ライフサイエンスコーパス: -independent

1 Using a PECAM-1-independent transwell system, we found that CD177(pos) a

2 omal degradation, and induction of a Bet v 1-independent T-cell response.

3 otential leading to the activation of Ca(2+)-independent phospholipase A2gamma (iPLA2gamma) and the p

4 IL-27- and IL-35-independent functions of EBI3 could compromise its thera

5 hate nucleotidohydrolase in an interleukin 6-independent manner.

6 ent resistance; however, overcoming BCR-ABL1-independent mechanisms of resistance remains challenging

7 dent pathways, and monomeric alphaS by actin-independent pathways.

8 r, this functional separation reveals action-independent coding of declarative memory-based familiari

9 specificity and inhibits Src in an activity-independent manner.

10 l modes during cytokinesis: a motor activity-independent form that can promote actomyosin ring assemb

11 y and likely temporally overlapping activity-independent and activity-dependent modes of myelination

12 n both substrate recruitment and S-acylation-independent functions, was recently shown to bind at lea

13 They also reveal a novel SAP adaptor-independent function for a SLAM receptor.

14 -hemispheric counterparts seems to be an age-independent domain-general strategy to master cognitive

15 It may represent an age-independent mutational mechanism that contributes to the

16 activation by phorbol ester induced agonist-independent KOPR phosphorylation.

17 C activation caused a lower level of agonist-independent KOPR internalization, compared with U50,488H

18 This suggests that upon agonist-independent internalization, GPRC6A is recycled via the

19 ngs underscore the clinical relevance of AKT-independent pathways in tumors driven by genetic lesions

20 lpha-induced CFB expression, suggesting AMPK-independent effects.

21 Both amyloid- dependent and amyloid-independent pathological profiles can be identified in t

22 roduce cognitive decline, and drives amyloid-independent brain atrophy during the earliest stage of d

23 ntifies both ancestry-dependent and ancestry-independent contributions to SLE risk.

24 roliferation, colony formation and anchorage-independent cell growth.

25 Aspirin decreased viability and anchorage-independent growth of mutant PIK3CA breast cancer cells

26 e doubling times, cytokinesis, and anchorage-independent growth.

27 ssion of CD24 (NLS-CD24) increased anchorage-independent growth in vitro and tumor formation in vivo

28 cer cells from self-renewing under anchorage-independent conditions, whereas ectopic overexpression o

29 inhibited both phosphoantigen-dependent and -independent activation of Vgamma9Vdelta2 T cells and, im

30 We assessed neuronal-dependent and -independent contributions by activating or inhibiting ne

31 riking impairment of clathrin-dependent and -independent endocytosis in proximal tubules, phenocopyin

32 markers of tricarboxylic acid-dependent and -independent energy biogenesis and oxygen consumption in

33 nt survival of both endocrine-dependent and -independent ER+ tumors.

34 r efforts uncover replication-dependent and -independent ICL repair networks, and establish nematodes

35 to facilitate both recycling-dependent and -independent iron uptake.

36 y essential genes between Ras-dependent and -independent lines uncover synthetic lethal partners of o

37 MDM2, which acts through p53-dependent and -independent mechanisms to abrogate checkpoints that prev

38 tance to TKI through BCR-ABL1-dependent and -independent mechanisms.

39 uritic against both histamine-dependent and -independent pruritogens, but the therapeutic window usin

40 1 and ETR2 have both ethylene-dependent and -independent roles in plant cells that affect responses t

41 rial infusions of endothelial-dependent and -independent vasodilators were measured.

42 n to block cancer progression in an androgen-independent manner.

43 ssed in both androgen-dependent and androgen-independent prostate cancer (PCa) cells, whereas CLK2 an

44 ng demonstrate strong selection for androgen-independent cells and rapid treatment failure.

45 cycles, suppresses proliferation of androgen-independent cells and lowers cumulative drug dose.

46 haracter or minor subpopulations of androgen-independent cells that are poised for clonal selection a

47 itumor effects of miR-1 and promote androgen-independent proliferation.

48 on as well as cell proliferation and anoikis-independent growth, which is mediated by the gene produc

49 of CSF Abeta were assessed using an antibody-independent mass spectrometry-based reference measuremen

50 report a novel strategy, integrating antigen-independent subtraction enrichment and immunostaining-FI

51 AR)-dependent luminal epithelial cells to AR-independent basal-like cells.

52 Th1 and Th17 differentiation in an aromatase-independent fashion, but also exacerbated cell death in

53 ptors, but does not affect the beta-arrestin-independent Erk1/2 activation by 5-HT4 receptor.

