ライフサイエンスコーパス: yeast

1 onal relationship between Coq10 and Coq11 in yeast.

2 athway for relocating activated gene loci in yeast.

3 H3 variant Cse4(CENP-A) at the centromere in yeast.

4 or fMAPK) but not p38-type pathways (HOG) in yeast.

5 loid pathway to produce (S)-norcoclaurine in yeast.

6 GET1 rescues growth defects of Deltaget1get2 yeast.

7 matched GI datasets from baker's and fission yeast.

8 l survival and mating-type switch in haploid yeast.

9 g coding sequences impact fitness in budding yeast.

10 ct synthesis and large-scale fermentation in yeast.

11 ic inheritance of heterochromatin in fission yeast.

12 mics (MD) simulations and in vivo mutants in yeast.

13 d the effects of VPA on energy metabolism in yeast.

14 ity of TIS into nonbacterial species such as yeast.

15 gest that bet hedging has evolved in budding yeast.

16 Sup35 amyloid, promoting its persistence in yeast.

17 on in Ljsen1 plants reduce iron transport in yeast.

18 drial and nuclear DNA of budding and fission yeast.

19 in all Eukaryotes-mostly animals, plants and yeasts.

20 parasites that have co-evolved with budding yeasts.

21 some assembly system is more complex than in yeasts.

22 was fermented with different commercial beer yeast (Abbaye, Diamond, SafAle, SafLager) in order to mo

23 hile much has been learned from bacteria and yeast about translational regulation, much less is known

24 lecules may confer protection to neighboring yeasts against azoles, in turn strengthening their co-ex

25 Yeast, allowing genetic manipulation that is not easily

26 Yeast AMP-activated protein kinase (AMPK) directly phosp

27 t C. albicans cells, and it bound to Adh1 in yeast and Adh2 in hyphae among the cell wall-associated

28 es to pressure of live cells from mesophilic yeast and bacterial strains, as well as the piezophilic

29 tudied as a general RNA-processing factor in yeast and cultured cells.

30 We have tested Pomegranate on fission yeast and demonstrate its ability to 3D segment wild-typ

31 ed disome and trisome footprint profiling in yeast and found collisions were enriched on diverse sequ

32 pplication of STRIPE-seq to TSS profiling in yeast and human cells and show that it can also be effec

33 red for Z-DNA-induced genetic instability in yeast and human cells.

34 Here, yeast and human EMC cryo-EM structures reveal conserved

35 Moreover, this clustering is similar in yeast and human kinetochores despite significant differe

36 o-EM) structures of translationally inactive yeast and human ribosomes.

37 Systematic data sets of both types exist for yeast and human, but they rarely converge on a common se

38 s the high-confidence TF network map in both yeast and human.

39 in single-celled organisms like bacteria and yeast and immobile organisms like plants that constantly

40 y balance significant mechanical stresses in yeast and in cells from higher organisms.

41 f the eIF2alpha kinase CPC-3 (the homolog of yeast and mammalian GCN2), and rhythmic activation of CP

42 aryotes and have been intensively studied in yeast and mammals.

43 f the settled must was 4-log CFU/mL for both yeast and moulds, and slightly lower for bacteria.

44 Yeast and mouse mimics of the most common variant, P286R

45 Yeast and other organisms live longer when they lack spe

46 hoices for potential applications in fission yeast and other organisms.

47 This suggests that in animals, as in yeast and plants, myosin/actin can drive long-range tran

48 strain created for broad applications in the yeast and synthetic biology communities that contains on

49 agonized TDP-43 condensation and toxicity in yeast and TDP-43 aggregation in human cells.

50 m to characterize GAA repeat contractions in yeast and to conduct a genetic analysis of this process.

51 Native yeast and yeast cell wall particles (YCWPs) were used as

52 ed normal respiratory flora alone (including yeast), and 0.6% contained mycobacteria/molds.

53 nase activity, and transcription in mammals, yeast, and bacteria.

54 GWG decreased the growth of total bacterial, yeast, and mold in germinated seeds.

55 t expression of NPA-sensitive PINs in plant, yeast, and oocyte membranes leads to specific saturable

56 ing cellular Ca(2+) homeostasis in bacteria, yeast, and plants by promoting Ca(2+) efflux across the

57 A (ssDNA), have been identified in bacteria, yeasts, and other eukaryotic organisms.

58 Using yeast- and human-extract screenings, we identified five

59 bolites have been shown to activate TORC1 in yeast, animals, and plants.

