ライフサイエンスコーパス: 20-hydroxyecdysone

1 soforms are induced as a primary response to 20-hydroxyecdysone.

2 chromosomes initiated by the molting hormone 20-hydroxyecdysone.

3 y to become pupally committed in response to 20-hydroxyecdysone.

4 ersion of cholesterol to the molting hormone 20-hydroxyecdysone.

5 one that includes the insect steroid hormone 20-hydroxyecdysone.

6 ing mutant larvae the insect steroid hormone 20-hydroxyecdysone.

7 NMR, IR, and mass spectra not only for pure 20-hydroxyecdysone (100-400 microg on column) but also t

8 gnificantly up-regulated after stimulated by 20-hydroxyecdysone (20-E) in vivo.

9 infections and find that the steroid hormone 20-hydroxyecdysone (20-HE) can regulate the quality of t

10 and influential roles of the steroid hormone 20-hydroxyecdysone (20-HE) during development, we tested

11 lly by the prepupal peak of the ecdysteroid, 20-hydroxyecdysone (20-HE).

12 culating titer of the insect molting hormone 20-hydroxyecdysone (20-HE).

13 e (Kc167) that differentiates in response to 20-hydroxyecdysone (20-HE).

14 -hydroxyecdysone-3-O-beta-D-glycopyranoside, 20-hydroxyecdysone, 20-hydroxyecdysone-3-O-beta-D-xylose

15 ogenesis is regulated by the steroid hormone 20 hydroxyecdysone (20E).

16 ated wing disk growth in vitro requires both 20-hydroxyecdysone (20E) and either brain extract or bom

17 embryos have very low titers of ecdysone and 20-hydroxyecdysone (20E) and fail to express IMP-E1 and

18 l-autonomous response to the steroid hormone 20-hydroxyecdysone (20E) and involves mitochondrial demi

19 we show that the Drosophila steroid hormone 20-hydroxyecdysone (20E) and its nuclear receptor direct

20 h induction of BR-C mRNA in the epidermis by 20-hydroxyecdysone (20E) and its suppression by JH were

21 o maximal levels within 12h by low levels of 20-hydroxyecdysone (20E) and repressed by physiologicall

22 culture, AaFTZ-F1 expression is inhibited by 20-hydroxyecdysone (20E) and superactivated by its withd

23 th and developmental hormones, the steroidal 20-hydroxyecdysone (20E) and the sesquiterpenoid juvenil

24 ector genes activated by the steroid hormone 20-hydroxyecdysone (20E) are dually controlled by the ec

25 tion occurs as levels of the steroid hormone 20-hydroxyecdysone (20E) are rising during the pupal sta

26 mis of the tobacco hornworm Manduca sexta by 20-hydroxyecdysone (20E) during larval and pupal molts,

27 Remarkably, 20-hydroxyecdysone (20E) has opposite effects on USP iso

28 Blood feeding triggers a 20-hydroxyecdysone (20E) hormonal cascade, which activat

29 a competence factor for the steroid hormone 20-hydroxyecdysone (20E) in Drosophila melanogaster meta

30 in day 2 fifth larval epidermis in vitro by 20-hydroxyecdysone (20E) in the absence of JH with dose-

31 r hormone receptor family that is induced by 20-hydroxyecdysone (20E) in the epidermis of the tobacco

32 te a key requirement for the steroid hormone 20-hydroxyecdysone (20E) in the maintenance of numerous

33 When day 2 fourth epidermis was exposed to 20-hydroxyecdysone (20E) in vitro, MHR4 mRNA appeared be

34 and the Manduca GV1 cell line is induced by 20-hydroxyecdysone (20E) in vitro.

