ライフサイエンスコーパス: 1,3-butadiene

1 ce exposed to a model DNA-damaging chemical, 1,3-butadiene.

2 requires consideration of both conformers of 1,3-butadiene.

3 radical or via cyano radicals reacting with 1,3-butadiene.

4 with classical double bonds of a 2,3-disila-1,3-butadiene.

5 7-99%) with no ene product from 2,3-dimethyl-1,3-butadiene.

6 ylation of terminal alkenes and 2,3-dimethyl-1,3-butadiene.

7 sence of a radical trap such as 2,3-dimethyl-1,3-butadiene.

8 putative ultimate carcinogenic metabolite of 1,3-butadiene.

9 hyde, trapped in 80% yield with 2,3-dimethyl-1,3-butadiene.

10 o-5-methoxybenzoquinone (14) and substituted 1,3-butadienes.

11 nes to afford predominantly (E,E)-1,4-diaryl-1,3-butadienes.

12 Dehydrohalogenation gives 2-alkyl-1,3-butadienes.

13 Diels-Alder cycloaddition of s-trans-1,3-butadiene (1) should yield trans-cyclohexene (7), ju

14 zyl radical, benzylallenyl radical, 1-phenyl-1,3-butadiene, 1,2-dihydronaphthalene, and naphthalene),

15 Exchange of toluene for anisole, 1,3-butadiene, 1,3-cyclohexadiene, thiophenes, pyrroles,

16 s for the isotopomeric species produced from 1,3-butadiene-1,1,4,4-d(4) dissociation.

17 tail, further studies were carried out using 1,3-butadiene-1,1,4,4-d(4).

18 der adducts of p-methoxycarbonylbenzyl trans-1,3-butadiene-1-carbamate and N,N-dimethylacrylamide hav

19 nthesized from (Z,Z)-1,4-bis(tert-butylthio)-1,3-butadiene (2) to evaluate the effects of electron-wi

20 yloxy-tert-butyldimethylsilane, (E)-1-phenyl-1,3-butadiene, 2,3-dihydrofuran, and 2,5-dihydrofuran) p

21 benzyloxy-3Z,5E-hexadienoyl)- 1-aza-2-ethoxy-1,3-butadiene (40) undergoes cycloaddition to produce as

22 s, such as 1-methoxybutadiene (6g) and alkyl 1,3-butadienes (6a, 6j), the diamination is first-order

23 ) generated polymer-bound 2-(phenylsulfonyl)-1,3-butadiene (9) in situ which underwent Diels--Alder c

24 Reaction of 1 with 2,3-dimethyl-1,3-butadiene afforded the compound [Ar*GaCH(2)C(Me)C(Me

25 catalysts for the selective hydrogenation of 1,3-butadiene,, an industrially important reaction.

26 ween 2 equiv of (E,E)-1,4-bis(4-bromophenyl)-1,3-butadiene and 1,4-benzoquinone led to the formation

27 artially deuterated counterparts (1,1,4,4-D4-1,3-butadiene and 2,3-D2-1,3-butadiene) at two collision

28 ry studies of the photochemistry of 1-phenyl-1,3-butadiene and 4-phenyl-1-butyne.

29 -Alder cycloaddition, which occurs between a 1,3-butadiene and an alkene.

30 bonyls, and C1-C8 hydrocarbons (particularly 1,3-butadiene and benzene) were determined.

31 tly, a new reaction between 2-nitroperchloro-1,3-butadiene and electron-deficient anilines producing

32 rylhydrazine, starting from 2-nitroperchloro-1,3-butadiene and para-nitro aniline, and generated the

33 der reactions of 1-methoxy-4-trimethylsiloxy-1,3-butadiene and the corresponding o-xylylene with acry

34 ted a(3)Pi(u) state have been conducted with 1,3-butadiene and two partially deuterated counterparts

35 s-Alder (DA) reactions of phosphaethene with 1,3-butadiene and with isoprene reveal asynchronous tran

36 aque development: the vapor phase component, 1,3 butadiene, and the tar component, the tobacco-specif

37 toxins acrolein; acrylamide; acrylonitrile; 1,3-butadiene; and ethylene oxide) than combustible ciga

38 However, 1,3-butadienes are also formed in the case of ortho-subs

39 dienes, the 1-(2-oxazolidinon-3-yl)-3-siloxy-1,3-butadienes are still very reactive in Diels-Alder re

40 alkenes (ethylene, propylene, 1-butene, and 1,3-butadiene) are investigated by experiments and densi

41 The photodissociation dynamics of 1,3-butadiene at 193 nm have been investigated with phot

42 allyl cyanide, 1-octene, and trans-1-phenyl-1,3-butadiene at low temperatures and pressures with pas

43 erparts (1,1,4,4-D4-1,3-butadiene and 2,3-D2-1,3-butadiene) at two collision energies of 12.7 and 33.

