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1 xtracellular HSV-1 by 24 h postinfection (hpi), suggesting a unique neuronal response to viral infect
3 ONSA persist after parenteral corticosteroids, suggesting a component of corticosteroid nonresponsive
4 during neuronal differentiation of P19 cells, suggesting a conserved role of this kinase in the epig
5 rization of longer polySia chains on SynCAM 1, suggesting a critical role for polyST autopolysialylat
6 nked to metachondromatosis in humans and mice, suggesting a crucial role for SHP2 in the skeleton.
7 striatopallidal knock-out to wild-type levels, suggesting a dependence on adenosine receptor activity
8 levels of type I interferon (IFN-I) in lupus, suggesting a direct link between reduced CD11b activit
9 1 signaling rather than direct ligand sensing, suggesting a form of quorum sensing among neutrophils.
11 examinations (TBSE) were found to have MBAITs, suggesting a high penetrance in patients who have unde
12 ion covers a wide CCS range for the same mass, suggesting a large structural diversity of these drugs
13 tion is less frequent for noncoding sequences, suggesting a larger role of splicing coordination in s
14 rexpressing mutant, but not wild-type, PDGFRA, suggesting a mechanism through which the oncogenic act
15 ffector of cytokine-induced IKKbeta signaling, suggesting a mechanism through which the tumor microen
16 ubiquitin ligase antagonizes drebrin function, suggesting a model for control of the microtubule-acto
17 strongly modulated by vibrational excitation, suggesting a new avenue for active control over molecu
18 1 differentiation in the presence of TGF-beta, suggesting a novel approach to adoptive cell therapy.
19 response and myofibroblast formation in vivo, suggesting a novel therapeutic approach with p38 inhib
20 th inhibitory effects against colon carcinoma, suggesting a nutraceutical potential in the fight agai
21 ed in immediate relapse of status epilepticus, suggesting a pivotal role of deep brain stimulation in
22 tion in both non-diabetic and diabetic islets, suggesting a positive role of linagliptin in modulatin
24 ization can be modulated by ultraviolet light, suggesting a potential role for EAF2 in androgen regul
25 is allosterically regulated by InsP6 binding, suggesting a previously unidentified role of the eukar
26 ap, but only for the lower-frequency category, suggesting a prioritization of weakly learned informat
28 mental periodontal inflammation and bone loss, suggesting a promising platform for the development of
29 y and synergy during information transmission, suggesting a rationale for the regulation of these inf
30 h the c-src inhibitor PP2 rescued this effect, suggesting a role for GCs in promoting c-src-mediated
31 ted and uninfected bystander cortical neurons, suggesting a role for paracrine factors in induction o
32 h uninfected and HIV-infected human monocytes, suggesting a role for sPrP(c) in monocyte recruitment
33 seudomonas aeruginosa urinary tract infection, suggesting a role for urinary antimicrobial peptides i
35 icited suppression of early B and pro-B cells, suggesting a role of AHR in regulating B lymphopoiesis
38 atory nitrate reduction and sulfate reduction, suggesting a significant effect of local oxygenic phot
39 ar within than between these groups of plants, suggesting a specific association pattern according to
40 recovery to support normal balance behaviors, suggesting a therapeutic benefit to balance with ASO-2
41 and unique space in the CCS-mass 2D spectrum, suggesting a tight structure-function relationship for
43 cted kinetic fractionation of meteoric waters, suggesting a volcanogenic influence on the formation w
44 ing but lack activating Wnt-pathway mutations, suggesting activation by autocrine Wnt ligands and/or
45 on after starting antiretroviral therapy (ART), suggesting an immune reconstitution-like syndrome.
46 highest in fruits (up to 2.5) and leaves (0.5), suggesting an intensive transformation of CBZ in thes
49 ABHD5, impeded the proliferation and invasion, suggesting an ATGL-independent role of ABHD5 in modula
51 sociated with organism growth and development, suggesting an important role for synonymous codon usag
52 HCCs) develop in fibrotic or cirrhotic livers, suggesting an important role of liver fibrosis in the
53 ther somatic mutations or mRNA downregulation, suggesting an important tumour suppressor function.
