ライフサイエンスコーパス: -binding

1 which was reduced after mutation of the Sp-1-binding site.

2 hemic injury in vivo The minimal syntaxin 1A-binding sequence of Kv2.1 C terminus (C1aB) was first id

3 ing cell nuclear antigen (PCNA) as a nIGF-1R-binding partner.

4 n in an unprecedented mu(2) :eta(2) ,eta(2) -binding mode.

5 neurotransmitter release by virtue of Ca(2+)-binding to their two C2 domains, but their mechanisms of

6 tion initiation factor 4E, phosphorylated 4E-binding protein 1, and p-S6 ribosomal protein.

7 led by the 3' poly(A) tail (PAT) and poly(A)-binding protein (PABP).

8 at regulated expression of cytosolic poly(A)-binding protein 1 (PABPC1) modulates protein synthetic c

9 y induction through interaction with poly(A)-binding proteins.

10 ied the YEATS domain as a novel acetyllysine-binding module; however, the functional importance of YE

11 sion of C/EBPalpha, PPARgamma and fatty acid-binding protein 4 (FABP4).

12 ndroitin sulfate-containing, hyaluronic acid-binding proteoglycan present in the extracellular matrix

13 second-pulsed laser to bleach a nucleic acid-binding dye causing dose-dependent apoptosis of individu

14 r ICAM-1 is negatively regulated by an actin-binding adaptor protein, i.e., CD2AP, to allow a balance

15 ontaining a proline-rich domain and an actin-binding Wiskott-Aldrich syndrome protein homology 2 (WH2

16 mods have alternating tropomyosin- and actin-binding sites (TMBS1, ABS1, TMBS2, ABS2), Lmods lack TMB

17 9-amino-acid protein containing five F-actin-binding sites and two G-actin-binding sites, and interac

18 g five F-actin-binding sites and two G-actin-binding sites, and interacts with wheat (Triticum aestiv

19 beta-III-spectrin, and likely similar actin-binding proteins, interact with actin, and how this mech

20 16 of protein 4.1R encodes a spectrin/actin-binding peptide critical for erythrocyte membrane stabil

21 ia type 5 (SCA5) L253P mutation in the actin-binding domain (ABD) of beta-III-spectrin causes high-af

22 ytoskeleton in IECs via changes in the actin-binding proteins VIL1 and GSN.

23 Talin contains three actin-binding domains (ABDs).

24 istinct, independently regulated, co-agonist-binding site.

25 proportional to FcRn expression and albumin-binding affinity.

26 (18)F-florbetapir (Amyvid) is an amyloid-binding PET ligand with a half-life suitable for clinica

27 residue Val-136, which lines the anesthetic-binding cavity, its flanking residues (132 to 140), and

28 The aminocatalysis and anion-binding catalysis sites of the dual-function rotaxane ca

29 The anion-binding catalysis results from a pair of triazolium grou

30 d Hex nanocarrier exhibited similar antibody-binding behavior, but delivered more antibodies to their

31 resonance, were recloned as IgE and antigen-binding fragments.

32 rsatile scaffolds to display diverse antigen-binding surfaces.

33 nitial prediction of human leukocyte antigen-binding peptides by in silico algorithms, but the predic

34 ific amino acid polymorphisms in the antigen-binding clefts.

35 on of adenylate-uridylate-rich element (ARE)-binding protein BRF1, a target of PI3K-Akt.

36 three of the GW/WG repeats in its Argonaute-binding domain: motif-1, motif-2, and the hook motif.

37 se seeded by the aggregation of specific ASO-binding proteins such as FUS/TLS (FUS) and PSF/SFPQ (PSF

38 B4 (MDR3) is an adenosine triphosphate (ATP)-binding cassette (ABC) transporter expressed at the cana

39 protein complex LptB2FG is unique among ATP-binding cassette transporters because it extracts lipopo

40 ABCG4 is an ATP-binding cassette transmembrane protein which has been sh

41 by targeting the conserved catalytic and ATP-binding (CA) domain.

