ライフサイエンスコーパス: 2H

1 2H-5,10,15,20-Tetrakis-(3,5-di-tert-butyl)-phenylporphyr

2 (2E,4E,6Z,8Z)-8-(3',4'-Dihydro-1'(2H)-naphthalen-1'-ylidene)-3,7-dimethyl-2,3,6-o ctatrien

3 h primary amines generates aminophthalazin-1(2H)-ones in good overall yields.

4 e-catalyzed amination of 4-bromophthalazin-1(2H)-ones 4 with primary amines generates aminophthalazin

5 tetrahydroxy-6-methyl-3,4-dihydroanthracen-1(2H)-one (up to 82% for AflM) has also been observed in p

6 3,5-trifluoro-4-(4-oxo-3,4-dihydropyridin -1(2H)-yl)phenyl)oxazolidin-2-one (MRX-I), distinguished by

7 henyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acet amide (PF-06282999, 8) upon oral administrat

8 1H-inden-1-one (3), 3,4-dihydro-naphthalen-1(2H)-one (4), and cycloalkanones (5-7) were studied for t

9 t regioselective bromination of phthalazin-1(2H)-ones 3 with benzyltrimethylammonium tribromide (BTMA

10 es 2 with hydrazine to generate phthalazin-1(2H)-ones 3.

11 onate ([Cp*Rh(MeCN)3](SbF6)2) reacts with 1-(2H)-phthalazinones to promote a C-H functionalization ev

12 9-def :6,5,10-d'e'f']diisoquinoline-1,3,8,10(2H,9H)-tetraone) (PNPDI); and poly(9,9-bis(2-butyloctyl)

13 [15N, 2H]His8-PNP had reduced catalytic site chemistry larger

14 catalytic site chemistry by generating [15N, 2H]His8-PNP.

15 Increasing the fraction of 1H,1H,2H,2H-perfluorodecanethiol (PFDT) in the mixed-PFDT/olea

16 ntification of [Ru(eta(6)-p-cymene)Cl2(1H,1H,2H,2H-perfluorodecyl-3-(pyridin-3-yl)propanoate)], a rut

17 2H-perfluorooctyl) trichlorosilane or (1H,1H,2H,2H-perfluorooctyl) dimethylchlorosilane to a specific

18 By controlling the contact angle of (1H,1H,2H,2H-perfluorooctyl) trichlorosilane or (1H,1H,2H,2H-pe

19 ips were functionalized with trichloro(1H,1H,2H,2H-perfluorooctyl)silane on one side, to render the s

20 the FET performance, suggesting that the 1T/2H interface controls carrier injection into the channel

21 satile route for a selective synthesis of 2-(2H-indazol-2-yl)phenols.

22 Biomimetic 2e(-) + 2H(+) is often viewed as a potential hydride donor.

23 characterized a key intermediate in 2e(-) + 2H(+) --> H2 catalysis.

24 er in a stepwise manner in the title 2e(-) + 2H(+) redox couple.

25 (+) dioxygen-reduction (to water) to a 2e(-)/2H(+) process (to hydrogen peroxide) only by increasing

26 This slurry allows the 2e(-)/2H(+) quinone/hydroquinone redox reactions while suppres

27 to 2-(1,3-dihydroxyallylidene)-1H-indene-1,3(2H)-dione or by loss of alcohol to indeno[1,2-b]pyran-4,

28 ), or 2-lithio-1,3-dithiane (14) to afford 3(2H)-furanones in modest to good yields (38-81%).

29 ve compound, 2-phenyl-1,2-benzisoselenazol-3(2H)-one (ebselen), displayed Ki values equal to 2.11 and

30 ion of 7-nitro-2-aryl-1,2-benzisoselenazol-3(2H)-ones 3 and 6 with sodium benzenetellurolate, NaTeC6H

31 mides to form 2-alkyl-1,2-benzisoselenazol-3(2H)-ones containing a C-Se-N bond.

32 library of 15 2-alkyl-1,2-benzisoselenazol-3(2H)-ones was prepared.

