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2 gulatory protein 2 ligase 1 (HOIL-1), HOIL-1-interacting protein, and SHANK-associated RH domain-inte
4 ion of Pk3 may involve Wilms tumor protein 1-interacting protein (Wtip), which physically associates
5 entary proteomic approaches to identify ACR4-interacting protein candidates that are likely regulator
6 l may facilitate the identification of APOL1-interacting molecules that could serve as new drug targe
7 ugh another negative immune regulator ARLPK1-interacting receptor-like kinase 1 (AKIK1), an active ki
8 om replication stress, and impairment in ATR-interacting protein (ATRIP) focus accumulation of SIRT2
10 east two-hybrid system to search for AtRALF1-interacting proteins in Arabidopsis, we identified calmo
12 reby prevents the BH3-only protein BIM (BCL2-interacting mediator of cell death)-dependent triggering
13 emerged as possibly the largest class of CaM-interacting proteins with undefined molecular functions
17 neurin B-like calcium sensors (CBLs) and CBL-interacting protein kinases (CIPKs) are involved in Al r
18 Calcineurin B-like proteins (CBLs) and CBL-interacting protein kinases (CIPKs) signal network have
20 421 residue is required for MCP1-induced CDK-interacting protein 1 (p21Cip1) nuclear export and degra
23 binds epilepsy-associated potassium channel-interacting proteins including KCNAB2 and KCNIP1, and in
24 nd further investigated ENKUR, a TRP channel-interacting protein identified in the cilia of all three
27 nd mental retardation-type 3) as a chromatin-interacting protein that promotes DNA repair by homologo
28 cation of the entire repertoire of chromatin-interacting RNAs and their respective binding sites.
31 st 50 proteins, including clathrin, clathrin-interacting proteins, actin filaments, and actin binding
32 new data on the biological function of a CML-interacting partner, PRR2 (PSEUDO-RESPONSE REGULATOR 2),
36 ble-click stapled peptides encoding the Ctf4-interacting peptide (CIP) of the replicative helicase su
41 interaction with SHANK-associated RH domain-interacting protein was impaired in a male fetus with IP
43 udes the MyoA light chain myosin tail domain-interacting protein (MTIP) and several glideosome-associ
44 ctor 1 (RIF1) and Pax transactivation domain-interacting protein (PTIP), in the past few years to elu
45 -containing PTIP (Pax transactivation domain-interacting protein) chromatin regulator is controlled b
49 hese data show how a deubiquitinating enzyme-interacting protein dictates the efficiency and specific
51 ively regulates TGF-beta signaling via ERBB2-interacting protein (ERBIN), a SMAD anchor for receptor
52 guish these functions for FIP200 (FAK family-interacting protein of 200 kDa), an Atg in autophagy ind
54 n of FUBP1 and antagonize the binding of FBP-interacting repressor to FUBP1, thereby coordinating the
55 cterized protein named cardiac-enriched FHL2-interacting protein (CEFIP), which exhibited a heart- an
56 defense responses and interacts with FIN219-interacting protein 1 (FIP1) under FR light conditions.
58 led with mass spectrometry, identified FOXC1-interacting proteins including a group of heterogeneous
59 (FRQ), casein kinase 1a (CK1a), and the FRQ-interacting RNA Helicase (FRH) rhythmically represses ge
60 trength of FvTox1 with four different FvTox1-interacting peptides and experimentally confirmed the si
63 This mobility increase is dependent on Gag-interacting Env tail but not on changes in viral envelop
67 pendent manner, and tumors bearing a non-GNA-interacting C668S-EZH2 mutation exhibited resistance to
69 st, Galphai1(Q204L) did not reverse Rap1-GTP-interacting adaptor molecule (RIAM)-dependent increases
