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1 ry symptoms with eosinophilia are most common, though 1 case did involve the central nervous system w
2 r1 KO mice in overall whisker-evoked activity, though 45% fewer neurons in young Fmr1 KO mice respond
3  even at a low multiplicity of infection (MOI), though a reduction in titer was observed.
4 h early (90 days) mortality and graft failure, though a likely but undefined reporting bias for more
5  protein whose exact function remains unclear, though a role of this protein in redox and iron sensin
6  in tumor mutational burden post-chemotherapy, though a significant proportion of subclonal mutations
7                                       Finally, though ABX repeatedly demonstrated an ability to preve
8 ited for implementation in a clinical setting, though additional work is needed to identify why quest
9  vascular regeneration in bioengineered lungs, though additional work is needed to optimize the growt
10 l patterns of gene flow appeared more complex, though again southwest Britain appeared to be an impor
11 ta are incompatible with this geometric bound, though age uncertainties suggest these data could have
12 -153, which was inversely associated with WHZ, though all estimates were imprecisely estimated.
13 rofile compared with extracranial stimulation, though all forms of stimulation are safe.
14  duration, both groups read at similar speeds, though AMD patients demonstrated substantially lower c
15 grees C, significantly affected AOH stability, though AME seemed to not be affected by these thermal
16 , produced for in vitro and in vivo targeting, though an important feature of such a system, has prov
17 relevance of any stimulus needs to be learned, though, and little is known how visual sensory process
18 e present throughout the naive mouse meninges, though are concentrated around the dural sinuses, and
19         Investigations about these conditions, though, are made difficult by the limited range of too
20 ed States, and leads to substantial morbidity, though associated mortality is rare.
21                Open-label ustekinumab therapy, though associated with a modest decrease in ALP after
22 e results indicate that CTD dephosphorylation, though associated with NC maturation in both HBV and D
23 at exceed those in HIV-uninfected populations, though associations are unclear.
24 ally improved specificity over CRP >/=40 mg/L, though at a loss to sensitivity.
25  19 samples, three were positive to safflower, though at levels below the limit of detection, suggest
26 curs ubiquitously and is initially reversible, though becoming more irreversible within minutes after
27                                    There have, though, been contrasting reports regarding the maximal
28 her system was >95% sensitive from the rectum, though both were >99.5% specific.
29 application of advanced carbon-rich materials, though bottom-up synthesis and structure-property corr
30                                Identification, though, can be time-intensive and requires expertly tr
31                    Mutations in the gyr genes, though, can cause variable levels of in vitro FQ resis
32  TKI therapy, another ALK TKI is administered, though collateral sensitivity is not considered.
33   Permutation-based methods are more powerful, though computationally far more intensive.
34                         Bonferroni correction, though computationally trivial, is overly conservative
35                    Risk of HCC after HCV cure, though considerably reduced, remains relatively high a
36 cute serology was nonreactive in all patients, though convalescent serology was reactive in 6 of 8 (7
37 populations in response to a chronic stimulus, though critical for disease outcome, have not been def
38            The simulation based on this model, though currently limited in scope in terms of the biol
39 icity, lower myocardial relaxation velocity E', though demonstrated greater global longitudinal strai
40 mony to the inclusion of nucleotide data that, though derived from actual sequence reads, has been id
41 ts with acutely decompensated liver cirrhosis, though determining CysC at day 3 did not provide any b
42 with EC membranes followed by internalization, though DF did not reach the cell nucleus even after 24
43        Vector carrying shRNA against TGF-beta, though did not inhibit HBV replication alone, enhanced
44 s compared to control group eyes (12/31, 38.7%), though differences were marginally significant (P =
45                  However, some exploited taxa, though economically important, comprise only a small f
46                               Adding biocides, though effective in reducing microbial growth, leads t
47 y worm infection had a poor response to IL-33, though elevated serum IL-33 was observed.
48 horts showed gliosis and degenerative changes, though ERG responses were minimally affected.
49 es also cycle in animals assessed in the wild, though expression is less rhythmic at depth (50-140 m)
50 s, Drosophila Ime4-null mutants remain viable, though flightless, and show a sex bias towards malenes
51 orrelated with derepression in the pkl mutant, though for the majority, decreases in DNA methylation
52 ream, are consistent with the success of fMRI, though functional smoothness breaks down in the later
53 ocess distinguishes these two closely related, though functionally distinct, families.