33 2-Alkyl-1,2-benzisoselenazol-3(2H)-ones, represented by ebselen (1a), are being studied

34 F-7-carboxamide) and 2,3-dihydrobenzofuran-3(2H)-one-7-carboxamide (DHBF-3-one-7-carboxamide) derivat

35 ene affords the corresponding dihydrofuran-3(2H)-ones in excellent yields via a formal 5-endo-trig cy

36 ng, amongst others, 4-hydroxy-2,5-dimethyl-3(2H)-furanone (furaneol), vanillin, (E)-4,5-epoxy-(E)-2-d

37 oil roasted almonds 4-hydroxy-2,5-dimethyl-3(2H)-furanone, 2,3-pentanedione, methional and 2-acetyl-1

38 the biosynthesis of 4-hydroxy-2,5-dimethyl-3(2H)-furanone, a major component in the characteristic fl

39 overall aroma were 4-hydroxy-2,5-dimethyl-3(2H)-furanone, methyl benzoate, (E)-2-hexenal, and hexana

40 linalool, limonene, 4-hydroxy-2,5-dimethyl-3(2H)-furanone, nonanal, and (Z)-3-hexenal.

41 key compound HDMF [4-hydroxy-2,5-dimethyl-3(2H)-furanone] contribute to the flavor of the fruit.

42 one (6-(4-fluorophenyl)-4-hydroxypyridazin-3(2H)-one) also retained modest activity as an inhibitor.

43 Several varied 6-phenyl-4-hydroxypyridazin-3(2H)-ones and 2-phenyl-5-hydroxypyrimidin-4(3H)-ones were

44 cysteine residue on the benzo[d]isothiazol-3(2H)-one core.

45 ave identified 2-phenyl benzo[d]isothiazol-3(2H)-ones as species-selective inhibitors of Plasmodium s

46 2-Phenyl benzo[d]isothiazol-3(2H)-ones display nanomolar inhibitory activity against P

47 log 2(or 5)-ethyl-4-hydroxy-5(or 2)-methyl-3(2H)-furanone.

48 p henyl)amino)-1H-pyrazolo[3,4-d]pyrimidin-3(2H)-one] using simultaneous and sequential dosing schedu

49 carbanion reagent studies suggest that the 3(2H)-furanone is formed in a cascade of reactions involvi

50 n, and subsequent ring closure to form the 3(2H)-furanone.

51 ylene] amino}spiro[isoindole-1,9'-xanthen]-3(2H)-one (DEMAX) for Al(III) chelation is described herei

52 gies, derivatives of 4, 4'-bis(5-nitro-1,2,3-2H-triazole) were designed, synthesized, and characteriz

53 perfluorophenyl; 3d, heptafluoropropyl; 3e, 2H-pyrroliumyl) were synthesized in two or three steps f

54 2-(naphthalen-1-ylmethyl)-1,2,4-triazine-3,5(2H,4H)-dione 11h was found to be selective over a number

55 f 2-substituted 6-hydroxy-1,2,4-triazine-3,5(2H,4H)-dione derivatives were synthesized as inhibitors

56 The 6-hydroxy-1,2,4-triazine-3,5(2H,4H)-dione pharmacophore appears metabolically resista

57 zin-1-yl)butyl)-4-methyl-1,2,4-tr iazine-3,5(2H,4H)dione) binding in monkey cerebellum.

58 8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic acid (1, Setipiprant/ACT-129968) were synt

59 -fluoro-3,4-dihyd ro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic acid, respectively, each composed of two e

60 The synthesis of 3,4-dihydro-1,2-oxazepin-5(2H)-ones and 2,3-dihydropyridin-4(1H)-ones from beta-sub

61 ate product similar to (CH(3)NH(3))(4)PbI(6).2H(2)O.

62 copper nanocluster, [Cu20H11{Se2P(OiPr)2}9] (2H), which exhibits an intrinsically chiral inorganic co

63 d by DFT calculations on [Cu20H11(Se2PH2)9] (2H') as a simplified model.

64 ile DABCO promotes 6pi cyclization to afford 2H-pyrans.

65 aldehydes and 2-bromoallyl sulfones afforded 2H- and 4H-chromenol derivatives endowed with a 3-arylsu

66 of substituted, functionalized alpha-alkoxy 2H-naphthalenones from readily available N-tosylhydrazon

67 c route provides practical access to 2-alkyl-2H-indazol-3-yl benzoates and 2-alkyl-1,2-dihydro-3H-ind

68 ,6]naphthyridin-6-ones starting from 3-amino-2H-chromen-2-one, again in high yields.

69 y in isotopically labeled PNP (13C, 15N, and 2H).

70 The 1H(+)/1e(-) and 2H(+)/2e(-) proton-coupled electron transfer (PCET) proc

71 rogen bond between the carboxylate group and 2H of the quinolinium ring, in addition to a 1,5-interac

72 is an anti-type of rinneite (K3NaFeCl6) and 2H perovskite related oxides such as Sr3Co2O6.