70 sent a clear proof of principle that MT-Hec1-interacting compounds may represent novel powerful antic
71 onic hedgehog (Shh)-binding loop of hedgehog-interacting protein (HHIP) and subjected to multiple rou
76 e show that CHIP (carboxyl terminus of Hsc70-interacting protein), a U-box E3 ligase, suppresses tumo
78 mammalian ubiquitin ligase C-terminal Hsp70-interacting protein (CHIP), if freed from chaperones dur
79 and SNX1) that increase and four (huntingtin-interacting protein 1 [HIP1], HIP14, GASP-1, and Nedd4)
81 ed the interactions between the isolated INT-interacting MVP domains (iMVP) and wild-type INT and com
82 and neurotransmitter release, as a novel IRP-interacting transcript, and studied its role in iron met
83 Furthermore, we identified potential JMJD8-interacting proteins that are known to regulate protein
84 tivated by these problems, we identified JNK-interacting protein 3 (JIP3) as an important regulator o
85 ulation of the axonal transport proteins JNK-interacting protein 1 and amyloid beta precursor protein
86 show that in mature tissues TMV 126/183-kDa-interacting Aux/IAAs predominantly express and accumulat
87 tophagy regulator BCL2/adenovirus E1B 19-kDa-interacting protein 3-like (BNIP3L, best known as NIX) a
88 eracting serine-threonine kinases MAP kinase-interacting kinase 1 (Mnk1/2), the eIF4E upstream kinase
90 nhibitor of mitogen-activated protein kinase-interacting serine-threonine kinases MAP kinase-interact
92 The family member in kinetoplastids, KKT-interacting protein 1 (KKIP1), associates with the kinet
93 inction is mirrored in the phylogeny of KNOX-interacting BELL proteins, in that a gene duplication oc
95 nation of the arginine residue within an LC3-interacting region motif of immunodominant MOG peptides
98 X1BP1 binding of LC3 and GABARAP via its LC3-interacting region (LIR), but not its ubiquitin-binding
99 ate peptides that possess bona fide LIR (LC3-interacting region) properties and are selective for ind
100 y of the serine 34/35-phosphorylated Nix LC3-interacting region (LIR) to LC3B and formation of a very
101 To this end, we showed that removing the LC3-interacting region of p62, which facilitates p62-mediate
106 Our approach identified 127 potential MALAT1-interacting proteins and established a highly connected
107 the signaling axis involving p38 MAPK, MAPK-interacting kinase (MNK), and eukaryotic translation ini
111 ications introduced directly in the membrane-interacting loops and/or by modifying residues away from
112 ld form, likely in combination with membrane-interacting ACT segments, a proteolipidic toroidal pore
117 k-1 associated with FKBP12, an abundant mTOR-interacting protein, enabling accumulation of RapaLink-1
119 ANCE STATEMENT The deletion of the Miz1 (Myc-interacting zinc finger protein 1) POZ (POxvirus and Zin
120 domain of the transcription factor Miz1 (Myc-interacting zinc finger protein; encoded by Zbtb17) in m
122 kinases consisting of MAP4K4, Traf2- and Nck-interacting kinase (TNIK or MAP4K7), and misshapen-like
123 1 (MINK1 or MAP4K6) and TNIK Traf2- and Nck-interacting kinase (TNIK or MAP4K7), as upstream regulat
124 amily member 21 (IgSF21) as a neurexin2alpha-interacting membrane protein that selectively induces in
125 f a peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) to p53-RS, but not the p53 form wit
126 Ocean were dominated by low coercivity, non-interacting, single-domain (SD) magnetite particles, whe
129 system, the coupling occurs via a second non-interacting qubit, initially quantum correlated with the
131 othermal magnetisation behavior from the non-interacting case, indicating weak dipolar interactions.