44 1,3-Butadiene (BD) is an important industrial and enviro

45 1,3-Butadiene (BD) is an important industrial chemical a

46 P2 efficiently to 1,3-cyclohexadiene (CHD), 1,3-butadiene (BD), and (C2H4)Pt(PPh3)2 to form P2(CHD)2

47 -shift), closure to trialene (bicyclo[1.1.0]-1,3-butadiene), bond-shift isomerization to exchange C-2

48 omers of DEB are produced metabolically from 1,3-butadiene, but S,S-DEB is the most cytotoxic and gen

49 exoergic reaction of the ethynyl radical and 1,3-butadiene, C(2)H + H(2)CCHCHCH(2) --> C(6)H(6) + H,

50 icon-bearing radical, silylidyne (SiH), with 1,3-butadiene (C4 H6 ) in the gas phase under single-col

51 is(2,6-dialkylphenyl)-1,4-diaza-2,3-dimethyl-1,3-butadiene) carrying nearly unperturbed nitric oxide

52 The abatement of 9 polychloro-1,3-butadienes (CBDs) in aqueous solution by ozone, UV-C

53 A 1,4-diamino-2,3-disila-1,3-butadiene derivative of composition (Me2-cAAC)2(Si2C

54 odular and atom-efficient synthesis of 2-aza-1,3-butadiene derivatives has been developed via nickel-

55 1G* of selected dilithium derivatives of the 1,3-butadiene dianion including cis-dilithio-1,4-bis(TMS

56 o)-1,1'-binaphtyl (BINAP) or 1,4-diphosphino-1,3-butadiene (dpb).

57 r reactions, somewhat more than 1,3-dialkoxy-1, 3-butadienes (e.g., Danishefsky's diene).

58 mational equilibria of 10 methyl-substituted 1,3-butadienes [(E)- and (Z)-1,3-pentadiene; 2-methyl-1,

59 ienes [(E)- and (Z)-1,3-pentadiene; 2-methyl-1,3-butadiene; (E)-2-methyl-1,3-pentadiene; 2,3-dimethyl

60 e; (E)-2-methyl-1,3-pentadiene; 2,3-dimethyl-1,3-butadiene; (E,E)-, (E,Z)-, and (Z,Z)-2,4-hexadiene;

61 , isobutane, propylene, 2-methylpropene, and 1,3-butadiene even xenon are coencapsulated with other g

62 aptable to molecular epidemiology studies on 1,3-butadiene-exposed workers.

63 ed in mice treated with 3, 62.5, or 1250 ppm 1,3-butadiene for 10 days and rats exposed to 3 or 62.5

64 or 10 days and rats exposed to 3 or 62.5 ppm 1,3-butadiene for 10 days, or to 1000 ppm 1,3-butadiene

65 pm 1,3-butadiene for 10 days, or to 1000 ppm 1,3-butadiene for 90 days, using a newly developed immun

66 exhibited three phases of isoprene (2-methyl-1, 3-butadiene) formation, corresponding to (i) glucose

67 In this context, on-purpose production of 1,3-butadiene from biomass-derived feedstock is an inter

68 ission of the hydrocarbon isoprene (2-methyl-1,3-butadiene) from many C3 plants.

69 cid ethyl ester with 2,3-bis(phenylsulfonyl)-1,3-butadiene gives rise to a 7-oxa-1-azanorbornane cycl

70 2-Dimethylphenylsilyl-1,3-butadiene has also been prepared from chloroprene on

71 1.0]but-2-ylmethanols (endo- and exo-9) from 1,3-butadiene has been developed.

72 2-Triethoxysilyl-substituted 1,3-butadiene has been prepared in 30-g quantities from

73 ried out in a 4.4 M solution of 2,3-dimethyl-1,3-butadiene in CH2Cl2.

74 luded; experiments with partially deuterated 1,3-butadiene indicate the formation of the thermodynami

75 ice, a strain that acquired higher levels of 1,3-butadiene-induced DNA damage, around the same genes,

76 AST/EiJ mice, which acquired relatively less 1,3-butadiene-induced DNA damage, we observed increased

77 1,3-Butadiene is an important industrial chemical used i

78 droxyflavones with trans, trans-1,4-diphenyl-1,3-butadiene is described.

79 surement of styrene, ethylene, 1-octene, and 1,3-butadiene is illustrated.

80 1,3-Butadiene is metabolized to several epoxides that fo

81 Together, these data show that 1,3-butadiene is primarily metabolized via the 3-butene-

82 A two-step procedure for preparing 2-alkyl-1,3-butadienes is described.

83 ric Diels-Alder reaction of N-sulfonyl-1-aza-1,3-butadienes is reported enlisting a series of 19 enol

84 Approximately 500 Tg of 2-methyl-1,3-butadiene (isoprene) is emitted by deciduous trees e

85 (X(1) Sigmag (+) , a(3) Piu ), with 2-methyl-1,3-butadiene (isoprene; C5 H8 ; X(1) A') accessing the

86 ght into species and exposure differences in 1,3-butadiene metabolism.

