ライフサイエンスコーパス: -lead

1 up substitutions on the quinone ring at R(1)-lead to significant impacts on the Michaelis constant (K

2 During in-vivo swine studies (n = 6), 12-lead ECG signals were recorded at baseline and following

3 As a first step, participants recorded a 12-lead ECG and reported their relevant medical history.

4 3 flow) but persistent ST elevation on a 12-lead ECG are at high risk for subsequent death and left

5 Q waves on a 12-lead ECG are markers of a prior myocardial infarction (M

6 T-wave axis, polarity, and amplitude on a 12-lead ECG during sinus rhythm were compared between CM an

7 Screening advocates have recommended a 12-lead ECG for the early detection of HCM in athletes, yet

8 The fQRS on a 12-lead ECG is a marker of a prior MI, defined by regional

9 T-wave inversion on a 12-lead ECG is usually dismissed in young people as normal

10 ace-mapping at these sites can generate a 12-lead ECG morphological match to a targeted ventricular t

11 V(3) is a relatively common finding in a 12-lead ECG of children and adolescents and is infrequently

12 mm.s is a relatively common finding in a 12-lead ECG of middle-aged subjects.

13 The mean spatial resolution of a 12-lead ECG pace map for the VT exit site was 2.9 +/- 4.0 c

14 A 12-lead ECG was monitored continuously, and repolarization

15 volt T-wave alternans exercise test and a 12-lead ECG.

16 ed value and controversies of including a 12-lead electrocardiogram (ECG) in addition to a comprehens

17 A 12-lead electrocardiogram (ECG) was obtained at these times

18 with baseline heart rate documented by a 12-lead electrocardiogram without pacing or atrial fibrilla

19 A 12-lead electrocardiogram, 3 min rhythm strip, and blood sa

20 Patients had a 12-lead Holter monitor to assess the presence of effective

21 rance test, overnight urine collection, a 12-lead resting electrocardiogram, measurement of carotid i

22 We developed a 12-lead smartphone-based electrocardiogram (ECG) acquisitio

23 learances and CVD evaluations including a 12-lead surface electrocardiogram, an echocardiogram, and c

24 ects underwent electrocardiography with a 12-lead surface, in which, along with several other indexes

25 We screened all 12-lead ECGs over 6 months at 2 large hospital systems and

26 Original analog 12-lead ECG signals can be reconstructed from digital data

27 We analysed 12-lead ECGs from 45 haemodialysis and 12 LQT2 patients.

28 We analyzed 12-lead ECGs of 401 first-degree relatives of individuals w

29 CG) monitoring during hospitalization and 12-lead ECG was performed daily until hospital discharge.

30 questionnaire, physical examination, and 12-lead ECG.

31 ants completed both baseline 5-minute and 12-lead electrocardiogram recordings on a nondialysis day.

32 vital signs, a physical examination, and 12-lead electrocardiograph.

33 exposure, blood pressure, heart rate, and 12-lead electrocardiography were monitored throughout the 2

34 M, we studied, using echocardiography and 12-lead electrocardiography, the phenotypic expression caus

35 ts, with incident AF, diagnosed by annual 12-lead ECGs and hospital discharge records, from 1989 to 2

36 To limit radiofrequency applications, 12-lead ECG during VT and pacemapping guided placement of l

37 The corrected baseline 12-lead ECG QT interval duration (QTcorr) was determined by

38 dy stratified by QRS duration on baseline 12-lead ECG.

39 Baseline 12-lead ECGs were evaluated with regard to QRS morphology.

40 tal of 93 patients had AF on the baseline 12-lead electrocardiogram (ECG).

41 nary artery was induced and documented by 12-lead ECG and coronary angiography.

42 rty-four family members were evaluated by 12-lead ECG, echocardiogram, 24-hour Holter monitoring, and

43 er when AF recurrence was not captured by 12-lead ECG.

44 We also evaluated AF recurrence by 12-lead electrocardiogram (ECG) at 3, 6, and 12 months.

45 ixty-six family members were evaluated by 12-lead electrocardiogram (ECG), echocardiogram, and labora

46 Continuous 12-lead ECG monitoring can be an inexpensive and reliable m

47 d by ST-segment analysis using continuous 12-lead electrocardiography.

48 the INTEGRITI trial with 24-h continuous 12-lead ST-segment monitoring and angiography at 60 min.