132 that the effective dimensionality of the non-interacting lattice component can evolve from quasi-3D t
135 ion temperature of 135 degrees C, as the non-interacting vesicles are converted into weakly interacti
137 es are typically designed to replace two non-interacting residues with a constraining, olefinic stapl
140 entified competitive and noncompetitive OCT1-interacting ligands in a library of 1780 prescription dr
142 cently, a new RBP-J (mammalian CSL ortholog)-interacting protein termed RITA has been identified and
143 nt binding protein (CBP), p300, and Cbp/p300-interacting transactivator 2 (Cited2) was increased in t
145 on is mediated by the newly identified PALB2-interacting domain (PID) in RNF168 and the WD40 domain i
146 that AcrIIA4 competitively occupies both PAM-interacting and non-target DNA strand cleavage catalytic
153 lation of WD repeat domain, phosphoinositide-interacting protein 2 in B cells alone enhanced this non
154 ) mutant, which lacks one of the phototropin-interacting CPT proteins, shows reduced sensitivity to b
156 sion of the transcription factor PHYTOCHROME-INTERACTING FACTOR (PIF4) may contribute to hybrid vigor
157 by the bHLH transcription factor PHYTOCHROME-INTERACTING FACTOR 4 (PIF4) [6-8], and enhanced stabilit
158 negatively acting factors (e.g. phytochrome-interacting factors or PIFs) are degraded in response to
160 by mediating the degradation of phytochrome-interacting transcription factors (PIFs) through the N-t
162 an be induced by CK and that the phytochrome-interacting factor 4 (PIF4) is required for this upregul
169 the histone ubiquitin ligase RNF8 in a Piwi-interacting RNA (piRNA)-independent manner, and MIWI sta
170 -directed gene silencing, we employed a Piwi-interacting RNA (piRNA)-targeted reporter assay in Droso
173 e conserved Piwi family of proteins and piwi-interacting RNAs (piRNAs) have a central role in genomic
177 echanism of biogenesis for tRNA-derived Piwi-interacting RNAs (td-piRNAs) expressed in Bombyx BmN4 ce
178 ere we show that PNLDC1 is required for piwi-interacting RNA biogenesis, transposon silencing, and sp
181 se results define PNLDC1 as a mammalian piwi-interacting RNA biogenesis factor that protects the germ
182 our current understandings of mammalian PIWI-interacting RNAs (piRNAs) and their role in TE regulatio
185 f sncRNAs including microRNAs (miRNAs), Piwi-interacting (piRNAs), small nuclear, nucleolar, cytoplas
191 e, we showed that tsRNAs are similar to Piwi-interacting RNAs (piRNAs) and demonstrated that ts-101 a
192 As requires a critical step of trimming piwi-interacting RNA intermediates to achieve optimally sized
193 ng and causes accumulation of untrimmed piwi-interacting RNA intermediates with 3' end extension, lea
194 ein phosphatase 1 (PP1c) is dictated by PP1c-interacting proteins, here we sought to identify new PP1
195 and quantify several weakly bound proteasome-interacting proteins and examine their roles in stress-m
196 adapter protein Ecm29 is the main proteasome-interacting protein responsible for stress-triggered rem
197 ng BNIP3 (BCL2/adenovirus E1B 19-kDa protein-interacting protein 3) and GLUT1 (glucose transporter 1)
200 t and activation of Munc13-1 depends on Rab3-interacting proteins (RIMs), we demonstrate here that bM
202 icle exocytosis.SIGNIFICANCE STATEMENT RAB3A-interacting molecules 1 and 2 (RIM1/2) are essential reg
203 it tetratricopeptide repeat-containing Rab8b-interacting protein (TRIP8b) also produces antidepressan
204 5, tetratricopeptide repeat-containing Rab8b-interacting protein (TRIP8b), binds to and functions as
206 e show that the HPV E2 protein targets Rad50-interacting protein 1 (Rint1) to facilitate virus genome
207 inactivation of its ATP-binding site, RAD51-interacting domain, or phosphorylation site causes exces
209 (ATM) phosphorylates 53BP1 and recruits RAP1-interacting factor 1 (RIF1) to dissociate the 53BP1-TIRR
214 , TNF receptor-associated factor 2, receptor-interacting protein 1, Hemo-oxidized iron regulatory pro
215 h, we demonstrate the presence of a receptor-interacting protein kinase 3 (RIPK3)-mixed lineage kinas
216 lex interplay between caspase-8 and receptor-interacting protein (RIP) kinase RIP 3 (RIPK3) driving e
217 for left-handed helix (Z-form) and receptor-interacting protein homotypic interaction motif (RHIM) d
218 iated via death domain (TRADD), and receptor-interacting serine/threonine protein kinase 1 (RIPK1).
