ライフサイエンスコーパス: 5,10-methylenetetrahydrofolate

1 of sarcosine is coupled to the formation of 5,10-methylenetetrahydrofolate.

2 one-carbon group to tetrahydrofolate to form 5,10-methylenetetrahydrofolate.

3 ernary complex formation with [32P]FdUMP and 5,10-methylenetetrahydrofolate.

4 the synthesis of thymidylate, which requires 5,10-methylenetetrahydrofolate (5,10-CH(2)-THF).

5 e ALL relapse risk by potentially increasing 5,10-methylenetetrahydrofolate and dTMP, enhancing DNA s

6 n units for dTMP biosynthesis in the form of 5,10-methylenetetrahydrofolate, are direct targets of As

7 Escherichia coli catalyzes the reduction of 5,10-methylenetetrahydrofolate (CH(2)-H(4)folate) by NAD

8 catalyze the NAD(P)H-dependent reduction of 5,10-methylenetetrahydrofolate (CH(2)-H(4)folate) to 5-m

9 THFR) catalyzes the NADH-linked reduction of 5,10-methylenetetrahydrofolate (CH(2)-H(4)folate) to 5-m

10 Escherichia coli catalyzes the reduction of 5,10-methylenetetrahydrofolate (CH(2)-H(4)folate) to 5-m

11 reductase (MTHFR) catalyzes the reduction of 5,10-methylenetetrahydrofolate (CH(2)-H(4)folate) to 5-m

12 ere 5-90 times higher, while K(m) values for 5,10-methylenetetrahydrofolate (CH(2)H(4)folate) were 1.

13 ahydrofolate (H4folate) to yield glycine and 5,10-methylenetetrahydrofolate (CH2-H4folate).

14 haromyces cerevisiae possesses two cytosolic 5,10-methylenetetrahydrofolate (CH2-THF) dehydrogenases

15 s the enzyme that catalyzes the oxidation of 5,10-methylenetetrahydrofolate (CH2-THF) in adult mammal

16 5,10-Methylenetetrahydrofolate dehydrogenase (MTD) catal

17 e contains a monofunctional NAD(+)-dependent 5,10-methylenetetrahydrofolate dehydrogenase (yMTD).

18 arboxamide ribonucleotide formyltransferase, 5,10-methylenetetrahydrofolate dehydrogenase, and 10-for

19 ng association in premenopausal women of the 5,10-methylenetetrahydrofolate dehydrogenase-1958A gene

20 viduals who were carriers of the very common 5,10-methylenetetrahydrofolate dehydrogenase-1958A gene

21 ine hydroxymethyltransferase (SHMT) generate 5,10-methylenetetrahydrofolate for de novo dTMP biosynth

22 SHMT1 generates 5,10-methylenetetrahydrofolate for de novo thymidylate b

23 A method for the determination of 5,10-methylenetetrahydrofolate in liver is described.

24 n of (1) from (3) gives the concentration of 5,10-methylenetetrahydrofolate in liver.

25 The folate coenzyme 5,10-methylenetetrahydrofolate is an important folate me

26 or previous metabolic studies that indicated 5,10-methylenetetrahydrofolate is preferentially directe

27 ces colon cancer risk, perhaps by increasing 5,10-methylenetetrahydrofolate levels for DNA synthesis,

28 tal cancer probably because higher levels of 5,10-methylenetetrahydrofolate may prevent imbalances of

29 Reduction of 5,10-methylenetetrahydrofolate (methyleneTHF), a donor f

30 s metabolized to methionine by the action of 5,10 methylenetetrahydrofolate reductase (MTHFR).

31 494del6, IVS6 -68C>T, 1122A>G, and 1053C>T); 5,10-methylenetetrahydrofolate reductase (MTHFR 677C>T a

32 s of genes coding for folate pathway enzymes 5,10-methylenetetrahydrofolate reductase (MTHFR) 677C-->

33 Four fetal genetic variants of the 5,10-methylenetetrahydrofolate reductase (MTHFR) and dih

34 The authors analyzed the 5,10-methylenetetrahydrofolate reductase (MTHFR) C677T g

35 The enzyme 5,10-methylenetetrahydrofolate reductase (MTHFR) catalyz

36 The enzyme 5,10-methylenetetrahydrofolate reductase (MTHFR) catalyz

37 y investigated whether a polymorphism in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene (C

38 r a variant form (the C677T genotype) of the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene an

39 viously reported that 2 polymorphisms in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene at

40 A common polymorphism in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene ha

41 the association between polymorphisms in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene, i

42 The enzyme 5,10-methylenetetrahydrofolate reductase (MTHFR) is invo

43 or for methionine synthesis, is catalyzed by 5,10-methylenetetrahydrofolate reductase (MTHFR).

44 to thymine (T) polymorphism in the gene for 5,10-methylenetetrahydrofolate reductase (MTHFR).

45 r V gene (Factor V Leiden), a variant in the 5,10-methylenetetrahydrofolate reductase gene (MTHFR), a

46 se, cystathionine-gamma-lyase, paraxonase 1, 5,10-methylenetetrahydrofolate reductase, betaine:homocy

47 eductase (MTHFR) catalyzes the conversion of 5,10-methylenetetrahydrofolate, required for purine and

48 hydrofolate; (2) chemical reduction of liver 5,10-methylenetetrahydrofolate (stabilized at pH 10) to

49 The sarcosine dehydrogenase and 5,10-methylenetetrahydrofolate synthase sites are 35 A a

50 (MTD) catalyzes the reversible oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydr

51 NA replication by blocking the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofola

52 reductase (MTHFR) catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofola

53 HFR, EC 1.5.1.20) catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofola

54 reductase (MTHFR) catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofola

55 netetrahydrofolate reductase (MTHFR) directs 5,10-methylenetetrahydrofolate toward methionine synthes