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1 induce pyroptosis, as measured by caspase-1-dependent interleukin-1beta release, though this phenoty
3 rophysiological recordings show that Sema-1a-dependent R axon lamination is required for preventing t
4 ation of an erythroid-specific, protein 4.1R-dependent membrane skeleton is an important feature not
5 ne potential, facilitates downstream Ca(2+) -dependent pathways and becomes concentrated in specific
8 27 suppressed osteoclastogenesis in an Egr-2-dependent manner that up-regulates Id2, the repressor of
9 on inflammation in a CC-chemokine receptor 2-dependent manner, and the nonclassical blood resident mo
12 1-CXCR2 signaling axis identified HIF-2alpha-dependent neutrophil recruitment as an essential mechani
13 e findings suggest a new paradigm where IL-4-dependent up-regulation of Cox-1 expression may play a k
15 us, and this coincides with TCP20 and NLP6&7-dependent up-regulation of nitrate assimilation and sign
16 at they contain a highly conserved sortase A-dependent cell wall-anchored C terminus, whereas the sur
17 gand increased markers of tricarboxylic acid-dependent and -independent energy biogenesis and oxygen
19 ion and inhibition of a broad range of actin-dependent functions, including phagocytosis, granule exo
22 el RT neurons are predisposed to an activity-dependent switch from GABA-mediated inhibition to excita
23 n the synapse, where well-described activity-dependent mechanisms are known to play a key role in lea
26 a crucial role for this pathway in activity-dependent long-term depression (LTD) at hippocampal Scha
31 inally, we describe a novel form of activity-dependent intrinsic plasticity that persistently elimina
32 ess the spatiotemporal changes of actomyosin-dependent force and stiffness along the antero-posterior
34 haviorally tested mice revealed distinct age-dependent patterns of accumulation in multiple oligomeri
35 aphy of a cuticular drusen distribution; age-dependent variations in cuticular drusen phenotypes, inc
37 e changes in follicle populations showed age-dependent decreases in total follicles and percentages o
39 iously that Rab8a recruits PI3Kgamma for Akt-dependent signaling during TLR4 activation to limit the
40 s as well as alcohol expectancies in alcohol-dependent patients and healthy controls and assessed tre
43 romoting AMP-activated protein kinase (AMPK)-dependent trafficking of KATP and Kv2.1 channels to the
45 reversal characteristics captured by angular-dependent first order reversal curve measurements indica
46 EFL mutations eliminated off-target antibody-dependent monocyte phagocytosis of cynomolgus monkey pla
47 ly induced by vaccines, can trigger antibody-dependent cellular effector functions, through engagemen
48 re is growing interest in utilizing antibody-dependent cellular cytotoxicity (ADCC) to eliminate infe
49 sed approach to specifically mislocalize APC-dependent RNAs suggests that localization of the APC-dep
50 t RNAs suggests that localization of the APC-dependent RNA subgroup is functionally important for cel
53 ndependent helicase, and both ATPase and ATP-dependent helicase activities are inhibited by Rev in a
54 erstanding of the proteasome's multistep ATP-dependent mechanism, its biochemical and structural feat
55 ce of glibenclamide, an inhibitor of the ATP-dependent potassium (KATP)-channels, thus suggesting a p
56 gests that the asymmetry of the three ATPase-dependent 120 degrees power strokes imposed by the relat
57 s of auxin-induced SAUR expression and auxin-dependent elongation growth were closely correlated.
61 d as a moonlighting protein, with two biotin-dependent cytosolic metabolic roles and a distinct bioti