49 Compared to conventional 12-lead ECG, more detailed ECG lead configurations may prov

50 Conventional 12-lead electrocardiogram, a widely used noninvasive tool i

51 Clinical data, 12-lead ECG, 12-hour Holter recordings, coronary angiograph

52 ed life support should include diagnostic 12-lead electrocardiography programs as one of their servic

53 ion (WISE) study who had complete digital 12-lead ECG and quantitative angiography data were studied.

54 RSp measured from high-resolution digital 12-lead ECGs independently predicts ventricular tachyarrhyt

55 High-resolution (1024 Hz) digital 12-lead ECGs were recorded during intrinsic rhythm.

56 mpared original and post-DAC re-digitized 12-lead ECG data files ( approximately 5-minutes long) in t

57 Using digitized 12-lead ECGs from 553 normal adults (426 males) with HRs co

58 ed symptom-limited cycle ergometry during 12-lead ECG monitoring.

59 ultaneously monitored with a 10-electrode/12-lead electrocardiogram obtained every 2 mins (criterion

60 We evaluated 12-lead ECGs of 10 899 Finnish middle-aged subjects (52% me

61 were evaluated with history, examination, 12-lead ECG, and further investigations as appropriate.

62 We examined 12-lead electrocardiograms before surgery, immediately afte

63 se of this study was to validate existing 12-lead electrocardiographic (ECG) ST-segment elevation myo

64 GMs usually are an accurate surrogate for 12-lead ECGs for differentiating clinical VTs from other VT

65 eases (eg, HCM) such as consideration for 12-lead electrocardiograms.

66 yocardial ischemia compared with frequent 12-lead electrocardiograms.

67 Baseline QRSd was obtained from 12-lead ECGs before pacemaker implantation in MOST, a 2010-

68 Baseline QRSd from 12-lead ECGs before pacemaker implantation were analyzed in

69 ere measured at baseline (1987-1989) from 12-lead ECGs.

70 and their dispersions were measured from 12-lead electrocardiogram.

71 All had 12-lead electrocardiogram recordings available for cardiac

72 can be facilitated by use of pre-hospital 12-lead electrocardiography (P12ECG).

73 Body-surface QRST integrals and QTd in 12-lead ECG and 64-lead body-surface potential maps were ev

74 Standard evaluation included 12-lead ECG and at least 1 dedicated non-CMR cardiac study

75 al changes ("athlete's heart"), including 12-lead ECG alterations.

76 econd opinions for difficult-to-interpret 12-lead ECGs, either locally or remotely through the use of

77 ansplantation must include an interpreted 12-lead electrocardiogram (ECG).

78 angiography was performed at 90 minutes, 12-lead ECGs were obtained at baseline, 90, and 180 minutes

79 ed using VMHDVCG extracted from intra-MRI 12-lead ECGs, providing a means to enhance patient monitori

80 an be used to validate existing and novel 12-lead ECG criteria.

81 og conversion (DAC) and reconstruction of 12-lead ECGs.

82 to objectively quantify the similarity of 12-lead electrocardiogram (ECG) waveforms using two quantit

83 Inclusion of 12-lead electrocardiography (ECG) in preparticipation scree

84 fore participating in sports, the role of 12-lead electrocardiography (ECG) remains uncertain.

85 1 of a 2-part series on interpretation of 12-lead resting electrocardiograms (ECGs).

86 for at least 15 minutes and confirmed on 12-lead ECG and occurring within the first postoperative we

87 acterized as right-sided or left-sided on 12-lead ECG recordings at baseline and during isoproterenol

88 Those with sinus rhythm on 12-lead ECG, no history of AF, and >/=2 risk factors accord

89 The QT intervals were measured on 12-lead ECG.

90 nalysis, orthostatic vital signs, WSF, or 12-lead ECG parameters.

91 ischarge records or death certificates or 12-lead ECGs performed during 3 triennial follow-up visits.

92 novel panel consisting of pulse oximetry, 12-lead electrocardiography, and serum troponin T would hav

93 cardial infarction diagnosed on paramedic 12-lead ECG.

94 oximately 16 h predose to 24 h postdose); 12-lead electrocardiograms (ECGs); clinical chemistry, hema

95 independently reviewed all postoperative 12-lead electrocardiograms.

96 ion, including Rose angina questionnaire, 12-lead electrocardiography, C-reactive protein, and calcul

97 0 (1%) among 848 individuals who recorded 12-lead ECG.

98 ight was directly measured, and a resting 12-lead ECG obtained under standardized conditions.

