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1 elatively few PD-1+ (programmed cell death 1-positive) T cells, an immunophenotypic pattern also obse
3 Of note, Optn was recruited to Atg12-5-16L1-positive puncta, and interacted with Atg5 and also with
4 We also found that the number of Atg12/16L1-positive puncta and recruitment of the Atg12-5-16L1 comp
6 the DDC-stimulated number of cytokeratin-19-positive cells in the liver of wild-type animals was sli
7 for human epidermal growth factor receptor 2-positive (luminal and nonluminal) tumors (15% v 19%; P =
11 l tissues from anti-citrullinated protein Ab-positive arthralgia, undifferentiated arthritis (UA), ea
13 sizes for group differences (Cohen d; Abeta-positive impaired vs. Abeta-negative normal) were evalua
16 ositive cells, and alpha-smooth muscle actin-positive blood vessels were assayed at postoperative day
18 GA1 signaling promotes the survival of ALDH1-positive stem-like cells and cooperates with TGFbeta to
19 4 patients with metastatic or inoperable ALK-positive IMT received crizotinib orally twice daily.
20 dy, 26 patients with relapsed/refractory ALK-positive ALCL and 14 patients with metastatic or inopera
21 latelet-derived growth factor receptor-alpha-positive cells, and alpha-smooth muscle actin-positive b
24 volume (both including and excluding amyloid-positive participants), group differences in amyloid upt
25 agement of hepatitis B virus (HBV) e antigen-positive viremic patients with normal liver function and
26 ignificant decrease in THP-, NKCC2- and AQP1-positive loop of Henle nephron segments in mutant DeltaS
28 AR and suppresses the growth of multiple AR-positive, but not AR-negative, prostate cancer cells.
30 with newly diagnosed T1D and in autoantibody-positive at-risk children with impaired glucose toleranc
31 eriostin and transforming growth factor beta-positive cells within Asm bundles, in addition to lower
32 describe 1) the use of enrichment (biomarker-positive patients) and a randomized controlled design by
36 y, and tract-tracing analysis revealed Cadm1-positive innervation of POMC neurons via afferent projec
37 d protein levels in cells infected with cagA-positive infections compared to cells infected with eith
38 on in Parkinson's disease, and the calbindin-positive dorsal tier, which is relatively resilient.
41 ell lines, discriminating between the cancer-positive and -negative cells, without any amplification
43 tive T cells to recognize and eliminate CD19-positive acute lymphoblastic leukemia (ALL) blasts, was
45 ically confirmed, previously untreated, CD20-positive grade 1, 2, or 3a follicular lymphoma; Eastern
46 dy, adults with relapsed or refractory, CD22-positive, Philadelphia chromosome (Ph)-positive or Ph-ne
47 ng hypertrophic-like scars, whereas few CD26-positive cells were present in the regenerated gingival
49 a conventional MMAE warhead destroyed CD276-positive cancer cells, but were ineffective against tumo
50 noclonal antibody construct that enables CD3-positive T cells to recognize and eliminate CD19-positiv
51 , reduced neuronal density, perivascular CD3-positive T-lymphocyte clustering, and fibrinogen extrava
52 trial, we enrolled adult patients with CD30-positive mycosis fungoides or primary cutaneous anaplast
54 ded to engage and render gluten-specific CD4-positive T cells unresponsive to further antigenic stimu
58 er having been contact-traced by a chlamydia-positive partner were more likely to have CVM dominated
59 lockade can suppress Philadelphia chromosome-positive leukemia in mice, suggesting that this therapeu
60 les, in addition to lower numbers of chymase-positive mast cells in the submucosa compared to patient
61 eriments indicated that the majority of COL1-positive fibroblasts stem from a pool of SOX9-expressing
62 H in spheroidal tissue growths of connexin43-positive pancreatic cancer Colo357 cells during light-co
63 lotus tetragonolobus lectin-negative/p-Creb-positive cyst segments (re)-expressed Ncam1, Pax2, and S
65 ta available expectorated infectious culture-positive cough aerosols in the respirable range (<5 mum)
67 The proportions of participants with culture-positive PTB initiated on appropriate TB treatment withi
68 to rigid substrates with Gaussian curvature-positive for spheres and negative for saddles-has proven
69 By immunohistochemistry, the number of CXCR3-positive mononuclear cells was higher in skin and intest
73 PCs were further differentiated into DARPP32-positive neurons, these HD neurons were more susceptible
74 peptide can decrease aldehyde dehydrogenase-positive BCSCs and mammosphere formation capacity in SUM
