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1 ture and has a much higher (4,000- to 20,000-fold increased) particle-to-PFU ratio in vitro than herp
2 uli (P = .0009), with an average 1.7- to 2.1-fold increase in levels of several proinflammatory cytok
3 sis showed 4.9- to 7.1-fold or 22.5- to 28.1-fold increase in FVIII or VP1 codon-optimized genes when
4 eachates was enhanced as indicated by a 2-10-fold increase in distribution coefficients for individua
5 meta-analysis of four studies estimated a 10-fold increase (in other words, times 10) in PBDE exposur
9 After adjusting for various covariates, a 10-fold increase in hepatic triglyceride content was associ
11 itamin A deficiency was associated with a 10-fold increase in risk of tuberculosis disease among HHCs
12 hyperkalemia on a high-K+ diet, despite a 10-fold increase in serum aldosterone levels, implying that
14 e monodisperse and to display more than a 10-fold increase in spikes per particle by electron microsc
16 naerobic to aerobic conditions leads to a 10-fold increase in volume-specific mineralization rate, il
18 nt reduction in Galphaq binding affinity (10-fold increase in Ki compared with WT RGS2 in a flow cyto
21 is number rises by a factor of 7 for each 10-fold increase in the population of the "enclosed" region
23 n 50% mortality and caused a significant >10-fold increase in the number of parasitic female worms co
24 ficant increases in lymphoma in both men (10-fold increase, P < .001) and women (8.34-fold increase,
25 (CD73(f/f)Villin(Cre) ) revealed a nearly 10-fold increase in colonization compared to that in contro
26 n of disease (hazard ratio [HR], 0.82 per 10-fold increase in abundance; 95% CI, 0.71 to 0.95; P = .0
27 143; 95% CI: -0.248, -0.039, p=0.008) per 10-fold increase in the estimated amount of sulfur used wit
28 sing (exp-inc) dosing profiles eliciting >10-fold increases in antibody production relative to bolus
29 ts, we designed biosensors that attain a 100-fold increase in fluorescence upon binding to analyte, a
33 P for tissue labeling; this resulted in >100-fold increase in labeling speed in both mice and Drosoph
35 rgan transplant recipients (OTRs) have a 100-fold increased risk of cutaneous squamous cell carcinoma
36 m, or [(18)F]FPTMP, shows a greater than 100-fold increased uptake in vitro in live bacteria (Staphyl
38 and C-terminus of Cl-amidine result in >100-fold increases in PAD2 potency and selectivity (30a, 41a
41 of BK viremia of 3 months or less, had an 11-fold increase in frequency of CD8+ polyfunctional T cell
42 e men and those in manufacturing had an 8-11-fold increased risk of lung, gastric and colorectal canc
43 risk genotypes had an approximately 3- or 11-fold increased risk of SCCOP recurrence, respectively.
44 In wheat cells, the replicons achieve a 110-fold increase in expression of a reporter gene relative
45 ganic dye (CH-4T) to produce a brilliant 110-fold increase in fluorescence, resulting in the highest
46 al reperfusion, with a 2.45-, 3.17- and 2.12-fold increase in ATP:ADP, ATP:AMP and energy charge afte
49 rn blots showed 6.3- to 8-fold or 91- to 125-fold increase of transgene expression from the same batc
50 e, anticoagulation was associated with a >13-fold increased risk of hemorrhage (HR, 13.26; 95% CI, 3.