54 en isolated in many areas but the time delays, though fundamental, generally remain out of reach, par
55 with a terminal Fe(IV) horizontal lineO motif, though further modulations of the core structure due t
56 c reuptake inhibitors can also be recommended, though further studies are needed; (2) augmentation, t
57 ases arise through monogenic coding mutations, though further work is required to unravel the complex
58 ds from standard whole-genome sequencing data, though high computational demands (currently ~30-250 C
59 ased body fat among children 4-9 years of age, though high prenatal DEHP exposure may be associated w
60 hs magnitudes longer than competing processes, though hindered by impurities and intrinsic/extrinsic
61     Sphingolipids are often altered in cancer, though how these alterations lead to tumor formation a
62                                          Thus, though human-dominated landscapes can provide sufficie
63                                       In fact, though hybrids can express a transcriptome similar to
64 stant spread including that of lobular cancer, though identification of hepatic metastases was limite
65 ate hemodynamically and suffer high mortality, though identifying these specific patients remains cha
66 Cs, either undifferentiated or differentiated, though IFNgamma receptor expression was comparable.
67 ns in the neural circuit on which leptin acts, though in most cases, the pathogenesis of leptin resis
68 pending on location and ownership perspective, though in New York, these emissions can be reduced wit
69  mussel lineages that exhibited a substantial, though incomplete, genetic differentiation.
70                We show that human performance, though inconsistent with models involving direct (unco
71  whether population density or area increases, though increases in density over 7000 people per squar
72  for such in-breast events persists over time, though increasing age at cancer diagnosis and treatmen
73 ns the mainstay pharmacologic therapy for CRS, though indications for administration vary among cente
74 us methodological advances have also occurred, though inertia has slowed their adoption.
75 d in discussing breastfeeding as a reasonable, though inferior, option.
76                       Octyl-modified SiO2 NPs, though initially more aggregated than uncoated SiO2 NP
77 ions as a basis for universal health coverage, though interventions can address focused problems on a
78               Increasing water use efficiency, though, is unlikely unless there is simultaneous stabi
79  label-free optical detection of biomolecules, though it currently suffers of limited clinical diagno
80 termediate consumer in the tri-trophic system, though it decreases those of both basal species and to
81 copic idealization of a drop to the nanoscale, though it does not geometrically resemble a realistic
82 niasis (VL), is comparatively less well known, though it is an increasingly recognized concern for in
83 sZ directs PG insertion at the division plane, though it is unclear how FtsZ structure and dynamics a
84 and functionally early in disease progression, though it is unclear what causes astrocytes to become
85  adherence, cytotoxicity, or serum resistance, though it profoundly reduced the ability of the mutant
86 to 70% of SHIV-327c in vitro, did not prevent, though it significantly delayed, establishment of infe
87 ZIKV infects neural progenitor cells in vitro, though its effects on other developmentally relevant s
88  lumen continuity in developing renal tubules, though its mechanism of action remains unknown.
89 ibed as a low-permeant neutral CB1 antagonist, though its pharmacology is still unclear.
90 recently been connected with effector T cells, though its role is still not clear.
91 2011], Malays [recruited from August 16, 2004, though July 10, 2006], and Indians [recruited from May
92 cally feasible to synthesize FAU with SAR=2-7, though kinetic factors seemingly impose a more restric
93 d hydrogen-production potentials for x < 0.26, though large variance in literature values for certain
94 r of 2 of emissions reported to USEPA or CARB, though large variance was observed and the reporting d
95 well to initial stretch acceleration or dF/dt, though later transients were only described by dF/dt.
96  lens position than fellow eyes and PACS eyes, though lens thickness did not differ among the groups.
97 capping enzyme mutant increased significantly (though less than that of wild-type virus) in DKO A549
98 immune cell subsets, MOSPD2 was apparent also, though less abundantly, in neutrophils, but not in lym
99  with the semantic variant were also impaired, though less severely.
100                                  Our findings, though limited by small numbers of cases, suggest that
101 e to catalyze the 4e-ORR in alkaline solution, though limited within a narrow potential window.
