ライフサイエンスコーパス: young

1 r differences in response between adults and young.

2 nds, causes, and risk factors for SCD in the young.

3 sk factors for specific causes of SCD in the young.

4 assessed using Doppler flow and telemetry in young (14-16 weeks) and old (57-60 weeks) wild-type and

5 nerative response to injury in comparison to young (2-3 months old) mice.

6 sequencing to identify bacterial profiles in young (3 to 7 y) and adult (12 to 23 y) animals.

7 Most were young (38 yrs) males (84%) with blunt injuries (51%).

8 Here, we investigate whether young ABN activity contributes to memory consolidation d

9 xtual fear learning recruits a population of young ABNs that are reactivated during subsequent REM sl

10 Adolescent and young adult (AYA) patients need additional support, whil

11 omes among survivors of early-adolescent and young adult cancer (aged 15-20 years at diagnosis) and s

12 .2 [95% CI 3.7-4.8] for early adolescent and young adult cancer survivors and 5.6 [4.9-6.3] for child

13 Early-adolescent and young adult cancer survivors and childhood cancer surviv

14 g of both childhood and early-adolescent and young adult cancer survivors.

15 male survivors of childhood, adolescent, and young adult cancer.

16 lity among survivors of early-adolescent and young adult cancer.

17 onses in aged MAIT cells compared with their young adult counterparts when fold change in expression

18 This was 'biographically' during young adult development and across 'cancer time'; throug

19 malignancy occurring primarily in adolescent/young adult males, we used next-generation RNA sequencin

20 To test this hypothesis, we infected young adult mice with either of two genetically distinct

21 affect baseline cardiac size or function in young adult mice.

22 apparent post-transcriptional repression in young adult mouse HSCs.

23 erived from screening studies, most often of young adult populations, to assess cardiovascular risk o

24 identify this timepoint in a novel cohort of young adult premanifest Huntington's disease gene carrie

25 se risks were lower for early-adolescent and young adult survivors than for childhood cancer survivor

26 ed nucleic acid antisense oligonucleotide to young-adult aspartoacylase-deficient mice reverses their

27 n immune-cell gene regulation that emerge by young adulthood and may help explain social disparities

28 natures of myocardial and vascular health in young adulthood specify known/novel pathways of metaboli

29 g any behavior of despair in adolescence and young adulthood.

30 valuation of FASD in childhood as well as in young adulthood.

31 age 9 to 10 for approximately ten years into young adulthood.

32 n concentration through late adolescence and young-adulthood.

33 hest prevalence of constipation in women and young adults (19.7 and 23.5%, respectively).

34 ensity, urban regions preferentially attract young adults (25-40 years) and lose older people (> 45 y

35 years) generated 50% fewer FAPs compared to young adults (25.0 years) and teenagers (13.8 years).

36 domly assigned, in a 2:1 ratio, children and young adults (age range, 6 to 21 years) with newly diagn

37 mmes whose coverage encompassed children and young adults (aged 20 and below) were highly cost-effect

38 In addition, TRIAD included healthy young adults (mean age 23 years) and BioFINDER-2 include

39 of attention(20,21) were recorded as eighty young adults (mean age, 21.7 years) performed a goal-dir

40 Methods: We assessed 176 individuals [young adults (n = 22), cognitively unimpaired elderly (n

41 The participants were young adults (n=525; mean age 21.5 +/- 3.0 years; mean B

42 nd IQ-matched male typically developing (TD) young adults 18-25 years old.

43 Young adults aged 18 to 25 years have a higher rate of c

44 5% CI 48-73); 69% (54-87) in adolescents and young adults aged 18-39 years.

45 west concentrations in amyloid beta-negative young adults and cognitively unimpaired older adults, th

46 cohort of children with overweight/obesity, young adults and middle-age adults.

47 hy to measure mGlu5 receptor availability in young adults at elevated risk for addictions.

48 l cancer (CRC) incidence is increasing among young adults below screening age, despite the effectiven

49 that impact sleep and circadian function for young adults of differing races and sexes.

