ライフサイエンスコーパス: zona

1 e and cortical components and expressing the zona and functional markers of the original fetal organ.

2 opriate site on the sperm surface to mediate zona binding.

3 iffusion of cross-linked clusters containing zona-binding molecules and GM1 gangliosides in the plasm

4 ethyl-beta-cyclodextrin, clusters containing zona-binding molecules diffuse randomly over the acrosom

5 Initially, GM1 and zona-binding molecules localize to the apical ridge on t

6 novel lipid raft-like structures containing zona-binding molecules over the sperm acrosome.

7 Both GM1 gangliosides and zona-binding molecules partition into a low density Trit

8 ced coalescence of GM1 gangliosides (but not zona-binding molecules) suggestive of a specific mechano

9 dopaminergic neurons of the substantia nigra zona compacta.

10 resting membrane potential of bovine adrenal zona fasciculata (AZF) cells and function pivotally in t

11 Bovine adrenal zona fasciculata (AZF) cells express bTREK-1 K+ channels

12 Bovine adrenal zona fasciculata (AZF) cells express Ca(v)3.2 T-type Ca(

13 9.9 times higher in zona glomerulosa than in zona fasciculata (p=6.6 x 10(-24)).

14 he outer zona glomerulosa (zG) and the inner zona fasciculata (zF).

15 lomerulosa (ZG) and glucocorticoids by inner zona fasciculata (ZF).

16 ling cortisol-secreting cells of the adrenal zona fasciculata but are absent in a subset of APAs rese

17 ction of Cyp11b2 in glucocorticoid-producing zona fasciculata cells.

18 eta-catenin signaling pathway in a subset of zona fasciculata cells.

19 ced the number of steroidogenic cells in the zona fasciculata of the adrenal cortex.

20 omparing transcriptomes of zona glomerulosa, zona fasciculata, and tumour in human adrenal tissue, an

21 compared transcriptomes of zona glomerulosa, zona fasciculata, and tumour obtained by laser capture m

22 adrenocortical zones [zona glomerulosa (ZG), zona fasciculata, and zona reticularis].

23 rexpressed in zona glomerulosa compared with zona fasciculata.

24 However, sAC(-/-) sperm fertilize zona-free oocytes, indicating that gamete fusion does no

25 ceptors (AT(1)Rs), present in adrenocortical zona glomerulosa (AZG) cell membranes.

26 produced and secreted by the adrenocortical zona glomerulosa (AZG) cells after angiotensin II (AngII

27 ntial for production of aldosterone by outer zona glomerulosa (ZG) and glucocorticoids by inner zona

28 c layers that develop postnatally, the outer zona glomerulosa (zG) and the inner zona fasciculata (zF

29 Aldosterone-producing zona glomerulosa (zG) cells of the adrenal gland arrange

30 ances in determining the activation state of zona glomerulosa (zG) cells.

31 erproduction of aldosterone from the adrenal zona glomerulosa (ZG) is also the most frequent cause of

32 icoid aldosterone is produced in the adrenal zona glomerulosa (ZG) under the control of the renin-ang

33 tome with conventional adrenocortical zones [zona glomerulosa (ZG), zona fasciculata, and zona reticu

34 Zona glomerulosa (ZG)-like APAs frequently have mutation

35 Zona glomerulosa cells (ZG) of the adrenal gland constan

36 Here, we show zona glomerulosa cells in the adult adrenal cortex organ

37 at were at least five times overexpressed in zona glomerulosa compared with zona fasciculata.

38 ssociated with a pattern of decreased normal zona glomerulosa CYP11B2 expression and increased aldost

39 disruption of this signaling complex in the zona glomerulosa may provide a new therapeutic approach

40 is one of the most highly expressed genes in zona glomerulosa of the human adrenal gland.

41 s in situ and in cells of the native adrenal zona glomerulosa stimulated by Ang II in vivo.

42 ANO4 was 19.9 times higher in zona glomerulosa than in zona fasciculata (p=6.6 x 10(-2

43 k for studying the role of rosettes in adult zona glomerulosa tissue maintenance and function.

