ライフサイエンスコーパス: 5-aminolevulinic acid

1 clinically approved PSs porfimer sodium and 5-aminolevulinic acid.

2 entachlorbiphenyl, an inducer of CYP1A2, and 5-aminolevulinic acid.

3 und heme b when expressed in the presence of 5-aminolevulinic acid.

4 roides 2.4.1 which catalyze the formation of 5-aminolevulinic acid.

5 S-catalyzed condensation of two molecules of 5-aminolevulinic acid.

6 Cells were incubated with PpIX pro-drug 5-aminolevulinic acid (5-ALA) at 0, 1, 2, 3, and 4 mM fo

7 Fluorescence-guided surgery using 5-aminolevulinic acid (5-ALA) is now a widely-used modal

8 X (PpIX), which is endogenously derived from 5-aminolevulinic acid (5-ALA) or its derivatives, is a p

9 A novel 5-aminolevulinic acid (5-ALA) prodrug was custom-designe

10 microneedles for improved dermal delivery of 5-aminolevulinic acid (5-ALA), which naturally gets conv

11 pical, oral, or parenteral administration of 5-aminolevulinic acid, a precursor for heme biosynthesis

12 tor deferoxamine and the porphyrin precursor 5-aminolevulinic acid (ALA) (mimicking intracellular pro

13 5-aminolevulinic acid (ALA) and carnosine have important

14 In mice treated with 5-aminolevulinic acid (ALA) and polyhalogenated aromatic

15 HMB-synthase activities and elevated urinary 5-aminolevulinic acid (ALA) and porphobilinogen (PBG), t

16 ation of the neurotoxic porphyrin precursors 5-aminolevulinic acid (ALA) and porphobilinogen (PBG), w

17 The tetrapyrrole precursor 5-aminolevulinic acid (ALA) inhibited Lhcb expression in

18 The synthesis of 5-aminolevulinic acid (ALA) is a key regulatory step for

19 5-aminolevulinic acid (ALA) is a precursor in the biosyn

20 Photodynamic therapy (PDT) with 5-aminolevulinic acid (ALA) is based upon the intracellu

21 bacteria, the heme and chlorophyll precursor 5-aminolevulinic acid (ALA) is formed from glutamate in

22 Photodynamic therapy (PDT) with topical 5-aminolevulinic acid (ALA) is increasingly employed for

23 5-Aminolevulinic acid (ALA) is the first committed subst

24 5-Aminolevulinic acid (ALA) is the first committed unive

25 The synthesis of 5-aminolevulinic acid (ALA) is the rate-limiting step fo

26 5-Aminolevulinic acid (ALA) is the universal precursor o

27 ranscripts for the two committed enzymes for 5-aminolevulinic acid (ALA) synthesis despite the marked

28 asymmetric condensation of two molecules of 5-aminolevulinic acid (ALA) to form porphobilinogen.

29 r increased ability to convert the precursor 5-aminolevulinic acid (ALA) to PPIX appeared to reinforc

30 talyzes the condensation of two molecules of 5-aminolevulinic acid (ALA), an essential step in tetrap

31 The common precursor to all tetrapyrroles is 5-aminolevulinic acid (ALA), and in Rhodobacter sphaeroi

32 ytes can be potently stimulated by exogenous 5-aminolevulinic acid (ALA), resulting in accumulation o

33 Metabolomic analysis revealed that 5-aminolevulinic acid (ALA), the first heme precursor, i

34 mice in a 129S6/SvEvTac background were fed 5-aminolevulinic acid (ALA), which results in hepatic UR

35 asymmetric condensation of two molecules of 5-aminolevulinic acid (ALA).

36 n IX (PPIX), can be enhanced in the cells by 5-aminolevulinic acid (ALA).

37 s been shown to have higher specificity than 5-aminolevulinic acid and can possibly play a complement

38 Fluorescence cystoscopy with 5-aminolevulinic acid and hexaminolevulinate has been sh

39 is caused by restriction on the formation of 5-aminolevulinic acid and protochlorophyllide.

40 mutant has a reduced capacity to synthesize 5-aminolevulinic acid and reduced CHLM activity compared

41 quantitative measurement of porphobilinogen, 5-aminolevulinic acid, and total porphyrin levels.