50 tumor (DSRCT), a rare sarcoma of adolescents/young adults primarily involving the peritoneum, has a l

51 National-level HIV prevalence for young adults ranged from 2.2% in Tanzania to 7.7% in Moz

52 Healthy young adults received two doses of either formulation 3

53 CARDIA (Coronary Artery Risk Development in Young Adults Study).

54 Coronary Artery Disease Risk Development in Young Adults study, a cohort of black and white young ad

55 Approximately a third of young adults surveyed were experiencing at least one GI

56 Here, we showed in 15 healthy young adults that VZV-specific B and CD4 T cell response

57 n of health and social services in high-risk young adults to improve TB control efforts.

58 iological and graded cognitive challenges in young adults to investigate the actions of dietary flava

59 ss the QoL and LS and their predictors among young adults treated for PCG during early childhood.

60 No trials of prevention in young adults were identified.

61 uses asthma exacerbations among children and young adults who are allergic.

62 he United State, with outbreaks occurring in young adults who have been vaccinated.

63 gnificant reduction in neural suppression in young adults with autism spectrum disorder (ASD) compare

64 e routine care of children, adolescents, and young adults with cancer has resulted in improved outcom

65 dentify common breathing patterns in healthy young adults with distinct influences on functional conn

66 estigations of brain anatomy in children and young adults with Down syndrome (DS) are limited, with n

67 Moreover, young adults with Down syndrome also displayed increased

68 p between sTREM2 and inflammatory markers in young adults with DS, prior to the development of dement

69 he ocular adnexa can develop in children and young adults with long-term PGA exposure.

70 We recruited young adults with preHD and controls matched for age, ed

71 tand the challenges faced by adolescents and young adults with these conditions.

72 his study compared long-term mortality among young adults with type 1 MI, type 2 MI, or myocardial in

73 Young adults with type 2 diabetes (aged 18-39 years) are

74 cribe the impact of a diagnosis of cancer on young adults' sense of biography and identity.

75 A study (Coronary Artery Risk Development in Young Adults), a community-based cohort of young individ

76 tored vaccine, ChAdOx1 nCoV-19 (AZD1222), in young adults, and now describe the safety and immunogeni

77 440 h of resting state scans in 440 healthy young adults, both caused by deviations from normal brea

78 3 null mice exhibit a spermatogenic block as young adults, the mechanism of which remains poorly unde

79 ng Adults study, a cohort of black and white young adults, we evaluated the associations of E-selecti

80 lating them to cardiac muscle performance in young adults.

81 ve syndrome among children, adolescents, and young adults.

82 68% (58-81); 74% (60-91) in adolescents and young adults.

83 reatment response assessment in children and young adults.

84 poplasia was recorded in 3 children and in 4 young adults.

85 unknown for other anthropometric indexes in young adults.

86 risk factors among offspring when they were young adults.

87 ial infarction-cardiogenic shock (AMI-CS) in young adults.

88 romotes glucose oxidation and lipogenesis in young adults.

89 ofile for drug use or abuse, particularly in young adults.

90 ost common disabling neurological disease in young adults.

91 and wellbeing of children, adolescents, and young adults.

92 rom both risk and non-risk groups, including young adults.

93 observed for different age groups (teenagers/young adults/seniors) without ozone.

94 strongly associated with migraine with aura, young age, female sex, use of oral contraceptives and sm

95 al history meeting the selection criteria of young (age <35 years) brother pairs admitted to the inte

96 , and in both the hippocampi and cortices of young (age 15-40 years old) and aged (40-65 years old) s

97 mary function of providing nutrition for the young, although recent studies have highlighted addition

98 Young and adult PV had both similar and distinct protein

99 Comparative proteomic analysis of EVs from young and aged astrocytes revealed peptide repertoires u

100 d host immune responses to hCoV infection in young and aged individuals.

