ライフサイエンスコーパス: 13C

1 13C and 15N MAS spectra of both nanocrystals and fibrils

2 13C detected 2D 13C-13C spectroscopy is performed in the

3 13C flux analysis studies have become an essential compo

4 13C isotropic chemical shifts and backbone (phi, psi) to

5 13C labeling has been shown to greatly minimize matrix e

6 13C labeling studies performed in G. sulfurreducens indi

7 13C metabolic flux analysis (13C-MFA) has been widely us

8 13C NMR and stopped-flow kinetic experiments reveal that

9 13C relaxivity in C60 induced by nitroxide has also been

10 13C steady-state metabolic flux analysis showed that oxi

11 13C-13C Spin-spin coupling constants (JCC) have been mea

12 13C-Based metabolic flux analysis provides valuable info

13 13C-Glucose was dissolved in the test meal and 13CO2 det

14 13C-Isotopologue compositions of amino acids from bacter

15 sotope effects (AKIEs) of 1.0070 +/- 0.0002 (13C-AKIE, oxidation), 1.068 +/- 0.001 (13C-AKIE, S(N)2),

16 0002 (13C-AKIE, oxidation), 1.068 +/- 0.001 (13C-AKIE, S(N)2), and 1.0087 +/- 0.0002 (37Cl-AKIE, S(N)

17 amines directly in aqueous medium with 1,1'-13C(2) acetic anhydride is a simple method that creates

18 isotopic enrichment is higher than 99% for 1-13C (Phe), 2-2H (Phe), and 3,4-15N2 (cytidine), 93% for

19 ization of approximately 20% in seconds in 1-13C-succinic-d2 acid.

20 m the (13)C incorporation from of infused [1-13C] glucose into glutamate [4-13C] relative to alanine

21 S, SPS, respectively) by incorporation of [1-13C]proline (using gas chromatography-mass spectrometry)

22 intermediates formed with the substrates, [1-13C]ethanolamine, [2-13C]ethanolamine, and unlabeled eth

23 e and exchange interactions as well as the 1-13C hyperfine splitting tensor were analyzed via spectra

24 the molecular addition of parahydrogen to 1-13C-fumaric acid-d2 and the subsequent transfer of spin

25 Feeding experiments using (1-13C)Glc followed by analysis of labeling patterns by 13C

26 ps were performed on separate days, using [1-13C]glucose infusion to increase plasma 13C enrichment.

27 g in EPR spectra of samples prepared with [1-13C]ethanolamine and the absence of such splitting in sp

28 ning, leveraging data from approximately 100 13C-MFA papers on heterotrophic bacterial metabolisms.

29 Approximately 100% 13C-labeled graphite was made and converted to 13C-label

30 r correlation experiments involving 1H, 11B, 13C, 19F, 29Si, and 31P nuclei.

31 A large 12C/13C (k(12C)/k(13C)) isotope effect of approximately equa

32 n of cyclohexenone, while a much smaller 12C/13C isotope effect of 1.010 was observed at the C2 (alph

33 Carbon-13 (13C) solid-state nuclear magnetic resonance (SSNMR) spec

34 in-spin couplings 13Calpha-1Halpha, 13Calpha-13C', 15N-13C', and 15N-1HNu.

35 uplings 13Calpha-1Halpha, 13Calpha-13C', 15N-13C', and 15N-1HNu.

36 equence and exploiting differences in 1J 15N-13C coupling patterns to filter selected 15N resonances

37 Two-dimensional 13C-13C and 15N-13C solid state NMR spectra of a uniformly 15N- and 13C-

38 ed at specific sites and two-dimensional 15N-13C and 13C-13C NMR spectra of samples that are uniforml

39 that allowed only the fungus access to a 15N/13C-labeled organic patch; in some cases, one plant was

40 The experiments are applied to 15N/13C/2H/[Leu,Val]-methyl-protonated IIBMannose, a protein

41 o acids in the B chain were labeled with 15N/13C.