99 ent for bedside interpretation of resting 12-lead ECGs in routine and emergency situations.

100 Limited studies have assessed the resting 12-lead electrocardiogram (ECG) as a screening test in inte

101 istory, physical examination, and resting 12-lead electrocardiogram (ECG) with a 30-second lead II rh

102 r suggested by abnormalities on a resting 12-lead electrocardiogram (ECG).

103 Half the cohort (26/52) had resting 12-lead electrocardiogram abnormalities: 25/26 had repolari

104 ans younger than 56 years who had resting 12-lead electrocardiography, 90.5% of whom were men.

105 ragmented QRS (fQRS) complex on a routine 12-lead ECG is another marker of depolarization abnormality

106 iogram with ST segment trends and routine 12-lead electrocardiogram) and clinical assessment for dete

107 7 years; 54% women) who underwent routine 12-lead electrocardiography.

108 n of data collected on one manufacturer's 12-lead ECG hardware/software into that of any other.

109 ters were determined from a baseline 10-s 12-lead ECG.

110 Serial 12-lead electrocardiograms were recorded at steady state du

111 Several 12-lead ECG parameters, such as the QRS-T angle and the QRS

112 nces, physical examinations, vital signs, 12-lead electrocardiogram, and laboratory safety.

113 ess network that facilitates simultaneous 12-lead ECG transmission from emergency medical services (E

114 acement of the electrodes in the standard 12-lead and a more detailed 64-lead ECG configuration were

115 n on atrial activation using the standard 12-lead ECG alone.

116 ats through leads II and V4 on a standard 12-lead ECG and corrected by using the Bazett formula.

117 ive clinical characteristics and standard 12-lead ECG data were examined.

118 Higher prevalence of ER in a standard 12-lead ECG in victims of SCD than in survivors of an acute

119 val, as measured by the resting, standard 12-lead ECG, reflects the duration of atrial/atrioventricul

120 mplexity parameters derived from standard 12-lead ECGs for AF termination and long-term success of ca

121 s TPE were measured from digital standard 12-lead ECGs in 5618 adults (46% men; mean age 50.9+/-12.5

122 ll voltage criteria derived from standard 12-lead ECGs recorded at baseline and biannually were compa

123 ngle can be easily obtained from standard 12-lead ECGs, but its predictive ability is not established

124 nd SVG azimuth) were measured on standard 12-lead ECGs.

125 The standard 12-lead electrocardiogram (ECG) provides a method for non-i

126 referred for cardiac evaluation (standard 12-lead electrocardiogram and transthoracic echocardiograph

127 arameters were measured from the standard 12-lead electrocardiogram.

128 QT interval was measured using a standard 12-lead electrocardiogram.

129 The MAD score can be used to standardize 12-lead ECG waveform morphology comparisons among different

130 l assessments, echocardiographic studies, 12-lead electrocardiograms, 24-hour Holter monitoring, bloo

131 sessment of atrial dimensions and surface 12-lead ECG measurement of the P-wave duration and its disp

132 tion or size between patients meeting the 12-lead ACC/ESC ST-segment elevation criteria and those onl

133 The only useful diagnostic tests were the 12-lead and exercise electrocardiograms and ajmaline provoc

134 cific ECG conduction abnormalities on the 12-lead ECG at study entry with occurrence of VT/VF in 431

135 Tu and RTu dispersion determined from the 12-lead ECG did not consistently reflect the myocardial cha

136 Comparison of the 12-lead ECG morphology between ventricular tachycardia (VT)

137 The 12-lead ECG waveforms of the clinical tachycardia and pace-

138 ratio >1 in lead V1 is difficult with the 12-lead ECG, especially in patients with prior apical infar

139 cted in temporal indices derived from the 12-lead ECG, they can be readily identified with high-resol

140 onclusive scalar waveform analysis of the 12-lead ECG.

