ライフサイエンスコーパス: 5' end

1 wo nucleotides (12th and 16th bases from the 5' end).

2 ed positive-strand RNAs corresponding to the 5' end.

3 drives cap-independent translation from the 5' end.

4 on of the chemical status of the substrate's 5' end.

5 e 3' end, and longer RNA substrates from the 5' end.

6 ved in both catalysis and positioning of the 5' end.

7 tions at their 3' end as compared with their 5' end.

8 rand breaks (DSBs) that carry adducts at the 5' end.

9 four unpaired nucleotides are present at the 5' end.

10 n, whereas others contain only ppp- at their 5'-end.

11 to recruit the 40S ribosomal subunit to the 5'-end.

12 accumulate owing to incomplete processing of 5' ends.

13 hairpin to form a bridge between the 3' and 5' ends.

14 e monitored with little sequence loss at the 5' ends.

15 led with fluorescent dyes at the same (3' or 5') end.

16 a single initiation site 71 nt from the most 5' end, an open reading frame of 1971 nt encoding a 657-

17 reading of a preassembled helicase over free 5'-ends, an event that can be blocked by attaching a ste

18 nucleotides of the 3' end duplicated at the 5' end and a 3' end produced by self-cleavage of a delta

19 In brief, miRNAs usually have a well-defined 5' end and a more flexible 3' end with the possibility o

20 The particular features at the 5' end and around the polyadenylation site indicate that

21 at contain a conserved UGU sequence at their 5' end and lack specificity for cytosine.

22 at least two unpaired nucleotides at the RNA 5' end and prefers three or more such nucleotides.

23 by recruiting host argonaute 2 (AGO2) to the 5' end and preventing decay mediated by exonuclease Xrn1

24 ribosomal subunit binds messenger RNA at the 5' end and scans in the 5' to 3' direction to locate the

25 The optimal spacing between the 5' end and the scissile phosphate appears to be eight nu

26 ation are generally inferred from transcript 5' ends and are thought to be either locally dispersed o

27 ncluding identification of the primary miRNA 5' ends and evaluation of ICP4 response.

28 ,919 human lncRNA genes with high-confidence 5' ends and expression profiles across 1,829 samples fro

29 lysis pipeline enables the profiling of both 5' ends and polyadenylation sites at near-base resolutio

30 mately 10-13 nucleotides downstream of their 5' ends and uses this capped fragment to prime viral mRN

31 ic of the FADH2 cofactor containing O at the 5'-end and 2'-deoxyadenosine at the 3'-end was studied b

32 g P oligo (carrying a phosphate group at the 5' end) and T oligo (carrying a T-tail at the 3' end), f

33 only a single nucleotide (12th base from the 5' end), and miR-10c, which differs by only two nucleoti

34 ethyl (H3K36me3) shifted within genes toward 5' ends, and histone H3 lysine 4 dimethyl (H3K4me2) exte

35 enosine (A) bases, a fluorophore unit at the 5'-end, and a quencher at the 3'-end.

36 of 8-mer T bases, a fluorophore unit at the 5'-end, and a quencher unit at the 3'-end.

37 Their distinctive 5' ends are accommodated by a small, mobile arch in the

38 g RNA ligase-mediated rapid amplification of 5' ends assay.

39 ing tiRNAs bear oligoguanine motifs at their 5'-ends, assemble G-quadruplex-like structures and inter

40 ight be incomplete with the lack coverage of 5' ends assessed by CAGE peaks.

41 ckdown inhibited detection of free HIV-1 RNA 5' ends at all time points.

42 ly 20-60 nt in length, often having the same 5' ends but differing in 3' ends by 1-nt steps.

43 Many of these arrays have multiple Helitron 5' ends, but a single 3' end.

44 F is presumably translated following genomic 5'-end cap-dependent ribosomal scanning, but its functio

45 e an unexpected intimate link between proper 5' end capping and subsequent pre-mRNA processing.

46 Our data reveal a pre-mRNA 5' end capping quality control mechanism in mammalian ce

47 homologs are a crucial component of the mRNA 5'-end capping quality control mechanism.