73 yl-lithium are a mixture of 1T (primary) and 2H (secondary) phases and oxidize rapidly with a typical

74 nitrogen leading to the synthesis of 2-aryl-2H-benzotriazoles has been accomplished with the help of

75 ithioates and alkyl 3,4-dihydro-2-oxo-4-aryl-2H-chromen-3-ylcarbamodithioates from 2-(alkylthio)thioa

76 rgent, one-step benchtop syntheses of N-aryl-2H-indazoles and furans by C-H bond additions to aldehyd

77 The syntheses of both N-aryl-2H-indazoles and furans have been performed on 20 mmol s

78 f diastereomeric 2-silyl-5,6-dihydro-6-aryl-(2H)-pyrans via [1,2]- and [1,4]-Wittig rearrangements to

79 homojunctions have abrupt interfaces between 2H and 1T' MoTe2 domains, possessing a potential differe

80 Edge sites of both 2H- and 1T'-MoS2 are proved to have comparable activitie

81 atalytic site chemistry was slowed for both [2H]PNP and [13C, 15N]PNP in proportion to their altered

82 Upon comparing the parameters for bulk 2H-MX2 (our work) with mono- and multi-layer MX2 (publis

83 mportant electronic band parameters for bulk 2H-MX2, including the band gap, direct band gap size at

84 nvestigate the electronic structures of bulk 2H-MX2.

85 hexagonal dislocation spirals form the bulk 2H layer stacking commonly observed, and plates containi

86 e bioisosteres, (b) elongated analogues, (c) 2H-chromene, and (d) 2-biphenyl derivatives.

87 ar copolymer chains containing phenyl-Si(CH3)2H pendants were the major product for both DMSS comonom

88 ridobiscarbonyl rhodium complexes [Rh(Ln)(CO)2H].

89 lling microscopy, the canonical CDW compound 2H-NbSe2 intercalated with Mn and Co, and show that the

90 formula Ca2[(HO3PC6H3COOH)2]2[(HO3PC6H3(COO)2H)(H2O)2].

91 Ca2[(HO3PC6H3COOH)2]2[(HO3PC6H3(COO)2H)(H2O)2].5H2O (Ca-PiPhtA-I) is obtained by slow crysta

92 tion patterns and produces the corresponding 2H-chromene products in good isolated yields.

93 A room-temperature-stable crystalline 2H-phosphirene (1) was prepared by treatment of an elect

94 itrile-functionalized porphyrin derivatives (2H-TPCN) with Co atoms in an ultrahigh vacuum environmen

95 for the preparation of allylic amide derived 2H-chromenes using an Overman rearrangement and a 6-endo

96 The allylic amide derived 2H-chromenes were converted to the corresponding coumari

97 droxymethyl-4-piperidyl]-3-ethyl-1,3-dihydro-2H benzimidazol-2-one] and the DOP receptor agonist SNC-

98 ymethyl)-4-piperidinyl]-3-ethyl -1,3-dihydro-2H-benzimidazol-2-one] to explore structure-activity rel

99 nthesis of highly functionalized 1,3-dihydro-2H-benzimidazol-2-ones via a ring opening of thiazolo[3,

100 scopy demonstrates that 1-methyl-1,3-dihydro-2H-benzimidazole-2-selone, H(sebenzim(Me)), a structural

101 = 1,3-bis[2,6-diisopropylphenyl]-1,3-dihydro-2H-imidazol-2-ylidene) provided only the alkene hydroary

102 ylphenyl)piperazine-1-yl]butyl}p-1,3-dihydro-2H-indol-2-one) and Cimbi-717 (3-{4-[4-(3-methoxyphenyl)

103 oxyphenyl)piperazine-1-yl]butyl}-1,3-dihydro-2H-indol-2-one) as selective 5-HT7R PET radioligands in

104 tory activity, and (4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N'-[(4-ethoxyphenyl)methylidene]benzo

105 3,4-dihydro-2H-1,2,4,3-triazaborol-3-yl-lithium 3 was synthesized an

106 d for 7-chloro-4-(2-fluoroethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide (BPAM121) at the h

107 4-cyclopropyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide (BPAM344) potentia

108 4-cyclopropyl-7-hydroxy-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide (BPAM521) potentia

109 cyclopropyl-7-(3-methoxyphenoxy)-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide, EC50 = 2.0 nM).