60 Yeast antiprion systems composed of PQC factors act at n

61 Our initial analysis of yeast Arb1/Abcf2 in disaggregation and animal ABCF prote

62 inding characteristics we observe in fission yeast are likely to apply to related proteins in higher

63 During winemaking, yeasts are removed after fermentation by racking, filtra

64 overies of the mechanisms of autophagy using yeast as a model organism.

65 Here, we discover that Z-DNA is mutagenic in yeast as well as human cells, and that the nucleotide ex

66 ific dwell times that differed from those in yeast, as well as pairs of adjacent codons in the P and

67 min A variants was assessed using an in vivo yeast assay that provides a sensitive measure of ZMPSTE2

68 containing ULK1 or ULK2 (two paralogs of the yeast Atg1 protein).

69 We developed a generalizable yeast-based platform for directed evolution of protease

70 this approach to build a set of 10 versatile yeast-based reporter strains for studying human G protei

71 stem was originally described in mammals and yeast but was recently shown to be partially conserved i

72 charomyces cerevisiae and some other budding yeasts, but most eukaryotes lack sequence-specific origi

73 mutations improve function of hHsp90alpha in yeast by accelerating return to the open state.

74 or Set2, the sole H3K36 methyltransferase in yeast, by fusing the enzyme with the light-activated nuc

75 y the expression of the cytosolic isoform of yeast CAE, even though it was not imported into mitochon

76 en a bacterium, Pseudomonas aeruginosa and a yeast, Candida albicans, induce the resistance of the la

77 by both plasmolysed (PYC) and nonplasmolysed yeast cell (NPYC) and stability of thymoquinone and bioa

78 o the time course of fluorescence signal per yeast cell expressing mEos3.2.

79 sently, commercial MOS is being derived from yeast cell wall mannan and is widely used as prebiotic i

80 Native yeast and yeast cell wall particles (YCWPs) were used as model cel

81 correlations across hundreds of thousands of yeast cells and reveals ample evidence of both vertical

82 Screening with yeast cells and various strains of both Gram-positive an

83 itinated ribosomes from oxidatively stressed yeast cells at 3.5-3.2 angstrom resolution.

84 ublocations within mitochondria of respiring yeast cells by fusing a pH-sensitive GFP to proteins res

85 RNA quantities is apparent in single fission yeast cells during a normal cell cycle.

86 The HPF1 repeat expansion shifted yeast cells from a sedentary to a buoyant state, thereby

87 we identified 377 IVC-associated proteins in yeast cells grown under steady-state low-glucose conditi

88 Compromising the activity of Ddi1 in yeast cells results in the accumulation of polyubiquitin

89 novative single-molecule imaging approach in yeast cells to measure chromatin association of individu

90 Yeast cells with arginine-to-alanine mutations in the H4

91 t MAb 4D1 binds to and recognizes conidia to yeast cells' transition inside of a human monocyte-like

92 icochemical parameters of replicatively aged yeast cells.

93 escently labeled circular chromosome in live yeast cells.

94 our well-understood models of mammalian and yeast cells.

95 t the hydrophobic patch targets Cdc13 to the yeast centrosome equivalent, the spindle pole body (SPB)

96 To date, a similar analysis of yeast colonies has not proved possible.

97 emperatures, using both free and immobilized yeast) combined with baker's yeast production (with mino

98 missense variants, through a combination of yeast complementation and enzymatic assays, show impaire

99 Recent cryo-EM analyses of mammalian and yeast complex I have revolutionized structural and mecha

100 o single-molecule experiments confirmed that yeast condensins extrude loops, however, they remain anc

101 as associated with time of exposure, mold to yeast conversion, and mammalian temperature.

102 ia from TAZ-KO mouse cells and in CL-deleted yeast crd1Delta cells, indicating that the role of CL in

103 al importance of the Arabidopsis ortholog of yeast CWC15.

104 49) fragment within the primary structure of yeast cyclophilin CPR1 by replacing its homologous seque

105 he evaluation experiments conducted on three yeast datasets have shown that IMPRes can achieve compet

106 e screened the genome-wide library of viable yeast deletion mutants for defects in the degradation of

107 alization of Ipl1 to kinetochores in budding yeast depends upon multiple pathways, including the Bub1

108 led to reduced sleep in normally fed but not yeast-deprived males.