56 the corpus callosum connecting these regions, suggesting an involvement of interhemispheric interact
57 ble by intrathecal administration of naloxone, suggesting an opioid-mediated mechanism; pharmacologic
58 ginal membrane regardless of alginate fouling, suggesting an ultimate solution to eliminating the irr
60 we found region-specific effects of each drug, suggesting both common and unique effects of imipramin
62 enome) of HSV(chol) and HSV(des) were similar, suggesting cholesterol and desmosterol in the HSV enve
64 y increasing concentrations of actin monomers, suggesting competition between actin and microtubules
66 sistent with a diagnosis of pseudoprotanomaly, suggesting decreased effective optical density of the
68 f the MEP and MVA pathways remained unchanged, suggesting divergent sites of synthesis for dominating
69 had seizures in their last year of follow-up, suggesting enduring seizure control was not regained b
70 plained by decarboxylated osteocalcin changes, suggesting existence of other osteokines that are unde
71 e higher frequencies of somatic hypermutation, suggesting extensive and serial rounds of clonal expan
72 s overexpressed in these FLI1-deficient iMegs, suggesting FLI1 negatively regulates ETS1 in megakaryo
74 ificant changepoints in all sites and proxies, suggesting fundamental and widespread changes in the t
75 otemporal transmission of glial tau pathology, suggesting glial tau transmission contributes to the p
77 substrate, and is reversed by RhoA inhibition, suggesting increased RhoA as an important mechanism.
78 tic radiation partially mediates visual delay, suggesting increased transmission time, whereas grey m
79 in healthy carriers nor at the species-level, suggesting infection-associated, short-term, within-ho
80 ed by H3K4me1, Ep300, and Fox/Sox/Smad motifs, suggesting interplay between these factors in gene reg
81 esent in separated genes in fungi and animals, suggesting its emergence as a result of domain shuffli
85 ed with the number of rival males in the pool, suggesting mechanisms selecting for consistent differe
86 ut not sufficient to increase ANO1 expression, suggesting methylation of positively correlated CpG's
87 lopment, wound healing, and even tumor growth, suggesting more complex physiological roles than curre
88 observed a reduction in cumulative tumor load, suggesting most benefit to be gained by early conversi
89 F4 gene target, was increased by asparaginase, suggesting mTORC1 inhibition during asparaginase expos
90 +) T cells and T cells treated with rapamycin, suggesting mTORC1 signaling controls their phosphoryla
92 hesis of one RNA molecule across Pol II genes, suggesting multiple rounds of pre-initiation complex a
93 maticity and unconventional superconductivity, suggesting nematicity to be common among correlated ma
94 nificantly moderates aggression between nests, suggesting nests are more related where there is more
98 eversed by overexpression of PcG member BMI-1, suggesting opposing roles for PEITC and PcG proteins i
99 pulmonary, but not in nonpulmonary, LCH cases, suggesting organ-specific contribution of oncogenic RA
100 r at least 6 years, and induced immune memory, suggesting possible protection against HPV vaccine typ
101 , have distinctly different cytokine profiles, suggesting potential differences in disease pathogenes
102 d expression of mammalian target of rapamycin, suggesting reduced amino acid catabolism in MS patient
104 and chromosomal shattering were also observed, suggesting replication stress as a root causative fact
105 of TLR7 partially attenuated this expression, suggesting roles for TLR7/8 in induction of fibrocytes