110 nthesis of 7-phenoxy-substituted 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides and their evaluat

111 of (S)-(-)-7,8-difluoro-3-methyl-3,4-dihydro-2H-benzo-[b][1,4]oxazine, which is a key precursor of th

112 sis of a wide family of 3-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazines bearing different pattern subst

113 a new class of 2-benzyl-3-phenyl-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazines has been discovered durin

114 chloro-substituted 4-cyclopropyl-3,4-dihydro-2H-benzothiadiazine 1,1-dioxides.

115 eceptor antagonist JNJ16259685 ((3,4-Dihydro-2H-pyrano[2,3-b]quinolin-7-yl)-(cis-4-methoxycyclohexyl)

116 ins to access highly substituted 3,4-dihydro-2H-pyrans.

117 demonstrated in the synthesis of 3,4-dihydro-2H-pyrido[1,2-a]pyrimidines.

118 ts in the pairwise generation of 3,4-dihydro-2H-pyrrole and an allylruthenium complex, which combine

119 The 3,4-dihydro-2H-pyrrole intermediates generated in situ are oxidized

120 O) and 2-ethoxycarbonyl-2-methyl-3,4-dihydro-2H-pyrrole-1-oxide (EMPO), were employed.

121 nthesized from easily accessible 3,4-dihydro-2H-pyrrole-2-carbonitriles in one-pot procedures.

122 thermore, oxidative couplings of 3,4-dihydro-2H-pyrrole-2-carbonitriles with copper(II)-salts furnish

123 s developed, employing 4-methoxy-1,5-dihydro-2H-pyrrol-2-one (13) as a single starting material to pr

124 cid (2) and 3-((5-butyl-3-methyl-5,6-dihydro-2H-pyran-2-yl)-methyl)-4-methoxy-4-oxobutyl benzoate (3)

125 rs in cis- and trans-substituted 3,6-dihydro-2H-pyrans allows the relative configuration at the C3 an

126 ration of 4,5-bis(organoselanyl)-3,6-dihydro-2H-pyrans and to 4-amino-butynol for the preparation of

127 udied using 5-bis(organoselanyl)-3,6-dihydro-2H-pyrans as substrate in a Kumada-type cross-coupling r

128 ive coupling reactions furnished 3,6-dihydro-2H-pyrans through a chemo- and regioselective 6-endo cyc

129 tion of 2,5-dihydro-1H-pyrroles, 3,6-dihydro-2H-pyrans, and pyrroles has been achieved through switch

130 th DBU, resulting in substituted 3,6-dihydro-2H-pyrans.

131 mistry in 3,6-oxygen-substituted 3,6-dihydro-2H-pyrans.

132 ng the relative configuration in 3,6-dihydro-2H-pyrans.

133 -2-ones 15-20, 8,9-disubstituted-3,9-dihydro-2H-purin-2,6-diamines 21-24 and 6-imino-1-phenyl-8,9-dis

134 9-14, 6-amino-8,9-disubstituted-3,9-dihydro-2H-purin-2-ones 15-20, 8,9-disubstituted-3,9-dihydro-2H-

135 2-substituted cyclic enamides and 3,4-dihyro-2H-pyrans.

136 nes, resulting from reaction of 2,3-diphenyl-2H-azirine and diazo compounds, do not produce indoles v

137 T (2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-2H-tetrazolium bromide) assay.

138 N-Methylation of 1,3-disubstituted 2H-pyrrolo[3,4-c]cinnolines occurs selectively at N5 und

139 rence of different reaction paths of double (2H(+)/2e(-)) free radical scavenging mechanisms was esti

140 Reaction energetics of the double (2H(+)/2e(-)), i.e., the first 1H(+)/1e(-) (catechol--> p

141 Limb girdle muscular dystrophy 2H is caused by mutations in the gene encoding the E3 ub

142 is generates a new FeMo-co state, denoted E4(2H)*, through the photoinduced re of the two bridging hy

143 ryoannealing at temperatures above 175 K, E4(2H)* reverts to E4(4H) through the oxidative addition (o

144 The oa recombination of E4(2H)* with the liberated H2 offers compelling evidence fo

145 oyloxy)-ethyl)-hexahydro-4-((E)-pent-2-enyl)-2H-chromene-6-carboxylate of polyketide origin, with act

146 A series of N(6)-substituted-5'-C-(2-ethyl-2H-tetrazol-5-yl)-adenosine and 2-chloro-adenosine deriv

147 Here, we study a prototypical example, 2H-NbSe2, by spin- and angle-resolved photoemission and

148 in downregulated PTEN protein levels (Figure 2H), downregulation of both mRNAs (Figure 2G), and incre

149 be replicated are those reported in Figures 2H, 3A, 3B, and S13.

