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1 ty, properties that arise from its conserved AAA domain.
2  may be a general feature of ATP-hydrolyzing AAA domains.
3 ism for long-range communication between the AAA domains.
4 NifL-resistant phenotype of mutations in the AAA+ domain.
5 alpha-helix in the C-terminal portion of the AAA+ domain.
6 protein ClpB to provide a model of torsinA's AAA+ domain.
7 pha/beta and alpha-helical subdomains of the AAA+ domain.
8  coiled-coil domain intercalated between the AAA+ domains.
9 s at the top of the cylinder followed by two AAA+ domains.
10 terminal domain, an M-domain, and two tandem AAA(+) domains.
11                 The gene product contains an AAA domain, a putative leucine zipper and a phosphorylat
12 ontains an N-terminal domain (NSF-N) and two AAA domains, a catalytic NSF-D1 and a structural NSF-D2.
13                                     The DctD AAA+ domain activated transcription in vitro, but many o
14 f an N-terminal regulatory domain, a central AAA domain and a C-terminal DNA binding domain.
15  crystal structure of the Drosophila spastin AAA domain and provide a model for the active spastin he
16                       Vps4 contains a single AAA domain and undergoes ATP-dependent quaternary struct
17 nits contain calcium-signaling motifs and/or AAA domains and are nearly ubiquitous in species with mo
18 ormational changes that propagate to all six AAA domains and cause a large movement of the "linker,"
19 nucleotide binding or hydrolysis in the four AAA domains and examined the ability of the mutant dynei
20 ct double-stranded DNA through an N-terminal AAA(+) domain and a C-terminal winged-helix domain (WHD)
21 binding proteins (bEBPs) oligomerize through AAA(+) domains and use ATP hydrolysis-driven energy to i
22 r (FisR) with three domains: an R domain, an AAA+ domain and a DNA-binding domain.
23 es in controlling the oligomerization of the AAA+ domain and modulating interactions with sigma54 in
24  amino acid substitutions cluster within the AAA(+) domain at residues near the ATP-binding pocket.
25 reveals a closure of the motor's ring of six AAA+ domains (ATPases associated with various cellular a
26                                     The DctD AAA+ domain, but not DctD(Delta(1-142)), formed a stable
27 ments show that the helicase activity of the AAA+ domain can be stimulated by addition of the isolate
28         The origin dsDNA inside the narrower AAA+ domain channel shows partial melting due to the com
29      Structurally, the Rep proteins share an AAA(+) domain characteristic of superfamily 3 helicases,
30                    In dynein, the first four AAA domains contain consensus nucleotide triphosphate-bi
31      Overexpression of ATAD2 (ATPase family, AAA domain containing 2) has been linked to disease seve
32                                              AAA domain containing 3A (ATAD3A) is an integral mitocho
33                         ATAD3 (ATPase family AAA-Domain containing protein 3) is a mitochondrial inne
34                                ATPase family AAA-domain containing protein 3A (ATAD3A) is a nuclear-e
35 receptor trafficking: Thorase (ATPase family AAA domain-containing protein 1), soluble N-ethylmaleimi
36 n-containing proteins, such as ATPase family AAA domain-containing protein 2 (ATAD2), isoform A, have
37                      Mammalian ATPase family AAA domain-containing protein 5 (ATAD5) and its yeast ho
38                                          The AAA domain contains highly conserved motifs, the Walker
39 -terminal domain (N-domain) and the adjacent AAA domain (D1), resulting in a reduced affinity for ADP
40          p97 forms a hexamer composed of two AAA domains (D1 and D2) that form two stacked rings and
41 conserved Arg(359) and Arg(362) in the first AAA domain, D1 and Arg(635) and Arg(638) in the second A
42 , D1 and Arg(635) and Arg(638) in the second AAA domain, D2.
43 otation of more than 90 degrees for the Orc1 AAA+ domain disrupts interactions with catalytic amino a
44       Subsequent ATP hydrolysis in the first AAA domain dissociated Drg1 from Rlp24, liberating both
45                   Unlike the residues of the AAA+ domain DNA-binding segments (beta-hairpin and hydro
46 binding and hydrolysis in each of these four AAA domains has constituted an important and unresolved
47                             We find that the AAA(+) domain has an unpredicted role in controlling the
48 FIGL-1-AAA), in clear contrast to homologous AAA domains, has an unusually high ATPase activity and f
49  results show that the four conserved dynein AAA domains have distinct functions in dynein's mechanoc
50 minal Allosteric Communication Loop with the AAA+ domain helix-2-insert (h2i); and 3) a recessed bind
51 ts include the first analysis of the central AAA+ domain in isolation.
52 represses the ATPase activity of the central AAA+ domain in the absence of nitric oxide.
53  to a cysteine change upstream of the second AAA+ domain in the temperature sensitive TgNoAP1 allele
54                             The order of the AAA+ domains in the ring was determined by using recombi
55 down experiments show that the DnaC and DnaA AAA+ domains interact in a nucleotide-dependent manner.
56                     Although canonical inter-AAA+ domain interactions exist between four of the six O
57 minate prematurely, suggesting that the DctD AAA+ domain interfered with transcription elongation.
58  motor unit derives from the assembly of six AAA domains into a hexameric ring.
