ライフサイエンスコーパス: -mediated activation

1 We identify Neuropilin-1 (NRP-1)-mediated activation of KDR signaling through VEGF165 as

2 Thus, HIF-1-mediated activation of 5-HT signalling promotes axon reg

3 nhibitor substantially inhibits LFA-1/ICAM-1-mediated activation of Notch signaling.

4 Finally, RTA inhibits IL-1-mediated activation of NF-kappaB.

5 skeleton contributes to IRS-2- but not IRS-1-mediated activation of AKT by IGF-1.

6 K inhibitor CP-690550, suggesting that IL-10-mediated activation of AMPK is independent of PI3K and J

7 as well as IFN-gamma production by IL-12p70-mediated activation of natural killer cells, whereas miR

8 L-1R) expression, are refractory to IL-1beta-mediated activation in vitro and in vivo, and fail to re

9 a mediator of interleukin-1 receptor (IL-1R)-mediated activation of NFkappaB, TRAF6 has since been id

10 ulate its own expression and to limit CSF-1R-mediated activation of extracellular signal-regulated ki

11 annel expression, but not changes in Ca(2+) -mediated activation of SK channels, contributes to exace

12 IL-2-mediated activation of the Akt kinase and mTORc1 signali

13 irst time that IL10 suppresses Smad-miRNA-21-mediated activation of BM-FPCs and thus modulates cardia

14 -13 production strongly depends on the MK2/3-mediated activation of ERK1/2 and PI3K signaling.

15 transducer and activator of transcription 3-mediated activation of the focal adhesion kinase and its

16 (-/-) eosinophils demonstrate enhanced IL-33-mediated activation and effector functions.

17 ogates CGI-58 localization to LDs and CGI-58-mediated activation of ATGL.

18 itinase, DUB3, as a target of CDK4/6; CDK4/6-mediated activation of DUB3 is essential to deubiquitina

19 One involves cAMP/protein kinase A-mediated activation of the Src homology region 2 domain-

20 tion suppresses eosinophilic responses to Ab-mediated activation and has the potential to be used as

21 ts homologues RAP2.2 and RAP2.3 sustains ABA-mediated activation of ADH1 and activates hypoxia marker

22 P2 transcription factors can prolong the ABA-mediated activation of a subset of osmotic responsive ge

23 nt tropomyosin cofilaments affects the actin-mediated activation of NM-2B and the release of the ATP

24 ADP-mediated activation was not observed, although larger am

25 Ag-mediated activation of mast cells initiates signaling ev

26 ty of the ligand(s) responsible for such AHR-mediated activation within the gut remains to be firmly

27 Akt-mediated activation in macrophages was specific for Rac1

28 s, p70S6K and 4E-BP1, by increasing PI3K/Akt-mediated activation of Rheb-GTP via TSC2 suppression.

29 enesis and gene rescue studies show that Akt-mediated activation of PRAS40 via threonine 246 phosphor

30 mpact of PLD1 in tumor necrosis factor-alpha-mediated activation of monocytes after myocardial ischem

31 However, TNF-alpha-mediated activation of TonEBP did not cause induction of

32 Specifically, alpha6beta4-mediated activation of Src and STAT3 suppresses expressi

33 gment IgA production by integrin alphavbeta8-mediated activation of transforming growth factor-beta (

34 CCL20 expression is dependent on alphavbeta8-mediated activation of TGF-beta.

35 PARK2 depletion contributes to AMPK-mediated activation of endothelial nitric oxide synthase

36 ore, we discuss the control of anaphylatoxin-mediated activation of dendritic cells and allergic effe

37 y titres, NK cell-mediated ADCC and antibody-mediated activation of MIP-1beta in NK cells as the four

38 ally, we were interested in whether antibody-mediated activation through the classical pathway was a

39 stimulatory signal to T cells during antigen-mediated activation.

40 tochondrial biogenesis, contributing to aROS-mediated activation of the DDR and cell cycle arrest.