150 opic ring-closing reaction to form the final 2H-chromene product.

151 H substitution for F on the alpha carbon for 2H polyfluorocarboxylic acids (2HPFCAs) and (ii) bearing

152 and a lowering of DeltaG(H) from +1.6 eV for 2H to +0.18 eV for 1T', comparable to 2H molybdenum disu

153 elds catalytic exchange rates (at the formal 2H(+)/H2 potential, at 0 degrees C) of 157 electrons (78

154 er than that of the much more commonly found 2H polytype.

155 mately 50 mV per decade can be achieved from 2H-phase catalysts where only the basal plane is exposed

156 ional analysis of the C-C bond cleavage from 2H(+) gives an intrinsic CKIE of 1.051 and suggests two

157 ntial transformation of the basal plane from 2H (trigonal prismatic) to 1T' (clustered Mo).

158 4-triazol-4-ium bromides, were prepared from 2H-azirines and triazolium phenacyl bromides using a sim

159 reaction proceeds through in situ generated 2H-indol-2-one (8).

160 The NWs form along the <11-20> 2H-MoTe2 crystallographic directions with lengths in the

161 (11)C]-(+)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol) to test the hypothesi

162 pp}2C5H3N (II) (hppH = 1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine) were protonated using [HNE

163 red the role of hppH [=1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine] to act not only as a base

164 omer yields the parent 4,5,6,7,8,9-hexahydro-2H-cyclooctatriazole, which could be characterized as a

165 d acids, the reaction provides the hexahydro-2H-thieno[3,2-c]pyran skeleton predominantly via oxonium

166 wis or Bronsted acids provides the hexahydro-2H-thiopyrano[4,3-b]furan preferentially through thioniu

167 tion to afford well-characterized hydrides ([2H](+) and [3H](+)) and mixed-valence derivatives ([2](+

168 he synthetically important lactol, 6-hydroxy-2H-pyran-3(6H)-one (3), proceeds cleanly in the presence

169 o be 2-amino-4-(2-hydroxy-3-(2-hydroxyethyl)-2H-benzo[b][1,4]oxazin-5-yl)-4-oxobutanoi c acid, which

170 t the Zeeman splitting, however, persists in 2H-MoTe2 bilayers, as a result of an additional degree o

171 The unique photomechanical response in 2H-MoS2 based nanocomposites is a result of the rich d e

172 a constant drive the moving vortex state in 2H-NbS2 superconductor exhibits a negative differential

173 in several structural polymorphs, including 2H, 1T and 1T'.

174 lective catalytic synthesis of 2H-indazoles, 2H-benzotriazoles, and related fused heterocyclic system

175 rgy demanding than the first ones indicating 2H(+)/2e(-) processes as inherent to catechol moiety.

176 1,6-Cyclization into 2H-1,4-oxazines with participation of the oxygen of este

177 hylsilyl)aryl triflates smoothly insert into 2H-azirines to form 2,3-diarylindoles with high selectiv

178 tion to ammonia is enabled by intramolecular 2H(+)/2e(-) proton-coupled electron transfer from the sa

179 Conjugated trienones and isomeric 2H-pyrans were found to engage in a novel cycloisomeriza

180 guided isolation of 3-(octahydro-9-isopropyl-2H-benzo[h]chromen-4-yl)-2-methylpropyl benzoate and met

181 ystallizing in anisotropic 1T' and isotropic 2H phases, respectively.

182 t exciton resonance A and B of the few layer 2H-MoS2 affecting optical absorption and subsequent mech

183 Here, using few layer 2H-MoS2 nanosheets, layer by layer process of nanocompos

184 Few-layer 2H MoTe2 is formed with high Te flux, while few-layer 1T

185 sile strains to the semiconducting few-layer 2H-MoS2 crystals in the nanocomposite resulted in spatia

186 [(LCu)2H](+) and the previously reported dimer (LCuH)2 can be

187 [(LCu)2H](+) is also an active precursor for catalytic CO2 hyd

188 [(LCu)2H](+) reacts stoichiometrically with CO2 to generate th

189 of the stoichiometric reaction between [(LCu)2H](+) and CO2 is dramatically increased in the presence

190 e to form a cationic dicopper hydride, [(LCu)2H]PF6.