54 idepressants by an uncharacterized, arrestin-independent mechanism.

55 oliferation and invasion, suggesting an ATGL-independent role of ABHD5 in modulating PCa aggressivene

56 ATP-independent endocytosis became more significant at 34-35

57 ATP-independent endocytosis primarily involved retrieval of

58 Rev in a dose-dependent manner, although ATP-independent helicase activity is not.

59 An ATP-independent form of endocytosis was recruited to acceler

60 more, DDX21 is both an ATP-dependent and ATP-independent helicase, and both ATPase and ATP-dependent

61 e complex to explore ATRX-dependent and ATRX-independent functions of DAXX.

62 fs plants, suggesting that additional, auxin-independent regulation is needed.

63 ource.Some aerobic bacteria contain a biotin-independent malonate decarboxylase (MDC), which allows t

64 ies and other aerobic bacteria have a biotin-independent malonate decarboxylase that is crucial for t

65 osolic metabolic roles and a distinct biotin-independent nuclear coregulatory function.

66 lizing the midcell Z-ring through a bundling-independent mechanism.

67 the PDF receptor, the former through a cAMP-independent mechanism and the latter through a cAMP-PKA

68 Thus, cAMP-independent signals contribute to the induction of hypha

69 new role for the helicase complex in 3' cap-independent translation element-mediated translation and

70 somes to increase protein synthesis in a CAP-independent manner.

71 ns of AR and mTOR inhibitors by inducing cap-independent translation.

72 ic proteome and revealing novel modes of cap-independent translation.

73 istant translatomes is incompatible with cap-independent translation mediated by internal ribosome en

74 were important for suppression of a caspase-independent cell death and the long-term survival of FA-

75 or cells in which autophagy promotes caspase-independent cell death, ATG16L1 maintains the intestinal

76 AML patient survival and allows beta-catenin-independent transformation in MLL-CSCs derived from hema

77 corporated into cells via sortilin or cation-independent mannose 6-phosphate receptor, and facilitate

78 -Golgi network (TGN) transport of the cation-independent mannose 6-phosphate receptor (CI-MPR).

79 The results support the notion that CD19-independent factors drive early B cell mobilization and

80 cells or a unique subset of innate-like CD1d-independent T cells.

81 ecific IgM Abs upon immunization with T cell-independent Ags, and they are more susceptible to Gram-n

82 plenic MZ and play important roles in T cell-independent humoral immune responses against blood-borne

83 es, are thought to mainly derive from T cell-independent innate B cell subsets.

84 its T cell expansion via a regulatory T cell-independent mechanism that involves caspase-dependent T

85 es and switched to IgA in response to T cell-independent or T cell-dependent signals.

86 ns and an intact immune response to a T-cell-independent antigen, their response to a T-cell-dependen

87 5), required for AURKA-dependent, centrosome-independent mitotic spindle assembly is essential for th

88 NO also appears to function in a cGMP-independent manner, via S-nitrosation (SNO), a redox-bas

89 Surprisingly, we observed calcium channel-independent effects on microglia, resulting in apoptosis

90 ic cause of juvenile or late-onset and cilia-independent NPH.

91 behaviors in a light-dependent but circadian-independent manner.

92 ProP concentrated at the cell poles in a CL-independent manner.

93 s nidulans, we show that AP-2 has a clathrin-independent essential role in polarity maintenance and g

94 lfment into a membrane vesicle by a clathrin-independent process.

95 course of evolution, a specialized clathrin-independent function necessary for fungal polar growth.

96 occus sanguinis, we have developed a cloning-independent methodology, which uses a counterselectable

97 rous pathogenic microorganisms by a cofactor-independent mutase (iPGM) structurally distinct from the

98 in hypoxic PH involves an early compartment-independent activation of lung macrophages toward a cons

99 this context, CD55 functions in a complement-independent manner and required lipid raft localization

100 increased titers of high-quality complement-independent antibodies with greater pre-F site O binding

101 Culture-independent bacterial community profiling confirmed that

102 Culture-independent diagnostics, the use of sepsis prediction sc

103 A dual approach, involving culture-independent and -dependent techniques, was used here to

104 We then compared these culture-independent genomes to existing genomes of bacterial iso

105 this has been challenging when using culture-independent high-throughput metagenomics.

