ライフサイエンスコーパス: 4-hydroxybenzoate

1 ound to citrate, and weakly to gentisate and 4-hydroxybenzoate.

2 ol) at a rate about 1% of that with 3-chloro-4-hydroxybenzoate.

3 , involving the hydroxylation of benzoate to 4-hydroxybenzoate.

4 ull mutations completely blocked growth with 4-hydroxybenzoate.

5 obenzoate, ethyl 4-ethoxybenzoate, and ethyl 4-hydroxybenzoate.

6 biquinone biosynthetic pathway, 3-hexaprenyl-4-hydroxybenzoate.

7 -(4-hydroxyphenyl)-4-pentylfuran-3-yl)-ethyl-4-hydroxybenzoate (1), 2-2-[(4-hydroxybenzoyl)-oxy]-ethy

8 xylate 2-hydroxybenzoate, 3-hydroxybenzoate, 4-hydroxybenzoate, 2,3-dihydroxybenzoate, 2,4-dihydroxyb

9 l activator of pobA, the structural gene for 4-hydroxybenzoate 3-hydroxylase.

10 oA dehalogenase and thioesterase activities, 4-hydroxybenzoate 3-monooxygenase, and protocatechuate 3

11 ition by 3-chlorobenzoate, 2-chlorobenzoate, 4-hydroxybenzoate, 3-hydroxybenzoate, and benzoate.

12 catalyzes the hydrolysis of 4-HB-CoA to form 4-hydroxybenzoate (4-HB) and coenzyme A (CoA) in the fin

13 resses the ability of P. putida to transport 4-hydroxybenzoate (4-HBA) by preventing transcription of

14 Chemotaxis to the aromatic acid 4-hydroxybenzoate (4-HBA) by Pseudomonas putida is media

15 uctural genes required for the conversion of 4-hydroxybenzoate (4-HBA) to benzoyl-CoA by Rhodopseudom

16 ease from Pseudomonas putida that transports 4-hydroxybenzoate (4-HBA), were required for 4-HBA trans

17 s show that the Fe-O bond of the monodentate 4-hydroxybenzoate (4HB) inhibitor complex is significant

18 specificity switch from the native effector 4-hydroxybenzoate (4HB).

19 mediate involved in ubiquinone biosynthesis, 4-hydroxybenzoate, activates marRAB transcription in the

20 ase catalyzes the hydrolysis of 4-HBA-CoA to 4-hydroxybenzoate and CoA.

21 nal genes that convert the related compounds 4-hydroxybenzoate and cyclohexanecarboxylate to benzoyl-

22 from phenolic compounds including p-cresol, 4-hydroxybenzoate and numerous lignin monomers, to beta-

23 the accumulation of two aromatic substrates, 4-hydroxybenzoate and protocatechuate, against a concent

24 e, is known to metabolize this substrate via 4-hydroxybenzoate and protocatechuate, and evidence cons

25 ability to accumulate micromolar amounts of 4-hydroxybenzoate and protocatechuate.

26 2), 1,2-phenylenebis(methylene) bis(3-fluoro-4-hydroxybenzoate), and 1,4-phenylenebis(methylene) bis(

27 inetic analyses indicate 4-aminobenzoate and 4-hydroxybenzoate are preferred acyl substrates as PBS3

28 Ethyl 4-hydroxybenzoate at 1 mM, like benzocaine, elicited lit

29 dependent chemotaxis to vanillate, vanillin, 4-hydroxybenzoate, benzoate, protocatechuate, quinate, s

30 ant that was unable to grow anaerobically on 4-hydroxybenzoate but grew normally on benzoate.

31 coenzyme A during short-term uptake of [14C]4-hydroxybenzoate, but benzoyl coenzyme A was the major

32 because anaerobic growth of R. palustris on 4-hydroxybenzoate, but not on benzoate, was retarded unl

33 rerythraea strain 34H encodes a 3-octaprenyl-4-hydroxybenzoate carboxylase (CpsUbiX, UniProtKB code:

34 , 3-fluoro-4-hydroxybenzoate (FHB), 3-chloro-4-hydroxybenzoate (CHB), and 3-iodo-4-hydroxybenzoate (I

35 ing frames, divergently transcribed from the 4-hydroxybenzoate coenzyme A ligase gene, hbaA, were ide

36 h this organism converts 4-chlorobenzoate to 4-hydroxybenzoate consists of three enzymes: 4-chloroben

37 hate-, and metal-ion-independent, reversible 4-hydroxybenzoate decarboxylase (4-HOB-DC) from the obli

38 ate (MHB), 4-hydroxybenzoate (PHB), 3-fluoro-4-hydroxybenzoate (FHB), 3-chloro-4-hydroxybenzoate (CHB

39 s hardly detectable, and the mutant required 4-hydroxybenzoate for growth underlining the importance

40 3-chloro-4-hydroxybenzoate (CHB), and 3-iodo-4-hydroxybenzoate (IHB)] are reported at 2.0-2.2 A resol

41 way by which 4-chlorobenzoate is degraded to 4-hydroxybenzoate in the soil-dwelling microbe Pseudomon

42 We conclude that benzocaine and 4-hydroxybenzoate interact with the open and inactivated

43 The anaerobic degradation of 4-hydroxybenzoate is initiated by the formation of 4-hyd

44 l novobiocin analogue, in which the 3-prenyl-4-hydroxybenzoate of novobiocin is replaced with a tetra

45 droxybenzoate, 3,4,5-trihydroxybenzoate, 3-F-4-hydroxybenzoate, or vanillate.

46 ate 4-hydroxybenzoyl-CoA, hydrolysis to form 4-hydroxybenzoate, oxidation to yield protocatechuate, a

47 The 4-hydroxybenzoate permease PcaK was shown to modulate th

48 henylacetate (PHP), 3-hydroxybenzoate (MHB), 4-hydroxybenzoate (PHB), 3-fluoro-4-hydroxybenzoate (FHB

49 ible for decarboxylation of the 3-octaprenyl-4-hydroxybenzoate precursor.

50 s used for the detection and quantitation of 4-hydroxybenzoate preservatives, methylparaben, ethylpar

51 es [1,3-phenylenebis(methylene) bis(3-fluoro-4-hydroxybenzoate) (RA-2), 1,2-phenylenebis(methylene) b

52 and iron-sulfur cluster-containing 3-chloro-4-hydroxybenzoate reductive dehalogenase from Desulfitob

53 benzoate, which are isomers of gentisate and 4-hydroxybenzoate respectively that are not metabolized

54 iquinone biosynthesis and that the supply of 4-hydroxybenzoate, the side-chain shortened version of p

55 lected by demanding the inability to convert 4-hydroxybenzoate to a toxic metabolite.

56 five enzymes required for the conversion of 4-hydroxybenzoate to tricarboxylic acid cycle intermedia

57 Benzoate inhibited 4-hydroxybenzoate uptake but was not a substrate for Pca

58 by two competitive pathways, one leading to 4-hydroxybenzoate via elimination of the enolpyruvyl sid

59 The Vmax for uptake of 4-hydroxybenzoate was at least 25 nmol/min/mg of protein

60 in E. coli with conversion of chorismate to 4-hydroxybenzoate, which is then prenylated and decarbox

61 actic response by facilitating the uptake of 4-hydroxybenzoate, which leads to the accumulation of be

62 and 1,4-phenylenebis(methylene) bis(3-fluoro-4-hydroxybenzoate)] with inhibitory efficacy as determin

63 ituted benzoates such as 4-aminobenzoate and 4-hydroxybenzoate, with moderate activity on benzoate an