191 The solid-state structure of [(LCu)2H](+) shows threefold symmetry about a linear Cu-H-Cu a

192 gnificantly enhanced CO2 reactivity of [(LCu)2H](+) under these catalytically relevant conditions, LC

193 The thermodynamic hydricity of [(LCu)2H](+) was determined to be 41.0 kcal/mol by measuring t

194 e addition of a large excess of DBU to [(LCu)2H](+) results in an equilibrium that forms LCu(DBU)(+)

195 used electron beam irradiation induced local 2H to 1T phase change in MoS2.

196 The most stable ATHP [M + 2H](2+) conformation at the "de-solvated" state correspo

197 ied for the AT-hook peptide 3 KRGRGRPRK [M + 2H](+2) during OSA-TIMS-FT-ICR MS.

198 al isomers (AT-hook peptide 3 KRGRGRPRK [M + 2H](+2)), and a complex mixture of polyaromatic hydrocar

199 a function of the trapping time for the [M + 2H](2+) and [M + 3H](3+) charge states.

200 tiple IMS bands were identified for the [M + 2H](2+) and for the [M + 3H](3+) charge states.

201 ionized preferentially as the dianion ([M - 2H](2-)) with a small contribution of the monoanion ([M

202 Product ion spectra generated from the [M - 2H](2-) precursor ions were dominated by the loss of HSO

203 a method of inducing the semiconductor-metal 2H-1T TMD phase transition.

204 the coumarin scopoletin (7-hydroxy-6-methoxy-2H-1-benzopyran-2-one) is the most abundant.

205 yloxy)-10-methylpentyl)-tetrahydro-13-methyl-2H-pyran-17-car boxylate (2) and (13-(methoxycarbonyl)-1

206 43654 [(2S)-1-(1H-indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan-2-a mine; ATP-com

207 S)-6-(2,9-dihydroxynonyl)-4-hydroxy-3-methyl-2H-pyran-2-one, 4-hydroxy-3-methyl-6-((2S,4R)-2,4,11-tri

208 R)-6-(2,9-dihydroxynonyl)-4-hydroxy-3-methyl-2H-pyran-2-one.

209 yl-(1H)-tetrazole-5-amine (1a) and 2-methyl-(2H)-tetrazole-5-amine (1b), although resulting in a comm

210 S6180 (4-[[3-(trifluoromethyl)phenyl]methyl]-2H-1,4-benzothiazin-3(4H)-one) inhibition at the atomist

211 optimization of the basal plane of monolayer 2H-MoS2 for HER by introducing sulphur (S) vacancies and

212 ineered low-resistance contacts on monolayer 2H-phase MoS2 basal plane lead to higher efficiency of c

213 A novel phase transition, from multilayered 2H-MoTe2 to a parallel bundle of sub-nanometer-diameter

214 Our efforts have led to compound 1, N-((2H-tetrazol-5-yl)methyl)-4-((R)-1-((5r,8R)-8-(tert-butyl

215 We propose that SLC4A11 is an NH3/2H(+) co-transporter exhibiting unique characteristics.

216 thoxy-4-2-[(4-methylpentyl)oxy]-3,4-dihydr o-2H-6-pyranylbutanoic acid (2) and 3-((5-butyl-3-methyl-5

217 dehydes provides the corresponding octahydro-2H-cyclopenta[c]furo[2,3-d]pyran derivatives in good yie

218 Ruthenium-catalyzed oxidative annulation of 2H-chromene-3-carboxamides with alkynes has been achieve

219 ladium-catalyzed direct (hetero)arylation of 2H-pyrazolo[3,4-b]pyridines has been developed.

220 icient Pd-catalyzed C-H functionalization of 2H-indazole at C3-position via an isocyanide insertion s

221 lds when R = alkyl or aryl, but oxidation of 2H-pyrans also gives alkyl cleavage products.

222 (S)-vacancies created on the basal plane of 2H-molybdenum disulfide (MoS2) using argon plasma exposu

223 ting patterns in multinuclear NMR spectra of 2H indicate that the chiral Cu20H11 core retains its C3

224 of these intermediates for the synthesis of 2H-1,4-oxazine N-oxides has been developed for a variety

225 scope of the new method for the synthesis of 2H-1,4-oxazine N-oxides is discussed, in addition to ini

226 ides a chemoselective catalytic synthesis of 2H-indazoles, 2H-benzotriazoles, and related fused heter

227 an efficient hole injection layer on top of 2H-MoTe2 due to favorable band-alignment.