106 Africa that differ from the European genepool, suggesting separate evolutionary and breeding history.
108 ered cortical myo-inositol and glycine levels, suggesting sleep loss-induced modifications downstream
109 te removing less total tau by immunodepletion, suggesting specific interactions with species involved
110 agocytosis are normal in the absence of STIM2, suggesting STIM1 is the dominant calcium sensor requir
113 h(2)SNP of anorexia nervosa was 0.20 (SE=0.02), suggesting that a substantial fraction of the twin-ba
114 n response to drawdown (R(2) = 0.84, p < 0.01), suggesting that eutrophication magnifies the effect o
115 tion if turned upside down (self-righting, SR), suggesting that other miRNAs might also be involved i
116 gulated following traumatic brain injury (TBI), suggesting that stimulation of BDNF signaling pathway
117 sphatidylinositol 3,4-bisphosphate (PI(3,4)P2), suggesting that the macropinosome is the location whe
118 in complete neutralization of the input virus, suggesting that a fraction of virus particles are resi
119 stable across task-engaged and resting states, suggesting that abstract context representations are c
120 minus, adjacent to Lys-71, which binds to ATP, suggesting that acetylation status of Lys-72 may affec
121 psaicin-activated current was greatly reduced, suggesting that activation of adrenergic receptors in
122 ional ATM is still compatible with early life, suggesting that adaptation mechanisms contributing to
123 ro is not the main driver of this association, suggesting that additional properties of the transmitt
124 DR5 promoter fails to fully rescue lfs plants, suggesting that additional, auxin-independent regulati
125 for the interannual variability of wind power, suggesting that advances in long-term forecasting coul
126 but AcuIs have very high substrate affinities, suggesting that an effective detoxification system for
127 ht selectively impact viral protein synthesis, suggesting that an NP-mediated translation strategy is
128 ers surrounding the meiocytes and microspores, suggesting that appropriate GA signaling in the somati
129 +) compared with the dephosphorylated protein, suggesting that autophosphorylation functions to prime
130 ng at environmentally relevant concentrations, suggesting that bacteria likely regulate choanoflagell
131 member, human resistin, was also bactericidal, suggesting that bactericidal activity is a conserved f
132 that triggered by gga-miR-219b overexpression, suggesting that BCL11B was a stimulative regulator of
133 observed in the pancreata of cadaveric donors, suggesting that beta-cells are prone to attract CCR2(+
134 the typical signature of a late stage biofilm, suggesting that biofilm formation is severely hampered
135 pendent cellular degradation of collagen film, suggesting that cell-surface collagen degradation by M
136 ing PD-1 can recognize autologous tumor cells, suggesting that cells derived from PD-1(+) TILs can be
137 ning or adiposity in male or female offspring, suggesting that changes in the F1 generation were rela
138 nriched after pulldown of endogenous CircPVT1, suggesting that CircPVT1 might selectively modulate le
139 bly of anillin patches was myosin independent, suggesting that CSNK-1 prevents expulsion of the entir
140 portion had neuropathological evidence of CTE, suggesting that CTE may be related to prior participat
142 in the VtE-induced amelioration of DN in vivo, suggesting that DGKalpha is an attractive therapeutic
143 ons after hospital case mix was accounted for, suggesting that differences in hospital quality may on
144 demonstrate a defect in glomerular refinement, suggesting that distinct genes or sets of genes underl
145 (up to +81%) and xylose (up to +153%) release, suggesting that down-regulating CAD1 is a promising st
146 cid transporter 3 (EAAT3) blocks potentiation, suggesting that EAAT3 internalization increases extrac
147 plexes, enhancers and promoters, respectively, suggesting that each complex has distinct functions th
148 by both the nuclear and chromatophore genomes, suggesting that EGT in Paulinella chromatophora is ong
149 tations also increased the DNA unwinding rate, suggesting that electrostatic contacts with the exclud
150 ly to yield alkalinity/DIC ratios less than 1, suggesting that enhanced sulfide oxidation as a result
151 ciated with long-range chromatin interactions, suggesting that enhancers can influence the pause-init
152 fection, enteroendocrine cells are permissive, suggesting that enteroviruses infect specific cell pop
153 read at all sites was spatially heterogeneous, suggesting that environmental heterogeneity will affec
154 ficacy of standard curcumin remained constant, suggesting that ETO-curcumin may provide superior anti
155 sing PEX1 in wild-type plants impaired growth, suggesting that excessive PEX1 can be detrimental.
156 negative delta(13)C and delta(18)O anomalies, suggesting that explosive reactions between magma and
157 different combinations of cross-modal feature, suggesting that featural similarity of cross-modal sig
158 tors had no effect on evoked dopamine release, suggesting that feedback inhibition of acetylcholine r
159 show a loss of ITCs at postnatal time points, suggesting that Foxp2 may function downstream of Tshz1
160 results were verified by immunohistochemistry, suggesting that GalNAc-T6 plays a role in colon carcin
161 /J mice with sensitive high-frequency hearing, suggesting that gap junctions contribute to passive co
162 s appeared more balanced within each serotype, suggesting that genotype-level heterogeneity may be li
163 of GMAP6 protected Huh-7 cells from apoptosis, suggesting that GIMAP6 is an anti-apoptotic protein.
