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2 The enhanced calcium cycling in the HAX-1-depleted heart was mediated through increases in the cal
6 uction of stalled replication forks in MCL-1-depleted cells, there was a decreased ability to subsequ
7 8-1 rescues impaired secretion in syntaxin-1-depleted PC12 cells and the lethality and lethargy of un
8 in 1, was particularly inhibited in ataxin-3-depleted human cell lines and mouse primary neurons, and
10 ion changes were partially relieved in Ki-67-depleted hTERT-RPE1 cells by codepletion of the Rb check
11 ion of the Abl effector Enabled (Ena) in abl-depleted embryos suppressed the abl phenotype, consisten
12 ight F-actin patch at the tip, whereas actin-depleted neurites never elongated, even though they stil
13 hat an enzymatic release of payload from ADC-depleted human plasma at 144 h was able to account for a
14 s only one enriched protein in the 144 h ADC-depleted and antipayload immunoprecipitated plasma sampl
15 t only reversed sensitization to BSIA in AE2-depleted H69 cholangiocytes but even completely prevente
16 ng the virulence of P. aeruginosa in albumin-depleted versus albumin-rich infection sites and an unde
18 f differential regulation in HSF1-naive and -depleted cells, our results suggest that a large majorit
23 inhibition of nucleotide synthesis in ARID1B-depleted cells results in re-establishment of senescence
28 ioenergetic defects that we observed in BMI1-depleted cells, for example, mitochondrial respiration,
31 d with rapid and massive injections of (13)C-depleted carbon into the ocean-atmosphere system, reflec
33 scopy of (13)C-TBBPA residues bound to (13)C-depleted HA suggested that in the presence of delta-MnO2
34 p Pacific as a major reservoir of this (14)C-depleted carbon, its extent and evolution still need to
36 sical complement pathway using TNT003 or C1q-depleted serum significantly reduced adhesion of monocyt
37 with the C3-inhibitor compstatin Cp40, in C3-depleted human serum, or when purified properdin is appl
39 esicle docking and evoked exocytosis in CAPS-depleted cells, showing that CAPS residence on vesicles
41 erately enhanced compared to that in the Cbl-depleted cells, suggesting that the Cbl-Nectin-1 interac
42 s is demonstrated by the finding that CD301b-depleted mice exhibit delayed wound closure in vivo, whi
43 indlimb tissue, CD34Exo, but not the CD34Exo-depleted conditioned media, mimicked the beneficial acti
44 nza virus split vaccine in CD4KO mice or CD4-depleted WT mice equivalent to those in intact WT mice,
45 ed immunocompetent mice and unvaccinated CD4-depleted mice remained persistently infected with P. mur
53 although not completely protected, mast cell-depleted mice displayed less organ atrophy and fibrosis
54 te cell-wild-type (SC-WT) and satellite cell-depleted (SC-Dep) mice (8 weeks of age) were randomized
55 ensity in both young and aged satellite cell-depleted diaphragm muscle (P < 0.05), which may compensa
56 nsity was maintained in young satellite cell-depleted mice regardless of running, although it was mod
57 l-replete) or tamoxifen (Tam, satellite cell-depleted) treated at 4 months of age and were then allow
58 Patients with leukemia who receive a T cell-depleted allogeneic stem cell graft followed by postpone
61 h transplantation of a "mega-dose" of T cell-depleted peripheral blood hematopoietic progenitor cells
62 activity following haplo-mismatched, T cell-depleted stem cell transplantations for the treatment of
63 tion-free conditioning regimen with a T-cell-depleted graft to eliminate radiation exposure and minim
64 f samples collected from controls and T-cell-depleted macaques after rVSV-EBOV vaccination and EBOV c
67 ghted the importance of the portlandite (CH)-depleted zone and the surface dissolution zone in the CO
69 imulated numerically the evolution of the CH-depleted zone and the dissolution of the cement surfaces
72 be reduced approximately twofold in clathrin-depleted cells as a whole and approximately fivefold in
75 ve imaging of meiotic divisions in condensin-depleted cells showed repeated nuclear stretching and co
81 nriched bone marrow cells into septic Cx3cr1-depleted mice prevented kidney damage and promoted mouse
82 ore, raising serum calcium levels in Cyp27b1-depleted mice directly increased FGF23 levels and indire
86 mikimotoi were set up in L1 medium (+P), DIP-depleted L1 medium (-P) and ATP-replacing-DIP medium (AT
89 sal striatum of dopamine-intact and dopamine-depleted rats during two brain states, respectively defi
90 g GPe neurons, restores movement in dopamine-depleted mice and attenuates pathological activity of ba
98 hECTs with exosome-enriched, but not exosome-depleted, fractions of the hMSC secretome recapitulated
100 recovered from control but not C-NHEJ factor-depleted cells, providing important mechanistic insights
102 hanistically, we demonstrated that, in FANCM-depleted ALT cells, BRCA1 and BLM help to resolve the te
103 restore EPA-induced Ucp1 expression in Ffar4-depleted cells, implicating that Ffar4 signaling activit
106 ol BM monocytes, BM monocytes from gut flora-depleted mice had decreased migratory capacity toward CX
107 e of chem163S, which was undetectable in FXI-depleted plasma and markedly enhanced in platelet-rich p
110 (P) signaling cascade, was diminished in GIV-depleted cells, suggesting that GIV is required to estab
111 Examination of the Kupffer's vesicle in Gle1-depleted zebrafish revealed compromised ciliary beating
112 thods, glycopeptide-enriched and beta-glucan-depleted products were each prepared from Brewer's and B
