コーパス検索結果 (left1)
通し番号をクリックするとPubMedの該当ページを表示します
3 wild-type serotype 3 strain and the capsule-switched mutant behaved similarly, whereas in the lungs
10 with a lentiviral construct encoding a class-switched anti-HIV IgA (b12-IgA) into the humanized bone
11 st be exquisitely controlled because a class-switched B cell cannot revert back to the parent isotype
16 ant mice fail to produce high-affinity class-switched antibodies and generate memory B and long-lived
20 ined by the formation of high-affinity class-switched memory B cells and long-lived antibody-secretin
23 However, the number of high-affinity, class-switched Ab-forming cells was severely decreased in the
24 nduce B cells secreting high-affinity, class-switched antibodies during germinal center (GC) reaction
25 s for the generation of high-affinity, class-switched antibodies during T cell-dependent antibody res
26 bited the production of high-affinity, class-switched antibodies, but not the production of low-affin
29 orting the induction of high-affinity, class-switched antibody responses, long-lived plasma cells, an
30 (Tfh) cells potentiate high-affinity, class-switched antibody responses, the predominant correlate o
31 excessive production of high-affinity, class-switched autoantibodies and to the high incidence of B c
36 e, B cell-deficient, Ab-deficient, and class-switched Ab-deficient mice with attenuated Salmonella an
37 proliferation markers (Ki-67(+)), and class-switched B cells (IgG(+)); and (5) both TNFRSF17 mRNA an
39 d numbers of marginal zone B cells and class-switched cells, and were associated with decreased antib
41 This may imply that CD4 T cells and class-switched IgG antibodies are more relevant for generating
42 oted homeostatic production of IgM and class-switched IgG antibodies to microbial capsular polysaccha
43 +) B cells, including IgM(+) naive and class-switched IgG memory B cells, with a concomitant increase
44 Numbers of total memory (CD27(+)) and class-switched memory B cells (IgM(-)) were significantly redu
46 molecule expression between naive and class-switched memory B cells, indicating their potential to i
49 s-associated, somatically mutated, and class-switched pathogenic autoantibodies are generated in spon
51 (healthy donors) MHC-II expression as class-switched memory B cells and intermediate costimulatory m
52 ng T cells and significantly augmented class-switched HSV-specific antibody responses compared with t
53 etic mechanisms, valproic acid blunted class-switched and hypermutated T-dependent and T-independent
55 memory compartments, characterized by class-switched IgG and high-affinity Abs, are the basis for su
56 in the immunoglobulin (Ig)D(-)CD27(+) (class-switched) memory B-cell compartment that normally arises
57 of somatic mutations in CD19+IgD-CD27+ class-switched memory B cells in RV-specific memory B cells, s
60 tingly, in the absence of conventional class-switched memory B cells, the circulating EBV load was co
65 e hypothesized that clonally expanded, class-switched IgG4-positive B cells and plasma cells could be
67 iple MHC disparities, cognate help for class-switched alloantibody may also be provided by CD4 T cell
69 ive repertoire are apparent mainly for class-switched B cells and not for IgM germinal center, IgM me
71 spontaneous germinal center formation, class-switched autoantibodies, renal histopathology, and early
74 ion to enhancing mucosal immunity, IgD class-switched B cells enter the circulation to 'arm' basophil
75 ing the recall response by CD27(+) IgG class-switched human memory B cells, total IgG secreted is a f
77 irment in production of immunoglobulin class-switched antibodies, which is possibly contributed to by
78 rexpressing MiR-210 exhibited impaired class-switched Ab responses, a finding confirmed in wild-type
79 at Sox2 may regulate AID expression in class-switched B cells to suppress genomic instability associa
81 ciated with a significant reduction in class-switched IgG, and anti-nucleosomal IgG-secreting B cells
82 ic failure and the severe reduction in class-switched memory B cells, while gathering longitudinal la
83 2 anti-parasite mechanisms, including class-switched antibodies, activated leukocytes and innate def
84 assumes multiple cell fates, including class-switched B cells, antibody-secreting plasma cells, and m
85 om infants who survived RSV infection, class-switched antiviral and antinucleosomal antibodies were d
87 to promote B cell differentiation into class-switched plasmablasts and led to downregulation of chemo
88 tiation of WASp-deficient B cells into class-switched plasmablasts in vitro, suggesting that WASp-dep
92 Ab formation, decreases production of class-switched Abs targeting nonnuclear Ags, and limits system
93 1), are critical for the generation of class-switched and hypermutated (mature) Ab and autoantibody r
95 magglutinin leads to the production of class-switched anti-MOG antibodies, dependent on the presence
96 ponse that increases the generation of class-switched antibodies and the frequency of somatic hypermu
97 the events that lead to production of class-switched antibodies during T. gondii infection have not
101 ter reaction and for the production of class-switched antibodies in response to thymus-independent an
103 s naive B cells, higher frequencies of class-switched antibodies were detected in cocultures of CXCR5
105 licular CD4 T cells, and production of class-switched antibody, together with expansion of B1 B cells
106 c infections through the generation of class-switched antibody-secreting cells (ASCs) in germinal cen
108 I compound AZD8055 increased titers of class-switched high-affinity antibodies to a hapten-protein co
110 ro and produced high concentrations of class-switched IgG2b and IgG2c, including anti-RNA antibodies.