48 which help to degrade mRNAs with incomplete 5'-end capping.

49 locus that differ in terms of editing state, 5' end cleavage position, and poly(U) tail addition.

50 oval of Spo11-oligonucleotide complexes from 5' ends (clipping) and their resection to generate invas

51 The Qbeta hairpin on the 5 end confers affinity for the Qbeta coat protein (CP).

52 We show that ligases generate adenylated 5' ends containing a ribose characteristic of RNase H2 i

53 m the 3' end created by the ribozyme and the 5' end created from an endolytic cleavage by yeast at a

54 y induced recombination by cotransfection of 5'-end-deleted and 3'-end-deleted and replication-defici

55 plasmid derived and have a strong bias for a 5'-end deoxycytidine.

56 rial transcripts to a monophosphate triggers 5' end-dependent degradation by RNase E.

57 sphate-to-monophosphate conversion to induce 5' end-dependent RNA degradation is a two-step process i

58 activates flhDC expression by inhibiting the 5' end-dependent RNase E cleavage pathway.

59 Besides its role as the master regulator of 5'-end-dependent mRNA decay, RppH is important for the a

60 These properties are also manifested during 5'-end-dependent mRNA degradation in E. coli.

61 5'-End-dependent RNA degradation impacts virulence, stre

62 By contrast, a parallel pathway for 5'-end-dependent RNA degradation in that species appears

63 x pattern is found for nad3-rps12 mRNA whose 5' ends differ between several accessions.

64 he active site and demonstrates that the RNA 5'-end displaces sigma region 3.2 from its position near

65 y for RNAs with diverse phosphate-containing 5'-ends, excluding the higher eukaryotic mRNA cap.

66 expression data showed low expression at the 5' end exons and exon grouping.

67 nes revealed that the proximal 1.4 kb of the 5'-end-flanking regions containing several consensus mot

68 cence polarization/anisotropy (FP/FA) with a 5' end fluorescein-labeled pre-tRNAAsp substrate.

69 gh disrupting the weaker G-quadruplex at the 5'-end, followed by the stronger G-quadruplex at the 3'-

70 hairpin to deliver ribosomal subunits to the 5' end for translation initiation.

71 bers of the Potyviridae family rely on their 5' end for translation.

72 is likely determined by the stability of the 5'-end hairpin that the ribosome first encounters during

73 Finally, the 5'-end hairpin unravels, producing an extended state (Er

74 mocellum polynucleotide kinase (CthPnk), the 5' end-healing module of a bacterial RNA repair system,

75 mocellum polynucleotide kinase (CthPnk), the 5'-end-healing module of a bacterial RNA repair system,

76 all effect, whereas most mismatches near the 5' end impede strand exchange dramatically.

77 he difference in detection of free HIV-1 RNA 5' ends in infected DBR1 knockdown versus control cells

78 nome to a greater extent than those from the 5' end, indicating that it inhibits transcription initia

79 riven translation, it is unimpaired when the 5' end is blocked by a strong hairpin in a monocistronic

80 obe (CP) with methylene blue (MB) labeled at 5' end is modified on the pretreated electrode.

81 f both enzymes for decay intermediates whose 5' end is monophosphorylated.

82 rovides a long-distance interaction with the 5' end is unique.

83 ore, targets with mismatch location near the 5' end led to higher fluorescence intensity than those n

84 raded from both the 3' end but also from the 5' end, likely after decapping.

85 Transcripts with processed 5'-ends mapping approximately 70 nucleotides upstream of

86 an essential endonuclease that catalyzes the 5' end maturation of precursor tRNA (pre-tRNA).

