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1 lase) and sterol 12alpha-hydroxylase/CYP8B1 (12alpha-hydroxylase).
2 ceptor, oxysterol 7alpha-hydroxylase, sterol-12alpha-hydroxylase, and hepatic bile acid transporters
4 esterol 7alpha-hydroxylase (Cyp 7a1), sterol 12alpha-hydroxylase (Cyp 8b1), and the intestinal bile a
6 effects of the level of expression of sterol 12alpha-hydroxylase (CYP8b1) and cholesterol 7alpha-hydr
9 terol 7alpha-hydroxylase (Cyp7a1) and sterol 12alpha-hydroxylase (Cyp8b1) partly through inducing sma
10 d bile acid homeostasis, notably cholesterol 12alpha-hydroxylase (CYP8B1), which was strongly reexpre
13 chain fatty acids-like 3, Elovl3 and sterol 12alpha-hydroxylase, Cyp8b1, by enhancing their expressi
18 on times still resulted in lower 7alpha- and 12alpha-hydroxylase expression, but unchanged SHP expres
25 10-fold lower expression of the 7alpha- and 12alpha-hydroxylase genes and up to 8-fold higher SHP ex
26 This higher expression of the 7alpha- and 12alpha-hydroxylase genes resulted in a 33% higher bile
27 heterozygous FTF knockout mice, 7alpha- and 12alpha-hydroxylase genes were expressed at 5-7-fold hig
28 n transcription factor (FTF) is required for 12alpha-hydroxylase promoter activity and bile acid-medi
29 DNA elements that are required for both the 12alpha-hydroxylase promoter activity and bile acid-medi
30 NF-4 is the factor involved in regulation of 12alpha-hydroxylase promoter activity by bile acids thro
31 e short heterodimer partner (SHP) suppresses 12alpha-hydroxylase promoter activity via an interaction
35 ear factor-4 (HNF-4) binds and activates the 12alpha-hydroxylase promoter and is required for 12alpha
39 the C-36-mediated regulation of 7alpha- and 12alpha-hydroxylase promoters mapped to the alpha1-fetop
40 NF-4 recognition site within the 7alpha- and 12alpha-hydroxylase promoters, which can otherwise be oc
41 nzymes is sterol 12alpha-hydroxylase/CYP8B1 (12alpha-hydroxylase), the specific enzyme required for c
42 on factor (FTF) are activators of 7alpha-and 12alpha-hydroxylase transcription and that the small het
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