106 ong G1 and G2/M cells, suggesting cell cycle-independent origin of cell-to-cell variation in Ccnb1 pr

107 Here we report a cell-cycle-independent developmental role for a master cell-cycle r

108 ver domain of the histidine kinase CYTOKININ-INDEPENDENT 1 (CKI1RD) from Arabidopsis thaliana We obse

109 Data-independent acquisition (DIA) is an emerging mass spectr

110 Data-independent acquisition mass spectrometry promises highe

111 Here, we present a data-independent acquisition (DIA) LC/MS-based approach, leve

112 on with chromatographic separation by a data-independent acquisition is a challenge in mass spectrome

113 id chromatography (LC) separation and a data-independent acquisition strategy for untargeted and low

114 ation with all-ion-fragmentation (AIF), data-independent-acquisition (DIA), and data-dependent-acquis

115 have developed a global ion library for data-independent acquisition approaches employing high-resolu

116 ciates with autosomes of germ cells in a DCC-independent manner to enrich H4K20me1 and trigger chromo

117 e damaged DNA after UV irradiation in a DDB2-independent manner.

118 intenance of genomic stability through a DDR-independent pathway.

119 ssorium repolarization involves a novel, DDR-independent S-phase checkpoint, triggered by appressoriu

120 n to contribute to antiviral immunity, death-independent roles for RIPK3 in host defense have not bee

121 cattering resulting in a "universal" density-independent (scaled) conductivity at high densities.

122 f anthocyanins, in a tissue- and development-independent manner.

123 essing (HER2-positive) breast cancer is dose-independent cardiac dysfunction.

124 as endophilin have been reported in dynamin-independent scission of tubular membrane necks, the cutt

125 bilization of Ctn RNA occurred in an editing-independent manner.

126 , suggesting that tDCS strengthened effector-independent representations.

127 These results are consistent with EIN3-independent developmental and transcriptional changes in

128 ommon endpoint of both EMT-dependent and EMT-independent cancer dissemination programs.

129 patients, generally leading to an endocrine-independent ER+ phenotype.

130 he estrogen receptor can promote an estrogen-independent phenotype that can be reverted by inhibiting

131 agonism is sufficient to drive growth-factor-independent growth in the context of concurrent tumor su

132 sealing, is involved in an early, Rho family-independent, actin stabilization that is integral to the

133 rom which we obtain a direct, magnetic-field-independent measurement of the hyperfine splitting.

134 rhamnolipids facilitate proton-motive force-independent tobramycin uptake, and 2-heptyl-4-hydroxyqui

135 comprises frequency-dependent and frequency-independent terms that reflect the proficiencies of the

136 aken together, the results suggest that FtsZ-independent structures of ZapA-ZapB provide additional p

137 identify novel factor(s) mediating HAdV-5 FX-independent entry, we investigated HAdV-5 transduction i

138 ) serum enhanced HAdV-5 transduction in a FX-independent manner in CHO-CAR and SKOV3-CAR cells (CHO o

139 endrites and spines through a specialized GA-independent trafficking network.

140 ble and particulate antigens in an IFN-gamma-independent manner.

141 , previous studies have reported that a gene-independent antiproliferative effect of Cas9-mediated DN

142 sion of the Cas9 endonuclease induces a gene-independent response that correlates with the number of

143 In addition, we introduce a novel genotype-independent test to detect methylation imbalance between

144 few are released by unconventional ER/Golgi-independent means.

145 he biological processes controlled by a GPCR-independent mechanism of G protein activation mediated b

146 tion (CCL2, CCL5), (v) may exert a granuloma-independent action that enables self-cure (CCL5), and (v

147 ndicating the potential importance of growth-independent metabolism for nutrient-limited mutualistic

148 Thus, growth-independent fermentation can conditionally stabilize or

149 lts demonstrate a lung-intrinsic, herniation-independent cause of PH in CDH.

150 human breast cancer cells, including hormone-independent and chemoresistant types.

151 tivator of transcription (STAT1), via an IFN-independent but EGFR- and integrin-dependent signaling p

152 findings identify HgIA as a novel type I IFN-independent model of systemic autoimmunity and implicate

153 efine a TRIF-dependent, TLR4- and type I IFN-independent pathway of sterile liver injury in which hep

154 (n=60) to specific anti-FcepsilonRI and IgE-independent fMLP stimulation was determined by basophil

155 lamellipodium buckles upward in a myosin II-independent manner.