76 f high-affinity signaled CD4(+)CD8(+) double-positive thymocytes and CD8(+) and CD4(+) single-positiv
77 ve selection of immature CD4(+)CD8(+) double-positive thymocytes and their commitment to the CD4(+)CD
78 is protein expression is increased in double-positive thymocytes undergoing positive selection and is
79 elective targeting and eradication of double-positive human NCI-H358 non-small cell lung cancer targe
80 imilar with respect to the numbers of double-positive thymocytes, CD4(+)CD8(-) T cells, regulatory T
82 ing features and mutation status (e.g., EGFR-positive [EGFR+] vs. EGFR-negative) was assessed using t
84 Greater than 50% of estrogen receptor (ER)-positive breast cancers coexpress the progesterone recep
87 neity by localizing immunohistochemically ER-positive metastases that lack receptor-binding functiona
88 sal ErbB2 receptor tyrosine kinase 2 (ErbB2)-positive breast cancer (ErbB2(KI)), which exhibits aberr
90 ng clusters of risk TFs associated with ESR1-positive and -negative breast cancer can physically inte
92 of leukocytes, platelets, and tissue factor-positive (TF(+)) microvesicles (MVs) are all potential f
95 nts incorrectly treated with ART after false-positive diagnosis (e.g., medication toxicities); includ
96 hnical parameters, number of true- and false-positive and true- and false-negative results were extra
97 positive predictive values (PPVs) and false-positive rates, with a lack of precision in accuracy est
99 ng amounts of CCDs sufficient to cause false-positive test results up to 2 kUA/L with nonglycosylated
100 indicated by the false-negative (FN), false-positive (FP), and fixation loss (FL) rates, on global i
104 tential harms of treatment (ie, higher false-positive rates in low-prevalence populations) as small.
106 e this approach to show a reduction in false-positive peaks as well as improved consistency across la
107 150 (95% CI, 146-154) had one or more false-positive tests equating to a number needed to harm from
108 ects with F0-F2 fibrosis, the rates of false-positive LSM results for F3-F4 fibrosis increased accord
110 for gelatin, problems associated with false-positive and false-negative results, inconsistencies and
111 tcomes included number of infants with false-positive diagnoses linked to ART per 1,000 ART initiatio
112 In comparison to spoligotyping of acid-fast-positive MGIT cultures, percent agreement between positi
113 ion-free survival in patients with EGFR FISH-positive cancer and overall survival in the entire study
114 subgroup analyses of patients with EGFR FISH-positive squamous-cell carcinoma cancers are encouraging
117 numbers of antigen-specific CD8(+) IFN-gamma-positive cells following injection into BALB/c mice.
118 FNgamma drives recruitment of TRIM21 to GBP1-positive Toxoplasma vacuoles, leading to Lys63-linked ub
121 p testing, all glutamate dehydrogenase (GDH)-positive specimens, regardless of fecal toxin result, fr
122 cohort studies in the literature, 8% of gene-positive patients were published to have double mutation
125 in family, which is spread widely among gram-positive bacteria; and suggests approaches to target RRN
126 , uncultivable asaccharolytic anaerobic Gram-positive rods and other uncultivable Gram-negative rods,
127 rains, including both Gram-negative and Gram-positive bacteria, showing great potential for applicati
129 successfully monitor the growth of both gram-positive (Staphylococcus aureus and Streptococcus pyogen
130 formation of competence-induced pili in Gram-positive bacteria and corroborate the remarkable structu
131 ever, the mechanisms of MV formation in Gram-positive bacteria are unclear, as these cells possess a
135 tibacterial activity against a panel of Gram-positive and Gram-negative bacteria revealed structure-a
141 proves outcome in patients with ERBB2 (HER2)-positive metastatic breast cancer; a clinically effectiv
143 ities of TILs in patients with advanced HER2-positive breast cancer treated with either pertuzumab or
145 d >/=18 years) with centrally confirmed HER2-positive advanced breast cancer previously treated with
147 B2/HER2-negative BrCa switched to ERBB2/HER2-positive with 1 BrM acquiring ERBB2/HER2 amplification a
151 butes to an enhanced HER2 expression in HER2-positive breast cancers with HER2 gene amplification and
152 report evaluating (89)Zr-trastuzumab in HER2-positive EGA; here, we evaluate the safety, pharmacokine
153 egative tumors, 82.8% of luminal B-like HER2-positive tumors, 21.3% of HER2-enriched tumors, and 7.8%
154 ard of care for first-line treatment of HER2-positive advanced gastric cancer, there is no establishe