42 ide chain, including isotope reporters (19F, 13C) that can be used in biophysical experiments such as

43 1H, 13C, and 15N resonance assignments revealed very similar

44 region of two-dimensional heteronuclear 1H, 13C NMR spectra of natural organic matter and related ma

45 ches the data reported for neopeltolide (1H, 13C, HRMS, IR, NOESY, [alpha]), thereby establishing the

46 mbines the experimental determination of 1H, 13C, and 15N chemical shifts by magic-angle spinning (MA

47 conductor nanocrystals was studied using 1H, 13C, and 31P NMR spectroscopy and mass spectrometry.

48 1H-13C correlations of target analytes at < or = 25 microg/

49 n example we measured a natural abundance 1H-13C HSQC spectrum of metabolites from granulocyte cell e

50 oved to be superior for detecting analyte 1H-13C correlations.

51 Two-dimensional 1H-13C HSQC (heteronuclear single quantum correlation) and

52 es, we have recorded ultrahigh-resolution 1H-13C HSQC NMR spectra of cell extracts, which exhibit spe

53 allows recording of ultrahigh resolution 1H-13C HSQC spectra in a fraction of the time needed for re

54 We show that a high-resolution 1H-13C HSQC spectrum with 4k complex increments recorded li

55 the hydroxyphenyl ring determined by the 1H-13C DIPSHIFT experiment indicate that the bond between t

56 ned in the medium and cell extract using 1H-{13C}-NMR.

57 The subjects were administered [2-13C]acetate for 2 hours and scanned throughout that time

58 with the substrates, [1-13C]ethanolamine, [2-13C]ethanolamine, and unlabeled ethanolamine were acquir

59 ability and fractional absorption of R-(+)[2-13C]equol were higher than those of S-(-)[2-13C]equol or

60 The pharmacokinetics of racemic (+/-)[2-13C]equol were different from those of the individual en

61 -13C]equol were higher than those of S-(-)[2-13C]equol or the racemate.

62 tting in spectra of samples prepared with [2-13C]ethanolamine show that the unpaired electron is loca

63 13C detected 2D 13C-13C spectroscopy is performed in the usual manner.

64 temperature-jump methods to develop a new 2D 13C-13C NMR experiment that yields a factor of 100-170 i

65 Detection using either 1D or 2D 13C NMR experiments produces highly resolved spectra wit

66 In this study, 1H, 2H, 13C, 15N NMR and liquid/liquid intermolecular transfer d

67 tivity, the presence of isotopic excess (2H, 13C, 15N, 18O) is readily determined within 1%.

68 bisphosphonate drugs to human bone using 2H, 13C, 15N, and 31P nuclear magnetic resonance spectroscop

69 present, Envelope supports labeling with 2H, 13C, and 15N, and supports adjustments for baseline corr

70 nto glutamate [4-13C] relative to alanine [3-13C] assessed by LC-tandem MS in muscle biopsies.

71 Analysis of the 5J(HH) and 3J(13C-H) coupling constants in the NMR spectra showed an a

72 of infused [1-13C] glucose into glutamate [4-13C] relative to alanine [3-13C] assessed by LC-tandem M

73 [6-13C], [6-15N], and [1-15N]adenosines reported intrinsic

74 Adenines labeled at [6-13C], [6-15N], [6-13C, 6-15N], and [1-15N] were synthesized and enzymatica

75 Adenines labeled at [6-13C], [6-15N], [6-13C, 6-15N], and [1-15N] were synthesi

76 PurE (AaPurE) and the active site ligand [6-13C]citrate probed a single ionization equilibrium assoc

77 of BACUS to the structure determination of a 13C unenriched protein for which no prior experimental 3

78 sign strategy that entails introduction of a 13C-atom (*) at specific sites of the porphyrins where t

79 alues when multiple protons are coupled to a 13C nucleus.

80 Using a 13C-labeled inhibitor, NMR analysis of the 1-flavin conj

81 (SSNMR) spectra of GO for natural abundance 13C have poor signal-to-noise ratios.