44 these adenomas, composed of cells resembling zona glomerulosa, have mutations in genes ATP1A1 and CAC

45 derstand whether the adenomas originate from zona glomerulosa, we carried out a microarray analysis c

46 roarray analysis comparing transcriptomes of zona glomerulosa, zona fasciculata, and tumour in human

47 Wycombe, UK), we compared transcriptomes of zona glomerulosa, zona fasciculata, and tumour obtained

48 We performed exome sequencing of ten zona glomerulosa-like APAs and identified nine with soma

49 One of the most zona glomerulosa-selective genes was ANO4, a member of t

50 e aldosterone-secreting cells of the adrenal zona glomerulosa.

51 ost cells and maintain the properties of the zona glomerulosa.

52 functional role of genes upregulated in the zona glomerulosa.

53 , and a glycan release model postulates that zona glycans are ligands for sperm.

54 s binding of acrosome-reacted spermatozoa to zona glycoproteins via a stereospecific polysulfate reco

55 go insufficient cortical granule release and zona-hardening, causing altered mechanics after fertiliz

56 neurons within the lateral hypothalamic area/zona incerta (LH) and the arcuate (Arc) nucleus.

57 imulated, with peak p values in superior STN/zona incerta (quantified bradykinesia), dorsal STN (mood

58 The subthalamic nucleus (STN) and the zona incerta (ZI) are two major structures of the subtha

59 e find that optogenetic stimulation of mouse zona incerta (ZI) gamma-aminobutyric acid (GABA) neurons

60 cleus (VPM), neurons of the ventral thalamus zona incerta (ZI) have been shown to exhibit multiwhiske

61 Zona incerta (ZI) is a largely inhibitory subthalamic re

62 We found that mouse zona incerta (ZI) projection neurons form a GABAergic ax

63 ith DBS of the ventro-oralis posterior (VOP)/zona incerta (ZI) region, and subsequently underwent bli

64 ear generalization could be modulated by the zona incerta (ZI), a subthalamic brain region that influ

65 on of activity in the GABAergic nucleus, the zona incerta (ZI), and concomitant increased activity in

66 ntrast, the ETI (arising from basal ganglia, zona incerta (ZI), anterior pretectum, and pontine retic

67 located in the lateral hypothalamus (LH) and zona incerta (ZI), but MCHR1 mRNA is widely expressed th

68 AAV-orexin gene delivery into neurons of the zona incerta (ZI), or the lateral hypothalamus (LH) bloc

69 was found in a circumscribed portion of the zona incerta (ZI)-a region assigned to the hypothalamus

70 ir neurons), midline raphe (26%), LHA (22%), zona incerta (ZI, 15%), CeA (5%), paraventricular nucleu

71 colliculus terminated densely in the ventral zona incerta (ZIv), but did not overlap the labeled neur

72 ensory cortex (SSp) to the ventral sector of zona incerta (ZIv).

73 by medial hypothalamic areas as well as the zona incerta and projected to specific forebrain areas s

74 periaqueductal gray, caudal portions of the zona incerta and subparafascicular nucleus, and the late

75 w images for differentiation of STN from the zona incerta and substantia nigra, respectively, and was

76 tion of Lhx6-positive neurons in the ventral zona incerta bidirectionally regulate sleep time in adul

77 roxylase-positive) neurons; however, <10% of zona incerta dopaminergic neurons (which are not hypophy

78 othalamic groups (A12, A14), the prethalamic zona incerta group (A13), the preoptic groups (A15), and

79 ld explain why deep brain stimulation of the zona incerta is beneficial to patients who suffer from P

80 polaris, posteromedial thalamic, and ventral zona incerta nuclei, are only weakly modulated by touch.

81 subsequently targeted the caudal part of the zona incerta nucleus (cZI).

82 By demonstrating that the zona incerta regulates communication between the superio

83 rgic subpopulation of neurons in the ventral zona incerta that promote sleep.

84 GCs, but not DRD4-DSGCs, also project to the zona incerta, a thalamic area not previously known to re

85 example, inhibition from the basal ganglia, zona incerta, and pretectal regions, and chemical modula

86 lamus, including the posterior thalamus, the zona incerta, and the anterior pretectum.

