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1 s identified 17 nonsynonymous coding variants, of which 1 located in SMAP1 and 3 in RIMS1, a member o
2 men in the cohort, a total of 4,952 men died, of which 1,637 men died from cardiovascular diseases (
3 of progression occurring after an initial CR, of which 10 (24%) were classified as target progressio
4 7%) LPs in 22 patients showed CSF discordance, of which 10 (6.1%) LPs in 9 patients represented CSF e
5 (74.8%) of 13 818 deaths occurred in hospital, of which 10 045 (97.1%) followed an emergency hospital
7 tium sample included 10,765 overlapping cases, of which 10,614 (98.6%) were matched to 16,111 nonover
8 cedures were undertaken over the study period, of which 1035 (1.64%) were in eyes with previous intra
10 A total of 4 439 518 patients were screened, of which 11 234 (0.3%) have glaucoma, 96 527 (2.2%) ha
12 The authors' search retrieved 1,986 studies, of which 11 met criteria for inclusion (6 RCTs and 5 p
13 e of 33 proteins were altered in both strains, of which 11 were identified as core FtsH substrate pro
15 ch identified 15 615 non-duplicate references, of which 113 were deemed potentially relevant and were
18 Sixteen targets and 42 suspects were detected, of which 12 and 17, respectively, were not identified
20 g of particulate matter from the water column, of which 12 kg would be absorbed into mussel digestive
22 e majority (90-99%) were assigned to Bacteria, of which 12% shared the highest sequence similarity wi
23 emic strokes, 369 occurred at age >/=80 years, of which 124 (33.6%) were in non-anticoagulated patien
24 ary information on 6 117 263 Swedish siblings, of which 13 442 had a clinical diagnosis of AS, was co
25 ients with infantile epileptic encephalopathy, of which 13 had severe neurodevelopmental impairment a
26 orts of radiopharmaceutical adverse reactions, of which 13 were considered invalid, primarily because
27 cient DNA dataset with a total of 180 samples, of which 130 are newly reported here, from the Neolith
29 and 9,212 private copy number variants (CNVs), of which 133,992 and 88 are de novo mutations (DNMs),
32 heterochronic quantitative trait loci (hQTLs), of which 15 mediate the forms of shoot growth and fou
34 e were 18 secondary or exploratory end points, of which 15 are reported in this article, including du
35 we constructed a cohort of 675,379 singletons, of which 15,014 children were born to asthmatic mother
36 es from the 249 subjects, 307(71.3%) were CPE, of which 154(50.2%) were blaKPC-positive, 97(31.6%) bl
37 w databases and update papers on 98 databases, of which 16 have not been previously featured in NAR A
40 n data from 49395 molecule entries (redundant), of which 16885 are unique molecules (non-redundant) f
41 h newly diagnosed GBM were initially enrolled, of which 17 patients were randomized to receive CMV pp
46 37.5, and 10.5%, respectively) were included, of which 184 patients (8.8%; GOLD stage I-IV: 5.1, 7.4
48 ntified 226 differentially expressed circRNAs, of which 189 were significantly upregulated and 37 wer
49 al of 83 volatiles was assigned in the purees, of which 19 were detected for the first time as papaya
50 ned 2923 rectal swabs from healthy volunteers, of which 19 were MCRPEC, and 1200 rectal swabs from pa
51 were diagnosed in women without an indication, of which 19% (n = 19)/0% (n = 0) were anorectal only.
52 study identified 51,078 patients with sepsis, of which, 19,742 received calcium channel blocker trea
54 CXRs were interpretable in 3587 (85%) cases, of which 1935 (54%) were abnormal (site range, 35%-64%
56 bic training sessions (duration 30-60 minutes), of which 2 to 3 sessions were combined with resistanc
59 The search strategy retrieved 180 records, of which 20 studies were included in the systematic re
63 d 224 somatic mutations throughout our cohort, of which 216 were coding mutations in known driver gen
64 paroscopic gastric band associated procedures, of which $224 million (47.6%) of the payments were for
65 tients with HCM, 304 (20%) had episodes of AF, of which 226 (74%) were confined to symptomatic paroxy
68 elevated in people with severe mental illness, of which 230 (0.24%) had HIV, 518 (0.53%) had HBV, and
70 1824 total hospitalizations at 4483 hospitals, of which 250 (5.6%) were major teaching, 894 (19.9%) w
