ライフサイエンスコーパス: 60S ribosomal subunit

1 ulatory region located on the surface of the 60S ribosomal subunit.

2 nt ITS2 rRNA processing and synthesis of the 60S ribosomal subunit.

3 RNA makes up the major mass and shape of the 60S ribosomal subunit.

4 ghly conserved role in the maturation of the 60S ribosomal subunit.

5 for cell proliferation and biogenesis of the 60S ribosomal subunit.

6 A maturation or with decreased levels of the 60S ribosomal subunit.

7 the biogenesis and the nuclear export of the 60S ribosomal subunit.

8 13a was phosphorylated and released from the 60S ribosomal subunit.

9 g site connected to the GTPase center in the 60S ribosomal subunit.

10 and 5.8S rRNAs and in the biogenesis of the 60S ribosomal subunit.

11 se domain were primarily associated with the 60S ribosomal subunit.

12 ed structure that binds to 80S ribosomes and 60S ribosomal subunits.

13 tructure of the RQC complex bound to stalled 60S ribosomal subunits.

14 ether with Ltn1 and the AAA-ATPase Cdc48, to 60S ribosomal subunits.

15 ing and maturation steps for construction of 60S ribosomal subunits.

16 ernal T-shaped structure (TSS) that binds to 60S ribosomal subunits.

17 critical for late cytoplasmic maturation of 60S ribosomal subunits.

18 M directs the nuclear export of both 40S and 60S ribosomal subunits.

19 a late, cytosolic step of the biogenesis of 60S ribosomal subunits.

20 the Obg family involved in the biogenesis of 60S ribosomal subunits.

21 and Bop1 is necessary for the biogenesis of 60S ribosomal subunits.

22 e it physically interacts with Rat1p and pre-60S ribosomal subunits.

23 at eIF6 is not required for the stability of 60S ribosomal subunits.

24 ormation and deficiency of newly synthesized 60S ribosomal subunits.

25 cific factors required for the maturation of 60S ribosomal subunits.

26 se cells leads to a deficit in the cytosolic 60S ribosomal subunits.

27 it is an essential gene required for stable 60S ribosomal subunits.

28 volved in the biogenesis and/or stability of 60S ribosomal subunits.

29 NAs, leading to the formation of the 40S and 60S ribosomal subunits.

30 for a late step in biogenesis of the large (60S) ribosomal subunit.

31 NF90 as components of precursors to 60S (pre-60S) ribosomal subunits.

32 fivefold and reduces steady-state levels of 60S ribosomal subunits, 80S ribosomes, and polysomes.

33 mutant 25S ribosomal RNAS (rRNAs) in mature 60S ribosomal subunits, a process that requires ubiquiti

34 d Lsg1p, that are found associated with free 60S ribosomal subunits affinity purified with the nuclea

35 itiation complex, followed by joining of the 60S ribosomal subunit and formation of the 80S complex.

36 ric protein of about 26 kDa, can bind to the 60S ribosomal subunit and prevent its association with t

37 tion initiation factor 6 (eIF6) binds to the 60S ribosomal subunit and prevents its association with

38 tion initiation factor 6 (eIF6) binds to the 60S ribosomal subunit and prevents its association with

39 t a 2.5-A structure of the Trypanosoma cruzi 60S ribosomal subunit and propose a model for the stepwi

40 epletion of Dbp3p results in a deficiency of 60S ribosomal subunits and a delayed synthesis of the ma

41 that specifically and stably associates with 60S ribosomal subunits and nucleoli and is incorporated

42 a significant role in the binding of Ltn1 to 60S ribosomal subunits and that NTD mutations causing de

43 regions of FMR1 that mediate its binding to 60S ribosomal subunits and the interactions among the FM

44 size the 25S and 5.8S rRNA components of the 60S ribosomal subunit, and exonucleolytic 5' processing

45 les colocalized with poly(A+) mRNA, with the 60S ribosomal subunit, and with elongation factor 1alpha

46 We directly tracked the CrPV IRES, 40S and 60S ribosomal subunits, and tRNA using single-molecule f

47 ex process in which initiator tRNA, 40S, and 60S ribosomal subunits are assembled by eukaryotic initi

48 In eukaryotes, 40S and 60S ribosomal subunits are assembled in the nucleus and

49 In eukaryotes, 40S and 60S ribosomal subunits are assembled in the nucleus from

50 strate that structural domains of eukaryotic 60S ribosomal subunits are formed in a hierarchical fash

51 colocalization of NPM with maturing nuclear 60S ribosomal subunits, as well as newly exported and as

52 In Saccharomyces cerevisiae, the 60S ribosomal subunit assembles in the nucleolus and the

53 leles of rRNA-processing factors that affect 60S ribosomal subunit assembly accumulated Rpl11b-GFP in

54 ile the protein composition of various yeast 60S ribosomal subunit assembly intermediates has been st

55 iogenesis, we examined in detail one step in 60S ribosomal subunit assembly-processing of 27SA(3) pre

56 bm3 might enhance the association of 40S and 60S ribosomal subunits at 32 degrees C.