109 sses the scarcity of platforms available for yeast despite their prevalent use in industry and academ

110 ccus aureus We identified this antibody in a yeast display screen built from mononuclear cells isolat

111 In summary, our yeast-display-based platform yields high-quality MHC-II-

112 A large region of fission yeast DNA inserted into a mouse chromosome was previousl

113 In most yeast-driven biotechnological applications, biomass is s

114 ality, once it is related to the vitality of yeast during the initial exponential growth phase and th

115 Whereas bacteria and yeast each have only two sHsps in their genomes, this nu

116 la mucilaginosa JGTA-S1 is a basidiomycetous yeast endophyte of narrowleaf cattail (Typha angustifoli

117 This finding indicated that the yeast enzyme complements the essential function of TbCAE

118 e evolutionary sequence in a 1000-generation yeast evolution experiment.

119 discoideum and macrophages with recombinant yeast exopolyphosphatase reduced the survival of phagocy

120 Indeed, the yeast exposed to the host takes on pleiotropic phenotype

121 enous populations, indicating that in social yeasts Flo11A-mediated cell adhesion is a major mechanis

122 of serine protease from Yarrowia lipolytica yeast for reduction of milk proteins allergenicity.

123 expression data sets of Multiple tissues and Yeast from two different organisms (Homo Sapiens and Sac

124 standing of how ratio-sensing is achieved in yeast GAL metabolic regulation, but also elucidated desi

125 was discovered approximately 20 years ago by yeast genetic screens identifying it as a factor respons

126 integrative structural biology combined with yeast genetics and biochemistry to highlight the specifi

127 We combined yeast genetics and Gag mutational analysis with Gag-ESCR

128 ical contexts (e.g., cancer, mouse genetics, yeast genetics).

129 proach on a simulated trio of pseudo-diploid yeast genomes with different heterozygosity rates, and r

130 c reticulum (ER) membrane with an insertase (yeast Get1/Get2 or mammalian WRB/CAML) that captures the

131 omology but high structural homology to both yeast Get2 and mammalian CAML.

132 are more sensitive to debranching by fission yeast GMF (glia maturation factor) than branches with AD

133 While the 'humanized' yeast grew in the absence of adenine, it did so poorly.

134 To this end, we employed a ROMK-dependent yeast growth assay and tested single amino acid variants

135 nol (H23), as a first-in-class inhibitor for yeast GS 2 (yGsy2p).

136 h conservation of residues between human and yeast GS in direct contact with H23 informed the develop

137 Being Crabtree-positive, this yeast has evolved the ability to ferment glucose to etha

138 ell cycle mutants in the budding and fission yeasts have played critical roles in working out how the

139 We determine the structure of the yeast histone H3-H4 complex based on ~500,000 genetic in

140 While most kinases upstream of the yeast histone methylation enzymes remain unknown, we mod

141 -independent induction system to express the yeast HO endonuclease or bacterial restriction enzymes f

142 ckayne syndrome group B (CSB) protein or its yeast homolog Rad26.

143 ere, we find that involvement of the budding yeast Hsp70 chaperones Ssa1 and Ssa2 in nuclear PQC degr

144 These new synthetic yeast hybrids and the iHyPr method have potential applic

145 e phenotype gene-deletion strains of fission yeast in 59,350 individual fitness assays in 70 conditio

146 have been described in wines and the role of yeast in their formation is clear.

147 GARP mutations in yeast, including one causing PCCA2, result in sphingolip

148 Selective pressures and competition between yeasts influenced microbial growth and metabolite produc

149 ay robustly detects small changes in budding yeast initiation kinetics, which could not be resolved b

150 and alcohols content, thus proving that the yeast-inoculating form may typify the odor and flavor de

151 ere not remarkably affected by the different yeast-inoculating form.

152 Effect of yeast inoculation format (F), temperature (T), and "on l

153 H3K4 methylation in yeast is catalyzed by Set1, the methyltransferase subuni

154 Saccharomyces cerevisiae flor yeast is used for the first time in sparkling wine-makin

155 cked the microtubule end-binding activity of yeast kinesin-8, Kip3, under varying loads and nucleotid

156 binogenic filament and the donor template in yeast, limiting strand rejection by the Sgs1 and Mph1 he

157 led sample of bovine serum albumin (BSA) and yeast lysates mixed at different ratios.