87 One mechanism for mRNA 5' end maturation posits that sequence-specific pentatri

88 bonuclease P (mt:RNase P) is responsible for 5'-end maturation and is comprised of three proteins; mi

89 data reveal that mammalian RNAs can harbor a 5' end modification distinct from the classical m(7)G ca

90 iation with the unnatural analogue, yielding 5'-end modified transcripts that can be mono-phosphoryla

91 p mtDNA D-loop tandem repeat proximal to the 5' end, more than 95% of samples from the Mississippi Ri

92 ugh RTD normally degrades tRNAs with exposed 5' ends, mutations that sensitize SUP4oc to RTD were fou

93 es translation initiation independent of the 5' end N(7)-methylguanosine cap.

94 Eukaryotic mRNAs generally possess a 5' end N7 methyl guanosine (m(7)G) cap that promotes the

95 However, mammalian mRNAs can also carry a 5' end nicotinamide adenine dinucleotide (NAD(+)) cap th

96 od for expressing multiple gRNAs bearing any 5' end nucleotide, which gives dimeric RFNs a broad targ

97 p-0) and a 2'-O-methyl (2'-OMe) group to the 5'-end nucleotide ribose (Cap-1).

98 mimic 5-(E)-vinylphosphonate stabilizes the 5 end of the guide strand by protecting it from phosphat

99 ts Ago2 to tandem sites (S1 and S2) near the 5 end of the HCV genome, stabilizing it and promoting it

100 export factors that sequentially bind at the 5' end of a nuclear mRNA but are also reported to associ

101 ViReMa initially attempts to align the 5' end of a read to the reference genome(s) with the Bow

102 length of the nucleosome-free region at the 5' end of a subset of genes was changed in Fun30-deplete

103 pression in inflammatory states, maps to the 5' end of an intergenic region on Chr11p13 that is impli

104 An atypical +1 shift site, UUC C at the 5' end of CAG repeats, which has some resemblance to the

105 sively gained and lost, respectively, at the 5' end of coding genes during vertebrate evolution.

106 , 10, 30, and 50 consecutive adenines at the 5' end of DNA sequence, Poly A10/A30/A50), producing the

107 strated by a set of enhancers located at the 5' end of each cluster.

108 SL, derived from SL RNA, is spliced onto the 5' end of each mRNA.

109 nds are GC-rich regions often located in the 5' end of genes and normally protected from cytosine met

110 array of well-positioned nucleosomes at the 5' end of genes, but the extent and precise implications

111 periments revealed that H3K36ac peaks at the 5' end of genes, mainly on the two nucleosomes immediate

112 ulation of RNA polymerase II (Pol II) at the 5' end of genes.

113 GS and de novo heterozygous mutations in the 5' end of GMNN, encoding the DNA replication inhibitor g

114 ion of a lariat-like structure involving the 5' end of HIV-1 RNA during an early step in infection an

115 a premature termination codon present at the 5' end of intron 2 leads to nonsense-mediated decay of t

116 liver-specific microRNA-122 (miR-122) to the 5' end of its genome.

117 res at least two unpaired nucleotides at the 5' end of its substrates and prefers three or more but h

118 of copies of a 150 kb region containing the 5' end of KANSL1, a gene that is important for epigeneti

119 referentially induce deaminations toward the 5' end of minus-strand viral DNA, presumably because of

120 The initial 5' end of most protein-coding transcripts is removed by

121 ulting preinitiation complex (PIC) joins the 5' end of mRNA preactivated by eIF4F and poly(A)-binding

122 ost prevalent modified bases is found at the 5' end of mRNA, at the first encoded nucleotide adjacent

123 Initiation complexes formed even at the very 5' end of mRNA, implying that Met-tRNAi (Met) inspects m

124 erentially induce ribosome stalling near the 5' end of mRNAs, but rather acts at specific stalling si

125 G recruits the 40S ribosomal particle to the 5' end of mRNAs, facilitates scanning to the AUG start c

126 nit (SSU) processome, can be observed at the 5' end of nascent pre-rRNA.

127 composite RNA-binding site and captures the 5' end of pre-ribosomal RNA.

128 sing enzymes that catalyze maturation of the 5' end of precursor tRNAs in Eukaryotes.

129 (rs12425376-rs10843047-rs42294) covering the 5' end of PTHLH was associated with postmenopausal osteo

130 s this dramatic stabilization by capping the 5' end of RAD-51-ssDNA filaments.