41 odulator protein, implicating a role for ATM-mediated activation of canonical NF-kappaB transcription

42 We further identified that bacterium-mediated activation of TRPC1 was dependent on Toll-like

43 ence of barttin and prevents further barttin-mediated activation.

44 s, suggest that the reaction occurs via base-mediated activation of HSA, followed by 1,2 aryl B-N mig

45 signal-regulated kinase signalling after BCR-mediated activation compared with healthy controls.

46 om classical MBCs becoming refractory to BCR-mediated activation and potentially interfering with the

47 ne deacetylase 6 (HDAC6) modulates TGF-beta1-mediated activation of the Notch pathway.

48 ist based on its ability to block (i) BigLEN-mediated activation of GPR171 in heterologous cells, (ii

49 s of T3SS2, which are likely induced by bile-mediated activation of the transcription factor VtrB.

50 ered action potentials in FSIs preceding BLA-mediated activation of MSNs.

51 rmore, B-RAF elimination inhibited C-RAF BxB-mediated activation of the mitogenic cascade.

52 study reveals a novel role for C5aR2 in C5a-mediated activation of mast cells and demonstrates that

53 ively, our findings demonstrate that calcium-mediated activation of the calcineurin pathway acts as a

54 CALR C terminus is required for mutant CALR-mediated activation of JAK-STAT signaling.

55 released from the mitochondria upon caspase-mediated activation of BID.

56 alidate the model by inhibiting beta-catenin-mediated activation of DPAGT1 expression and predicting

57 ng protein DDB2 is critical for beta-catenin-mediated activation of RNF43, which restricts Wnt signal

58 menin via cholecystokinin B receptor (CCKBR)-mediated activation of PKA.

59 blood monocytes, and that CD300c and CD300e-mediated activation was quantitatively different in neon

60 CD40-mediated activation for 2 hours stimulated the expressio

61 i-human CD40 mAb PG102 fails to trigger CD40-mediated activation, as well as impairs CD154-mediated C

62 cle reviews the current evidence for HA/CD44-mediated activation of RhoGTPase signaling and calcium m

63 lo-like kinase (Plk) control Cdc20- and Cdh1-mediated activation of the APC/C.

64 ranodal T cell migration, and dendritic cell-mediated activation of antiviral CD8+ T cells.

65 tosis was initiated by multiple myeloma cell-mediated activation of Notch signaling and was further a

66 produce less IFN-gamma in response to T cell-mediated activation than do CD56(bright) or CD56(dim)CD5

67 suggests that UAG is subject to target cell-mediated activation - a novel mechanism for manipulating

68 ghlighting a key role for effector Treg-cell-mediated activation of latent TGF-beta in suppression of

69 x 2 (mTORC2) is required for chemoattractant-mediated activation of adenylyl cyclase 9 (AC9), which c

70 eceptors results from inhibition of chloride-mediated activation.

71 In contrast, ChR2-mediated activation of BLA-vHPC projections significantl

72 e also demonstrate that KLF4 limits cleavage-mediated activation of Notch1.

73 We also show that CLEC5A-mediated activation of macrophages enhanced cytokine ela

74 e observe that FCRL4 expression enhances CpG-mediated activation of NF-kappaB signaling.

75 n RF mice a 12-h PCC shift to which the CREB-mediated activation of Per1, Per2 by glucagon modestly c

76 lucose concentrations by inhibiting the CREB-mediated activation of the gluconeogenic program in resp

77 ac ChIP-seq, reporter gene assays and CRISPR-mediated activation, that many of these regions function

78 gest that, under chronic pain states, CX3CR1-mediated activation of microglia drives the facilitation

79 grin-linked kinase to be essential for CXCL1-mediated activation of NLRP3 inflammasome.

80 rpesvirus 68 are defective in BCR- and CXCR4-mediated activation of the PI3K pathway, and this, we sh

81 Here, we have examined cytokine-mediated activation of NK cells during infection with tw

82 lls have differing requirements for cytokine-mediated activation, and both can contribute nonredundan

83 inflammatory response by promoting cytokine-mediated activation of the NF-kappaB pathway.