82 In these 2D experiments, natural abundance 13C was observed from bicelles containing DMPC and DHPC

83 Accordingly, 13C-labeled glutamine was incorporated into 2HG in cells

84 nhanced nuclear alignment) method to achieve 13C polarization of approximately 20% in seconds in 1-13

85 ltransferase (ST6Gal-I) to enzymatically add 13C-N-acetylneuraminic acid (NeuAc or sialic acid) to gl

86 ntration (cumulative percent of administered 13C dose recovered) in expiratory breath samples taken a

87 led by NMR coupling constants between alkyne 13C and 1H nuclei as well as between alkyne 13C and pyri

88 13C and 1H nuclei as well as between alkyne 13C and pyridine 15N (2hJCN).

89 e found through 13C Metabolic Flux Analysis (13C MFA) for central carbon metabolism but, additionally

90 ellular fluxes, 13C Metabolic Flux Analysis (13C MFA), uses the labeling pattern obtained from metabo

91 uring fluxes by 13C metabolic flux analysis (13C-MFA) has become a key activity in chemical and pharm

92 13C metabolic flux analysis (13C-MFA) has been widely used to measure in vivo enzyme

93 ecific sites and two-dimensional 15N-13C and 13C-13C NMR spectra of samples that are uniformly 15N- a

94 y with 15N, species B uniformly with 15N and 13C, and species C uniformly with 15N but selectively wi

95 nd RNA with the NMR-active isotopes, 15N and 13C, opened the door to detailed analyses of macromolecu

96 was achieved by low-temperature 1H, 15N, and 13C NMR from FSO3H-SbF5-SO2ClF solutions.

97 timized experiment correlating 1HN, 15N, and 13C' resonances, referred to as c-TROSY-HNCO is presente

98 -15N HSQC spectra were recorded for 15N- and 13C-labeled murine amelogenin as a function of increasin

99 id state NMR spectra of a uniformly 15N- and 13C-labeled sample indicate that a relatively small frac

100 ectra of samples that are uniformly 15N- and 13C-labeled.

101 opy was essentially eliminated, while 1H and 13C chemical shift information could be derived quickly

102 c matter and related materials (e.g., 1H and 13C chemical shifts ranging from approximately 5 to 10 a

103 Specifically, the 1H and 13C NMR assignments are inconsistent with an N-terminal

104 uctural investigations in solution by 1H and 13C NMR clearly showed scalar coupling of fluorine with

105 ons were found at low temperatures by 1H and 13C NMR for both formic acid and an adduct with hexafluo

106 Low-temperature 1H and 13C NMR spectra of formic acid (1) showed separate signa

107 tural elucidation by multidimensional 1H and 13C NMR spectroscopy revealed the accumulated metabolite

108 gnment to 35, undergirded by detailed 1H and 13C NMR studies, is consistent with proper transannular

109 ison of predicted chemical shifts for 1H and 13C with experimental values and with predictions of com

110 31P and 13C NMR studies using isotopically labeled substrates as

111 roups in the 6 position are shown by 6Li and 13C NMR spectroscopic studies to be monomers in THF.

112 xic or hypoxic (120 min only) conditions and 13C enrichment determined in the medium and cell extract

113 in the 1960s between pi-electron density and 13C shifts for classical 4n + 2 (n=0, 1, 2) pi-electron

114 The use of metabolite derivatization and 13C NMR spectroscopy produces data suitable for metaboli

115 the integration of extracellular fluxes and 13C enrichment measurements, HepatoDyn predicted that th

116 ion, with input of the molecular formula and 13C NMR spectrum of the isolated compound.

117 as made and converted to 13C-labeled GO, and 13C SSNMR was used to reveal details of the chemical bon

118 monomer to ligand was confirmed by GC/MS and 13C NMR after quenching.

119 simultaneously because the observed NOEs and 13C(alpha) chemical shifts correspond to a dynamic ensem

120 knot structure, dynamics analyzed by RDC and 13C relaxation measurements, and base pair stability.

121 nt-infusion protocol with [15N]arginine and [13C]- and [2H]citrulline.

122 Plasma and urinary [13C]R-equol and [13C]S-equol concentrations were measured by tandem mass

123 e chemistry was slowed for both [2H]PNP and [13C, 15N]PNP in proportion to their altered protein mass

124 dipole-dipole couplings in samples that are 13C-labeled at specific sites and two-dimensional 15N-13

125 in a form that exploits heteronuclei such as 13C.