164 of presynaptic terminals and dendritic spines, suggesting that glutamatergic neurotransmission is unn
165 by the antioxidants glutathione and catalase, suggesting that HDM-induced reactive oxygen and nitrog
166 used no significant changes in wild-type mice, suggesting that Hjv is not a limiting factor for hepci
167 is associated with increased MyoD expression, suggesting that Hmox1(-/-) SCs are shifted toward more
168 th height in a cohort of 227 healthy children, suggesting that HOXA4 may play a role in regulating hu
169 exclusively to the dimeric form of the toxin, suggesting that human B cells recognize epitopes on th
170 measured indoors correlated to CO2 in daytime, suggesting that human occupants may contribute to thei
171 change upon the wetting-dewetting transition, suggesting that hydration-induced microscopic plasmoni
172 tion, and guanylation of U6 and Y RNA 3' ends, suggesting that in mammalian cells, the formation of a
173 nt increase in their blood OXT concentrations, suggesting that increased endogenous OXT secretion may
174 d by only a mild aggravation of tau pathology, suggesting that increased tau burden cannot fully acco
175 ich matched the stimulation of photosynthesis, suggesting that increases in photosynthesis are direct
176 colored objects compared with natural objects, suggesting that industrialization promotes color usefu
177 mportant implications for healthcare policies, suggesting that inequalities can be tackled with appro
178 RNAi lines accumulated the same intermediate, suggesting that inhibition of Fe-S cluster synthesis i
179 timulate beta-catenin-dependent transcription, suggesting that interactions between ORF2 and a comple
180 ormation, it is required for virion formation, suggesting that interactions of the N domain with cogn
181 was sensitive to high concentrations of EGTA, suggesting that intracellular Ca(2+) buffers play an i
182 ilar to those elicited by an increase of cGMP, suggesting that intradisulfide formation is associated
183 lated IPs in a catalytically competent manner, suggesting that IP hydrolysis has a role in plant path
184 ing the vegetative-to-reproductive transition, suggesting that is most active and key for Bailinggu d
185 insert stability can be achieved in sugarcane, suggesting that it is highly probable that transgenic
186 horylation and growth in a melanoma cell line, suggesting that it may provide a highly selective inhi
188 over 1 V is recorded in photovoltaic devices, suggesting that ITCC has great potential for applicati
189 observed DIP release from ATP into the medium, suggesting that K. mikimotoi cells were expressing ext
190 period before the onset of the summer monsoon, suggesting that local land-atmosphere feedbacks involv
191 co has substantially lower SES than Antioquia, suggesting that low SES in Choco serves as a protectiv
192 rations lower than the MTD are as efficacious, suggesting that lowering the total amount of drug admi
193 the ability to acutely respond to cold stress, suggesting that LP-induced increases in FGF21 impact m
194 , and late flowering was partially suppressed, suggesting that LTM functions to suppress SP in the ve
195 s independently of their chromosomal location, suggesting that microenvironments are highly different
196 nfiltrating, miR-155-deficient CD8(+) T cells, suggesting that miR-155 and ICB regulate overlapping p
197 MKK4/MKK5 also results in the same phenotypes, suggesting that MKK4/MKK5 might act upstream of MPK6 i
198 role of GRP78 in reducing prion pathogenesis, suggesting that modulating its levels/activity may off
199 e correlation with 2040 metabolites in common, suggesting that mouse models can be used to interrogat
201 n mimicked a Notch gain-of-function phenotype, suggesting that Myt1l allows newborn neurons to escape
202 es and can even be polymorphic within species, suggesting that nascent sex chromosomes arise frequent
203 -immunoprecipitation between Nedd4L and NKCC1, suggesting that Nedd4L indirectly suppresses NKCC1 exp