111 e observed reductions in expression of class-switched isotypes in OCA-B-/- mice may be due in part to
113 lymphopenia, decreased frequencies of class-switched memory B cells and hypogammaglobulinemia due to
114 er of iNKT cells and the percentage of class-switched memory B cells and propensity to lymphoprolifer
115 us toxin, whereas the proliferation of class-switched memory B cells is suppressed by Stichodactyla h
116 controls revealed that frequencies of class-switched memory B cells were increased in the patients,
118 nal center and ensure replenishment of class-switched memory CD27(+) B cells from Ag-experienced prec
123 es the T cell-dependent development of class-switched, autoreactive memory B cells and plasma cells/p
124 diseases are marked by the presence of class-switched, high-affinity autoantibodies with pathogenic p
125 ith B cells but lacking secreted Ab or class-switched Ab had little deficiency in resistance to Salmo
128 munoglobulin were activated, producing class-switched autoantibody in vivo despite the apparently nor
135 o those patients with severely reduced class-switched memory B cells and an elevated level of CD21(lo
136 ted with recurrent infections, reduced class-switched memory B cells, and hypogammaglobulinemia.
137 D8alpha(-) DCs in mice leads to robust class-switched antibody (Ab) responses to a T cell-dependent (
138 cripts, and reduced titers of secreted class-switched IgG1, IgG3, and IgA antibodies, without alterat
141 n reported to produce antigen-specific class-switched human antibodies, with some demonstrating neutr
142 ell as increased levels of Ag-specific class-switched Ig production following immunization with OVA t
143 sequencing of the BCR from E2-specific class-switched memory B cells sorted from two independent part
146 oproliferative disease (XLP) lack such class-switched memory B cells but are highly susceptible to EB
148 In this study, we showed that the class-switched IgG autoantibody response in MRL/Fas(lpr/lpr) a
149 /CDR3 sequences from those seen in the class-switched response to oxazolone that we have also analyze
152 production of Ag-specific IgM, whereas class-switched isotypes are decreased by approximately 80-90%
153 surface models to derive the electric-field-switched low-symmetry structures of new TTF- and PMDI-ba
154 rrelation (HETCOR) experiment with frequency-switched Lee-Goldburg (FSLG) irradiation is performed on
155 enon of passively Q-switched ~3 mum and gain-switched ~2 mum pulses in a shared cavity was demonstrat
157 erstanding of the origin and fate of the IgE-switched B cell has been markedly improved by studies in
163 st immune responses, T helper type 1 isotype-switched antibodies, and gamma interferon (IFN-gamma)-se
164 plasma cells secreting high-affinity isotype-switched Abs in mice immunized with T cell-dependent Ags
165 te the development of high-affinity, isotype-switched Abs, and immunological memory; consequently, ma
167 e dominant pathway of high-affinity, isotype-switched autoantibody production in the MRL/MpJ-Fas(lpr)
168 uction of high-titer, high-affinity, isotype-switched IgG autoantibodies directed against nucleic aci
170 noclonal antibody (MAb) 9d8 (2a), an isotype-switched variant of the immunoglobulin G3 (IgG3) MAb 9d8
171 major IgMD-expressing subsets and an isotype-switched variant, each developing from distinct B-cell p
173 and B220(+) lymphocytes, IgM(+) and isotype-switched IgG(+) and IgA(+) B cells, antigen presenting c
174 CPS is able to induce potent IgM and isotype-switched IgGs in mice and pigs, yielding functional acti
175 rminal center B cells, more antibody isotype-switched germinal center B cells, more memory B cells, a
177 d by CD138(-) IgD(-) IgM(+) B cells, isotype-switched CD138(-) IgD(-) IgM(-) memory B cells (B(mem)),
179 ulation of memory B cells containing isotype-switched (IgG and IgA) and IgM-only cells and lacking ex
180 We propose that germline-encoded, isotype-switched B cells in newborn piglets differentiate to Ab-
184 We have found a unique role for isotype-switched antibodies in promoting helminth-induced basoph
186 e earliest Ag-driven events in human isotype-switched, IgG-expressing MBCs and compare them with thos
187 ansfer of variable region-identical, isotype-switched, LPS-specific, murine immunoglobulin M (IgM) an
189 as not affected by the deficiency in isotype-switched antibodies, suggesting a direct effect on basop
191 onses, we found a marked decrease in isotype-switched, A. fumigatus-specific antibodies in sera of mi
192 F59 was highly effective in inducing isotype-switched IgG antibodies and long-term protective immune
195 ignant tumor of somatically mutated, isotype-switched plasma cells (PC), usually arises from a common
196 First, we examined circulating non-isotype-switched (IgD(+)CD27(+)) memory cells, a population that
198 notypes characteristic of naive, non-isotype-switched, memory (Bmem) cells and antibody-secreting cel
199 imately, the quality and quantity of isotype-switched Abs produced in Icos(-/-) mice declined over ti
200 abaudi AS infection or production of isotype-switched Abs, but it is necessary for maintenance of a s
204 ggesting that defective apoptosis of isotype-switched autoreactive B cells is central to Fas mutation
206 intained in two different subsets of isotype-switched B cells, germinal center and memory B cells.
