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1 has been linked to mutations in the Ca(2)(+)-conducting TRP family member PKD2, the suppression of wh
2 cyclic GMP and a cyclic GMP-activated Ca(2+)-conducting channel in the Pep immune signaling pathway.
6 osterically triggers the opening of a Ca(2+)-conducting pore located ~100 angstrom away from the IP(3
7 iporter (MCU) is the pore-forming and Ca(2+)-conducting subunit of the uniporter holocomplex, but its
8 ta demonstrate that the NSP4 VPD is a Ca(2+)-conducting viroporin and establish the mechanism by whic
9 review recent studies on how the few Ca(2+)-conducting viroporins exploit host signaling pathways, i
11 Mep2 mutants in residues lining the ammonia-conducting channel reveal separation of function alleles
13 est that TM6 is a key component of the anion-conducting pore, but previous cysteine-scanning studies
15 6 causes opening of both the central calcium-conducting pore and the alternative cation permeation pa
19 for the architecture and action of the cargo-conducting part of the type-III secretion apparatus.
21 e cation channels, these proteins are cation-conducting channelrhodopsins that carry out light-gated
23 ily of ion channels and is a divalent cation-conducting ion channel fused with a functional kinase.
24 lass of channelrhodopsins (originally cation-conducting) converted into chloride-conducting anion cha
25 rritin fusion protein tethered to the cation-conducting transient receptor potential vanilloid 1 (TRP
26 with this system that, in contrast to cation-conducting channelrhodopsins, opening of the channel occ
27 ase, demonstrates how BcsA forms a cellulose-conducting channel, and suggests a model for the couplin
28 y mutation of a gene that encodes a chloride-conducting transmembrane channel called the cystic fibro
29 l features of these next-generation chloride-conducting channelrhodopsins provide both chronic and ac
30 on; however, these first-generation chloride-conducting channels displayed small photocurrents and we
35 parison of natural ACRs and engineered Cl(-)-conducting mutants of cation channelrhodopsins (CCRs) sh
36 ding ClC-0, ClC-1 and ClC-2) function as Cl--conducting ion channels, whereas others act as Cl-/H+ant
37 , we evaluate how saturation of CR's current-conducting state influences the spatial resolution of fo
38 he energy of ligand binding leads to current-conducting receptors is poorly understood and may vary a
39 al oxides are no exception - protonic-defect-conducting oxides find use in solid oxide fuel cells (SO
42 s a hybrid structure composed of an electron-conducting porous framework coated with redox-switchable
44 ric properties of a highperformance electron-conducting polymer, (P(NDIOD-T2), extrinsically doped wi
45 pore size enables the inclusion of electron-conducting species such as [6,6]-phenyl C61 butyric acid
46 ween the conductive polymer and the electron-conducting substrate (EC) has significant influence on t
47 ion-selective membranes (ISMs) with electron-conducting substrates to construct solid-contact ion-sel
48 l method for fabrication of enzyme entrapped-conducting polymer nanofibers that offer higher sensitiv
49 like other nociceptors, these HTMRs are fast-conducting Adelta-fibers with highly specialized circumf
50 fibers, while P2ry1 neurons are largely fast-conducting A fibers that contact pulmonary endocrine cel
51 ority of these as expressing markers of fast-conducting neurons, with about two-thirds containing noc
52 ble with monosynaptic transmission over fast-conducting pathways, was observed, as well as longer lat
56 We predict that patients with viable fast-conducting endocardial tissue or distal Purkinje network
57 at the receptive fields of neurons with fast-conducting axons contained an excitatory center and a su
58 al tract-projecting neurons (PTNs) with fast-conducting axons tended to fire at peak rates in the mid
62 three signature amino acids of the glycerol-conducting subfamily into the Escherichia coli water cha
67 light exposure, ChR2 transitions from a high-conducting open state (O1) to a low-conducting open stat
68 ed 1,2-disilaacenaphthenes readily form high-conducting junctions in which the two sulfide anchors bi
69 rtion of GluA2 is coupled to removal of high-conducting Ca(2+)-permeable AMPA receptors from synapses
71 these polymers as light-harvesting and hole-conducting materials are investigated in conjunction wit
72 nduced charge generation capability and hole-conducting property of the novel porphyrin-based PMO fil
74 ed a proton-, oxygen-ion-, and electron-hole-conducting PCFC-compatible cathode material, BaCo(0.4)Fe
77 e sodium (Nav) channel is composed of an ion-conducting alpha subunit and associated beta subunits.