87 ocessing, including the superior colliculus, zona incerta, and the visual and retrosplenial cortices.

88 put to the superior colliculus (SC) from the zona incerta, as well as the organization of D1- and D2-

89 were with the claustrum, reticular nucleus, zona incerta, lateral posterior and medial pulvinar nucl

90 asalis of Meynert, medial habenular nucleus, zona incerta, neurosecretory arcuate nucleus, cranial mo

91 paraventricular and posterior hypothalamus, zona incerta, periaqueductal gray, intermediate layers o

92 iative thalamic nuclei, superior colliculus, zona incerta, pontine nucleus, multiple other brainstem

93 tical inhibition, we performed recordings in zona incerta, where 10, but not 40, Hz stimulation evoke

94 et of GABAergic neurons in the mouse ventral zona incerta, which express the LIM homeodomain factor L

95 input were mediated by GABA and activity in zona incerta.

96 ct to the caudate, the basis pontis, and the zona incerta.

97 he globus pallidus, subthalamic nucleus, and zona incerta.

98 sensory cortex, paraventricular nucleus, and zona incerta; no regions were higher in maternal mice.

99 ressive motility and are unable to fertilize zona-intact eggs.

100 that sperm ZP3R/sp56 is important for sperm-zona interactions during fertilization and support the c

101 f ZP2 and that binding at the surface of the zona is not sufficient to induce sperm acrosome exocytos

102 A defining characteristic of an essential zona ligand is sterility after genetic ablation.

103 d by Sonic hedgehog (Shh) signaling from the zona limitans intrathalamica (ZLI) at the rostral border

104 position the shh-positive signaling boundary zona limitans intrathalamica (ZLI) in the forebrain.

105 ecode a set of brain enhancers active in the zona limitans intrathalamica (zli), a signaling center e

106 The thalamic organizer is the zona limitans intrathalamica (ZLI), a transverse linear

107 alic signaling centers, the cortical hem and zona limitans intrathalamica (ZLI), are merged, oblitera

108 the ventral forebrain but maintained in the zona limitans intrathalamica (ZLI), the mid-diencephalic

109 the entire thalamic ventricular zone and the zona limitans intrathalamica (ZLI).

110 mus and an intervening boundary region - the zona limitans intrathalamica (ZLI).

111 y with putative signalling properties -- the zona limitans intrathalamica (ZLI).

112 ignalling centres-the anterior neural ridge, zona limitans intrathalamica and isthmic organizer-are p

113 embryo, including in a domain in or near the zona limitans intrathalamica.

114 mic eminence, and derivatives of the rostral zona limitans shell domain, respectively) were mapped ac

115 ndergo acrosome exocytosis and penetrate the zona matrix before gamete fusion.

116 tive mechanism in which penetration into the zona matrix initiates a mechanosensory signal transducti

117 to four postsynaptic density-95/discs large/zona occluden-1 (PDZ) domains of sodium-hydrogen exchang

118 -terminal postsynaptic density 95/disc-large/zona occludens (PDZ) binding domain increased its range

119 -terminal postsynaptic density 95/disc-large/zona occludens (PDZ) binding motif.

120 mediates interactions with PSD-95/disc large/zona occludens (PDZ) domain-containing proteins.

121 The first two PSD-95/disks large/zona occludens (PDZ) domains of PSD-95 have been shown t

122 BP50) are postsynaptic density 95/disc-large/zona occludens (PDZ)-domain-containing scaffolding prote

123 Zona occludens (ZO) proteins are molecular scaffolds loc

124 tabolite of arachidonic acid, by stimulating zona occludens (ZO)-2 tyrosine phosphorylation and its d

125 unction components [Occludin, Claudin-1, -2, Zona occludens (ZO-1, -2)].

126 te for the interaction of PSD-95/Discs Large/Zona Occludens 1 (PDZ) domain-containing proteins.

127 the GAT1 postsynaptic density 95/Discs large/zona occludens 1 (PDZ)-interacting domain.

