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1 has been linked to mutations in the Ca(2)(+)-conducting TRP family member PKD2, the suppression of wh
2 cyclic GMP and a cyclic GMP-activated Ca(2+)-conducting channel in the Pep immune signaling pathway.
5 iporter (MCU) is the pore-forming and Ca(2+)-conducting subunit of the uniporter holocomplex, but its
6 ta demonstrate that the NSP4 VPD is a Ca(2+)-conducting viroporin and establish the mechanism by whic
7 review recent studies on how the few Ca(2+)-conducting viroporins exploit host signaling pathways, i
9 ium/ammonia transporter proteins are ammonia-conducting channels rather than ammonium ion transporter
10 Mep2 mutants in residues lining the ammonia-conducting channel reveal separation of function alleles
13 Therefore, we can speculate that such anion-conducting pathways are general features of Na+-transpor
14 est that TM6 is a key component of the anion-conducting pore, but previous cysteine-scanning studies
16 I-III loop chimera was confirmed in the Ca2+-conducting alpha1C/alpha1S II-III loop variant using Cd2
19 6 causes opening of both the central calcium-conducting pore and the alternative cation permeation pa
23 for the architecture and action of the cargo-conducting part of the type-III secretion apparatus.
25 e cation channels, these proteins are cation-conducting channelrhodopsins that carry out light-gated
27 lass of channelrhodopsins (originally cation-conducting) converted into chloride-conducting anion cha
28 rritin fusion protein tethered to the cation-conducting transient receptor potential vanilloid 1 (TRP
29 with this system that, in contrast to cation-conducting channelrhodopsins, opening of the channel occ
30 ase, demonstrates how BcsA forms a cellulose-conducting channel, and suggests a model for the couplin
31 y mutation of a gene that encodes a chloride-conducting transmembrane channel called the cystic fibro
32 l features of these next-generation chloride-conducting channelrhodopsins provide both chronic and ac
33 on; however, these first-generation chloride-conducting channels displayed small photocurrents and we
38 parison of natural ACRs and engineered Cl(-)-conducting mutants of cation channelrhodopsins (CCRs) sh
39 ding ClC-0, ClC-1 and ClC-2) function as Cl--conducting ion channels, whereas others act as Cl-/H+ant
40 , we evaluate how saturation of CR's current-conducting state influences the spatial resolution of fo
41 he energy of ligand binding leads to current-conducting receptors is poorly understood and may vary a
42 al oxides are no exception - protonic-defect-conducting oxides find use in solid oxide fuel cells (SO
43 ane segments of FtsK/SpoIIIE form linked DNA-conducting channels across the two lipid bilayers of the
47 s a hybrid structure composed of an electron-conducting porous framework coated with redox-switchable
49 ric properties of a highperformance electron-conducting polymer, (P(NDIOD-T2), extrinsically doped wi
51 pore size enables the inclusion of electron-conducting species such as [6,6]-phenyl C61 butyric acid
52 cally connects the BOD label to the electron-conducting redox polymer, which is in electrical contact
53 ween the conductive polymer and the electron-conducting substrate (EC) has significant influence on t
54 ion-selective membranes (ISMs) with electron-conducting substrates to construct solid-contact ion-sel
55 l method for fabrication of enzyme entrapped-conducting polymer nanofibers that offer higher sensitiv
56 ally bursting" membrane properties, and fast-conducting descending axons that terminate in multiple s
57 like other nociceptors, these HTMRs are fast-conducting Adelta-fibers with highly specialized circumf
59 expensive unmyelinated axons to large, fast-conducting, and energetically inexpensive myelinated axo
60 fibers, while P2ry1 neurons are largely fast-conducting A fibers that contact pulmonary endocrine cel
64 We predict that patients with viable fast-conducting endocardial tissue or distal Purkinje network
65 at the receptive fields of neurons with fast-conducting axons contained an excitatory center and a su
66 al tract-projecting neurons (PTNs) with fast-conducting axons tended to fire at peak rates in the mid
69 in transmembrane segments and around the gas-conducting lumen recently identified in Escherichia coli
71 three signature amino acids of the glycerol-conducting subfamily into the Escherichia coli water cha
74 light exposure, ChR2 transitions from a high-conducting open state (O1) to a low-conducting open stat
75 ed 1,2-disilaacenaphthenes readily form high-conducting junctions in which the two sulfide anchors bi
76 rtion of GluA2 is coupled to removal of high-conducting Ca(2+)-permeable AMPA receptors from synapses
79 these polymers as light-harvesting and hole-conducting materials are investigated in conjunction wit
80 nduced charge generation capability and hole-conducting property of the novel porphyrin-based PMO fil
82 ed a proton-, oxygen-ion-, and electron-hole-conducting PCFC-compatible cathode material, BaCo(0.4)Fe
85 e sodium (Nav) channel is composed of an ion-conducting alpha subunit and associated beta subunits.