156 rate marked differences in the acute insulin-independent effects by which leptin reverses fasting hyp

157 ent for type I diabetes providing an insulin-independent, normoglycemic state.

158 ion, leading to Baf60c induction and insulin-independent AKT activation.

159 ical approaches, we found that an interferon-independent mechanism involving Toll-IL-1-receptor domai

160 e determined the role of IFN-I-driven, ISGF3-independent signaling in regulating global gene expressi

161 Here we identify a kinase-independent function of class II phosphoinositide 3-OH k

162 ogenic Kras signalling and emergence of Kras-independent escaper populations (cells that acquire onco

163 anscriptomic and functional analyses of Kras-independent escapers reveal the presence of Smarcb1-Myc-

164 ha3 in TA cells that signals through an LATS-independent FAK/CDC42/PP1A cascade to control YAP-S397 p

165 tion of auxin gradients that override a LAZY-independent mechanism that creates an opposing gravity-i

166 that the 1st Hit is largely telomere length-independent, while the 2nd Hit is largely TL-dependent,

167 ient to sustain intrinsic signaling in a LIF-independent manner to promote ES cell pluripotency and s

168 R is necessary to enable Nanog to confer LIF-independent self-renewal, the mechanism of dimerization

169 Moreover, LIF-independent iOCT4 ES cells retain the capacity to differ

170 in and the tryptophan repeat can support LIF-independent colony formation.

171 ssion of OCT4 (iOCT4) supports long-term LIF-independent self-renewal of ES cells cultured in media c

172 P12 increase hepcidin expression in a ligand-independent manner, through BMP-SMAD signaling.

173 ate cancer through a noncanonical and ligand-independent pathway.

174 T-ALL NOTCH1 mutations result in ligand-independent and sustained NOTCH1-receptor signaling, whi

175 nd in beta-arrestin 2 recruitment, no ligand-independent activity could be measured.

176 osphorylation critically controls the ligand-independent endocytosis of GPR15.

177 Our results highlight an unexpected ligand-independent induction mechanism and suggest that constit

178 involved in nitrogen assimilation and light-independent chlorophyll synthesis are dramatically upreg

179 ght or shade, but are also affected by light-independent dark reversion.

180 onal study using a mutant defective in light-independent chlorophyll synthesis revealed that this pat

181 reveal the functional significance of light-independent chlorophyll synthesis in trophic growth.

182 for isotopic enrichments, with focus on mass-independent isotope effects due to symmetry, ignoring sm

183 a intermittent slips that exhibit a material-independent critical size distribution.

184 ly in a farnesylation-dependent but membrane-independent manner.

185 nificance of mitochondrial energy metabolism-independent signals in GIIS regulation; in particular, t

186 se metabolism-dependent pathways, metabolism-independent processes are suggested to also potentially

187 th DNA methylation-dependent and methylation-independent pathways.

188 Antibiotic treatment elicits microbiome-independent changes in local metabolites, but not those

189 ds, can bind to the same beta2-microglobulin-independent ligand as KIR2DS2.

190 responses, indicating a beta2-microglobulin-independent ligand for KIR2DS2.

191 G1 governs the miRNA-dependent and the miRNA-independent recruitment of AGO2 to lower the stability o

192 nic day 19) fetal rat hepatocytes is mitogen-independent and that mechanisms regulating mRNA translat

193 t Parkin affects mtDNA levels in a mitophagy-independent manner.SIGNIFICANCE STATEMENT Parkinson's di

194 in the analytical ultracentrifuge and model-independent SEDFIT-MSTAR analysis across a range of load

195 e other methods, scTDA is a nonlinear, model-independent, unsupervised statistical framework that can

196 tion from potassium and do not provide model-independent information about the spatial distribution o

197 These results offer a general, system/model-independent, physical/observable-based approach to ident

198 MP-7, beta-glucan-stimulated cells were mTOR-independent and used Dectin-1 receptor.

199 ning through Ragulator-dependent, but mTORC1-independent, modulation of BORC.

200 rated from oncogenic Hras, and even mutation-independent deformations to the tissue, can also be corr

201 sed by myosin-IIA overassembly, and a myosin-independent increase in microtubule acetylation, which i

202 We also found that NBR1-independent bulk autophagy prevents premature plant deat

203 This suggested a NEXT-independent Mtr4 function, and, consistent with this, we

204 ress on the roles of NFIC-dependent and NFIC-independent signaling pathways in tooth root formation.