62 TAZ promoter in a CC(A/T-rich)6GG (CArG) box-dependent manner and induced TAZ protein expression.
63 This mechanism is distinct from the BRCA2-dependent fork protection pathway, in which stable RAD51
64 n, acting to drive immune escape via a C3/C5-dependent pathway.Significance: This provocative study s
65 ors (BKIs) of Cryptosporidium parvum calcium-dependent protein kinase 1 (CpCDPK1) are leading candida
66 es of auditory nerve firing, or that calcium-dependent processes involved in release are altered with
67 ) H]ryanodine binding and Ca(2+) /calmodulin-dependent protein kinase II (CaMKII) phosphorylation of
68 re, we show that activated Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) strongly interacts
70 In contrast, when the calcium/calmodulin-dependent protein kinase II (CaMKII) was blocked with KN
71 n recruited calcium/calmodulin (Ca(2+)/CaMK)-dependent protein kinase II (CaMKII) to the hippocampal
72 wide association study data on 2080 cannabis-dependent cases and 6435 cannabis-exposed controls of Eu
73 -independent mechanism that involves caspase-dependent T cell apoptosis and upregulation of inhibitor
74 e ability of HMGA1 to stimulate beta-catenin-dependent transcription, suggesting that interactions be
75 acellular protein that enhances beta-catenin-dependent Wnt signaling and has previously been shown to
77 quires both cyclin-dependent kinase 1 (CDK1)-dependent phosphorylation and its autophosphorylation at
78 molecular link between the processes of Cdk1-dependent priming and self-priming of Plk1 substrates.
81 he mother centriole mediates most centrosome-dependent processes, the role of the daughter remains po
84 cted in MKs and platelets, the impact of CK2-dependent signaling on MK/platelet (patho-)physiology ha
89 roposed to be formed using CysS, a cobalamin-dependent radical S-adenosylmethionine (SAM) methyltrans
90 or-specific antibody (DSA) causes complement-dependent endothelial cell injury in kidney transplants,
91 ivo evidence for contributions of complement-dependent membrane perturbations to prothrombotic TF act
93 ionic substituents and shows a concentration-dependent, tunable transition temperature in aqueous sol
95 Notably, 12 was able to cause concentration-dependent inhibition of cell proliferation, yielding an
98 alcified PFP, purified DNA triggered contact-dependent thrombin generation (TG) and amplified TG init
103 In this study, we generated Zwitch, a Cre-dependent invertible gene-trap cassette, enabling the es
108 totic activation of Gwl requires both cyclin-dependent kinase 1 (CDK1)-dependent phosphorylation and
110 is strictly controlled by a number of cyclin-dependent kinases (CDKs) and CDK inhibitors (CKIs), the
111 ibitors of mTOR and inhibitors of the cyclin-dependent kinases CDK4 and CDK6 substantially improve pr
113 -nucleotide polymorphisms, considering depth-dependent behavior of similarity metrics for identical a
114 marker that is reliable, cheap, less device-dependent, and can be easily and repeatedly used on a la
115 e previously showed that the differentiation-dependent cellular transcription factors KLF4 and BLIMP1
116 ion of MutLalpha endonuclease, PCNA- and DNA-dependent activation of MutLalpha ATPase, and MutLalpha
117 TRIF) and Z-DNA-binding protein 1 (ZBP1)/DNA-dependent activator of IFN-regulatory factors (DAI) that
121 decompensation, mortality, and HCC in a dose-dependent manner (P for trend <0.0001, <0.0001, and 0.00
122 asma levels of fitusiran increased in a dose-dependent manner and showed no accumulation with repeate
123 se activities are inhibited by Rev in a dose-dependent manner, although ATP-independent helicase acti
124 amphetamine-induced hyperactivity in a dose-dependent manner, similar to the atypical antipsychotic,
125 y initiation of liver regeneration in a dose-dependent manner, without modifying the peak regenerativ
126 Patients who received inclisiran had dose-dependent reductions in PCSK9 and LDL cholesterol levels
128 oactive component of cannabis, produced dose-dependent conditioned place aversion and a reduction in
129 we observed that 1B6 displayed a rapid dose-dependent clearance (t(1/2) 10-60 h) in contrast to 1F11
130 n A small but statistically significant dose-dependent T1-weighted signal enhancement was observed in
131 verexpression results in a significant, dose-dependent increase in EGFR tyrosine phosphorylation, par
136 hus constitute a common endpoint of both EMT-dependent and EMT-independent cancer dissemination progr
137 stress, associated impairment of endothelium-dependent vasorelaxation, and preserves endothelial Sirt
138 antibodies reduced tau uptake in an epitope-dependent manner: N-terminal (Tau13) and middomain (6C5
140 active targets for the treatment of estrogen-dependent diseases like endometriosis and breast cancer.