71 We identified 811 abstracts for screening, of which 254 articles underwent full-text review and 9
73 Sequencing revealed 30 BAP1 variants in total, of which 27 were rare (ExAc allele frequency <0.002).
75 abase search retrieved 4,172 unique citations, of which 289 were reviewed, and 13 studies representin
76 olute difference in average beta-value > 0.15), of which 3,243 (66.8%) were hypomethylated in TDFs co
77 ontiguous regions (contigs) larger than 1 kbp, of which 3,761 are novel with little or no sequence ho
78 ation time was 11.2 (6.3) minutes per patient, of which 3.0 (1.8) minutes (27% of the examination tim
83 esented to our center during the study period, of which 32 (27 patients) met the inclusion criteria.
84 dentified 86 cases: 51 infants (59%) with NHS, of which 32 (67%) were idiopathic, 30 (35%) were hemor
86 showed 42 lesions not found on (68)Ga-DOTATOC, of which 33 were found to be true-positive on follow-u
91 t were differentially expressed after the LCD, of which 350 and 33 were associated with changes in bo
94 were screened between Feb 3 and Oct 10, 2016, of which 37 were randomly assigned and included in an
95 s of 1012 bulk and 430 single layer materials, of which 371 systems are common to bulk and single lay
97 ified arbuscule degeneration-associated genes, of which 38% are predicted to encode secreted hydrolas
101 genome-wide significant (P<5x10(-)(8)) for BP, of which 4 are new BP loci: rs9678851 (missense, SLC4A
102 th a target population of 100 000 individuals, of which 4.2% (95% CI 2.2-6.8) were estimated to be in
105 al of 64 enucleated group D eyes (62 patients), of which 40 (40 patients) were primary and 24 (22 pat
108 and August, 2013, to participate in the trial, of which 409 facilities were randomised for residents
109 nd genomes from 168 species in Caryophyllales, of which 43 transcriptomes were newly generated for th
113 ially expressed by over two-fold and p < 0.05, of which 46 genes were upregulated and 200 genes were
114 explained 79% of variation in flowering date, of which 46% could be assigned to plasticity and genet
115 d health reached nearly US$14 billion in 2013, of which 48% supported child health ($6.8 billion), 34
116 andomly assigned to the immunogenicity subset, of which 503 were included in the per-protocol set.
117 e platform had data from 3374 clinical trials, of which 537 (16%) evaluated cardiometabolic therapeut
118 ociated with CM-specific survival at P < 0.05, of which 547 SNPs were still considered noteworthy aft
119 radioallergosorbent test/ImmunoCAP performed, of which 57.3% had an IgE level of grade 3 or higher.
120 25 distinct VHH families binding trimeric Env, of which 6 neutralized heterologous primary isolates o
122 idence at ICU discharge was 10.3% (n = 96/933) of which 60.4% (n = 58/96) remained positive until hos
123 sequences were distributed among 90 proteins, of which 62 have not been previously implicated in zDH
124 tially expressed genes between the two groups, of which 62 were upregulated and 98 downregulated in c
125 e 86,797 documented episodes of vivax malaria, of which 62,492 (72.0%) were included in the analysis.
126 lgorithm identified 731 "possible AERD" cases, of which 638 were not in our AERD patient registry.