131 By introducing a triphosphate group at the 5' end of siRNA (ppp-siRNA), gene silencing can be combi

132 stically increased ribosome occupancy at the 5' end of specific mRNAs under nutrient-limited conditio

133 New spacers are added invariably to the 5' end of the array; therefore, the first spacer matches

134 king a D-loop or a hairpin structure, on the 5' end of the blocking primer inhibited Pol epsilon from

135 Rare synonymous codon substitutions at the 5' end of the C-terminal half-domain further increased s

136 s the methylation status at 12 CpGs near the 5' end of the CpG island in two lung tumour samples for

137 and the cleavage sites are measured from the 5' end of the DNA substrate's RNA-paired region.

138 leotide composition; moreover, flanks at the 5' end of the exons have significantly lower SSM density

139 tide, instead using the template base at the 5' end of the gap to direct nucleotide binding and incor

140 gnizes the destruction box sequence near the 5' end of the geminin protein.

141 inatorial alternative splicing events at the 5' end of the gene allow for the generation of eight mRN

142 his effect, we evaluated the topology of the 5' end of the HIV-1 RNA genome during early infection wi

143 the distal 3' splice site (furthest from the 5' end of the intron) and germline cells showing a disti

144 acent proximal 3' splice site (closer to the 5' end of the intron).

145 ster bond between a bulged adenosine and the 5' end of the intron.

146 e 7-methylguanylate (m(7)G) cap found on the 5' end of the majority of mRNAs.

147 n size by one or more bases at the 3' and/or 5' end of the miRNA.

148 IC, in an open conformation, attaches to the 5' end of the mRNA and scans to locate the start codon,

149 o studies, ALYREF binds to a region near the 5' end of the mRNA in a CBP80-dependent manner.

150 binding of cap-binding complex (CBC) to the 5' end of the nascent U1 snRNA, which ultimately influen

151 plateaus in read counts appeared toward the 5' end of the negative-sense viral genome.

152 ained the RNA primer that is attached to the 5' end of the plus strand in RC DNA, suggesting that min

153 gulatory RNA elements located at the extreme 5' end of the positive-strand RNA genome.

154 ar the 3' end when the dye was tagged at the 5' end of the probe.

155 Also, it was shown that truncation of the 5' end of the qapR transcript permitted PA5507 translati

156 methylation of the CpG island located at the 5' end of the repeat expansion in blood, frontal cortex,

157 gy creates a ringlike conformation, with the 5' end of the resistant structure passing through the ri

158 by a modified HIV-switching mechanism at the 5' end of the RNA template (SMART) method to obtain full

159 strongly suppressed Nun cross-linking to the 5' end of the RNA, suggesting that GreA and GreB can ent

160 We reveal that the G-dC base pair at the 5' end of the RNA-DNA hybrid interferes with RNAP transl

161 teraction with a hairpin loop located at the 5' end of the RNA.

162 curs at the nuclease tunnel entrance and the 5' end of the Rpa-DNA complex.

163 a GG or GA dinucleotide genomic match at the 5' end of the sgRNA.

164 acer-blocking hairpin (SBH) structure at the 5' end of the single guide RNA (sgRNA), which abrogates

165 sence of a fluorescent label tethered to the 5' end of the solution-phase target.

166 nt is faster if the toehold is placed at the 5' end of the substrate; and that the displacement slows

167 stry we show that CsrA binds directly to the 5' end of the transcript encoding AcrAB.

168 conserved hairpin-loop structure towards the 5' end of the transcript.

169 een the 5' splice site of a pre-mRNA and the 5' end of the U1 snRNA.

170 Terminal deletions at the 5' end of the viral genome involving an RNA secondary st

171 form a protective oligomeric complex at the 5' end of the viral genome.

172 ) protein, which is covalently linked to the 5' end of the viral genome.

173 structural protein Gag and elements near the 5' end of the viral RNA known as packaging signal.