141 VT exit site was determined for both the 12-lead ECGs and the ICD EGMs using a customized MATLAB pro

142 The 12-lead ECGs are interpreted via telemedicine.

143 The 12-lead ECGs of the clinical VTs were compared with 64 diff

144 f infrequently measured parameters of the 12-lead electrocardiogram (ECG) in predicting cardiovascula

145 nce endpoint, biventricular pacing on the 12-lead electrocardiogram at 1 month, was achieved in 33 of

146 In 18 patients, the 12-lead electrocardiographic morphology was left bundle bra

147 ion was not consistently reflected in the 12-lead or 64-lead ECG QTd or in the body-surface QRST inte

148 T wave quantitative analysis on the 12-lead surface ECG provides an effective, novel tool to di

149 These patients were identified through 12-lead ECGs obtained during routine visits at week 2, mont

150 cene </=10 minutes, ambulance on scene to 12-lead ECG acquisition </=8 minutes, on-scene time </=15 m

151 The subjects underwent 12-lead electrocardiography and two-dimensional echocardiog

152 he incidence of ineffective capture using 12-lead Holter monitoring and to assess whether this affect

153 ight ventricular outflow tract (RVOT) VT, 12-lead ECG pace-maps were acquired from three superior sep

154 d 532 survivors of such an event, in whom 12-lead ECGs recorded before and unrelated to the event cou

155 Screening young athletes with 12-lead ECG plus cardiovascular-focused history and physica

156 Clinical VT had been documented with 12-lead ECGs in 15 of 21 patients.

157 linical VT was defined by comparison with 12-lead electrocardiograms and stored implantable cardiover

158 ected by pre-participation screening with 12-lead electrocardiograms.

159 ial catheter mapping and ablation of VT, 120-lead body surface potential mappings were obtained durin

160 eractions with site I-zanamivir and BCX 2798-lead to the activation of site II.

161 picardial, body surface, precordial, and a 6-lead optimal set.

162 essments included orthostatic vital signs; 6-lead continuous telemetry monitoring (approximately 16 h

163 study was directed at developing spatial 62-lead electrocardiogram (ECG) criteria for classification

164 The 62-lead ECG of CCW and CW typical atrial Fl in man is chara

165 btain the location of the stimulus from a 64-lead ECG system was developed.

166 the morphology of the ECG signals from a 64-lead vest and the location of the origin of rapid atrial

167 the ECG signals in multiple leads (e.g. a 64-lead vest) may provide a viable approach.

168 QRST integrals and QTd in 12-lead ECG and 64-lead body-surface potential maps were evaluated for thei

169 the standard 12-lead and a more detailed 64-lead ECG configuration were selected.

170 consistently reflected in the 12-lead or 64-lead ECG QTd or in the body-surface QRST integral maps.

171 From 4 other anesthetized pigs, 64-lead body surface potential maps were recorded during si

172 bserved experimentally (obtained from the 64-lead ECG system), showing a strong agreement between the

173 Using 64-lead EEG recorded from human subjects receiving computer

174 In 14 patients with a history of AF, 67-lead body surface recordings were simultaneously registe

175 lten salt electrolyte, and a liquid antimony-lead alloy positive electrode, which self-segregate by d

176 Here we describe a lithium-antimony-lead liquid metal battery that potentially meets the per

177 , ventricle (3), or both chambers (4; atrial-lead threshold, 4.7+/-4.3 versus 0.7+/-0.3 V; ventricula

178 ffects, with trials proceeded by an auditory-lead needing more auditory-lead to seem simultaneous, an

179 ed by an auditory-lead needing more auditory-lead to seem simultaneous, and vice versa.

180 rony over a wide range, from 512 ms auditory-lead to 512 ms auditory-lag, and judged whether they see

181 llead compounds generated by a halogen-boron-lead exchange sequence.

182 Ms) is a rapidly developing approach in drug-lead discovery.

183 investigate the safety and efficacy of dual-lead thalamic DBS (one targeting the ventralis intermedi

184 fied and the time periods that are examined--lead to differences in interpretation of study results.

185 paramagnet under an external magnetic field)-lead to three kinds of thermoelectromagnetic effect: cha

186 -Hutchinson Gilford Progeria Syndrome (HGPS)-lead to reduced ITL formation and telomere loss.

187 itro and in vivo analyses of HTS-derived hit-lead compounds, we identified a novel anticancer compoun

188 knowledge and hence--directly or indirectly--lead to improvements in the treatment and prevention of

189 ractions (phosphate-in-pocket interactions)--lead to higher G/U conservation than others.

190 We use marginal linear models and lag-lead analysis to measure ecological associations between

191 ages that were previously determined by lead-lead dating of CAIs, which may be overestimated by sever

192 itic materials using the high-precision lead-lead (Pb-Pb) chronometer.

193 is a cornerstone of the high-precision lead-lead dates that define the absolute age of the solar sys

194 We prospectively studied manganese-lead interactions in early childhood to examine whether

195 early childhood to examine whether manganese-lead coexposure is associated with neurodevelopmental de

196 We find that the molecule-lead coupling, electron transfer, and conductance all de

197 approach allows its application to any multi-lead ECG system.

