ライフサイエンスコーパス: 25-hydroxyvitamin D3

1 mice had greater than 50% reduction in serum 25-hydroxyvitamin D3.

2 date on the concentration of vitamin D3 and 25-hydroxyvitamin D3.

3 d that the secosteroid product of CYP2R1 was 25-hydroxyvitamin D3.

4 Klotho is a potent regulator of 1,25-hydroxyvitamin D3 [1,25(OH)2D3] formation and calcium

5 d hormone 1-34 [PTH(1-34)], forskolin, and 1,25-hydroxyvitamin D3 [1,25(OH)2D3].

6 The human 25-hydroxyvitamin D3-1alpha-hydroxylase (1alpha-OHase) g

7 f chronic hyperparathyroidism, expression of 25-hydroxyvitamin D3-1alpha-hydroxylase (CYP27B1) mRNA w

8 iol), is synthesized by the essential enzyme 25-hydroxyvitamin D3-1alpha-hydroxylase (CYP27B1), which

9 indicate that parathyroid hormone stimulates 25-hydroxyvitamin D3-1alpha-hydroxylase by acting on the

10 transcription of Cyp24a1 encoding the enzyme 25-hydroxyvitamin D3 24-hydroxylase involved in the cata

11 ne under the control of the highly inducible 25-hydroxyvitamin D3 24-hydroxylase promoter in a stably

12 he expression of the vitamin D3 target gene, 25-hydroxyvitamin D3 24-hydroxylase, can be repressed by

13 or to initiate the genomic transcription of 25-hydroxyvitamin D3 24-hydroxylase.

14 metabolites of vitamin D and analogs such as 25-hydroxyvitamin D3, 24,25-dihydroxyvitamin D3, and 1 a

15 several vitamin D-sensitive genes including 25-hydroxyvitamin D3-24 hydroxylase (Cyp24), osteopontin

16 e previously shown that RNA levels of kidney 25-hydroxyvitamin D3-24-hydroxylase (24(OH)ase), a key m

17 tations in the vitamin D catabolizing enzyme 25-hydroxyvitamin D3-24-hydroxylase (CYP24A1) were descr

18 tein and the vitamin D metabolizing protein, 25-hydroxyvitamin D3-24-hydroxylase, resulting in increa

19 ing the function of the mitochondrial enzyme 25-hydroxyvitamin D3-24-hydroxylase, which functions to

20 Intervention with a single dose of 25-hydroxyvitamin D3 (25(OH)D) is capable of suppressing

21 74), we used a case-cohort design to compare 25-hydroxyvitamin D3 (25(OH)D3 ) levels among infants wi

22 We assessed whether 25-hydroxyvitamin D3 (25(OH)D3) was associated with risk

23 different races and the association between 25-hydroxyvitamin D3 (25[OH]D) levels in pregnancy and t

24 e investigated the association between serum 25-hydroxyvitamin D3 (25[OH]D3) levels and food allergy

25 Three hundred fifty-nine pretreatment 25-hydroxyvitamin D3 (25[OH]D3) serum levels from the RI

26 Serum 25-hydroxyvitamin D3 [25(OH)D3] concentrations are curre

27 ization during childhood.We examined whether 25-hydroxyvitamin D3 [25(OH)D3] concentrations in stored

28 25-Hydroxyvitamin D3 [25(OH)D3] has recently been found

29 ulation of target genes.In placental tissue, 25-hydroxyvitamin D3 [25(OH)D3] was strongly correlated

30 We described the distribution of 25-hydroxyvitamin D3 [25(OH)D3], 3-epi-25(OH)D3, and 25(

31 utic utility of its less calcemic precursor, 25-hydroxyvitamin D3 [25(OH)D3], which is converted loca

32 duce CYP27b1 and subsequent bioconversion of 25-hydroxyvitamin D3 (25D3) into bioactive 1,25D3, leadi

33 ive precursor metabolite in the circulation, 25-hydroxyvitamin D3 (25OHD3), can influence IgE-mediate

34 We observed that, although 25-hydroxyvitamin D3 3beta-bromoacetate (25-OH-D3-3-BE),

35 all-trans retinol (A), 25-hydroxyvitamin D2, 25-hydroxyvitamin D3, alpha-tocopherol (E), gamma-tocoph

36 the skin of female mice and normalized serum 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 levels

37 tures of various bromoacetate derivatives of 25-hydroxyvitamin D3 and 1alpha,25-dihydroxyvitamin D3 a

38 a1 maintained a similar circulating level of 25-hydroxyvitamin D3 and 1alpha,25-dihydroxyvitamin D3.

39 d, vitamin D3 is metabolized in the liver to 25-hydroxyvitamin D3 and then in the kidney to its biolo

40 lacking a 1alpha-hydroxyl group (vitamin D3, 25-hydroxyvitamin D3, and 24R,25-dihydroxyvitamin D3) de

41 oncentration analytes (25-hydroxyvitamin D2, 25-hydroxyvitamin D3, and phylloquinone) were 25, 17, an

42 ing 25(OH)D (sum of 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3), calibrated to standard reference

43 Vitamin D must be converted to 25-hydroxyvitamin D3 (circulating form) and finally to t

44 birds having more access to sunlight, while 25-hydroxyvitamin D3 concentration was higher (P<0.05) o

45 25-hydroxyvitamin D3 concentrations were significantly l

46 A comparison of the 7- and 20-mug 25-hydroxyvitamin D3/d groups with the 20-mug vitamin D3

47 or the 20-mug vitamin D3/d and 7- and 20-mug 25-hydroxyvitamin D3/d groups, respectively.

48 a placebo, 20 mug vitamin D3, or 7 or 20 mug 25-hydroxyvitamin D3 daily throughout 10 wk of winter.

49 tamin D3 metabolism at all stages and plasma 25-hydroxyvitamin D3 depletion in the acute and latent p

50 nd that only lifelong treatment raised serum 25-hydroxyvitamin D3 from 173 nmol/L in controls to 290

51 d make use of normal serum concentrations of 25-hydroxyvitamin D3 in a given population is needed.

52 fference between retention of vitamin D3 and 25-hydroxyvitamin D3 in eggs was shown.

53 investigated the retention of vitamin D3 and 25-hydroxyvitamin D3 in eggs, vitamin D3 in margarine, a

54 iologically inert and must be metabolized to 25-hydroxyvitamin D3 in the liver and then to 1alpha,25-

55 can synthesize calcitriol from its precursor 25-hydroxyvitamin D3 (inactive precursor) [25(OH)D] upon

56 Levels of 25-hydroxyvitamin D3 increased with vitamin D3 plus calc

57 adults to investigate whether the intake of 25-hydroxyvitamin D3 is 5 times more potent in raising s

58 25-Hydroxyvitamin D3 is less efficacious but reproduces

59 Recommendations for 25-hydroxyvitamin D3 levels for PN patients are presente

60 corticosteroids (OCSs) were recorded, serum 25-hydroxyvitamin D3 levels were measured at the beginni

61 D deficiency was defined as a serum level of 25-hydroxyvitamin D3 < 20 ng/mL (equivalent to < 50 nM)

62 Airway epithelium converts 25-hydroxyvitamin D3 (storage form) to 1,25-dihydroxyvit

63 is had significantly lower concentrations of 25-hydroxyvitamin D3 than patients with either mild seps

64 The relative potency of 25-hydroxyvitamin D3 to vitamin D3 needs to be better de

65 Each microgram of orally consumed 25-hydroxyvitamin D3 was about 5 times more effective in

66 Concentration of 25-hydroxyvitamin D3 was higher (P<0.05) in July and Sep