35 The steroid hormone 20-hydroxyecdysone (20E) initiates metamorphosis in inse

36 ow that the male-transferred steroid hormone 20-hydroxyecdysone (20E) is a key regulator of monandry

37 ng insect metamorphosis, the steroid hormone 20-hydroxyecdysone (20E) is responsible for coordinating

38 The steroid 20-hydroxyecdysone (20E) is the primary regulatory hormo

39 r knowledge, because exposure to the steroid 20-hydroxyecdysone (20E) leads to a robust regulated sec

40 upon successive phases of rising and falling 20-hydroxyecdysone (20E) levels, leading to a cascade of

41 Tonic exposure to moderate levels of 20-hydroxyecdysone (20E) or its precursor, ecdysone, are

42 revealed that pulses of the steroid hormone 20-hydroxyecdysone (20E) regulate ganglionic fusion, but

43 stablished that fat-body remodeling requires 20-hydroxyecdysone (20E) signaling.

44 ca sexta in a pattern-specific manner as the 20-hydroxyecdysone (20E) titer rises for the larval molt

45 that includes the principal molting hormone, 20-hydroxyecdysone (20E), and ecdysone (E), which is the

46 The mechanism of 20-hydroxyecdysone (20E), but not of JH action, is well

47 are activated in larval organs cultured with 20-hydroxyecdysone (20E), consistent with EcR/USP acting

48 hat converts ecdysone (E) to the more active 20-hydroxyecdysone (20E), specifically in mature follicl

49 Here, we show that 20-hydroxyecdysone (20E), the active metabolite of ecdys

50 mmonly thought to be a hormone precursor and 20-hydroxyecdysone (20E), the physiologically active ste

51 n in direct response to the prepupal rise in 20-hydroxyecdysone (20E), whereas APR(4)s survive throug

52 pression of DHR3 and betaFTZ-F1 is part of a 20-hydroxyecdysone (20E)-triggered transcriptional casca

53 t development and metamorphosis regulated by 20-hydroxyecdysone (20E).

54 uggests its regulation by a steroid hormone, 20-hydroxyecdysone (20E).

55 metamorphosis through its active metabolite 20-hydroxyecdysone (20E).

56 rphosis is controlled by the steroid hormone 20-hydroxyecdysone (20E).

57 sis under the control of the steroid hormone 20-hydroxyecdysone (20E).

58 I), and the JH I induction is suppressed by 20-hydroxyecdysone (20E).

59 and cell autonomously by the steroid hormone 20-hydroxyecdysone (20E).

60 ikely candidate for sexual selection is male 20-hydroxyecdysone (20E).

61 to a blood-meal-initiated, elevated titer of 20-hydroxyecdysone (20E).

62 stasis and is essential for molting hormone (20-hydroxyecdysone; 20E) biosynthesis.

63 ed that the most prevalent phytoecdysteroid, 20-hydroxyecdysone (20HE), was secreted (leached) from i

64 ined and used to identify four ecdysteroids: 20-hydroxyecdysone-3-O-beta-D-glycopyranoside, 20-hydrox

65 -beta-D-glycopyranoside, 20-hydroxyecdysone, 20-hydroxyecdysone-3-O-beta-D-xylose and a hydroxyecdyst

66 After ingestion of blood, 20-hydroxyecdysone activates yolk protein precursor (YPP

67 We conclude that 20-hydroxyecdysone acts through the Broad-Complex to con

68 optimal concentration of the steroid hormone 20-hydroxyecdysone and with hemolymph taken from growing

69 exposure to the hormone and lower levels of 20-hydroxyecdysone, and by being sensitive to either 20-

70 We examine the role of juvenile hormone, 20-hydroxyecdysone, and insulin/insulin-like growth fact

71 been used for the analysis of a standard of 20-hydroxyecdysone- and ecdysteroid-containing plant ext

72 cid residues were identified as critical for 20-hydroxyecdysone binding.