198 ved a general approach relevant to any multi-lead ECG system.

199 We use the strontium-neodymium-lead isotopic composition of proglacial sediment dischar

200 highly piezoelectric lead magnesium niobate-lead titanate (PMN-PT) layer 8mum in thickness thinly co

201 We found the use of non-lead ammunition significantly reduced lead exposure in e

202 agnostics and clinical data as an LSE or non-lead system event by 2 physicians after reviewing the el

203 009 and 2010 hunting seasons we provided non-lead rifle ammunition to local hunters and recorded that

204 The non-lead system event detection rate was different among lea

205 t 24% and 31% of successful hunters used non-lead ammunition, respectively.

206 posed to lead, and the efficacy of using non-lead rifle ammunition to reduce lead in eagles.

207 were LSEs (including 65 LFs) and 95 were non-lead system events.

208 starting in the morning with ambulatory one-lead ECG monitors.

209 Organo-lead halide perovskite solar cells have emerged as one o

210 Organo-lead halide perovskite solar cells have gained enormous

211 We report on a class of platinum-lead/platinum (PtPb/Pt) core/shell nanoplate catalysts t

212 permanent RV IHM system similar to a single-lead pacemaker.

213 moderately symptomatic heart failure, single-lead ICD therapy was not associated with any detectable

214 Prophylactic use of single-lead, shock-only ICD therapy is economically attractive

215 onservatively programmed, shock-only, single-lead ICD (829 patients).

216 o placebo, amiodarone, or shock-only, single-lead ICD therapy.

217 1:1) to receive 3 months of optimised single-lead DBS-either VIM or VO.

218 e available, historical and prolonged single-lead electrocardiogram recordings during electrocardiogr

219 Screening with twice-weekly single-lead iECG with remote interpretation in ambulatory patie

220 favorable effect on survival, whereas single-lead, shock-only ICD therapy reduces overall mortality b

221 failure patients in SCD-HeFT in whom single-lead ICD therapy was of no benefit and other subsets in

222 sult could be further evidence of a southern-lead North-South climate asynchrony.

223 A three-lead ECG was recorded throughout and the final 5 min of

224 Continuous three-lead Holter monitors with ST-segment analysis by a blind

225 rve as a substitute for the conventional tin-lead solder in all devices.

226 the number of recent successful fragment-to-lead (F2L) publications.

227 ides a tabulated overview of the fragment-to-lead literature published in the year 2015, together wit

228 Subsequently, structure-guided fragment-to-lead optimization led to the identification of a >100-fo

229 atural amino acid structures found in hit-to-lead and lead optimization campaigns and clinical stage

230 Successful SAR exploration in Hit-to-Lead and Lead Optimization efforts leading to the select

231 and cost of drug discovery within the hit-to-lead and lead optimization phases.

232 ly encountered in medicinal chemistry hit-to-lead and lead optimization.

233 the triage of candidate compounds in hit-to-lead campaigns.

234 Such library ideas support hit-to-lead design efforts for tasks like follow-up from high-t

235 We describe the hit-to-lead development of selective Bcl-XL inhibitors originat

236 excellent starting point for further hit-to-lead development.

237 hem as a promising starting point for hit-to-lead development.

238 strategies for fragment screening and hit-to-lead development.

239 iral drugs, overlooked in traditional hit-to-lead discovery efforts, may be responsible for these poo

240 A comprehensive hit-to-lead effort culminated in the discovery of 45h as a pote

241 -receptor, we herein report a de novo hit-to-lead effort on the identification of subnanomolar purine

242 We now describe a hit-to-lead effort resulting in the discovery of a potent and s

243 Systematic hit-to-lead efforts significantly improved potency and efficacy

244 represents a promising candidate for hit-to-lead follow-up in the drug-discovery process against Alz

245 Hit-to-lead in vitro optimization for target activity and molec

246 obust starting point for initiating a hit-to-lead medicinal chemistry effort.

247 zolopyridines as a starting point for hit-to-lead medicinal chemistry.

248 Hit-to-lead optimization and structure-activity relationship st

249 Traditional hit-to-lead optimization assumes that upon elaboration of chemi

250 an be considered as hit compounds for hit-to-lead optimization campaigns in drug discovery programs.

