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1 strains, such as KIM5, lack the siderophore yersiniabactin.
2 ch encodes a transporter for the siderophore yersiniabactin.
3 olved in the biosynthesis of the siderophore yersiniabactin.
4 d to genes for enterobactin, aerobactin, and yersiniabactin.
5 of the newly detected VF genes, e.g., fyuA (yersiniabactin; 76%) and focG (F1C fimbriae; 25%), were
6 ichromes, aerobactin), mixed iron complexes (yersiniabactin, acinetobactin, pyoverdine), and porphyri
7 oducing polyketide synthase (PKS) modules of yersiniabactin and epothilone were characterized using m
8 lmochelin) and non-catecholate siderophores (yersiniabactin and ferrichrome) fail to inhibit MPO acti
9 erophores for high-affinity iron scavenging, yersiniabactin and pyoverdin, and we uncover a third sid
11 hiazoline-containing siderophores pyochelin, yersiniabactin, and Micacocidin A all have D-thiazoline
12 we show that Nissle utilizes the siderophore yersiniabactin as a zincophore, enabling Nissle to grow
13 shown to synthesize a siderophore molecule, yersiniabactin, as a virulence factor during iron starva
14 ae vibriobactin and HMWP2 of Yersinia pestis yersiniabactin assembly lines were evolved by random mut
16 gen-associated iron acquisition systems like yersiniabactin, common among pathogenic species in the f
18 and salmochelin deficient), hvKP1Deltairp2 (yersiniabactin deficient), and hvKP1DeltaentBDeltairp2 (
21 re receptors for salmochelin, aerobactin, or yersiniabactin displayed reduced fitness in wild-type mi
22 tant (strain 536DeltafyuA) unable to acquire yersiniabactin during infection, we established the yers
23 e activity being enterobactin > aerobactin > yersiniabactin > salmochelin, suggesting that the contri
24 tte (ABC) proteins associated with iron(III)-yersiniabactin import in Yersinia pestis In this study,
26 ity to produce enterobactin, salmochelin, or yersiniabactin individually or in combination did not de
27 nd sfaS (S fimbriae), hly (hemolysin), fyuA (yersiniabactin), iroN (siderophore), and ompT (outer mem
28 monstrated that production of colibactin and yersiniabactin is abolished in the absence of Hsp90Ec We
30 mbly of the iron-chelating virulence factor, yersiniabactin of the plague bacterium Yersinia pestis.
32 o form a gem-dimethylated product, while the yersiniabactin PKS could methylate before or after ketos
33 in positive (Ent(+)) (81%), enterobactin and yersiniabactin positive (Ent(+) Ybt(+)) (17%), and enter
34 ld be cross-fed by culture supernatants from yersiniabactin-producing strains of Y. pestis grown unde
36 genes encoding for multi-drug resistance and yersiniabactin production compared with colonizing isola
37 that synthesize vibriobactin, enterobactin, yersiniabactin, pyochelin, and anguibactin, we examined
38 the nikkomycin, clorobiocin, coumermycin A1, yersiniabactin, pyochelin, and enterobactin biosynthetic
39 abactin during infection, we established the yersiniabactin receptor as a UPEC virulence factor durin
41 aerobactin receptor mutant and the DeltafyuA yersiniabactin receptor mutant, were frequently outcompe
42 bmaE (M fimbriae), gafD (G fimbriae), fyuA (yersiniabactin receptor), ireA and iroN (novel sideropho
43 urine and blood) isolates separately: fyuA (yersiniabactin receptor), kpsM K1 (K1 capsule), and kpsM
44 produce yersiniabactin, suggesting that this yersiniabactin-related locus is functionally distinct.
46 dings clearly show that proteobactin and the yersiniabactin-related siderophore function as iron acqu
47 both siderophores, only mutants lacking the yersiniabactin-related siderophore have reduced fitness
50 P. mirabilis is unable to utilize or produce yersiniabactin, suggesting that this yersiniabactin-rela
51 ing sites, designated sid, is similar to the yersiniabactin synthesis and uptake genes encoded on the
53 l structure of the second Cy domain (Cy2) of yersiniabactin synthetase from the causative agent of th
54 (1896-3163) of the 350-kDa HMWP1 subunit of yersiniabactin synthetase have been expressed in and pur
56 from surfactin synthetase and Ybt PCP1 from yersiniabactin synthetase, was observed at rates of 0.5
59 that iron acquisition systems, including the yersiniabactin system, are highly expressed by bacteria
60 [uropathogenic-specific protein], and fyuA [yersiniabactin system]) were most closely associated wit
66 biosynthesis, pyrazinone signaling enhances yersiniabactin virulence factor production and selective
67 produced by uropathogenic Escherichia coli, yersiniabactin, was found to also bind copper ions durin
68 for the synthesis of either enterobactin or yersiniabactin were constructed, and the growth of these
69 thogenicity island, encoding the siderophore yersiniabactin, which belongs to the same chemical famil
70 nthetase that biosynthesizes the siderophore yersiniabactin (Ybt) activates three molecules of L-cyst
71 tructurally distinct siderophores, including yersiniabactin (Ybt) and glycosylated Ent (GlyEnt, or sa
72 strains capable of producing the siderophore yersiniabactin (Ybt) and the putative ferrous transporte
74 n Yersinia pestis, the siderophore-dependent yersiniabactin (Ybt) iron transport system and heme tran
75 g the synthetase (HMWP2) for the siderophore yersiniabactin (Ybt) is required for growth under Zn(2+)
77 strated that AIEC producing the metallophore yersiniabactin (Ybt) promotes intestinal fibrosis in an
78 he causative agent of bubonic plague, is the yersiniabactin (Ybt) siderophore-dependent iron transpor
79 s, causative agent of bubonic plague, is the yersiniabactin (Ybt) siderophore-dependent iron transpor
80 a pestis has multiple iron transporters, the yersiniabactin (Ybt) siderophore-dependent system plays
83 229 kDa HMWP2 subunit of the Yersinia pestis yersiniabactin (Ybt) synthetase has been expressed in so
85 studies with pyochelin (Pch) synthetase and yersiniabactin (Ybt) synthetase reconstituted from pure
88 oduces an iron-scavenging siderophore called yersiniabactin (Ybt) that is required to overcome iron-m
89 and (HPI), which directs the biosynthesis of yersiniabactin (Ybt), a virulence-associated metallophor
90 hesis of SA, the SA-incorporated siderophore yersiniabactin (Ybt), and the fluorescent siderophore py
91 thesis of the Y. pestis cognate siderophore, yersiniabactin (Ybt), and which is located immediately u
92 agent of plague, makes a siderophore termed yersiniabactin (Ybt), which it uses to obtain iron durin