57 L22, a component of 60S ribosomal subunits, binds three sites on EBER-1, and

58 predominantly nucleolar and is required for 60S ribosomal subunit biogenesis and possibly for transl

59 ak5, Mtr4, Drs1, Spb4, and Dbp9) involved in 60S ribosomal subunit biogenesis.

60 ski6-2 mutant has normal amounts of 40S and 60S ribosomal subunits but accumulates a 38S particle co

61 NX increased the content of not only 40S and 60S ribosomal subunits but also 80S monosomes and polyso

62 xpressed in yeast cells associates with free 60S ribosomal subunits but not with 80S monosomes or pol

63 dimented through sucrose gradients with free 60S ribosomal subunits but not with 80S monosomes or pol

64 ted in a selective reduction in the level of 60S ribosomal subunits, causing a stoichiometric imbalan

65 led that the RQC forms a stable complex with 60S ribosomal subunits containing stalled polypeptides a

66 Nuclear export of the large (60S) ribosomal subunit depends on the adapter protein Nm

67 n of any steps prior to the rejoining of the 60S ribosomal subunit during the entire translation init

68 A selective autophagic pathway for 60S ribosomal subunits elicited by nitrogen starvation i

69 The FXR proteins are associated with 60S ribosomal subunits even in cells that lack FMR1 and

70 23p-mediated nuclear import of the essential 60S ribosomal subunit export factor, Nmd3p, and a DeltaR

71 protein Nmd3 is an adaptor for export of the 60S ribosomal subunit from the nucleus.

72 Here, by isolating late cytoplasmic 60S ribosomal subunits from Sbds-deleted mice, we show t

73 We found that L13a is released from the 60S ribosomal subunit in response to infection by respir

74 developed to follow the localization of the 60S ribosomal subunit in S. cerevisiae.

75 that a fraction of Rbm3 was associated with 60S ribosomal subunits in an RNA-independent manner.

76 The synthesis of 60S ribosomal subunits in Saccharomyces cerevisiae requi

77 revealed a modest increase in the amount of 60S ribosomal subunits in the ydj1-151 strain, consisten

78 ich may account for the selective deficit of 60S ribosomal subunits in these cells.

79 The biogenesis of the large (60S) ribosomal subunit in eukaryotes involves nucleolar,

80 The FMR1/FXR proteins also contain a 60S ribosomal subunit interaction domain and a protein-p

81 The 60S ribosomal subunit is one of the bulkiest transport c

82 essing of the ribosomal RNA component of the 60S ribosomal subunit is severely reduced, leading to an

83 ), or a defect in eIF5, proteins involved in 60S ribosomal subunit joining, specifically reduces the

84 that the interaction of the intron with the 60S ribosomal subunit leads to irreversible changes in t

85 Here we show that a specific reduction of 60S ribosomal subunit levels slows aging in yeast.

86 Thus, our data link defective late 60S ribosomal subunit maturation to an inherited bone ma

87 ccharomyces cerevisiae gene, which encodes a 60S ribosomal subunit protein required for joining of 40

88 that the addition of an NES directly to the 60S ribosomal subunit protein Rpl3 promotes export.

89 1 is a highly conserved gene which encodes a 60S ribosomal subunit protein that is required for joini

90 ccharomyces cerevisiae gene, which encodes a 60S ribosomal subunit protein.

91 tes, which were accompanied by decreased 40S/60S ribosomal subunit ratios.

92 bited the nuclear export of both the 40S and 60S ribosomal subunits, reduced the available pool of cy

93 Mutants deficient in 60S ribosomal subunits replicate L-A poorly, but not if

94 In eukaryotes, nuclear export of the large (60S) ribosomal subunit requires the adapter protein Nmd3

95 lation and inhibit the nuclear export of the 60S ribosomal subunit, respectively.

96 lacking PRMT3 showed an accumulation of free 60S ribosomal subunits resulting in an imbalance in the

97 of half-mer polyribosomes, reduced levels of 60S ribosomal subunits resulting in the stoichiometric i

98 tional surveillance, acts as an inhibitor of 60S ribosomal subunit ribophagy and is antagonized by Ub

99 ntify a novel mammalian complex required for 60S ribosomal subunit synthesis, providing further insig

100 omal protein L13a and translocation from the 60S ribosomal subunit to the interferon-gamma-activated

101 protein prevents association between 40S and 60S ribosomal subunits to form 80S ribosomes.

102 Ltn1 binds to 60S ribosomal subunits to ubiquitylate nascent polypepti

103 transported to the cytoplasm as part of the 60S ribosomal subunit, using a CRM1-dependent pathway.

104 nucleolar localization, and association with 60S ribosomal subunits were found to map to the amino ac

105 L260c are defective in the maturation of the 60S ribosomal subunit, whereas maturation of the 40S sub

106 f ubiquitinated polypeptides associated with 60S ribosomal subunits, while Dom34-Hbs1 generate 60S-as