101 thods and Results: We analyzed the aortas of young and aged normolipidemic wild type, disease-free mi

102 t transcript and protein across A1 layers in young and aged rats.

103 xamined the firing rates of CA3 neurons from young and aged, male, Long-Evans rats along the CA3 tran

104 though inflammatory onset is similar between young and elderly individuals, the resolution phase was

105 Both young and mature neurons migrate into compartments conta

106 t in the lysolecithin demyelination model in young and middle-aged mice, the latter group developed g

107 In summary, we report proteomic coverage of young and old mouse HSCs and progenitors, with broader i

108 rome coronavirus 2 (SARS-CoV-2) infection in young and old rhesus macaques, baboons and old marmosets

109 In both young and older adults, cognitive performance on a menta

110 em106b-/- mice, which was present already in young animals (21 days) and persisted until old age (23

111 rryover effects are particularly relevant in young animals, as early life stages are thought to be cr

112 ssed overall foveal structure in children as young as 5.8 years old by quantifying cone density and s

113 behavior in dynamic environments in rats as young as postnatal day 30.

114 found that extracellular vesicles (EVs) from young astrocyte were sufficient to convey support for ol

115 g mammals typically transfer energy to their young at extremely high rates while undergoing prolonged

116 Being young at the time of cancer treatment (relative risk [RR

117 netic resonance imaging studies suggest that young autistic children have alterations in white matter

118 oalveolar lavage was increased in old versus young baboons.

119 ication, supporting the idea that the use of young blood factors may be a useful strategy to expand a

120 ive effects in TAC were entirely mimicked in young CaMKIIdelta TG mice (6-8 weeks) where no overt car

121 rome and 258 sudden unexplained death in the young cases.

122 ge and adult CF patients, but not those from young CF patients, are outcompeted by the epidemic Bcc i

123 We evaluated the impact of an infant young child feeding (IYCF)-SQ-LNS intervention on anemia

124 In a young child with bilateral rapidly progressive vision lo

125 believe that properties were nonaccidental, young children (4 or 5 y) in this sample inferred the no

126 In this study, among 110 young children (mean age, 18 months) with linear growth

127 cal carriage was associated with exposure to young children (OR:2.71, 95%CI 1.51-5.02, p<0.001), and

128 acute lower respiratory infection (ALRI) in young children aged <5 years.

129 v viruses in young children, suggesting that young children are still at high risk to the newly emerg

130 that medical POHS replaced dental visits for young children enrolled in Medicaid and, in fact, offers

131 ng preventive oral health services (POHS) to young children in medical offices ("medical POHS").

132 outpatient cost of management of RSV-ALRI in young children to assist health policy makers in making

133 is a useful method for frequently monitoring young children with adrenal dysfunction or severe asthma

134 Young children with CAAP carrying common PnIST had a low

135 n Aspergillus infections and lung disease in young children with CF.Methods: Longitudinal data on 330

136 g immune phenotype was defined in adults and young children with early atopic dermatitis (AD), but ch

137 blet-based US was used to assess bone age in young children within their homes in rural Cotopaxi, Ecu

138 ausing acute respiratory tract infections in young children worldwide.

139 e examined the spatio-temporal complexity of young children's gaze patterns as they viewed stimuli va

140 es severe respiratory infections in infants, young children, and the elderly, and currently, no licen

141 ive antibodies (>=40) to A(H3N2)v viruses in young children, but induced higher antibodies to A(H3N2)

142 Otitis media (OM), a very common disease in young children, can result in hearing loss.

143 nknown aetiology that predominantly afflicts young children, causes coronary artery aneurysms and can

144 However, in very young children, lesions to either hemisphere are equally

145 y and extending this finding by showing that young children, older adults and people with dyslexia al

146 persons shedding virus in bodily secretions (young children, sexual activity, household crowding, low

147 bodies to 2010.1 cluster A(H3N2)v viruses in young children, suggesting that young children are still

148 Union in cereal-based foods for infants and young children, tea and herbal infusions.

149 f respiratory related hospital admissions in young children.