113 promoters of beta-oxidation genes in glucose-depleted conditions, and in vivo reporter gene analysis
114 by enhanced phagocytosis of Klebsiella GPVI-depleted mice showed increased lung hemorrhage during in
123 sfer and the upshift in the Em of QA HCO3(-)-depleted PSII also showed diminished light-induced (1)O2
124 ization and greater lipid oxidation in HDAC3-depleted muscles, a fuel switch caused by the activation
125 d to HemW was actively transferred to a heme-depleted, catalytically inactive nitrate reductase, rest
130 ConA was administered i.v. to control or HSC-depleted mice; hepatic histopathology and cytokines/chem
132 HSCs into cycle, was well tolerated by HSPC-depleted mice and did not induce expansion of the small
133 Only upon 5-fluorouracil treatment was HSPC-depleted bone marrow compromised in reconstituting hemat
134 Whereas AID levels were not altered in Id3-depleted activated B cells, the expression of a subset o
140 or ((58)Fe)-labelled ferrous sulfate in iron-depleted (serum ferritin </=25 mug/L) women aged 18-40 y
141 s HLIIIA and HLIVA ESTUs codominated in iron-depleted areas of the Pacific Ocean, CRD1 and the yet-to
142 ruginosa mutants defective in growth in iron-depleted media and find that gene PA2374, proximal to th
144 At the end of the study, comparison of iron-depleted patients and controls showed ferritin levels 71
145 tional iron status measures.Seventy-two iron-depleted, nonanemic Chinese women [serum ferritin (sFer)
147 to differentiation culture conditions, Kdm5b-depleted adult NSCs migrated from neurospheres with incr
150 ression of Kras(G12D) were crossed with Lcn2-depleted animals and fed isocaloric diets with varying a
154 RNA was obtained, as expected, from the LK14-depleted population, but was also in sIgkappa(+) splenoc
156 selection patterns in non-CD8(+) lymphocyte-depleted animals were characterized by sequential popula
157 odel with SIV-infected non-CD8(+) lymphocyte-depleted macaques also provides a unique opportunity to
163 protein mice) transplantation in bone marrow-depleted IL10KO mice (IL10KO chimeric mice) reduced tran
164 is a complex process in which the melanocyte-depleted interfollicular epidermis is repopulated by mel
166 observed this contribution under methionine-depleted conditions, unexpectedly, we found that serine
169 rom vehicle-gavaged NOD donors to microbiota-depleted C57BL/6 recipients was sufficient to induce soc
171 vate ratio at the injury cortex of microglia-depleted animals at 7 days post-injury remained unchange
172 Zeb2, and Snail2 are upregulated, and miRNA-depleted CDs undergo partial epithelial-to-mesenchymal t
176 to generate Parkin-expressing, mitochondria-depleted cells from scratch in 23 d, as well as offer a
177 culture conditions to maintain mitochondrial-depleted cells for up to 30 d with minimal loss of viabi
179 NP overexpression rescues furrowing in MKlp2-depleted cells in an INCENP-actin binding-dependent mann
180 Reconstituting RELMalpha in CD301b(+) MNP-depleted animals restored body weight and normoglycemia.
182 itochondrial electron transport chain, mtDNA-depleted cells still maintain mitochondria and many mito
185 a result of this secretory blockade, Munc18c-depleted acini unexpectedly activated a component of the
186 we found that pancreatic acini from Munc18c-depleted mice (Munc18c(+/-)) and human pancreas (lenti-M
187 CCK-8 levels to mimic pancreatitis, Munc18c-depleted (Munc18c(+/-)) mouse acini exhibited a reductio
188 affecting pluripotency, suggesting that Myc-depleted stem cells enter a state of dormancy similar to
189 lk1 itself (self-priming) increased in MYPT1-depleted cells showing that MYPT1 provides a molecular l
190 ng that N deposition in the region is (15) N-depleted, these data suggest that the increased foliar [
191 s to the occurrence of phosphorus-bearing, N-depleted surface waters, which encourages N2 fixation, t
192 matin immunoprecipitation assays from NAP1L1-depleted cells showed LANA-mediated recruitment of NAP1L
193 ies the formation of a complementary (142)Nd-depleted reservoir that either is hidden in the deep Ear
195 icient, lymphocyte-deficient, and neutrophil-depleted murine hosts revealed that neutrophil-phage syn
196 of K. pneumoniae is preserved in neutrophil-depleted mice, monocyte depletion or TNF deficiency impa
198 juice) compared with placebo intake (nitrate-depleted beetroot juice) on vascular and platelet functi
200 cularity, increased CTL infiltrate, and Nrp1-depleted BMDM adopted a more antitumorigenic phenotype r
201 hage populations of wild-type mice with Nrp1-depleted bone marrow-derived macrophages (BMDM) confers
204 s binding, while the well-defined Nucleosome-Depleted Regions (NDRs) marked the genes crucial for cel
205 es occupies previously designated nucleosome-depleted regions around transcription start sites and tr
206 that bivalent regions have fewer nucleosome-depleted regions and transcription factor-binding sites
207 chromatin, with faster repair in nucleosome-depleted regions, and slower repair and higher mutation
208 utionarily conserved signature of nucleosome-depleted regions around transcription start/termination
209 ur findings show that regulatory, nucleosome-depleted chromatin and elevated transcription shape the
211 es (TSSs) are bordered by a small nucleosome-depleted region, but lack the stereotypic downstream nuc
213 mplying that the west Pacific was a nutrient-depleted environment and that oligotrophy may have facil
214 igher than in iron-rich coastal and nutrient-depleted oligotrophic waters, and were dominated by amph
215 ce of relatively young, very dense, nutrient-depleted water during the LGM (18 ky to 21 ky ago).