84 We have previously shown that cytokine-mediated activation of the MAP3K MLK3 stabilizes TRB3 pr

85 We found that, in contrast to cytokine-mediated activation, NIK stabilization by MACs did not i

86 versus activated macrophages where cytokine-mediated activation renders Mtb tolerant to four frontli

87 ansmission at direct pathway synapses and D1-mediated activation of motor activity.

88 oneogenic gene expression, whereas cyclin D1-mediated activation of CDK4 represses the gluconeogenic

89 Altogether, we present a DAG-mediated activation mechanism for TRPC4/5 channels tight

90 stance involves diacylglycerol-mediated (DAG-mediated) activation of protein kinase C-epsilon (PKCeps

91 olecular mechanism of cytochrome c- and dATP-mediated activation of Apaf-1.

92 show that AKAP function is required for DCC-mediated activation of PKA and phosphorylation of cytosk

93 dipogenesis in vivo and demonstrate that DEX-mediated activation of GR accelerates, but is dispensabl

94 Cytosolic DNA-mediated activation of the transcription factor IRF3 is

95 neurons, and (iii) feeding induced by DREADD-mediated activation of BigLEN containing AgRP neurons in

96 athoinhibition elicited by selective, DREADD-mediated activation of ArcN NPY/AgRP neurons.

97 n of POMC neurons diminishes, whereas DREADD-mediated activation of POMC neurons enhances CB1R-driven

98 activated by designer drug-mediated (DREADD-mediated) activation of these neurons increased physical

99 g the liver and intestine) to influence drug-mediated activation of the lipid regulator peroxisome pr

100 ecretion, which depended critically on DUOX1-mediated activation of epithelial epidermal growth facto

101 Thus, DUX4-mediated activation of Ret prevents myogenic differentia

102 First, EGF-mediated activation of EGFR blunted fusion kinase inhibi

103 &2 kinase activities reveals concomitant EGF-mediated activations of both kinases in HeLa cells.

104 Raft targeting of p110alpha allowed its EGFR-mediated activation by GPCRs.

105 ing complex allowed IL-33 to induce the EGFR-mediated activation of the MAP-kinase signaling pathway

106 tivated kinase alpha, abrogated endorepellin-mediated activation and co-localization of Beclin 1 and

107 ing assay that is capable of monitoring EPAC-mediated activation of cellular Rap1 in an isoform-speci

108 ERbeta represses ERalpha-mediated activation of the ERE and the RET promoter cont

109 EREG-mediated activation of EGFR enhanced nociception through

110 t expression of DUSP2 inhibits ERK3 and ERK4-mediated activation of its downstream substrate MK5.

111 d mice identify a critical role for estrogen-mediated activation of lung macrophage nitric oxide synt

112 glial cell line-derived neurotrophic factor)-mediated activation of ERK and AKT in MCF-7 cells.

113 phosphorylation of c-Src and subsequent FAK-mediated activation of ERK and AKT signaling pathways.

114 ce of IL-6 were also more susceptible to Fas-mediated activation-induced cell death in vitro.

115 that this integrin is crucial to elicit FBG-mediated activation of latent TGF-beta and subsequent ep

116 f mast cell function on repeated FcepsilonRI-mediated activation.

117 sue-like mast cell survival upon FcepsilonRI-mediated activation in vitro.

118 Herein, Nature's flavin-mediated activation of complex (poly)enes has been trans

119 These sequences provide EWS/FLI-mediated activation to reporter constructs, suggesting t

120 gration are regulated through the Arl4C-FLNa-mediated activation of Cdc42.

121 to the granules and lipid bodies during fMLP-mediated activation.