150 and mortality worldwide, particularly among young children.

151 It is accessible to young children.

152 ssociated with increased RSV-ARI severity in young children.

153 primary vaccine administered to infants and young children.

154 acute lower respiratory infection (ALRI) in young children.

155 s an important cause of severe infections in young children.

156 causes acute respiratory tract infections in young children.

157 thy salivary and dental plaque microbiome in young children.

158 al diversification rates, leading to dynamic young communities outside of the tropics, while relative

159 erfusion in Fontan patients (n = 5), healthy young controls (Fontan control, n = 5), patients with PA

160 Means and 2 SDs from young controls resulted in a lower threshold (1.33 SUVR)

161 challenges of severe pancreatic fibrosis and young donor age.

162 after middle cerebral artery occlusion using young donor biome (2-3 months) or aged biome (18-20 mont

163 ival of old cardiac allografts comparable to young donor organs.

164 living kidney donation (LKD), especially for young donors, has become a real matter of concern in the

165 rs have a crash rate nearly equal to that of young drivers whose crash rate is the highest among all

166 terial wall and in neocortical parenchyma of young, drug-resistant epilepsy patients (18-28 years old

167 set in determining the EEHV immune status of young elephants and responses to candidate EEHV vaccines

168 In this issue of Cell Host & Microbe, Young et al. shed light on dengue virus 3-specific epito

169 A transcription factor helps young flies to sleep longer by delaying the maturation o

170 OTUs covered 91% of the OTU readouts in the young group.

171 ty (p = 2.5x10-7) in brain images from 1,738 young healthy adults, providing insight into the lifetim

172 s using cerebellar brain inhibition (CBI) in young healthy female and male individuals.

173 mined the effect of 10 mg of baclofen, in 20 young healthy individuals, and found that the drug impai

174 uence learning and visuomotor learning in 20 young healthy participants of both sexes.

175 Young healthy subjects performed accurate cyclical force

176 upplement on cardiometabolic risk markers in young healthy Swedish children with fair and dark skin.

177 In 7 young healthy volunteers, 13 age-comparable healthy cont

178 underlying cause of sudden cardiac death in young individuals and result from mutations in several g

179 n Young Adults), a community-based cohort of young individuals followed over 30 years.

180 ighly lethal malignancy that mainly afflicts young individuals of African descent and is resistant to

181 iments that manipulated both CO(2) and P for young individuals of woody and non-woody species, we pre

182 h, the effect of AD-PRS on brain function in young individuals remains unknown.

183 the influenza-associated burden occurs among young infants and in low-income and lower middle-income

184 human metapneumovirus-associated ALRI among young infants in low-income and lower-middle-income coun

185 n impacted care of hospitalized neonates and young infants.

186 Award, American Society of Clinical Oncology Young Investigator Award, MSK's Ludwig Center, Weiss Fam

187 rtunities to advance the academic careers of young investigators while they strived to make contribut

188 syndrome and sudden unexplained death in the young is unknown.

189 T5 in BIA metabolism, occurring primarily in young leaves and embryos of sacred lotus.

190 on and demethylation of aberrantly expressed young LINE-1s in normal tissues.

191 Initiatives, such as the Saving Young Lives programme, to train local medical staff from

192 Young (<29 y) secondary grasslands were composed of weed

193 In this case series of 4 young male patients with severe COVID-19, rare putative

194 ker combinations were compared in 12 healthy young male rhesus monkeys (~1-2 y old, ~3 +/- 1 kg).

195 tness but also parts of anaerobic fitness in young males.

196 myopic ocular growth and its recovery in the young mammalian eye does not require an intact optic ner

197 (DMD) causes severe disability and death of young men because of progressive muscle degeneration agg

198 to +2 degrees C core temperature in healthy young men is not enough to confer a major oxidative and

199 the confirmation of this being a disease of young men.

200 carpal fractures and occur predominantly in young men.

