ライフサイエンスコーパス: zona glomerulosa

1 functional role of genes upregulated in the zona glomerulosa.

2 e aldosterone-secreting cells of the adrenal zona glomerulosa.

3 ost cells and maintain the properties of the zona glomerulosa.

4 y GNA11 mutations were found in hyperplastic zona glomerulosa adjacent to double-mutant APAs.

5 day) inhibits AT(1) binding in adrenal gland zona glomerulosa and kidney glomeruli.

6 ceptors (AT(1)Rs), present in adrenocortical zona glomerulosa (AZG) cell membranes.

7 produced and secreted by the adrenocortical zona glomerulosa (AZG) cells after angiotensin II (AngII

8 eptides on aldosterone generation in a human zona glomerulosa cell line, H295R.

9 nd TRPC5 in the human adrenocortical (HAC15) zona glomerulosa cell line.

10 Zona glomerulosa cells (ZG) of the adrenal gland constan

11 as accompanied by marked increase in adrenal zona glomerulosa cells and adrenal P450aldo mRNA.

12 Here, we show zona glomerulosa cells in the adult adrenal cortex organ

13 ransdifferentiation of beta-catenin-positive zona glomerulosa cells into fasciculata cells and sensit

14 In zona glomerulosa cells of the adrenal gland, angiotensin

15 inding of angiotensin II to its receptors in zona glomerulosa cells was demonstrated.

16 ts reproduced modulation observed in adrenal zona glomerulosa cells.

17 t and cell-attached patches from rat adrenal zona glomerulosa cells.

18 intracellular calcium concentrations in the zona glomerulosa compared to controls, but the frequency

19 at were at least five times overexpressed in zona glomerulosa compared with zona fasciculata.

20 ssociated with a pattern of decreased normal zona glomerulosa CYP11B2 expression and increased aldost

21 these adenomas, composed of cells resembling zona glomerulosa, have mutations in genes ATP1A1 and CAC

22 hesis and cells from most of the adult human zona glomerulosa is the likely driver of the mutational

23 We performed exome sequencing of ten zona glomerulosa-like APAs and identified nine with soma

24 disruption of this signaling complex in the zona glomerulosa may provide a new therapeutic approach

25 is one of the most highly expressed genes in zona glomerulosa of the human adrenal gland.

26 One of the most zona glomerulosa-selective genes was ANO4, a member of t

27 s in situ and in cells of the native adrenal zona glomerulosa stimulated by Ang II in vivo.

28 ANO4 was 19.9 times higher in zona glomerulosa than in zona fasciculata (p=6.6 x 10(-2

29 k for studying the role of rosettes in adult zona glomerulosa tissue maintenance and function.

30 derstand whether the adenomas originate from zona glomerulosa, we carried out a microarray analysis c

31 ntial for production of aldosterone by outer zona glomerulosa (ZG) and glucocorticoids by inner zona

32 c layers that develop postnatally, the outer zona glomerulosa (zG) and the inner zona fasciculata (zF

33 Aldosterone-producing zona glomerulosa (zG) cells of the adrenal gland arrange

34 nenolone, and progesterone in bovine adrenal zona glomerulosa (ZG) cells.

35 ances in determining the activation state of zona glomerulosa (zG) cells.

36 Human adrenal zona glomerulosa (ZG) expression of GJA1 (the main GJ pr

37 erproduction of aldosterone from the adrenal zona glomerulosa (ZG) is also the most frequent cause of

38 icoid aldosterone is produced in the adrenal zona glomerulosa (ZG) under the control of the renin-ang

39 tome with conventional adrenocortical zones [zona glomerulosa (ZG), zona fasciculata, and zona reticu

40 Zona glomerulosa (ZG)-like APAs frequently have mutation

41 tenance of the aldosterone-producing adrenal zona glomerulosa (zG).

42 roarray analysis comparing transcriptomes of zona glomerulosa, zona fasciculata, and tumour in human

43 Wycombe, UK), we compared transcriptomes of zona glomerulosa, zona fasciculata, and tumour obtained