42 Multidrug resistance (MDR) mediated by ATP-binding cassette (ABC) transport proteins remains a majo

43 on of metabolites is in part mediated by ATP-binding cassette (ABC) transporters.

44 The subfamily C ATP-binding cassette (ABCC) transporters mediate multidrug r

45 nteractions with purified P-gp and other ATP-binding cassette transporters that transport amphipathic

46 ted patients who harbor mutations in the ATP-binding sites of ABCB4.

47 um sensing via antagonism of the autoinducer-binding receptors, LasR and RhlR.

48 First, we identified a light-sensing B12-binding transcriptional regulator and demonstrated that

49 CLCNKB mutations in barttin-binding sites, dimer interface or selectivity filter oft

50 splayed increased expression of S100 calcium-binding A4 (S100A4), a protein linked to cancer cell pro

51 se, myosin light chain, sarcoplasmic calcium-binding protein, and hemocyanin are the most relevant.

52 3p must be in complex with the small calcium-binding protein Cdc31p to be active.

53 The calcium-binding protein S100A4 is expressed at elevated levels i

54 ontaining aromatic amino acids, the caveolin-binding motif.

55 n start sites (TSS), and the number of CCCTC-binding factor (CTCF)-cohesin complexes between the inte

56 ecruiting a complex containing Cla4, a Cdc42-binding effector, Bem1, a scaffold, and Cdc24, a Cdc42 G

57 he complete energetic landscape of the Cdc42-binding site on ACK.

58 of an rcSso7d binding module and a cellulose-binding domain.

59 We identified a centrin-binding site within H. sapiens Prp40 homolog A (HsPrp40A

60 ressing a FRET-biosensor comprising the cGMP-binding sites of PKGIalpha.

61 FMRP is both an RNA- and channel-binding regulator, with critical roles in neural circuit

62 We conclude that chemokine-binding evasin proteins are widely expressed among tick

63 so includes the light-harvesting chlorophyll-binding proteins of photosystems I and II, the early-lig

64 ntify two, to our knowledge, new cholesterol-binding sites on the A2A adenosine receptor, a G-protein

65 unclear whether PFO* and related cholesterol-binding proteins bind uniformly to the plasma membrane o

66 ring a cavity resembling that of the choline-binding protein ChoX, as revealed by crystal and density

67 us, our work identifies a critical chromatin-binding DNA damage response factor, ZMYM3, which modulat

68 and a subset of nucleotides in the cobalamin-binding pocket.

69 a consequence, it is possible that collagen-binding cells may change their phenotypic traits.

70 ical peptide that reconstitutes the collagen-binding domain for integrins GFOGER reverted the assembl

71 Deletion of the distal CTCF-binding site results in loss of Ramp3 expression in non-

72 re repeats can initiate at subtelomeric CTCF-binding sites to generate telomere repeat-encoding RNA (

73 etrograde actin flow with their cytoskeleton-binding beta-subunits tilted by applied force.

74 ared concentrations of 25(OH)D and vitamin D-binding protein (VDBP) in AA and EA women and investigat

75 ng of the temperature dependence of the DBMP-binding energy and emission intensity shows that the DBM

76 DNA-binding experiments show that the Ml proteins studied bi

77 DNA-binding proteins play a very important role in the struc

78 In this paper, we present iDNAProt-ES, a DNA-binding protein prediction method that utilizes both seq

79 seq and 4sU-RNA-seq to identify aberrant DNA-binding events genome wide and ectopic transcriptional c

80 n for epistasis between mutations across DNA-binding sites.

81 RARbeta ligand-binding domain (LBD) and DNA-binding domain (DBD) are physically connected to foster

82 omplexa-specific proteins containing AP2 DNA-binding domains (ApiAP2s) was identified in malaria para

83 like factor-1 (KLF1) leads to degenerate DNA-binding specificity in vivo, resulting in ectopic transc

84 the X-ray crystal structure of an EBNA1 DNA-binding domain (DBD) and discovered a novel hexameric ri

85 s the usefulness of PSSM-RT for encoding DNA-binding residues.