201 Cardiac allografts in young mice (2-3 months) treated with CTLA4-Ig survived i

202 ctivation in primary somatosensory cortex of young mice and behavioral hyperactivity in the mice at o

203 e triggered acute hyperlipidemia in aged and young mice by inducing liver-specific degradation of the

204 vs. saline) or HF (~50% vs. saline) diet and young mice fed a HFD (~30%).

205 red IELps parked better in the intestines of young mice than in adults.

206 In young mice, both type A and type B IELps had an S1PR1+ a

207 We found that EphA4 KO in young mice, but not older adult mice, causes defects in

208 served reduced triacylglycerides in liver of young mice, caused by oxidative stress that activated FO

209 In healthy young mice, neither the ACE inhibitor ramipril nor the A

210 of Parkin in the aortas of aged mice but not young mice.

211 olian gerbils of either sex, divided between young, middle-aged, and old gerbils.

212 derly subjects that is distinct from that in young/middle-aged individuals, but also a novel set of t

213 y: n = 649; replication: n = 427) comprising young, minimally medicated patients with clinical high-r

214 oted premature HSC aging and inflammation in young miR-146a-null mice, preceding development of aging

215 Compared to infants born to young mothers aged 14-24 years who had no previous pregn

216 Fewer young mothers have experienced a child die, yet in many

217 Repeated pregnancy leaves young mothers nutritionally deprived which may in turn l

218 o had no previous pregnancies, those born to young mothers with repeated pregnancies have at least 0.

219 Unfortunately, due to the relatively young nature of the field and inherent incompatibility o

220 gions containing nonrandom concentrations of young (neo-) and old (paleo-) endemic taxa were identifi

221 essure of unknown cause, usually observed in young, obese women.

222 models of H(2) production and consumption in young oceanic crust.

223 ills, they would imply the presence of thick young oceanic lithosphere (20-25 km), and extremely hete

224 reduced form oxidases (NOXs) were studied in young/old mice on fast food diet (FFD).

225 Young-onset breast cancers (YOBC) tend to be aggressive

226 Furthermore, individuals with young-onset T2DM seem to have a higher risk of complicat

227 Carotid webs should be suspected in a young patient presenting with recurrent unihemispheric s

228 We had similar experience in a young patient with severe asthma treated with dupilumab.

229 Prognosis in young patients with breast cancer is generally poor, yet

230 tudy was to examine the prevalence of ODD in young patients with NA-AION.

231 t in the context of risk-adapted therapy for young patients with NRSTS.

232 ate the subgingival microbial composition of young patients with severe periodontitis treated with sc

233 important cause of myocardial infarction in young patients without traditional risk factors of ather

234 ce in Psychiatry Network (NSPN), a cohort of young people (aged 18-29 years) in the United Kingdom, w

235 A total of 478 young people (median, 9.3; range, 2-18 years) with physi

236 were identified between indicators of IDU in young people and youth unemployment, Gini coefficient, o

237 Young people engage poorly, even obstructively, with con

238 n antidepressant prescribing in children and young people in England and whether the drugs prescribed

239 escence as well as an unmet need for care in young people with psychotic disorders.

240 We argue that young people's capacity to encourage each other to obser

241 Investing in young people's education and training potential could re

242 which are a common cause of heart failure in young people, have increased during the last decades.

243 e highlighted priorities to consider for any young person with sickle cell disease transitioning from

244 Using an efficient child- and young person-centered approach, we developed 2 robust, a

245 or to 3 of the leading causes of death among young persons (aged 10-24 years): unintentional injuries

246 The young pig may, therefore, be a useful large animal model

247 Food allergy was induced in young pigs using two protocols.

248 In this study, we focused on young Psen1(LF) rats to determine potential early pathog

249 The highest percentage of young PWID resided in eastern Europe (43.4%, 95% UI 39.4

250 that formed before the gravitationally bound young radio pulsar.

251 d the rejection of allogeneic skin grafts in young RAG2(-/-) recipient mice.