174 encoded VPg protein covalently linked to the 5' end of the viral RNA.

175 Several plant viruses encode elements at the 5' end of their RNAs, which, unlike most cellular mRNAs,

176 Furthermore, R-loops are enriched at the 5' end of those genes with promoter-proximal RNA polymer

177 This site maps to the 5' end of transcripts that fail to accumulate in ppr103

178 that catalyzes the essential removal of the 5' end of tRNA precursors.

179 In fact, the same two SNPs located at the 5' end of TSHR showed the most significant association w

180 antisense morpholino that base-pairs to the 5' end of U1 snRNA blocks splicing in the coupled system

181 st cell exonuclease Xrn1 likely loads on the 5' end of viral genomic RNA and degrades processively th

182 uz12) and the A-repeat region located at the 5' end of Xist RNA.

183 high-throughput sequencing to determine the 5' ends of A/WSN/33 (H1N1) influenza mRNAs.

184 the evolution of shortened forms (ves2) from 5' ends of canonical ves1 genes.

185 OR 4 (RPF4) supports the generation of extra 5' ends of ccmB transcripts in Landsberg erecta (Ler) an

186 lease activity to remove mismatches near the 5' ends of DNA substrates.

187 e motifs at the transcription start site and 5' ends of first introns (false discovery rate < 0.001)

188 We also show that GC-rich motifs at the 5' ends of footprints are found in yeast, calling into q

189 hyperphosphorylation of CTD Ser2 residues at 5' ends of genes that is conserved in yeast.

190 t OGA maps to the transcriptional start site/5' ends of genes, showing considerable overlap with RNA

191 upancy and positioning of nucleosomes at the 5' ends of genes.

192 nd processing signal (3' box), generates the 5' ends of HVS pre-miRNA hairpins.

193 FIT1 for RNA oligonucleotides resembling the 5' ends of IAV gene segments.

194 In plant mitochondria, the 5' ends of many transcripts are generated post-transcrip

195 ing a high-resolution method for analysis of 5' ends of mRNA transcripts.

196 ease P (mt-RNase P) complex that cleaves the 5' ends of mt-tRNAs from polycistronic precursor transcr

197 Here we report that the 5' ends of Okazaki fragments have significantly increase

198 , and these sites were concentrated near the 5' ends of ORFs.

199 atin by the SWR-C complex, is found near the 5' ends of protein-coding genes, and has been implicated

200 High-throughput approaches for profiling the 5' ends of RNA degradation intermediates on a genome-wid

201 Mapping of 5' ends of rpoE mRNA identified five new transcriptional

202 cumulation of ribosomes with immature 3' and 5' ends of the 16S rRNA.

203 in the extended state, but pulling on the 3'5' ends of the complementary strand reduces the strand-e

204 Conserved sequences on the 3' and 5' ends of the crRNA are anchored by proteins at opposit

205 hs of guanine-repeats are added at the 3' or 5' ends of the cytosine-repeats.

206 izes the replication origins, placed at both 5' ends of the linear chromosome, and initiates replicat

207 r miRNAs with their 5' ends shifted from the 5' ends of the miRNAs by a few nucleotides.

208 f two TOP2 subunits covalently linked to the 5' ends of the nicked DNA.

209 of AsiSI sites that are predominantly at the 5' ends of transcriptionally active genes.

210 in and are encoded primarily opposite to the 5' ends of transcripts, but are also found opposite ncRN

211 all ribonucleic acids (sRNAs), primarily the 5' ends of transfer RNAs (tRNAs) termed tRNA fragments (

212 yme, ribonuclease P (RNase P), processes the 5' ends of tRNA precursors (ptRNA) in cells and organell

213 ficity is proposed to arise by unpairing the 5'-end of duplex to permit the scissile phosphate dieste

214 nhancement of nascent RNA signal towards the 5'-end of genes promoting the identification of transcri

215 , observing that ribosomes accumulate on the 5'-end of genes through dynamic cycles of mRNA cleavage,

216 ing site by facilitating fluctuations in the 5'-end of helix P1.