102                               Genetic studies, though limited, have demonstrated both the uniqueness
103  outcomes has been observed for esophagectomy, though little is known about why or how patients choos
104 available to assess adipocyte differentiation, though little work has been done to standardize protoc
105 s hidden, and the surface plasmon excitations, though localized at the surface, are characterized by
106 tood for the accumulation of most polyphenols, though low-carotenoid cultivars with high accumulation
107 sessed via continuous performance tasks (CPTs), though many place additional cognitive demands with l
108 te based magnetometers pose a viable solution, though many are prone to radiation damage and plagued
109        In spite of this performance potential, though, many users find method development challenging
110                                      Moreover, though mean facet diameter and facet number increased
111 pectations (mean, 100; standard deviation, 15), though measures of executive function, processing spe
112 s thought to require T cell entry into tumors, though mechanisms regulating this process remain uncle
113  including metabolic syndrome (MetS) features, though metabolomic markers have not been investigated.
114                Recellularization was achieved, though methodological advances are required regarding
115 ery high selectivity for uranyl ion detection, though minor interference from Cu(2+), Pb(2+), Hg(2+),
116 nly one set of experimental data is available, though modest results were obtained when dealing with
117 diabetes was also associated with significant, though more modest, excess cardiovascular risks, with
118 oach does lead to a bias that is fairly small, though more research is needed.
119 1999 to 2012, total water use increased by 30% though much of that increase was derived from reuse of
120          All analogs acted as SERT substrates, though N-butyl 4-MA had very weak effects.
121 oral abnormalities and nervous system defects, though neither affected cell types nor impaired signal
122  increased ID (AOR = 2.41; 95% CI: 1.18, 4.91), though no trend was suggested.
123 oxide on a pendant Mn horizontal lineO moiety, though no chemical example of this reactivity at a man
124  sponge was isolated as a monoprotonated salt, though no intramolecular hydrogen bond was observed.
125 P < 0.001) were predictive of hospital bypass, though no significant association between mortality ra
126 e 2, most frequently thrombocytopenia (n = 18), though none required autologous stem cell rescue.
127 s, hypertension and tendency for hyperkalemia, though none had rapid deterioration of renal function.
128  CI, 0.6-1.7) between CLRT-SLT and primary LT, though noninferiority could not be shown.
129          Moreover, representations in several (though not all) of these areas were modulated by featu
130         In contrast, segregation was salutary (though not always significant) for foreign-born Hispan
131 ensus variants at codon 9 downregulated HLA-B (though not HLA-A) significantly better than those harb
132 zenesulfonyl hydrazide 2 as a potent in vitro (though not in vivo) inhibitor of indoleamine 2,3-dioxy
133 ative features (AUC = 0.72; 95% CI: 0.50-0.85), though not significantly (P = 0.32).
134 that the optimal interaction of CA with CPSF6, though not absolutely essential for HIV-1 replication
135 lectively known as the bacterial cytoskeleton, though not all of them are cytoskeletal, affect cell s
136 s approximately 14% of the world's population, though not all predisposing causal risk factors are kn
137 c systems, the translation initiation of many, though not all, mRNAs depends on interaction between a
138 nebula, implying a more compact emission site, though not as compact as, e.g., the synchrotron knot.
139 er a chronic (months postexposure) time scale, though not beyond naturally occurring rates of mortali
140 memory for the event featuring a social model, though not for the non-social condition.
141 perienced power-relevant situations regularly, though not frequently.
142 et each is now recognized as having intricate, though not fully elucidated, biological functions at c
143  or tertiary Ras pathway activating mutations, though not highly recurrent in a single gene.
144 round 95% of the links in the disease network, though not identified by genetic overlap, are discover
145  associated with decreased odds of ASD and ID, though not in girls.
146 sions may form independent of surface lesions, though not likely due to microleakage through very sma
147                                 This approach, though not often used by ecologists, allows ecological
148 lori infection at age 6.5 years was inversely, though not significantly, related to prevalence of ato
149 ed during the first 3 months of de-escalation, though not thereafter.
150 regator are also correlated with IB formation, though not with modeled loop stability.
151 ncreased diversity in the gene coding regions, though obvious blocks were formed on most of the chrom
152                               That contention, though, occasions questions about the psychological dy
153 ngly dominate vehicular total carbonaceous PM, though older non-DPF-equipped diesels will continue to
154 ercent of all respondents offered RI services, though only 61% of HSCs did so.