126 way as through the standard amino acid based 13C MFA, and quantify the amount of information lost as

127 hemical shift and that of the directly bound 13C or 15N, is subsequently mapped to specific atoms in

128 In vivo brain 13C magnetic resonance spectroscopy was used to measure

129 n of E-1 in this solvent mixture was 4.3% by 13C NMR.

130 sured extracellular fluxes as constrained by 13C labeling data.

131 plex mixture and enhances their detection by 13C NMR.

132 ment of lactate production, as determined by 13C magnetic resonance spectroscopy (MRS) of hyperpolari

133 Measuring fluxes by 13C metabolic flux analysis (13C-MFA) has become a key a

134 ard to both real-time noninvasive imaging by 13C MRS as well as therapeutic response.

135 d maritime Antarctic regions, as informed by 13C and 18O signals in organic material.

136 ne containing peptides that were modified by 13C iodoacetic acid showed a molecular weight that was 2

137 bile sites, most of which can be observed by 13C solid-state NMR even without magic-angle spinning.

138 followed by analysis of labeling patterns by 13C-NMR, confirmed an MVA-dependent biosynthesis; howeve

139 e inhibitor cyanide (CN-) was also probed by 13C NMR.

140 complex, the citrate central carboxylate C6 13C peak moves upfield, indicating diminution of negativ

141 Stable-isotope-labeled carbon (13C) or nitrogen (15N) sources are assimilated into micr

142 ens TC1 (i) delivered highly characteristic (13C/12C, 15N/14N) fractionation trends for pathway ident

143 straints together with observed and computed 13C(alpha) chemical shifts, is applied to determine the

144 Consecutively 13C urea breath tests results were extracted from the fi

145 sites of mechanistic interest also contains 13C at all carbon positions, whereas the 16 O-labeled nu

146 ar couplings, C-H and N-H dipolar couplings, 13C chemical shift anisotropies, and 1H T1rho relaxation

147 ne cysteine of a double-cysteine mutant cTnC(13C/51C) as a FRET donor and attaching DDPM to the other

148 which usually requires a combination of 2-D 13C NMR spectroscopy and GC/MS.

149 are manifested in the temperature-dependent 13C and 15N spectra, 13C-1H and 15N-1H dipolar couplings

150 We describe 13C NMR studies demonstrating a CODH-catalyzed steady-st

151 rect dimensions, while the directly detected 13C' is doubly TROSY-optimized with respect to 1HN and 1

152 Two-dimensional 13C-13C and 15N-13C solid state NMR spectra of a uniform

153 y 3 and 4 times, respectively, versus direct 13C and 15N detection.

154 ar magnitude but opposite sign for the donor 13C and acceptor 15N nuclei.

155 allinity of all salts was documented by DSC, 13C CP-MAS NMR, and XRPD.

156 m metabolites (typically amino acids) during 13C labeling experiments to derive intracellular fluxes.

157 Dynamic 13C labeling experiments indicate the presence of distin

158 or sham operation (sham; n=8) using dynamic 13C-nuclear magnetic resonance.

159 were perfused with buffer containing either 13C-palmitate plus glucose or (13)C glucose plus palmita

160 The high-field 13C multiplets are observed as a function of pH, and the

161 ve method of measuring intracellular fluxes, 13C Metabolic Flux Analysis (13C MFA), uses the labeling

162 to prepare chemically modified graphenes for 13C SSNMR analysis with enhanced sensitivity and for fun

163 The resulting value of R1 for 13C is substantially smaller relative to the 1H relaxati

164 lF2/CHCl2F/(CH3)2O) was larger than that for 13C-labeled methyl formate in the same solvent (0.2%), w

165 From 13C NMR spectroscopy, it was apparent that the C3'-signa

166 lic engineering, that incorporates data from 13C labeling experiments and genome-scale models.

167 The data from 13C labeling experiments provide strong flux constraints

168 ing HepatoDyn to integrate data derived from 13C based experiments.