53 ve fHb concentrations of 8 mug Hb/g had a 14-fold increase in risk of AN compared with participants w
54 h qSOFA scores of 2 or higher had a 3- to 14-fold increase in hospital mortality across baseline risk
55 ion of 4044 more unique proteoforms and a 15-fold increase in the detection of proteins above 60 kDa,
56 llomer hydroxychlorophyll a peaked with a 16-fold increase (relative to chlorophyll-a) just after the
57 pro-self-renewal phenotypes, including a 17-fold increase in short-term repopulating cells and a net
58 rrolo[2,3-d]thiazole 23c possessing up to 17-fold increase in metabolic half-lives in HLMs and good i
60 ollowed, with lags of 1-3 years, by 3- to 19-fold increased abundances of five ocean-produced demersa
61 ed from 10 days postoperatively (2.4 +/- 0.2-fold increase, P < 0.01), and GLP-1 peak increased 3.8 +
62 those in the highest stress group had a 2.2-fold increase in risk of either receiving triple treatme
67 phosphate phosphatase type 1 (PLPP1) had a 2-fold increase in endogenous LPA levels, reduced PEPCK le
68 ied with 4-pyridinylethanemercaptan show a 2-fold increase in Faradaic efficiency and 3-fold increase
69 both humans and rodents, they experience a 2-fold increase in mood disorder prevalence vs. males.
71 ioning lesion, C3(-/-) mice demonstrated a 2-fold increase in sensory axon regeneration in the spinal
72 ent with these biochemical observations, a 2-fold increase in the expression level of wild-type PFN1,
74 osure, azithromycin caused a approximately 2-fold increase in both peak and late SCN5A currents, with
75 plemented mutant exhibited a approximately 2-fold increase in cmr expression, which led to increased
76 efore pregnancy and was associated with a >2-fold increase in the risk of offspring obesity at ages 6
77 eir reprogramming in vivo in D6(+/+) mice (2-fold increase in IL-10/IL-12 ratio) but not their D6(-/-
78 ed rate of binucleation there was a nearly 2-fold increase in the number of cardiomyocytes in mitosis
79 , fibroblasts carrying the mutation showed 2-fold increase in proliferation rate associated with hype
80 cific promoter, we achieved a greater than 2-fold increase in iron in white flour fractions, exceedin
81 G. pulex video-tracking suggested that the 2-fold increase in bioaccumulation, and, thereby, the rais
82 1% decrease in volume was associated with 2-fold increase in odds of worsening SMR over time (OR 2.1
83 d odds of ILAs (95% CI = 1.1-2.1), and a 2.2-fold increased all-cause mortality rate (95% CI = 1.9-2.
85 ring with PTEN germline mutations confer a 2-fold increased prevalence (OR 2.7) of thyroid cancer com
86 ase in future incident heart failure and a 2-fold increased risk in coronary heart disease, stroke, a
87 risk-increasing foods is associated with a 2-fold increased risk of all-cause mortality.Selecting spe
88 omen with at least 2 episodes of PID had a 2-fold increased risk of borderline tumors (pOR = 2.14, 95
90 evels were associated with a approximately 2-fold increased risk of future cardiovascular events and
92 management was associated with a more than 2-fold increased risk of death from GISTs (subdistribution
94 ribution was also significantly (1.7 +/- 0.2-fold) increased (VT, 0.38 +/- 0.033 mL/cm(3), P < 0.05),
95 onds to DNA duplex formation with up to a 20-fold increase in fluorescent quantum yield as compared w
96 The measured enzyme kinetics revealed a 20-fold increase in the cleavage rate for the Gly1629Glu mu
100 NMR spectroscopy approach that induces a 200-fold increase in the NMR sensitivity for the surface spe
102 s by 99.995% and achieves a greater than 200-fold increase in dynamic range of detection compared to
103 n in infants of diabetic mothers, with a 200-fold increased risk as compared to the general populatio
105 the presence of eculizumab, there was a >22-fold increase in geometric mean CFUs per milliliter (90
106 tial for noncentrosymmetric structures, a 25-fold increase in the projected number of known noncentro
107 tion syndrome (22q11DS) have an estimated 25-fold increased risk for schizophrenia spectrum disorders
108 off for 30 seconds, there was a more than 26-fold increase in particulate count compared with ambient
110 ed strain grew 50% slower and displayed a 27-fold increase in the rate of mistranslation of Phe codon
114 and a G1/S block that translated into a 2-3-fold increase in tumor cell doubling time without increa
117 n-binding affinity, with a approximately 3.3-fold increase after 1 h for the high FcRn-binding albumi
118 s capable of harboring HIV-1, a 1.7- and 3.3-fold increase in mean CD4+ T-cell-associated HIV-1 RNA a
120 plaque was independently associated with a 3-fold increase in atherosclerotic cardiovascular disease
121 enes encoding AAOs and ADD, resulting in a 3-fold increase in enzymatic activity of AAOs, as well as
124 with 135-144 mEq/L) was associated with a 3-fold increase in the odds of mild (stage 1) AKI (aOR, 3.