86 es or heterozygous males with an ERalpha DNA-binding domain mutation knocked in (WT/KI) to produce WT

87 a gene for a ubiquitously expressed Ets DNA-binding domain-containing transcriptional repressor.

88 nalysis of enriched transcription factor DNA-binding sites in the promoters of differentially express

89 ranscription factor dimerization impacts DNA-binding specificity is poorly understood.

90 ation in the characteristic caliper-like DNA-binding conformation and the second monomer exhibiting d

91 In our proposed mechanism, DNA-binding-domains (DBD) of R insert in major grooves of O

92 latory metal coordination in an open non-DNA-binding conformation.

93 nism by which competitive recruitment of DNA-binding nuclear receptors/transcription factors in trans

94 cAMP responsive element binding protein DNA-binding activity prevented the proliferative effects of

95 and a beta-hairpin within this putative DNA-binding cleft that are essential for catalytic activity.

96 rated that Hop1 is a structure-selective DNA-binding protein exhibiting high affinity for the Hollida

97 lex, incorporating the sequence-specific DNA-binding protein Cep3 together with regulatory subunits C

98 nature with numerous round, hyaline, TAR DNA-binding protein 43 (TDP-43)-positive inclusions.

99 ize the cell-to-cell transmission of TAR DNA-binding protein and alpha-synuclein, involved in amyotro

100 been well studied for over a decade, the DNA-binding activities and the biological functions of these

101 a (RXRalpha), and phosphorylation of the DNA-binding domain (DBD) at Thr-38 in CAR regulates this con

102 The DNA-binding sites of estrogen receptor alpha (ERalpha) show

103 d features of proteins to identify their DNA-binding functionality.

104 d knockin mice with a mutation in the TR DNA-binding domain that abrogates binding to DNA and leads t

105 er-inducing interferon-beta (TRIF) and Z-DNA-binding protein 1 (ZBP1)/DNA-dependent activator of IFN-

106 /2 [LIM domain only 1 or 2]:LDB1 [LIM domain-binding protein 1]) and dynamic recruitment of conserved

107 se tissues and a genome-wide analysis of Dsx-binding sites.

108 three 3'CITEs enhance translation: the eIF4E-binding Panicum mosaic virus-like translational enhancer

109 WT mice, including sterol regulatory element-binding protein 1c target gene fatty-acid synthase (3.0-

110 the phosphorylation of cAMP response element-binding (CREB) protein on the IL-10 promoter.

111 show that the carbohydrate response element-binding protein (ChREBP) coordinates an adaptive respons

112 is a direct target of cAMP response element-binding protein (CREB) that is activated by beta-adrener

113 e --> cAMP --> PKA --> cAMP response element-binding protein pathway mediating cell survival and the

114 by its human homolog Ras-responsive element-binding protein 1 (RREB-1).

115 ifically, in the presence of ethylene, ENAP1-binding regions are more accessible upon the interaction

116 tubule network and the microtubule minus end-binding protein, Patronin.

117 n vivo Furthermore, live-cell imaging of end-binding protein 3 tagged with EGFP (EB3-GFP) in primary

118 s in the molecular bridge, so-called exciton-binding.

119 Finally, analysis of transcription factor-binding site motifs of differentially dysregulated genes

120 s other than changes in transcription factor-binding sites that drive patterning.

121 nto a hexameric coiled-coil bundle and an Fc-binding Protein A fragment, we generated the Hex nanocar

122 This caused a disruption of Fc-binding and phagocytosis.

123 .3-fold increase after 1 h for the high FcRn-binding albumin variant compared with wild-type albumin.

124 n in cell culture media corresponded to FcRn-binding affinity, with a approximately 3.3-fold increase

125 ged in a radial manner from a minimal flavin-binding scaffold.