122 we demonstrate that miR-29 fine-tunes FOXA2-mediated activation of key lipid metabolism genes, inclu

123 duced ATP release and subsequent P2Y2/Gq/G11-mediated activation of downstream signaling that results

124 these two residues were essential for GAPDH-mediated activation of TNF receptor-associated factor 2

125 revealed that PKD1 is indispensable for GBS-mediated activation of MAPKs and NF-kappaB and subsequen

126 res guanine nucleotide exchange factor (GEF)-mediated activation of downstream Ras family small GTPas

127 -gHgL neutralizing antibodies can block gHgL-mediated activation of gB through different surface epit

128 ing nerve injury in mice, perhaps via a GPCR-mediated activation mechanism, and suggest that inhibiti

129 l as after receptor tyrosine kinase- or GPCR-mediated activation of ERK1/2, suggesting that it is a c

130 nduced positive GC response element [(+)GRE]-mediated activation of transcription are partially under

131 ations of interleukin-8 and VEGF due to GRM1-mediated activation of the AKT-mTOR-HIF1 pathway.

132 ificantly enhanced expansion because of GzmB-mediated activation-induced cell death of wild-type CD4(

133 cores, which release H2S directly upon H2O2-mediated activation.

134 (HCMV) and that THY-1 is important for HCMV-mediated activation of phosphatidylinositol 3-kinase (PI

135 We then studied the mechanism of HDAC1-mediated activation.

136 gest that shifting constitutive hFcgammaRIIA-mediated activation to ITAMi signaling could ameliorate

137 the responsiveness to NRG1 and sustained HGF-mediated activation of AKT.

138 from this domain competitively inhibits HopQ-mediated activation of the Cag virulence pathway, as gen

139 mechanisms, we observed that heregulin (HRG)-mediated activation of HER2, or HER2 overexpression, res

140 ote PABP recruitment and necessary for ICP27-mediated activation.

141 ressed the combined effects of IL-33 and IgE-mediated activation on mouse and human mast cells.

142 d for growth, development, survival, and IgE-mediated activation.

143 tic reactions by essentially eliminating IgE-mediated activation of mast cells.

144 ducing mast cell responses and enhancing IgE-mediated activation.

145 tantially different releasates following IgE-mediated activation.

146 Suppression of IgE-mediated activation is a common feature of all desensiti

147 viously reported effects of TGF-beta1 on IgE-mediated activation, demonstrate that TGF-beta1 can prov

148 nistically, the omega-3 epoxides promote IgE-mediated activation of mast cells by downregulating Srci

149 estive of a direct link between repeated IgE-mediated activation of mast cells and chronic allergy.

150 Collectively, our results indicate that IgE-mediated activation of basophils and the release of baso

151 on, rendering mast cells unresponsive to IgE-mediated activation.

152 TspB appeared to inhibit IgM-mediated activation of the classical complement pathway,

153 MEDI5117 inhibited IL6-mediated activation of STAT3, suppressing the growth of

154 dopamine control, through a concomitant ILC-mediated activation of the pmVTA.

155 Such bimolecular indole-mediated activation of the human AHR within the gastroin

156 To directly compare inflammasome-mediated activation in different types of macrophages, w

157 scription of pro-IL-1beta mRNA, inflammasome-mediated activation of caspase-1, and secretion of matur

158 Whereas inflammasome-mediated activation is heavily studied in hematopoietic

159 In the liver, insulin-mediated activation of the phosphatidylinositol 3-kinase

160 ned whether Elmo2 contributes to the insulin-mediated activation of Rac1 and Akt.

161 that alphaE-catenin inhibits beta4 integrin-mediated activation of SRC tyrosine kinase.SRCis the fir

162 of phorbol 12-myristate 13-acetate/ionomycin-mediated activation signals.

163 Thus, our data show that IR-mediated activation of ErbB2 and induction of 14-3-3zeta

164 ined native chemical ligation and isonitrile-mediated activation strategies.

165 n the overexpression of IFN-beta: first, JNK-mediated activation of c-jun, which binds to the IFN-bet

166 s triggers a signaling cascade involving JNK-mediated activation of cJun that regulates tlx3, a gluta

167 We show that MUC1-C promotes NF-kappaB-mediated activation of TAK1 transcription and, in a posi

168 ion and replication by suppressing NF-kappaB-mediated activation of viral transcription.