127 immunohistochemistry identified all the UHCA, of which 64.7% presented clinical bleeding manifestati
130 ) cefotaxime-resistant isolates were obtained, of which 66 and 12 displayed AmpC and ESBL phenotypes,
133 howed 26 lesions not found on (64)Cu-DOTATATE, of which 7 were found to be true-positive on follow-up
134 iagnosed after 789 481 screening examinations, of which 7.0% (91 of 1302) were detected among women w
135 tified 990 records from the literature search, of which 71 articles were assessed for eligibility aft
136 identified from TD and ASD sera respectively, of which 74 proteins were specially identified or up-r
137 ys with ICU length of stay more than 24 hours, of which 74,771 were ordered enteral nutrition within
138 itionally essential for GBS survival in blood, of which 75% were members of the capsular polysacchari
140 organic compounds (VOCs) from strain KM2501-1, of which 8 had contact nematicidal activity, 6 had fum
141 We identified 14 coding variants in 13 genes, of which 8 variants were in genes (ZBTB7B, ACHE, RAPGE
142 ive single nucleotide polymorphisms in-silico, of which 8,967 high value SNPs were incorporated into
143 at baseline or during the prophylaxis period, of which 83% were non-immune-mediated and 17% were imm
144 y, we found that 346 TSF sequences lack Pro-1, of which 85% are present in the malonate semialdehyde
145 patients were discharged directly from the ED, of which 87% received further medical prescriptions fo
146 concentration of carboxylic acids was 6.8 ppb, of which 87% was contributed by formic and lactic acid
147 21.8%) patients developed a biliary stricture, of which 88 (11.8%) exhibited intrahepatic structuring
148 cRNA loci required for robust cellular growth, of which 89% showed growth-modifying function exclusiv
150 Thirteen patients received MARS as a BTT, of which 9 were transplanted with a 1-year survival of
154 hors assessed 14,697 TTEs for appropriateness, of which 99% were classifiable using the 2011 AUC.
155 patients were included in the original trials, of which 995 had sufficient data to be included in our
156 dynamics at the synapse have been identified, of which a salient one is the postsynaptic actin stabi
158 d IPV to their immunization schedules, 46 (55%) of which adopted a schedule resulting in 3 injectable
159 had a deleterious germline mutation, 31 (3.5%) of which affected known familial pancreatic cancer su
160 Caenorhabditis elegans contains 25 Argonautes, of which, ALG-1 and ALG-2 are known to primarily inter
161 n additional 30 genes (MAGMA P < 2.73 x 10(-6)), of which all but one had not been implicated previou
162 identified in many Archaea and some Bacteria, of which all Archaea and most Bacteria also encode an
163 mental data with a more general network class, of which all previous topologies were special cases.
164 olites predicted 146 competitive OCT1 ligands, of which an endogenous neurotoxin, 1-benzyl-1,2,3,4-te
165 s remain high at $3.2 trillion spent annually, of which an estimated 30% is related to waste, ineffic
166 homas (13%), peripheral T-cell lymphomas (6.3%) of which angioimmunoblastic T-cell lymphomas (2.3%) w
169 aromatic molecular formulas were detected, 66% of which are included in a COO Kendrick mass defect (K
170 ncompass 11,735 distinct large SV sites, 38.1% of which are novel and 16.8% of which are balanced or
171 us, Moldova, Georgia, and Romania), 976 (75.1%) of which are multidrug or extensively drug resistant
172 Paspalum gene family including 30-60 members, of which at least eight are expressed at moderate leve
173 ficking) are enriched for regulatory variants, of which at least six (35%) alter transcription factor
176 ing toxin from the earthworm Eisenida foetida, of which both the soluble and membrane-inserted struct
177 explain 37% of father-to-son familial risk, 8% of which can be attributed to the 12 new signals repor
178 P) is a common acute abdominal disease, 10-20% of which can evolve into severe AP (SAP) causing signi
179 e the brain's information processing capacity, of which changes in functional connectivity may be a m
181 ely drug resistant and 38.2%, 51.9%, and 36.3% of which contain X-ray, computed tomography (CT) scan,
182 ately 1100 heat-sensitive HEK293 proteins, 12% of which could be isolated in complexes with sHsps.