126 onstrate that amino acid substitutions in Fn-binding repeat-9 can significantly affect bond strength

127 Transcriptome and genome-wide GABP-binding site analyses identify GABP direct targets encod

128 domain that are located distal to the Galpha-binding interface.

129 2 coactivated the transcription factors GATA-binding protein 4 (GATA-4) and hypoxia-inducible factor

130 Specifically, a Gbetagamma-binding/activating peptide, mSIRK, increases DA efflux t

131 with other amino acid residues in the GERAMT-binding site for proper chaperone-dependent regulation o

132 eceptor (NMDAR) is controlled by a glutamate-binding site and a distinct, independently regulated, co

133 Since the locked glutamate-binding clefts primarily contributes to receptor efficac

134 rs investigations into the biology of glycan-binding proteins, which in turn complicates the biomedic

135 Probing the array with several glycan-binding proteins uncovered that not only terminal glycoe

136 UV-induced covalent binding to GSTs and GSH-binding enzymes.

137 Septins are filament-forming GTP-binding proteins involved in many essential cellular eve

138 ), a negative regulator of the Ras small GTP-binding protein.

139 post-translational prenylation of small GTP-binding proteins such as Rho and Rac, and their downstre

140 site shows structural similarity to the GTP-binding site of MoaA, suggesting that the viperin substr

141 nitrite reductase gene (aniA), the factor H-binding protein gene (fHbp), and the capsule biosyntheti

142 ethylation, is accommodated by BAF45C's H3K4-binding site.

143 aled that specific modifications in the heme-binding (R374W and R448C) or substrate-binding (W116C) s

144 e than one modification, cluster in the heme-binding site, supporting a hierarchy of vulnerable amino

145 get protease kallikrein 7 (KLK7) are heparin-binding proteins, and inhibition of KLK7 by vaspin is ac

146 s study, we identified and characterized IgE-binding proteins from the mosquito species Aedes aegypti

147 Some patient sera revealed IgE-binding proteins matching LTP and/or profilin.

148 hermore, we report that calcium and integrin-binding protein 2 binds to the components of the hair ce

149 sitive competition ELISA to measure integrin-binding of RGD-peptides in high-throughput without using

150 ic homeostasis suggest that the RGD integrin-binding domain of IGFBP-1 may be a promising candidate f

151 nctions of the F2 subdomain and the integrin-binding properties of its F3 subdomain.

152 The integrin-binding sites on iC3b remain incompletely characterized.

153 he length of the linker between the two iron-binding catecholamide units was increased from four carb

154 The Patescibacteria LexA-binding motif has unusual direct-repeat structure, and c

155 uctural studies of the beta1AR define ligand-binding sites in the transmembrane helices and effector

156 ucts lacking the entire extracellular ligand-binding domain of the receptor while retaining the trans

157 display near-identical extracellular ligand-binding regions but have intracellular sequences with op

158 AXS) experiments using isolated GluA2 ligand-binding domain (GluA2-LBD) are consistent with binding o

159 pe-specific residues in the PPARdelta ligand-binding domain (LBD).

160 he crystal structure of the PPARgamma ligand-binding domain (LBD) in complex with VSP-51, which revea

161 The RARbeta ligand-binding domain (LBD) and DNA-binding domain (DBD) are ph

162 We insert GFP into the rigid, ligand-binding head of the integrin, model with Rosetta the ori

163 The ligand-binding betaI and alphaI domains of integrin are the bes

164 positive allosteric modulators of the ligand-binding domain of (S)-2-amino-3-(3-hydroxy-5-methylisoxa

165 d a conserved aromatic residue in the ligand-binding pocket.

166 The linker-binding site on the SBD is a potential target for small

167 The C-Mad2-binding protein p31(comet) and the ATPase TRIP13 promote

168 action of the TRIP13 AAA-ATPase and the Mad2-binding protein p31(comet) Now we have isolated from ext

169 d effects of full-length PTEN but a membrane-binding defective mutant of the C2 domain abrogated thes

170 n may affect the positioning of the membrane-binding functions of the F2 subdomain and the integrin-b

171 ilization requires the conserved microtubule-binding Ska complex, which enriches at attachment sites

172 bits the NLS and the neighboring microtubule-binding domain, and RhoA-GTP binding may relieve this in

173 nt HSP mutations, independent of microtubule-binding or severing activity.