78 e FhuA and Cir plugs, thereby opening an ion-conducting pathway through these channels, and that this
79 angement that leads to the opening of an ion-conducting pore in the transmembrane domain and, in the
80 g of four voltage sensors controlling an ion-conducting pore, and a larger tail that forms an intrace
81 constitute native plugged channels in an ion-conducting state in lipid bilayer membranes have so far
83 gonally functional H-bonding domains and ion-conducting domains to create a polymer electrolyte with
85 he development of commercially available ion-conducting polymers (ionomers) that are employed as memb
87 r voltage-gated ion channels the central ion-conducting pore is surrounded by four voltage sensing do
90 jugated polyelectrolyte (CPE)-containing ion-conducting polyethylene oxide pendant (PF(PEO)CO(2)Na) a
92 he agonist-binding extracellular domain, ion-conducting transmembrane domain, and gating interface th
93 probe microscopy, we show that the fast ion-conducting channels are not exclusively restricted to th
94 ithium bulk mobility, by creating a fast ion-conducting surface phase through controlled off-stoichio
96 ment of a voltage-gated ion channel form ion-conducting pathways through the voltage-sensing domain,
97 on from the regulatory module results in ion-conducting pore collapse and subsequent channel desensit
99 ted SecYEG channel opens to form a large ion-conducting channel, which has the conductivity of the pl
100 rst time, to our knowledge, a 3D lithium-ion-conducting ceramic network based on garnet-type Li6.4La3
107 ween the gating of Hv1 and the gating of ion-conducting pores recently discovered in the VSDs of muta
108 s either present in air, human breath or ion-conducting membranes(9), or generated from labile nitrog
109 eria) in the anodes of SOFCs with oxygen-ion-conducting electrolytes significantly lowers the activat
110 n, W1531G created a second non-selective ion-conducting pore, bypassing the outer vestibule but proba
111 a compliant, nonflammable, hybrid single ion-conducting electrolyte comprising inorganic sulfide glas
114 2X4.1 receptor directly reveals that the ion-conducting pathway is formed by three transmembrane doma
118 d define residues that contribute to the ion-conducting pore and affect apoptosis, cell adhesion, and
119 the S6 helices of NaV channels line the ion-conducting pore and participate in channel activation, t
120 ges are crucial for the formation of the ion-conducting pore and the selectivity for protons versus c
121 Specific residues in the HD regulate the ion-conducting pore formed by SARS-CoV E in artificial bilay
122 he controlled opening and closing of the ion-conducting pore in pentameric ligand-gated ion channels.
124 ered by Kvbeta subunits, which block the ion-conducting pore to induce a rapid ('N-type') inactivatio
125 It also reveals a closed gate in the ion-conducting pore, formed by hydrophobic amino acid side c
126 conformational change was coupled to the ion-conducting pore, suggesting that parallel to voltage gat
128 ew mutations that increase access to the ion-conducting states are enough to convert an ATP-binding c
129 subunits, CNGA3 and CNGB3; CNGA3 is the ion-conducting subunit, whereas CNGB3 is a modulatory subuni
130 igand-gated ion channels that open their ion-conducting pores in response to the binding of agonist g
132 FGK2 must therefore stay away from these ion-conducting conformations to preserve the membrane barrie
135 eus Ktr system uniquely comprised of two ion-conducting proteins (KtrB and KtrD) and only one regulat
137 development of functional and high-value ion-conducting vitrimers that take inspiration from poly(ion
139 ws that it is a highly selective, Na(+)/K(+)-conducting channel and, in contrast to known cation chan
140 g, these results show that the vacuolar K(+)-conducting TPC1 and TPK1/TPK3 channels act in concert to
142 ith a metallic lithium anode to form a Li(+)-conducting passivation layer (solid-electrolyte interpha
143 anion packing and ionic transport in fast Li-conducting materials and expose the desirable structural
144 angement is present in several known fast Li-conducting materials and other fast ion conductors.