155  2007 to 174 in 2016 in each respective group, though only the "potential organ donation" cohort show
156 and mental disorders in the last year of life, though opioid use disorder diagnoses near the time of
157  ORRM4 affects editing in a site-specific way, though orrm4 mutation affects editing of the entire tr
158  decrease the global fish production capacity, though our model suggests that this is of secondary im
159 ould be partially explained by tree diversity, though overall fungal diversity was not affected by tr
160 that the earth-abundant aluminum oxide (Al2O3) though paradigmatically known to be an insulator could
161                                 These effects, though partially interlinked, seem to be independent o
162 ese effects generalize to non-social learning, though participants in the social learning experiment
163 r time and in relation to rising temperatures, though phenological responses vary substantially withi
164                     In some specialized cases, though, plant cells are programmed to detach, and root
165 eptor binding at physiological concentrations, though PlGF is predicted to slightly increase VEGFR2 p
166  avoiding excess uptake of external compounds, though poorly understood at the molecular level.
167  MbFe(IV)O by catechin and green tea extracts, though possible confounding reactions need to be consi
168 ly identifying organs at high risk of discard, though potentially transplantable organs are still bei
169 re efficient than averaging of gaze direction, though presenting only the eye region of faces at a la
170                              Pharmacogenetics, though presently confined to the assessment of thiopur
171 CCB performance were detected in either group, though pro-attentional effects of amphetamine in patie
172 s' ability to initiate blebs and thus migrate, though pseudopods are still lost.
173               Asexual reproduction in animals, though rare, is the main or exclusive mode of reproduc
174                Isolated orbital aspergillosis, though rare, should be considered in the differential
175  of pollen deposited during individual visits, though rarely correlated at lower taxonomic resolution
176 es imidazolidinylidenes readily form isolable, though reactive diamino enols with aldehydes and enals
177 raged scientific research into bifidobacteria, though recalcitrance to genetic manipulation and scarc
178 were initially found in tau-negative patients, though recent findings indicate that these mutations a
179 articularly in vivo, remain poorly understood, though recent studies have implicated rho-linked pathw
180 he power of steering for coherence generation, though related to discord, is distinct from existing m
181 d CT also bind to the sarcolemma in the heart, though relatively weak.
182 as lower among infants who underwent ligation, though residual survival bias could not be excluded.
183 ed professional attire in all clinic settings, though respondents in the dermatology surgery clinic w
184 of prior familiarisation or stimulus location, though responses were more variable for cup handling.
185 ed high concentrations of sediment Ni and AVS, though roughly 80% less AVS was observed in surface se
186 ts that topographic accuracy and adaptability, though seemingly incompatible, could be reconciled by
187 duction, and adhesion to nasopharyngeal cells, though serotype 33F survived short-term drying better
188 ell growth and viability, which was partially, though significantly (P<0.05), rescued in the presence
189            The two approaches showed U-shaped, though significantly different, speed-metabolic relati
190  available in pediatric heart transplantation, though similar indications in the maintenance therapy
191 es that can be accommodated by the predefined, though slightly flexible 0D pore.
192 figures or coherent motion caused significant, though smaller shifts in apparent locomotion speed, in
193                                   rAAV.VEGF-A, though stimulating angiogenesis, induced neither peric
194                 Our results show that the IOC, though structurally less organized than an ION, posses
195 y (SCI) leads to profound functional deficits, though substantial numbers of axons often survive.
196 m pathways is essential for such coordination, though such entities remain incompletely known.
197  regulatory 1 cells in health and in AIH/AISC, though suppressive function is lost in patients upon p
198 ss the models and generally worsened with age, though surprisingly there was not a clear correlation
199 r haplotype including DPB1*09:01 was observed, though that haplotype also showed a significant associ
200 .3% [95% confidence interval {CI}, 37.6%-44.3%]), though the AF was substantially lower in the Americ
201 d deviation increase in self-reported alcohol), though the effect size is small.
202 ation when plasma VL was detectable (P = .195), though the magnitude of shedding significantly increa
203 t predictor (hazard ratios, 1.03-1.04; P<0.05), though the number of events was small.