169 we use NMR distance restraints derived from 13C dipolar recoupling measurements to guide the simulat

170 unassigned distance restraints derived from 13C- and 15N-edited NOESY spectra.

171 hin several amino acid types determined from 13C chemical shifts is consistent with the ligand-free X

172 The 13C line widths measured from 13C-13C 2D chemical shift correlation spectra are approx

173 experimental order parameters obtained from 13C relaxation measurements.

174 here there is a spin-active X-nucleus (e.g., 13C, 15N, 31P) label present.

175 However, shorter tail ADs (G2-15C and G2-13C) and lower generation (G0 and G1) dendrimers failed

176 measurements of R1, R1rho, and heteronuclear 13C{1H} NOEs for protonated base (C2, C5, C6, and C8) an

177 rientation and dynamics of A-form helices in 13C/15N isotopically enriched RNA samples using NMR resi

178 ate the presence of an anionic intermediate, 13C isotope effect studies have been performed using the

179 Measurements of intermolecular 13C-13C dipole-dipole couplings in selectively carbonyl-

180 Using the stable isotope 13C-labeling technique, we analyzed the carbon fluxes th

181 contain synthetically incorporated isotopes (13C, 15N, etc) generating a distinct isotope pattern.

182 Recently, the use of stable isotopes (13C) to trace carbon from specific substrates into micro

183 d (188)Os) and three unique 13C isotopomers (13C in ethylene, axial, and equatorial positions) were o

184 A large 12C/13C (k(12C)/k(13C)) isotope effect of approximately equal to 1.032 was

185 gment following helix E, experiences a large 13C shift corresponding to a conformational change of Il

186 nsion of this approach to accurately measure 13C-31P and 1H-31P couplings from phospholipids, which a

187 The introduction of the meso-13C label provides a "clock" (via the hyperfine interact

188 on, we have performed NMR studies on [methyl-13C]methionine-labeled UvrB from Bacillus caldotenax (mo

189 Critically, the dispersion is at natural 13C abundance; this matches typical pharmaceutical resea

190 spectroscopy of the brain to observe natural 13C abundance of N-acetylaspartate (NAA) and the appeara

191 bed including X-ray crystallography, 1H NMR, 13C NMR, HMQC, UV-visible, HPLC, MALDI-MS, and electroch

192 luble and have been characterized by 1H NMR, 13C NMR, MALDI-TOF, and UV-vis spectroscopy.

193 omposition products, because hyphae were not 13C-enriched.

194 The complex .Cr(13CO)2(O=13C=CHSiMe3)(C5Me5) has been studied by electron spin re

195 ; A(53Cr) = 125 MHz; A(13CO) = 22.5 MHz; A(O=13C=CHSiMe3) = 12.0 MHz.

196 /NF1(333)-catalyzed hydrolysis of [beta18 O3,13C]GTP were determined by change in the isotope ratio o

197 the agreement between predicted and observed 13C(beta) chemical shifts, and some stereochemical quali

198 After addition of 13C or deuterated analogues to a sediment sample, the is

199 -acetylaspartate (NAA) and the appearance of 13C-labeled glutamate, glutamine, and acetate.

200 been derived that allows the calculation of 13C/12C ratios from the whole isotopic distributions, gi

201 scopy was used to measure the time course of 13C label incorporation into different metabolites and t

202 s the 16 O-labeled nucleotide is depleted of 13C.

203 sensitivity, for which inverse detection of 13C and 15N signals with 1H is one promising approach.

204 4-bromostyrene) (PS/P4BrS), the diffusion of 13C-labeled PS has been investigated near the respective

205 the basis of the smaller magnetic moment of 13C.

206 Correlation plots of 13C and 18O values show that species (Chorisodontium aci

207 surements did not fully utilize the power of 13C-MFA.

208 ches can dramatically improve the quality of 13C-MFA results with important applications in metabolic

209 f fluxes using only relative quantitation of 13C-labeled metabolites.

210 on from a protein offer a better sampling of 13C' CSA for different amino acid types in a complex het

211 The site of 13C substitution is at a meso-position, either the site

212 d sensitivity and for fundamental studies of 13C-labeled graphite and graphene.