145 m a high-conducting open state (O1) to a low-conducting open state (O2) with differing ion selectivit
146 = 5/2) solid-state NMR spectra of the mixed-conducting solid oxide fuel cell (SOFC) cathode material
150 )Te(3) n- or p-type micrograins within a non-conducting polymer as a binder) followed by compression
156 th dust accumulation are more severe for non-conducting surfaces and have been the focus of this work
157 f carbon-nanotube tips with an imprinted non-conducting polymer coating can recognize proteins with s
162 example, we use this method to probe the non-conducting configurations of a double quantum dot, allow
166 etal substrates consist of a surface plasmon-conducting metal substrate with a thin amorphous carbon
168 um (ER) is mediated by a dynamic polypeptide-conducting channel, the heterotrimeric Sec61 complex.
171 chain, is unfolded and targeted to a protein-conducting channel for retrotranslocation to the cytosol
172 s target secretory polypeptides to a protein-conducting channel formed by a heterotrimeric membrane p
175 usion of secreted proteins through a protein-conducting channel in the cytoplasmic membrane of eubact
176 membrane proteins transit through a protein-conducting channel in the membrane, the Sec translocon,
177 o mitochondria by the TOM complex, a protein-conducting channel in the mitochondrial outer membrane.
178 re targeted by signal sequences to a protein-conducting channel, formed by prokaryotic SecY or eukary
179 ranslationally targets proteins to a protein-conducting channel, the bacterial SecYEG or eukaryotic S
184 ing components, a molecular motor, a protein-conducting membrane pore, and accessory membrane protein
186 re translocons--often referred to as protein-conducting channels--for proper insertion into their tar
188 ecY channel, a universally conserved protein-conducting channel, translocates proteins across and int
189 em consists of the membrane-embedded protein-conducting channel SecYEG, the motor ATPase SecA, and th
191 at SecYEG functions as the essential protein-conducting channel through which precursors cross the me
193 leaves the SNAREs; a central helical protein-conducting channel, which chaperones the protease across
195 gate are reminiscent of features of protein-conducting conduits that facilitate polypeptide movement
197 the translocon, assisting the Sec61 protein-conducting channel by regulating signal sequence and tra
200 ilitated diffusion through the Sec61 protein-conducting channel, while oxidized Bip (Kar2) inhibits t
204 ross the membrane through the SecYEG protein-conducting channel using the ATPase SecA, which binds to
205 ecedented dual mode of action on the protein-conducting channel acting as a cargo-dependent inhibitor
206 independent protein substrate to the protein-conducting channel and in assembly of the post-transloco
207 e-protein complex is composed of the protein-conducting channel and the tetrameric Sec62/63 complex.
208 tion and lies at the entrance to the protein-conducting channel in the recently determined SecA-SecYE
209 3 in preprotein translocation to the protein-conducting channel of the mitochondrial inner membrane.