204 ose rhodamine-labeled mannosylated BSA (rMBSA), though the receptor was not involved in the uptake of
205 le in KI/KI brains and reduced in KI/+ brains, though the Abeta42/Abeta40 ratio is slightly increased
206  zebrin positive (Z+) and negative (Z-) cells, though the amplitudes of the phases were larger in Z+
207  Deletion of arnS results in reduced motility, though the archaellum is properly assembled.
208 g age were more likely to have higher torsion, though the association between advanced age and greate
209 rease (95% CI: -111.6, -14.2) in birth weight, though the association was null in the other strata.
210 vements were found 12 months after T-ionto CL, though the average improvement in corneal topography r
211 in Ca(2+) sensitivity of force was attenuated, though the Ca(2+) sensitivity of the force-pCa relatio
212  magnitude faster than the existing pipelines, though the consensus sequence error rate is as high as
213 ed serum complement activity in schizophrenia, though the data are inconclusive.
214 aller (121.60 +/- 10.40%) than the DMSO group, though the difference was not statistically significan
215 mples from Antarctic continental shelf waters, though the difference was not statistically significan
216 made considerable progress in the last decade, though the disassembly processes remain underexplored.
217 ear to be successful in achieving weight loss, though the durability of these interventions is not kn
218 en alcohol exposure and risky decision-making, though the enduring effects of adolescent ethanol expo
219 l wipes thought to contain the inciting agent, though the exact nature of this remains unclear.
220  stroke, infection and traumatic brain injury, though the exact role of the immunoproteasome in neuro
221 ies mostly resembled those of FtsZ2 and FtsZA, though the glaucophyte protein exhibited some hybrid f
222 tly influence the prioritization of chemicals, though the impact of such influences is unclear.
223  seed-based analyses provided similar results, though the latter and their combination were most info
224 anges in ACF were also altered in CRC samples, though the magnitude of change at these sites was less
225 n with conversion of forest land to crop land, though the magnitude of such conversion is uncertain b
226 equired for transcription of piRNA precursors, though the mechanism by which it licenses transcriptio
227 mediated by the mitochondrial disulfide relay, though the mechanism by which the disulfide bond in Ti
228 ncomitant increase in viral protein synthesis, though the mechanism by which the virus achieves this
229 ore the main pulse inhibits startle responses, though the mechanism for this remains unknown.
230 ed with a recognizable developmental syndrome, though the mechanism of action of pathogenic missense
231  in Matrin 3 have recently been linked to ALS, though the mechanism that induces disease in these pat
232 can dramatically impact ecosystem functioning, though the mechanisms are not well understood beyond b
233 tional NPLRD families with the R246Q mutation, though the mechanisms by which LMX1BR246Q causes a ren
234 l sclerosis (ALS) and frontotemporal dementia, though the mechanisms by which such expansions cause n
235 wth by inhibition of canonical Wnt signalling, though the mechanisms through which this occurs remain
236 le kidney cells and mechanosensory hair cells, though the mechanisms underlying cell death are not cl
237 aberrant accumulation of lipid in hepatocytes, though the mechanisms whereby this leads to hepatocyte
238 f the small intestine for fructose is limited, though the molecular mechanisms controlling this proce
239 d by physical properties of the moving object, though the neural mechanisms underlying this process r
240 nversely associated with birth weight z score, though the null value was included in all credible int
241 ity through a structure-function relationship, though the organizational properties of these multicel
242 treatments affected both inflammatory markers, though the patterns were complex and different for eac
243 ic inflammatory response syndrome from sepsis, though the performance in some datasets was low (area
244  other class B GPCRs, displays biased agonism, though the physiologic significance of this is yet to
245 n all three data compared to other approaches, though the power gain is smallest in the smallest samp
246 eline mosquitoes are now ubiquitous in Africa, though the public health impact remains unclear, imped
247 ed to drive the plasma wake in the experiment, though the quasi-linear wake structure could as easily
248 reatment strategy for cryptococcal meningitis, though the rising price may be creating access issues
249 al samples and for discovering novel isoforms, though the techniques to analyze the resulting data ar
250 y proteins have been associated with scission, though the underlying molecular details of how scissio
251 merization, mediated by helical SARAH domains, though the underlying molecular interaction mechanism
252 rized by high susceptibility to EBV infection, though the underlying pathological mechanisms have not
253 I) system binds and cuts DNA using guide RNAs, though the variables that control its on-target and of
254 FDG studies are typically employed in rats [2] though the technology has been applied to birds [3].
255 croscopically separating into distinct phases, though, the two bonding types are tightly interwoven,
256 ession strongly correlates with Th2 pathology; though, the mechanism is as yet elusive.