86 e FhuA and Cir plugs, thereby opening an ion-conducting pathway through these channels, and that this
87 angement that leads to the opening of an ion-conducting pore in the transmembrane domain and, in the
88 g of four voltage sensors controlling an ion-conducting pore, and a larger tail that forms an intrace
90 constitute native plugged channels in an ion-conducting state in lipid bilayer membranes have so far
93 r voltage-gated ion channels the central ion-conducting pore is surrounded by four voltage sensing do
96 jugated polyelectrolyte (CPE)-containing ion-conducting polyethylene oxide pendant (PF(PEO)CO(2)Na) a
99 he agonist-binding extracellular domain, ion-conducting transmembrane domain, and gating interface th
100 probe microscopy, we show that the fast ion-conducting channels are not exclusively restricted to th
101 ithium bulk mobility, by creating a fast ion-conducting surface phase through controlled off-stoichio
103 ment of a voltage-gated ion channel form ion-conducting pathways through the voltage-sensing domain,
104 ted SecYEG channel opens to form a large ion-conducting channel, which has the conductivity of the pl
105 rst time, to our knowledge, a 3D lithium-ion-conducting ceramic network based on garnet-type Li6.4La3
109 ween the gating of Hv1 and the gating of ion-conducting pores recently discovered in the VSDs of muta
110 eria) in the anodes of SOFCs with oxygen-ion-conducting electrolytes significantly lowers the activat
111 ogical function, as different cells pair ion-conducting alpha-subunits with specific regulatory beta-
112 n, W1531G created a second non-selective ion-conducting pore, bypassing the outer vestibule but proba
113 a compliant, nonflammable, hybrid single ion-conducting electrolyte comprising inorganic sulfide glas
115 2X4.1 receptor directly reveals that the ion-conducting pathway is formed by three transmembrane doma
119 d define residues that contribute to the ion-conducting pore and affect apoptosis, cell adhesion, and
120 the S6 helices of NaV channels line the ion-conducting pore and participate in channel activation, t
121 ges are crucial for the formation of the ion-conducting pore and the selectivity for protons versus c
122 Specific residues in the HD regulate the ion-conducting pore formed by SARS-CoV E in artificial bilay
123 he controlled opening and closing of the ion-conducting pore in pentameric ligand-gated ion channels.
124 ered by Kvbeta subunits, which block the ion-conducting pore to induce a rapid ('N-type') inactivatio
125 conformational change was coupled to the ion-conducting pore, suggesting that parallel to voltage gat
129 ew mutations that increase access to the ion-conducting states are enough to convert an ATP-binding c
130 subunits, CNGA3 and CNGB3; CNGA3 is the ion-conducting subunit, whereas CNGB3 is a modulatory subuni
132 igand-gated ion channels that open their ion-conducting pores in response to the binding of agonist g
134 FGK2 must therefore stay away from these ion-conducting conformations to preserve the membrane barrie
136 eus Ktr system uniquely comprised of two ion-conducting proteins (KtrB and KtrD) and only one regulat
137 development of functional and high-value ion-conducting vitrimers that take inspiration from poly(ion
139 ith a metallic lithium anode to form a Li(+)-conducting passivation layer (solid-electrolyte interpha
140 anion packing and ionic transport in fast Li-conducting materials and expose the desirable structural
141 angement is present in several known fast Li-conducting materials and other fast ion conductors.