59                 But how the action of its 12 AAA+ domains is co-ordinated to catalyze disaggregation
60 imply that the wave's propagation within the AAA+ domains is not necessarily coupled with a strictly
61 domain, formed by a ring-like arrangement of AAA+ domains, is located approximately 280 A away from t
62 GAF domain restores inhibition by NifL to an AAA+ domain mutation, E356K, in response to fixed nitrog
63                         In the absence of an AAA+ domain mutation, the F119S mutation confers hyperse
64 e 216 falls in the N-terminal portion of the AAA+ domain near the sensor 1 motif.
65            Inhibitor binding into the second AAA domain of Drg1 requires ATP loading and results in i
66                 ATP hydrolysis in the second AAA domain of Drg1 was required to release shuttling pro
67 n experiments also showed that the catalytic AAA domain of FtsH contains a chaperone-like activity, h
68 nd mammals, Hsm3 actually directly binds the AAA domain of Rpt2.
69                       Here, we show that the AAA domain of the Caenorhabditis elegans FIGL-1 protein
70 f P-loop function within the first and third AAA domains of the Drosophila cytoplasmic dynein heavy c
71 support current models in which the multiple AAA domains of the dynein heavy chain interact to suppor
72                               The N-terminal AAA(+) domain of ChlD is essential for complex formation
73 ce of MgADP, and we show that the N-terminal AAA(+) domain of ChlD mediates this process, in agreemen
74             Using a series of mutants in the AAA(+) domain of ChlD, we show that this site is essenti
75 x high resolution structures (<2.1 A) of the AAA(+) domain of EBP phage shock protein F (PspF) includ
76 nit dynamics and nucleotide occupancy of the AAA(+) domain of one well-studied bEBP in complex with i
77  describe the first structure of the central AAA(+) domain of the flagellar regulatory protein FlrC (
78  and specifically acts upon and binds to the AAA(+) domain of the PspF transcription activator.
79 inimal functional C-terminal boundary of the AAA+ domain of DctD as being located between Gly-381 and
80  report that Soj directly interacts with the AAA+ domain of DnaA and specifically regulates DnaA heli
81 s involved in nucleotide binding, and of the AAA+ domain of DnaC.
82 topoisomerase IV (Topo IV) by the C-terminal AAA+ domain of FtsK.
83 idence for a DNA-interacting activity in the AAA+ domain of PspF was obtained, suggesting that PspF m
84                                          The AAA+ domain of Sinorhizobium meliloti C4-dicarboxylic ac
85                             In bacteria, the AAA+ domain of the initiator DnaA has been proposed to a
86 howing that the ADP.AlF(x) bound form of the AAA+ domain of the transcriptional activator protein Psp
87 vely removes the hydrophobic domain from the AAA+ domain of TorsinA, which retains catalytic activity
88 rotease requires collaboration among the six AAA+ domains of ClpX.
89 nges in rotation between the large and small AAA+ domains of individual subunits.
90  to NifL are located in both the GAF and the AAA+ domains of NifA.
91 associated with various cellular activities (AAA+) domain of the Escherichia coli activator protein,
92                     This enzyme contains two AAA(+) domains, one active in the ChlI protein and one i
93   Structures of the sigma(54) activator PspF AAA+ domain (PspF(1-275)) bound to sigma(54) show two lo
94                                     The PspF AAA(+) domain, PspF(1-275), remodels the bacterial sigma
95                  Conserved regions of PspF's AAA(+) domain respond distinctively to nucleotide bindin
96 ween two helical pentamers of ATP-associated AAA+ domains, sharply bending the duplex into a 180 degr
97 l ATPase associated with various activities (AAA) domain, specifically alpha-helices 7 and 9, as rele
98   Through proposed fitting of representative AAA domain structures, we show that the nucleotide catal
99 locus include CbbO and CbbQ, a member of the AAA+ domain superfamily.
100 -1-AAA are not conserved in other homologous AAA domains that have relatively low ATPase activities.
101 share two domains: a modified version of the AAA(+) domain that characterizes the SF3 family of helic
102  NorR by characterizing substitutions in the AAA+ domain that bypass repression by the regulatory dom
103                These proteins have conserved AAA+ domains that catalyse ATP hydrolysis to drive confo
104 built upon interactions between neighbouring AAA+ domains, that in vitro stretches DNA to promote rep
105 ows that CsoCbbQ is a hexamer of the typical AAA+ domain; the additional C-terminal domain, diagnosti
106 interaction surface to prevent access of the AAA+ domain to the sigma factor.
107  a continuous surface that allows successive AAA+ domains to bind and extend single-stranded DNA segm
108 built upon interactions between neighbouring AAA+ domains to form an active initiation complex.
109        Our results demonstrate that the free AAA(+) domain undergoes significant changes in oligomeri
110               A region of ClpC containing an AAA domain was necessary and sufficient for polar locali
111                        In addition, the DctD AAA+ domain was more homogeneous than DctD(Delta(1-142))
112                                     The DctD AAA+ domain was significantly more soluble than DctD(Del
113 the GAF domain regulates the activity of the AAA+ domain, we screened for second-site mutations that
114  of site-specifically modified, cross-linked AAA+ domains, we found that the conserved arginine pair
115        Histidine-tagged versions of the DctD AAA+ domain were purified and characterized.
116 al DNA contacts are made with the N-terminal AAA+ domain, which inserts into the minor groove at a ch
117 ynein motor domain consists of a ring of six AAA domains with a protruding microtubule-binding stalk

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