228 Al composites reinforced with either IF- or 2H-WS2 particles, so as to elucidate their mechanism of

229 , enabling the formation of either 1T-WS2 or 2H-WS2 nanostructures.

230 dro-16-hydroxy-15-(methyl pentanoate)-14-oxo-2H-pyran-13-yl)-9-methyl-but-11-enyl benzoate (1), isobu

231 Here we demonstrate that novel 2-oxo-2H-chromene-3-carboxamidine derivative 5b, designed with

232 stituted phenylacetones to substituted 2-oxo-2H-pyran-3-carbonitriles at room temperature under alkal

233 conut and dried figs as 5,6-dihydro-6-pentyl-2H-pyran-2-one (C10 massoia lactone).

234 Photolysis of 3-methyl-2-phenyl-2H-azirine (1a) in argon-saturated acetonitrile does not

235 In contrast, photolysis of 2-methyl-3-phenyl-2H-azirine (1b) in acetonitrile yields heterocycles 6 an

236 scover modified salicylanilides and 3-phenyl-2H-benzo[e][1,3]oxazine-2,4(3H)-dione derivatives as pot

237 oic acid, HAvo; and 4-(2,2-difluoro-6-phenyl-2H-1lambda(3),3,2lambda(4)-dioxaborinin-4-yl)benzoic aci

238 06 (8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-2H-[1,2,4]triazolo[3,4-f][1,6]naphthyri din-3-one;dihydr

239 xo-cyclopentanecarboxylate 2 to phosphorated 2H-azirines 1.

240 With medium flux, few-layer in-plane 2H-1T' MoTe2 homojunctions are synthesized.

241 The fabrication of in-plane 2H-1T' MoTe2 homojunctions by the flux-controlled, phase

242 copy and Raman mapping confirm that in-plane 2H-1T' MoTe2 homojunctions have abrupt interfaces betwee

243 2) or [2,6-((i)Pr2PO)2-4-(MeO)C6H2]Fe(PMe2Ph)2H (3) have been tested for catalytic dehydrogenation of

244 the formula of [2,6-((i)Pr2PO)2C6H3]Fe(PMe2R)2H (R = Me, 1; R = Ph, 2) or [2,6-((i)Pr2PO)2-4-(MeO)C6H

245 The prepared 2H-chromenes demonstrated profound cytotoxic activity ag

246 ural transformation from trigonal prismatic (2H) to octahedral (1T) upon lithium or sodium intercalat

247 Ultrasonically exfoliated sheets are in pure 2H phase, and oxidize much more slowly.

248 electrons needed for the catalyzed reaction 2H(+) + 2e(-) right arrow over left arrow H2.

249 cle N(2) arylation in 1-beta-d-ribofuranosyl-2H-1,2,3-triazole substrate were designed in this study.

250 m dioxygenation of pyrene at an apical ring, 2H-naphtho[2,1,8-def]chromen-2-one (NCO), which was conf

251 lap near the Fermi level, but semiconducting 2H-MoTe2 is more stable and therefore more accessible sy

252 that are very different from semiconducting 2H-WS2 .

253 sforms them from the pristine semiconducting 2H phase to a distorted metallic phase.

254 ever, metals deposited on the semiconducting 2H phase usually form high-resistance (0.7 kOmega mum-10

255 s its transformation back to the more stable 2H polymorph through grain boundary pinning.

256 ermodynamically stable semiconducting state (2H) when mildly annealed in a nitrogen atmosphere.

257 ms exhibit a well-defined crystal structure (2H phase) and large grains reaching several hundred micr

258 hich forms a mixture of 5- and 7-substituted 2H-chromenes.