204 B pathway aberrations and LMP1-overexpression, suggesting that NF-kappaB activation is selected for b
205 s did not increase following RG-101 injection, suggesting that NK cells, but not HCV adaptive immunit
206 ted in additive effects on CCC1 transcription, suggesting that other activators contribute to the reg
207 are nearly identical between thymus and blood, suggesting that our analysis mainly detects selection
208 43 was specifically recruited to the nucleoli, suggesting that p-T153/Y155 regulates a previously una
209 tudy was higher compared to previous research, suggesting that patients exposed to unnecessary radiat
210 ociated with hospitalization while waitlisted, suggesting that personal, health system, and geographi
211 ticularly low levels of sucrose were observed, suggesting that plant sanctions affect carbon supply t
212 d the greatest compatibility with human blood, suggesting that pre-transplant perfusion of geneticall
213 ectively, in the Q-binding site, respectively, suggesting that release of the Q toward the membrane i
214 e activation, cell death, and IL-18 secretion, suggesting that restoring mitophagy and inhibiting inf
215 g IgPro20 were efficacious and well tolerated, suggesting that SCIg can be used as a maintenance trea
216 ons disappeared when lights were extinguished, suggesting that selective removal of light during nigh
217 d GLP-1 analog, to reduce body weight in rats, suggesting that serotonin is a critical mediator of th
218 omoter activity of autoinducer synthase genes, suggesting that some of the isogenic cells in a popula
219 g infection by fine-tuning NF-kappaB activity, suggesting that SP110b may serve as a potential target
220 also caused an increase in synaptic strength, suggesting that spontaneous neurotransmission is able
221 is partly due to gene copy number imbalances, suggesting that subtle changes in gene expression impa
222 um cytokine levels in normal and athymic mice, suggesting that T cells play a negligible role in the
223 ation of supernumerary megaspore mother cells, suggesting that TEX1- and TAS3-mediated restriction of
224 S, and PREP family members, but not with TGIF, suggesting that TGIF may have an independent input int
225 P-2 sigma2 subunit BiFC signal and vice versa, suggesting that the AP-2 alpha-sigma2 hemicomplex inte
226 er native conditions, was markedly disordered, suggesting that the beta-annulus had been disrupted an
227 e-proximal region of the N terminus of chECL1, suggesting that the binding site of ALV-J gp85 on chNH
228 d to harbored few metabolism-associated genes, suggesting that the canalization of metabolism is larg
229 ed compared to that in the Cbl-depleted cells, suggesting that the Cbl-Nectin-1 interaction is likely
230 y with the chirality-associated Marcus theory, suggesting that the energy gaps between SWNT and the L
231 18S-E in Bystin-associated pre-40S particles, suggesting that the enzymatic activity of PARN is nece
232 shift to shorter acyl chain lengths observed, suggesting that the fatty acid chain elongation proces
233 ing with TCA cycle metabolite pro-drug esters, suggesting that the high levels of cellular 2OG may pr
234 nge of maximal effects as well as Hill slopes, suggesting that the isoboles for drug actions on ion c
235 accounted for 19% increases in soil CO2 flux, suggesting that the leaching of dissolved organic carb
236 ding toward the open conformation of vinculin, suggesting that the MAPK1-vinculin interaction is conf
237 of the patients with EGFR-TKI-resistant NSCLC, suggesting that the NGS-based ctDNA assay might be an
238 nation and the vanadium oxide layer thickness, suggesting that the properties of vanadium oxide are s
239 IRAK-1), p38, ERK1/2 MAPKs, and p65 NF-kappaB, suggesting that the R753Q TLR2 polymorphism alters the
240 lization without attenuating the slower phase, suggesting that the S4-S5 linker is important for comm
241 near preferred gamma-secretase cleavage sites, suggesting that the sequence of APP and possibly other
242 noncanonical cyclic dinucleotide 2',3'-cGAMP, suggesting that the STING pathway may be compromised.