73 ctly induced in larval epidermis in vitro by 20-hydroxyecdysone, but EcR-B1 mRNA accumulated more rap

74 The holoreceptor of 20-hydroxyecdysone consists of two nuclear receptors (NR

75 The steroid hormone 20-hydroxyecdysone coordinates the stages of Drosophila

76 iption in Drosophila Schneider S2 cells in a 20-hydroxyecdysone-dependent manner, via its interaction

77 The steroid hormone 20-hydroxyecdysone (ecdysone) activates a relatively sma

78 la development is regulated by two hormones, 20-hydroxyecdysone (ecdysone) and juvenile hormone.

79 Following an increase in the steroid 20-hydroxyecdysone (ecdysone) at the end of larval devel

80 In Drosophila, pulses of the steroid hormone 20-hydroxyecdysone (ecdysone) control the timing of the

81 metamorphosis, pulses of the steroid hormone 20-hydroxyecdysone (ecdysone) direct the destruction of

82 The steroid hormone 20-hydroxyecdysone (ecdysone) is the key regulator of po

83 which is coordinated by the steroid hormone 20-hydroxyecdysone (ecdysone) through the ecdysone recep

84 In Drosophila melanogaster, fluctuations in 20-hydroxyecdysone (ecdysone) titer coordinate gene expr

85 orphological response to the steroid hormone 20-hydroxyecdysone (ecdysone).

86 The insect steroid hormone 20-hydroxyecdysone enhanced BrdU incorporation into the

87 rge in the production of the steroid hormone 20-hydroxyecdysone from the prothoracic gland, the prima

88 us studies have suggested that production of 20-hydroxyecdysone in Drosophila and other arthropods in

89 an elevated response to the steroid hormone 20-hydroxyecdysone in mosquitoes in a state of arrest.

90 ons of premoult concentrations (10(-6) M) of 20-hydroxyecdysone in the epidermal and muscle tissue of

91 central nervous system, the steroid hormone 20-hydroxyecdysone induces a wide spectrum of cellular r

92 The steroid hormone 20-hydroxyecdysone is a key regulatory factor, controlli

93 The steroid insect molting hormone 20-hydroxyecdysone is believed to control critical aspec

94 he most abundant phytoecdysteroids including 20-hydroxyecdysone is yet to be clarified.

95 of exogenous and endogenous compounds, like 20-hydroxyecdysone (natural ligand of the ecdysone recep

96 Precocious application of 20-hydroxyecdysone on the first day of pupal life accele

97 increasing the levels of the steroid hormone 20-hydroxyecdysone or by decapitation.

98 xyecdysone, and by being sensitive to either 20-hydroxyecdysone or its precursor, ecdysone.

99 ding the mutants the steroid molting hormone 20-hydroxyecdysone, or the precursors of ecdysone biosyn

100 elements stimulating direct development (the 20-hydroxyecdysone pathway: Ecr, Shd, Broad; the Wnt pat

101 ocally identified in these extracts included 20-hydroxyecdysone, polypodine B, and integristerone A.

102 The steroid hormone 20-hydroxyecdysone (referred to here as ecdysone) direct

103 The Broad-Complex, a 20-hydroxyecdysone-regulated gene, is essential for the

104 Broad-Complex (BR-C) is a key member of the 20-hydroxyecdysone regulatory hierarchy that coordinates

105 uced in vitro by the insect molting hormone, 20-hydroxyecdysone, suggesting that this, or some relate

106 Bombyxin evidently acts together with 20-hydroxyecdysone to stimulate cell division and growth

107 Importantly, AaGATAr can override the 20-hydroxyecdysone transactivation of YPP genes, and its

108 cultured fat body became less abundant after 20-hydroxyecdysone treatment.

109 Later, high levels of 20-hydroxyecdysone trigger a wave of apoptosis within th

110 We have shown that the fly steroid hormone 20-hydroxyecdysone triggers both the elongation itself a

111 ered and orchestrated by the steroid hormone 20-hydroxyecdysone, which initiates a cascade of coordin

112 The insect steroid hormone 20-hydroxyecdysone works through a ligand-activated nucl