217 echanism, 40S ribosomal subunit binds to the 5'-end of messenger RNA (mRNA) and scans its 5'-untransl

218 bad AUG context, within few nucleotides from 5'-end of mRNA and CUG start codon--is the most affected

219 e a broad range of functional handles at the 5'-end of RNA.

220 s a primary nucleation binding step near the 5'-end of the aptamer followed by a directional folding

221 active site and drives the extrusion of the 5'-end of the DNA primer out of the enzyme complex.

222 e base pairing transfers this complex to the 5'-end of the mRNA, where translation initiates.

223 the silencing activity when placed near the 5'-end of the passenger strand.

224 Okazaki fragment--either collision with the 5'-end of the preceding fragment (collision model) or sy

225 und gp32 clusters bind preferentially at the 5'-end of the ssDNA lattice.

226 zle has been why the AU dincucleotide at the 5'-end of the U1 snRNA is highly conserved, despite the

227 cts with the duplex between pre-mRNA and the 5'-end of U1 snRNA.

228 cription factor Rex and binds to the extreme 5'-end of yflS mRNA.

229 y, tRNA fragments were strongly enriched for 5'-ends of 18-19 or 30-34 nts in length; such tRNA fragm

230 and binds both the highly conserved 3'- and 5'-ends of the vRNA segment.

231 Mapping of the 5'-ends of these extension products to the rpsO-pnp inte

232 Spliced Leader (SL) sequence is added to the 5'end of each mRNA by trans-splicing.

233 Small RNAs that map to the 5'end of psaC RNA in the wild type but not in the mac1 m

234 kb region spanning the 3'end of MLH1 and the 5'end of the neighboring LRRFIP2, and marked by an isole

235 cing (5P-seq) that specifically captured the 5-end of processed transcripts and mapped the genome-wid

236 method (HIV-SMART [i.e.,switchingmechanismat 5' end ofRNAtranscript]) for next-generation sequencing

237 h transcription or that they can overlap the 5' end or even the entire gene.

238 ent with initiation of decay from either the 5' end or from an internal cleavage site.

239 that impede ribosome attachment at the mRNA 5' end or subsequent scanning of the 5' UTR, but whether

240 e blocked by attaching a steric block to the 5'-end or coating DNA with single-stranded DNA binding p

241 s in unspliced and spliced isoforms, and its 5' end overlaps with the cis-acting distal regulatory re

242 We also found evidence that the 5 end pairs alternatively with two different regions of

243 rthermore, we show that DUSP11 modulates the 5' end phosphate group and/or steady-state level of seve

244 end of a synthetic DNA molecule, so that the 5' end phosphoric acid group and multiple phosphate oxyg

245 pool of miR-34 is rapidly activated through 5'-end phosphorylation in an ATM- and Clp1-dependent man

246 The 5' end points of the imprinted transcript extensions did

247 Functionalization of the 5'-end position by a chemical label, a polydA tail, a pr

248 xpected cases of clade-specific variation in 5' end precision, occasional antisense loci, and putativ

249 lize the RNA/DNA hybrid, particularly at the 5' end, preventing loss of register between transcript a

250 ly on mitochondrial transcripts that are not 5' end processed.

251 function in ribosome maturation and 16S rRNA 5' end processing is conserved, the RBF1 protein has ass

252 e detailed characterization of mitochondrial 5' end processing.

253 They can possess RNA 5'-end pyrophosphohydrolase (PPH), decapping, and 5'-3'

254 er-specific oligonucleotides (TRs) via their 5'-end regions and to a capture probe-magnetic micropart

255 creates the structure that Exo1 requires for 5' end resection and HR initiation.

256 Meiotic DSB processing entails 5' end resection and preferred strand exchange with the

257 ogous recombination, but its relationship to 5' end resection and/or 3' end extension is poorly under

258 e for plant homeodomain finger 11 (PHF11) in 5' end resection at DNA double-strand breaks (DSBs).