155 resection of a brain metastasis proved HER2-positive disease, confirming that the (89)Zr-pertuzumab
156 ent of patients with previously treated HER2-positive advanced breast cancer, and validate HER2 as a
158 placebo-controlled trial, patients with HER2-positive early breast cancer were randomly assigned to r
159 ated for the treatment of patients with HER2-positive metastatic breast cancer previously treated wit
160 prediction of outcomes in patients with HER2-positive metastatic breast cancer randomized to an antib
161 imaging of the brain for patients with HER2-positive or triple-negative subtypes and extracranial me
162 tive breast cancers and correlates with HER2-positive status in human ductal carcinoma in situ (DCIS)
163 performed on murine xenografts of U87MG (HGF-positive, MET-positive) and MKN45 (HGF-negative, MET-pos
166 ately half of 40 tumor specimens from 23 HIV-positive and 17 HIV-negative patients (29 men and 11 wom
169 South Africa, HRQoL scores were lower in HIV-positive individuals who were aware of their status but
171 with HIV know their status, 90% of known HIV-positive individuals receive sustained antiretroviral th
172 randomised controlled trial in ART-naive HIV-positive patients with CD4 cell count of more than 500 c
176 scuss viral load monitoring for pregnant HIV-positive women and those breastfeeding; ART treatments c
177 clusters (58 cluster-years) and referred HIV-positive participants to trial clinics for ART (fixed-do
178 e to have much higher rates of ESRD than HIV-positive whites, which could be attributed to the APOL1
179 years, 62 (78.5%) were unaware of their HIV-positive status, 76 (96.2%) were not on antiretroviral t
180 Patients with human papillomavirus (HPV)-positive head and neck squamous cell carcinoma (HNSCC) h
182 repair, CHK1 and Wee1, are suppressed in HPV-positive cells, providing an explanation for why this mi
183 ion for why this microRNA is targeted in HPV-positive cells.IMPORTANCE We describe here for the first
184 In Africa, HPV 16 accounted for 13% of HPV-positive WHIV with normal cytological findings, but this
186 tively poor prognosis in comparison with HPV-positive disease, with decreased locoregional control an
191 33nmol/l, range = 0.02-5.14) than CASPR2-IgG-positive specimens (0.10nmol/l, range = 0.00-0.45, p < 0
192 l hyperintensity was more common in LGI1-IgG-positive (41%) than in CASPR2-IgG-positive patients (p =
194 Samoa and Puerto Rico, more than 80% of IgM-positive results were unspecified flavivirus infections.
195 lcium/calmodulin-dependent protein kinase II-positive principal cells as well as of parvalbumin- or s
196 We report recruitment of mannosidase-II-positive Golgi-derived vesicles during uptake of diverse
198 iminate critically ill adults with infection-positive versus infection-negative systemic inflammation
199 sues displayed significantly smaller insulin-positive areas, lower proportion of beta-cells positive
200 CMDR boost, vaccine-induced gamma interferon-positive (IFN-gamma(+)) Gag-specific T-cell responses we
203 In vivo studies were performed in PD-L1-positive, PD-L1-negative, and mixed tumor-bearing severe
206 oup (ECOG) performance status of 0 or 1, MET-positive tumours (>/=25% of tumour cells with membrane s
207 , MET-positive) and MKN45 (HGF-negative, MET-positive) and 4 patient-derived xenografts (MET-positive
208 urine xenografts of U87MG (HGF-positive, MET-positive) and MKN45 (HGF-negative, MET-positive) and 4 p
213 FC showed similar 5-year EFS and OS for MRD-positive and -negative patients using an MRD threshold o
215 argetable antioxidant enzyme in APC-mutation-positive colorectal cancer.2-Cys peroxiredoxin (Prx) enz
216 promoter methylation levels in CDH1 mutation-positive families, including penetrants, non-penetrants
217 approximately 0.8% of unrelated NF1 mutation-positive probands in the University of Alabama at Birmin
221 a high ratio of podocin-positive to nephrin-positive urinary EVs (podocin(+) EVs-to-nephrin(+) EVs r
224 rmone receptor-positive, HER2-negative, node-positive breast cancer, the MammaPrint assay may be used
225 t trastuzumab for adjuvant treatment of node-positive, human epidermal growth factor receptor 2-posit
228 pithelial nerve regeneration and substance P-positive nerve density in both wounded and unwounded eye
231 ally activating somatostatin- or parvalbumin-positive interneurons, even transiently during the delay
234 patients with clinically diagnosed ARN, PCR-positive for herpes simplex virus or varicella zoster vi
238 bility to stimulate, and the complemented PF-positive T. denticola strain restored the activation.