158 t as a factor responsible for processing the yeast mating a-factor pheromone.

159 potential for autophagy to regulate budding yeast meiosis.

160 Directed evolution of PLD using yeast membrane display and IMPACT, a chemoenzymatic meth

161 ination of translation efficiency across the yeast membrane proteome revealed that polytopic membrane

162 AD(+) levels and restores NAD(+) uptake into yeast mitochondria lacking endogenous NAD(+) transporter

163 e developed a computational model of fission-yeast mitosis.

164 egion, the hydrophobic patch, on the fission yeast mitotic cyclin Cdc13 as a potential mechanism to c

165 complement the thermosensitive growth of the yeast mms19 deletion mutant while expression of the dimi

166 study of endogenous K-PPn of proteins in the yeast model system is that its nonenzymatic nature and i

167 Retention of peroxisomes in yeast mother cells requires Inp1, which is recruited to

168 In human and yeast mRNAs, ac(4)C sites are not detected but can be in

169 rved stretch within the regulatory region of yeast MTHFR to create a series of feedback-insensitive,

170 nscription initiation intermediate states of yeast mtRNAP that explain promoter melting, template ali

171 , and C45G3.3 completely rescue bacterial or yeast mutants affected in different steps of the lipoyla

172 ying how the fitness of hundreds of adaptive yeast mutants responds to subtle environmental shifts.

173 To systematically validate yeast mutants that disrupt ER membrane homeostasis, we i

174 d from a variety of model systems, including yeast, nematode, fruit fly, and zebrafish, and discuss e

175 CN dephosphorylates human and yeast NPC proteins and promotes accumulation of a nuclea

176 In yeast, nucleosomes inhibit nucleotide excision repair (N

177 Here, we used enhanced yeast one-hybrid (eY1H) assays to derive a comprehensive

178 We therefore used a large-scale enhanced yeast one-hybrid assay to identify potential regulators

179 Similar to yeast Pam18, TbPam27 requires an intact J-domain to func

180 ic complex genetic interaction analysis with yeast paralogs derived from the whole-genome duplication

181 entify other factors that act in the budding-yeast pathway, we performed an unbiased genetic selectio

182 nspired by this concept, herein we transform yeast peroxisomes into microfactories for geranyl diphos

183 The fission yeast phosphate homeostasis (PHO) regulon comprises thre

184 and more generally, showcases the utility of yeast phospholipid mutants in dissecting the phospholipi

185 Yeast physiology is temporally regulated, this becomes a

186 We explored this issue using the yeast Pichia pastoris.

187 The yeast plasma membrane is unusual in that it may have a h

188 Therefore, we tested how the yeast plasma membrane P4-ATPase, Dnf2, responds to chang

189 The yeast PM is segregated into the Micro-Compartment-of-Can

190 Yeast Pole-P301R has increased DNA polymerase activity,

191 The yeast prion [URE3] propagates as a misfolded amyloid for

192 An N-terminal hepta-peptide sequence of yeast prion protein Sup35 with the sequence GNNQQNY is w

193 Yeast prions provide self-templating protein-based mecha

194 These results support the advantages of yeast produced triterpene oils to include completely con

195 and immobilized yeast) combined with baker's yeast production (with minor nutrient supplementation),

196 ver, we propose that global transcription at yeast promoters is responsible for eviction of H2A.Z.

197 We next cross-link the yeast proteasome, identifying 3,893 unique cross-linked

198 of vacuolar polyP metabolism to K-PPn of two yeast proteins, Top1 (DNA topoisomerase 1) and Nsr1 (nuc

199 capability by characterizing changes in the yeast proteome in response to environmental perturbation

200 ag was demonstrated by triplex labeling of a yeast proteome spiked with bovine serum albumin (BSA) ov

201 Fission yeast Rai1 also has HDH activity although it does not ha

202 ammalian DXO with 3'-FADP or CoA and fission yeast Rai1 with 3'-FADP provide elegant insight to these

203 SARs) mark the cargo for degradation and, in yeast, recruit Atg11, the scaffolding protein for select

204 In yeast, recruitment of Vps13 to different contact sites o

205 4-dependent signaling in a receptor-specific yeast reporter system and in CXCR4-expressing human HEK2

206 nterface made exclusively by Cox5A, the only yeast respiratory protein that exists as one of two isof

207 motes degradation of all rRNA species of the yeast ribosome and that it is bound directly to RNA mole

208 Equivalent mutations in yeast Rqc2 selectively interfere with its ability to mod

209 aced into the orthologous Sth1 ATPase of the yeast RSC remodeler, separate into two categories: loss-

210 ites (TSSs) has been identified in a budding yeast Saccharomyces cerevisiae ("scanning model").