169 anced upon PN/INTEGRIN/focal adhesion kinase-mediated activation of PI3K and/or ERK, an effect confir

170 pression in EMT cells through p38 MAP kinase-mediated activation of the JunB transcription factor.

171 BA stimulates ATP release through the LANCL2-mediated activation of adenylate cyclase.

172 LasR-mediated activation occurs at the distal promoter site,

173 Ligand-mediated activation of the androgen receptor (AR) is cri

174 eptor is required for its appropriate ligand-mediated activation by PDGF-AA.

175 ARbeta/delta in cancer is dictated by ligand-mediated activation.

176 eceptors, allowed cross-reactivity of ligand-mediated activation and growth.

177 ed by PPARD that failed to respond to ligand-mediated activation.

178 nterface without the need for heat- or light-mediated activation.

179 The initial visible light-mediated activation of a variety of monosubstituted or d

180 inhibition of NF-kappaB abolished LINC00305-mediated activation of cytokine expression.

181 BTKB66 potently inhibited lipopolysaccharide-mediated activation of bone marrow-derived neutrophils a

182 These findings suggest that LMP1-mediated activation of IGF1R contributes to the ability

183 Furthermore, LPC-mediated activation of type II NKT cells leads to anergy

184 LPS-mediated activation of Toll-like receptor 4 (TLR4) in ma

185 C in vivo, and UBE2L3 is essential for LUBAC-mediated activation of NF-kappaB.

186 to determine whether UBE2L3 regulates LUBAC-mediated activation of NF-kappaB, and determine the effe

187 aling pathway analysis revealed the p38 MAPK-mediated activation of a calcium independent phospholipa

188 Whereas NLRX1 suppressed MAVS-mediated activation of IRF3, it conversely facilitated v

189 ly, the 5' splice site is required for MBNL1-mediated activation of upstream intron removal, although

190 One such event is MBNL1-mediated activation of insulin receptor exon 11 inclusio

191 The mechanism of MBNL1-mediated activation of exon inclusion is unknown.

192 Microbiota-mediated activation of the innate immune responses throu

193 ibition in human THP1 cells enables microRNA-mediated activation.

194 possibly through prevention of mitochondria-mediated activation of DDR.

195 Small molecule-mediated activation of GCase was effective at reducing a

196 Perforated patch-clamp recordings of MOPr-mediated activation of G-protein-activated inwardly rect

197 Finally, we demonstrate that the eMaSC-MVs-mediated activation of the Wnt/beta-catenin signaling pa

198 e-dependent manner, has no role in the Mxr1p-mediated activation of ACS1 expression.

199 e rapidly produce IL-10 as a result of MyD88-mediated activation of MEK/ERK/RSK and p38.

200 an senescent fibroblasts, DDR precluded MYOD-mediated activation of the myogenic program.

201 ing myoblast determination protein 1 (MYOD1)-mediated activation of myogenic differentiation.

202 ease in EC50 for NK group 2 member D (NKG2D)-mediated activation, allowing NK cells to respond to low

203 ily kinases (SFKs) are involved in both NMDA-mediated activation of TrkB- and TrkB-mediated tyrosine

204 Moreover, our results showed that NMDA-mediated activation of the small G-protein Ras is necess

205 Moreover, MK-801 inhibits NMDAR-mediated activation of p38-MAPK and dephosphorylation of

206 We also demonstrate Orco expression and Orco-mediated activation of spermatozoa in the yellow fever m

207 the degradation of ribosomal proteins by p17-mediated activation of E3 ligase MDM2 that targets ribos

208 The PC1-p30-mediated activation of Src/STAT3 was independent of JAK

209 n cancer cells and subsequently promotes p53-mediated activation of its transcriptional targets such

210 phagy in the development of PDAC through p62-mediated activation of NRF2.

211 Key to pAg-mediated activation of Vgamma9Vdelta2 T cells is the but

212 How the switch from Pax-mediated activation to repression is regulated remains p

213 on and pre-eclampsia were defective in PCSK6-mediated activation.