174 that She1 directly contacts the microtubule-binding domain of dynein, and that their interaction is

175 motor domain and induces a tight microtubule-binding state in dynein.

176 o identify canonical and non-canonical miRNA-binding sites from peaks identified by Ago2 Cross-Linked

177 including salicylates and diclofenac, as MR1-binding ligands.

178 through a small peptide motif within its MT-binding domain.

179 MYBPC3, encoding cMyBP-C (cardiac myosin-binding protein C), is the most frequently mutated HCM g

180 and in cells expressing low levels of myosin-binding protein C.

181 The internal NHERF-binding region contains both putative Class I (-(592)SAV

182 We report here a few Zika NS1-binding ssDNA aptamers selected using the conventional S

183 Nucleotide-binding oligomerization domain (Nod)-containing proteins

184 containing 1 (NLRP1), NLRP3, and nucleotide-binding oligomerization domain (NOD)-like receptor C4 (N

185 e demonstrate that both TNF-R and nucleotide-binding oligomerization domain stimulation promote ATG16

186 that TRIP8b binds the HCN cyclic nucleotide-binding domain through a 37-residue domain and the HCN C

187 able docking and undocking of its nucleotide-binding domain (NBD) and substrate-binding domain (SBD).

188 's disease susceptibility protein nucleotide-binding oligomerization domain-containing 2 (NOD2); howe

189 The inflammasome proteins nucleotide-binding oligomerization domain, leucine rich repeat and

190 hus, the NTRs affect the specific nucleotide-binding properties of MYO1C isoforms, adding to their ki

191 s, recent evidence indicates that nucleotide-binding oligomerization domains (NODs) can also recogniz

192 el predicted that a region in the nucleotide-binding domain (NBD) of DnaK interacted with a region in

193 the nucleotide-binding domain and substrate-binding domain) in response

194 mJHBP is a member of the odorant-binding protein (OBP) family, and orthologs are present

195 on to dentilisin, most notably, oligopeptide-binding proteins (OBPs) and the beta-barrel of BamA.

196 pair that possesses a poly(ADP-ribose) (PAR)-binding macro domain.

197 que as well as conserved elements in the PAR-binding pocket that can serve as hotspots for the develo

198 chromatin condensation 1 (RCC1) acidic patch-binding protein.

199 ch in a manner similar to other acidic patch-binding proteins such as herpesvirus latency-associated

200 (-(592)SAV-) and Class II (-(595)CLDM-) PDZ-binding motifs (PBMs).

201 induces transcriptional coactivator with PDZ-binding motif (TAZ) expression, which is required for os

202 The family of bacterial Penicillin-binding-protein And Serine/Threonine kinase-Associated (

203 ed that HLA-C*06:02 possesses a deep peptide-binding groove comprising two electronegative B- and E-p

204 t located at position 71, within the peptide-binding groove of HLA-DRB1 (P = 2 x 10(-4) ).

205 RAP is mediated by its phosphoinositide (PI)-binding motif (PBM).

206 PNA-binding proteins may also participate in the patterning

207 n STN1 engenders a selective defect in POLA2-binding and PP stimulation, indicating that these activi

208 sPs and PtdInsPs interact with the polyanion-binding site located on an inner chamber wall of the enz

209 nding and increased CTCF binding in promoter-binding assays, and risk allele carriage diminished tran

210 ly encoded probes consisting of the PtdIns4P-binding domain of the bacterial effector SidM.

211 und -260 and -230 mV, respectively, in the Q-binding site, respectively, suggesting that release of t

212 Raf binding to Rap1 independently of its Ras-binding domain.

213 ly ER-positive metastases that lack receptor-binding functionality.

214 composed of the fusogen gB and the receptor-binding complex gH/gL.