217 t and dry soil moisture conditions to (18) O-depleted water vapour (c. - 200 per thousand) at high re
221 exhibit diminished H3K9 methylation in ORCA-depleted cells, suggesting a role for ORCA in recruiting
225 m amyloid P replenishment of serum amyloid P-depleted acute respiratory distress syndrome broncho-alv
226 expression profiling of p53-mutated and p53-depleted cancer cells, we identified ectonucleoside trip
227 f methylation-deficient p53 mutants into p53-depleted NTera2 cells results in elevated expression of
228 ve role for the microbiome, treatment of pDC-depleted neonates with the microbial-derived metabolite
229 proteomics and informatic analyses of PEAK1-depleted PDAC cells, we defined protein translation, cyt
231 utant was significantly reduced in phosphate-depleted medium, while growth was only marginally affect
234 , but not to the extent observed in platelet-depleted mice, and lung bleeding was not significantly d
238 reover, orthotopic implantation of PR55alpha-depleted pancreatic cancer cells into nude mice resulted
239 has been mostly injected back into pressure-depleted oil-producing reservoirs for enhanced oil recov
243 ivo studies demonstrating that in Tum/RacGAP-depleted S2 Drosophila cells, Pav/kinesin-6 exhibits sev
244 likely the primary source of the radiocarbon-depleted CO2 released to the atmosphere during the last
251 ripts in expression quantification from rRNA-depleted RNA-seq data showed substantial increased accur
254 e water-deprived but not under food- or salt-depleted conditions, indicating that the hedonic value o
256 ophores are able to outcompete diatoms in Si-depleted waters, which can contribute to the formation o
257 t and successful congression, whereas in Ska-depleted cells, detached kinetochores remain in a futile
259 progression, and the loss of E2F1 in SmgGDS-depleted cells provides an explanation for previous repo
263 helial tumor cells coxenografted with Snail1-depleted fibroblasts originated tumors with lower invasi
264 ha-SNAP with Stim1 and Orai1, and alpha-SNAP-depleted cells show faster and less constrained mobility
265 ed in Sirt3-knockout (Sirt3(-/)(-)) and SOD2-depleted (SOD2(+/)(-)) mice in response to low dose of a
267 ng strongly drives sodium appetite in sodium-depleted mice, whereas a role for kappa (KOR) and delta
269 oalescence that promote homogeneous, species-depleted landscapes; and (g) deliberate culture and rele
270 e presynaptic structures in betaIII spectrin-depleted neurons make shaft synapses that exhibit increa
277 acks an explanation for the origin of sulfur-depleted organic matter in the deep ocean and cannot ade
279 ranscription decreases for genes in the Taf1-depleted, Taf1-enriched, TATA-containing, and TATA-less
280 By contrast, ER/Golgi defects in Tango1-depleted cells persist in the absence of bulky cargo, sh
284 hat B-cell lymphopoiesis is impaired in Treg-depleted mice, yet this reduced B-cell lymphopoiesis is
286 reduced ROS and preserved viability of TRPM2-depleted cells, however, failed to restore ATP levels.
290 ency resolution, Utx-null mouse ESCs and UTX-depleted NT2/D1 cells displayed defects in RA-driven cel
291 istent with these results, we found that Ver-depleted telomeres form RPA and gammaH2AX foci, like the
292 entrifugation in the preparations of vesicle-depleted FBS (vdFBS) commonly utilized in the studies of
295 their crystallization, confirming a volatile-depleted lunar interior source with homogeneous delta(66
298 genes that are required for viability of WRN-depleted cells after hydroxyurea treatment, and identifi
299 Microarray analysis of IRE1alpha- and XBP1-depleted cells, validation using RNA cleavage assays, an
300 xyloglucan was allowed to bind to xyloglucan-depleted onion walls, CBM76 labelling gave positive evid
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