214 hile it is widely believed that direct (PDGF-mediated) activation is the primary mode of activating P

215 scovered a functional pathway involving PDK1-mediated activation of MRCKalpha, which links EGF signal

216 served genes are regulated by classical PhoP-mediated activation and are invariant in promoter archit

217 LMP1-transformed cells led to phosphorylase-mediated activation of the PI3K/AKT pathway and inductio

218 iviral responses by inducing phosphorylation-mediated activation of protein kinase R (PKR) and stimul

219 ation of RhoA in this system depends on PI3K-mediated activation of GEF-H1 and p115 RhoGEF.

220 ockdown of LPCAT3 in mice affected PPARdelta-mediated activation of several hepatic genes involving i

221 Following PREX2-mediated activation of Rac1 by the second messengers PIP

222 in PTPRZ-deficient mice, suggesting that PTN-mediated activation of RAS was dependent upon signaling

223 However, the molecular mechanism of PXR-mediated activation of ethanol (EtOH)-induced steatosis

224 on by a mechanism that involves loss of RAP1-mediated activation of beta1 integrin.

225 and that Rap1 positively regulates the RasC-mediated activation of TORC2 in Dictyostelium.

226 Receptor-mediated activation of the Galpha subunit of heterotrime

227 ssential for the P2X purinoceptor 7 receptor-mediated activation of unconventional protein secretion.

228 Moreover, the mutations ablated receptor-mediated activation of serum response factor luciferase,

229 cells, compound 211 prevents T-cell receptor-mediated activation of Lck, Zap-70, and mitogen-activate

230 Toll-like receptor- and complement receptor-mediated activation.

231 regulation and initiation of death receptor-mediated activation of programmed cell death is the aspa

232 action through EP2 prostaglandin E2 receptor-mediated activation of PKA in pulmonary fibroblasts.

233 is process is underpinned by 5-HT1A receptor-mediated activation of G-protein-coupled inwardly rectif

234 nucleotide exchange activity yet no receptor-mediated activation of nucleotide exchange.

235 2 (Tyk2), resulting in blockade of receptor-mediated activation of the adjacent catalytic domain.

236 e technology is suited for studying receptor-mediated activation in cell lines endogenously expressin

237 rotein plays a critical role in the receptor-mediated activation of downstream germination events.

238 This suggests that unlike receptor-mediated activation, helix 5 rotation and translocation

239 tion, likely by suppressing liver X receptor-mediated activation of steroidogenic acute regulatory pr

240 Relaxin-mediated activation of RXFP1 requires multiple coordinat

241 demonstrated that Norbin promotes the P-Rex1-mediated activation of endogenous Rac1 upon stimulation

242 RIPK3-mediated activation of PGAM5 promotes the expression of

243 The results show that ROS-mediated activation of JAK2 is required for P. gingivali

244 enable the autocatalytic, and in general ROS-mediated, activation of (1)O2 sensitization providing a

245 ton's tyrosine kinase was required for RP105-mediated activation of Akt phosphorylation and TNF relea

246 of IL-36gamma and highlight that cathepsin S-mediated activation of IL-36gamma may be important in th

247 al protease-activated receptors, cathepsin S-mediated activation of MrgprC11 did not involve the gene

248 hondrial biogenesis, possibly through SERCA2-mediated activation of AMP-activated protein kinase path

249 MYO6 localization to invasion foci, and SopE-mediated activation of PAK recruited MYO6 to actin-rich

250 use of mitochondrial reactive oxygen species-mediated activation of AMP kinase (AMPK) and the nuclear

251 We demonstrate reactive oxygen species-mediated activation of AMP-activated kinase in Huh7.5 ce

252 ted the key role of this SRE motif in SREBP2-mediated activation of C-ACSL1 gene transcription.

253 ner, which occurs in addition to the Stachel-mediated activation.

254 ned strong evidence in favor of the HN stalk-mediated activation of paramyxovirus fusion.

255 iggering, a notion consistent with the stalk-mediated activation model of paramyxovirus fusion.