42 HL27, and contributes to feedback-control of 5-aminolevulinic acid biosynthesis, the rate-limiting st

43 Little is known about the movement of 5-aminolevulinic acid (delta-aminolevulinic acid; ALA) b

44 oroplasts by feeding these chloroplasts with 5-aminolevulinic acid, determined the relative levels of

45 Our results indicate that 5-aminolevulinic acid feeding stimulates Mg-chelatase ac

46 strongly accumulates in mutant leaves after 5-aminolevulinic acid feeding.

47 application of the photosensitizer precursor 5-aminolevulinic acid has therapeutic implications for t

48 tial use of the combination of tellurite and 5-aminolevulinic acid in antimicrobial therapy.

49 enzoporphyrin derivative monoacid ring A and 5-aminolevulinic acid-induced protoporphyrin IX, were st

50 ll as show the direct in vitro conversion of 5-aminolevulinic acid into cobyrinic acid using a mixtur

51 Hexyl-5-aminolevulinic acid is an ester form of 5-aminolevulin

52 creased synthesis of glutamate semialdehyde, 5-aminolevulinic acid, magnesium-porphyrins, and chlorop

53 ht photodynamic therapy using topical methyl 5-aminolevulinic acid (MAL) for actinic keratoses (AKs)

54 With this model, we demonstrated that 5-aminolevulinic acid-mediated sonodynamic therapy (ALA-

55 ed by favoring low-activity oligomers, while 5-aminolevulinic acid, Mg(2+), or K(+) stabilized high-a

56 droxybenzoic acid (3,4-AHBA), and a cyclized 5-aminolevulinic acid moiety, 2-amino-3-hydroxycyclopent

57 alloenzyme catalyzes the condensation of two 5-aminolevulinic acid molecules to form the tetrapyrrole

58 kinin contents and de-represses synthesis of 5-aminolevulinic acid of tetrapyrrole metabolism in dark

59 ment of tumor-specific fluorophores, such as 5-aminolevulinic acid, real-time microscopic visualizati

60 5-Aminolevulinic acid synthase (ALAS-1) is the first rat

61 and enzymatic assays indicate that erythroid 5-aminolevulinic acid synthase (Alas2) is decreased in h

62 actors that induce the expression of hepatic 5-aminolevulinic acid synthase 1 (ALAS1) result in the a

63 Marked overexpression of 5-aminolevulinic acid synthase 2 (Alas2) results from lo

64 These knock-out parasite lines, lacking 5-aminolevulinic acid synthase and/or ferrochelatase (FC

65 ms whereby increased cellular heme regulates 5-aminolevulinic acid synthase is by decreasing the stab

66 genase, and heme (200 nM); (c) Repression of 5-aminolevulinic acid synthase mRNA levels by zinc mesop

67 r a decrease in cellular heme might increase 5-aminolevulinic acid synthase mRNA stability and whethe

68 We found that: (a) The stability of 5-aminolevulinic acid synthase mRNA was markedly increas

69 eferoxamine; (b) This increased stability of 5-aminolevulinic acid synthase mRNA was reversed by the

70 romium mesoporphyrin significantly decreased 5-aminolevulinic acid synthase mRNA without increasing h

71 , heme-like, effect of zinc mesoporphyrin on 5-aminolevulinic acid synthase mRNA; (d) Among the sever

72 Hepatic 5-aminolevulinic acid synthase, the first and normally r

73 5-Aminolevulinic acid synthesis rates are increased and

74 In conjunction with the dark repression of 5-aminolevulinic acid synthesis, GUN4 phosphorylation mi

75 h codes for one of two isoenzymes catalyzing 5-aminolevulinic acid synthesis.

76 code isozymes that catalyze the formation of 5-aminolevulinic acid, the first step in the biosynthesi

77 chlorophyll share common intermediates from 5-aminolevulinic acid through protoporphyrin IX.

78 Furthermore, we show that the heme precursor 5-aminolevulinic acid, which is used as an antimicrobial

79 yl-5-aminolevulinic acid is an ester form of 5-aminolevulinic acid with improved uptake by tumor cell