143 ocaine CPP extinction and lack of extinction-dependent changes in hippocampal PSD CaMKII expression a
145 ss if FANCI is also involved in these FANCD2-dependent mechanisms, we generated isogenic FANCI-, FANC
146 superlattice period-, temperature- and field-dependent evolution of these structures, we observe seve
148 epresents a new class of zinc-binding flavin-dependent halogenases and provides new insights into a p
149 ls, we show that B cells primarily use force-dependent extraction and resort to enzymatic liberation
150 suggest that 5-HT neurons exert a frequency-dependent, cell-type-specific control over BA circuitry
152 implementing GBAi in vivo, we show that GBA-dependent signaling modulates phenotypes during Xenopus
156 quantitative proteomics to characterize Hat1-dependent changes in the composition of nascent chromati
157 tion of the ALOX5 is responsible for the Hcy-dependent worsening of the AD phenotype in a relevant mo
158 ing an infrared laser, for reproducible heat-dependent gene expression in small sublineages (one to f
159 are known to generate a directional helicity-dependent photocurrent in three-dimensional topological
160 ing of the mechanism underlying HBoV1 helper-dependent AAV2 replication may also provide insights int
163 a subset of odor combinations, this history-dependent processing was useful in helping to identify t
164 Sse1sbd was fully competent to support Hsp90-dependent signaling through heterologously expressed glu
168 d humoral immune responses that included IgE-dependent basophil activation and measurement of serum i
171 ol efflux do not necessarily represent inter-dependent events, but MafB is broadly involved in both t
175 The phosphorylation of STAT5B on the JAK2-dependent Y699 site is significantly reduced in the live
179 ification increases receptor tyrosine kinase-dependent activation of RAS more potently in colorectal
180 nal theory calculations, show distinct layer-dependent semiconductor-to-semimetal evolution of 2D lay
182 e epilepsy, alpha-related blood oxygen level-dependent signal changes demonstrated lower decreases re
183 licit greatly exaggerated blood-oxygen-level-dependent (BOLD) responses in the anterior insular corte
185 me 2 (CRY2) can simultaneously undergo light-dependent CRY2-CRY2 homo-oligomerization and CRY2-CIB1 h
186 Stat3-phosphorylation/activation in an LKB1-dependent manner, preventing its recruitment to canonica
187 we demonstrate that key RQC activities-Ltn1p-dependent ubiquitination and Rqc2p-mediated Carboxy-term
190 In an in vitro and cell-based model of MMP-dependent breast cancer cellular invasiveness, this N-TI
192 able RAD51 filament formation prevents MRE11-dependent degradation of the newly synthesized DNA at st
193 ans for interrogating mechanisms of mutation-dependent drug response, which will have a significant i
195 se that phosphorylates MyD88, promoted MyD88-dependent signaling and mediates dermatosis in Ptpn6(spi
196 rameter combinations, which represent myosin-dependent contractility, a characteristic viscosity-adhe
197 ucture of many mineral soils could undergo N-dependent changes as atmospheric CO2 concentrations rise
198 tuin 1 (SIRT1), a conserved mammalian NAD(+)-dependent protein deacetylase, senses environmental stre
200 uses on recent progress on the roles of NFIC-dependent and NFIC-independent signaling pathways in too
203 m Toxoplasma gondii is hydroxylated by an O2-dependent prolyl-4-hydroxylase (PhyA), and the resulting
204 ed one substitution severely impaired OGFOD1-dependent hydroxylation of a neighboring proline residue
206 We report a new distance- and orientation-dependent, all-atom statistical potential derived from s
207 is a member of the Fe (II)- and oxoglutarate-dependent AlkB dioxygenase family and is linked to both
210 e majority of sequences examined display p53-dependent enhancer activity during the DNA damage respon
213 istance, and although expression of the Pap1-dependent genes still relied on stress induction, anothe
214 alpha interaction with PCNA, as well as PCNA-dependent activation of MutLalpha endonuclease, PCNA- an
215 o a cholesterol-rich diet and uncover a PDL1-dependent mechanism through which MZB cells use their in
220 sed by hydrogen bonding to water, where a pH-dependent excitation energy appears to be an intrinsic p
222 significantly inhibited both phosphoantigen-dependent and -independent activation of Vgamma9Vdelta2
225 stimulation also elicited a Ca(2+)- and PKC-dependent reduction in synaptojanin1 recruitment to clat
230 event occurring in the airways of prednisone-dependent asthmatic patients with increased eosinophil a
232 ACD11) in planta and promotes the proteasome-dependent turnover of ACD11 in cell-free degradation ass
234 trols lysosome positioning through Ragulator-dependent, but mTORC1-independent, modulation of BORC.