239 CD22-positive, Philadelphia chromosome (Ph)-positive or Ph-negative B-cell acute lymphoblastic leuka
240 t shares significant overlap with that of Ph-positive (Ph(+)) ALL and is suggestive of activated kina
243 regnancies contained a high ratio of podocin-positive to nephrin-positive urinary EVs (podocin(+) EVs
246 arance kinetics but identical uptake in PSMA-positive tissues in the LNCaP xenograft model (1 h after
247 iling view is that striatal parvalbumin (PV)-positive interneurons primarily function to downregulate
248 nalization, GPRC6A is recycled via the Rab11-positive slow recycling pathway, which may be responsibl
250 Furthermore, intact G1/S transition (Rb-positive and low-molecular-weight isoform of cyclin E (c
251 for those living in the household of an RDT-positive individual and 1.64 (1.0-2.8; P = .06) for thos
253 led to sustained expansion of IL-33 receptor-positive kidney ILC2s and ameliorated adriamycin-induced
255 mC, 0.55), but mainly for estrogen receptor-positive disease (IQ-OR, 1.44; 95% CI, 1.16 to 1.79; P f
257 ent-derived xenograft, the estrogen receptor-positive model T126, was chosen to generate in vivo mous
258 mor to avoid reexcision in estrogen receptor-positive progesterone receptor-positive cancer and 63% f
259 treatment in patients with hormone receptor-positive advanced breast cancer who were not given dexam
261 to hormone receptor status (hormone receptor-positive vs hormone receptor-negative), nodal status (0
265 or cytologically confirmed hormone-receptor-positive, HER2-negative, locally advanced or metastatic
266 ogen receptor-positive progesterone receptor-positive cancer and 63% for estrogen receptor-negative p
267 ing approach where mRNA from PGE2-G response-positive and -negative cell lines was subjected to trans
269 lammatory cytokine secretion from other ROCK-positive cell types, corroborating the selective in vivo
276 their commitment to the CD4(+)CD8(-) single-positive stage are impaired in Themis(-/-) mice, suggest
277 election and is sustained in immature single-positive thymocytes, despite the strong decrease in Them
278 l cell lung cancer target tumors over single-positive, non-target NCI-H358-HER2 CRISPR knock out tumo
279 ion of alpha-smooth muscle actin (alpha-SMA)-positive myofibroblasts that produced ECM proteins, incl
282 s as well as of parvalbumin- or somatostatin-positive interneurons to study the effects of such repet
284 umor uptake were quantified using SUVmaxPSMA-positive lesions were detected in 12 of 12 prostate canc
285 hat sits at the intersection of several task-positive networks (eg, central executive network, CEN),
287 teen studies reported the proportion of test-positive patients who completed colonoscopy compared wit
288 higher frequencies of MHC class II tetramer-positive CD4(+) T cells in HIV controllers than progress
289 persistent, and specific accumulation in TF-positive BXPC-3 tumors, PET imaging using (89)Zr-Df-ALT-
290 onstrated >300,000 tyrosine hydroxylase (TH)-positive grafted cells per side with normalized striatal
291 method, a CT cutoff of 26.35 detected toxin-positive samples with a sensitivity, specificity, positi
292 en who were contact-traced by C. trachomatis-positive sex partners at the STI outpatient clinic in Am
293 expansion of a polyclonal pool of transgene-positive functional T cells and sustained gene marking i
296 he (68)Ga-DOTATOC PET/CT was considered true-positive if the positive primary site was confirmed by h
299 uitment of the Atg12-5-16L1 complex to Wipi2-positive puncta are reduced in Optn-deficient cells.
300 (G-CSF) levels in the amniotic fluid of ZIKV-positive pregnant women with neonatal microcephaly.
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