127 s with CLF from HCV or ALD, with an almost 3-fold increase in percentage of patients with CLF from NA
128 panied by an increase in ADP/ATP ratio and 3-fold increase in AMPK activity, indicating energetic str
129 zard ratio [HR], 5.0; 95% CI, 2.8-8.7) and 3-fold increase in CVD events (HR, 3.0; 95% CI, 1.9-4.7).
130 2-fold increase in Faradaic efficiency and 3-fold increase in formate production relative to Au foil.
131 PE that is associated with a approximately 3-fold increase in bumetanide-sensitive CSF secretion.
132 United States would result in an estimated 3-fold increase in measles cases for children aged 2 to 11
133 -) mice on chow diet, with a further 2- to 3-fold increase on Western diet (22-fold over healthy).
135 rding to UO criteria (AKI-UO) had nearly a 3-fold increased rate of hospital mortality compared with
136 2); high-risk plaque was associated with a 3-fold increased risk of atherosclerotic cardiovascular di
138 A patchy distribution portended to a near 3-fold increased hazard to MACE (HR: 2.93; 95% CI: 1.79 to
139 inked cancer was associated with more than 3-fold increased risk in subsequent mortality until the th
140 els of proinflammatory cytokines and 2- to 3-fold increased expression levels of inflammatory mediato
141 The results showed significant 2.9- to 5.3-fold increases in average post-event levels of urinary P
145 infection by the wild-type strain (with a 30-fold increase in the number of colony-forming units/mL;
146 , mDA neurons generated in 3D exhibited a 30-fold increase in viability upon implantation into rat st
151 old increase in proliferative ECs and a 1.35-fold increase in proliferative alpha-smooth muscle actin
152 es of over 9 mAh cm(-2)areal , which is a 35-fold increase in capacity compared to without phenol.
153 n a high-sugar diet, Irf6 cKO mice show a 35-fold increase in presentation and severity of dental car
155 e in extracellular acidification rate, a 1.4-fold increase in lactate production, and overexpression
156 , although Rab10 knockdown also caused a 1.4-fold increase in the rate constant of Glut4 endocytosis
157 copy of IGHV4-61*02 is associated with a 1.4-fold increase in the risk of RHD (odds ratio 1.43, 95% c
160 il in dissolved organic carbon (DOC) and a 4-fold increase in 5-day biochemical oxygen demand (BOD5).
163 evaluated for seroconversion, defined as a 4-fold increase in immunoglobulin G directed against Crypt
164 imal growth temperatures, they exhibited a 4-fold increase in the expression of class I chaperone gen
165 Finally, ccr1 ProSNBE:CCR1 plants had a 4-fold increase in total sugar yield when compared with wi
166 nized into hundreds of clusters (roughly a 4-fold increase since the last version of the ATGC databas
167 ty of the 53 paired sera demonstrated a >/=4-fold increase in antibody titer against the infecting ty
168 nd that 9 of 17 (53%) paired sera had a >/=4-fold increase in antibody titer to cluster-related strai
170 a hemagglutination titer >/=1:40 plus a >/=4-fold increase over T0 at 3 wk postvaccination were desig
172 = .02) and TLR9 (P = .02), a greater than 4-fold increase in IL-17A (P = .03) production after polyc
