to regeneration and suggest potential therapeut

279 In diabetic mice, both pre- and post-wounding, topical MCS-01 application accelerated wound h

280 th the potential role of oxidative stress in wounding, treatment with purified LAAO decreased keratin

281 induced by drought, cold, abscisic acid, and wounding treatments.

282 Upon wounding, Tregs induce expression of the epidermal growt

283 Wounding triggered mitochondrial fragmentation is indepe

284 In adult mammals, wounding triggers an inflammatory response that can exac

285 Here we report that tissue and cellular wounding triggers rapid and reversible mitochondrial fra

286 Wounding triggers the formation of arrays of Rho GTPases

287 Upon wounding using a 2 mm biopsy punch, the impedance droppe

288 lites produced as a response to potato tuber wounding, using activity-guided fractionation of polar e

289 Wounding was applied by shredding carrots and storing th

290 Cell migration following wounding was decreased when PP5 expression was decreased

291 In response to cornea debridement wounding, we find increased expression of MAGP1 througho

292 lics that showed the highest increase due to wounding were the chlorogenic (579.8%) and p-coumaric (3

293 ellular origin, lineage infidelity occurs in wounding when stress-responsive enhancers become activat

294 e capable of fusing with lysosomes following wounding which may contribute to formation of large woun

295 kin is down-regulated in favor of FSTL1 upon wounding, which enhances keratinocyte migration and prom

296 e coating remains intact even after multiple wounding, while cell debris is simultaneously removed us

297 wounding in zebrafish, we show that repeated wounding with subsequent inflammation leads to a greater

298 y, mice were euthanized and pelted to assess wounding with the pelt aggression lesion scale (PALS).

299 ions were used as a model of corneal stromal wounding, with markers of corneal fibrosis and opacity s

300 ly reproduce and to repair tissues following wounding; yet plant cells normally stably maintain consi