259 nedicarboxylate to access highly substituted 2H-furo[2,3-c]pyrrole bearing two rings and four stereoc

260 e and furnishes a wide range of 2-substiuted 2H-thiochromenes with excellent enantioselectivities (up

261 a higher-energy protonated phenyl tautomer (2H(+)) prior to C-C bond breaking would produce protonat

262 ructural data for [Cp(C5F4N)FeH(P(tBu)2N(tBu)2H)](+) provide a glimpse of how the H-H bond is oxidize

263 group A rotavirus VP3 contains a C-terminal 2H-phosphodiesterase domain that can cleave 2'-5' oligoa

264 7 (3-[(3-Chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrim idin-4-amine hydr

265 ymethyl)-3-pyridinyl]-4-{[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]amin o}-3-quinolinecarboxamide (72)

266 of cis- and trans-fused 3,4,4a,8a-tetrahydro-2H,5H-pyrano[2,3-b]pyran-7-carboxylates have been obtain

267 6-(4-Methoxybenzyl)-9-((tetrahydro-2H-pyran-4-yl)methyl)-8,9,10,11-tetrahydropyri do[4',3':

268 ctions produced diverse 1,3a,4,9b-tetrahydro-2H-furo[2,3-c]chromene-2,7-diols and 3,4,4a,9a-tetrahydr

269 ed 1,4-oxazines (morpholines) and tetrahydro-2H-1,4-thiazines (thiomorpholines), and seven-membered 1

270 azine (6) obtained from 4,4',5,5'-tetranitro-2H,2'H-3,3'-bipyrazole (4) by N-amination and N-azo coup

271 forded more than 30 2,3,5,6-tetrasubstituted 2H-pyrans.

272 The 2H basal plane is less active for the HER because it is

273 The 2H- and 4H-chromenol derivatives underwent regioselectiv

274 The 2H-pyran-2-one gibepyrone A and its oxidized derivatives

275 served increase in catalytic activity of the 2H basal plane.

276 Here we show that the activity of the 2H basal planes of monolayer MoS2 nanosheets can be made

277 carbenoid to endocyclic nitrogen atom of the 2H-azirine-2-carbaldimine.

278 High yields of the 2H-chromenes were achieved using a stepwise approach inv

279 r 1b points to the possibility that only the 2H-tetrazoles forms can give a direct access to nitrile

280 o a single tautomeric form, the 1H-3H or the 2H-3H, respectively.

281 sible electrocatalytic behavior close to the 2H(+)/H2 potential, making them paradigms for efficiency

282 However, the main reaction products were the 2H-chromenols.

283 Te6 interface and van der Waals gap with the 2H layers are preserved.

284 tion of thiazolo-, thiazino-, and thiazepino-2H-indazoles from o-nitrobenzaldehydes or o-nitrobenzyl

285 e target thiazolo-, thiazino-, or thiazepino-2H-indazole in good overall yield.

286 e derived from acyclic 2-oxo-butanoate 10 to 2H-azirine phosphine oxide 1 led to vinylogous N-acyl-al

287 ates derived from indenone-carboxylate 15 to 2H-azirines 1 led to the formation of functionalized N-s

288 eV for 2H to +0.18 eV for 1T', comparable to 2H molybdenum disulfide edges on Au(111), one of the mos

289 somerization, transformation of isoxazole to 2H-azirine, which is compatible with Ph3PAuNTf2, catalyz

290 entially alters the yields of 2,2,4-triamino-2H-oxal-5-one (Z) and 8-oxo-7,8-dihydro-2'-deoxyguanosin

291 -methyl-6-((2S,4R)-2,4,11-trihydroxyundecyl)-2H-pyran-2-one, and its unnatural 2R,4R-isomer starting

292 l recessive Charcot-Marie-Tooth disease type 2H on chromosome 8q13-21.1 was excluded by linkage analy

293 easuring the conversion of hyperpolarized [U-2H, U-13C]glucose to lactate using 13C magnetic resonanc

294 lized for the synthesis of 3,4-unsubstituted 2H-thiochromenes.

295 This can be done on various 2H-MoS2 nanostructures.

296 nalyzed using in vivo 13C/31P/1H and ex vivo 2H magnetic resonance spectroscopy before and during hyp

297 ent highly selective reaction of arynes with 2H-azirines allowing the synthesis of either N-unsubstit

298 d reactions of diazo carbonyl compounds with 2H-azirines, dramatically depend on the nature of substi

299 roxy-2,8-dimethyl-6-(3-methyl-2-bute n-1-yl)-2H-1-benzopyran-4,7(3H,8H)-dione; 3-[(2-O-beta-d-glucopy

300 occurring sibirinone, (E)-6-(pent-1-en-1-yl)-2H-pyran-2-one, and (E)-6-(hept-1-en-1-yl)-2H-pyran-2-on

301 )-2H-pyran-2-one, and (E)-6-(hept-1-en-1-yl)-2H-pyran-2-one.