205 entify an important Traf2-mediated, NFkappaB-independent, prosurvival pathway in the heart by suppres

206 egree of C-C bond equalization and a nucleus-independent chemical shift value lower than that of benz

207 DeltagpsB mutant was PgdA-dependent and OatA-independent.

208 fic enolase is an easily available, observer-independent prognostic biomarker.

209 Our findings demonstrate that Ras oncogene-independent activation of RALB signaling is a therapeuti

210 cell lines classified as K-Ras-dependent or -independent for co-dependency on protein kinase C delta

211 iable, and can be either light-dependent or -independent; the molecular origin of this difference is

212 rmally, supporting the idea of an osteoblast-independent mechanism for teleost vertebral centra forma

213 release may arise in part via NADPH oxidase-independent mechanisms.

214 ery, and consequently suppressing the oxygen-independent degradation of HIF-1alpha.

215 ivity is essential for p21-dependent and p21-independent mechanisms that radioprotect intestinal cryp

216 nction of NuMA in rDNA transcription and p53-independent nucleolar stress response supports a central

217 is needed in order to perform a critical p53-independent function and may obviate the need for genomi

218 We sought to identify p53-independent CCAR2 functions in SCC and to examine its ro

219 monstrate that NRF2 is a major target of p53-independent tumor suppression by ARF and also suggest th

220 s to recover from DNA stress and a rapid p53-independent ATR-Chk1-mediated apoptotic response.

221 ecific binding site can take place in a path-independent manner given reasonable values of the free e

222 Perfusion-independent regulation of epithelial pattern formation b

223 ases rather than on the cell surface acid pH-independent serine protease TMPRSS2, but Zhou et al. fou

224 We investigated glucose-6-phosphatase-independent endogenous glucose production in hepatocytes

225 molecule, and report protein kinase A (PKA)-independent CFTR activation by calmodulin.

226 varepsilon-dependent phosphorylation and PKC-independent, DAG-mediated membrane recruitment, possibly

227 activity on 3' overhangs, but this DNA-PKcs-independent endonuclease activity of Artemis awaited con

228 erminally truncated ARTEMIS showing DNA-PKcs-independent hairpin opening activity.

229 nd galactolipids) and implemented a platform-independent high-throughput-amenable analysis pipeline f

230 Pluripotency-independent conversion of endothelial cells into autolog

231 mutation- and single nucleotide polymorphism-independent method could be crucial in dominant diseases

232 Furthermore, RYBP is required for PRC1-independent recruitment of OCT4 to the promoter of Kdm2b

233 activation, both ligands activate G protein-independent ACKR3 responses and prompt arrestin recruitm

234 (n = 85), tracer sensitivity was largely PSA-independent.

235 egregate based on K-Ras dependency, as K-Ras-independent cells are more sensitive to topoisomerase in

236 ads to the development of several rare K-ras-independent forms of PC, with infrequent PDAC.

237 Notch-4/Int3 is ANK repeats dependent, Rbpj-independent, and is mediated by IKK activation and P50 p

238 ch-induced mammary tumor development is Rbpj-independent.

239 current (IA) through a cannabinoid receptor-independent mechanism mimicked by arachidonic acid, whic

240 ort a physiologically relevant NMDA-receptor-independent mechanism that drives increased AMPA recepto

241 that NHE9 regulates TfR-dependent, recycling-independent iron uptake in hBMVECs by fine-tuning the en

242 of subclinical primary aldosteronism (renin-independent aldosteronism) in normotension.

243 gate whether a spectrum of subclinical renin-independent aldosteronism that increases risk for hypert

244 through a novel pathway that is replication-independent, rapid, and locus-specific.

245 of quiescence, we confirmed the replication-independent mutational spectrum at the whole-genome leve

246 croptosis, in both RIPK1-dependent and RIPK1-independent manners.

247 te domain induced by TNFalpha leads to RIPK1-independent apoptosis when NF-kappaB activation is inhib

248 The interaction of CELF1 and RRP6 was RNA-independent and nucleus specific.

249 icated in both S-RNase-dependent and S-RNase-independent pollen rejection.