251 A hit-to-lead optimization effort was then initiated on derivativ

252 Structure based hit-to-lead optimization led to the identification of 5-(3,4-di

253 Hit-to-lead optimization of a new series of thienopyrimidine-ba

254 n, we describe the identification and hit-to-lead optimization of a novel class of tricyclic sulfonam

255 structure-activity relationships and hit-to-lead optimization of dual Top1-TDP1 inhibitors in the in

256 that provided robust guidance in the hit-to-lead optimization of small molecule LRRK2 inhibitors.

257 assess their applications in the EED hit-to-lead optimization process, large amount of thermodynamic

258 the attention on hit identification, hit-to-lead optimization, ADME profile evaluation, and the stru

259 based screening of compounds library, hit-to-lead optimization, computational and structure-based des

260 Through a process of hit-to-lead optimization, we report here the discovery of compo

261 ing antischistosomal hits for further hit-to-lead optimization.

262 gands from high throughput assays and hit-to-lead optimizations.

263 re-activity relationship (SAR) on the hit-to-lead path using in-house libraries and/or commercially a

264 ements existing methodologies for the hit-to-lead phase in fragment-based drug discovery.

265 SKR, we were able to re-evaluate the hit-to-lead process of cyclopentylamines as CCR2 antagonists.

266 was also based on residence time, the hit-to-lead process yielded compound 22a, a new high-affinity C

267 describe the identification process, hit-to-lead progression, and binding profiles of these selectiv

268 a chemical library, it showed a good hit-to-lead ratio and is an efficient early stage screening for

269 identification of the inhibitors, the hit-to-lead studies, and the emerged structure-activity relatio

270 HTS can significantly reduce cost and hit-to-lead time while yielding novel compounds with promising

271 f SMYD2 contributed significantly to "hit-to-lead" design efforts, culminating in the creation of pot

272 Twelve-lead ambulatory (Holter) electrocardiographic (ECG) moni

273 Twelve-lead ECGs during left bundle branch block and cardiac re

274 Twelve-lead ECGs were recorded and analyzed at years 0, 7, and

275 Twelve-lead electrocardiogram matched in 15 of 19 VTs between d

276 Twelve-lead electrocardiograms (ECG) of spontaneous VT often ar

277 Twelve-lead electrocardiograms were normal in 10 (53%) of the g

278 Twelve-lead electrocardiograms were recorded before study drug,

279 allograft rejection, we analyzed 249 twelve-lead-electrocardiograms, echocardiograms, hemodynamic pa

280 uded standard monitoring (five-electrode/two-lead electrocardiogram with ST segment trends and routin

281 Uranium-lead geochronology in detrital zircons and provenance an

282 Uranium-lead zircon data from lower Cambrian rocks located in no

283 A uranium-lead zircon age for a volcanic ash interstratified with

284 Here we apply uranium-lead (U-Pb) zircon geochronology to Deccan rocks and sho

285 Currently, uranium-lead zircon geochronology is the most powerful method fo

286 tio has fundamental implications for uranium-lead geochronology and cosmochronology.

287 Nineteen uranium-lead zircon ages of lower crustal gabbros from Atlantis

288 lithosphere cooling with the use of uranium-lead (U-Pb) thermochronology on volcanically exhumed low

289 nsive 2505 +/- 2.2-million-year-old (uranium-lead ratio in zircon) Archean ophiolite complex in the N

290 of the existing chronology based on uranium-lead dating and palaeomagnetic stratigraphy has recently

291 High-precision uranium-lead dating of zircons in gabbros from the Vema Fracture

292 ine sites in the Grand Canyon showed uranium-lead dating evidence for an old western Grand Canyon on

293 ic composition of zircons, for which uranium-lead and hafnium isotopic data provide age constraints,

294 pilation of ~120,000 detrital zircon uranium-lead (U-Pb) ages from global sedimentary deposits as a p

295 Here, we present new zircon uranium-lead (U-Pb) geochronologic constraints on the age and du

296 ave obtained identical single-zircon uranium-lead ages of 3470 +/- 2 million years ago for the oldest

297 lacial clast of A-type granite has a uraniun-lead zircon age of approximately 1440 million years, an

298 Both the site of ventricular-lead placement and timing with the atria have been manip

299 d, 4.7+/-4.3 versus 0.7+/-0.3 V; ventricular-lead, 3.0+/-3.3 versus 0.7+/-0.3 V).

300 ions in sphalerite from two contrasting zinc-lead ore systems.