183 levels in a murine microglial cell line (BV2), of which dimercaprol (2,3-dimercapto-1-propanol (DMP)
184 the site of high-risk atherosclerotic plaques, of which early detection and therapeutic stabilization
185 reatment or within 30 days of discontinuation, of which eight (3%) and five (2%) deaths were deemed r
187 that contain signature and tailoring enzymes, of which eight were characterized previously to be fun
188 d miRNA:target or tasiRNA:target interactions, of which eight were further confirmed with the RLM 5'-
189 (AEEEKKK) and EK2R1 (AEEEKRK)) both form SAHs, of which EK2R1 is more helical and thermo-stable sugge
190 romosomal DNA in TREX1-deficient neural cells, of which endogenous Long Interspersed Element-1 retrot
191 tegies in current clinical imaging guidelines, of which European ones primarily recommend CXR/MRI, wh
192 ding in macrophages and DCs, approximately 60% of which expressed inducible nitric oxide synthase (iN
194 hod uncovers ten genome-wide significant loci, of which five are novel (IGH, ELL2, HLA-B-C, AZI1, FUT
195 spond to 492 Arabidopsis orthologues, over 90% of which form a coherent protein-protein interaction (
196 or their likelihood of causing DILI in humans, of which >700 drugs were classified into three categor
197 dited miRNAs showed increased stability, 72.7% of which had DeltaDeltaG values less than -6.0 Kcal/mo
199 fied eight novel interaction partners of EGFR, of which half strongly interacted with oncogenic, hype
201 sources is threatened by noxious contaminants, of which heavy metals represents an area of growing co
202 L1 [Ensembl ENSG00000166535]) were identified, of which higher expressions were associated with slowe
204 have been shown to bind to several receptors, of which intercellular adhesion molecule 1 (ICAM-1) up
205 ecently reported a series of (+/-)MOD analogs, of which JJC8-016 (N-(2-((bis(4-fluorophenyl)methyl)th
206 ent of studies reported controlling outbreaks, of which just more than one-third eliminated the organ
207 total of 234 different species were consumed, of which <30% were consumed in more than one country.
209 stic mechanisms of a complex compound mixture (of which many are yet unidentified) rather than by sin
210 pre-mRNA splicing of a large number of genes, of which many are involved in regulating light signali
211 r transition metal cyclopentadienyl complexes, of which many have been used as catalysts for organic
214 -causing genes (BBS1-19) have been identified, of which mutations in BBS1 are most common in North Am
215 A regulon also included eight non-coding RNAs, of which Ncr1071, Syr6 and NsiR7 were experimentally v
217 ngle nucleotide polymorphisms were replicated, of which nine were associated with skin colour at geno
218 ns with a domain of unknown function (DUF3237), of which no member has a previously verified function
219 re were 37 deaths during the follow-up period, of which none were due to hepatitis B recurrence.
221 patients (2%) in the physician's choice group (of which one was judged to be treatment related) and n
222 mut group and seven [3%] in the control group), of which one-a pulmonary embolism in a 64-year-old ma
223 rol in vivo and conserves QS regulatory genes, of which one can complement a T. brucei QS signal-blin
225 176 distinct biosynthetic gene clusters (BGCs) of which only 24 have been linked to their products.
227 d bZIP binding to 156 disease associated SNPs, of which only 20 were previously annotated with known
228 ation of 12 anatomical variants in 8 patients, of which only 7 were correctly reported by the radiolo
229 of a highly heterogeneous population of cells, of which only a small subset of stem-like cells posses
230 curs in two distinct antigenic forms, D and C, of which only the D form elicits a robust neutralizing
232 ied to NaOH/EDTA extracts of a grassland soil, of which paramagnetic contaminations were removed with
233 s contributed a total of 1058 visits, 67 (6.3%) of which preceded new-onset BPSD within the next 5 ye
234 ycin-resistant (RIF(R) ) TB, approximately 41% of which results from the RpoB S531L mutation in RNA p
235 uld be achieved in the second cycle, with 75% of which retained after 100 cycles, which corresponds
236 were positive for at least one microorganism, of which RSV was the most common virus (41.0%), with a
237 hos, dppp, DPEphos, and Xantphos are screened, of which Ru1 and Ru4 are found to be the most active.