257 (tDCS) has been used in stroke rehabilitation, though their combinatory effect is unknown.
258 uggested to possess mechanosensory properties, though their mechanism of action is fully unknown.
259  remain the mainstay of therapy in most cases, though their mechanism of action remains poorly unders
260  TBI group reported more fatigue than the HCs, though their performance was comparable.
261 hypoglycaemic responses on systemic injection, though their potency was about 40% of that of natural
262 receives both afferent and associative inputs, though their relative contributions to odor perception
263  resource for subsequent in silico validation, though their use can lead to data integration issues.
264 ling during reinforcement learning (session 2), though there was no main effect of stress on RPE.
265 chorus capsularis are commercially cultivated, though there are more than 100 Corchorus species(2) in
266 improved waitlist and posttransplant outcomes, though there is a high risk of selection bias in the a
267 or EPA and DHA and advanced AMD is discordant, though there was no association with advanced AMD in t
268 c carbon (TOC) or chemical oxygen demand (COD), though these parameters do not provide information on
269  as a pedagogical and community building tool, though these benefits would hinge on large-scale UF pr
270 e who showed stability of or loss of body fat, though these effects were partially driven by reductio
271                                       Overall, though, these data suggest that HEV infection is rare
272 ase mediated through the ryanodine receptor 1, though they do affect myotube size and nuclear content
273  clearance resulting in poor in vivo activity, though they may be very potent compounds in vitro.
274 ot primarily dependent on DICER-LIKE proteins, though they seem to be associated with ARGONAUTE prote
275 n about tipping of oscillations (limit cycles) though this dynamics are the typical response of many
276  percentage point increase, 95% CI -0.07-7.19), though this association was only marginally significa
277 cant overall effect of status on RS (r = 0.19), though this effect was significantly lower than for n
278 mpacted cocoa butter crystallization kinetics, though this depended on surfactant structure and conce
279 ments investigated were degraded about 5-fold, though this fact can be expected to stem from a change
280  toxic threshold in freshwater and some soils, though this is more likely with high-production ENMs s
281 cognitive insight is impaired in compulsivity, though this is supported by scant empirical evidence.
282 evolutionary frozen accidents or optimization, though this optimization may also be for systems-level
283 caspase-1-dependent interleukin-1beta release, though this phenotype could be suppressed by pharmacol
284 with Sb-R in the mechanisms of MIL resistance, though this requires an enhanced understanding of the
285 nt, we show that these results are replicable, though to a lesser extent, when measuring sleep over a
286 -mRNA binding regions in two newly discovered, though uncharacterized, regulatory RNAs.
287 ar model system to study biological processes, though uncovering recessive phenotypes requires inacti
288 an genome and dysbiosis of the gut microbiome, though unifying principles for these findings remain l
289 tes were highly negative for all four species, though variable in magnitude.
290 talization in older adults who were not frail, though VE diminished as frailty increased.
291  expression is restricted to the right atrium, though ventricular hypertrophy is accompanied by incre
292 citation and inhibition in the nervous system, though we have only a limited understanding of the mec
293 between camera-NDVI and leaf nitrogen content, though weaker relationships between camera-NDVI and LA
294     The glycan on GluN2B-N688 shows a similar, though weaker, effect.
295  motor cortex between 60 and 90 Hz, a similar, though weaker, oscillation in subthalamic nucleus, and
296 Thicker soil organic layers also reduced ALTs, though were less influential than moss thickness.
297                             Malaria parasites, though widespread among wild chimpanzees and gorillas,
298 he 8-oxoguanine and thymine dimer DNA lesions, though with a 10(3) and 10(2)-fold lower efficiency, r
299 ffraction data to retain the P213 space group, though with a cubic lattice parameter of a = 9.11176(8
300  to successfully classify test samples of C-4, though with a limited degree of certainty.

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