243 ndritic arborization of primary motor neurons, suggesting that the structured neuropil could provide
244 cleavage are lower for DeltaTL RNAP variants, suggesting that the TL contributes to the Gre function
245 pe and position of the equatorial reflections, suggesting that the two peptides adopt distinct latera
246 n to demethylation varied between 0.3 and 1.5, suggesting that the two processes are in balance and t
247 was normal and oxidative burst was augmented, suggesting that their innate antimicrobial functions w
248 bition mediated by PV-containing interneurons, suggesting that their sustained silencing could be cau
249 AXL had poor 1-year outcomes after ICH onset, suggesting that therapeutically augmenting efferocytos
250 o those from individuals of European ancestry, suggesting that there might be different genetic facto
251 rent across biomes and plant functional types, suggesting that thermal response of respiratory enzyme
252 rgent from sequences found in other organisms, suggesting that these capacities were not recently acq
253 he antidepressant behavioral effects of SSRIs, suggesting that these cells may represent a novel cell
254 eline and when 9-month declines were compared, suggesting that these compartments are tightly associa
256 nd PML are involved in innate immune response, suggesting that these MRs may correlate with the innat
257 quently developing a hematopoietic malignancy, suggesting that these mutations contribute to disease
258 ection pathway significantly shortened hetDNA, suggesting that these pathways normally collaborate du
259 nd Tyr278 contribute to CdiA-CTYkris activity, suggesting that these residues participate in substrat
260 ments was either insufficient or low-strength, suggesting that these supplements did not reduce risk
261 ntly associated with amyloid deposition in HC, suggesting that these two biomarkers might be used to
262 disequilibrium rapidly decayed around LanFTc1, suggesting that this deletion caused the loss of verna
263 tures of both procyclic and bloodstream forms, suggesting that this intermediate-type metabolism is d
264 n the protection of the adjacent 26-32 region, suggesting that this region may play a regulatory role
265 n events involving the S gene were identified, suggesting that this region may represent a recombinat
266 results were similar to system-scale results, suggesting that this up-scaling method could be useful
267 d Tomt is enriched in the Golgi of hair cells, suggesting that Tomt might regulate the trafficking of
268 equivalent to 11% of net community production, suggesting that under bloom conditions this diazotroph
269 exosomes from WT, but not miR-155(-/-), cells, suggesting that uptake of miR-155-containing exosomes
270 yntenic to many PULs from other Bacteroidetes, suggesting that utilization of yeast and fungal cell w
271 ined the pathogenic E. coli in the subsurface, suggesting that utilizing sand mixed with biochar can
272 nce of HCV on multiple cell surface receptors, suggesting that vaccine induction of multiple NAbs wit
273 VEGF antagonism, a common wet ARMD treatment, suggesting that VEGF inhibition could reduce cellular
274 expression reduced vimentin promoter activity, suggesting that vimentin is an indirect target of miR-
275 s have reduced replication of infectious EBOV, suggesting that VP35 hijacks TRIM6 to promote EBOV rep
276 rand displacement on a nontelomeric substrate, suggesting that WRN recruitment and cooperative intera
277 oduct lactate or antioxidant N-acetylcysteine, suggesting that Y10 phosphorylation-mediated LDHA acti
278 ressed across caste pathways in B. terrestris, suggesting that, in eusocial evolution, the caste-asso
279 mation than those formed along the on-pathway, suggesting the generation of distinct conformeric stra
280 n the 3D structures of bound partner proteins, suggesting the highly conserved nature of 14-3-3 affec
281 to control in a diet-induced obese dog model, suggesting the importance of systemic inhibition of DG
282 presence of detectable inflammatory responses, suggesting the involvement of complex viral mechanisms
283 as differentially sensitive to BFA treatments, suggesting the involvement of different protein kinase
284 ith more unbalanced tumour phylogenetic trees, suggesting the need of denser sampling of tumours at r
285 ain litter decomposition under dry conditions, suggesting the operation of an additional mechanism.
286 associated with reduced adiposity in children, suggesting the possibility to program adipose developm
287 pected from conventional electrostatic gating, suggesting the possible role of a current-gain inducin
288 was significantly increased in severe asthma, suggesting the presence of an altered neutrophil pheno
289 al Abeta42 day/night patterns in older adults, suggesting the previously reported effects of age and
290 ses were retained in TFR patients off-therapy, suggesting the restored immune control observed in MMR
291 e homeostasis in unmanipulated NK1R(-/-) mice, suggesting the role of SP-NK1R signaling in ocular sur
292 ate distinct groups of NF-kappaB target genes, suggesting the unique and irreplaceable function of ea
294 T-cell counts, and immune activation markers, suggesting their pathogenic involvement in AIDS- or no
295 ruited preferentially during context exposure, suggesting their role in encoding context representati
296 connexin 43 and connexin 40 expression levels, suggesting their role in the development of the ventri
297 l into either the high or low gene flux modes, suggesting there are genetic as well as ecological dri
298 tion of brain targets of Galphat-S-ir neurons, suggesting they might mediate non-visual modulation by
300 As and chromatin immunoprecipitation analysis, suggesting transcriptional regulation of EBF1 by AHR.
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