128 ) and blood-brain barrier (BBB) occludin and zona occludens 1 (ZO-1) expression were significantly de

129 ulation of tight-junction-associated protein zona occludens 1 (ZO-1), translocation of ZO-1 to cell-c

130 cause cell elongation, and alter junctional zona occludens 1 and vascular endothelial-cadherin stain

131 ith PDZ (postsynaptic density 95/Discs large/zona occludens 1) protein PICK1 (protein interacting wit

132 ZO-1 (Zona occludens 1), encoded by the tight junction protein

133 ies as evidenced by staining for F-actin and zona occludens 1.

134 ment of the blood-brain barrier (claudin 5a, zona occludens 1a and b).

135 lls, silencing of the tight junction protein zona occludens 2 (ZO-2 KD) induces cell hypertrophy by t

136 Zona occludens 2 (ZO-2) has a dual localization.

137 NAs and protein for claudin-5, occludin, and zona occludens 2 were also reduced in infected cells.

138 ht junction proteins (claudin 1, 14, 16, and zona occludens 2), nine gap junction proteins (connexin

139 ents of inositol pentakisphosphate 2-kinase, zona occludens 3, and FAT tumor suppressor 2).

140 in granule-like cytoplasmic structures, and zona occludens 3.

141 lti-PDZ (postsynaptic density 95/discs large/zona occludens) domain AMPAR-binding protein, is bidirec

142 smic PDZ (postsynaptic density 95/disc large/zona occludens) protein that assembles macromolecular co

143 postsynaptic density-95 (PSD-95)/Discs large/zona occludens-1 (PDZ) binding domain, which is present

144 postsynaptic density-95 (PSD-95)/Discs large/zona occludens-1 (PDZ) binding motif, is localized to th

145 nsity protein of 95 kilodaltons, disc large, zona occludens-1 (PDZ) domain-containing proteins appear

146 ptor-mediated signals and PSD-95-discs large-zona occludens-1 (PDZ) domain-dependent signals are requ

147 t of two postsynaptic density 95/disks large/zona occludens-1 (PDZ) domains and a tail ending in an e

148 irst two postsynaptic density-95/Discs large/zona occludens-1 (PDZ) domains of the scaffolding protei

149 postsynaptic density-95 (PSD-95)/discs large/zona occludens-1 (PDZ) interaction to AMPA receptor (AMP

150 ntains a postsynaptic density-95/Discs large/zona occludens-1 (PDZ) ligand, which is absent in EAAT2a

151 cking a Postsynaptic density 95, Disk large, Zona occludens-1 (PDZ) motif.

152 rich and postsynaptic density-95/Discs large/zona occludens-1 (PDZ)] protein erbin and delta-catenin,

153 l microscopy using the tight junction marker zona occludens-1 (ZO-1) and end-binding protein-1 (EB-1)

154 naptic density-95 (PSD-95)/Discs large (Dlg)/zona occludens-1 (ZO-1)] binding domain and localizes to

155 naptic density-95 (PSD-95)/Discs large (Dlg)/zona occludens-1 (ZO-1)] interactions with members of th

156 phosphoprotein 50) is a PSD-95, disc large, zona occludens-1 adapter that acts as a scaffold for sig

157 Connexin43 (Cx43) and zona occludens-1 are improperly localized in Akap9 mutan

158 postsynaptic density protein-95/discs large/zona occludens-1 domain (PDZ).

159 he NHERF1 postsynaptic density 95/disc-large/zona occludens-1 domain.

160 ntaining PostSynaptic Density-95/Discs large/Zona Occludens-1 domains, is an ortholog of the Drosophi

161 in and podocyte dysfunction, as evidenced by zona occludens-1 translocation to the membrane.