252 binge EtOH treatment were more pronounced in young relative to older animals, negating our hypothesis

253 ly associated with reductions in MCAv(mean) (Young: rho = -0.31, P = 0.30; Older: rho = 0.06, P = 0.8

254 Because the gamma phase has a large Young's modulus (ca. 26 GPa), a force of 0.1 muN can be

255 Alterations of Young's modulus (YM) and Poisson's ratio (PR) in biologi

256 ment of the nanoMIP stiffness, with the mean Young's modulus measured by AFM passing from 17 +/- 6 kP

257 ysiological levels of mechanical resistance (Young's modulus of 4 kPa).

258 mechanics testing further confirmed that the Young's modulus of the adhesive increased by nearly 4 fo

259 e relaxed and contracted muscle cell and the Young's modulus of the matrix without further knowledge

260 In addition, the axial Young's modulus values derived from the persistence leng

261 The high Young's modulus, 20.3 MPa, and excellent photothermal pe

262 The Young's modulus, swelling ratio, acid uptake and digesti

263 Today, the commitment of young scientists to public service is at an all-time hig

264 omic battles over segregation are rampant on young sex chromosomes and utilize RNAi to defend the gen

265 In addition, we discovered that young skin recruited a significantly higher number of mo

266 e that promotes healthy skin regeneration in young skin.

267 n sources shifted from plant aboveground and young soil respiration to old soil respiration.

268 The brains of young songbirds develop motor circuits that achieve the

269 erent sensitivities to force, which we name "young/strong" and "old/weak." The "young/strong" state 1

270 we name "young/strong" and "old/weak." The "young/strong" state 1 has adenosine 5'-diphosphate (ADP)

271 d tracer uptake in these regions compared to young, tau-negative controls.

272 ng cause of diarrhea, especially in the very young, the elderly, and immunocompromised populations.

273 cle tissue was hypermethylated compared with young tissue, enriched for; pathways-in-cancer (includin

274 sential for the methylation and silencing of young transposable elements.

275 Young Trem2-/- mice exhibited normal cognitive function

276 foundation of normative ECG standards in the young utilizing Z-scores.

277 fferent age groups (~ 4-6 months, denoted as young versus ~ 2 years, denoted as adult) and studied th

278 , and olfactory stimulation delivered to the young via contact with the mother, and in some mammals,

279 d, parallel-group phase 1 study, 120 healthy young volunteers received either placebo or 1 of 3 doses

280 In young wildtype mice, rats, and NHPs, but not in M(1) mAC

281 In the simpler young wine model, V1 could be replaced by a vector conta

282 onsiderably higher than that predicted among young women (<30 years old).

283 g sex: 326 adolescents (15-19 years) and 696 young women (20-24 years), 31.7% (95% confidence interva

284 We obtained blood samples from 185 young women (average age 21.2) in two cohorts and tested

285 ish primary care, with additional impact for young women aged 20-24 years and those from deprived bac

286 risk for adverse imaging outcomes, including young women and children.

287 SCAD predominantly occurs in relatively young women and is an important cause of myocardial infa

288 ies reported poor post-partum outcomes among young women living with perinatal HIV infection who are

289 nfarction (AMI) is missed more frequently in young women than men, which may be related to the cognit

290 s a form of systolic heart failure affecting young women toward the end of pregnancy or in the months

291 fier) to discriminate between outcomes among young women with untreated CIN grade 2 (CIN2).

292 The Young Women's Breast Cancer Study is a prospective cohor

293 serodiscordant couples, adolescent girls and young women, female sex workers, and men who have sex wi

294 Our study suggests that, in young women, transseptal TMVI to treat failing bioprosth

295 contribute to decreased HIV incidence among young women.

296 and meeting the demand for contraception of young women.

297 of myocardial infarction (MI), typically in young women.

298 ficiency virus (HIV) in adolescent girls and young women.

299 reased dendritic spine density compared with young WT.

300 ibly hypoactive in distal CA3, compared with young (Y) rats.