209 out and we also raise the subject of isotype-switched CLL, which, despite its rarity, contributes int
211 etected only very low frequencies of isotype-switched IgG-secreting cells in mouse spleens, until at
212 body sequences by deep sequencing of isotype-switched memory B cells or in IgG antibodies elicited ag
213 equired to inhibit the production of isotype-switched pathogenic Abs and the evolution of joint infla
215 A (miR)-155 for normal production of isotype-switched, high-affinity antibodies and for a memory resp
217 fferentiated directly into IgM(+) or isotype-switched (sw) Ig(+) memory B cells in a GC-independent f
219 dent antigens, eliciting protective, isotype-switched antibodies in the absence of conventional TCR a
220 nd to be highly effective in raising isotype-switched IgG antibodies to a T-dependent influenza virus
221 Cs) are long-lived sources of rapid, isotype-switched secondary antibody-forming cell (AFC) responses
223 rminal center (GC) B cell reactions, isotype-switched Ab responses, parasite control, and host surviv
226 DCs was dependent on virus-specific, isotype-switched antibodies (Abs) that facilitated the capture a
227 ayed accumulation of virus-specific, isotype-switched ASC requires CD19-dependent GC formation in CLN
231 -TT conjugate vaccine conform to the isotype-switched (IgG(+)CD27(+)) rather than the IgM memory (IgM
233 ells ranging from early-activated to isotype-switched differentiation stages is both temporally and s
234 nstrated a steady ratio of IgM(+) to isotype-switched GC B cells and a persistent population of GC B
235 tumors are rare variants of typical isotype-switched multiple myeloma with a similar disease outcome
238 ardtii has been shown to be a directly light-switched cation-selective ion channel, which employs 11-
241 +)CD27(+) cells (commonly referred to as non-switched memory) in infected cord blood cell cultures, a
244 alatal/lingual implant position; 2) platform-switched abutments; 3) flapless approach; 4) bone grafts
245 hic bone changes around customized, platform-switched abutments placed according to the "one-abutment
247 ral blood mononuclear cells (PBMCs) with PLY-switched strains and assessed dendritic cell and CD4(+)
249 We particularly show that electrically pre-switched devices in low-resistive states comprise reduce
252 hly focused nanosecond laser pulses from a Q-switched Nd:YAG laser at lambda = 532 nm to generate cav
256 ied by modulating the magnetization, and a Q-switched pulse output with a pulse width of 5 ns and pea
258 eveloped a photoacoustic probe that uses a Q-switched, frequency-doubled Nd:YAG (neodymium, yttrium,
259 produced using a single laser pulse from a Q-switched, frequency-quadrupled Nd:YAG laser that was mod
264 e of an inexpensive, small, and "turn-key" Q-switched 532-nm Nd:YAG laser as a source for nonlinear,
265 (Yb) and an erbium (Er)-doped fiber laser Q-switched by a solution processed, optically uniform, few
266 e picosecond laser, Q-switched ruby laser, Q-switched alexandrite laser, or Q-switched 1064-nm Nd:YAG
267 with 755-nm alexandrite picosecond laser, Q-switched ruby laser, Q-switched alexandrite laser, or Q-
268 t repetition rate achieved so far in a LGS Q-switched laser and it can provide a practical Q-switched
269 lifetime as the gain medium, a stable LGS Q-switched laser was designed with average output power of
270 A 10-mm cavity length magnetooptically Q-switched Nd:GdVO4 laser was demonstrated using a single-
272 ees well with the experiments of passively Q-switched lasers using Ti3 CN at wavelengths of 1558 and
274 techniques, a new phenomenon of passively Q-switched ~3 mum and gain-switched ~2 mum pulses in a sha
275 tched laser and it can provide a practical Q-switched laser with a tunable high repetition rates for
277 is LRD technique utilizes an Er:YAG rotary Q-switched laser with an output wavelength of lambda = 2.9
278 ed laser cavities, we obtain self-starting Q-switched pulses with microsecond duration and kilohertz
279 al-band fiber ring laser with synchronized Q-switched pulses at wavelengths of 1480 nm and 1840 nm, a
280 he most extensively studied device was the Q-switched Nd:YAG laser, which has shown promising results
281 ecorded in the range of 200-975nm by using Q-switched Nd:YAG laser at 532nm (4ns, 10Hz) attached to e
284 l and functional characterization of subtype-switched Epa1 variants shows that specificity is governe
285 ncreased frequency of CD19+IgD+CD27+ unclass-switched memory B cells and a low frequency of somatic m
WebLSDに未収録の専門用語(用法)は "新規対訳" から投稿できます。