ライフサイエンスコーパス: A-channel

1 A channel can allow for a reaction intermediate generate

2 A channel chimera of Orai3 with the N terminus of Orai1

3 A channel closing switch operated by calsequestrin depol

4 A channel configuration for the elimination of end effec

5 A channel electrophoresis system consisting of a 50 micr

6 A channel extends through the wafer from the tip of the

7 A channel fragment that connects S6 and the CaM-binding

8 A channel leading to the active site is sufficiently lar

9 A channel of variable width and depth that runs across t

10 A channel was defined as a series of matching pace-maps

11 A channel width was >/=0.6mm deemed critical to meet the

12 A channel-like region at the center of the S1-S4 helical

13 A channeling assay that optically detects solution-phase

14 assessed the influence of residues in the 11 A channel of the HDAC1 active site on activity by using

15 rate analog results in the formation of a 20 A channel connecting the active site for glutamine hydro

16 ecedented arrangement on either side of a 20-A channel.

17 RNAPII forms an extended, approximately 240 A channel that interacts with promoter DNA both upstream

18 f the enzyme, occupies a previously noted 25 A channel in the protein structure.

19 ring, producing an assembly surrounding a 60 A channel.

20 s a dimer of dimers, with an approximately 9 A channel in the center of the tetramer.

21 hannels) as well as astrocytes themselves (A/A channels).

22 O/A channels must be heterotypic, whereas A/A channels may be homotypic or heterotypic.

23 detected L- (alpha1(C)) and P/Q-type (alpha1(A)) channels in lysates of the Hermissenda nervous syste

24 Erb had no effect upon another A-channel, Kv4.3, which does not utilize the ball-and-ch

25 he colicin channel, particularly the colicin A channel, is selective for protons over other cations (

26 Two genes encode A-channels in this system, shaker and shal.

27 lation-dependent regulation of Kv4.2-encoded A channels by PKA.

28 ptors in PFC pyramidal neurons inhibits GABA(A) channel functions by regulating the PKA/PP1 signaling

29 ABA-mediated currents and gating of the GABA(A) channel by steroids, as well as steroid-induced anest

30 Furthermore, the GABA(A) channel reversal potential for chloride ions was posi

31 1 cells exhibited spontaneously opening GABA(A) channels not seen in patches excised from control GFP

32 ially desensitizing rather than opening GABA(A) channels.

33 ults in the outward flux of Cl- through GABA(A) channels, the opposite direction compared with mature

34 lobutane (F3), was found to alter gramicidin A channel function by enhancing Na(+) transport.

35 static effects of surface charge, gramicidin A channel conductance is also influenced by lipid-depend

36 ions of HCl, proton mobilities in gramicidin A channel and in solution differ by only 25%.

37 obutane causes minimal changes in gramicidin A channel structure in sodium dodecyl sulfate micelles.

38 of protons in a dioxolane-linked gramicidin A channel (D1) is comparable to the mobility of protons

39 eoisomers of the dioxolane-linked gramicidin A channel (the SS and RR dimers) were measured in a wide

40 charge and gauge its influence on gramicidin A channel conductance by two strategies: titration of th

41 Using a cation-selective gramicidin A channel as a sensor of the membrane surface charge, we

42 f the monovalent cation selective gramicidin A channel through single channel conductance, the closed

43 roposed for the membrane-spanning gramicidin A channel: one based on solid-state NMR experiments in o

44 high-resolution structure of the gramicidin A channel in lamellar phase lipids and the characterizat

45 PMF profile of the ion along the Gramicidin A channel is obtained by combining an equilibrium molecu

46 ion permeation energetics in the gramicidin A channel using a novel polarizable force field.

47 ct the secondary structure of the gramicidin A channel.

48 Gramicidin A channels are miniproteins that are anchored to the int

49 F-Indole)Trp(13) gramicidin A and gramicidin A channels (, 75:2830-2844).

50 hat 1) The mobility of protons in gramicidin A channels in different lipid bilayers is remarkably sim

51 es between proton conductances in gramicidin A channels in GMO and PEPC cannot be explained by surfac

52 ynamics of water molecules inside gramicidin A channels is modulated by the lipid environment and by

53 We find that the sensitivity of gramicidin A channels to the anesthetic halothane is highly lipid d

54 on the structure and function of gramicidin A channels.

55 analyzed in side-chain analogs of gramicidin A channels.

56 he effect of Hofmeister anions on gramicidin A channels in lipid membranes.

57 ubstitutions in membrane-spanning gramicidin A channels.

58 governing K(+) conduction through gramicidin A channels is characterized by using over 0.1 micros of

59 Using gramicidin A channels as a tool to probe bilayer mechanics, we show

60 equences of lipid diversity using gramicidin A channels embedded in phosphatidylcholine (PC) bilayers

61 component of native neuronal Kv4.2-encoded I(A) channel complexes and a novel regulator of I(A) chann

62 channel complexes and a novel regulator of I(A) channel densities and neuronal excitability.

63 Although I(A) channels are thought to play a role in synaptic proce

64 demonstrate that Kv1.4- and Kv4.2-encoded I(A) channels regulate the intrinsic excitability of SCN n

65 n the generation of functional Kv4-encoded I(A) channels.

66 cumulated demonstrating specific roles for I(A) channels in the generation of individual action poten

67 the coincident reappearance of functional I(A) channels.

68 ble evidence suggests that native neuronal I(A) channels function in macromolecular protein complexes

69 /-)), the pore-forming (alpha) subunits of I(A) channels.

70 Immunohistochemical data suggest that I(A) channels in hippocampal and cortical pyramidal neuron

71 generation of fast transient outward K(+), I(A), channels.

72 Mutations in K(A) channel auxiliary subunits may be loci for epilepsy.

73 st that is selective for binding to the NR2B/A channel subunit.

74 Js couple oligodendrocytes and astrocytes (O/A channels) as well as astrocytes themselves (A/A channe

75 press different connexins (Cx30 and Cx43), O/A channels must be heterotypic, whereas A/A channels may

76 on via activation of voltage-gated potassium A-channels (I(A)), found almost exclusively in the media

77 applications, a homology model of the Shaker A channel permeation path was constructed using the alig

78 s with alternate amino-termini such as Slack-A channels are present at these locations.

79 When expressed in CHO cells, Slack-A channels activate rapidly upon depolarization and, in

80 oximately 6-fold longer than those for Slack-A channels.

81 Neuronal expression of Slack-A channels and of the previously described Slack isoform

82 Two of these, termed Slack-A channels, contain an amino-terminus domain closely res

83 ntly, DEX blocked PKA activation of S4(STREX)A channels in a PP2A-dependent manner.

84 The A-channel antagonist 4-aminopyridine (4-AP) produced a v

85 urrent through two distinct K+ channels, the A-channel and the Ca2+-dependent K+ channel.

86 ld, while the opposite modification (TMEM16B-A channels) produced a approximately six-fold increase i

87 erted irreversibly into a population of Type A channels by the addition of La(3+).

88 ic acid 6), is the RBP4 receptor and vitamin A channel; however, the role of STRA6 in vitamin A homeo