173 ugs use during ARI was associated with a 3.4-fold increased risk of AMI (adjusted odds ratio [aOR] =
174 nfidence interval, 1.10-7.7, P=0.03) and a 4-fold increased risk of stroke (hazard ratio, 4.43; confi
176 exhibited reduced alveolar bone height and 4-fold increased numbers of osteoclast-like cells versus w
177 ysis of Enpp1 mutant mouse molars revealed 4-fold increased acellular cementum thickness ( P = 0.002)
178 rimary teeth from 3 GACI subjects revealed 4-fold increased cervical cementum thickness ( P = 0.00007
179 e crosslinked SCRII showed over 6-fold and 4-fold increases, respectively, in activity and k cat/K m
180 d microparticles (MCMs), we observed up to 4-fold increases in transfection efficiency with simultane
181 ed in doubly deficient recipients, with a 40-fold increase compared with wild-type recipients at day
183 lows a 30-fold longer reaction time and a 40-fold increase in pressure compared to standard PTR-TOF-M
184 crylate) chains resulted in approximately 40-fold increase in activity over lyophilized enzyme powder
185 ouring BRCA1/2 mutations demonstrate a 30-40-fold increased risk of high-grade serous extra-uterine M
186 at meiotic onset, the transgene showed 1,400-fold increase in RNA expression and consequently 70-fold
188 urrence (n = 6,169) was associated with 1.44-fold increased risk [95% confidence interval (CI), 1.31-
189 ed 19-fold greater tumor accumulation and 46-fold increase in per-tumor-cell uptake in a mouse orthot
190 t quartile of a 127-variant score had a 2.49-fold increased odds of cardioembolic stroke (95% confide
191 ulatory stage was characterized by 3 x 10(5)-fold increases in volume, decreases in roundness, and de
193 n after injection of the tracer showed a 2.5-fold increase in metabolic stability of (18)F-4FMFES ove
194 ssociations resulted in between 1.5- and 2.5-fold increase in the proportion of heritability explaine
196 s identified on CT, with a corresponding 2.5-fold increase over baseline for both PET radiotracers.
197 and time, prior BV was associated with a 3.5-fold increase in odds of incident M. genitalium (adjuste
198 duced CDKN2A expression coincided with a 4.5-fold increase in ETS1 (ETS proto-oncogene 1) mRNA, sugge
199 ion by supramaximal CCK-8, and despite a 4.5-fold increase in total cellular trypsinogen levels, are
200 9 months to a maximum of a approximately 5.5-fold increase after 36 months, compared to the parent MW
203 eatments, those with any CAC experienced a 5-fold increase in CHD events (hazard ratio [HR], 5.0; 95%
204 ables based on the current expanded PDB (a 5-fold increase in information), and introduced new residu
206 therosclerotic plaque formation, despite a 5-fold increase in plasma adiponectin level compared with
207 and growth factor treated cartilage gave a 5-fold increase in stiffness correlating with a 10-fold up
208 ed with >/=10 mEq/L) was associated with a 5-fold increase in the odds of severe (stage 2 or 3) AKI (
210 exertional dyspnea (95% CI = 1.3-1.9), a 1.5-fold increased odds of ILAs (95% CI = 1.1-2.1), and a 2.
211 nd NSAIDs use only was associated with a 1.5-fold increased risk (aOR = 1.47; 95% CI = 1.33-1.62).