213 Nuclear magnetic resonance studies of 13C-labeled RH as a function of experimental conditions

214 Here we propose a new type of 13C MFA that infers fluxes based on peptide labeling, in

215 The approach makes use of 13C(alpha) chemical shifts, computed at the density func

216 rms and extends recognition determinants of -13C.

217 rient containing 3-O-methylglucose (3-OMG), [13C]triolein, and [(99m)Tc]sulfur colloid was administer

218 problem can be resolved after more papers on 13C-MFA are published for non-model species.

219 modification by iodoacetic acid with 12C or 13C.

220 onradioactive but NMR-active isotope (15N or 13C).

221 Our 13C- and 1H-chemical exchange saturation transfer (CEST)

222 (13C) = 25.8 +/- 5.1% (when produced) and %P(13C) = 14.2 +/- 0.7% (when imaged), T1 = 74 +/- 3 s), an

223 zed 1-(13)C-succinate-d2 (30 mM in water, %P(13C) = 25.8 +/- 5.1% (when produced) and %P(13C) = 14.2

224 Investigations of dual pathway 13C-13C couplings, 3+3JC1,C4 and 3+3JC2,C5, revealed an

225 directed isotope labeling scheme that places 13C with high efficiency and specificity at the nucleoti

226 g [1-13C]glucose infusion to increase plasma 13C enrichment.

227 Plasma [13C]equol concentration appearance and disappearance cur

228 site chemistry in isotopically labeled PNP (13C, 15N, and 2H).

229 ulse to yield a sample with highly polarized 13C spins.

230 ts is reflected in the carbon isotope ratio (13C/12C) in GTP or GDP, which is determined by the use o

231 re we extend to the protein-bound RNA recent 13C relaxation studies of motions in the RNA recognized

232 on predicted by our model agrees with recent 13C fluxomics experiments, and that our model largely re

233 Resolved 13C hyperfine splitting in EPR spectra of samples prepar

234 d by the experiments of TOCSY, NOESY, ROESY, 13C HSQC 2D NMR, and ESI-MS and GC.

235 cating mutations in vacuolar protein sorting 13C (VPS13C).

236 The residue-specific 13C' CSA tensor principal components, sigma(11), sigma(2

237 However, the analysis of the site-specific 13C IR signals reveals distinct unfolding thermodynamics

238 rared spectroscopy (FTIR) with site-specific 13C isotopic labeling.

239 e temperature-dependent 13C and 15N spectra, 13C-1H and 15N-1H dipolar couplings and 1H rotating-fram

240 onetheless, two-dimensional (2D) solid state 13C-13C NMR spectra of Rev filament and Rev-RNA coassemb

241 A combination of solid-state 13C CPMAS NMR, 2H NMR, X-ray-determined anisotropic disp

242 nance assignment that combines new strategic 13C labeling technologies with filter/edit type NOESY ex

243 affinity column, and addition of synthesized 13C-CMP-NeuAc to the desialylated ST6Gal-I.

244 previously measured by variable-temperature 13C CPMAS NMR and quadrupolar echo 2H NMR line-shape ana

245 We also show that 13C' CSA tensors are sensitive to hydrogen-bond length b

246 The 13C chemical shifts of the primary visual photointermedi

247 The 13C line widths measured from 13C-13C 2D chemical shift

248 The 13C splitting from C1 persists from 10 ms throughout the

249 The 13C' CSA principal components cluster about the average

250 The 13C-enriched ketone substrate, dihydroxyacetone phosphat

251 The 13C=18O isotopic label shifted the carbonyl stretching f

252 relation between experimental shifts and the 13C NMR shifts calculated with density functional theory

253 Changes in the 13C NMR line shapes show that the diphenyl compound 8 un

254 MR and quantum chemical investigation of the 13C gamma NMR chemical shifts in phenylalanine and tyros

255 0 ns), remains fast on the time scale of the 13C hyperfine clock ( approximately 50 ns).