210 interaction with SRP receptor to the protein-conducting channel on endoplasmic reticulum membrane in
214 gether support the proposal that the protein-conducting conduit is formed primarily, and possibly ent
216 Tha4 is thought to serve as the protein-conducting element, and the topology it adopts during tr
217 roteins must translocate through the protein-conducting Sec61 channel in the eukaryotic endoplasmic r
218 forms a functional complex with the protein-conducting SecY channel to translocate polypeptides acro
226 precursors by the use of an anhydrous proton-conducting membrane, the solid acid CsHSO4, at 165 degre
228 larger than that of state-of-the-art proton-conducting perovskites or oxide ion conductors at this t
229 atural biomolecules have potential as proton-conducting materials, in which the hydrogen-bond network
232 The present strategy of a crystalline proton-conducting 2D-polymer will lead to the development of ne
235 ductivity inside the infamous gap for proton-conducting materials(3), which extends from ~100 degrees
236 w of the research progresses made for proton-conducting SOECs, summarizing the past work and finding
237 has been expended to develop improved proton-conducting materials, such as ceramic oxides, solid acid
239 utations likely enhance the intrinsic proton-conducting activity of Ant, which excessively uncouples
240 ess this issue, we have studied novel proton-conducting materials formed via a chemical reaction of l
241 uggest that nanoscale organization of proton-conducting functionalities is a key consideration in obt
242 technologies that rely on the use of proton-conducting polyelectrolyte membranes is the lack of cont
244 g the problems for the development of proton-conducting SOECs, as well as pointing out potential deve
246 ed morphologies that show outstanding proton-conducting properties, directly related to the state and
247 h affords solid materials with potent proton-conducting properties at moderate temperatures, which is
248 H-bonding residues to form potential proton-conducting channels, and Asp51 exhibits conformational f
250 drogen conversion technology requires proton-conducting materials with high conductivity at intermedi
251 influenza B (BM2) forms a tetrameric proton-conducting channel that is important for the virus lifec
253 differences in the structures of the proton-conducting channels, place critical constraints on model
254 PCFC researchers is to formulate the proton-conducting electrolyte with conductivity above 0.1 sieme
255 t is thought to form or contribute to proton-conducting hemichannels that allow protons to gain acces
256 nel show the mutual impact of the two proton-conducting channels to be protonation state-dependent.
257 roperties, electrolyte membranes with proton-conducting 2D channels and nacre-inspired architecture a
258 em tracheary elements (TEs) form hollow, sap-conducting tubes kept open by thickened ribs of secondar
260 ike) and nitrogen and phosphorus-doped (semi-conducting) diamond and hydrogen-terminated undoped diam
261 ctrochemical platform using electrospun semi-conducting Manganese (III) Oxide (Mn2O3) nanofibers for
262 ed organic-inorganic hybrid materials), semi-conducting (metal oxides), or conducting (metals, carbon
264 acts (this work), diffusive metallic or semi-conducting films, graphene, carbon nanotubes and even mo
265 GHz, the conductivity of predominantly semi-conducting assemblies grew to 400% its DC value at an in
266 us, and now liquid-phase, precursors to semi-conducting films; furthermore, these species have been s
269 RFs on the distal limb (wrist/paw) and slow-conducting PTNs typically showed peak firing at the tran
270 dy we compare the activity of fast- and slow-conducting pyramidal tract neurons (PTNs) of the motor c
271 heterogeneities in tissue excitability, slow-conducting channels, and obstacles that are increasingly
273 tion to accurate stepping on the ladder slow-conducting PTNs more profoundly increase the magnitude o
274 ion to accurate stepping on the ladder, slow-conducting PTNs respond in a much more concerted manner
276 oplastic AV node, with specific loss of slow-conducting cells expressing connexin-30.2 (Cx30.2) and a
277 ntricular ischemic scar for evidence of slow-conducting channels that may act as ventricular tachycar
278 lycogen did not benefit the function of slow-conducting, small-diameter unmyelinated axons (C fibers)
279 ep layers with the transverse-oriented, slow-conducting molecular layer, thereby permitting complex t
288 ial resistance arising from an insulating-to-conducting phase transition driven by Joule heating.
289 ulted in an efficient H(+)/O(2-)/e(-) triple-conducting electrode BaCo(0.4)Fe(0.4)Zr(0.1)Y(0.1)O(3-de
290 M helix tilting results in an expanded water-conducting channel of an outer dimension similar to the
291 ylogenetic niche conservatism (PNC) in water-conducting and nutrient-use related traits was identifie
293 structural advances in vascular plant water-conducting systems, promoting P transport that enhances
296 bon starvation or deterioration of the water-conducting pathways from soil to leaf trigger tree morta
298 eal spontaneous formation of transient water-conducting (channel-like) states allowing passive water
299 aining entry into the plant system via water-conducting xylem tissue and was translocated to aerial p
300 studied to date, the diameter of xylem water-conducting conduits D widens predictably with distance f