213 and those with >/=2 of the factors had a 4.5-fold increased OR for MAC-PP relative to the comparison
214 arker of reduced survival after ASA with a 5-fold increased risk of all-cause mortality in patients w
215 llular cementum thickness ( P = 0.002) and 5-fold increased cementum volume ( P = 0.002), with no cha
216 3-fold improved half-life at 60 degrees C, 5-fold increased specific activity at 65 degrees C, 1.3-fo
217 reas the R655C mutation decreased the EC50 5-fold, increased the Vmax 2.1-fold, and decreased the Km
218 The A488P mutation decreased the EC50 5-fold, increased Vmax 2.6-fold, and decreased the Km 13-f
221 , URMC-099 activation of autophagy led to 50-fold increases in the plasma drug concentration of the v
222 reference genome, our assembly features a 52-fold increase in contig length and notable improvements
223 rived mesenchymal stem cells, displayed a 55-fold increase in the expression of hepatocyte growth fac
224 the new criteria was associated with a 2.58-fold increase in the rate of overwork-related CVDs (p-va
226 isone dose is associated with a 1.5- and 2.6-fold increase (P < 0.001 and P < 0.001) in the rate of c
227 jects with essential hypertension showed 2.6-fold increase in SOD2 acetylation and 1.4-fold decrease
228 Mass spectrometry analysis detected a 4.6-fold increase in total hepatic bile acid levels, despite
229 ld increase in circulation half-life, an 8.6-fold increase in bioavailability, and reduced renal accu
231 hat chenodeoxycholic acid (CDCA) induced a 6-fold increase in ATF4 expression and that knockdown of A
232 in relation to the control, followed by a 6-fold increase in TB14 rats, whereas de novo lipogenesis
233 o 12k by MS alone), with instances of over 6-fold increase in the number of molecular features per no
235 confidence interval [CI] = 0.9-6.6%), a 1.6-fold increased odds of exertional dyspnea (95% CI = 1.3-
236 th translational enhancers, display up to 64-fold increase in sensitivity over first-generation reage
237 itchable transport properties with up to 640-fold increase in transport efficacy on going from pH 7.2
238 presentation bisulfite sequencing, with a 66-fold increase in the fraction of consistently profiled C
241 rison with unmodified siRNA, exhibited a 5.7-fold increase in circulation half-life, an 8.6-fold incr
245 without NSAIDs use was associated with a 2.7-fold increased risk (aOR = 2.65; 95% CI = 2.29-3.06), an
246 cgammaRIIIa-expressing NK cells, a 12- and 7-fold increased erythrocyte lysis was observed with the I
247 approximately 2.2-fold and approximately 1.7-fold increases in proliferation on day 14, respectively,
248 -, approximately 5.1-, and approximately 6.7-fold increases in col Ialpha 1, sox 9, and aggrecan gene
249 crease in RNA expression and consequently 70-fold increase in retrotransposition in postnatal day 14
252 with irradiated perchlorates to cause a 10.8-fold increase in cell death when compared to cells expos
255 in a synergistic fashion, resulting in an 8-fold increase in oxacillin potency, for a MIC of 16 mug
256 s with low diversity, we observed an up to 8-fold increase in insecticide tolerance in a total of 17
258 mutations are associated with modest 2- to 8-fold increases in MICs for BDQ and clofazimine, whereas
259 of three or more codons conferred at least 8-fold-increased ganciclovir resistance, while the level o
260 ociated with a 1.81-, 2.59-, 6.17-, and 8.80-fold increase, respectively, in the risk of death and my
261 Elacridar infusion resulted in a 3.5 +/- 0.9-fold increase in (11)C-erlotinib distribution to the bra
263 lead release by 531 mug L(-1) on average-a 9-fold increase over uniform corrosion in the absence of i
264 g risk models, PVD was associated with a 1.9-fold increased risk of mortality (95% confidence interva
265 loss (P = 0.001; odds ratio, 8.4) and a 2.9-fold increased risk of 30-day mortality after LT in a ca
266 duces isoalkanes with 100% selectivity and 9-fold increased mass activity as compared to a more tradi
270 offers high sensitivities, achieving a four-fold increase in the supported number of subscribers and
272 through air would have conferred a 1 million-fold increase in the amount of space within which object
273 the Americas has been accompanied by a multi-fold increase in reported incidence of fetal microcephal
281 contrast, S. melilutra models exhibit a six-fold increase in stiffness from expected stiffness-volum
282 sample tubes are filled may result in a ten-fold increase in sample haemolysis, compared to the reco
285 riants to low-pH fermentations, enabling ten-fold increased production of lactic acid compared to tit
286 t the particle transport experienced a three-fold increase when compared with the traditional setup.
287 he Janus catalyst exhibits a more than three-fold increase in catalytic efficiency compared to the Pt
288 n-smokers is associated with a two- to three-fold increase in the odds of developing periodontitis.
294 in vitro migration assay demonstrated a two-fold increase in the migratory potential of HA-treated M
295 dose was evaluated, there was an almost two-fold increase in lung cancer risk among men in the highe
296 These results are ascribed to at least two-fold increase in the concentrations of flavonoids, spath
298 d phase-conjugated nanostructures showed two-fold increase in diffracted light intensity under monoch
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