259 The regulation of 5' end resection at DSBs and telomeres prevents genome i

260 sting that PHF11 acts (in part) by promoting 5' end resection at RPA-bound sites of DNA damage.

261 ir proteins and suggests that PHF11 mediates 5' end resection by negotiating RPA-coated DNA repair in

262 a previously unknown DDR factor involved in 5' end resection, ATR signaling, and HR.

263 logous recombination (HR), which begins with 5' end resection, mediated by exonuclease complexes, one

264 f distal DNA ends, and in addition, inhibits 5' end resection.

265 f MRE11 and CtIP, and protects the DSBs from 5' end resection.

266 lease 1 (Exo1), a 5'-exonuclease crucial for 5'-end resection to mediate DNA processing at stalled fo

267 Thus, mammalian cells have two distinct 5' end-resection pathways that are regulated by DNA dama

268 ups at nucleotide positions 1 and 5 from the 5 end, resulting in four methyl groups symmetrically pos

269 ith a blunt-ended, base-paired region at the 5'-end (reviewed in refs 1, 2, 3).

270 r the first time that the T. brucei telomere 5' end sequence - an important feature of the telomere t

271 genomic loci as the major miRNAs with their 5' ends shifted from the 5' ends of the miRNAs by a few

272 To generate a free 5' end, stalled replication forks must therefore be clea

273 c RNA-cDNA fragments can also be detected at 5' end stem-loops, although at much lower frequency.

274 nucleolytic degradation (resection) of their 5'-ending strands, we investigated the contribution of r

275 om each other in a tRNA-binding area and the 5'-end subcellular targeting motif area.

276 rveyed directly without being constrained by 5'-end tethering.

277 The two subunits are stacked at their 5'-end tetrads, and multiple stacking rotamers may be pr

278 se structure with a bound complementary cRNA 5' end that exhibits a major rearrangement of the subdom

279 s, facilitated a global analysis of internal 5' ends that are generated or acted upon by these enzyme

280 A. marginale, which contains repeats at the 5' ends that are useful for genotyping strains.

281 o reveal the complementary DNA strand with a 5'-end that is degraded iteratively by RecJ.

282 osome-binding 3'CITE that can connect to the 5' end through an RNA-RNA interaction and an adjacent eu

283 bonucleases that degrade RNA either from the 5' end to the 3' end, such as XRN4, or in the opposite d

284 ing the Ctgf gene from 15 kb upstream of its 5'-end to 10 kb downstream of its 3'-end to determine SO

285 olding of the aptamer around its target from 5'-end to 3'-end.

286 All 5 end-to-side-like portal-caval patients had a threadlik

287 nt, 17 had a portacaval shunt [subdivided in 5 end-to-side-like portal-caval, 7 side-to-side-like por

288 Herein, we globally identify the 5' end transcriptome of B. burgdorferi grown in culture

289 identified a new activity for these enzymes, 5'-end triphosphonucleotide hydrolase (TPH) instead of P

290 We investigated the effects of 5'-end truncated CRISPR RNA-guided Cas9 nuclease (tru-RG

291 ntly, 1,293 lincRNAs were corrected at their 5' ends using the putative lincRNA TSS regions predicted

292 DNA labeled at 5'end using 6-mercapto-1-hexhane (HS-ssDNA) is immobiliz

293 he generation and functional impact of miRNA 5' end variation.

294 sage of alternative promoters and N-termini, 5'-end variations and mutually-exclusive exons.

295 nd remains covalently bound to its substrate 5'-end via a phosphotyrosine linkage.

296 al run-on sequencing that quantifies nascent 5' ends, we show that transfer of full enhancer activity

297 s programmed with mRNAs containing different 5'-ends, we show that an MNK inhibitor, CGP57380, affect

298 rtion of cellular RNAs being 'capped' at the 5' end with NAD+, reminiscent of eukaryotic cap.

299 e of the overlap of the UL51 coding sequence 5' end with the UL52 promoter sequences, but partial del

300 ining enzymatic capture of m(7)G-capped mRNA 5' ends with high-throughput sequencing.