ライフサイエンスコーパス: 40S ribosomal subunit

1 subunit and prevent its association with the 40S ribosomal subunit.

2 S rRNA and diminished cellular levels of the 40S ribosomal subunit.

3 es and is required for the biogenesis of the 40S ribosomal subunit.

4 ransfers the initiator methionyl tRNA to the 40S ribosomal subunit.

5 action explains how eIF1 is recruited to the 40S ribosomal subunit.

6 ps0 proteins are essential components of the 40S ribosomal subunit.

7 ubunit and prevents its association with the 40S ribosomal subunit.

8 e structure around and within the developing 40S ribosomal subunit.

9 ubunit and prevents its association with the 40S ribosomal subunit.

10 suggesting that Ski2w is associated with the 40S ribosomal subunit.

11 eIF4A and eIF3 and which associates with the 40S ribosomal subunit.

12 ding of both methionyl-tRNAi and mRNA to the 40S ribosomal subunit.

13 e binding of methionyl-tRNAi and mRNA to the 40S ribosomal subunit.

14 the large, multiprotein eIF3 complex to the 40S ribosomal subunit.

15 in the decoding center of the A site of the 40S ribosomal subunit.

16 n in RPS19, which encodes a component of the 40S ribosomal subunit.

17 es a binding interface that clashes with the 40S ribosomal subunit.

18 insert fully into the P decoding site on the 40S ribosomal subunit.

19 nary complex (TC), which is recruited to the 40S ribosomal subunit.

20 al ribosome entry site (IRES) to recruit the 40S ribosomal subunit.

21 domain IIId(1) is crucial for recruiting the 40S ribosomal subunit.

22 first step in the recruitment of mRNA to the 40S ribosomal subunit.

23 aryotic ribosomes located on the head of the 40S ribosomal subunit.

24 F4E binding to eIF4G nor eIF3 binding to the 40S ribosomal subunit.

25 control an early step in the assembly of the 40S ribosomal subunit.

26 S can form a binary complex with an eIF-free 40S ribosomal subunit.

27 n through its interactions with eIF3 and the 40S ribosomal subunit.

28 in RPS15, a gene encoding a component of the 40S ribosomal subunit.

29 he mRNA of other translation factors and the 40S ribosomal subunit.

30 ential step during cytoplasmic maturation of 40S ribosomal subunits.

31 s is dramatically reduced relative to mature 40S ribosomal subunits.

32 e 18S rRNA, a late step in the maturation of 40S ribosomal subunits.

33 to yield the 18S ribosomal RNA component of 40S ribosomal subunits.

34 y complex (TC), promoting its recruitment to 40S ribosomal subunits.

35 initiation complex and co-sediments with the 40S ribosomal subunits.

36 t for cell growth when there is a deficit of 40S ribosomal subunits.

37 g, resulting in a reduction in the number of 40S ribosomal subunits.

38 e 3' end of 18S rRNA and formation of active 40S ribosomal subunits.

39 eIF3k colocalizes with eIF3 on 40S ribosomal subunits.

40 18S rRNA, which led to reduced formation of 40S ribosomal subunits.

41 es G1575 of rRNA in the P-site of the small (40S) ribosomal subunit.

42 small factors, eIF1 and eIF1A, to the small (40S) ribosomal subunit.

43 pecifically binds to the mRNA 5' m7G cap and 40S ribosomal subunit, a complex of 18S rRNA and multipl

44 Levels of the 40S ribosomal subunit and 18S rRNA were not significantl

45 try site (IRES) that can autonomously bind a 40S ribosomal subunit and accurately position it at the

46 entry site (IRES) that directly binds to the 40S ribosomal subunit and enables translation initiation

47 RPS29 is a component of the small 40S ribosomal subunit and essential for rRNA processing

48 nonstructural protein 1 (nsp1) binds to the 40S ribosomal subunit and inhibits translation, and it a

49 nown GTPase required for biosynthesis of the 40S ribosomal subunit and interacts with Rcl1, an essent

50 mutation in helix h5 of the 18S rRNA in the 40S ribosomal subunit and intragenic mutations in domain

51 ow the HCV IRES RNA binds human eIF3 and the 40S ribosomal subunit and positions the start codon for

52 elix 23 of 18S rRNA during its assembly into 40S ribosomal subunits and (2). a stem-loop structure in

53 don in an assay for detecting the binding of 40S ribosomal subunits and 43S ribosomal complexes to th

54 ealing that AROS selectively associates with 40S ribosomal subunits and also with polysomes.