215 ed on the apex of the molecule; the receptor-binding mode might be different from that of retroviruse

216 ted in multiple key residues in the receptor-binding motif (RBM) of RBD and demonstrated their strong

217 Analysis of the receptor-binding properties of the H7 protein of a human isolate

218 Nonetheless, the evolution of the receptor-binding site and the stem region on HA is severely const

219 nd structural plasticity within the receptor-binding site.

220 We also identify the Rere-binding histone methyltransferase Ehmt2/G9a, as a RA coa

221 Plasmodium falciparum reticulocyte-binding protein homologue 2b (PfRh2b) is an invasion lig

222 rkers of dedifferentiation, cellular retinol-binding protein 1, and matrix metalloproteinase 2, compa

223 Similarly, serum levels of retinol-binding protein 4 and retinoids were significantly lower

224 ke translational enhancer (PTE) and ribosome-binding 3' T-shaped structure (TSS) have been found in v

225 uses of different genera, while the ribosome-binding kl-TSS that provides a long-distance interaction

226 n synapses by perturbing the function of RIM-binding proteins (RBPs) as central active-zone scaffoldi

227 RNA-binding proteins of the Musashi (Msi) have been implicat

228 ed to HeLa cells, RBDmap uncovered 1,174 RNA-binding sites in 529 proteins, many of which were previo

229 PrgU has an RNA-binding fold, and prgB-prgU gene pairs are widely distri

230 The Human antigen R protein (HuR) is an RNA-binding protein that recognizes U/AU-rich elements in di

231 nslation machinery and interacts with an RNA-binding protein, FMRP, to promote synapse formation; and

232 al helicase cassettes, while 12 binds an RNA-binding site inside the N-terminal cassette.

233 crystal structures of the Seb1 CTD- and RNA-binding modules.

234 ple neurite-targeted non-coding RNAs and RNA-binding proteins with potential regulatory roles.

235 effector proteins that are recruited by RNA-binding proteins that bind to 3'-UTR cis-elements.

236 This removal is controlled in part by RNA-binding proteins that regulate alternative splicing deci

237 Neuronal protein 3.1 (P311), a conserved RNA-binding protein, represents the first documented protein

238 2 h of hypoxic exposure might deactivate RNA-binding protein BRF1, hence resulting in the selective d

239 r topoisomerases, contains a distinctive RNA-binding domain; and deletion of this domain diminishes t

240 MR1, a conserved, ubiquitously expressed RNA-binding protein.

241 Characterizing the binding behaviors of RNA-binding proteins (RBPs) is important for understanding t

242 diverse stresses trigger coalescence of RNA-binding proteins into stress granules.

243 Liquid-liquid phase separation (LLPS) of RNA-binding proteins plays an important role in the formatio

244 ) is a member of the fragile X family of RNA-binding proteins, which includes FMRP and FXR2P.

245 omain of eIF4G plus an adjacent probable RNA-binding domain mediate translation initiation.

246 d RNA via oligo(dT), it will not provide RNA-binding information on proteins interacting exclusively

247 tion, which requires the Pumilio-related RNA-binding protein Puf118.

248 Large-scale RNA-binding pockets on protein surfaces are grouped by measu

249 have enriched binding motifs for several RNA-binding proteins, which implies extensive translational

250 tion of the RNA-silencing factor HIV TAR-RNA-binding protein (TRBP) promotes binding and stabilizatio

251 try, we further uncovered binding of the RNA-binding protein HuR to the -44 region, where it acts as

252 We found that expression of the RNA-binding protein Mex3a labels a slowly cycling subpopulat

253 The identity of the RNA-binding proteins (RBPs) that govern cancer stem cells re

254 , we identify that PrimPol possesses two RPA-binding motifs and ascertained the key residues required

255 ine insertion sequence (SECIS) and the SECIS-binding protein Secisbp2.