211 an 800 000 atom model of SPL C complex from yeast Saccharomyces cerevisiae and community network ana

212 The budding yeast Saccharomyces cerevisiae divides asymmetrically, l

213 ng experimental growth curves of the baker's yeast Saccharomyces cerevisiae growing in the presence o

214 The yeast Saccharomyces cerevisiae is a powerful model syste

215 The Nem1-Spo7 complex in the yeast Saccharomyces cerevisiae is a protein phosphatase

216 ondrial respiration and Sod1 function in the yeast Saccharomyces cerevisiae The histone H3-H4 tetrame

217 Recently Opi3, a PLMT of the yeast Saccharomyces cerevisiae was proposed to perform i

218 In the yeast Saccharomyces cerevisiae, the Nt-amidase, arginylt

219 scent reporters in single, live cells of the yeast Saccharomyces cerevisiae.

220 sed for most genetic construct design in the yeast Saccharomyces cerevisiae.

221 single-strand annealing (SSA) assays in the yeast Saccharomyces cerevisiae.

222 5 by heterologously expressing it in budding yeast (Saccharomyces cerevisiae) and in the bacterium La

223 subunit Rrp44/Dis3 of the exosome in budding yeast (Saccharomyces cerevisiae) is considered a protein

224 Budding yeast (Saccharomyces cerevisiae) responds to low cytosol

225 lear Auxin Response Circuit recapitulated in yeast (Saccharomyces cerevisiae) system to functionally

226 In budding yeast (Saccharomyces cerevisiae), EVs function as carrie

227 K-PPn was originally discovered in budding yeast (Saccharomyces cerevisiae), in which polyP anaboli

228 s), fruit fly (Drosophila melanogaster), and yeast (Saccharomyces cerevisiae), this core NatA complex

229 e developed a method for scRNAseq in budding yeast (Saccharomyces cerevisiae).

230 The mitochondrial protein Atg32 is the yeast SAR that mediates mitophagy, the selective autopha

231 hese fundamental questions using the fission yeast Schizosaccharomyces japonicus, which breaks and re

232 In the fission yeast Schizosaccharomyces pombe, H3K9me heterochromatin

233 this concept in two pathogenic Cryptococcus yeast species by genome-wide mapping of translation and

234 human DNMT genes in Komagataella phaffii, a yeast species lacking endogenous DNA methylation.

235 ctions between Flo11A domains from different yeast species or Saccharomyces cerevisiae strains confer

236 developed in this study employing a special yeast species Saccharomycodes ludwigii.

237 cerevisiae, RNAi is present in other budding-yeast species, including Naumovozyma castellii, which ha

238 Based on these results, the mixture of both yeasts species is a promising starter for cocoa fermenta

239 Additionally, we present a BY4741 yeast strain created for broad applications in the yeast

240 Taking advantage of a yeast strain deficient for heme production that enabled

241 osolic and nuclear targets, we constructed a yeast strain devoid of vacuolar polyP by targeting the e

242 We therefore engineered a yeast strain expressing a new type of Split-GFP that we

243 Here, we use SCRaMbLE to optimise yeast strains engineered to produce the triterpenoid bet

244 Yeast strains harboring the chimeric Mre11/Rad50 complex

245 Different yeast strains showed various extents of antioxidant acti

246 In summary, our analysis of mutations in yeast strains treated with alkylating agents, as well as

247 of ice apple juices and three autochthonous yeast strains were evaluated.

248 the frequency of the two states across wild yeast strains.

249 ons were performed in wooden boxes and eight yeasts strains were used in separated fermentations of f

250 ia expression of a PI(4)P-binding protein in yeast strongly inhibited TBSV replication.

251 Here, we report the use of yeast surface display to engineer an anti-VISTA antibody

252 ain variable fragment (scFv), identified via yeast surface display, that specifically binds to the NP

253 d affinity for its IL-10Rbeta receptor using yeast surface display.