238 us (Ser(256), Ser(261), Ser(264), and Thr(269)), of which Ser(256) is crucial and sufficient for AQP2
240 ntially expressed (false discovery rate <0.05), of which seven genes replicated in both directionalit
241 olic compounds was found in the pistachio oil, of which seven compounds were reported for the first t
242 95 people died in the safety analysis set, of which seven deaths were judged possibly or probably
243 and health in animals, but evidence in humans, of which sex-specific effects on pubertal development
244 en patients (38%) experienced bleeding events, of which six (16%) were associated with fatal outcomes
247 ic acid (ACEPC) competitive GluN2 antagonists, of which ST3 has a binding affinity of 52 nM at GluN1/
249 increasingly being applied to animal networks, of which stochastic actor-oriented models (SAOMs) are
250 well as a bridging aza-dithiolate ligand (ADT) of which the amine moiety serves as a proton shuttle b
251 precursor protein (APP) matrix approach (AMA), of which the ACH has held a dominant position for ove
252 s the linear ubiquitin chain assembly complex, of which the catalytic core component is heme-oxidized
253 dary metabolites including phenolic compounds, of which the coumarin scopoletin (7-hydroxy-6-methoxy-
254 s result from a combination of two mechanisms, of which the first prevents multiple transposition bur
255 odifications (acyl-PTMs) have been discovered, of which the functional significance is still under in
256 iversification across plant lineages on earth, of which the genus Espeletia (Asteraceae) is a prime e
258 hermal hyperalgesia, and mechanical allodynia, of which the latter is completely dependent on puriner
259 We discuss possible routes of entry to Africa, of which the likeliest is adults and/or egg masses tra
260 Bacteroides spp. encode over 100 SusCD pairs, of which the majority have unknown functions and subst
261 better understanding perinatal brain injuries, of which the most common etiologies are hypoxia and is
262 s of triazole bisphosphonate GGDPS inhibitors, of which the most potent was a 3:1 mixture of homogera
263 range of hydroxycinnamate-derived metabolites, of which the most prominent accumulation (over 8,500-f
264 e set of methoxybenzothiophene-2-carboxamides, of which the N-benzylated derivative showed enhanced C
265 ed such studies to sufficiently flexible rods, of which the persistence length ([Formula: see text])
266 ral isotopic shifts of the phenylalanine band, of which the positions correlate well with a computati
267 la roots guided the isolation of 21 compounds, of which the structures were elucidated by 1D- and 2D-
268 xpression of any number of phosphodiesterases (of which there are 24 genes plus spice variants).
270 nine (2%) in the trastuzumab emtansine group (of which three were judged to be treatment related).
271 plicated by pregnancy-associated aHUS (p-aHUS), of which three appeared to be provoked by infection,
273 iated markers in a larger sample of C. gomesi, of which three localised to the W chromosome, thereby
274 gene transfer depends on a number of factors, of which tissue tropism is among the most important.
275 entres had a significant net loss of patients, of which two (5%) were established robotic centres and
276 selected for follow-up functional evaluation, of which two belonged to the TPS-c, three to the TPS-e
277 80 serious adverse events were identified, of which two were judged to be related to vaccination
278 ation is embedded in international food trade, of which two-thirds are exported by Pakistan, the USA
279 cantly modulated 44% of hypoxia-induced genes, of which two-thirds were downregulated including CA9 a
282 85%) had associated cardiovascular anomalies, of which ventricular septal defects (22/47, 47%), atri
285 otal, the CV encompasses 15% of CA, 8415 km(2) of which was identified as potentially land-sparing fo
287 eaving 8378 (82%) after removal of duplicates, of which we reviewed 54 (26 [48%] were quantitative de
293 four livers from donors >70, approximately 40% of which were used in 2 regions: 2 (520/3104) and 9 (6
294 women with 1727 diagnoses of ADH, 1058 (61.3%) of which were diagnosed by core biopsy and 635 (36.8%
298 inotuzumab ozogamicin group (22 [13%]; 18 [82%] of which were grade 3 or worse) than in the standard
299 as calculated between 47 regions of interests, of which whole-brain and region-specific means were co
300 discounted), avert 25% of HIV infections (42% of which would be directly because of PrEP), and lead
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