55 us internal ribosomal entry site (IRES) with 40S ribosomal subunits and eukaryotic translation initia

56 Assembly of 40S ribosomal subunits and repression of RPS14B were als

57 eIF3 binds to 40S ribosomal subunits and stimulates recruitment of Met

58 actor 2 (eIF2) binds Met-tRNA(i)(Met) to the 40S ribosomal subunit, and previous studies identified S

59 iator Met-tRNA, associated with eIF2-GTP and 40S ribosomal subunit, and the cognate start codon of th

60 mpaired growth, reduced levels of the small (40S) ribosomal subunit, and a block in processing 20S rR

61 nct pathways for Met-tRNA(i) delivery to the 40S ribosomal subunit are identified, but which one pred

62 60S and 40S ribosomal subunits are assembled in the nucleolus an

63 yeast and human PRMT3 cosedimented with free 40S ribosomal subunits, as determined by sucrose gradien

64 host proteins to organize RNA structure for 40S ribosomal subunit assembly.

65 t premature translation initiation on small (40S) ribosomal subunit assembly intermediates by blockin

66 he hepatitis C virus (HCV) IRES bound to the 40S ribosomal subunit at about 20 A resolution.

67 al binding of particular mRNAs to eukaryotic 40S ribosomal subunits before translation may also selec

68 Late in their maturation, nascent small (40S) ribosomal subunits bind 60S subunits to produce 80S

69 s in the eIF3c RNA-binding motif also reduce 40S ribosomal subunit binding to eIF3, and inhibit eIF5B

70 According to the canonical mechanism, 40S ribosomal subunit binds to the 5'-end of messenger R

71 ellular factors revealed specific binding to 40S ribosomal subunits but not to other cellular compone

72 When S6 is a component of the 40S ribosomal subunit complex, DAPK selectively phosphor

73 pactamycin, allowing functional analysis of 40S ribosomal subunits containing synthetic 18S rRNAs by

74 promote association of messenger RNA to the 40S ribosomal subunit during translation initiation.

75 pre-initiation complex (PIC) containing the 40S ribosomal subunit, eIF1, eIF1A, eIF3, ternary comple

76 irst, 43S preinitiation complexes comprising 40S ribosomal subunits, eIFs 3, 2, 1, and 1A, and tRNA(M

77 48S initiation complexes, consisting of the 40S ribosomal subunit, eukaryotic initiation factor (eIF

78 s, a 43S preinitiation complex (comprising a 40S ribosomal subunit, eukaryotic initiation factor 3 (e

79 tiation complex (43S PIC), consisting of the 40S ribosomal subunit, eukaryotic initiation factors (eI

80 onstants of the factors and the yeast small (40S) ribosomal subunit for the first time.

81 displacement of initiation factors from the 40S ribosomal subunit in 48S initiation complexes and jo

82 displacement of initiation factors from the 40S ribosomal subunit in initiation complexes and its jo

83 gically phosphorylates the S6 protein of the 40s ribosomal subunit in response to mitogenic stimuli a

84 The position of mRNA on 40S ribosomal subunits in eukaryotic initiation complexe

85 ike hRio2, are associated with precursors of 40S ribosomal subunits in human cells.