254 By screening a yeast surface-displayed library of synthetic nanobody se

255 me-wide in an ATP-dependent manner, like the yeast SWR1 complex.

256 Using a yeast system (Saccharomyces cerevisiae), we experimental

257 ature sensitive POP1 and POP6 alleles affect yeast telomerase.

258 merase to be active in vitro and to maintain yeast telomeres in vivo, whereas the DeltaCEH and 1- and

259 is et al. report two crystal structures of a yeast tethering factor, the Dsl1 complex, bound with two

260 In fission yeast, the inverted repeats IR-L and IR-R function as bo

261 In yeast, the major cytosolic peroxiredoxin, Tsa1 is requir

262 Prior to anaphase of budding yeast, the ribosomal DNA (RDN) condenses to a thin loop

263 In fission yeast, the septation initiation network (SIN) ensures te

264 In budding yeast, the transcription factors SBF and MBF activate a

265 We report that the [SMAUG(+)] prion allows yeast to anticipate nutrient repletion after periods of

266 roach quickly merged with genetic studies in yeast to establish the basic mechanism of the eukaryotic

267 of alpha and beta heterodimer conserved from yeast to human.

268 ly members are evolutionarily conserved from yeast to humans, and they are known to be key factors in

269 tric cell division in organisms ranging from yeast to humans.

270 urthermore, this is the first description in yeast to our knowledge of a cis-translated protein inter

271 other actin-related filaments and may allow yeast to rapidly modulate glucokinase activity as nutrie

272 Yeast tolerates a low pH and high solvent concentrations

273 We describe the isolation of a yeast top2 mutant (top2-F1025Y,R1128G) the product of wh

274 First, we use an in vitro reconstituted yeast translation system to demonstrate that inhibitory

275 Here, we show that LDs induced by the yeast triacylglycerol (TAG)-synthases Lro1 and Dga1 are

276 TRAPPC4, like its yeast Trs23 orthologue, is a core component of the TRAPP

277 These results were validated using a yeast trs23 temperature sensitive variant that exhibits

278 Affinity purification and pairwise yeast two-hybrid analysis suggest that ZC3H5 forms a com

279 otein: protein interaction studies including yeast two-hybrid and Bimolecular Fluorescence Complement

280 pair (GRMZM2G035341 and GRMZM2G152328) using yeast two-hybrid and bimolecular fluorescent complementa

281 Utilizing a yeast two-hybrid assay, we discovered several novel inte

282 iching for the interacting fragments using a yeast two-hybrid reporter system.

283 ins involved in PPIs by advancing the use of yeast two-hybrid technology.

284 RISPR-assisted RNA-RNA-binding protein [RBP] yeast) two-hybrid assay to assess binding of our CEH mut

285 In aneuploid budding yeast, two opposing gene-expression patterns have been r

286 Here, we have used yeast-two-hybrid screening to identify OsPIP5K1, a membe

287 We show that budding yeast Ty3/Gypsy co-opts binding sites of the essential m

288 on membrane fusion, and recent studies with yeast vacuolar SNAREs uncovered asymmetry in the results

289 However, yeast vacuoles accumulate large amounts of polyP, and up

290 constituted fusion with pure components from yeast vacuoles including SNAREs, the HOPS (homotypic fus

291 Moreover, yeast vacuoles possess two very active endopolyphosphata

292 Using replication fork barriers in fission yeast, we report that relocation of arrested forks to NP

293 ver, the spectra and signatures derived from yeast were detectable in lung cancers, head and neck can

294 to unexpected social exploitation: snowflake yeast, which do not produce adhesive FLO1, nonetheless b

295 0 (human lung fibroblast), and (iii) budding yeast whole-genome Hi-C data at a single restriction cut

296 eaweed hydrolysates and seawater with marine yeast Wickerhamomyces anomalus M15 produced 48.24 +/- 0.

297 faster than floc alone, providing snowflake yeast with a fitness advantage during competition.

298 sing deep mutational scanning, we engineered yeast with all 44,604 single codon changes encoding 14,1

299 lbox of cell cycle tag constructs in budding yeast with defined and compatible peak expression that a

300 y sourdough fermentation of wheat flour with yeast (YAK) or buttermilk (BAK).