87 The analyses of several adducts derived from 1,3-butadiene metabolites provided new insight into spec

88 ining N(2)-guanine adducts of stereoisomeric 1,3-butadiene metabolites.

89 he carbon-carbon double bond of the 2-methyl-1,3-butadiene molecule.

90 actions of ethynyl radicals with substituted 1,3-butadiene molecules.

91 ed through reaction of pyridyl radicals with 1,3-butadiene or sequentially with two acetylene molecul

92 odds ratio (OR) = 2.30; 95% CI: 1.44, 3.67], 1,3-butadiene (OR = 2.23; 95% CI: 1.28, 3.88), benzene,

93 lorobenzene (OR = 3.27; 95% CI: 1.17, 9.14), 1,3-butadiene (OR = 3.15; 95% CI: 1.57, 6.32), and benze

94 monitoring data, concentrations of benzene, 1,3-butadiene, perchloroethylene, and hexavalent chromiu

95 .2.2]octa-2,5-diene, and benzobarrelene with 1,3-butadienes proceed in excellent yields using cobalt-

96 ability of the substituent to stabilize the 1,3-butadiene radical cation by electron donation or con

97 of the (E) and (Z) isomers of the resulting 1,3-butadiene radical cations depends largely on steric

98 lecules (C(2)) with C(4)H(6) isomers such as 1,3-butadiene represent a potential, but hitherto unnoti

99 10 with cyclohexa-1,3-diene and 2,3-dimethyl-1,3-butadiene (several cycloadducts characterized by X-r

100 arbon atoms are attached to C2 and C3 of the 1,3-butadiene tether.

101 is(pentafluorophenyl)-2,3-dimethyl-1,4-diaza-1,3-butadiene; TFA = trifluoroacetate] has been reported

102 is(pentafluorophenyl)-2,3-dimethyl-1,4-diaza-1,3-butadiene; TFA is trifluoroacetate] converts benzene

103 arbon to one of the terminal carbon atoms of 1,3-butadiene, the collision complex undergoes trans-cis

104 d to the reaction of 1,1-difluoroallene with 1,3-butadiene, the results of which indicate that the us

105 For trans-1-phenyl-1,3-butadiene, the stable alkyl complex is an eta(3)-all

106 To specifically examine metabolism of 1,3-butadiene to 1,2;3,4-diepoxybutane, the formation of

107 d 1,4-addition across the commodity chemical 1,3-butadiene to afford skipped polyene products is repo

108 combination of H2C horizontal lineNH and cis-1,3-butadiene to form a six-membered ring was examined b

109 e (9) regioselectively reacts with 1-methoxy-1,3-butadiene to provide cycloadduct 16.

110 tion of 1,4-, 1,3-, and 2,3-bis(2-nitroaryl)-1,3-butadienes to afford 2,2'-, 2,3'-, and 3,3'-biindole

111 eaves of many plants emit isoprene (2-methyl-1,3-butadiene) to the atmosphere, a process which has im

112 nyl]benzenes were prepared from 2,3-dimethyl-1,3-butadiene using Diels-Alder cycloadditions and Pd(0)

113 ldehydes and ketones, furans, acrylonitrile, 1,3-butadiene, vinyl chloride, and nitromethane) in the

114 Additionally, 1,3-dipyrrolidino-1,3-butadiene was shown to be significantly more reactiv

115 Acrolein, furan, acrylonitrile, and 1,3-butadiene were considered to be the most harmful VOC

116 ative syntheses of several 2,3-disubstituted 1,3-butadienes were achieved.

117 l group nonbonded interactions in conjugated 1,3-butadienes were delineated.

118 and chiral 1-(2-oxazolidinon-3-yl)-3-siloxy-1,3-butadienes were prepared from readily available star

119 was similar in mice exposed to 3 or 62.5 ppm 1,3-butadiene, whereas 2-hydroxy-3-butenyl-valine was 3-

120 selective, while 1-methoxy-4-trimethylsiloxy-1,3-butadiene will give a small preference ( approximate

121 in solution in the presence of 2,3-dimethyl-1,3-butadiene with a quantum efficiency of approximately

122 For the reaction of 2,3-dimethyl-1,3-butadiene with acrylonitrile, the concerted reaction

123 lar cycloaddition of 2,3-bis(phenylsulfonyl)-1,3-butadiene with an appropriate oxime.

124 s a solid catalyst for the polymerization of 1,3-butadiene with high stereoselectivity (>99% 1,4-cis)

125 the volatile hydrocarbon isoprene (2-methyl-1,3-butadiene), with subsequent analysis of isoprene by

126 4-decylaniline and the volatile 2,3-dimethyl-1,3-butadiene, with an outlier being operationally defin