162 (postsynaptic density-95)/Discs large/ZO-1 (zona occludens-1) (PDZ) domain-containing protein, erbin

163 VI PDZ (postsynaptic density 95, Disk large, Zona occludens-1) adaptor protein synectin was essential

164 t junction proteins (occludin, claudin-1 and zona occludens-1) are internalized through an NF-kappaB-

165 ugh PDZ (postsynaptic density-95/Discs large/zona occludens-1) binding domain interactions and trigge

166 the PDZ (postsynaptic density-95/Discs large/zona occludens-1) binding domain, which interacts with T

167 is PDZ (postsynaptic density-95/Discs large/zona occludens-1) domain independent and is regulated by

168 The PDZ (postsynaptic density-95/discs large/zona occludens-1) domain-based interactions play importa

169 93)/Chapsyn-110 is a PDZ (PSD-95/Discs large/zona occludens-1) domain-containing membrane-associated

170 the PDZ (postsynaptic density-95/Discs large/zona occludens-1) domain-containing protein interacting

171 g through two of its PDZ (PSD-95/Discs large/zona occludens-1) domains as well as intact N-terminal a

172 ization and the first two PDZ (PSD-95, Dlg1, zona occludens-1) domains, the PDZ3 and guanylate kinase

173 d a PDZ (postsynaptic density-95/Discs Large/zona occludens-1) scaffold protein, INAD (inactivation n

174 he induction of the tight-junction molecules zona occludens-1, claudin 3, and claudin 5 and other pat

175 imarily affected the tight junction proteins zona occludens-1, claudin-1, and claudin-5, which were s

176 9, substrates of matrix metalloproteinase-9 (zona occludens-1, laminin), tissue inhibitor of matrix m

177 The expression of tight junction proteins zona occludens-1, occludin, claudin-1, and claudin-4, as

178 e found reduced expression of E-cadherin and zona occludens-1, whereas collagen-I and alpha-smooth mu

179 nolayer integrity and tight junction protein zona occludens-1, while the result for cells infected wi

180 g to the postsynaptic density-95/Discs large/zona occludens-1-binding domain of PTEN.

181 tein laminin, and the tight junction protein zona occludens-1.

182 postsynaptic density-95 (PSD-95)/Discs large/zona occludens-1] domains of membrane-associated guanyla

183 the PDZ [postsynaptic density-95/Discs large/zona occludens-1]-domain containing protein, protein int

184 uses its PDZ-binding motif to interact with zona occludens-2 (ZO-2) protein, which promotes YAP's tr

185 LIN-10, a postsynaptic density 95/disc-large/zona occludens-domain containing protein: GLR-1 accumula

186 loss of tight junction proteins occludin and zona occludin- 1 (ZO-1).

187 pithelial resistance (R(T)), dissociation of zona occludins 1 (ZO-1) from the tight junction complex,

188 a restrictive function in abduction; and the zona orbicularis could be evaluated equally well in any

189 erm initiate fertilization by binding to the zona pellucida (mZP), the specialized extracellular matr

190 of the transient immunocontraceptive porcine zona pellucida (PZP), and found that repeated vaccinatio

191 with high K(+) or by addition of solubilized zona pellucida (sZP).

192 At fertilization, mouse sperm bind to the zona pellucida (which consists of glycoproteins ZP1, ZP2

193 Proteins harboring a zona pellucida (ZP) domain are prominent components of v

194 The zona pellucida (ZP) domain is a bipartite protein struct

195 ations; the Tecta(L1820F,G1824D/+) mouse for zona pellucida (ZP) domain mutations causing stable mid-

196 x, which contains chondroitin proteoglycans, Zona Pellucida (ZP) domain proteins, and other glycoprot

197 h includes a domain of eight cysteines and a zona pellucida (ZP) domain.

198 e involved directly in binding to the female zona pellucida (ZP) in a species-specific manner.

199 regulation of fertilization, including sperm-zona pellucida (ZP) interactions as well as the early ev

200 The zona pellucida (ZP) is an extracellular matrix that surr

201 strom resolution, comprised of the bipartite zona pellucida (ZP) module in a helical arrangement with

202 ge leading to conformational activation of a Zona Pellucida (ZP) polymerisation domain.

203 tilization the spermatozoon binds to the egg zona pellucida (ZP) via sperm receptor(s) and undergoes

204 expression of an antibody that binds to the zona pellucida (ZP), a glycoprotein matrix that surround

205 Zona pellucida (ZP), the extracellular matrix sheltering

206 r matrix coating of the oocyte, known as the zona pellucida (ZP).