250 We investigated S-RNase-independent rejection of Solanum lycopersicum pollen by

251 stent subretinal fluid (SRF), but also a RPE-independent visual cycle for cone photopigment within th

252 olved in the control of another unknown RpoS-independent gene product(s) associated with borrelial re

253 go, showing that they are due to a secretion-independent function of Tango1.

254 the Detroit and St. Clair represent two semi-independent populations that could require separate mana

255 riptional SHAPE-Seq by developing a sequence-independent biotin-streptavidin (SAv) roadblocking strat

256 mosomal breakage regions suggests a sequence-independent mechanism for DNA breakage followed by telom

257 th a model where SFPQ*NONO promotes sequence-independent pairing of DNA substrates, albeit in a way t

258 impossible to explore the possible signaling-independent functions of the receptor, which are indicat

259 strate that the former loading leads to size-independent mechanical properties while the latter resul

260 -1/Prickle containing PCP pathway and a Slit-independent SAX-3/Robo pathway cooperate to regulate, vi

261 In vitro, we studied Smad-dependent and Smad-independent actions in isolated cardiac fibroblasts.

262 showing that TGFbeta induces TAZ via a Smad3-independent, p38- and MRTF-mediated and yet MRTF translo

263 endent constraint of proliferation and SMAD4-independent activation of apoptosis.

264 SMARCE1 drives invasion by forming a SWI/SNF-independent complex with the transcription factor ILF3.

265 Thus sortilin-dependent as well as sortilin-independent sorting mechanisms target aggregated Golgi m

266 y nuclear protein, which promotes starvation-independent, basal autophagy.

267 compared with lean liver to assess steatosis-independent effects.

268 Cell-cell fusion assays show a strain-independent failure of fusion pore enlargement among H2

269 us, oligolysine-PEG is a one-step, structure-independent approach that provides low-cost and effectiv

270 Next, we show that structure-independent processes, already present in bulk systems a

271 Biochemical assays show direct, substrate-independent compound binding to the Sirt6 catalytic core

272 elves to statistical analysis and are system-independent in that the effects of the system processing

273 nd demonstrate the importance of a BMAL1 TAD-independent mechanism for generating circadian rhythms i

274 system, regardless of task-dependent or task-independent states.

275 induced changes were TCF dependent, but TCF-independent TSSs exhibited the same hierarchy, indicatin

276 t OX40L/OX40 interaction is critical for TCR-independent selective proliferation of Foxp3(+) Tregs, b

277 Although PKC- is dispensable for TCR-independent Treg proliferation per se, it is essential f

278 ngthening of telomeres (ALT) is a telomerase-independent telomere maintenance mechanism that occurs i

279 This provides a model for 'temperature-independent' efficient TT formation and thermally activa

280 hape information, transduced through tension-independent mechanisms, can regulate phenotype.

281 er organisms revealed varying levels and TET-independent formation of this new RNA modification.

282 myelopoiesis through Tet2-dependent and Tet2-independent mechanisms.

283 In contrast, thymus-independent Ags generally do not induce germinal center

284 hquake frequency (e.g., time-dependent, time-independent, and clustered).

285 s then assigned an identity using a new time-independent machine-learning approach we call Neuron Reg

286 ction through a non-canonical, transcription-independent signalling mechanism that drives assembly of

287 ishes and demonstrates a novel transcription-independent GOF mutant p53-AMPK-FOXO3a-FOXM1 signaling c

288 s observations suggesting some transcription-independent (non-genomic) activity of auxin in cell elon

289 xes have opposing roles in the transcription-independent control of the actin cytoskeleton through th

290 ity likely underlie this form of translation-independent memory.

291 and MRTF-mediated and yet MRTF translocation-independent mechanism.

292 Activation is initiated in a Trem2-independent manner that involves downregulation of micro

293 n the airways in an IL-33-dependent but TRL4-independent manner.

294 est model was built using a set of cell type-independent features such as specific sequences recogniz

295 ull function, but can also signal in two ubi-independent modes, one dependent and one independent of

296 PIC requires an ATP-dependent, but unwinding-independent, activity of eIF4A.

297 Second, H. pylori also induces VacA-independent alteration of mitochondrial replication and

298 Q8 elicits antiangiogenic effects in a VEGF-independent in vitro model of angiogenesis and exerts an

299 -) definitive hematopoietic mesoderm and WNT-independent KDR(+)CD235a(+) primitive hematopoietic meso

300 Hsp20 binds AC9 in a Yotiao-independent manner and deletion of AC9 decreases Hsp20-a