86 Binding of Met-tRNAi to the small (40S) ribosomal subunit, in a ternary complex (TC) with e

87 tion initiation, 43S complexes, comprising a 40S ribosomal subunit, initiator transfer RNA and initia

88 The delivery of Met-tRNA(i) to the 40S ribosomal subunit is thought to occur by way of a te

89 Purified 40S ribosomal subunits lacking Rps25 are unable to bind

90 The eukaryotic 40S ribosomal subunit locates the translation initiation

91 ast ribosomal protein rpS14 in late steps of 40S ribosomal subunit maturation and pre-rRNA processing

92 In eukaryotes, 40S ribosomal subunits move from their recruitment site

93 proteolysis reveals that eIF3 binding to the 40S ribosomal subunit occurs through many redundant inte

94 ranslational initiation codon for MOCO1-A by 40S ribosomal subunits occurs, allowing recognition of t

95 kilodalton complex that controls assembly of 40S ribosomal subunits on messenger RNAs (mRNAs) bearing

96 us, the TGEV nsp1 protein was unable to bind 40S ribosomal subunits or promote host mRNA degradation.

97 eIF3 binds to the 40S ribosomal subunit, promotes the binding of methionyl

98 The 3'UTR interacts with 40S ribosomal subunit proteins residing primarily in a l

99 uction in growth rate and reduced amounts of 40S ribosomal subunits relative to wild-type cells.

100 ccharomyces cerevisiae are components of the 40S ribosomal subunit required for maturation of the 3'

101 Recruitment of mRNA to the 40S ribosomal subunit requires the coordinated interacti

102 rmore, disruption of RACK1's position at the 40S ribosomal subunit results in the failure of the mRNA

103 Detailed modeling of eIF3 and eIF4F onto the 40S ribosomal subunit reveals that eIF3 uses eIF4F or th

104 ates eIF2/GTP/Met-tRNA(i)(Met) attachment to 40S ribosomal subunits, scanning, start codon selection

105 evisiae RPS0A/B genes encode proteins of the 40S ribosomal subunit that are required for the maturati

106 ins may also account for the stalling of the 40S ribosomal subunit that is thought to contribute to t

107 f a neighboring proline residue resulting in 40S ribosomal subunits that were blocked from polysome f

108 weaken eIF3 binding to the HCV IRES and the 40S ribosomal subunit, thereby suppressing eIF2-dependen

109 G3BP interacts with 40S ribosomal subunits through its RGG motif, which is a

110 anism whereby initiation factors recruit the 40S ribosomal subunit to a cap structure at the 5' end o

111 on factors required for the recruitment of a 40S ribosomal subunit to an mRNA and for interacting wit

112 ral factors involved in the recruitment of a 40S ribosomal subunit to an mRNA.

113 the initiator methionyl-tRNA and mRNA to the 40S ribosomal subunit to form the 40S initiation complex

114 xclusively in the cytoplasm and binds to the 40S ribosomal subunit to gain access to translating mRNA

115 that eIF4A modulates the conformation of the 40S ribosomal subunit to promote mRNA recruitment.

116 to the 5'-UTR, allowing eIF4F to recruit the 40S ribosomal subunit to the 5'-end.

117 is in eukaryotes requires recruitment of the 40S ribosomal subunit to the messenger RNA (mRNA).

118 ent translation initiation by recruiting the 40S ribosomal subunit to the mRNA cap structure or inter

119 translation initiation factors that recruit 40S ribosomal subunits to the 5' end of eukaryotic mRNA.

120 structural core in eIF3 binds to the small (40S) ribosomal subunit, to translation initiation factor

121 he AUG codon, the toeprinting assay revealed 40S ribosomal subunits trapped behind the base paired st

122 aryotic initiation factor (eIF) 4G (type 2), 40S ribosomal subunits (types 3 and 4), and eIF3 (type 3

123 ype mRNA causes constraining of the entry of 40S ribosomal subunits upstream of uORF1.

124 tory role, we determined its position on the 40S ribosomal subunit using directed hydroxyl radical cl

125 processivity of scanning, no dissociation of 40S ribosomal subunits was detected as the distance from

126 Binding of salt-washed 40S ribosomal subunits was reduced 6-fold when the pyrim

127 e binding of initiator methionyl-tRNA to the 40S ribosomal subunit were assessed through eIF2B activi

128 Here, we labeled human 40S ribosomal subunits with a fluorescent SNAP-tag at ri