207 pecies-specific binding activity for the egg zona pellucida (ZP).

208 At fertilization, spermatozoa bind to the zona pellucida (ZP1, ZP2, ZP3) surrounding ovulated mous

209 unction of CPEB after pachytene, we used the zona pellucida 3 (Zp3) promoter to generate transgenic m

210 t an analysis of the pattern of evolution of Zona Pellucida 3 (ZP3), a protein present on the avian e

211 ld-type mice, we have generated human ORMDL3 zona pellucida 3 Cre (hORMDL3(zp3-Cre)) mice that overex

212 Dot1l knockout in growing oocytes using the Zona pellucida 3-Cre (Zp3-Cre) transgenic mice.

213 t resulted in human sperm penetration of the zona pellucida and accumulation in the perivitelline spa

214 ted normal motility, and could penetrate the zona pellucida and bind to the oolemma.

215 oviducts causes premature degradation of the zona pellucida and embryo lysis, and wild-type embryos t

216 epare for the prospective penetration of the zona pellucida and fusion with the egg.

217 Acrosome reaction, binding to zona pellucida and fusion with the oolemma were lower in

218 vealed significant reductions in a subset of zona pellucida and lectin-type proteins between wild-typ

219 MII) oocytes exhibited irregularities of the zona pellucida and meiotic spindle.

220 ly embryo transduction protocols (removal of zona pellucida and subzonal microinjection).

221 ole of ZP2 in mediating sperm binding to the zona pellucida and support a model in which human sperm-

222 ctions between the cumulus cells outside the zona pellucida and the oocyte within.

223 ting that the changes that take place in the zona pellucida at fertilization affected the interaction

224 Zona pellucida binding protein 1 (ZPBP1), a spermatid an

225 , regulatory inhibitor subunit 1B (PPP1R1B), zona pellucida binding protein 2 (ZPBP2), and gasdermin

226 family of zinc finger 3 (AIOLOS; IKZF3) and zona pellucida binding protein 2 (ZPBP2).

227 6p21 (HLA-DQA1), 9p24 (IL33), and 17q12-q21 (zona pellucida binding protein 2 [ZPBP2]-gasdermin A [GS

228 The mouse zona pellucida consists of three glycoproteins that are

229 Rgs2(-/-) eggs also underwent premature zona pellucida conversion in vivo.

230 ases that were sufficient to cause premature zona pellucida conversion.

231 des a light-responsive and membrane-anchored Zona Pellucida domain protein that supports light-depend

232 ct structure and contained peptides from the zona pellucida domain, which is involved in cell differe

233 DYF-7 contain, respectively, zonadhesin and zona pellucida domains, and DYF-7 self-associates into m

234 e shotgun cell adhesion protein gene and the zona pellucida family transmembrane protein gene, CG1319

235 coproteins in this regard because only human zona pellucida glycoprotein 3 (ZP3) and bovine proopiome

236 eta1,3-galactosyltransferase 1 (C1galt1)(FF):zona pellucida glycoprotein 3 Cre (ZP3Cre)] and Control

237 Each zona pellucida glycoprotein is synthesized in growing oo

238 Zona pellucida glycoproteins are responsible for species

239 ndings and reveal novel functions for murine zona pellucida glycoproteins.

240 These embryos do not hatch from the zona pellucida in vitro, fail to grow in culture, and ex

241 The mouse zona pellucida is composed of three glycoproteins (ZP1,

242 In mice, the zona pellucida is composed of three glycoproteins, but t

243 crosomes indicates that sperm binding to the zona pellucida is not sufficient to induce acrosome exoc

244 Recently the zona pellucida like domain containing 1 protein (ZPLD1,

245 present in MVA and is incorporated into the zona pellucida matrix of transgenic mice.

246 en mutated to prevent incorporation into the zona pellucida matrix, complementing earlier studies ind

247 rane domain and assembled into the insoluble zona pellucida matrix.

248 Via its bipartite zona pellucida module (ZP-N/ZP-C), UMOD forms extracellu

249 that mediate recognition and binding to the zona pellucida of the egg are still not understood.