237 t lung cancer cell lines classified as K-Ras-dependent or -independent for co-dependency on protein k
238 ing as an on-off switch controlling an RbohD-dependent mechanism in response to different stresses, s
239 aint that is mediated by muscarinic receptor-dependent regulation of mitochondrial function via AMPK.
241 ed miRNA expression, we used Cre recombinase-dependent miRNA tagging and affinity purification in mic
243 er-range interactions connecting replication-dependent histone genes on chromosome 6, potentially rep
245 ctivity, supporting the conclusion that RIMA-dependent nuclear IYO accumulation triggers cell differe
246 rt a versatile S-adenosyl-l-methionine (SAM)-dependent enzyme, LepI, that can catalyse stereoselectiv
248 ape this restriction, Gag promotes secretase-dependent cleavage of APP, resulting in the overproducti
252 me proliferator-activated receptor signaling-dependent switch from glycolysis to fatty acid oxidation
254 properties while the latter results in size-dependent mechanical properties at the nanometer scales.
255 est migration in Xenopus embryos in a Snail1-dependent manner, indicating that the mechanism of actio
256 al tubule by the action of the apical sodium-dependent phosphate transporters, NaPi-IIa/NaPi-IIc/Pit2
257 Interestingly, in the absence of sodium-dependent Pi transport activity, the PiT1-PiT2 heterodim
263 a rich extracellular environment in a stage-dependent manner producing complex microstructural patte
264 rate how sensory information regulates state-dependent reflexes in the lower urinary tract and contri
265 distinct signalling mechanisms direct stress-dependent versus homeostatic regeneration, and highlight
267 s as a molecular linker between the synapsin-dependent reserve pool and the presynaptic endocytosis m
269 tion of ERalpha, which in turn increases TAM-dependent anti-estrogen chemosensitivity in vitro and in
271 esults could be accounted for by temperature-dependent changes in both Km and kcat (three substitutio
278 itis B in China, we propose an age- and time-dependent discrete model and use the method of non-linea
281 can be ascribed to an interplay between time-dependent many-particle scattering and phase-space filli
282 n of pressure to the complex causes its time-dependent dissociation and the loss of both DHO and ATC
283 we were able to identify several major time-dependent phenotypic changes in blood immune cell subset
284 nt work by Ezawa; on the calculation of time-dependent gap length distributions in pairwise alignment
288 -level risk factors were analysed using time-dependent Cox regression to examine their potential infl
289 ed that autophagy in NP cells was not TonEBP-dependent; hyperosmolarity did not upregulate autophagy
291 ors, which is a prevailing mechanism for use-dependent inhibition in the nucleus accumbens core and d
292 implicated in mediating several forms of use-dependent plasticity, but the mechanisms by which it con
293 xyketone rearrangement catalysed by vanadium-dependent haloperoxidases to account for these discrepan
295 base of the lamellipodium, where a vinculin-dependent clutch couples actin to previously positioned
296 ene) electrochemical devices exhibit voltage-dependent heterogeneous swelling consistent with device
297 reduced functional expression of the voltage-dependent potassium channel subunit Kv1.1 substantially
299 ranscriptome gene expression analyses on WNT-dependent KDR(+)CD235a(-) definitive hematopoietic mesod
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