219 h as CD141, GATA3, OX40 ligand, and receptor-interacting serine/threonine-protein kinase 4 (RIPK4), w
221 in the absence of NOD proteins, but receptor-interacting protein 2 is not involved in CD8 single-posi
223 tic form of cell death initiated by receptor-interacting protein kinase-3 (RIPK3) and mixed lineage k
224 cell suicide mechanism initiated by receptor-interacting protein kinase-3 (RIPK3) phosphorylation of
225 mixed lineage kinase-like (MLKL) by receptor-interacting protein kinase-3 (RIPK3) results in plasma m
227 gulatory factors (DAI) that contain receptor-interacting protein (RIP) homotypic interaction motifs (
228 receptor gamma (RARgamma) controls receptor-interacting protein kinase 1 (RIP1)-initiated cell death
231 blasts induced NOD2, the downstream receptor-interacting serine/threonine-protein kinase 2 (RIPK2), r
234 e itself or AIPL1 (aryl hydrocarbon receptor-interacting protein-like 1), leads to retinal diseases c
235 terferon (IFN-I) response to induce receptor-interacting protein (RIP) kinase-mediated necroptosis in
236 ubiquitin-editing complex inhibits receptor-interacting Ser/Thr kinase (RIPK) activation by removing
238 ession of the necroptosis mediators receptor-interacting protein kinase 3 (RIPK3) and mixed lineage d
239 re, disruption of the LXXLL nuclear receptor-interacting motif present in ACTN4 results in reduced GR
240 sis requires the kinase activity of receptor-interacting protein kinase 1 (RIPK1), a key regulator of
242 ll death that critically depends on receptor-interacting serine-threonine kinase 3 (RIPK3) and mixed
243 s-associated death domain (FADD) or receptor-interacting protein kinase 1 (RIP1) cell death regulator
244 tically, Traf2 critically regulates receptor-interacting proteins 1 and 3 and mixed lineage kinase do
245 threonine-protein kinase 1 (RIPK1), receptor-interacting serine/threonine-protein kinase 3 (RIPK3), T
246 ent, PKP1 (plakophilin-1) by RIPK4 (receptor-interacting serine-threonine kinase 4) during epidermal
248 phil extracellular traps (NETs) via receptor-interacting protein kinase (RIPK) 1/3- and mixed-lineage
249 QP2) and the lysosomal trafficking regulator-interacting protein LIP5 targets AQP2 to multivesicular
251 tion site required the highly conserved Rev1-interacting region (RIR) motif in XRCC1 and included thr
252 ike Homologous protein 5 (PfRH5) and the RH5-interacting protein (PfRipr), essential for erythrocyte
253 ssense mutations in CIT, encoding citron rho-interacting kinase (CIT), which has established roles in
255 mutations in CIT, encoding CRIK (citron rho-interacting kinase)-a component of the central spindle m
258 sis downregulated the abundance of RNA5SP141-interacting proteins, which allowed RNA5SP141 to bind RI
259 , our results implicate INPP5E, a novel RPGR-interacting protein, in the pathogenesis of RPGR-associa
261 y of 89 pyrenoid proteins, including Rubisco-interacting proteins, photosystem I assembly factor cand
262 In fact, based on experiments using the self-interacting FM domain, it appears generally true that ag
268 acterization of a mouse mutation in striatin-interacting protein 1 (Strip1) that disrupts migration o
269 the biochemically defined mammalian striatin-interacting phosphatases and kinase (STRIPAK) complexes
270 r with other core components of the striatin-interacting phosphatase and kinase (STRIPAK) complex, we
271 of the STUbL SLX5 or disruption of its SUMO-interacting motifs, confirming that Tof2 is targeted for
274 r 1 (IF1) is a nuclear-encoded, ATP synthase-interacting protein that selectively inhibits the hydrol
275 dentified DDX5, FUS, EWSR1 and LSM14A as TAD-interacting proteins sensitive to F32L and/or Y96L mutat
276 TEL2 (Telomere maintenance 2) and TTI1 (Tel2-interacting protein 1), to form the triple T complex tha
279 RT as well as other telomerase- and telomere-interacting proteins have provided insights into telomer
280 trate here that transcription factor COUP-TF-interacting protein 1 (CTIP1/BCL11A; hereafter CTIP1) is
281 Since we recently identified thioredoxin-interacting protein (TXNIP) as an upstream regulator of
282 mediated by the de-repression of thioredoxin-interacting protein, a major redox control molecule, and
288 sential for Thr9 phosphorylation of the TRAF-interacting protein TIFA, triggering activation of the N
289 n genes encoding the shelterin proteins TRF1-interacting nuclear factor 2 (TIN2) and adrenocortical d
290 n, and reduced recruitment of a known TRP120-interacting host protein, PCGF5, to ehrlichial inclusion
292 al extremity of Galphas contains a ubiquitin-interacting motif (UIM), a sorting element usually found
293 ia an amino acid sequence, known as the UFM1-interacting sequence (UIS), located outside the adenylat
294 eover, depletion of DHX38, encoding an USP39-interacting splicing factor, also reduces the viability
298 elegans AMPylation enzymes-huntingtin yeast-interacting protein E (HYPE) and filamentation-induced b
299 Tubule formation depends on the Rab7/Ypt7-interacting retromer complex, consisting of the sorting
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