250 steps: sperm bind and penetrate through the zona pellucida of the egg, adhere to the egg plasma memb

251 ctivity interferes with sperm binding to the zona pellucida of the ovum.

252 Recombinant ZP3R/sp56 bound to the zona pellucida of unfertilized eggs but not to 2-cell em

253 hey do not acrosome-react in response to egg zona pellucida proteins and have reduced fertilizing abi

254 g genes encoding antifreeze glycoprotein and zona pellucida proteins, are highly expanded in the icef

255 However, the sperm proteins that recognise zona pellucida receptors remain contentious despite long

256 Sperm at the surface of the zona pellucida remained acrosome-intact for more than 2

257 metalloendopeptidase that cleaves ZP2 in the zona pellucida surrounding mouse eggs to prevent additio

258 rcome barriers and penetrate the cumulus and zona pellucida surrounding the egg.

259 The extracellular zona pellucida surrounds mammalian eggs and mediates tax

260 The extracellular zona pellucida surrounds ovulated eggs and mediates game

261 Specific binding of spermatozoa to the zona pellucida that surrounds mammalian eggs is a key st

262 at about 75-80% of the murine sperm bound to zona pellucida under well defined in vitro conditions is

263 n to the mammalian egg extracellular matrix (zona pellucida) to allow penetration of the egg coat.

264 To prevent polyspermy, the zona pellucida, a structure that surrounds mammalian egg

265 nteracts with the female reproductive tract, zona pellucida, and the oolemma.

266 ontact with the egg extracellular matrix, or zona pellucida, by the matrix glycoprotein ZP3.

267 In the absence of the zona pellucida, embryos lacking CTNNB1 undergo fission a

268 y a relatively thick extracellular coat, the zona pellucida, that plays vital roles during oogenesis,

269 o establish a tenacious association with the zona pellucida, yet they are capable of fertilization.

270 Many candidates have been proposed as zona pellucida-binding proteins.

271 es of capacitation, the ability to undergo a zona pellucida-evoked acrosome reaction, develops more s

272 Uromodulin is a zona pellucida-type protein essentially produced in the

273 mete recognition and penetration through the zona pellucida.

274 ion along the oviduct and penetration of the zona pellucida.

275 l contact between the sperm and the oocyte's zona pellucida.

276 are incapable of fusing with eggs that lack zona pellucida.

277 protein in the egg's extracellular coat, the zona pellucida.

278 ole in mediating the binding of sperm to the zona pellucida.

279 sperm binding and/or penetration through the zona pellucida.

280 ted the interaction of this protein with the zona pellucida.

281 ADAM2 with ADAM3 in sperm binding to the egg zona pellucida.

282 pigs and named for its binding to the oocyte zona pellucida.

283 rom these mutant mice cannot bind to the egg zona pellucida.

284 phic sperm with reduced ability to penetrate zona pellucida.

285 ire more thrust to penetrate the cumulus and zona pellucida.

286 acellular matrix of mouse eggs, known as the zona pellucida.

287 hrough the oocyte prior to assembly into the zona pellucida.

288 blocked hatching of the blastocysts from the zona pellucida.

289 ncrease in cAMP levels, hyperactivation, the zona pellucidae-induced acrosome reaction, and most impo

290 either alone or coexpressed with other human zona proteins.

291 arts with intact early blastocysts that upon zona removal can attach to the substrate and develop int

292 zona glomerulosa (ZG), zona fasciculata, and zona reticularis].

293 bthalamic nucleus (STN) and substantia nigra zona reticulata (SNR).

294 s derived from huZP2 rescue mice supports a ;zona scaffold' model of sperm-egg recognition in which i

295 mpaired in embryos covered by a ZP4-devoided zona, suggesting a defective ZP protective capacity in t

296 t retain acrosome reacted spermatozoa on the zona surface prior to penetration.

297 e test set, sensitivity ranged from 67% (rio zona) to 100% (soft) while specificity ranged from 71% (

298 The structural changes in the zona upon fertilization are driven by the exocytosis of

299 O-1 siRNA delivery inside the blastomeres of zona-weakened embryos using electroporation not only kno

300 erm injection, and who received AH which the zona were completely removed.