142 m a high-conducting open state (O1) to a low-conducting open state (O2) with differing ion selectivit
143 ransition between the closed state and a low-conducting substate, and validates both the use of the i
144 = 5/2) solid-state NMR spectra of the mixed-conducting solid oxide fuel cell (SOFC) cathode material
149 th dust accumulation are more severe for non-conducting surfaces and have been the focus of this work
150 f carbon-nanotube tips with an imprinted non-conducting polymer coating can recognize proteins with s
157 etal substrates consist of a surface plasmon-conducting metal substrate with a thin amorphous carbon
159 um (ER) is mediated by a dynamic polypeptide-conducting channel, the heterotrimeric Sec61 complex.
163 brane with consequent formation of a protein-conducting channel by the heavy chain (HC) that transloc
166 chain, is unfolded and targeted to a protein-conducting channel for retrotranslocation to the cytosol
167 s target secretory polypeptides to a protein-conducting channel formed by a heterotrimeric membrane p
170 usion of secreted proteins through a protein-conducting channel in the cytoplasmic membrane of eubact
171 membrane proteins transit through a protein-conducting channel in the membrane, the Sec translocon,
172 proteins are translocated through a protein-conducting channel that is formed by a conserved, hetero
173 terotrimeric SecY/Sec61 complex is a protein-conducting channel that provides a passage for proteins
174 re targeted by signal sequences to a protein-conducting channel, formed by prokaryotic SecY or eukary
175 f the cytoplasmic ATPase SecA with a protein-conducting channel, formed from the evolutionarily conse
176 ranslationally targets proteins to a protein-conducting channel, the bacterial SecYEG or eukaryotic S
177 ponent, Tim23, is believed to form a protein-conducting channel, the regions of this subunit that fac
182 re translocons--often referred to as protein-conducting channels--for proper insertion into their tar
185 ecY channel, a universally conserved protein-conducting channel, translocates proteins across and int
186 em consists of the membrane-embedded protein-conducting channel SecYEG, the motor ATPase SecA, and th
188 at SecYEG functions as the essential protein-conducting channel through which precursors cross the me
190 leaves the SNAREs; a central helical protein-conducting channel, which chaperones the protease across
194 gate are reminiscent of features of protein-conducting conduits that facilitate polypeptide movement
197 the translocon, assisting the Sec61 protein-conducting channel by regulating signal sequence and tra
199 ilitated diffusion through the Sec61 protein-conducting channel, while oxidized Bip (Kar2) inhibits t
204 ecedented dual mode of action on the protein-conducting channel acting as a cargo-dependent inhibitor
205 y binding both protein cargo and the protein-conducting channel and by undergoing ATP-driven conforma
206 independent protein substrate to the protein-conducting channel and in assembly of the post-transloco
207 e-protein complex is composed of the protein-conducting channel and the tetrameric Sec62/63 complex.
208 tion and lies at the entrance to the protein-conducting channel in the recently determined SecA-SecYE
209 3 in preprotein translocation to the protein-conducting channel of the mitochondrial inner membrane.