256 gulation of recombinant recognition sequence-binding protein at the Jkappa site (RBP-J) protein, a po

257 s designed based on the sonic hedgehog (Shh)-binding loop of hedgehog-interacting protein (HHIP) and

258 ulted from substitution T401A in the 2nd SIA-binding site, indicating that substrate binding via this

259 ll-specific deletion of recombination signal-binding protein for immunoglobulin Jkappa region (RBPJka

260 re recruited to the cellulosome via a single-binding mode mechanism with an adaptor scaffoldin.

261 s, which binds choline in a unique dual-site-binding mode.

262 the primary amino acid sequence in the SOD2-binding site in hsp70.

263 neered with adhesive and morphogenetic solid-binding peptides is a promising route for synthesizing h

264 me-wide double-strand breaks enriched at Ssb-binding regions and CpG islands, together with the accum

265 PHF11 interacted with the ssDNA-binding protein RPA and was found in a complex with seve

266 Abeta, presumably as both bind at the sterol-binding site on Abcg4.

267 hey exhibited clear differences in structure-binding characteristics.

268 ontains four domains (I-IV), and a substrate-binding domain immediately precedes the catalytic domain

269 ucleotide-binding domain (NBD) and substrate-binding domain (SBD).

270 the nucleotide-binding domain and substrate-binding domain) in response to adenine nucleotides and s

271 ctivity is repressed by a flanking substrate-binding leucine-rich repeat (LRR) domain when substrate

272 heme-binding (R374W and R448C) or substrate-binding (W116C) site of 11beta-hydroxylase, or alteratio

273 hich block substrate access to the substrate-binding groove.

274 insertion of reporter molecules and surface-binding agents in specific locations, which have been re

275 poly(carboxylbetaine) (pCB) and four surface-binding l-3,4-dihydroxyphenylalanine (DOPA) groups, pCB-

276 o involve endocytosis and an initial surface-binding event.

277 ealed that ciA-C2 partially occupies the SV2-binding site on HCA1, causing direct interference of HCA

278 of the interaction between ICP34.5 and TANK-binding kinase 1 (TBK1), an activator of IFN responses.

279 e describe a platform for identifying target-binding cystine-dense peptides using mammalian surface d

280 Although the TATA-binding protein (TBP) subunit of TFIID is necessary and

281 TBK1 under certain conditions through a TBK1-binding domain (TBD), there was no direct impact of the

282 , a portion of the previously described TBK1-binding domain of the gamma34.5 gene (D.

283 ce, we show that TERF1 evolved as a telomere-binding protein in the common stem lineage of marsupial

284 al interactions between Blm and two telomere-binding proteins, which may thus recruit or regulate Blm

285 s contain multiple transcription factor (TF)-binding sites and integrate the effects of each TF to co

286 represent the first analysis of OCRs and TF-binding sites in distinct populations of postmortem huma

287 conjunction with its N-terminal thioredoxin-binding domain, along with a central regulatory region t

288 t Dirac systems by means of continuum, tight-binding and ab-initio calculations.

289 omain of Sec72, even though it lacks the TPR-binding C-terminal residues of Ssa1.

290 ChRs having a mutation(s) at the transmitter-binding sites.

291 TOGs have distinct architectures and tubulin-binding properties that underlie each family's ability t

292 was induced in wild-type (WT) and ubiquitin-binding deficient ABIN1[D485N] mice, and renal pathophys

293 lated regions (UTRs) of MICA, MICB, and UL16-binding protein 2 were shown to be regulated by RBPs and

294 both VEGFR2 and NRP1, including the VEGF164-binding site of NRP1 and the NRP1 cytoplasmic domain (NC

295 a flexible loop near the high-affinity zinc-binding site.

296 a three-helix bundle in the middle and zinc-binding modules on each side.

297 peptoid-based cap groups and different zinc-binding groups.

298 These differences include a novel zinc-binding site and regions unique to the mammalian IP5 2-K

299 at the enzyme represents a new class of zinc-binding flavin-dependent halogenases and provides new in

300 t has similarities to the cysteine-rich zinc-binding domain of DnaJ chaperones.