256 The orientation of the principal axes of the 13C hyperfine splitting tensor shows that the long axis

257 The unique IR signature of the 13C=18O label was exploited to probe the equilibrium the

258 The comparisons to the 13C study showed improvement upon inclusion of the corre

259 statics, and other long-range factors to the 13C' CSA tensor.

260 tric emptying of solids was analysed by the [13C]octanoic acid breath test.

261 Subsequently, these 13C-prelabeled amoebae were infected with L. pneumophila

262 Through 13C-labeled isotope labeling experiments we elucidate th

263 ew method are similar to those found through 13C Metabolic Flux Analysis (13C MFA) for central carbon

264 C-labeled graphite was made and converted to 13C-labeled GO, and 13C SSNMR was used to reveal details

265 ling experiments is of central importance to 13C-MFA as it determines the precision with which fluxes

266 We then apply rKFP to 13C-labeled glucose time series data collected from cell

267 Our results show that as few as two 13C labeled residues can be detected in a 40 residue pro

268 Furthermore, the observation of two 13C peaks in solid-state NMR indicates very stable dicho

269 ng the conversion of hyperpolarized [U-2H, U-13C]glucose to lactate using 13C magnetic resonance spec

270 ributions at each position for the uncoupled 13C=O modes.

271 tic coupling among ring carbons in uniformly 13C-labeled samples.

272 g frame spin relaxation (R1rho) in uniformly 13C/15N labeled RNA samples.

273 -to-nanosecond internal motions in uniformly 13C/15N-labeled RNAs that combines measurements of R1, R

274 NMR spectra were collected on uniformly 13C and 15N isotopically enriched, polyethylene glycol p

275 chemes using the fully protonated, uniformly 13C,15N-labeled protein GB1 at 40 kHz MAS rate with 1.6-

276 mall-cell lung cancer (NSCLC) with uniformly 13C-labeled glucose before tissue resection and determin

277 ine global secondary structure in uniformly (13C,15N)-enriched systems by simultaneously measuring di

278 2)Os, (190)Os, and (188)Os) and three unique 13C isotopomers (13C in ethylene, axial, and equatorial

279 Plasma and urinary [13C]R-equol and [13C]S-equol concentrations were measure

280 This study used 13C magnetic resonance spectroscopy to test whether chro

281 Here, we used 13C NMR spectroscopy to examine the metabolism of gliobl

282 Using 13C tracer labeling and two model systems, polystyrene/p

283 Using 13C,15N-labeled PSA, we applied a combination of heteron

284 arized [U-2H, U-13C]glucose to lactate using 13C magnetic resonance spectroscopy and spectroscopic im

285 amics at the level of a single residue using 13C=18O isotope-edited infrared spectroscopy.

286 a gastric emptying test by breath test using 13C octanoic acid coupled to a solid meal and answered a

287 ng mosquitoes was investigated in vivo using 13C solid-state NMR.

288 etics of S-(-)equol and R-(+)equol by using [13C] stable-isotope-labeled tracers to facilitate the op

289 Chemical shift dispersion due to the various 13C-NeuAc adducts on ST6Gal-I was observed in a 3D exper

290 epatic metabolism was analyzed using in vivo 13C/31P/1H and ex vivo 2H magnetic resonance spectroscop

291 The line shape analysis of VT 13C CPMAS and broad-band 2H NMR data were in remarkable

292 For this purpose, A. castellanii was 13C-labeled by incubation in buffer containing [U-(13)C(

293 of disulfide bonds, was then alkylated with 13C iodoacetic acid.

294 thynylbiphenyl at natural abundance and with 13C[triple bond]13CH and 15N[triple bond]C labeling is d

295 d methyl aldopyranosides singly labeled with 13C at different sites to confirm and extend prior corre

296 d melanotic melanoma cells were labeled with 13C precursors and changes in their metabolism was analy

297 and Ala residues are uniformly labeled with 13C, are nearly indistinguishable, indicating that the p

298 tyl groups in isolated native oligomers with 13C labeled acetyl groups and the extraction of orientat

299 es C uniformly with 15N but selectively with 13C' or 13Calpha.

300 Nuclear magnetic resonance experiments with [13C]formate, as well as 14C-labeling experiments, demons