256 w insights into the role of acetylated STAT3-mediated activation of IGF2 transcription in HDI resista

257 STING-mediated activation of the IFN-I pathway through the TBK

258 tress in beta-cells by suppressing ER stress-mediated activation of all three branches of unfolded pr

259 Our data demonstrate that stretch-mediated activation of inflammatory pathways is at least

260 Dilp3 is uniquely required for the sugar-mediated activation of TOR signalling and suppression of

261 ell as after their inactivation by sulfatide-mediated activation of type II NKT cells.

262 ich can be prevented by topical sulforaphane-mediated activation of NRF2.

263 TAK1 with TRAF6, which is necessary for TAK1-mediated activation of NF-kappaB.

264 Furthermore, TAK1-mediated activation of JNK is essential to prevent oxida

265 These studies reveal the importance of talin-mediated activation of integrins for renal ischemia-repe

266 ts imply that cell cycle arrest inhibits Tax-mediated activation of sense transcription without affec

267 Consistently, TBL1XR1-mediated activation of Wnt signaling was up-regulated by

268 non-innate T cells by T cell receptor (TCR)-mediated activation.

269 ussed, we investigated how gp120 affects TCR-mediated activation of human CD4(+) T cells by agonistic

270 f p38 with UV or osmotic shock mitigated TCR-mediated activation by phosphorylation and cytoplasmic r

271 Thus, TCR-mediated activation of CD4(+) TILs results in alternativ

272 everal pathways and signaling nodes upon TCR-mediated activation, with low phosphorylation of CD3zeta

273 t be induced in conventional T cells via TCR-mediated activation or inflammatory challenge.

274 administered as a prodrug with sustained Tf-mediated activation and selectivity in inhibiting HGP.

275 TGFbeta-mediated activation of autophagy has recently been sugge

276 Mechanistically, GRM3 antagonizes TGFbeta-mediated activation of protein kinase A and inhibition o

277 I receptor sensitizing PDAC cells to TGFbeta-mediated activation of p38 and SMAD signals.

278 at they are fully able to respond to TGN1412-mediated activation.

279 ikely due to its ability to inhibit thrombin-mediated activation of FV and FVIII.

280 he contribution of PAR1 and PAR4 to thrombin-mediated activation of the platelet fibrin receptor (GPI

281 TLR-mediated activation of dendritic cells (DCs) is associat

282 Although TLR-mediated activation of MZ B is known to trigger humoral

283 ults define a differential regulation of TLR-mediated activation and differentiation of MZ B cells by

284 lipoylated E2 subunit of PDH to suppress TLR-mediated activation of host macrophages by bacterial lip

285 ic cells (DCs) and plasmacytoid DCs upon TLR-mediated activation and detectable by Nkrp1g, which damp

286 er the rate of IFN-gamma production upon TLR-mediated activation.

287 he lungs can be sustained by persistent TLR4-mediated activation of lung conventional dendritic cells

288 The TLR8-mediated activation of IRF5 was dependent on TAK1 and Ik

289 egression and determined that defective TLR9-mediated activation of IDO1 induction is associated with

290 appears to be of crucial importance for TLR9-mediated activation of Syk.

291 Here, we demonstrate that TNFalpha-mediated activation of NF-kappaB in the respiratory epit

292 binding, and this suggests that upon TRIM25-mediated activation of RIG-I, RIG-I moves away from TRIM

293 This downregulation, in turn, inhibits TRPA1-mediated activation of FGFR2, hindering the metastatic p

294 cular cells was due to the inhibition of TSH-mediated activation of the mTOR complex 1/ribosomal prot

295 Our results suggest that TSLP-mediated activation of human nasal mucosal CD1c(+) DCs t

296 its ability to directly regulate urokinase -mediated activation of plasminogen (Pg).

297 Combined, our results indicate that UVB-mediated activation of TC-PTP plays an important role in

298 e identity of LEC progenitors and that Vegfc-mediated activation of Vegfr3 signaling is necessary to

299 ation but is a specific requirement for WASP-mediated activation.

300 sduction of SCN slices showed that the ZFHX3-mediated activation of AT motifs is circadian, with decr