210 interaction with SRP receptor to the protein-conducting channel on endoplasmic reticulum membrane in
211 ified by crosslinking as part of the protein-conducting channel revealed an alpha helix in an amphipa
218 gether support the proposal that the protein-conducting conduit is formed primarily, and possibly ent
220 Tha4 is thought to serve as the protein-conducting element, and the topology it adopts during tr
221 forms a functional complex with the protein-conducting SecY channel to translocate polypeptides acro
226 eviously been implicated as part of a proton-conducting channel delivering protons from the periplasm
229 due Y9 (HO-Y9) functions as part of a proton-conducting wire to transfer a proton back to the steroid
231 precursors by the use of an anhydrous proton-conducting membrane, the solid acid CsHSO4, at 165 degre
233 larger than that of state-of-the-art proton-conducting perovskites or oxide ion conductors at this t
234 atural biomolecules have potential as proton-conducting materials, in which the hydrogen-bond network
237 w of the research progresses made for proton-conducting SOECs, summarizing the past work and finding
238 at the C-family contains a homologous proton-conducting channel that delivers pumped protons in the o
239 has been expended to develop improved proton-conducting materials, such as ceramic oxides, solid acid
240 utations likely enhance the intrinsic proton-conducting activity of Ant, which excessively uncouples
241 ess this issue, we have studied novel proton-conducting materials formed via a chemical reaction of l
242 uggest that nanoscale organization of proton-conducting functionalities is a key consideration in obt
243 technologies that rely on the use of proton-conducting polyelectrolyte membranes is the lack of cont
245 g the problems for the development of proton-conducting SOECs, as well as pointing out potential deve
246 ed morphologies that show outstanding proton-conducting properties, directly related to the state and
247 h affords solid materials with potent proton-conducting properties at moderate temperatures, which is
248 H-bonding residues to form potential proton-conducting channels, and Asp51 exhibits conformational f
250 drogen conversion technology requires proton-conducting materials with high conductivity at intermedi
251 influenza B (BM2) forms a tetrameric proton-conducting channel that is important for the virus lifec
253 differences in the structures of the proton-conducting channels, place critical constraints on model
256 t is thought to form or contribute to proton-conducting hemichannels that allow protons to gain acces
257 nel show the mutual impact of the two proton-conducting channels to be protonation state-dependent.
258 side of the membrane, transferred via proton-conducting channels comprised of hydrogen bond chains co
259 roperties, electrolyte membranes with proton-conducting 2D channels and nacre-inspired architecture a
260 em tracheary elements (TEs) form hollow, sap-conducting tubes kept open by thickened ribs of secondar
262 ctrochemical platform using electrospun semi-conducting Manganese (III) Oxide (Mn2O3) nanofibers for
263 ed organic-inorganic hybrid materials), semi-conducting (metal oxides), or conducting (metals, carbon
265 acts (this work), diffusive metallic or semi-conducting films, graphene, carbon nanotubes and even mo
266 GHz, the conductivity of predominantly semi-conducting assemblies grew to 400% its DC value at an in
267 us, and now liquid-phase, precursors to semi-conducting films; furthermore, these species have been s
269 RFs on the distal limb (wrist/paw) and slow-conducting PTNs typically showed peak firing at the tran
270 dy we compare the activity of fast- and slow-conducting pyramidal tract neurons (PTNs) of the motor c
271 on of white matter shifts from compact, slow-conducting, and energetically expensive unmyelinated axo
272 heterogeneities in tissue excitability, slow-conducting channels, and obstacles that are increasingly
274 tion to accurate stepping on the ladder slow-conducting PTNs more profoundly increase the magnitude o
275 ion to accurate stepping on the ladder, slow-conducting PTNs respond in a much more concerted manner
277 oplastic AV node, with specific loss of slow-conducting cells expressing connexin-30.2 (Cx30.2) and a
278 ntricular ischemic scar for evidence of slow-conducting channels that may act as ventricular tachycar
279 lycogen did not benefit the function of slow-conducting, small-diameter unmyelinated axons (C fibers)
280 ep layers with the transverse-oriented, slow-conducting molecular layer, thereby permitting complex t
288 ns and capacitive coupling between two super-conducting phase qubits were used to generate a Bell-typ
289 ial resistance arising from an insulating-to-conducting phase transition driven by Joule heating.
290 M helix tilting results in an expanded water-conducting channel of an outer dimension similar to the
292 ylogenetic niche conservatism (PNC) in water-conducting and nutrient-use related traits was identifie
293 ale patterning of lignin deposition in water-conducting cells is shown here to vary phylogenetically
295 nts, the polysaccharide-based walls of water-conducting cells are strengthened by impregnation with t
296 structural advances in vascular plant water-conducting systems, promoting P transport that enhances
298 bon starvation or deterioration of the water-conducting pathways from soil to leaf trigger tree morta
299 eal spontaneous formation of transient water-conducting (channel-like) states allowing passive water
300 aining entry into the plant system via water-conducting xylem tissue and was translocated to aerial p
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